Page last updated: 2024-11-01

nifedipine and Muscle Spasm

nifedipine has been researched along with Muscle Spasm in 34 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Research Excerpts

ExcerptRelevanceReference
"We have used a placebo controlled trial to investigate the effect of long-term administration of nifedipine in the prevention of symptomatic episodes of oesophageal spasm."9.06Trial of nifedipine for prevention of oesophageal spasm. ( Davies, HA; Henderson, AH; Lewis, MJ; Rhodes, J, 1987)
"Although nifedipine therapy resulted in substantial relief of dysphagia in six patients with diffuse esophageal spasm, significant side effects, particularly in young working subjects, precluded prolonged use."7.67Nifedipine therapy for diffuse esophageal spasm. ( Morse, J; Thomas, E; Willis, M; Witt, P, 1986)
"We report clinical experience with the coronary vasodilator nifedipine in 127 patients with symptoms of myocardial ischemia associated with electrocardiographic or angiographic evidence, or both, of coronary-artery spasm."7.66Nifedipine therapy for coronary-artery spasm. Experience in 127 patients. ( Achuff, S; Antman, E; Braunwald, E; Geltman, E; Goldberg, S; Heupler, F; Kerin, NZ; Liang, CS; MacAlpin, R; Muller, J; Neff, RK; Reichek, N; Rubenfire, M; Tabatznik, B, 1980)
"In a patient with variant angina, we have shown that the calcium-channel blocker nifedipine inhibits both spontaneous and ergonivine-induced coronary artery spasm."7.66The angiographic effect of ergonovine and nifedipine in coronary artery spasm. ( Al-Sadir, J; Ford, LE; Rich, S, 1980)
" The sublingual adminstration of nifedipine reversed both the acute and the delayed cerebral arterial spasm."7.66Cerebral arterial spasm: part 10. Reversal of acute and chronic spasm in dogs with orally administered nifedipine. ( Allen, GS; Bahr, AL, 1979)
"Nifedipine was evaluated in the management of eight patients with intractable coronary arterial spasm."7.66Nifedipine therapy for refractory coronary arterial spasm. ( Heupler, FA; Proudfit, WL, 1979)
"We have used a placebo controlled trial to investigate the effect of long-term administration of nifedipine in the prevention of symptomatic episodes of oesophageal spasm."5.06Trial of nifedipine for prevention of oesophageal spasm. ( Davies, HA; Henderson, AH; Lewis, MJ; Rhodes, J, 1987)
" Nifedipine has proved effective in preventing coronary arterial spasm in patients with Prinzmetal's angina."4.76Inappropriate coronary vasoconstriction in patients with coronary artery disease: a role for nifedipine? ( Green, L; Grossman, W; Gunther, S; Mudge, GH; Muller, JE, 1979)
"Although nifedipine therapy resulted in substantial relief of dysphagia in six patients with diffuse esophageal spasm, significant side effects, particularly in young working subjects, precluded prolonged use."3.67Nifedipine therapy for diffuse esophageal spasm. ( Morse, J; Thomas, E; Willis, M; Witt, P, 1986)
"We report clinical experience with the coronary vasodilator nifedipine in 127 patients with symptoms of myocardial ischemia associated with electrocardiographic or angiographic evidence, or both, of coronary-artery spasm."3.66Nifedipine therapy for coronary-artery spasm. Experience in 127 patients. ( Achuff, S; Antman, E; Braunwald, E; Geltman, E; Goldberg, S; Heupler, F; Kerin, NZ; Liang, CS; MacAlpin, R; Muller, J; Neff, RK; Reichek, N; Rubenfire, M; Tabatznik, B, 1980)
