nifedipine has been researched along with Myocardial Ischemia in 104 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
Excerpt | Relevance | Reference |
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"We sought to determine the effect of nifedipine gastrointestinal therapeutic system (GITS) or atenolol on ischemic left ventricular dysfunction induced by mental stress." | 9.08 | Effects of therapy with nifedipine GITS or atenolol on mental stress-induced ischemic left ventricular dysfunction. ( Andrews, TC; Carlson, W; Cummings, N; Friedman, R; Jacobs, S; MacCallum, G; Mannting, F; Muller, JE; Parker, JD; Stone, PH; Tofler, GH, 1998) |
"In a randomized, cross-over, double-blind study, the effects of nifedipine were compared with those of diltiazem in 20 patients with severe stable angina pectoris and multivessel coronary artery disease treated with nitrates and beta-blockers." | 9.07 | Effects of nifedipine and diltiazem on myocardial ischemia in patients with severe stable angina pectoris treated with nitrates and beta-blockers. ( Meluzín, J; Simek, P; Stĕtka, F; Zeman, K, 1992) |
"META-ANALYSIS: A meta-analysis of published randomized control trials of nifedipine in hypertension and stable angina pectoris was performed." | 8.79 | Searching for signals: mortality and cardiovascular events in published randomized control trials of nifedipine in ischemic heart disease and hypertension. ( Caubet, JF; Chalmers, TC; Cory, D; Kupelnick, B; Ross, SD; Schmid, CH; Stason, W; Whiting, G, 1996) |
"In patients with coronary disease, the use of short-acting nifedipine in moderate to high doses causes an increase in total mortality." | 8.79 | Nifedipine. Dose-related increase in mortality in patients with coronary heart disease. ( Furberg, CD; Meyer, JV; Psaty, BM, 1995) |
" The effects of the calcium channel blockers, verapamil and nifedipine on myocardial ischaemia and oedema evoked by endothelin-1 (ET-1) or IRL 1620, an ETB receptor-selective agonist were studied in anaesthetized and conscious rats." | 7.69 | Effects of calcium antagonists on endothelin-1-induced myocardial ischaemia and oedema in the rat. ( Filep, JG; Földes-Filep, E; Fournier, A; Skrobik, Y, 1996) |
"Effects of CD-832 on isoproterenol (ISO)-induced myocardial ischemia were studied in dogs with partial coronary stenosis of the left circumflex coronary artery and findings were compared with those for nifedipine or diltiazem." | 7.69 | Effects of a new calcium antagonist, CD-832, on isoproterenol-induced myocardial ischemia in dogs with partial coronary stenosis. ( Araki, H; Higuchi, S; Kishi-Tanikawa, S; Takahashi, K; Takahashi, T; Tsuchida, K, 1996) |
"Gingival hyperplasia caused by the use of nifedipine has been extensively reported." | 7.69 | Clinical assessment of gingival hyperplasia in patients treated with nifedipine. ( Bullon, P; Lacalle, JR; Machuca, G; Martinez-Sahuquillo, A; Rios, JV; Rojas, J, 1994) |
"We investigated the effect of abrupt cessation of nifedipine after regular administration (20 mg, four times daily) for 5 weeks in seven patients with stable angina pectoris." | 7.68 | Withdrawal phenomenon after abrupt cessation of nifedipine in stable angina pectoris. ( Koutishenko, N; Martsevich, SY; Metelitsa, VI, 1993) |
"To compare the negative inotropic effects of the four dihydropyridine-calcium-channel-blockers nifedipine (NIF), isradipine (ISR), nisoldipine (NIS) and felodipine (FEL) in man, the drugs were infused within 30 min intravenously in an equihypotensive dosage (NIF 2 mg, ISR 0." | 6.67 | [Comparison of the cardiodepressive effects of nifedipine, isradipine, nisoldipine and felodipine in patients with coronary heart disease]. ( Ickrath, O; Karsch, KR; Mauser, M; Voelker, W, 1993) |
"Nifedipine was administered to 20 patients (8 in group 1, and 12 in group 2)." | 6.67 | Transient myocardial ischemia during nifedipine therapy in stable angina pectoris, and its relation to coronary collateral flow and comparison with metoprolol. ( Andersen, PE; Egstrup, K, 1993) |
"A randomized study was performed on 70 patients undergoing elective coronary bypass grafting to examine whether the combined infusion of the calcium channel blocker nifedipine (10 micrograms/kg per hour) and the beta 1-blocker metopropol (12 micrograms/kg per hour, n = 34) reduces the prevalence of perioperative myocardial ischemia and arrhythmias." | 5.08 | Comparison of perioperative myocardial protection with nifedipine versus nifedipine and metoprolol in patients undergoing elective coronary artery bypass grafting. ( Binder, TM; Podesser, BK; Schwarzacher, S; Seitelberger, R; Wolner, E; Zwoelfer, W, 1995) |
"We compared the effects of bisoprolol on transient myocardial ischemia with those of nifedipine in patients with chronic stable angina." | 5.08 | Medical treatment to reduce total ischemic burden: total ischemic burden bisoprolol study (TIBBS), a multicenter trial comparing bisoprolol and nifedipine. The TIBBS Investigators. ( von Arnim, T, 1995) |
"The effects of bisoprolol on transient myocardial ischemia have been compared with those of nifedipine in patients with coronary artery disease in end-stage renal failure maintained on haemodialysis." | 5.08 | [Effectiveness and tolerability of bisoprolol vs. nifedipine in uremic patients with ischemic cardiopathy in dialysis treatment]. ( Cice, G; Di Benedetto, A; Ferrara, L; Iacono, A; Sorice, P; Tagliamonte, E, 1997) |
"We sought to determine the effect of nifedipine gastrointestinal therapeutic system (GITS) or atenolol on ischemic left ventricular dysfunction induced by mental stress." | 5.08 | Effects of therapy with nifedipine GITS or atenolol on mental stress-induced ischemic left ventricular dysfunction. ( Andrews, TC; Carlson, W; Cummings, N; Friedman, R; Jacobs, S; MacCallum, G; Mannting, F; Muller, JE; Parker, JD; Stone, PH; Tofler, GH, 1998) |
" Patients of stable angina pectoris treated with Radix Codonopsitis Pilosulae (50 cases) or Nifedipine (20 cases) were observed as well." | 5.08 | [Clinical study on relationship among Heart-Qi Deficiency, left ventricular function and myocardial ischemia in patients with coronary heart disease]. ( Lu, X; Wang, S; Zhao, M, 1998) |
