Page last updated: 2024-11-01

nifedipine and Kidney Diseases

nifedipine has been researched along with Kidney Diseases in 60 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.

Research Excerpts

ExcerptRelevanceReference
"Nilvadipine appears to be an effective hypotensive agent at single daily doses of 8 mg."5.28Nilvadipine in hypertension with renal dysfunction. ( Albert, FW; Berger, HH, 1992)
"In patients with chronic renal failure and hypertension due to primary renal disease, fosinopril significantly differed from nifedipine GITS by its capacity to slow the progressive decay in renal function."5.09A random comparison of fosinopril and nifedipine GITS in patients with primary renal disease. ( Aljama, P; Aranda, P; Diez, J; Marin, R; Ruilope, LM; Segura, J, 2001)
"A double-blind randomized, clinical trial was conducted in 43 patients to evaluate the efficacy of sublingual nifedipine in the treatment of pain in renal colic."5.06Nifedipine in the treatment of renal colic. ( Lloret, J; Monmany, J; More, J; Muñoz, J; Puig, X; Vila, A, 1986)
"Two hundred eighty-six outpatients prescribed three different CCBs (benidipine [CAS 91599-74-5], amlodipine [CAS 111470-99-6] and controlled release nifedipine (nifedipine CR) [CAS 21829-25-4]) for hypertension in combination with ARBs during a 4-year period were registered in a retrospective comparative study."3.76Effects of combination therapy with angiotensin II type I receptor blockers and calcium channel blockers on renal function in hypertensive patients/a retrospective, "real-world" comparative study. ( Futenma, A; Imai, H; Kimura, Y; Maeda, K; Miura, N; Suga, N; Yamada, H, 2010)
"Long-acting nifedipine tablets were given to 47 severely and moderately hypertensive patients with renal insufficiency, cardiovascular, cerebrovascular, and peripheral vascular disease, diabetes mellitus, asthma, and systemic lupus erythematosus."3.67Long-acting nifedipine in moderate and severe hypertensive patients with serious concomitant diseases. ( Bursztyn, M; Grossman, E; Rosenthal, T, 1985)
"25 hypertensive patients with normal or impaired renal function underwent pharmacokinetic and safety studies after single and multiple dose administration of nifedipine GITS (Gastro-Intestinal Therapeutic System) 60mg tablets."2.67Pharmacokinetic profile of nifedipine GITS in hypertensive patients with chronic renal impairment. ( Brendel, E; Griffel, L; Iaina, A; Kobelt, R; Schneider, R; Stolero, D, 1994)
"To determine whether verapamil, diltiazem, or nifedipine affect digitoxin kinetics, glycoside plasma concentrations and renal excretion were measured before and during steady-state dosing in 30 patients with cardiac insufficiency."2.66Effects of verapamil, diltiazem, and nifedipine on plasma levels and renal excretion of digitoxin. ( Kuhlmann, J, 1985)
" It compared the antihypertensive effect between increasing ARB dosage and the addition of controlled-release nifedipine."2.43[NICE-Combi study: effect of nifedipine in combination with an angiotensin II receptor blocker on BP control and renal protection]. ( Hasebe, N, 2006)
" The reported adverse effect profile for each of these drugs varies, but tends to hold true to drug class and are typified by the adverse reactions reported for nifedipine and amlodipine (dihydropyridines), diltiazem (benzothiazepines) and verapamil (phenylalkylamines)."2.39A comparative review of the adverse effects of calcium antagonists. ( Dougall, HT; McLay, J, 1996)