"In a patient with variant angina, we have shown that the calcium-channel blocker nifedipine inhibits both spontaneous and ergonivine-induced coronary artery spasm."3.66The angiographic effect of ergonovine and nifedipine in coronary artery spasm. ( Al-Sadir, J; Ford, LE; Rich, S, 1980)
" The sublingual adminstration of nifedipine reversed both the acute and the delayed cerebral arterial spasm."3.66Cerebral arterial spasm: part 10. Reversal of acute and chronic spasm in dogs with orally administered nifedipine. ( Allen, GS; Bahr, AL, 1979)
"Nifedipine was evaluated in the management of eight patients with intractable coronary arterial spasm."3.66Nifedipine therapy for refractory coronary arterial spasm. ( Heupler, FA; Proudfit, WL, 1979)
"The clinical response to therapy with the calcium-blocking agent nifedipine was assessed in 12 patients with variant angina pectoris who were 44 to 67 years old."3.66Nifedipine in the treatment of Prinzmetal's (variant) angina. ( Goldberg, S; Hirshfeld, JW; Kastor, JA; Muller, J; Reichek, N; Wilson, J, 1979)
"Based on in vivo studies on isolated muscle strips of the LES and on manometric in vivo studies on 8 mongrel dogs, 6 healthy volunteers, 6 patients with achalasia and 3 subjects with diffuse esophageal spasm we could demonstrate that nifedipine causes a long-lasting relaxation of smooth muscle, the esophagus and LES."3.65[Clinical and experimental studies on the efficiency of nifedipine on smooth muscle strips of the esophagus (author's transl)]. ( Golenhofen, K; Lepsien, G; Schattenmann, G; Siewert, R; Weiser, HF, 1977)
"Acute hypocalcemia is generally caused by a sudden drop in serum calcium ion and presents with a mild or severe form of tetany."1.91Hypocalcemic tetany associated with simultaneous administration of cimetidine and nifedipine: a case report. ( Bezabhe, WM; Bezabih, YM; Bimrew, MA, 2023)
"Levcromakalim was much less potent (427 fold) against the spasm evoked by KCl (80 mM) than against the spasm evoked by oxytocin (0."1.29Cellular localization of the inhibitory action of relaxin against uterine spasm. ( Hollingsworth, M; Hughes, SJ, 1995)
"Treatment with nifedipine did not significantly change any of the pulmonary function values, except for the carbon monoxide diffusing capacity (DLCO)."1.28Diffusing capacity of the lung and nifedipine in systemic sclerosis. ( Georgiakodis, F; Kyriakidis, M; Papazoglou, S; Sfikakis, P; Sfikakis, PP; Toutouzas, P; Vergos, C, 1990)
"Coronary spasm is due to strong contraction of coronary vascular smooth muscle cells which is triggered by an increase of intracellular calcium ions; hyperventilation plus TRIS-buffer infusion induces coronary spasm by decreasing hydrogen ions which antagonize the action of calcium ions."1.26Pathophysiology and treatment of coronary arterial spasm. ( Yasue, H, 1980)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199024 (70.59)18.7374
1990's7 (20.59)18.2507
2000's2 (5.88)29.6817
2010's0 (0.00)24.3611
2020's1 (2.94)2.80