"A randomised study was performed on 70 patients undergoing elective coronary by-pass procedure to examine whether the combined, perioperative, 24-hour infusion of nifedipine and metoprolol reduces the incidence of perioperative myocardial ischemia and arrhythmias." | 5.07 | Perioperative infusion of nifedipine and metoprolol provides antiischemic and antiarrhythmic protection in patients undergoing elective aortocoronary by-pass surgery. ( Binder, T; Huber, S; Peschl, F; Podesser, B; Schwarzacher, S; Seitelberger, R; Spatt, J; Wolner, E; Zwölfer, W, 1994) |
"A randomized study was performed on 70 patients undergoing elective coronary bypass surgery to examine whether the combined, perioperative, 24-hour infusion of the calcium-channel blocker nifedipine (10 micrograms/kg/h) and the beta 1-blocker metoprolol (12 micrograms/kg/h) reduces the incidence of perioperative myocardial ischemia and arrhythmias (group NM, n = 34)." | 5.07 | Combined perioperative infusion of nifedipine and metoprolol provides antiischemic and antiarrhythmic protection in patients undergoing elective aortocoronary bypass surgery. ( Binder, TM; Huber, S; Peschl, F; Podesser, B; Schwarzacher, S; Seitelberger, R; Spatt, J; Zwölfer, W, 1993) |
"The effects of verapamil, nifedipine, propranolol, and combinations of nifedipine+propranolol and nifedipine+verapamil were studied in 60 patients with stable angina pectoris." | 5.07 | [Effect of various antianginal agents on the frequency and duration of myocardial ischemic episodes in patients with stable angina pectoris]. ( Lysenko, AF; Voronkov, LG, 1992) |
"In a randomized, cross-over, double-blind study, the effects of nifedipine were compared with those of diltiazem in 20 patients with severe stable angina pectoris and multivessel coronary artery disease treated with nitrates and beta-blockers." | 5.07 | Effects of nifedipine and diltiazem on myocardial ischemia in patients with severe stable angina pectoris treated with nitrates and beta-blockers. ( Meluzín, J; Simek, P; Stĕtka, F; Zeman, K, 1992) |
"META-ANALYSIS: A meta-analysis of published randomized control trials of nifedipine in hypertension and stable angina pectoris was performed." | 4.79 | Searching for signals: mortality and cardiovascular events in published randomized control trials of nifedipine in ischemic heart disease and hypertension. ( Caubet, JF; Chalmers, TC; Cory, D; Kupelnick, B; Ross, SD; Schmid, CH; Stason, W; Whiting, G, 1996) |
"In patients with coronary disease, the use of short-acting nifedipine in moderate to high doses causes an increase in total mortality." | 4.79 | Nifedipine. Dose-related increase in mortality in patients with coronary heart disease. ( Furberg, CD; Meyer, JV; Psaty, BM, 1995) |
"Electron paramagnetic resonance (EPR) spectroscopy was used to investigate the gamma-radiation damage in the crystalline powder form of nine calcium channel blockers from the 1,4-dihydropyridine derivatives, which are in clinical use for treatment of arteria hypertension and ischemic heart disease." | 3.74 | The effect of ionizing radiation of 1,4-dihydropyridine derivatives in the solid state. ( Mielcarek, J; Naskrent, M, 2007) |
" The effects of diltiazem, verapamil, and nifedipine on extracellular potassium concentration ([K+]e), acidosis, and level of metabolic markers were examined during 30-min global ischemia and postischemic left ventricular (LV) function in isolated guinea pig hearts." | 3.70 | Temporal differences in actions of calcium channel blockers on K+ accumulation, cardiac function, and high-energy phosphate levels in ischemic guinea pig hearts. ( Nagao, T; Sato, R; Yamazaki, J, 1999) |
"The effects of the Ca2+ channel blockers diltiazem, nifedipine and amlodipine were investigated on both arterial hypertension and myocardial changes induced by chronic blockade of nitric oxide synthesis." | 3.70 | Effect of Ca2+ channel blockers on arterial hypertension and heart ischaemic lesions induced by chronic blockade of nitric oxide in the rat. ( Antunes, E; de Luca, IM; de Nucci, G; de Oliveira, CF; Metze, K; Moreno, H; Nathan, LP; Sucupira, M; Zappellini, A; Zatz, R, 1999) |
"These results indicate that the calcium channel blocker nifedipine mediates coronary vasodilation and improves myocardial ischemia through both bradykinin/NO-dependent and -independent mechanisms." | 3.70 | Nifedipine-induced coronary vasodilation in ischemic hearts is attributable to bradykinin- and NO-dependent mechanisms in dogs. ( Asakura, M; Asanuma, H; Hori, M; Kitakaze, M; Kuzuya, T; Minamino, T; Sakata, Y; Sanada, S; Takashima, S; Ueda, Y, 2000) |
"Effects of CD-832 on isoproterenol (ISO)-induced myocardial ischemia were studied in dogs with partial coronary stenosis of the left circumflex coronary artery and findings were compared with those for nifedipine or diltiazem." | 3.69 | Effects of a new calcium antagonist, CD-832, on isoproterenol-induced myocardial ischemia in dogs with partial coronary stenosis. ( Araki, H; Higuchi, S; Kishi-Tanikawa, S; Takahashi, K; Takahashi, T; Tsuchida, K, 1996) |
"The effect of abrupt discontinuation of nifedipine (N) on exercise tolerance and myocardial ischemia was studied in 7 patients with stable angina pectoris of effort (AP)." | 3.69 | [The nifedipine withdrawal syndrome in patients with stable stenocardia of effort]. ( Kutishenko, NP; Martsevich, SIu; Metelitsa, VI, 1995) |
" But in a pig model of myocardial ischemia, intracoronary nifedipine was found to reverse the inverted T wave induced by ischemia to upright promptly." | 3.69 | [Effect of nifedipine on T wave in ischemic myocardium]. ( He, X; Huang, N; Li, X; Shen, X; Wang, S, 1994) |
" The effects of the calcium channel blockers, verapamil and nifedipine on myocardial ischaemia and oedema evoked by endothelin-1 (ET-1) or IRL 1620, an ETB receptor-selective agonist were studied in anaesthetized and conscious rats." | 3.69 | Effects of calcium antagonists on endothelin-1-induced myocardial ischaemia and oedema in the rat. ( Filep, JG; Földes-Filep, E; Fournier, A; Skrobik, Y, 1996) |
