nifedipine has been researched along with Kidney Failure, Chronic in 68 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The antihypertensive efficacy and safety of mibefradil and nifedipine SR were compared in 143 patients with chronic renal failure and mild-to-moderate hypertension in a multicenter, double-blind, randomized, parallel-design study." | 9.08 | A comparison of the safety and efficacy of mibefradil and nifedipine SR in patients with renal disease and hypertension. ( Bailey, R; Huysmans, FT; Kobrin, I; Mion Júnior, D; Robson, RA; Villa, G; Woittiez, AJ, 1998) |
| " Benidipine treatment was associated with higher cardiovascular- and cardiac event-free rates than diltiazem treatment, and higher stroke- and ESRD-free rates than nifedipine." | 7.74 | Prognostic effects of calcium channel blockers on cardiac events, stroke and end-stage renal disease in patients with angina pectoris. Retrospective comparative study of benidipine, diltiazem and nifedipine. ( Arioka, I; Dohi, S; Sakai, K, 2008) |
| "The results of a case-control study of 300 cataract patients and 609 controls indicate that long-term use of aspirin-like analgesics halves the risk of cataract." | 7.67 | Do aspirin-like analgesics protect against cataract? A case-control study. ( Harding, JJ; van Heyningen, R, 1986) |
| "In patients with chronic renal failure, decrement in BP was 25/16 mmHg (systolic and diastolic BP, respectively)." | 6.65 | [Hypotensive properties of nisoldipine. Comparative study in essential, renal and renovascular hypertension]. ( Breuer, G; Kaufmann, W; Wambach, G, 1984) |
| "26 patients with hypertension while on hemodialysis or continuous ambulatory peritoneal dialysis for end-stage renal diseases were treated first with enalapril and then changed to metoprolol." | 5.08 | A comparison of the effect of enalapril and metoprolol on renal function, potassium balance, lipid profile, cardiac function, exercise tolerance and quality of life in hypertensive dialysis patients. ( Lai, KN; Lam, WK; Li, KT; Lui, SF; Nicholls, MG; Wong, KC; Woo, KS, 1995) |
| " Angiotensin converting enzyme inhibitors (ACE-I) significantly retarded the development of end-stage renal failure compared to antihypertensives other than ACE-I (mostly nifedipine), and the effect was evident particularly in patients with proteinuria below the median (2." | 5.08 | Predictors of the progression of diabetic nephropathy and the beneficial effect of angiotensin-converting enzyme inhibitors in NIDDM patients. ( Babazono, T; Hirayama, M; Ishii, A; Omori, Y; Takahashi, C; Takeda, M; Tomonaga, O; Ujihara, U; Yokoyama, H, 1997) |
| "The antihypertensive efficacy and safety of mibefradil and nifedipine SR were compared in 143 patients with chronic renal failure and mild-to-moderate hypertension in a multicenter, double-blind, randomized, parallel-design study." | 5.08 | A comparison of the safety and efficacy of mibefradil and nifedipine SR in patients with renal disease and hypertension. ( Bailey, R; Huysmans, FT; Kobrin, I; Mion Júnior, D; Robson, RA; Villa, G; Woittiez, AJ, 1998) |
| "Mibefradil is a calcium antagonist approved for the treatment of hypertension and chronic stable angina pectoris." | 5.08 | Steady-state trough plasma mibefradil concentrations and correlation to blood pressure response in hypertensive patients with chronic renal disease. ( Pordy, R; Woittiez, A, 1998) |