"Amlodipine, a dihydropyridine calcium antagonist, was synthesized in an attempt to develop a compound with a pharmacokinetic profile characteristic of this class, which would also have an increased oral bioavailability and extended clearance time."2.38The pharmacokinetic profile of amlodipine. ( Abernethy, DR, 1989)
" Nifedipine and irbesartan were taken after discharge, and the dosage was reduced gradually under supervision."1.48Hypertensive crisis with 2 target organ impairment induced by glycyrrhizin: A case report. ( Fan, X; Li, J; Wang, Q, 2018)
"Treatment with nifedipine (10, 20 mg/kg) significantly improved the renal dysfunction, tissue and urine total nitric oxide levels, and renal oxidative stress and prevented the alterations in renal morphology."1.33Nifedipine attenuates changes in nitric oxide levels, renal oxidative stress, and nephrotoxicity induced by cyclosporine. ( Chander, V; Chopra, K, 2005)
"Nifedipine and verapamil have been shown previously to protect against renal function alterations induced by shock wave lithotripsy (SWL) in humans and rats; however, the mechanism is unclear."1.30Nifedipine, verapamil and diltiazem block shock-wave-induced rises in cytosolic calcium in MDCK cells. ( Chen, WC; Jan, CR; Tseng, CJ; Wu, SN, 1998)
" For acute control of blood pressure sublingual nifedipine was used in dosage of 0."1.29Malignant hypertension in children in India. ( Arora, P; Baijal, SS; Gulati, S; Kher, V; Kumar, P; Kumar, S; Rai, PK, 1996)
"Nilvadipine appears to be an effective hypotensive agent at single daily doses of 8 mg."1.28Nilvadipine in hypertension with renal dysfunction. ( Albert, FW; Berger, HH, 1992)
" If such an effect occurs in vivo, the ATP deficit will affect calcium extrusion pumps, so triggering vasoconstriction which is the major side effect of Cyclosporine A."1.28The restoration of ATP synthesis may explain the protective effect of calcium antagonists against cyclosporine A nephrotoxicity. ( Berland, Y; Chauvet-Monges, AM; Crevat, A; Dussol, B; Elsen, R; Salducci, MD, 1992)
"Treatment with nifedipine attenuated cyclosporine A-induced renal dysfunction and reduced urinary endothelin excretion."1.28Effect of nifedipine on cyclosporine A-induced nephrotoxicity, urinary endothelin excretion and renal endothelin receptor number. ( Brooks, DP; Caltabiano, M; Contino, LC; Nambi, P; Ohlstein, EH; Pullen, M; Storer, B, 1991)
" A direct toxic effect of CsA on renal tubule epithelia was demonstrated using nigrosine uptake and LDH release as indicators of cell death."1.28Mechanisms of cyclosporine A toxicity in defined cultures of renal tubule epithelia: a role for cysteine proteases. ( Hartz, PA; Wilson, PD, 1991)
"Amlodipine was administered as 14 single 5-mg oral daily doses to 27 male subjects with renal function ranging from normal to haemodialysis-dependent."1.28Pharmacokinetics of amlodipine in renal impairment. ( Carmody, M; Donohue, J; Doyle, GD; Greb, H; Laher, M; Volz, M, 1989)
" Also on long-term administration of NIF in hypertensive patients, renal function improved."1.28[The effects of nifedipine on blood pressure and renal function]. ( Igarashi, N, 1989)
" The elimination half-life was of the order of 50 h, similar to previously observed values, and did not vary with differences in renal function."1.27Pharmacokinetics of amlodipine in renal impairment. ( Carmody, M; Donohoe, JF; Doyle, GD; Greb, H; Kelly, JG; Laher, MS; Volz, M, 1988)
" No significant differences were observed between Groups A, B and C (on an interdialysis day) in AUC (0-7h), tmax, Cmax and plasma protein binding."1.27Pharmacokinetics of nisoldipine in renal dysfunction. ( Ahr, G; Boelaert, J; Bogaert, MG; Dammekens, H; Daneels, R; De Vriese, G; Schurgers, M; Valcke, Y, 1988)