"To evaluate the effect of acute blood pressure (BP) changes on the myocardial perfusion in hypertensives, 10 patients with and 10 patients without left ventricular hypertrophy (LVH) were examined with 99TCm-Sestamibi scintigraphy at rest and after acute pharmacological BP reduction using nifedipine and captopril." | 3.69 | Blood pressure and myocardial perfusion in hypertensive patients with and without left ventricular hypertrophy. ( Berglund, G; Boström, PA; Diemer, H; Lilja, B; Mansour, P; Mattiasson, I; Nehoum, A, 1995) |
"Gingival hyperplasia caused by the use of nifedipine has been extensively reported." | 3.69 | Clinical assessment of gingival hyperplasia in patients treated with nifedipine. ( Bullon, P; Lacalle, JR; Machuca, G; Martinez-Sahuquillo, A; Rios, JV; Rojas, J, 1994) |
"We investigated the effect of abrupt cessation of nifedipine after regular administration (20 mg, four times daily) for 5 weeks in seven patients with stable angina pectoris." | 3.68 | Withdrawal phenomenon after abrupt cessation of nifedipine in stable angina pectoris. ( Koutishenko, N; Martsevich, SY; Metelitsa, VI, 1993) |
"Therapy with OSMO-Adalat of patients with AH combination with KPA provides a good hypotensive effect and relieves symptoms of encephalopathy, myocardial ischemia and orthostatic insufficiency in low risk of side effects." | 2.70 | [Efficacy of OSMO-Adalat in patients with arterial hypertension in combination with kinked precerebral arteries]. ( Khirmanov, VN; Sorokoumov, VA; Tiurina, TV; Zakharova, IV, 2001) |
"Fourteen patients with ischemic heart disease (12 men and two women; mean age 64 years) were administered nifedipine retard at a daily dose of 20-40 mg." | 2.70 | Effects of nifedipine retard on heart rate and autonomic balance in patients with ischemic heart disease. ( Aizawa, T; Arai, H; Fukuda, E; Long-Tai, FL; Sato, H; Tsutsumi, Y; Yamamoto, M, 2001) |
"Of them 36 had dilated cardiomyopathy (DC), 30 ischemic heart disease (IHD), 19 suffered from essential hypertension (EH)." | 2.67 | [Differential use of vasodilators in various types of cardiac insufficiency]. ( Cheltsov, VV; Moiseev, VS; Shatkovskiĭ, NP, 1993) |
"To compare the negative inotropic effects of the four dihydropyridine-calcium-channel-blockers nifedipine (NIF), isradipine (ISR), nisoldipine (NIS) and felodipine (FEL) in man, the drugs were infused within 30 min intravenously in an equihypotensive dosage (NIF 2 mg, ISR 0." | 2.67 | [Comparison of the cardiodepressive effects of nifedipine, isradipine, nisoldipine and felodipine in patients with coronary heart disease]. ( Ickrath, O; Karsch, KR; Mauser, M; Voelker, W, 1993) |
" After a 4 week run-in period on atenolol, patients were randomly allocated to receive either atenolol alone or its combination with nifedipine and then crossed over to the alternative treatment for a further 4 weeks." | 2.67 | Comparison of the efficacy of atenolol and its combination with slow-release nifedipine in chronic stable angina. ( Adnams, C; Commerford, P; Meyer, TE, 1993) |
" Nifedipine at a dosage of 200 micrograms or placebo was added to each 1000 ml of St." | 2.67 | Cardioprotection by nifedipine cardioplegia during coronary artery surgery. ( Haider, W; Laczkovics, A; Moritz, A; Trubel, W; Zwoelfer, W, 1994) |
"Nifedipine was administered to 20 patients (8 in group 1, and 12 in group 2)." | 2.67 | Transient myocardial ischemia during nifedipine therapy in stable angina pectoris, and its relation to coronary collateral flow and comparison with metoprolol. ( Andersen, PE; Egstrup, K, 1993) |
" During the chronic use of long-acting dihydropyridine (DHP) CCBs, most evidence suggests that there is little or no catecholamine activation, or in the case of amlodipine, even a decrease in plasma catecholamine levels." | 2.40 | Calcium channel blockers for hypertension: dissecting the evidence for adverse effects. ( Opie, LH, 1997) |
" However, the direct cardiotoxicity in vitro and its mechanisms of toxic action remain unclear." | 1.38 | Direct cardiac toxicity of the tentacle-only extract from the jellyfish Cyanea capillata demonstrated in isolated rat heart. ( Beilei, W; Jia, L; Liang, X; Liming, Z; Lin, Z; Qian, H; Qianqian, W; Tao, W; Xiaojuan, W; Xuting, Y, 2012) |
" Chronic administration (45 days) produced no toxic effects in vital organs and systems of Wistar rats and ISIAH rats." | 1.37 | Glycidipine, a promising hypotensive and cardioprotective agent. ( Belenichev, IF; Bryzgalov, AO; Khvostov, MV; Pavlov, SV; Tolstikova, TG, 2011) |
"Diltiazem has cardioprotective properties following myocardial ischemic injury." | 1.31 | Protective effect of diltiazem against ischemia-induced decreases in regional myocardial flow in rat heart. ( Higuchi, H; Katsumata1, N; Ma, X, 2000) |
"38 patients with ischemic heart disease (IHD) and sick sinus syndrome (SSS) received combined therapy with nifedipine (Corinfar-Retard) and talinolol (Cordanum)." | 1.30 | [The use of Cordanum in combination with Corinfar-Retard for the treatment of ectopic arrhythmias in the sick sinus syndrome in patients with ischemic heart disease]. ( Arsent'eva, NR; Chernova, EV; Doshchitsin, VL; Kuchinskaia, NG; Lindo, IN; Martynova, VN; Shatukhina, EIu, 1997) |
"Nisoldipine did not produce any beneficial effect without the inhibition of the increase in end-diastolic pressure during ischemia nor did it do so without the increase of reperfusion flow." | 1.29 | Improvement of ischemic myocardial dysfunction by nisoldipine in relation to its coronary vasodilating action. ( Saida, K; Umeda, M, 1993) |
"Nifedipine was applied in a concentration (EC50) known to reduce the contractile force by one-half of its basal value." | 1.29 | Cardioprotection by nifedipine in isolated working hearts: a comparative study on three different types of experimental ischemia. ( Mathy, MJ; Pfaffendorf, M; Pijl, AJ; van Zwieten, PA, 1993) |
" First, dose-response curves were constructed; from these data the EC50 concentration for the three calcium antagonists was calculated." | 1.29 | Hemodynamic and antiischemic effects of nifedipine, lacidipine, and nisoldipine in rat isolated working heart. ( Pfaffendorf, M; Pijl, AJ; van Zwieten, PA, 1993) |