| " Benidipine treatment was associated with higher cardiovascular- and cardiac event-free rates than diltiazem treatment, and higher stroke- and ESRD-free rates than nifedipine." | 3.74 | Prognostic effects of calcium channel blockers on cardiac events, stroke and end-stage renal disease in patients with angina pectoris. Retrospective comparative study of benidipine, diltiazem and nifedipine. ( Arioka, I; Dohi, S; Sakai, K, 2008) |
| "A 66-year-old hypertensive diabetic patient with latent hypoaldosteronism and mild renal failure was treated by adding enalapril, an angiotensin converting enzyme inhibitor, to the furosemide and nifedipine regimen because of an insufficient antihypertensive response for 1 month." | 3.69 | Reversible hyperkalemia during antihypertensive therapy in a hypertensive diabetic patient with latent hypoaldosteronism and mild renal failure. ( Azukizawa, S; Kaneko, M; Kigoshi, T; Matsui, A; Morimoto, S; Nakano, S; Uchida, K, 1994) |
| "Pharmacokinetics and pharmacodynamics of nifedipine were studied in 12 patients with renal failure and hypertension, after a single dose and during an 18-week treatment period." | 3.68 | Nifedipine as an antihypertensive drug in patients with renal failure--pharmacokinetics and effects. ( Anderson, P; Bondesson, U; Odar-Cederlöf, I, 1990) |
| "The results of a case-control study of 300 cataract patients and 609 controls indicate that long-term use of aspirin-like analgesics halves the risk of cataract." | 3.67 | Do aspirin-like analgesics protect against cataract? A case-control study. ( Harding, JJ; van Heyningen, R, 1986) |
| "Proteinuria is associated with adverse cardiovascular and renal outcomes that are not prevented by current treatments." | 2.76 | Selective endothelin-A receptor antagonism reduces proteinuria, blood pressure, and arterial stiffness in chronic proteinuric kidney disease. ( Dhaun, N; Goddard, J; Haughie, S; Johnston, NR; Kerr, D; MacIntyre, IM; Melville, V; Webb, DJ, 2011) |
| "Calcium channel blockers facilitate the renal excretion of sodium and this effect is maintained during chronic administration of these drugs." | 2.68 | The natriuretic effect of nifedipine gastrointestinal therapeutic system remains despite the presence of mild-to-moderate renal failure. ( Barrios, V; Campo, C; Esteban, E; Garcia-Vallejo, O; Lahera, V; Manero, M; Rodicio, JL; Ruilope, LM, 1997) |
| "In patients with chronic renal failure, decrement in BP was 25/16 mmHg (systolic and diastolic BP, respectively)." | 2.65 | [Hypotensive properties of nisoldipine. Comparative study in essential, renal and renovascular hypertension]. ( Breuer, G; Kaufmann, W; Wambach, G, 1984) |
| " Chronic administration of N(omega)-nitro-L-arginine methyl ester (L-NAME) caused systemic arterial hypertension, endothelial injury, and renal dysfunction." | 2.45 | Drug discovery for overcoming chronic kidney disease (CKD): development of drugs on endothelial cell protection for overcoming CKD. ( Fukuhara, Y; Hamano, S; Horinouchi, Y; Ishizawa, K; Tajima, S; Tamaki, T; Tomita, S; Tsuchiya, K; Yamaguchi, K, 2009) |
| " These products are well absorbed from the gastrointestinal tract but undergo variable degrees of transformation during the first passage through the liver." | 2.37 | [Clinical pharmacology of calcium inhibitors]. ( Martre, H; Singlas, E; Taburet, AM, 1985) |
| "Pregnancy in patients with chronic renal failure occurs rarely but the incidence is increasing." | 1.37 | Successful management of a high-risk pregnancy with polyhydramnios, IUGR and recurrent pregnancy loss in a chronic renal failure patient: a case report. ( Baykal, C; Kaya, S; Takal, MK; Yakupoğlu, U, 2011) |