Research

Studies (60)

TimeframeStudies, this research(%)All Research%
pre-199022 (36.67)18.7374
1990's18 (30.00)18.2507
2000's11 (18.33)29.6817
2010's9 (15.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, J2
Fan, X1
Wang, Q1
Hammoud, SH1
Alkhansa, S1
Mahjoub, N1
Omar, AG1
El-Mas, MM1
Eid, AA1
Eraslan, E1
Tanyeli, A1
Polat, E2
Akindele, AJ1
Adeneye, AA1
Olatoye, F1
Benebo, AS1
Alp Yildirim, FI1
Eker Kizilay, D1
Ergin, B1
Balci Ekmekçi, Ö1
Topal, G1
Kucur, M1
Demirci Tansel, C1
Uydeş Doğan, BS1
Liu, XD1
Fu, J1
Feng, MZ1
Zhang, ZH1
Dewan, P1
Agarwal, N1
Yamada, H1
Suga, N1
Maeda, K1
Kimura, Y1
Miura, N1
Futenma, A1
Imai, H1
Veeramani, C1
Aristatle, B1
Pushpavalli, G1
Pugalendi, KV1
Ishii, T1
Kawamura, T1
Tsuboi, N1
Hosoya, T1
Maschio, G1
Marcantoni, C1
Bernich, P1
de Araujo, M1
Seguro, AC1
Miller, DC1
Wolf, JS1
Chander, V1
Chopra, K1
Xie, HH1
Shen, FM1
Zhang, XF1
Jiang, YY1
Su, DF1
Fomin, VV1
Safonov, VV1
Kozlovskaia, NL1
Moiseev, SV1
Osipenko, VI1
Tironishvili, OI1
Liu, LL1
Li, QX1
Xia, L1
Shao, L1
Hasebe, N1
Diamond, JR1
Cheung, JY1
Fang, LS1
Schneider, R1
Stolero, D1
Griffel, L1
Kobelt, R1
Brendel, E1
Iaina, A1
Mitamura, T1
Yamada, A1
Ishida, H1
Fujihira, S1
Ohara, K1
Noguchi, H1
Mine, Y1
Zawadzki, J1
Grenda, R1
Januszewicz, P1
Li, B1
Zhou, W1
Li, P1
Zucchelli, P1
Zuccalà, A1
Ghoniem, GM1
Dilworth, JP1
Roberts, JA1
Kumar, P1
Arora, P1
Kher, V1
Rai, PK1
Gulati, S1
Baijal, SS1
Kumar, S1
Balakrishnan, VS1
von Ruhland, CJ1
Griffiths, DF1
Coles, GA1
Williams, JD1
Dougall, HT1
McLay, J1
Jan, CR1
Chen, WC1
Wu, SN1
Tseng, CJ1
Suzuki, H1
Nakamoto, H1
Nemoto, H1
Sugahara, S1
Okada, H1
Marin, R1
Ruilope, LM1
Aljama, P1
Aranda, P1
Segura, J1
Diez, J1
Berger, HH1
Albert, FW1
Salducci, MD1
Chauvet-Monges, AM1
Berland, Y1
Dussol, B1
Elsen, R1
Crevat, A1
Brooks, DP1
Ohlstein, EH1
Contino, LC1
Storer, B1
Pullen, M1
Caltabiano, M1
Nambi, P1
McNally, PG2
Baker, F2
Mistry, N3
Walls, J3
Feehally, J3
Wilson, PD1
Hartz, PA1
Rodicio Díaz, JL1
Lheureux, P1
Askenasi, R1
Gangi, D1
Laher, MS1
Kelly, JG1
Doyle, GD2
Carmody, M2
Donohoe, JF1
Greb, H2
Volz, M2
Donohue, J1
Laher, M1
Abernethy, DR1
Kiberd, BA1
Soupart, A1
Decaux, G1
Igarashi, N1
Shub, C1
Vlietstra, RE1
McGoon, MD1
Loirat, C1
Horsburgh, T1
Taylor, J1
Veitch, PS1
Bell, PR1
Kwan, JT1
Foxall, PJ1
Townend, JN1
Bending, MR1
Eisinger, AJ1
Lee, SM1
Michael, UF1
Aronoff, GR1
Sloan, RS1
Boelaert, J1
Valcke, Y1
Dammekens, H1
De Vriese, G1
Ahr, G1
Schurgers, M1
Daneels, R1
Bogaert, MG1
Krog, M1
Ejerblad, S1
Johansson, H1
Wilander, E1
Bortolotti, M1
Trisolino, G1
Barbara, L1
Lloret, J1
Vila, A1
Puig, X1
Monmany, J1
Muñoz, J1
More, J1
Kuhlmann, J1
Kleinbloesem, CH1
van Brummelen, P1
van Harten, J1
Danhof, M1
Breimer, DD1
Bursztyn, M1
Grossman, E1
Rosenthal, T1
Moreira, J1
Barata, JD1
Olias, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Allopurinol on Malondialdehyde, Nitric Oxide, Kidney Injury Molecule-1 Urine Levels, Resistive Index and Renal Elastography in Kidney Stone Patients After Extra Corporeal Shockwave Lithotripsy[NCT05414669]Phase 435 participants (Actual)Interventional2020-08-06Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for nifedipine and Kidney Diseases