"Nifedipine was the most effective with only 5 +/- 2% reduction in blood flow after five ischaemic episodes, whereas reduction of myocardial blood flow was 30 +/- 4% in the presence of gallopamil." | 1.29 | Preservation of myocardial blood flow by calcium antagonists does not prevent attenuation of regional myocardial function after repetitive brief periods of myocardial ischaemia in the rat heart. ( Amann, K; Kübler, W; Parekh, N; Rauch, B; Tiefenbacher, CP; Tillmanns, H; Zimmermann, R, 1995) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 82 (78.85) | 18.2507 |
2000's | 19 (18.27) | 29.6817 |
2010's | 3 (2.88) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Beilei, W | 1 |
Lin, Z | 1 |
Qian, H | 1 |
Qianqian, W | 1 |
Tao, W | 1 |
Jia, L | 1 |
Xiaojuan, W | 1 |
Xuting, Y | 1 |
Liang, X | 1 |
Liming, Z | 1 |
Tolstikova, TG | 1 |
Khvostov, MV | 1 |
Bryzgalov, AO | 1 |
Belenichev, IF | 1 |
Pavlov, SV | 1 |
Mamedov, MN | 1 |
Möllhoff, T | 1 |
Schmidt, C | 1 |
Van Aken, H | 1 |
Berendes, E | 1 |
Buerkle, H | 1 |
Marmann, P | 1 |
Reinbold, T | 1 |
Prenger-Berninghoff, R | 1 |
Tjan, TD | 1 |
Scheld, HH | 1 |
Deng, MC | 1 |
Altura, BM | 1 |
Kostellow, AB | 1 |
Zhang, A | 1 |
Li, W | 1 |
Morrill, GA | 1 |
Gupta, RK | 1 |
Altura, BT | 1 |
Huelsing, DJ | 1 |
Spitzer, KW | 1 |
Pollard, AE | 1 |
Camara, AK | 1 |
Chen, Q | 1 |
Rhodes, SS | 1 |
Riess, ML | 1 |
Stowe, DF | 1 |
Higashikuni, Y | 1 |
Sata, M | 1 |
Nagai, R | 1 |
Karpov, IuA | 1 |
Kosicka, T | 1 |
Kara-Perz, H | 1 |
Głuszek, J | 1 |
Perz, S | 1 |
Naskrent, M | 1 |
Mielcarek, J | 1 |
Noda, T | 1 |
Yaginuma, T | 1 |
O'Rourke, MF | 1 |
Hosoda, S | 1 |
Podesser, BK | 1 |
Schwarzacher, S | 3 |
Zwoelfer, W | 2 |
Binder, TM | 2 |
Wolner, E | 2 |
Seitelberger, R | 3 |
Pijl, AJ | 3 |
Pfaffendorf, M | 3 |
van Zwieten, PA | 3 |
Hendriks, MG | 1 |
Kam, KL | 1 |
Wout van den Toren, E | 1 |
de Vries, RJ | 1 |
Portegies, MC | 1 |
Blanksma, PK | 1 |
van Gilst, WH | 1 |
Hillege, HJ | 1 |
van Veldhuisen, DJ | 1 |
Lie, KI | 1 |
Mazur, NA | 1 |
Pavlova, TS | 1 |
Vasil'eva, NN | 1 |
Kul'ginskaia, IV | 1 |
Furberg, CD | 1 |
Psaty, BM | 1 |
Meyer, JV | 1 |
Martsevich, SIu | 2 |
Kutishenko, NP | 1 |
Metelitsa, VI | 2 |
Mathy, MJ | 1 |
Podesser, B | 2 |
Zwölfer, W | 2 |
Binder, T | 1 |
Spatt, J | 2 |
Peschl, F | 2 |
Huber, S | 2 |
von Arnim, T | 3 |
Molodan, AV | 1 |
Salgalov, AV | 1 |
Osaulenko, VV | 1 |
Materukhin, AN | 1 |
Wang, S | 2 |
Shen, X | 1 |
Li, X | 1 |
Huang, N | 1 |
He, X | 1 |
Palócz, E | 1 |
Kerkovits, G | 1 |
Pepine, CJ | 4 |
Geller, NL | 3 |
Knatterud, GL | 4 |
Bourassa, MG | 2 |
Chaitman, BR | 2 |
Davies, RF | 3 |
Day, P | 1 |
Deanfield, JE | 1 |
Goldberg, AD | 2 |
McMahon, RP | 2 |
Sopko, G | 3 |
Pratt, C | 2 |
Stone, PH | 5 |
Rogers, WJ | 1 |
Meyer, TE | 1 |
Adnams, C | 1 |
Commerford, P | 1 |
Bardenheuer, HJ | 1 |
Fabry, A | 1 |
Höfling, B | 1 |
Peter, K | 1 |
Martsevich, SY | 1 |
Koutishenko, N | 1 |
Trubel, W | 1 |
Moritz, A | 1 |
Laczkovics, A | 1 |
Haider, W | 1 |
Bullon, P | 3 |
Machuca, G | 3 |
Martinez-Sahuquillo, A | 2 |
Rios, JV | 2 |
Rojas, J | 2 |
Lacalle, JR | 2 |
Knyshov, GV | 1 |
Vykhovaniuk, IV | 1 |
Tkhor, NV | 1 |
Furkalo, SN | 1 |
Korchinskaia, OI | 1 |
Shalev, Y | 1 |
Ben-Hur, H | 1 |
Hagay, Z | 1 |
Blickstein, I | 1 |
Epstein, M | 1 |
Ayzenberg, O | 1 |
Gelven, A | 1 |
Caspi, A | 1 |
Lee, DD | 1 |
Rigonan, K | 1 |
Dequattro, V | 1 |
Moiseev, VS | 1 |
Shatkovskiĭ, NP | 1 |
Cheltsov, VV | 1 |
Ikram, H | 1 |
Low, CJ | 1 |
Shirlaw, TM | 1 |
Foy, SG | 1 |
Crozier, IG | 1 |
Richards, AM | 1 |
Khurmi, NS | 1 |
Horsburgh, RJ | 1 |
Andrews, TC | 3 |
Fenton, T | 2 |
Toyosaki, N | 1 |
Glasser, SP | 3 |
Young, PM | 2 |
MacCallum, G | 3 |
Gibson, RS | 1 |
Shook, TL | 2 |
Pupita, G | 1 |
Mazzara, D | 1 |
Centanni, M | 1 |
Rimatori, C | 1 |
Ferretti, GF | 1 |
Dessì-Fulgheri, P | 1 |
Russo, P | 1 |
Rappelli, A | 1 |
Lombardi, M | 1 |
Morales, MA | 1 |
Michelassi, C | 1 |
Moscarelli, E | 1 |
Distante, A | 1 |
L'Abbate, A | 1 |
Umeda, M | 1 |
Saida, K | 1 |
Molinero De Miguel, E | 1 |
Salcedo Arruti, A | 1 |
Sagastagoitia Gorostiza, JD | 1 |
Iriarte Ezkurdia, MM | 1 |
Fernandez Vidal, P | 1 |
Velasco Quintana, J | 1 |
Garrido García, J | 1 |
Egstrup, K | 1 |
Andersen, PE | 1 |
Iriarte, M | 1 |
Molinero, E | 1 |
Sagastagoitia, JD | 1 |
Arzubiaga, J | 1 |
Aguirre, J | 1 |
Salcedo, A | 1 |
Mauser, M | 1 |
Voelker, W | 1 |
Ickrath, O | 1 |
Karsch, KR | 1 |
Borzak, S | 1 |
Kato, M | 1 |
Nakashima, Y | 2 |
Levine, J | 1 |
Goldiner, PL | 1 |
Oka, Y | 1 |
Beevers, DG | 1 |
Sleight, P | 1 |
Tiefenbacher, CP | 1 |
Zimmermann, R | 1 |
Parekh, N | 1 |
Amann, K | 1 |
Tillmanns, H | 1 |
Rauch, B | 1 |
Kübler, W | 1 |
Pratt, CM | 1 |
Goldstein, S | 1 |
Dyrda, I | 1 |
Frishman, WH | 1 |
Hill, JA | 1 |
Morgan, NA | 1 |
Conti, CR | 3 |
Rayo Llerena, I | 1 |
Marín Huerta, E | 1 |
Cohen, JD | 1 |
Pomar Domingo, F | 1 |
Cosín Aguilar, J | 1 |
Hernándiz, A | 1 |
Portoles, M | 1 |
Pallarés, V | 1 |
Andrés, F | 1 |
Boström, PA | 1 |
Mansour, P | 1 |
Diemer, H | 1 |
Mattiasson, I | 1 |
Nehoum, A | 1 |
Lilja, B | 1 |
Berglund, G | 1 |
Filep, JG | 1 |
Skrobik, Y | 1 |
Fournier, A | 1 |
Földes-Filep, E | 1 |
Takahashi, T | 1 |
Takahashi, K | 1 |
Kishi-Tanikawa, S | 1 |
Tsuchida, K | 1 |
Araki, H | 1 |
Higuchi, S | 1 |
Cheng, DC | 1 |
Jiang, MT | 1 |
Asokumar, B | 1 |
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Sandler, A | 1 |
Velasco, E | 1 |
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Stason, W | 1 |
Schmid, CH | 1 |
Caubet, JF | 1 |
Kupelnick, B | 1 |
Cory, D | 1 |
Whiting, G | 1 |
Chalmers, TC | 1 |
Ross, SD | 1 |
Kobusiewicz, W | 1 |
Ogonowska-Kobusiewicz, M | 1 |
Michalak, J | 1 |
Ledwozyw, A | 1 |
Killip, T | 1 |
Forman, S | 1 |
Geller, N | 1 |
Deanfield, J | 1 |
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Yamamoto, A | 1 |
Ishikawa, Y | 1 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
[NCT00000478] | Phase 3 | 0 participants | Interventional | 1990-11-30 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
10 reviews available for nifedipine and Myocardial Ischemia
Article | Year |
---|---|
[Ischemic heart disease combined with hypertension: peculiarities of course and selection of therapy].