| "Nifedipine was used for hypertension in 33% of SPK and was associated with better CV and amplitudes, particularly in the upper limbs, where there was less neuropathy." | 1.30 | Diabetic neuropathy after pancreas transplantation: determinants of recovery. ( Al-Harbi, IS; Allen, RD; Chapman, JR; Clouston, PD; Morris, JG; Nankivell, BJ; O'Connell, PJ, 1997) |
| "Treatment with nifedipine was associated with the return of [Ca2+]i toward normal values in both the nondiabetic (51 +/- 4." | 1.29 | Effect of treatment of hemodialysis patients with nifedipine on metabolism and function of polymorphonuclear leukocytes. ( Akmal, M; Alexiewicz, JM; Klin, M; Massry, SG; Smogorzewski, M, 1995) |
| " A compartment-independent pharmacokinetic analysis showed no difference in the absorption, elimination, or metabolism of nitrendipine between subjects with normal renal function and those with impaired renal function." | 1.27 | Pharmacokinetics of nitrendipine in patients with renal failure: comparison to normal subjects. ( Aronoff, GR, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (36.76) | 18.7374 |
| 1990's | 30 (44.12) | 18.2507 |
| 2000's | 7 (10.29) | 29.6817 |
| 2010's | 4 (5.88) | 24.3611 |
| 2020's | 2 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Okyere, P | 1 |
| Okyere, I | 1 |
| Essuman, G | 1 |
| Attakora, J | 1 |
| Serwaa, D | 1 |
| Donkoh, IE | 1 |
| Ephraim, RKD | 1 |
| Morimoto, K | 1 |
| Yoshida, T | 1 |
| Washida, N | 1 |
| Uchiyama, K | 1 |
| Nakayama, T | 1 |
| Itoh, H | 1 |
| Oya, M | 1 |
| Arioka, I | 1 |
| Dohi, S | 2 |
| Sakai, K | 1 |
| Ishizawa, K | 1 |
| Yamaguchi, K | 1 |
| Horinouchi, Y | 1 |
| Fukuhara, Y | 1 |
| Tajima, S | 1 |
| Hamano, S | 1 |
| Tomita, S | 1 |
| Tsuchiya, K | 1 |
| Tamaki, T | 2 |
| Dhaun, N | 2 |
| Macintyre, IM | 2 |
| Melville, V | 2 |
| Lilitkarntakul, P | 1 |
| Johnston, NR | 2 |
| Goddard, J | 2 |
| Webb, DJ | 2 |
| Kerr, D | 1 |
| Haughie, S | 1 |
| Baykal, C | 1 |
| Kaya, S | 1 |
| Takal, MK | 1 |
| Yakupoğlu, U | 1 |
| Ishimitsu, T | 1 |
| Ohno, E | 1 |
| Nakano, N | 1 |
| Furukata, S | 1 |
| Akashiba, A | 1 |
| Minami, J | 1 |
| Numabe, A | 1 |
| Matsuoka, H | 1 |
| Viñolo López, MC | 1 |
| Gutiérrez Rivas, PC | 1 |
| Liébana Cañada, A | 1 |
| Gil Cunquero, JM | 1 |
| Merino García, E | 1 |
| Maschio, G | 1 |
| Marcantoni, C | 1 |
| Bernich, P | 1 |
| Bellinghieri, G | 1 |
| Mazzaglia, G | 1 |
| Savica, V | 1 |
| Santoro, D | 1 |
| Kojima, M | 1 |
| Taniguchi, M | 1 |
| Sato, K | 1 |
| Ueda, R | 1 |
| Dohi, Y | 1 |
| Lilova, M | 1 |
| Aronoff, GR | 1 |
| Kusano, E | 2 |
| Asano, Y | 2 |
| Takeda, K | 2 |
| Terao, N | 1 |
| Hosoda, S | 2 |
| Ambroso, GC | 2 |
| Como, G | 2 |
| Scalamogna, A | 2 |
| Citterio, A | 2 |
| Casati, S | 2 |
| Cantaluppi, A | 1 |
| Ponticelli, C | 2 |
| Schiffl, H | 1 |
| Ziupa, J | 1 |
| Schollmeyer, P | 1 |
| Bogaert, MG | 1 |
| Rosseel, MT | 1 |
| Joos, R | 1 |
| Boelaert, J | 1 |
| Wambach, G | 1 |
| Breuer, G | 1 |
| Kaufmann, W | 1 |
| Dilmen, U | 1 |
| Cağlar, MK | 1 |
| Senses, DA | 1 |
| Kinik, E | 1 |
| Matsumoto, Y | 1 |
| Ebihara, A | 1 |
| Eliahou, HE | 3 |
| Iaina, A | 1 |
| Schneider, R | 1 |
| Cohen, D | 3 |
| Goldfarb, D | 1 |
| Gross, M | 1 |
| Alexiewicz, JM | 3 |
| Smogorzewski, M | 3 |
| Klin, M | 1 |
| Akmal, M | 3 |
| Massry, SG | 3 |
| Uchida, K | 1 |
| Azukizawa, S | 1 |
| Nakano, S | 1 |
| Kaneko, M | 1 |
| Kigoshi, T | 1 |
| Morimoto, S | 1 |
| Matsui, A | 1 |
| Sacchetti, A | 1 |
| McCabe, J | 1 |
| Torres, M | 1 |
| Harris, RL | 1 |
| Wight, JP | 3 |
| Brown, CB | 2 |
| el Nahas, AM | 3 |
| Dworkin, LD | 1 |
| Benstein, JA | 1 |
| Parker, M | 1 |
| Tolbert, E | 1 |
| Feiner, HD | 1 |
