nifedipine has been researched along with Magnesium Deficiency in 12 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Magnesium Deficiency: A nutritional condition produced by a deficiency of magnesium in the diet, characterized by anorexia, nausea, vomiting, lethargy, and weakness. Symptoms are paresthesias, muscle cramps, irritability, decreased attention span, and mental confusion, possibly requiring months to appear. Deficiency of body magnesium can exist even when serum values are normal. In addition, magnesium deficiency may be organ-selective, since certain tissues become deficient before others. (Harrison's Principles of Internal Medicine, 12th ed, p1936)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The mechanisms underlying the enhanced contractile response to phenylephrine (PE) and increased susceptibility to nifedipine of de-endothelialized thoracic aorta isolated from rats with dietary magnesium deficiency (Mg-deficient rats) were examined by functional and radioligand binding studies." | 7.69 | Mechanisms of the enhanced contractile response to phenylephrine in thoracic aorta isolated from rats with dietary magnesium deficiency. ( Nishio, A; Sakaguchi, H, 1994) |
| "The effects of nifedipine on the survival rate and the cardiovascular calcinosis were investigated in dietary magnesium (Mg)-deficient mice." | 7.68 | Beneficial effects of a calcium antagonist, nifedipine, on death and cardiovascular calcinosis induced by dietary magnesium deficiency in adult mice. ( Ishiguro, S; Nishio, A; Sakaguchi, H; Sakaguchi, R, 1992) |
| " Application of APV and nifedipine exacerbated low Mg(2+)-induced ILEs in the hippocampus but not the neocortex, indicating a distinct pharmacology for partial seizures of different brain regions." | 3.73 | Increased seizure susceptibility of the hippocampus compared with the neocortex of the immature mouse brain in vitro. ( Abdelmalik, PA; Burnham, WM; Carlen, PL, 2005) |
| "The mechanisms underlying the enhanced contractile response to phenylephrine (PE) and increased susceptibility to nifedipine of de-endothelialized thoracic aorta isolated from rats with dietary magnesium deficiency (Mg-deficient rats) were examined by functional and radioligand binding studies." | 3.69 | Mechanisms of the enhanced contractile response to phenylephrine in thoracic aorta isolated from rats with dietary magnesium deficiency. ( Nishio, A; Sakaguchi, H, 1994) |
| "The effects of nifedipine on the survival rate and the cardiovascular calcinosis were investigated in dietary magnesium (Mg)-deficient mice." | 3.68 | Beneficial effects of a calcium antagonist, nifedipine, on death and cardiovascular calcinosis induced by dietary magnesium deficiency in adult mice. ( Ishiguro, S; Nishio, A; Sakaguchi, H; Sakaguchi, R, 1992) |
| "Nifedipine and digoxin were selected as agents to test this hypothesis." | 1.28 | Sodium pump and calcium channel modulation of Mg-deficiency cardiomyopathy. ( Ahmad, A; Bloom, S, 1989) |
| "Nifedipine was added to the diet for 4 weeks in concentrations of 300 and 1000 ppm." | 1.27 | Influence of magnesium on blood pressure and the effect of nifedipine in rats. ( Müller, HM; Overlack, A; Ressel, C; Stumpe, KO; Zenzen, JG, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (50.00) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gorji, A | 1 |
| Moddel, G | 1 |
| Speckmann, EJ | 1 |
| Abdelmalik, PA | 1 |
| Burnham, WM | 1 |
| Carlen, PL | 1 |
| Altura, BM | 1 |
| Altura, BT | 1 |
| Moe, BH | 1 |
| Sakaguchi, H | 3 |
| Ishiguro, S | 3 |
| Miyamoto, A | 1 |
| Nishio, A | 4 |
| Sakaguchi, R | 1 |
| Rishi, M | 1 |
| Ahmad, A | 2 |
| Makheja, A | 1 |
| Karcher, D | 1 |
| Bloom, S | 2 |
| Shimonishi, I | 1 |
| Hirota, A | 1 |
| Ku, DD | 1 |
| Ann, HS | 1 |
| Overlack, A | 1 |
| Zenzen, JG | 1 |
| Ressel, C | 1 |
| Müller, HM | 1 |
| Stumpe, KO | 1 |
1 review available for nifedipine and Magnesium Deficiency
| Article | Year |
|---|---|
Microcirculatory actions and uses of naturally-occurring (magnesium) and novel synthetic calcium channel blockers.
Topics: Anesthesia; Animals; Arterioles; Blood Pressure; Calcium; Calcium Channel Blockers; Cell Membrane Pe | 1984 |
11 other studies available for nifedipine and Magnesium Deficiency
| Article | Year |
|---|---|
Background potassium concentrations and epileptiform discharges. II. Involvement of calcium channels.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Epilepsy; Extracellular Space; Female; | 2003 |
Increased seizure susceptibility of the hippocampus compared with the neocortex of the immature mouse brain in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium Channel Blockers | 2005 |
On the therapeutic mechanism of Mg2+ in digitoxic arrhythmias and the role of cardiac glycosides in Mg depletion.
Topics: Animals; Arrhythmias, Cardiac; Calcium; Cardiac Glycosides; Digitoxin; Dogs; Female; Heart; Magnesiu | 1984 |
Enhanced contractile response to phenylephrine and increased density of [3H]PN200-110 binding sites in thoracic aorta isolated from dietary magnesium-deficient rats.
Topics: Animals; Aorta, Thoracic; Calcium Channels; Diet; Endothelium, Vascular; Isradipine; Magnesium Defic | 1994 |
Mechanisms of the enhanced contractile response to phenylephrine in thoracic aorta isolated from rats with dietary magnesium deficiency.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aorta, Thoracic; Diet; In Vitro Techniques; | 1994 |
Beneficial effects of a calcium antagonist, nifedipine, on death and cardiovascular calcinosis induced by dietary magnesium deficiency in adult mice.
Topics: Animals; Aortic Diseases; Calcinosis; Calcium; Cardiomyopathies; Diet; Magnesium; Magnesium Deficien | 1992 |
Effects of reduced dietary magnesium on platelet production and function in hamsters.
Topics: Animals; Blood Platelets; Body Weight; Coronary Disease; Cricetinae; Diet; Magnesium Deficiency; Mal | 1990 |
Sodium pump and calcium channel modulation of Mg-deficiency cardiomyopathy.
Topics: Animals; Calcium; Calcium Channels; Cardiomyopathies; Cricetinae; Digoxin; Dose-Response Relationshi | 1989 |
Enhanced contractile response to noradrenaline and calcium influx in thoracic aorta isolated from dietary magnesium deficient rats.
Topics: Animals; Aorta, Thoracic; Calcium; Calcium Radioisotopes; Diet; Magnesium; Magnesium Deficiency; Mal | 1989 |
Magnesium deficiency produces endothelium-dependent vasorelaxation in canine coronary arteries.
Topics: Amiloride; Animals; Coronary Vessels; Dogs; Endothelium; Female; Magnesium Deficiency; Male; Nifedip | 1987 |
Influence of magnesium on blood pressure and the effect of nifedipine in rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Diet; Magnesium; Magnesium Deficiency; Nifedipine; | 1987 |