Topics: Adrenergic beta-Antagonists; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive | 2005 |
[Indications for calcium channel antagonist therapy according to the latest large clinical trials].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Antihypertensive Agents; Calcium Channel Blockers; Cli | 2005 |
Nifedipine. Dose-related increase in mortality in patients with coronary heart disease.
Topics: Angina Pectoris; Arrhythmias, Cardiac; Calcium Channel Blockers; Confidence Intervals; Coronary Dise | 1995 |
Short acting dihydropyridine (vasodilating) calcium channel blockers for hypertension: is there a risk?
Topics: Calcium Channel Blockers; Case-Control Studies; Clinical Trials as Topic; Dihydropyridines; Humans; | 1996 |
[Silent myocardial ischemia. Arguments against treatment].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Angina, Unstable; Atenolol; Bisoprolol; Calcium Channe | 1996 |
1995: the year of the calcium antagonist controversy.
Topics: Calcium Channel Blockers; Humans; Hypertension; Myocardial Infarction; Myocardial Ischemia; Nifedipi | 1996 |
Searching for signals: mortality and cardiovascular events in published randomized control trials of nifedipine in ischemic heart disease and hypertension.
Topics: Humans; Hypertension; Myocardial Ischemia; Nifedipine; Randomized Controlled Trials as Topic; Vasodi | 1996 |
[Nifedipine in ischemic heart disease: a ban on its use or a differential approach to therapy?].
Topics: Calcium Channel Blockers; Drug Tolerance; Humans; Myocardial Ischemia; Nifedipine; Safety | 1996 |
Calcium channel blockers for hypertension: dissecting the evidence for adverse effects.
Topics: Calcium Channel Blockers; Catecholamines; Cerebrovascular Disorders; Drug Evaluation; Gastrointestin | 1997 |
Circadian heart rate response to chronotherapy versus conventional therapy in patients with hypertension and myocardial ischemia.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Amlodipine; Atenolol; Blood Pressure; C | 2000 |
39 trials available for nifedipine and Myocardial Ischemia
Article | Year |
---|---|
Myocardial ischaemia in patients with impaired left ventricular function undergoing coronary artery bypass grafting--milrinone versus nifedipin.
Topics: Aged; Anesthesia, General; Calcium Channel Blockers; Coronary Artery Bypass; Coronary Disease; Creat | 2002 |
Comparison of perioperative myocardial protection with nifedipine versus nifedipine and metoprolol in patients undergoing elective coronary artery bypass grafting.
Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Artery Bypass; | 1995 |
Effect of isradipine and nifedipine on diastolic function in patients with left ventricular dysfunction due to coronary artery disease: a randomized, double-blind, nuclear, stethoscope study.
Topics: Adult; Aged; Angina Pectoris; Atrial Function, Right; Cardiac Pacing, Artificial; Diastole; Double-B | 1994 |
[The comparative efficacy of verapamil, nifedipine and propranolol in patients with IHD and an enhanced risk of a fatal outcome].
Topics: Adult; Cardiac Complexes, Premature; Electrocardiography, Ambulatory; Exercise Tolerance; Humans; Ma | 1994 |
Perioperative infusion of nifedipine and metoprolol provides antiischemic and antiarrhythmic protection in patients undergoing elective aortocoronary by-pass surgery.
Topics: Arrhythmias, Cardiac; Coronary Artery Bypass; Creatine Kinase; Electrocardiography, Ambulatory; Enda | 1994 |
Medical treatment to reduce total ischemic burden: total ischemic burden bisoprolol study (TIBBS), a multicenter trial comparing bisoprolol and nifedipine. The TIBBS Investigators.
Topics: Adult; Aged; Angina Pectoris; Bisoprolol; Double-Blind Method; Electrocardiography, Ambulatory; Euro | 1995 |
The Asymptomatic Cardiac Ischemia Pilot (ACIP) study: design of a randomized clinical trial, baseline data and implications for a long-term outcome trial.
Topics: Aged; Angina Pectoris; Atenolol; Diltiazem; Drug Therapy, Combination; Female; Humans; Isosorbide Di | 1994 |
Effects of treatment strategies to suppress ischemia in patients with coronary artery disease: 12-week results of the Asymptomatic Cardiac Ischemia Pilot (ACIP) study.
Topics: Aged; Atenolol; Coronary Disease; Diltiazem; Drug Therapy, Combination; Female; Humans; Isosorbide D | 1994 |
Comparison of the efficacy of atenolol and its combination with slow-release nifedipine in chronic stable angina.
Topics: Angina Pectoris; Atenolol; Blood Pressure; Chronic Disease; Delayed-Action Preparations; Double-Blin | 1993 |
Cardioprotection by nifedipine cardioplegia during coronary artery surgery.
Topics: Arrhythmias, Cardiac; Bicarbonates; Calcium Chloride; Cardiac Output; Cardiac Output, Low; Cardiople | 1994 |
Increased blood pressure and neural tone in the silent ischemia of hypertension: disparate effects of immediate release nifedipine.