Authors

AuthorsStudies
Bezabih, YM1
Bimrew, MA1
Bezabhe, WM1
Garrison, CP1
Colman, N1
Wieling, W1
Wilde, AA1
Nasrallah, SM2
Beinart, C1
Sos, TA1
Saddekni, S1
Weiner, MA1
Sniderman, KW1
Kemerer, VF1
Dagher, FJ1
Pais, SO1
Bigot, A1
Moreau, D1
De Kersaint-Gilly, A1
Pinaud, M1
Antman, E1
Muller, J2
Goldberg, S2
MacAlpin, R1
Rubenfire, M1
Tabatznik, B1
Liang, CS1
Heupler, F1
Achuff, S1
Reichek, N2
Geltman, E1
Kerin, NZ1
Neff, RK1
Braunwald, E1
Yasue, H1
Heupler, FA2
Davies, HA2
Lewis, M1
Rhodes, J2
Henderson, A1
Rich, S1
Ford, LE1
Al-Sadir, J1
Halstead, LS1
Seager, SW1
Houston, JM1
Whitesell, K1
Dennis, M1
Nance, PW1
Winterkorn, JM1
Kupersmith, MJ1
Wirtschafter, JD1
Forman, S1
Hughes, SJ1
Hollingsworth, M1
Gunther, S1
Green, L1
Muller, JE1
Mudge, GH1
Grossman, W1
Allen, GS2
Banghart, SB1
Bahr, AL1
Lown, B1
Proudfit, WL1
Wilson, J1
Hirshfeld, JW1
Kastor, JA1
Kaltenbach, M1
Schulz, W1
Kober, G1
Proudfit, W1
Oliva, PB1
Pearle, DL1
Weiser, HF1
Lepsien, G1
Golenhofen, K1
Schattenmann, G1
Siewert, R1
Gabrielian, ES2
Akopov, SE2
Grigorian, GS1
Tunian, IuS1
Ghazarian, AV1
Sfikakis, PP1
Kyriakidis, M1
Vergos, C1
Papazoglou, S1
Georgiakodis, F1
Toutouzas, P1
Sfikakis, P1
Gasser, P1
Flammer, J1
Guthauser, U1
Mahler, F1
Geller, LI1
Petrenko, VF1
Lewis, MJ1
Henderson, AH1
Thomas, E1
Witt, P1
Willis, M1
Morse, J1
Tommaso, CL1
Singleton, RT1
Backhaus, EA1

Reviews

2 reviews available for nifedipine and Muscle Spasm

ArticleYear
Syndrome of symptomatic coronary arterial spasm with nearly normal coronary arteriograms.
    The American journal of cardiology, 1980, Volume: 45, Issue:4

    Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Coronary Angiography; Coronary Vessels; Electrocardiog

1980
Inappropriate coronary vasoconstriction in patients with coronary artery disease: a role for nifedipine?
    The American journal of cardiology, 1979, Oct-22, Volume: 44, Issue:5

    Topics: Angina Pectoris, Variant; Blood Pressure; Cardiac Catheterization; Cardiac Pacing, Artificial; Coron

1979

Trials

2 trials available for nifedipine and Muscle Spasm

ArticleYear
Trial of nifedipine for prevention of oesophageal spasm.
    Digestion, 1987, Volume: 36, Issue:2

    Topics: Adult; Double-Blind Method; Drug Evaluation; Esophageal Diseases; Female; Humans; Male; Middle Aged;

1987
Primary esophageal motor disorders: clinical response to nifedipine.
    Southern medical journal, 1985, Volume: 78, Issue:3

    Topics: Adult; Aged; Esophageal Achalasia; Esophageal Diseases; Esophagogastric Junction; Female; Humans; Ma

1985

Other Studies

30 other studies available for nifedipine and Muscle Spasm

ArticleYear
Hypocalcemic tetany associated with simultaneous administration of cimetidine and nifedipine: a case report.
    Journal of medical case reports, 2023, Jul-28, Volume: 17, Issue:1

    Topics: Calcium Gluconate; Cimetidine; Dyspepsia; Female; Humans; Hypocalcemia; Middle Aged; Nifedipine; Spa

2023
Nipple vasospasms, Raynaud's syndrome, and nifedipine.
    Journal of human lactation : official journal of International Lactation Consultant Association, 2002, Volume: 18, Issue:4

    Topics: Adult; Female; Humans; Muscle, Smooth, Vascular; Nifedipine; Nipples; Raynaud Disease; Spasm; Vascul

2002
A patient with recurrent syncope and ST-elevation on the electrocardiogram.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2004, Volume: 6, Issue:4

    Topics: Calcium Channel Blockers; Coronary Disease; Electrocardiography; Female; Humans; Middle Aged; Nifedi