ArticleYear
Lessons from large interventional trials on antihypertensive therapy in chronic renal disease.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2002, Volume: 17 Suppl 11

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Chronic Disease; Clini

2002
[NICE-Combi study: effect of nifedipine in combination with an angiotensin II receptor blocker on BP control and renal protection].
    Drugs, 2006, Volume: 66 Spec No 1

    Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Doubl

2006
Pharmacological treatment of renal parenchymal hypertension.
    Contributions to nephrology, 1994, Volume: 106

    Topics: Antihypertensive Agents; Captopril; Humans; Hypertension, Renal; Incidence; Kidney Diseases; Models,

1994
A comparative review of the adverse effects of calcium antagonists.
    Drug safety, 1996, Volume: 15, Issue:2

    Topics: Arrhythmias, Cardiac; Calcium Channel Blockers; Cardiovascular System; Endocrine System Diseases; Ga

1996
The pharmacokinetic profile of amlodipine.
    American heart journal, 1989, Volume: 118, Issue:5 Pt 2

    Topics: Administration, Oral; Aging; Amlodipine; Angina Pectoris; Animals; Biological Availability; Calcium

1989
Selection of optimal drug therapy for the patient with angina pectoris.
    Mayo Clinic proceedings, 1985, Volume: 60, Issue:8

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Arrhythmias, Cardiac; Blood Pressure; Calcium Channel

1985
[Arterial hypertension in the newborn infant. Etiologies. Treatment].
    Archives francaises de pediatrie, 1988, Volume: 45, Issue:4

    Topics: Acebutolol; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Endoc

1988

Trials

7 trials available for nifedipine and Kidney Diseases

ArticleYear
[Effect of Jingui Shenqi pill combined with nifedipine for the treatment of elderly hypertensive patients with spleen-kidney Yang deficiency syndrome].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2015, Volume: 40, Issue:24

    Topics: Aged; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Humans; Hypertension; Kidney Disease

2015
Pharmacokinetic profile of nifedipine GITS in hypertensive patients with chronic renal impairment.
    Drugs, 1994, Volume: 48 Suppl 1

    Topics: Administration, Oral; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Kidney Diseases; Mal

1994
Protective effects of nifedipine and allopurinol on high energy shock wave induced acute changes of renal function.
    The Journal of urology, 1995, Volume: 153, Issue:3 Pt 1

    Topics: Adolescent; Adult; Allopurinol; Female; Humans; Kidney Calculi; Kidney Diseases; Kidney Function Tes

1995
A random comparison of fosinopril and nifedipine GITS in patients with primary renal disease.
    Journal of hypertension, 2001, Volume: 19, Issue:10

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Del

2001
Nifedipine in the treatment of renal colic.
    Methods and findings in experimental and clinical pharmacology, 1986, Volume: 8, Issue:9

    Topics: Adult; Blood Pressure; Colic; Female; Heart Rate; Humans; Kidney Diseases; Male; Nifedipine; Pain

1986
Effects of verapamil, diltiazem, and nifedipine on plasma levels and renal excretion of digitoxin.
    Clinical pharmacology and therapeutics, 1985, Volume: 38, Issue:6

    Topics: Aged; Benzazepines; Clinical Trials as Topic; Digitoxin; Diltiazem; Drug Interactions; Drug Therapy,

1985
Nifedipine: influence of renal function on pharmacokinetic/hemodynamic relationship.
    Clinical pharmacology and therapeutics, 1985, Volume: 37, Issue:5

    Topics: Administration, Oral; Adult; Biological Availability; Blood Pressure; Chromatography, High Pressure

1985

Other Studies

46 other studies available for nifedipine and Kidney Diseases

ArticleYear
Hypertensive crisis with 2 target organ impairment induced by glycyrrhizin: A case report.
    Medicine, 2018, Volume: 97, Issue:11

    Topics: Anti-Inflammatory Agents; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Cholangitis;

2018
Molecular basis of the counteraction by calcium channel blockers of cyclosporine nephrotoxicity.
    American journal of physiology. Renal physiology, 2018, 09-01, Volume: 315, Issue:3