Topics: Activities of Daily Living; Adult; Aged; Angina Pectoris; Blood Pressure; Circadian Rhythm; Echocard | 1993 |
[Differential use of vasodilators in various types of cardiac insufficiency].
Topics: Adult; Aged; Blood Pressure; Captopril; Cardiomyopathy, Dilated; Female; Humans; Hypertension; Male; | 1993 |
Angiotensin converting enzyme inhibition in chronic stable angina: effects on myocardial ischaemia and comparison with nifedipine.
Topics: Adult; Aged; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Chronic Diseas | 1994 |
Subsets of ambulatory myocardial ischemia based on heart rate activity. Circadian distribution and response to anti-ischemic medication. The Angina and Silent Ischemia Study Group (ASIS)
Topics: Circadian Rhythm; Diltiazem; Double-Blind Method; Electrocardiography, Ambulatory; Female; Heart Rat | 1993 |
Ischemia in collateral-dependent myocardium: effects of nifedipine and diltiazem in man.
Topics: Aged; Blood Pressure; Collateral Circulation; Coronary Disease; Diltiazem; Electrocardiography; Exer | 1993 |
Efficacy of isosorbide-5-mononitrate versus nifedipine in preventing spontaneous and ergonovine-induced myocardial ischaemia. A double-blind, placebo-controlled study.
Topics: Administration, Oral; Adult; Angina Pectoris, Variant; Double-Blind Method; Echocardiography; Electr | 1993 |
Comparative study of gallopamil versus nifedipine in patients with ischemic heart disease.
Topics: Adult; Aged; Analysis of Variance; Blood Pressure; Double-Blind Method; Electrocardiography; Exercis | 1993 |
Combined perioperative infusion of nifedipine and metoprolol provides antiischemic and antiarrhythmic protection in patients undergoing elective aortocoronary bypass surgery.
Topics: Aged; Arrhythmias, Cardiac; Coronary Artery Bypass; Drug Therapy, Combination; Electrocardiography, | 1993 |
Transient myocardial ischemia during nifedipine therapy in stable angina pectoris, and its relation to coronary collateral flow and comparison with metoprolol.
Topics: Angina Pectoris; Collateral Circulation; Coronary Angiography; Coronary Circulation; Double-Blind Me | 1993 |
Usefulness of exercise testing performed with vasodilators for predicting the severity of myocardial ischaemia during daily activities and treatment.
Topics: Activities of Daily Living; Adult; Angina Pectoris; Coronary Circulation; Coronary Disease; Drug The | 1993 |
[Comparison of the cardiodepressive effects of nifedipine, isradipine, nisoldipine and felodipine in patients with coronary heart disease].
Topics: Adult; Aged; Calcium Channel Blockers; Coronary Disease; Electrocardiography; Exercise Test; Felodip | 1993 |
Discordance between effects of anti-ischemic therapy on ambulatory ischemia, exercise performance and anginal symptoms in patients with stable angina pectoris. The Angina and Silent Ischemia Study Group (ASIS).
Topics: Aged; Angina Pectoris; Diltiazem; Double-Blind Method; Electrocardiography, Ambulatory; Exercise Tes | 1993 |
Comparison of subgroups assigned to medical regimens used to suppress cardiac ischemia (the Asymptomatic Cardiac Ischemia Pilot [ACIP] Study).
Topics: Angina Pectoris; Atenolol; Case-Control Studies; Delayed-Action Preparations; Diltiazem; Drug Therap | 1996 |
Prognostic significance of transient ischemic episodes: response to treatment shows improved prognosis. Results of the Total Ischemic Burden Bisoprolol Study (TIBBs) follow-up.
Topics: Adrenergic beta-Antagonists; Bisoprolol; Calcium Channel Blockers; Delayed-Action Preparations; Dise | 1996 |
Asymptomatic Cardiac Ischemia Pilot (ACIP) study two-year follow-up: outcomes of patients randomized to initial strategies of medical therapy versus revascularization.
Topics: Adrenergic beta-Antagonists; Aged; Angioplasty, Balloon, Coronary; Atenolol; Calcium Channel Blocker | 1997 |
[Effectiveness and tolerability of bisoprolol vs. nifedipine in uremic patients with ischemic cardiopathy in dialysis treatment].
Topics: Adrenergic beta-Antagonists; Bisoprolol; Calcium Channel Blockers; Female; Humans; Male; Middle Aged | 1997 |
Relationship between calcium channel antagonists and nocturnal hypotension and autonomic imbalance in patients with a previous myocardial infarction.
Topics: Adult; Aged; Angina Pectoris; Autonomic Nervous System; Blood Pressure; Blood Pressure Monitoring, A | 1998 |
Effects of therapy with nifedipine GITS or atenolol on mental stress-induced ischemic left ventricular dysfunction.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Cross-Over Studies; Diastole; Double-Blind Metho | 1998 |
Heart rate variability and ischaemia in patients with coronary heart disease and stable angina pectoris; influence of drug therapy and prognostic value. TIBBS Investigators Group. Total Ischemic Burden Bisoprolol Study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Bisoprolol; Calcium Channel Blockers; Cir | 1999 |
Effects of a slow-release nifedipine on 24-hour ambulatory blood pressure and ischemic changes on 24-hour ambulatory electrocardiogram in patients with severe coronary artery disease.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Blood Pressure Monitoring, Ambulatory; Calcium Channe | 2000 |
[Clinical study on relationship among Heart-Qi Deficiency, left ventricular function and myocardial ischemia in patients with coronary heart disease].
Topics: Aged; Angina Pectoris; Drugs, Chinese Herbal; Female; Humans; Male; Middle Aged; Myocardial Contract | 1998 |
[Efficacy of OSMO-Adalat in patients with arterial hypertension in combination with kinked precerebral arteries].
Topics: Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Carotid Artery Diseases; De | 2001 |
Effects of nifedipine retard on heart rate and autonomic balance in patients with ischemic heart disease.
Topics: Aged; Autonomic Nervous System; Calcium Channel Blockers; Circadian Rhythm; Delayed-Action Preparati | 2001 |
Comparison of negative inotropic and vasodilator effects of isradipine and nifedipine after complete autonomic blockade in ischemic heart disease.
Topics: Autonomic Nerve Block; Depression, Chemical; Double-Blind Method; Heart Rate; Hemodynamics; Humans; | 1992 |
Effects of nifedipine and diltiazem on myocardial ischemia in patients with severe stable angina pectoris treated with nitrates and beta-blockers.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Diltiazem; Double-Blind Method; Electroca | 1992 |
[Effect of various antianginal agents on the frequency and duration of myocardial ischemic episodes in patients with stable angina pectoris].
Topics: Angina Pectoris; Drug Therapy, Combination; Humans; Myocardial Ischemia; Nifedipine; Periodicity; Pr | 1992 |
[The anti-ischemic effect of gallopamil-retard in comparison with nifedipine-retard in stable angina pectoris].