2004
Nifedipine in the treatment of diffuse oesophageal spasm.
    Lancet (London, England), 1982, Dec-04, Volume: 2, Issue:8310

    Topics: Esophageal Diseases; Humans; Male; Middle Aged; Nifedipine; Pyridines; Spasm

1982
Arterial spasm during renal angioplasty.
    Radiology, 1983, Volume: 149, Issue:1

    Topics: Adolescent; Adult; Aged; Angioplasty, Balloon; Arterial Occlusive Diseases; Arteriosclerosis; Child;

1983
Successful treatment of ergotism with nifedipine.
    AJR. American journal of roentgenology, 1984, Volume: 143, Issue:2

    Topics: Angiography; Aortography; Caffeine; Drug Combinations; Ergotamine; Ergotism; Female; Humans; Ischemi

1984
[Prevention of vascular spasm during hyperselective carotid-vertebral catheterization].
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1983, Volume: 24, Issue:6

    Topics: Adult; Carotid Artery Diseases; Catheterization; Humans; Isosorbide Dinitrate; Nifedipine; Spasm; Ve

1983
Nifedipine therapy for coronary-artery spasm. Experience in 127 patients.
    The New England journal of medicine, 1980, Jun-05, Volume: 302, Issue:23

    Topics: Adult; Aged; Angina Pectoris; Angina Pectoris, Variant; Coronary Disease; Female; Humans; Male; Midd

1980
Pathophysiology and treatment of coronary arterial spasm.
    Chest, 1980, Volume: 78, Issue:1 Suppl

    Topics: Adult; Angina Pectoris; Angina Pectoris, Variant; Atropine; Calcium; Coronary Disease; Coronary Vess

1980
Nifedipine for relief of esophageal chest pain?
    The New England journal of medicine, 1982, Nov-11, Volume: 307, Issue:20

    Topics: Esophageal Diseases; Humans; Nifedipine; Pain; Pyridines; Spasm; Thorax

1982
The angiographic effect of ergonovine and nifedipine in coronary artery spasm.
    Circulation, 1980, Volume: 62, Issue:5

    Topics: Adult; Coronary Vessels; Electrocardiography; Ergonovine; Humans; Male; Nifedipine; Pyridines; Radio

1980
Relief of spasticity in SCI men and women using rectal probe electrostimulation.
    Paraplegia, 1993, Volume: 31, Issue:11

    Topics: Adult; Electric Stimulation Therapy; Equipment and Supplies; Female; Humans; Knee; Male; Motion; Nif

1993
Brief report: treatment of vasospastic amaurosis fugax with calcium-channel blockers.
    The New England journal of medicine, 1993, Aug-05, Volume: 329, Issue:6

    Topics: Adult; Aged; Blindness; Carotid Stenosis; Embolism; Female; Humans; Male; Middle Aged; Nifedipine; R

1993
Cellular localization of the inhibitory action of relaxin against uterine spasm.
    British journal of pharmacology, 1995, Volume: 116, Issue:7

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Benzopyrans; Calcium; Calcium Channel Agonists; Calciu

1995
Cerebral arterial spasm: part 9. In vitro effects of nifedipine on serotonin-, phenylephrine-, and potassium-induced contractions of canine basilar and femoral arteries.
    Neurosurgery, 1979, Volume: 4, Issue:1

    Topics: Animals; Basilar Artery; Calcium; Cerebral Arterial Diseases; Dogs; Dose-Response Relationship, Drug

1979
Cerebral arterial spasm: part 10. Reversal of acute and chronic spasm in dogs with orally administered nifedipine.
    Neurosurgery, 1979, Volume: 4, Issue:1

    Topics: Acute Disease; Administration, Oral; Animals; Cerebral Arterial Diseases; Chronic Disease; Dogs; Dru

1979
Symposium on nifedipine and calcium flux inhibition in the treatment of coronary arterial spasm and myocardial ischemia. Introduction.
    The American journal of cardiology, 1979, Oct-22, Volume: 44, Issue:5