| Zucchelli, P | 2 |
| Zuccalà, A | 2 |
| Amann, K | 2 |
| Nichols, C | 2 |
| Tornig, J | 2 |
| Schwarz, U | 1 |
| Zeier, M | 2 |
| Mall, G | 2 |
| Ritz, E | 3 |
| Taylor, JE | 1 |
| Belch, JJ | 1 |
| Henderson, IS | 1 |
| Stewart, WK | 1 |
| Lanchote, VL | 1 |
| Ping, WC | 1 |
| Santos, SR | 1 |
| Acone, D | 1 |
| Cante, D | 1 |
| Cillo, F | 1 |
| Giordano, G | 1 |
| Giordano, C | 1 |
| Wong, KC | 1 |
| Woo, KS | 1 |
| Lam, WK | 1 |
| Li, KT | 1 |
| Lai, KN | 1 |
| Nicholls, MG | 1 |
| Lui, SF | 1 |
| Gill, SK | 1 |
| Allen, RD | 1 |
| Al-Harbi, IS | 1 |
| Morris, JG | 1 |
| Clouston, PD | 1 |
| O'Connell, PJ | 1 |
| Chapman, JR | 1 |
| Nankivell, BJ | 1 |
| Yokoyama, H | 1 |
| Tomonaga, O | 1 |
| Hirayama, M | 1 |
| Ishii, A | 1 |
| Takeda, M | 1 |
| Babazono, T | 1 |
| Ujihara, U | 1 |
| Takahashi, C | 1 |
| Omori, Y | 1 |
| Pitt, B | 1 |
| Campo, C | 1 |
| Garcia-Vallejo, O | 1 |
| Barrios, V | 1 |
| Lahera, V | 1 |
| Manero, M | 1 |
| Esteban, E | 1 |
| Rodicio, JL | 1 |
| Ruilope, LM | 1 |
| Woittiez, AJ | 1 |
| Huysmans, FT | 1 |
| Bailey, R | 1 |
| Robson, RA | 2 |
| Mion Júnior, D | 1 |
| Villa, G | 1 |
| Kobrin, I | 1 |
| Varga, E | 1 |
| Mair, LH | 1 |
| Pordy, R | 1 |
| Woittiez, A | 1 |
| Borghi, M | 1 |
| Fusaroli, M | 1 |
| Sasdelli, M | 1 |
| Stallone, C | 1 |
| Sanna, G | 1 |
| Gaggi, R | 1 |
| Favazza, A | 1 |
| Motanaro, D | 1 |
| Messa, P | 1 |
| Antonucci, F | 1 |
| Gropuzzo, M | 1 |
| Mioni, G | 1 |
| Hirano, T | 1 |
| Toyoshima, Y | 1 |
| Oka, K | 1 |
| Kozaki, M | 1 |
| Bassett, AH | 1 |
| Hutchesson, A | 1 |
| Thurrell, W | 1 |
| Burmak, IuG | 1 |
| Reams, G | 1 |
| Lau, A | 1 |
| Knaus, V | 1 |
| Bauer, JH | 1 |
| Natov, S | 1 |
| Pavlova, M | 1 |
| Dimitrakov, D | 1 |
| Velichkov, I | 1 |
| Bakalov, V | 1 |
| Odar-Cederlöf, I | 1 |
| Anderson, P | 1 |
| Bondesson, U | 1 |
| Salvetti, A | 1 |
| Bozzo, MV | 1 |
| Graziola, M | 1 |
| Abdel-Haq, B | 1 |
| van Harten, J | 1 |
| Burggraaf, J | 1 |
| van Brummelen, P | 1 |
| Breimer, DD | 1 |
| van Bortel, L | 1 |
| Böhm, R | 1 |
| Mooij, J | 1 |
| Schiffers, P | 1 |
| Rahn, KH | 2 |
| Mickisch, O | 1 |
| Schmid, M | 1 |
| Mann, JF | 1 |
| Helder, T | 1 |
| Bergen, F | 1 |
| Rauterberg, EW | 1 |
| van Heyningen, R | 1 |
| Harding, JJ | 1 |
| Herzog, D | 2 |
| Shechter, P | 2 |
| Serban, I | 1 |
| Kapuler, S | 2 |
| Schiby, G | 1 |
| Gavendo, S | 1 |
| Hellberg, B | 1 |
| Ben-David, A | 1 |
| Kogan, N | 1 |
| Fraenkel, M | 1 |
| Barratt, LJ | 1 |
| Birkett, DJ | 1 |
| Cacoub, P | 2 |
| Deray, G | 2 |
| Baumelou, A | 1 |
| Jacobs, C | 2 |
| Deray, JY | 1 |
| Grosgogeat, Y | 1 |
| Azar, R | 1 |
| van Bortel, LM | 1 |
| Mooy, JM | 1 |
| Mohanan, PP | 1 |
| Visweswaran, RK | 1 |
| Heidland, A | 1 |
| Riegel, W | 1 |
| Hörl, W | 1 |
| Weipert, J | 1 |
| Geiger, H | 1 |
| Heidbreder, E | 1 |
| Singlas, E | 1 |
| Martre, H | 1 |
| Taburet, AM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| THE EFFECTS OF SITAXSENTAN ONCE DAILY DOSING ON PROTEINURIA, 24-HOUR BLOOD PRESSURE, AND ARTERIAL STIFFNESS IN SUBJECTS WITH CHRONIC KIDNEY DISEASE[NCT00810732] | Phase 2 | 27 participants (Actual) | Interventional | 2007-05-09 | Completed | ||
| the Effect of Nifedipine Controlled Release Tablets in Hypertensive Patients on Chronic Maintenance Hemodialysis and the Influence of Hemodialysis on the Plasma Concentration of Nifedipine[NCT01021501] | Phase 4 | 20 participants (Anticipated) | Interventional | 2009-12-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Carotid-femoral pulse wave velocity (PWV), a measure of arterial stiffness, is determined from the time taken for the arterial pulse to propagate from the carotid to the femoral artery. Baseline was defined as the pre-dose measurement for the measure collected at Week 0 of each treatment period. Week 3 and Week 6 was an average of measurement for the measure collected at Week 3 and 6 of each treatment period. (NCT00810732)