Topics: Aged; Angina Pectoris; Blood Pressure; Coronary Disease; Delayed-Action Preparations; Dose-Response | 1992 |
Intravenous nifedipine for prevention of myocardial ischaemia after coronary revascularization.
Topics: Blood Pressure; Coronary Artery Bypass; Creatine Kinase; Electrocardiography; Electrocardiography, A | 1992 |
Clinical investigation of asymptomatic cardiac ischemia.
Topics: Angina Pectoris; Angioplasty, Balloon, Coronary; Atenolol; Coronary Artery Bypass; Coronary Disease; | 1991 |
55 other studies available for nifedipine and Myocardial Ischemia
Article | Year |
---|---|
Direct cardiac toxicity of the tentacle-only extract from the jellyfish Cyanea capillata demonstrated in isolated rat heart.
Topics: Animals; Calcium Channels, L-Type; Cnidarian Venoms; Coronary Vasospasm; Dose-Response Relationship, | 2012 |
Glycidipine, a promising hypotensive and cardioprotective agent.
Topics: Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Cardiotonic Agents; Drug Combinations; Dru | 2011 |
[Broadened indications for the use of selective β-adrenoblockers].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Bisoprolol; Calcium Channel Blockers; Female; | 2012 |
Expression of the nuclear factor-kappaB and proto-oncogenes c-fos and c-jun are induced by low extracellular Mg2+ in aortic and cerebral vascular smooth muscle cells: possible links to hypertension, atherogenesis, and stroke.
Topics: Animals; Aorta, Thoracic; Biomarkers; Calcium; Calcium Channel Blockers; Cardiovascular Diseases; Di | 2003 |
Spontaneous activity induced in rabbit Purkinje myocytes during coupling to a depolarized model cell.
Topics: Action Potentials; Animals; Cadmium; Coculture Techniques; Gap Junctions; Heart Ventricles; Lithium; | 2003 |
Negative inotropic drugs alter indexes of cytosolic [Ca(2+)]-left ventricular pressure relationships after ischemia.
Topics: Animals; Benzopyrans; Calcium; Calcium Channel Blockers; Cardiotonic Agents; Cytosol; Diacetyl; Dihy | 2004 |
Reversible left ventricular hypertrophy after tako-tsubo-like cardiomyopathy.
Topics: Aged; Aspirin; Benzimidazoles; Biphenyl Compounds; Cardiomyopathy, Dilated; Chest Pain; Drug Therapy | 2005 |
The effect of ionizing radiation of 1,4-dihydropyridine derivatives in the solid state.
Topics: Calcium Channel Blockers; Dihydropyridines; Electron Spin Resonance Spectroscopy; Felodipine; Gamma | 2007 |
Effects of nifedipine on systemic and pulmonary vascular impedance in subjects undergoing cardiac catheterization.
Topics: Administration, Sublingual; Adult; Algorithms; Calcium Channel Blockers; Cardiac Catheterization; Ca | 2006 |
Hemodynamic and antiischemic effects of nifedipine, lacidipine, and nisoldipine in rat isolated working heart.
Topics: Animals; Calcium Channel Blockers; Cardiac Output; Coronary Circulation; Dihydropyridines; Dose-Resp | 1993 |
Antiischemic effects of nifedipine in isolated working heart preparations of healthy, diabetic, and hypertensive rats.
Topics: Animals; Blood Glucose; Blood Pressure; Body Weight; Cardiac Output; Coronary Circulation; Diabetes | 1994 |
[The nifedipine withdrawal syndrome in patients with stable stenocardia of effort].
Topics: Angina Pectoris; Electrocardiography; Exercise Test; Exercise Tolerance; Humans; Myocardial Ischemia | 1995 |
Cardioprotection by nifedipine in isolated working hearts: a comparative study on three different types of experimental ischemia.
Topics: Animals; Cardiac Output; Coronary Circulation; Dimethyl Sulfoxide; Electric Stimulation; Heart; Male | 1993 |
[The preoperative drug correction of disorders in myocardial functional reserve in patients with ischemic heart disease].
Topics: Adult; Amiodarone; Combined Modality Therapy; Coronary Artery Bypass; Drug Therapy, Combination; Hea | 1994 |
[Effect of nifedipine on T wave in ischemic myocardium].
Topics: Adenosine; Animals; Electrocardiography; Female; Male; Myocardial Ischemia; Nifedipine; Swine | 1994 |
Comparative examination of Adalat and Cordaflex in anti-ischaemic therapy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Drug Evaluation; Drug Therapy, Combination; Electrocardiog | 1993 |
Adenosine: a sensitive marker of myocardial ischaemia in man.
Topics: Adenosine; Aged; Angioplasty, Balloon, Coronary; Biomarkers; Coronary Circulation; Coronary Disease; | 1994 |
Withdrawal phenomenon after abrupt cessation of nifedipine in stable angina pectoris.
Topics: Angina Pectoris; Exercise Test; Exercise Tolerance; Humans; Male; Middle Aged; Myocardial Ischemia; | 1993 |
Clinical assessment of gingival hyperplasia in patients treated with nifedipine.
Topics: Dental Plaque Index; Dose-Response Relationship, Drug; Female; Gingival Hemorrhage; Gingival Hyperpl | 1994 |
[Hemodynamic basis of antianginal effect of calcium antagonists in patients with ischemic heart disease after aortocoronary shunting: myocardial reserve potentials and their mechanisms].
Topics: Adult; Angina Pectoris; Coronary Artery Bypass; Dose-Response Relationship, Drug; Exercise Test; Hem | 1993 |
Successful delivery following myocardial ischemia during the second trimester of pregnancy.
Topics: Acute Disease; Adult; Atenolol; Cardiac Catheterization; Coronary Angiography; Female; Heparin; Huma | 1993 |
Improvement of ischemic myocardial dysfunction by nisoldipine in relation to its coronary vasodilating action.
Topics: Animals; Blood Pressure; Coronary Circulation; Diltiazem; Heart Rate; In Vitro Techniques; Male; Myo | 1993 |
Does transesophageal echocardiography improve postoperative outcome in patients undergoing coronary artery bypass surgery?
Topics: Adult; Aged; Aged, 80 and over; Blood Pressure; Cardiac Output; Coronary Artery Bypass; Creatine Kin | 1993 |
Preservation of myocardial blood flow by calcium antagonists does not prevent attenuation of regional myocardial function after repetitive brief periods of myocardial ischaemia in the rat heart.
Topics: Animals; Blood Flow Velocity; Calcium Channel Blockers; Female; Gallopamil; Infusions, Intravenous; | 1995 |
[Effects of nitroglycerin and nifedipine on stunned myocardium due to brief repeated ischemias].
Topics: Analysis of Variance; Animals; Calcium Channel Blockers; Data Interpretation, Statistical; Dogs; Ele | 1996 |
Blood pressure and myocardial perfusion in hypertensive patients with and without left ventricular hypertrophy.
Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Captopril; Coron | 1995 |
Effects of calcium antagonists on endothelin-1-induced myocardial ischaemia and oedema in the rat.
