nifedipine has been researched along with Long QT Syndrome in 10 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 60-year-old man receiving nifedipine was admitted in a comatose condition 3 h after ingesting 5,000 mg of eperisone and 2." | 3.76 | A case of torsades de pointes induced by severe QT prolongation after an overdose of eperisone and triazolam in a patient receiving nifedipine. ( Amino, M; Inokuchi, S; Morita, S; Saito, T; Yamagiwa, T; Yamamoto, R, 2010) |
| "Ondansetron is a 5-HT3 receptor antagonist commonly prescribed to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, and surgery but may increase the risk of developing prolongation of the QT interval of the electrocardiogram, which can lead to an abnormal and potentially fatal heart rhythm and recently raised FDA concerns and warnings." | 1.38 | Nifedipine blocks ondansetron electrophysiological effects in rabbit purkinje fibers and decreases early after depolarization incidence. ( Gerard, JL; Hanouz, JL; Lemoine, S; Plaud, B; Puddu, PE; Rouet, R; Salle, L; Worou, ME, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nogawa, H | 1 |
| Muraki, Y | 1 |
| Kawai, T | 1 |
| Kuninishi, Y | 1 |
| Li, G | 1 |
| Wang, J | 1 |
| Liao, P | 1 |
| Bartels, P | 1 |
| Zhang, H | 1 |
| Yu, D | 1 |
| Liang, MC | 1 |
| Poh, KK | 1 |
| Yu, CY | 1 |
| Jiang, F | 1 |
| Yong, TF | 1 |
| Wong, YP | 1 |
| Hu, Z | 1 |
| Huang, H | 1 |
| Zhang, G | 1 |
| Galupo, MJ | 1 |
| Bian, JS | 1 |
| Ponniah, S | 1 |
| Trasti, SL | 1 |
| See, K | 1 |
| Foo, R | 1 |
| Hoppe, UC | 1 |
| Herzig, S | 1 |
| Soong, TW | 1 |
| Calorio, C | 1 |
| Gavello, D | 1 |
| Guarina, L | 1 |
| Salio, C | 1 |
| Sassoè-Pognetto, M | 1 |
| Riganti, C | 1 |
| Bianchi, FT | 1 |
| Hofer, NT | 1 |
| Tuluc, P | 1 |
| Obermair, GJ | 1 |
| Defilippi, P | 1 |
| Balzac, F | 1 |
| Turco, E | 1 |
| Bett, GC | 1 |
| Rasmusson, RL | 1 |
| Carbone, E | 1 |
| Yamagiwa, T | 1 |
| Amino, M | 1 |
| Morita, S | 1 |
| Yamamoto, R | 1 |
| Saito, T | 1 |
| Inokuchi, S | 1 |
| Rouet, R | 1 |
| Worou, ME | 1 |
| Puddu, PE | 1 |
| Lemoine, S | 1 |
| Plaud, B | 1 |
| Salle, L | 1 |
| Gerard, JL | 1 |
| Hanouz, JL | 1 |
| Sheng, X | 1 |
| Nakada, T | 1 |
| Kobayashi, M | 1 |
| Kashihara, T | 1 |
| Shibazaki, T | 1 |
| Horiuchi-Hirose, M | 1 |
| Gomi, S | 1 |
| Hirose, M | 1 |
| Aoyama, T | 1 |
| Yamada, M | 1 |
| Shiotani, M | 1 |
| Harada, T | 1 |
| Abe, J | 1 |
| Sawada, Y | 1 |
| Hashimoto, K | 1 |
| Hamada, Y | 1 |
| Horii, I | 1 |
| Thomas, G | 2 |
| Killeen, MJ | 2 |
| Gurung, IS | 2 |
| Hakim, P | 2 |
| Balasubramaniam, R | 1 |
| Goddard, CA | 2 |
| Grace, AA | 2 |
| Huang, CL | 2 |
| Mahaut-Smith, MP | 1 |
| Colledge, WH | 1 |
| Tian, XL | 1 |
| Cheng, Y | 1 |
| Zhang, T | 1 |
| Liao, ML | 1 |
| Yong, SL | 1 |
| Wang, QK | 1 |
10 other studies available for nifedipine and Long QT Syndrome
| Article | Year |
|---|---|
Pharmacological characterisation of electrocardiogram J-T
Topics: Animals; DNA-Binding Proteins; Electrocardiography; Flecainide; Guinea Pigs; Long QT Syndrome; Nifed | 2022 |
Exclusion of alternative exon 33 of Ca
Topics: Action Potentials; Alternative Splicing; Animals; Calcium Channel Blockers; Calcium Channels, L-Type | 2017 |
Impaired chromaffin cell excitability and exocytosis in autistic Timothy syndrome TS2-neo mouse rescued by L-type calcium channel blockers.
Topics: Action Potentials; Animals; Autistic Disorder; Calcium; Calcium Channel Blockers; Calcium Channels, | 2019 |
A case of torsades de pointes induced by severe QT prolongation after an overdose of eperisone and triazolam in a patient receiving nifedipine.
Topics: Anti-Anxiety Agents; Calcium Channel Blockers; Coma; Drug Interactions; Drug Overdose; Electrocardio | 2010 |
Nifedipine blocks ondansetron electrophysiological effects in rabbit purkinje fibers and decreases early after depolarization incidence.
Topics: Animals; Antiemetics; Calcium Channel Blockers; Calcium Channels, L-Type; Dose-Response Relationship | 2012 |
Two mechanistically distinct effects of dihydropyridine nifedipine on CaV1.2 L-type Ca²⁺ channels revealed by Timothy syndrome mutation.
Topics: Allosteric Regulation; Animals; Autistic Disorder; Calcium Channel Blockers; Calcium Channels, L-Typ | 2012 |
Practical application of guinea pig telemetry system for QT evaluation.
Topics: Animals; Anti-Arrhythmia Agents; Antipsychotic Agents; Bepridil; Cisapride; Disease Models, Animal; | 2005 |
Mechanisms of ventricular arrhythmogenesis in mice following targeted disruption of KCNE1 modelling long QT syndrome 5.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; | 2007 |
Effects of L-type Ca2+ channel antagonism on ventricular arrhythmogenesis in murine hearts containing a modification in the Scn5a gene modelling human long QT syndrome 3.
Topics: Action Potentials; Aniline Compounds; Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Calci | 2007 |
Optical mapping of ventricular arrhythmias in LQTS mice with SCN5A mutation N1325S.
Topics: Animals; Arrhythmias, Cardiac; Asparagine; Cardiac Complexes, Premature; Long QT Syndrome; Mexiletin | 2007 |