Timeframe: Baseline, Week 3 and 6
| Intervention | Meter per second (Mean) | ||
|---|---|---|---|
| Baseline | Change at Week 3 | Change at Week 6 | |
| Nifedipine | 7.94 | -0.21 | -0.38 |
| Placebo | 7.74 | -0.21 | 0.29 |
| Sitaxsentan | 7.97 | -0.19 | -0.41 |
Mean urine total protein assessment included 24-hour urine collections to assess total protein excretion per 24 hours. Baseline was derived from an average of Week 0 (pre-dose) 24-hour urine collections prior to each treatment period. Week 6 was derived from an average of Week 6 24-hour urine collections for each treatment period. (NCT00810732)
Timeframe: Baseline, Week 6
| Intervention | Grams per 24 hours (Mean) | |
|---|---|---|
| Baseline | Change at week 6 | |
| Nifedipine | 1.95 | 0.01 |
| Placebo | 2.07 | -0.06 |
| Sitaxsentan | 2.07 | -0.62 |
The 24-hour ambulatory BP monitoring was performed by using a BP cuff which was attached to the participant's arm, using the same arm throughout the study, with a small monitor that comfortably sits in the pocket of participant. Mean values over 24-hour measurements at each measurement period were calculated. The change in total 24-hour ambulatory monitoring of systemic arterial BP, SBP and DBP at Week 3 and 6 relative to baseline were reported. Baseline was as an average of the pre-dose measurement for the measure collected at Week 0 of each treatment period. Week 3 and Week 6 was an average of measurement for the measure collected at Week 3 and 6 of each treatment period. (NCT00810732)
Timeframe: Baseline, Week 3 and 6
| Intervention | Millimeter of Mercury (mmHg) (Mean) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Mean Systemic Arterial BP: Baseline | Mean Systemic Arterial BP: Change at Week 3 | Mean Systemic Arterial BP: Change at Week 6 | Mean Systemic Arterial SBP :Baseline | Mean Systemic Arterial SBP: Change at Week 3 | Mean Systemic Arterial SBP: Change at Week 6 | Mean Systemic Arterial DBP: Baseline | Mean Systemic Arterial DBP: Change at Week 3 | Mean Systemic Arterial DBP: Change at Week 6 | |
| Nifedipine | 93.78 | -2.95 | -3.54 | 125.12 | -4.20 | -4.47 | 78.27 | -2.09 | -2.86 |
| Placebo | 92.98 | -1.20 | -0.35 | 125.17 | -2.81 | -1.57 | 77.58 | -0.86 | -0.41 |
| Sitaxsentan | 92.94 | -4.59 | -3.74 | 124.03 | -4.88 | -3.99 | 77.56 | -4.85 | -3.60 |
5 reviews available for nifedipine and Kidney Failure, Chronic
| Article | Year |
|---|---|
Bullous pemphigoid in patients receiving peritoneal dialysis: a case series and a literature survey.
Topics: Aged; Autoantibodies; Female; Humans; Icodextrin; Kidney Failure, Chronic; Male; Middle Aged; Nifedi | 2021 |
Drug discovery for overcoming chronic kidney disease (CKD): development of drugs on endothelial cell protection for overcoming CKD.
Topics: Animals; Cells, Cultured; Drug Discovery; Endothelial Cells; Humans; Kidney Failure, Chronic; Molecu | 2009 |
Lessons from large interventional trials on antihypertensive therapy in chronic renal disease.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Chronic Disease; Clini | 2002 |
Diversity of calcium antagonists.
Topics: Angina Pectoris; Arteriosclerosis; Benzimidazoles; Calcium Channel Blockers; Diltiazem; Humans; Hype | 1997 |
[Clinical pharmacology of calcium inhibitors].