Topics: Albumins; Animals; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Edema | 1996 |
Effects of a new calcium antagonist, CD-832, on isoproterenol-induced myocardial ischemia in dogs with partial coronary stenosis.
Topics: Angina Pectoris; Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Diltiaze | 1996 |
Comparison of nifedipine and metoprolol on collateral coronary blood flow in a swine model of chronic coronary obstruction and acute ischaemia during isoflurane anaesthesia.
Topics: Adrenergic beta-Antagonists; Anesthetics, Inhalation; Animals; Calcium Channel Blockers; Chronic Dis | 1996 |
Evaluation of gingival and periodontal conditions following causal periodontal treatment in patients treated with nifedipine and diltiazem.
Topics: Analysis of Variance; Calcium Channel Blockers; Chi-Square Distribution; Dental Care for Chronically | 1996 |
Calcium channel blocker debate: true lies?
Topics: Angina Pectoris; Calcium Channel Blockers; Humans; Hypertension; Myocardial Contraction; Myocardial | 1996 |
The influence of nifedipine and verapamil on the ischaemia-induced changes in canine sarcolemmal membranes.
Topics: Animals; Calcium Channel Blockers; Calcium-Transporting ATPases; Cell Membrane; Dog Diseases; Dogs; | 1995 |
Silent myocardial ischemia: some good news.
Topics: Adrenergic beta-Antagonists; Atenolol; Calcium Channel Blockers; Combined Modality Therapy; Coronary | 1997 |
Effect of efonidipine, a novel dihydropyridine derivative, on myocardial metabolic changes induced by coronary artery ligation in dogs: comparison with nifedipine.
Topics: Animals; Calcium Channel Blockers; Carbohydrate Metabolism; Dihydropyridines; Dogs; Energy Metabolis | 1997 |
Antianginal effects of YM430, a novel calcium entry-blocking and beta-adrenoceptor-blocking agent in several experimental angina models.
Topics: 4-Aminopyridine; Adrenergic beta-Antagonists; Amifampridine; Angina Pectoris; Animals; Calcium Chann | 1997 |
[The use of Cordanum in combination with Corinfar-Retard for the treatment of ectopic arrhythmias in the sick sinus syndrome in patients with ischemic heart disease].
Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Delayed-Action Preparations; Drug Evaluat | 1997 |
Differential roles of myocardial Ca2+ channels and Na+/Ca2+ exchange in myocardial reperfusion injury in open chest dogs: relative roles during ischemia and reperfusion.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1997 |
A potential risk of sublingual nifedipine treatment in surgically treated patients in Japan.
Topics: Administration, Sublingual; Calcium Channel Blockers; Clinical Competence; Humans; Japan; Myocardial | 1998 |
[Adalat effects on clinical course of coronary heart disease, peripheral circulation and myocardial perfusion in patients with stenosing coronary atherosclerosis].
Topics: Adult; Blood Flow Velocity; Calcium Channel Blockers; Coronary Artery Disease; Coronary Circulation; | 1998 |
[A 73-year-old patient with hypertensive crisis. Was the use of calcium antagonist nifedipine justified?].
Topics: Aged; Antihypertensive Agents; Calcium Channel Blockers; Drug Therapy, Combination; Electrocardiogra | 1999 |
Temporal differences in actions of calcium channel blockers on K+ accumulation, cardiac function, and high-energy phosphate levels in ischemic guinea pig hearts.
Topics: Acidosis; Adenosine Triphosphate; Animals; Calcium Channel Blockers; Depression, Chemical; Diltiazem | 1999 |
Role of protein kinase C in mitochondrial KATP channel-mediated protection against Ca2+ overload injury in rat myocardium.
Topics: Adenosine Triphosphate; Alkaloids; Animals; Benzophenanthridines; Calcium; Calcium Channel Blockers; | 1999 |
Effects of nifedipine on myocardial blood flow and systolic function in humans with ischemic heart disease.
Topics: Aged; Blood Flow Velocity; Coronary Circulation; Female; Humans; Male; Middle Aged; Myocardial Ische | 1999 |
Effect of Ca2+ channel blockers on arterial hypertension and heart ischaemic lesions induced by chronic blockade of nitric oxide in the rat.
Topics: Animals; Blood Pressure; Blood Pressure Determination; Body Weight; Calcium Channel Blockers; Diltia | 1999 |
Low-dose calcium antagonists reduce energy demand and cellular damage of isolated hearts during both ischemia and reperfusion.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Coronary Circulation; Diltiazem; Dose-Response Relati | 1999 |
Nifedipine-induced coronary vasodilation in ischemic hearts is attributable to bradykinin- and NO-dependent mechanisms in dogs.
Topics: Animals; Bradykinin; Calcium Channel Blockers; Coronary Vessels; Cyclic GMP; Dogs; Heart Rate; Myoca | 2000 |
Effects of different vasodilators on human internal mammary artery in vitro.
Topics: Ethanolamines; Female; Humans; In Vitro Techniques; Isoproterenol; Isosorbide Dinitrate; Male; Mamma | 1999 |
The protein kinase inhibitor fasudil protects against ischemic myocardial injury induced by endothelin-1 in the rabbit.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Movement; Diltiazem; Electrocardiograph | 2000 |
Protective effect of diltiazem against ischemia-induced decreases in regional myocardial flow in rat heart.
Topics: Animals; Calcium Channel Blockers; Cardiovascular Agents; Coronary Circulation; Diltiazem; Heart; He | 2000 |
Energy preserving effect of l-cis diltiazem in isolated ischemic and reperfused guinea pig hearts: a 31P-NMR study.
Topics: Adenosine Triphosphate; Animals; Calcium Channel Blockers; Diltiazem; Guinea Pigs; Heart; Hydrogen-I | 2000 |
The gingival inflammatory infiltrate in cardiac patients treated with calcium antagonists.
Topics: Analysis of Variance; Calcium Channel Blockers; Case-Control Studies; Chi-Square Distribution; Dilti | 2001 |
Cardioprotective effects of 9-hydroxyellipticine on ischemia and reperfusion in isolated rat heart.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Binding, Competitive; Calcium; CHO Cells; Cri | 2002 |
[The effect of nitrosorbide, korinfar, obzidan and spesikor on cardiovascular function in a right bundle of His block].
Topics: Adult; Anti-Arrhythmia Agents; Bundle-Branch Block; Cardiovascular System; Drug Evaluation; Electroc | 1992 |
[Correlation of antianginal effect of corinfar and diastolic function in patients with ischemic heart disease].
Topics: Diastole; Humans; Male; Middle Aged; Myocardial Ischemia; Nifedipine; Ventricular Function, Left | 1992 |
[ Combined therapy with isosorbide dinitrate, propranolol and nifedipine in patients with chronic ischemic heart disease].
Topics: Adult; Aged; Angina Pectoris; Chronic Disease; Drug Therapy, Combination; Heart Rate; Hemodynamics; | 1992 |