    Topics: Animals; Biomarkers; Blood Urea Nitrogen; Calcium Channel Blockers; Collagen Type IV; Creatinine; Cy

2018
8-Br-cADPR, a TRPM2 ion channel antagonist, inhibits renal ischemia-reperfusion injury.
    Journal of cellular physiology, 2019, Volume: 234, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Blood Urea Nitrogen; Calcium Channel Blockers; Catalas

2019
Protective effect of selected calcium channel blockers and prednisolone, a phospholipase-A2 inhibitor, against gentamicin and carbon tetrachloride-induced nephrotoxicity.
    Human & experimental toxicology, 2014, Volume: 33, Issue:8

    Topics: Animals; Antioxidants; Biomarkers; Calcium Channel Blockers; Carbon Tetrachloride; Cytoprotection; D

2014
Barnidipine ameliorates the vascular and renal injury in L-NAME-induced hypertensive rats.
    European journal of pharmacology, 2015, Oct-05, Volume: 764

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cytoprotection; Disease

2015
Klebsiella septicemia presenting as renal subcapsular abscess and hypertension in a neonate.
    Indian pediatrics, 2008, Volume: 45, Issue:8

    Topics: Female; Humans; Hypertension; Infant, Newborn; Kidney Diseases; Klebsiella Infections; Nifedipine; T

2008
Effects of combination therapy with angiotensin II type I receptor blockers and calcium channel blockers on renal function in hypertensive patients/a retrospective, "real-world" comparative study.
    Arzneimittel-Forschung, 2010, Volume: 60, Issue:2

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Creatinine; Dih

2010
Antihypertensive efficacy of Melothria maderaspatana leaf extract on sham-operated and uninephrectomized DOCA-salt hypertensive rats.
    Journal of basic and clinical physiology and pharmacology, 2010, Volume: 21, Issue:1

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Cucurbitac

2010
[CCB uptitration is superior to ARB uptitration in CKD patients who do not reach target blood pressure with ARB/CCB combined therapy].
    Nihon Jinzo Gakkai shi, 2010, Volume: 52, Issue:7

    Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Calcium Channel Blockers; Chro

2010
Vasodilator agents protect against indinavir nephrotoxicity.
    Antiviral therapy, 2003, Volume: 8, Issue:4

    Topics: Animals; Arginine; HIV Protease Inhibitors; Indinavir; Kidney Diseases; Kidney Function Tests; Magne

2003
Acute renal colic.
    The New England journal of medicine, 2004, Jun-03, Volume: 350, Issue:23

    Topics: Acute Disease; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blo

2004
Nifedipine attenuates changes in nitric oxide levels, renal oxidative stress, and nephrotoxicity induced by cyclosporine.
    Renal failure, 2005, Volume: 27, Issue:4

    Topics: Analysis of Variance; Animals; Biopsy, Needle; Cyclosporine; Disease Models, Animal; Immunohistochem

2005
Blood pressure variability, baroreflex sensitivity and organ damage in spontaneously hypertensive rats treated with various antihypertensive drugs.
    European journal of pharmacology, 2006, Aug-14, Volume: 543, Issue:1-3

    Topics: Animals; Antihypertensive Agents; Aorta; Atenolol; Baroreflex; Biphenyl Compounds; Blood Pressure; C

2006
[Ischemic disease of the kidneys in a patient with morbid obesity: characteristics of the course and diagnostic policy].
    Terapevticheskii arkhiv, 2006, Volume: 78, Issue:5

    Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Diagnosis, Differential; Health Policy; Human

2006
Differential effects of dihydropyridine calcium antagonists on doxorubicin-induced nephrotoxicity in rats.
    Toxicology, 2007, Feb-28, Volume: 231, Issue:1

    Topics: Amlodipine; Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Blood Urea Nitrogen; Calci

2007
Nifedipine-induced renal dysfunction. Alterations in renal hemodynamics.
    The American journal of medicine, 1984, Volume: 77, Issue:5

    Topics: Aged; Humans; Kidney Diseases; Male; Middle Aged; Nifedipine; Norepinephrine; Prostaglandins; Vasoco

