Page last updated: 2024-11-01

nifedipine and Muscular Dystrophies

nifedipine has been researched along with Muscular Dystrophies in 11 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Muscular Dystrophies: A heterogeneous group of inherited MYOPATHIES, characterized by wasting and weakness of the SKELETAL MUSCLE. They are categorized by the sites of MUSCLE WEAKNESS; AGE OF ONSET; and INHERITANCE PATTERNS.

Research Excerpts

ExcerptRelevanceReference
"Properties of nitrendipine receptors have been analyzed in skeletal muscle from normal young boys and boys with Duchenne muscular dystrophy (DMD)."7.67[3H]nitrendipine receptors as markers of a class of putative voltage-sensitive Ca2+ channels in normal human skeletal muscle and in muscle from Duchenne muscular dystrophy patients. ( Delpont, E; Desnuelle, C; Lazdunski, M; Renaud, JF; Serratrice, G, 1986)
"Properties of nitrendipine receptors have been analyzed in skeletal muscle from normal young boys and boys with Duchenne muscular dystrophy (DMD)."3.67[3H]nitrendipine receptors as markers of a class of putative voltage-sensitive Ca2+ channels in normal human skeletal muscle and in muscle from Duchenne muscular dystrophy patients. ( Delpont, E; Desnuelle, C; Lazdunski, M; Renaud, JF; Serratrice, G, 1986)
" At a dosage of 20 mg/kg/day, drug therapy in each case significantly prolonged the functional ability of the dystrophic chickens as quantitated regularly by a standardized test for righting ability."1.27In vivo effects of three calcium blockers on chickens with inherited muscular dystrophy. ( Heffner, RR; Hudecki, MS; Pollina, CM, 1984)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19907 (63.64)18.7374
1990's3 (27.27)18.2507
2000's1 (9.09)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Svetoni, N1
Spargi, T1
Bellantonio, M1
Lanzetta, T1
Hudecki, MS1
Pollina, CM1
Heffner, RR1
Bach, PR1
Benders, AA2
Wevers, RA2
Veerkamp, JH2
Mulè, F1
Serio, R1
Fong, PY1
Turner, PR1
Denetclaw, WF1
Steinhardt, RA1
Jacobs, AE1
Oosterhof, A1
van Mier, P1
Joosten, EM1
Desnuelle, C1
Renaud, JF1
Delpont, E1
Serratrice, G1
Lazdunski, M1
Bretag, AH1
Moxley, RT2
Brooke, MH1
Fenichel, GM1
Mendell, JR1
Griggs, RC1
Miller, JP1
Province, MA1
Patterson, V1

Trials

1 trial available for nifedipine and Muscular Dystrophies

ArticleYear
Clinical investigation in Duchenne dystrophy. VI. Double-blind controlled trial of nifedipine.
    Muscle & nerve, 1987, Volume: 10, Issue:1

    Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Contracture; Creatine Kinase;

1987

Other Studies

10 other studies available for nifedipine and Muscular Dystrophies

ArticleYear
[Erb's muscular dystrophy and congestive myocardiopathy. Description of a case with a whoop due to tricuspid insufficiency].
    Giornale italiano di cardiologia, 1984, Volume: 14, Issue:1

    Topics: Adult; Cardiomyopathy, Dilated; Heart Auscultation; Heart Failure; Heart Murmurs; Humans; Male; Musc

1984
In vivo effects of three calcium blockers on chickens with inherited muscular dystrophy.
    Experimental neurology, 1984, Volume: 84, Issue:3

    Topics: Animals; Benzazepines; Calcium; Chickens; Creatine Kinase; Diltiazem; Disease Models, Animal; Female

1984
Determination of nifedipine in serum or plasma by reversed-phase liquid chromatography.
    Clinical chemistry, 1983, Volume: 29, Issue:7

    Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Humans; Muscular Dystrophies; Nifedipi

1983
Ion transport in human skeletal muscle cells: disturbances in myotonic dystrophy and Brody's disease.
    Acta physiologica Scandinavica, 1996, Volume: 156, Issue:3

    Topics: Acetylcholine; Adolescent; Adult; Biological Transport, Active; Calcium; Calcium Channel Blockers; C

1996
Increased calcium influx is responsible for the sustained mechanical tone in colon from dystrophic (mdx) mice.
    Gastroenterology, 2001, Volume: 120, Issue:6

    Topics: Animals; Calcium; Colon; Indoles; Male; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscle Contracti

2001
Increased activity of calcium leak channels in myotubes of Duchenne human and mdx mouse origin.
    Science (New York, N.Y.), 1990, Nov-02, Volume: 250, Issue:4981

    Topics: Animals; Calcium; Calcium Channels; Dystrophin; Humans; Membrane Potentials; Mice; Muscles; Muscular

1990
The calcium homeostasis and the membrane potential of cultured muscle cells from patients with myotonic dystrophy.
    Biochimica et biophysica acta, 1990, Nov-14, Volume: 1096, Issue:1

    Topics: Acetylcholine; Adult; Calcium; Calcium Channels; Cells, Cultured; Cytoplasm; Female; Homeostasis; Hu

1990
[3H]nitrendipine receptors as markers of a class of putative voltage-sensitive Ca2+ channels in normal human skeletal muscle and in muscle from Duchenne muscular dystrophy patients.
    Muscle & nerve, 1986, Volume: 9, Issue:2

    Topics: Calcium; Calcium Channels; Child; Child, Preschool; Humans; Ion Channels; Kinetics; Male; Muscles; M

1986
Nifedipine in the treatment of myotonia.
    Journal of neurology, neurosurgery, and psychiatry, 1988, Volume: 51, Issue:2

    Topics: Humans; Muscular Dystrophies; Myotonia; Nifedipine

1988
Absence of major side effects of nifedipine following treatment of Duchenne dystrophy.
    Pediatrics, 1985, Volume: 75, Issue:6

    Topics: Humans; Muscular Dystrophies; Nifedipine

1985