    Topics: Adult; Angina Pectoris; Calcium; Cardiomyopathies; Coronary Disease; Electrocardiography; Humans; Ma

1979
Nifedipine therapy for refractory coronary arterial spasm.
    The American journal of cardiology, 1979, Oct-22, Volume: 44, Issue:5

    Topics: Adult; Aged; Coronary Disease; Ergonovine; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged;

1979
Nifedipine in the treatment of Prinzmetal's (variant) angina.
    The American journal of cardiology, 1979, Oct-22, Volume: 44, Issue:5

    Topics: Adult; Aged; Angina Pectoris; Angina Pectoris, Variant; Cold Temperature; Coronary Angiography; Dose

1979
Effects of nifedipine after intravenous and intracoronary administration.
    The American journal of cardiology, 1979, Oct-22, Volume: 44, Issue:5

    Topics: Aged; Angina Pectoris; Angina Pectoris, Variant; Coronary Circulation; Coronary Vessels; Dose-Respon

1979
Types of spasm and their diagnosis.
    The American journal of cardiology, 1979, Oct-22, Volume: 44, Issue:5

    Topics: Angina Pectoris, Variant; Coronary Disease; Diagnosis, Differential; Humans; Nifedipine; Spasm

1979
Nifedipine in variant angina and role of spasm in ischemic heart disease.
    The American journal of cardiology, 1979, Oct-22, Volume: 44, Issue:5

    Topics: Angina Pectoris; Angina Pectoris, Variant; Coronary Disease; Humans; Nifedipine; Pyridines; Spasm

1979
Clinical experience with nifedipine for coronary artery spasm.
    Medical times, 1979, Volume: 107, Issue:12

    Topics: Aged; Angina Pectoris, Variant; Coronary Vessels; Female; Humans; Middle Aged; Nifedipine; Pyridines

1979
[Clinical and experimental studies on the efficiency of nifedipine on smooth muscle strips of the esophagus (author's transl)].
    Zeitschrift fur Gastroenterologie, 1977, Volume: 15, Issue:11

    Topics: Adult; Animals; Dogs; Dose-Response Relationship, Drug; Esophageal Achalasia; Esophagus; Female; Hum

1977
["Dynamic" component of carotid artery stenosis in patients with cerebrovascular disorders].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1991, Volume: 91, Issue:1

    Topics: Adult; Aged; Brain; Brain Ischemia; Carotid Artery Diseases; Carotid Artery, Internal; Humans; Middl

1991
Cerebral-artery spasm in vitro.
    Lancet (London, England), 1990, Jan-13, Volume: 335, Issue:8681

    Topics: Arteriosclerosis; Cerebral Arteries; Dinoprost; Humans; In Vitro Techniques; Muscle Contraction; Nif

1990
Diffusing capacity of the lung and nifedipine in systemic sclerosis.
    Arthritis and rheumatism, 1990, Volume: 33, Issue:11

    Topics: Adult; Carbon Monoxide; Drug Administration Schedule; Female; Hemodynamics; Humans; Lung Diseases; M

1990
Do vasospasms provoke ocular diseases?
    Angiology, 1990, Volume: 41, Issue:3

    Topics: Adolescent; Adult; Aged; Blood Flow Velocity; Capillaries; Cold Temperature; Fingers; Glaucoma; Huma

1990
[Disorders of esophageal motility as a cause of retrosternal pain].
    Terapevticheskii arkhiv, 1986, Volume: 58, Issue:2

    Topics: Adult; Diagnosis, Differential; Esophageal Diseases; Esophagitis, Peptic; Female; Gastrointestinal M

1986
Nifedipine therapy for diffuse esophageal spasm.
    Southern medical journal, 1986, Volume: 79, Issue:7

    Topics: Dizziness; Drug Evaluation; Esophageal Diseases; Female; Headache; Humans; Male; Manometry; Nifedipi

1986