nifedipine has been researched along with Muscular Dystrophy, Duchenne in 3 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Muscular Dystrophy, Duchenne: An X-linked recessive muscle disease caused by an inability to synthesize DYSTROPHIN, which is involved with maintaining the integrity of the sarcolemma. Muscle fibers undergo a process that features degeneration and regeneration. Clinical manifestations include proximal weakness in the first few years of life, pseudohypertrophy, cardiomyopathy (see MYOCARDIAL DISEASES), and an increased incidence of impaired mentation. Becker muscular dystrophy is a closely related condition featuring a later onset of disease (usually adolescence) and a slowly progressive course. (Adams et al., Principles of Neurology, 6th ed, p1415)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Search terms were 'calcium antagonists' or 'calcium channel blocker' or 'dantrolene' or 'verapamil' or 'nifedipine' or 'flunarizine' or 'diltiazem' or 'amlodipine' or 'nicardipine' and 'Muscular Dystrophy, Duchenne'." | 4.84 | Calcium antagonists for Duchenne muscular dystrophy. ( Phillips, MF; Quinlivan, R, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Harisseh, R | 1 |
| Chatelier, A | 1 |
| Magaud, C | 1 |
| Déliot, N | 1 |
| Constantin, B | 1 |
| Altamirano, F | 1 |
| Valladares, D | 1 |
| Henríquez-Olguín, C | 1 |
| Casas, M | 1 |
| López, JR | 1 |
| Allen, PD | 1 |
| Jaimovich, E | 1 |
| Phillips, MF | 1 |
| Quinlivan, R | 1 |
1 review available for nifedipine and Muscular Dystrophy, Duchenne
| Article | Year |
|---|---|
Calcium antagonists for Duchenne muscular dystrophy.
Topics: Calcium Channel Blockers; Diltiazem; Flunarizine; Humans; Muscle Strength; Muscle, Skeletal; Muscula | 2008 |
2 other studies available for nifedipine and Muscular Dystrophy, Duchenne
| Article | Year |
|---|---|
Involvement of TRPV2 and SOCE in calcium influx disorder in DMD primary human myotubes with a specific contribution of α1-syntrophin and PLC/PKC in SOCE regulation.
Topics: Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Calcium-Binding Proteins; Cells, Cult | 2013 |
Nifedipine treatment reduces resting calcium concentration, oxidative and apoptotic gene expression, and improves muscle function in dystrophic mdx mice.
Topics: Animals; Calcium; Cells, Cultured; Creatine Kinase; Male; Mice; Mice, Inbred mdx; Muscle Strength; M | 2013 |