nifedipine has been researched along with Melanoma in 4 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| " A model system, consisting of malignant melanoma cells pretreated with the calcium sensitive fluorescent dye, Fluo-3, was used to examine the intracellular calcium dynamics in single-cell photolysis experiments." | 3.70 | Intracellular calcium dynamics during photolysis. ( Busch, NA; Reiken, SR; Toner, M; Yarmush, ML, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Honn, KV | 2 |
| Onoda, JM | 2 |
| Diglio, CA | 1 |
| Sloane, BF | 2 |
| Shih, YL | 1 |
| Lo, SJ | 1 |
| Busch, NA | 1 |
| Reiken, SR | 1 |
| Toner, M | 1 |
| Yarmush, ML | 1 |
| Jacobs, JR | 1 |
| Taylor, JD | 1 |
4 other studies available for nifedipine and Melanoma
| Article | Year |
|---|---|
Calcium channel blockers: potential antimetastatic agents.
Topics: Animals; Calcium Channel Blockers; Cell Adhesion; Cells, Cultured; Dose-Response Relationship, Drug; | 1983 |
Induction of cell expansion of goldfish melanocytoma cells (GMM-1) by epinephrine and dexamethasone requires external calcium.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Cell Line; Cell Size; Clonidine; Colforsin | 1993 |
Intracellular calcium dynamics during photolysis.
Topics: Aniline Compounds; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Humans; M | 1998 |
Cisplatin and nifedipine: synergistic cytotoxicity against murine solid tumors and their metastases.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cells, Cultured; Cisplatin; Drug Evaluation | 1986 |