nifedipine has been researched along with Lambert-Eaton Myasthenic Syndrome in 4 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Lambert-Eaton Myasthenic Syndrome: An autoimmune disease characterized by weakness and fatigability of proximal muscles, particularly of the pelvic girdle, lower extremities, trunk, and shoulder girdle. There is relative sparing of extraocular and bulbar muscles. CARCINOMA, SMALL CELL of the lung is a frequently associated condition, although other malignancies and autoimmune diseases may be associated. Muscular weakness results from impaired impulse transmission at the NEUROMUSCULAR JUNCTION. Presynaptic calcium channel dysfunction leads to a reduced amount of acetylcholine being released in response to stimulation of the nerve. (From Adams et al., Principles of Neurology, 6th ed, pp 1471)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grassi, C | 2 |
| Magnelli, V | 2 |
| Carabelli, V | 1 |
| Sher, E | 2 |
| Carbone, E | 2 |
| Parlatore, E | 1 |
| Xu, YF | 1 |
| Hewett, SJ | 1 |
| Atchison, WD | 1 |
| Pancrazio, JJ | 1 |
| Oie, HK | 1 |
| Kim, YI | 1 |
4 other studies available for nifedipine and Lambert-Eaton Myasthenic Syndrome
| Article | Year |
|---|---|
Inhibition of low- and high-threshold Ca2+ channels of human neuroblastoma IMR32 cells by Lambert-Eaton myasthenic syndrome (LEMS) IgGs.
Topics: Calcium Channel Blockers; Calcium Channels; Differential Threshold; Electric Conductivity; Humans; I | 1994 |
Down-regulation of non-L-, non-N-type (Q-like) Ca2+ channels by Lambert-Eaton myasthenic syndrome (LEMS) antibodies in rat insulinoma RINm5F cells.
Topics: Animals; Autoantibodies; Calcium Channel Blockers; Calcium Channels; Down-Regulation; Humans; Immuno | 1996 |
Passive transfer of Lambert-Eaton myasthenic syndrome induces dihydropyridine sensitivity of ICa in mouse motor nerve terminals.
Topics: Animals; Autoantibodies; Binding, Competitive; Calcium; Calcium Channel Blockers; Dihydropyridines; | 1998 |
Voltage-sensitive calcium channels in a human small-cell lung cancer cell line.
Topics: Calcium Channels; Carcinoma, Small Cell; Humans; Lambert-Eaton Myasthenic Syndrome; Lung Neoplasms; | 1992 |