Topics: Age Factors; Animals; Bepridil; Biological Availability; Biotransformation; Calcium Channel Blockers | 1985 |
20 trials available for nifedipine and Kidney Failure, Chronic
| Article | Year |
|---|---|
Blood pressure-independent reduction in proteinuria and arterial stiffness after acute endothelin-a receptor antagonism in chronic kidney disease.
Topics: Adult; Aged; Antihypertensive Agents; Arteries; Blood Pressure; Calcium Channel Blockers; Cross-Over | 2009 |
Selective endothelin-A receptor antagonism reduces proteinuria, blood pressure, and arterial stiffness in chronic proteinuric kidney disease.
Topics: Adult; Antihypertensive Agents; Arteries; Blood Pressure; Cross-Over Studies; Double-Blind Method; D | 2011 |
Combination of angiotensin II receptor antagonist with calcium channel blocker or diuretic as antihypertensive therapy for patients with chronic kidney disease.
Topics: Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2011 |
Effects of manidipine and nifedipine on blood pressure and renal function in patients with chronic renal failure: a multicenter randomized controlled trial.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Female; Humans; Hypertension; Kid | 2003 |
Antihypertensive effects of long-acting calcium channel blockers on hemodialysis days--a randomized crossover trial between benidipine and nifedipine CR.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channe | 2004 |
Acute and chronic hypotensive effects of nifedipine and niludipine in hypertensive patients with chronic renal failure.
Topics: Adolescent; Adult; Blood Pressure; Calcium Channel Blockers; Circadian Rhythm; Female; Humans; Hyper | 1984 |
[Hypotensive properties of nisoldipine. Comparative study in essential, renal and renovascular hypertension].
Topics: Adult; Aged; Aldosterone; Calcium Channel Blockers; Electrolytes; Female; Heart Rate; Humans; Hydroc | 1984 |
Blood pressure control effects on the progression of chronic renal failure.
Topics: Captopril; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Nifedipine; Pro | 1993 |
Influence of renal failure on cytochrome P450 activity in hypertensive patients using a "cocktail" of antipyrine and nifedipine.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Antipyrine; Biotransformati | 1996 |
Blood pressure and progression of renal failure in the elderly.
Topics: Aged; Aged, 80 and over; Aging; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; B | 1996 |
A comparison of the effect of enalapril and metoprolol on renal function, potassium balance, lipid profile, cardiac function, exercise tolerance and quality of life in hypertensive dialysis patients.
Topics: Adult; Anemia; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Cell Count; | 1995 |
Predictors of the progression of diabetic nephropathy and the beneficial effect of angiotensin-converting enzyme inhibitors in NIDDM patients.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel B | 1997 |
The natriuretic effect of nifedipine gastrointestinal therapeutic system remains despite the presence of mild-to-moderate renal failure.
Topics: Administration, Oral; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium | 1997 |
A comparison of the safety and efficacy of mibefradil and nifedipine SR in patients with renal disease and hypertension.
Topics: Adult; Aged; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Female; | 1998 |
Steady-state trough plasma mibefradil concentrations and correlation to blood pressure response in hypertensive patients with chronic renal disease.
Topics: Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Dose | 1998 |
Long-term comparison between captopril and nifedipine in the progression of renal insufficiency.
Topics: Adolescent; Adult; Aged; Blood Pressure; Captopril; Creatinine; Female; Humans; Hypertension, Renal; | 1992 |
Peritoneal clearances in hypertensive CAPD patients after oral administration of clonidine, enalapril, and nifedipine.
Topics: Biological Transport; Clonidine; Enalapril; Female; Humans; Hypertension; Kidney Failure, Chronic; M | 1992 |
Acute hemodynamic effect of nifedipine in hypertensives with chronic renal failure: the influence of volume status.
Topics: Adult; Blood Pressure; Glomerulonephritis; Heart Rate; Hematocrit; Hemodynamics; Humans; Hypertensio | 1987 |
[Calcium antagonists in chronic renal failure. Undesirable effects on glomerular hemodynamics?].
Topics: Adult; Albuminuria; Calcium Channel Blockers; Enalapril; Hemodynamics; Humans; Hypertension, Renal; | 1988 |
Effect of the calcium channel blocker nisoldipine on the progression of chronic renal failure in man.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Dietary Proteins; Energy Intake; Female; Huma | 1988 |
43 other studies available for nifedipine and Kidney Failure, Chronic
| Article | Year |
|---|---|
Conservative therapy is associated with worse clinical features and biochemical derangements than renal replacement therapy: a retrospective study in Kumasi, Ghana.