1984
Tacrolimus (FK506)-induced nephrotoxicity in spontaneous hypertensive rats.
    The Journal of toxicological sciences, 1994, Volume: 19, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arterioles; Blood Urea Nitrogen; Creatinine; Hypertension; Ki

1994
Effect of nifedipine on tubular handling of uric acid in transplanted kidney on cyclosporine A treatment.
    Nephron, 1995, Volume: 70, Issue:1

    Topics: Adolescent; Adult; Child; Creatinine; Cyclosporine; Delayed-Action Preparations; Drug Therapy, Combi

1995
Effect of nifedipine on kidney and ureteral function after experimental acute unilateral ureteral obstruction.
    Urology, 1993, Volume: 41, Issue:5

    Topics: Animals; Colic; Glomerular Filtration Rate; Kidney; Kidney Diseases; Male; Muscle Contraction; Muscl

1993
Malignant hypertension in children in India.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1996, Volume: 11, Issue:7

    Topics: Adolescent; Angioplasty; Antihypertensive Agents; Child; Child, Preschool; Female; Humans; Hypertens

1996
Effects of a selective adenosine A1 receptor antagonist on the development of cyclosporin nephrotoxicity.
    British journal of pharmacology, 1996, Volume: 117, Issue:5

    Topics: Animals; Blood Pressure; Cyclosporine; Drug Interactions; Glomerular Filtration Rate; Immunosuppress

1996
Nifedipine, verapamil and diltiazem block shock-wave-induced rises in cytosolic calcium in MDCK cells.
    The Chinese journal of physiology, 1998, Dec-31, Volume: 41, Issue:4

    Topics: Adenosine Triphosphate; Animals; Aspartate Aminotransferases; Bradykinin; Calcium; Calcium Channel B

1998
Control of blood pressure and prevention of end-organ damage in patients with accelerated hypertension by combination with arotinolol and extended release nifedipine.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2000, Volume: 23, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Biopsy; Blood Pressure; Calcium Channel Blockers; Creatinine; De

2000
Nilvadipine in hypertension with renal dysfunction.
    Journal of cardiovascular pharmacology, 1992, Volume: 20 Suppl 6

    Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Creatinine; Female; Heart Rate; H

1992
The restoration of ATP synthesis may explain the protective effect of calcium antagonists against cyclosporine A nephrotoxicity.
    Life sciences, 1992, Volume: 50, Issue:26

    Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channels; Cyclosporine; Kidney; Kidney Diseases; M

1992
Effect of nifedipine on cyclosporine A-induced nephrotoxicity, urinary endothelin excretion and renal endothelin receptor number.
    European journal of pharmacology, 1991, Feb-26, Volume: 194, Issue:1

    Topics: Animals; Blood Urea Nitrogen; Creatinine; Cyclosporins; Endothelins; Glomerular Filtration Rate; In

1991
Influence of nifedipine on cyclosporin A nephrotoxicity after unilateral nephrectomy in the spontaneously hypertensive rat.
    Clinical science (London, England : 1979), 1991, Volume: 81, Issue:2

    Topics: Animals; Cyclosporins; Denervation; Female; Glomerular Filtration Rate; Kidney; Kidney Diseases; Nep

1991
Mechanisms of cyclosporine A toxicity in defined cultures of renal tubule epithelia: a role for cysteine proteases.
    Cell biology international reports, 1991, Volume: 15, Issue:12

    Topics: Animals; Calcium; Cell Death; Cells, Cultured; Cyclosporine; Cysteine Endopeptidases; Cysteine Prote

1991
Effect of nifedipine on renal haemodynamics in an animal model of cyclosporin A nephrotoxicity.
    Clinical science (London, England : 1979), 1990, Volume: 79, Issue:3

    Topics: Animals; Cyclosporins; Disease Models, Animal; Female; Glomerular Filtration Rate; Hemodynamics; Kid

1990
[Renal effects of calcium antagonists].
    Revista clinica espanola, 1990, Volume: 186, Issue:3

    Topics: Calcium Channel Blockers; Cyclosporins; Glomerular Filtration Rate; Humans; Kidney Diseases; Natriur

1990
Unreliable effect of nifedipine in relieving renal colic.
    Annals of emergency medicine, 1990, Volume: 19, Issue:7

