nifedipine has been researched along with Leukemia in 3 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ryodipine is a recently developed dihydropyridine calcium channel blocker, chemically similar to nifedipine but with some advantages: light stability, low toxicity, etc." | 5.28 | Ryodipine-induced enhancement of farmarubicin cytotoxicity against human leukemia cells in vitro. ( Ancheva, M; Mircheva, J; Staneva-Stoytcheva, D, 1990) |
| "We studied the effect of verapamil on Pgp expression (Pgp) in MDR human leukemia cell lines, K562/ADR and CEM VLB100." | 3.69 | Verapamil decreases P-glycoprotein expression in multidrug-resistant human leukemic cell lines. ( Bailly, JD; Bordier, C; Goubin, F; Jaffrézou, JP; Laredo, J; Laurent, G; Muller, C, 1994) |
| "Ryodipine is a recently developed dihydropyridine calcium channel blocker, chemically similar to nifedipine but with some advantages: light stability, low toxicity, etc." | 1.28 | Ryodipine-induced enhancement of farmarubicin cytotoxicity against human leukemia cells in vitro. ( Ancheva, M; Mircheva, J; Staneva-Stoytcheva, D, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gregorio-King, CC | 1 |
| Gough, T | 1 |
| Van Der Meer, GJ | 1 |
| Hosking, JB | 1 |
| Waugh, CM | 1 |
| McLeod, JL | 1 |
| Collier, FM | 1 |
| Kirkland, MA | 1 |
| Muller, C | 1 |
| Bailly, JD | 1 |
| Goubin, F | 1 |
| Laredo, J | 1 |
| Jaffrézou, JP | 1 |
| Bordier, C | 1 |
| Laurent, G | 1 |
| Mircheva, J | 1 |
| Staneva-Stoytcheva, D | 1 |
| Ancheva, M | 1 |
3 other studies available for nifedipine and Leukemia
| Article | Year |
|---|---|
Mechanisms of resistance to the cytotoxic effects of oxysterols in human leukemic cells.
Topics: Amino Acid Sequence; Base Sequence; DNA Primers; HL-60 Cells; Humans; Leukemia; Molecular Sequence D | 2004 |
Verapamil decreases P-glycoprotein expression in multidrug-resistant human leukemic cell lines.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Diltiazem; Drug Resistanc | 1994 |
Ryodipine-induced enhancement of farmarubicin cytotoxicity against human leukemia cells in vitro.
Topics: Calcium Channel Blockers; Cell Survival; Drug Synergism; Epirubicin; Humans; Leukemia; Nifedipine; T | 1990 |