Topics: Adult; Aspirin; Bisoprolol; Conservative Treatment; Furosemide; Ghana; Humans; Irbesartan; Kidney Fa | 2022 |
Prognostic effects of calcium channel blockers on cardiac events, stroke and end-stage renal disease in patients with angina pectoris. Retrospective comparative study of benidipine, diltiazem and nifedipine.
Topics: Aged; Angina Pectoris; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Female; Heart Diseases | 2008 |
Successful management of a high-risk pregnancy with polyhydramnios, IUGR and recurrent pregnancy loss in a chronic renal failure patient: a case report.
Topics: Abortion, Habitual; Adult; Amniotic Fluid; Betamethasone; Birth Weight; Female; Fetal Growth Retarda | 2011 |
Clinical case: Peritoneal dialysis patient with cloudy peritoneal fluid following administration of calcium antagonists.
Topics: Adult; Antihypertensive Agents; Ascitic Fluid; Calcium Channel Blockers; Cardiovascular Agents; Chyl | 2011 |
Hypertension in children with chronic renal failure.
Topics: Antihypertensive Agents; Blood Pressure; Child; Dihydralazine; Glomerular Filtration Rate; Humans; H | 2005 |
Pharmacokinetics of nitrendipine in patients with renal failure: comparison to normal subjects.
Topics: Adult; Aged; Biotransformation; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Crea | 1984 |
Slow-release nifedipine for treatment of arterial hypertension in patients with chronic renal failure.
Topics: Adult; Aged; Delayed-Action Preparations; Female; Humans; Hypertension, Renal; Kidney Failure, Chron | 1984 |
Clinical features and management of nifedipine overdosage in a patient with renal insufficiency.
Topics: Adult; Calcium Gluconate; Female; Hemodynamics; Humans; Kidney Failure, Chronic; Nifedipine | 1984 |
Plasma concentrations of nifedipine in patients with renal failure.
Topics: Administration, Oral; Humans; Kidney Failure, Chronic; Kinetics; Nifedipine; Renal Dialysis | 1984 |
Nifedipine in hypertensive emergencies of children.
Topics: Adolescent; Blood Pressure; Child; Combined Modality Therapy; Drug Evaluation; Emergencies; Female; | 1983 |
Hypotensive effect of nifedipine in hypertensive patients with chronic renal failure.
Topics: Adolescent; Adult; Calcium; Cardiac Output; Epinephrine; Female; Hemodynamics; Humans; Hypertension, | 1982 |
Treatment of hypertension in dialysis and essential hypertension patients with nifedipine.
Topics: Humans; Hypertension, Renal; Kidney Failure, Chronic; Nifedipine; Pyridines; Renal Dialysis; Time Fa | 1982 |
Effect of treatment of hemodialysis patients with nifedipine on metabolism and function of polymorphonuclear leukocytes.
Topics: Adenosine Triphosphate; Adult; Animals; Calcium; Diabetic Nephropathies; Female; Humans; Kidney Fail | 1995 |
Reversible hyperkalemia during antihypertensive therapy in a hypertensive diabetic patient with latent hypoaldosteronism and mild renal failure.
Topics: Aged; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Therapy, Combination; Enalapril; Furos | 1994 |
ED management of acute congestive heart failure in renal dialysis patients.
Topics: Acute Disease; Administration, Cutaneous; Administration, Oral; Administration, Sublingual; Captopri | 1993 |
Effect of control of hypertension on progressive renal failure.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Female; Follow-Up Studies; Humans; Hypertension, Ren | 1993 |
Calcium antagonists and converting enzyme inhibitors reduce renal injury by different mechanisms.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Enalapril; Glomeruloscl | 1993 |
Effect of ramipril, nifedipine, and moxonidine on glomerular morphology and podocyte structure in experimental renal failure.
Topics: Animals; Antihypertensive Agents; Capillaries; Imidazoles; Kidney Failure, Chronic; Kidney Glomerulu | 1996 |
Arteriolar wall thickening, capillary rarefaction and interstitial fibrosis in the heart of rats with renal failure:the effects of ramipril, nifedipine and moxonidine.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Thoracic; Arterio | 1996 |
Peripheral microcirculatory blood flow in haemodialysis patients treated with erythropoietin.
Topics: Anemia; Antihypertensive Agents; Blood Flow Velocity; Calcium Channel Blockers; Case-Control Studies | 1996 |
A longitudinal study on the effect of nifedipine therapy and its discontinuation on [Ca2+]i and proliferation of B lymphocytes of dialysis patients.
Topics: Adult; B-Lymphocytes; Calcium; Calcium Channel Blockers; Cytosol; Female; Humans; Kidney Failure, Ch | 1997 |
Time course of the effect of nifedipine therapy and its discontinuation on [Ca2+]i and phagocytosis of polymorphonuclear leukocytes from hemodialysis patients.