    Topics: Colic; Humans; Kidney Diseases; Nifedipine

1990
Pharmacokinetics of amlodipine in renal impairment.
    Journal of cardiovascular pharmacology, 1988, Volume: 12 Suppl 7

    Topics: Adult; Aged; Amlodipine; Calcium Channel Blockers; Female; Half-Life; Humans; Kidney Diseases; Male;

1988
Pharmacokinetics of amlodipine in renal impairment.
    European journal of clinical pharmacology, 1989, Volume: 36, Issue:2

    Topics: Adult; Aged; Amlodipine; Calcium Channel Blockers; Female; Half-Life; Humans; Kidney Diseases; Male;

1989
Cyclosporine-induced renal dysfunction in human renal allograft recipients.
    Transplantation, 1989, Volume: 48, Issue:6

    Topics: Cyclosporins; Female; Glomerular Filtration Rate; Humans; Kidney; Kidney Diseases; Kidney Transplant

1989
Nifedipine and amphotericin B nephrotoxicity in the rat.
    Nephron, 1989, Volume: 52, Issue:3

    Topics: Amphotericin B; Animals; Glomerular Filtration Rate; Hemodynamics; Kidney Diseases; Nifedipine; Rats

1989
[The effects of nifedipine on blood pressure and renal function].
    Nihon Jinzo Gakkai shi, 1989, Volume: 31, Issue:4

    Topics: Administration, Oral; Adult; Animals; Blood Pressure; Humans; Hypertension; Kidney; Kidney Diseases;

1989
Does nifedipine ameliorate cyclosporin A nephrotoxicity?
    British medical journal (Clinical research ed.), 1987, Aug-01, Volume: 295, Issue:6593

    Topics: Adult; Cyclosporins; Humans; Hypertension; Kidney; Kidney Diseases; Kidney Transplantation; Middle A

1987
Does nifedipine ameliorate cyclosporin A nephrotoxicity?
    British medical journal (Clinical research ed.), 1987, Oct-03, Volume: 295, Issue:6602

    Topics: Cyclosporins; Humans; Kidney Diseases; Kidney Transplantation; Middle Aged; Nifedipine

1987
The protective effect of nitrendipine on gentamicin acute renal failure in rats.
    Experimental and molecular pathology, 1985, Volume: 43, Issue:1

    Topics: Acute Kidney Injury; Animals; Female; Gentamicins; Hemodynamics; Kidney; Kidney Diseases; Kidney Fun

1985
Nitrendipine kinetics in normal and impaired renal function.
    Clinical pharmacology and therapeutics, 1985, Volume: 38, Issue:2

    Topics: Adult; Aged; Antihypertensive Agents; Biotransformation; Creatinine; Humans; Intestinal Absorption;

1985
Calcium antagonist prevents nephrotoxicity.
    British journal of hospital medicine, 1988, Volume: 40, Issue:1

    Topics: Animals; Cyclosporins; Humans; Kidney; Kidney Diseases; Nifedipine; Rats

1988
Pharmacokinetics of nisoldipine in renal dysfunction.
    European journal of clinical pharmacology, 1988, Volume: 34, Issue:2

    Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Female; Heart Rate; Humans; Kidney Diseases;

1988
Tissue calcification and alkaline phosphatase activity in uraemic rats.
    Scandinavian journal of urology and nephrology, 1988, Volume: 22, Issue:1

    Topics: Alkaline Phosphatase; Animals; Aortic Diseases; Calcinosis; Calcitriol; Cardiomyopathies; Creatinine

1988
Nifedipine in biliary and renal colic.
    JAMA, 1987, Dec-25, Volume: 258, Issue:24

    Topics: Biliary Tract Diseases; Colic; Humans; Kidney Diseases; Nifedipine

1987
Long-acting nifedipine in moderate and severe hypertensive patients with serious concomitant diseases.
    American heart journal, 1985, Volume: 110, Issue:1 Pt 1

    Topics: Adult; Aged; Angina Pectoris; Asthma; Cerebrovascular Disorders; Diabetes Complications; Edema; Fema

1985
Antihypertensive action of calcium blockade in hypertensive patients with chronic renal disease.
    Nephron, 1985, Volume: 41, Issue:4

    Topics: Adult; Aged; Blood Pressure; Chronic Disease; Drug Therapy, Combination; Female; Humans; Hypertensio

1985