Topics: Adult; Calcium; Calcium Channel Blockers; Female; Humans; Kidney Failure, Chronic; Male; Neutrophils | 1997 |
Diabetic neuropathy after pancreas transplantation: determinants of recovery.
Topics: Adult; Body Weight; Calcium Channel Blockers; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Dia | 1997 |
Medication influencing the development of gingival overgrowth in renal transplant patients.
Topics: Cyclosporine; Gingiva; Gingival Hyperplasia; Gingivitis; Humans; Immunosuppressive Agents; Kidney Fa | 1998 |
Promotion of lymphocyte blastogenesis by hemodialysate of chronic renal failure.
Topics: Allopurinol; Anabolic Agents; Androstanols; Calcitriol; Cells, Cultured; Concanavalin A; Creatinine; | 1992 |
Effect of antihypertensive therapy in experimental chronic renal failure.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Dietary Proteins; Heart; Hydralazine; Kidney Failu | 1991 |
Short-term effects of calcium antagonists on renal haemodynamics in patients with chronic renal failure.
Topics: Adolescent; Adult; Female; Hemodynamics; Humans; Kidney Failure, Chronic; Male; Middle Aged; Nifedip | 1991 |
[The use of korinfar in a disorder of the patency of the bronchi and their elevated reactivity in patients with chronic kidney failure].
Topics: Adult; Bronchi; Bronchitis; Drug Evaluation; Female; Humans; Kidney Failure, Chronic; Male; Middle A | 1991 |
The effect of nifedipine GITS on renal function in hypertensive patients with renal insufficiency.
Topics: Blood Pressure; Delayed-Action Preparations; Female; Glomerular Filtration Rate; Humans; Hypertensio | 1991 |
[The effect of nifedipine at the initial stage of its use on kidney function in patients with chronic kidney failure].
Topics: Creatinine; Drug Evaluation; Female; Humans; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Nif | 1990 |
Nifedipine as an antihypertensive drug in patients with renal failure--pharmacokinetics and effects.
Topics: Adult; Aged; Blood Pressure; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Age | 1990 |
Influence of renal function on the pharmacokinetics and cardiovascular effects of nisoldipine after single and multiple dosing.
Topics: Administration, Oral; Adult; Blood Pressure; Calcium Channel Blockers; Drug Administration Schedule; | 1989 |
Total and free steady-state plasma levels and pharmacokinetics of nifedipine in patients with terminal renal failure.
Topics: Administration, Oral; Adult; Aged; Biological Availability; Blood Proteins; Female; Humans; Infusion | 1989 |
Do aspirin-like analgesics protect against cataract? A case-control study.
Topics: Acetaminophen; Aged; Analgesics; Aspirin; Cataract; Diabetes Complications; Epidemiologic Methods; F | 1986 |
The control of hypertension and its effect on renal function in rat remnant kidney.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Creatinine; Dietary Proteins; Dihydralazine; Fema | 1988 |
Cyclosporin-verapamil interaction.
Topics: Adult; Creatinine; Cyclosporins; Drug Interactions; Humans; Kidney Failure, Chronic; Kidney Transpla | 1988 |
No evidence for protective effects of nifedipine against radiocontrast-induced acute renal failure.
Topics: Acute Kidney Injury; Contrast Media; Humans; Kidney Failure, Chronic; Nifedipine; Retrospective Stud | 1988 |
Nifedipine-induced acute renal failure.
Topics: Acute Kidney Injury; Aged; Blood Pressure; Humans; Kidney Failure, Chronic; Male; Nifedipine | 1988 |
[Aggravation of chronic renal insufficiency by nifedipine].
Topics: Creatinine; Female; Humans; Hypertension; Kidney Failure, Chronic; Middle Aged; Nifedipine | 1987 |
The use of calcium antagonists in patients with renal failure.
Topics: Calcium Channel Blockers; Diltiazem; Humans; Kidney Failure, Chronic; Nifedipine; Nitrendipine; Vera | 1987 |
Sublingual nifedipine in severe hypertension with advanced renal failure.
Topics: Administration, Oral; Adult; Aged; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Midd | 1987 |
Calcium antagonists: hypotensive and humoral actions in different forms of hypertension.
Topics: Calcium; Calcium Channel Blockers; Emergencies; Heart Rate; Homeostasis; Hormones; Humans; Hypertens | 1985 |
Treatment of arterial hypertension with nifedipine in patients with chronic renal insufficiency.
Topics: Blood Pressure; Delayed-Action Preparations; Dosage Forms; Humans; Hypertension; Kidney Failure, Chr | 1985 |