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nifedipine and Ischemic Attack, Transient

nifedipine has been researched along with Ischemic Attack, Transient in 28 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Ischemic Attack, Transient: Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)

Research Excerpts

ExcerptRelevanceReference
"026), avoidance of sublingual nifedipine in patients with acute ischemic stroke (97."3.73Improved quality of stroke care for hospitalized Medicare beneficiaries in Michigan. ( Baker, PL; Jacobs, BS; Levine, SR; Mehta, RH; Roychoudhury, C, 2005)
"We examined the efficacy of slow-release, and prolonged diffusion silicone pellets mixed with papaverine hydrochloride in the treatment of cerebral vasospasms following subarachnoid hemorrhage."3.67[Sustained-release pellet of vasodilators--basic experiment]. ( Arimitsu, T; Mori, K; Oda, Y; Okumura, T, 1984)
"Therapy with OSMO-Adalat of patients with AH combination with KPA provides a good hypotensive effect and relieves symptoms of encephalopathy, myocardial ischemia and orthostatic insufficiency in low risk of side effects."2.70[Efficacy of OSMO-Adalat in patients with arterial hypertension in combination with kinked precerebral arteries]. ( Khirmanov, VN; Sorokoumov, VA; Tiurina, TV; Zakharova, IV, 2001)
"Nimodipine was found to be more potent, both in the chamber and in the live dog experiments."2.66Role of calcium antagonists in cerebral arterial spasm. ( Allen, GS, 1985)
"In addition, evolution of cerebral infarction was studied at 6 hours and 12 hours post-occlusion by magnetic resonance imaging (MRI)."1.28[Ca++ antagonist and acute brain ischemia: effects of nilvadipine and nicardipine on middle cerebral artery occlusion in rats]. ( Handa, J; Inubushi, T; Kido, C; Matsuda, M; Morikawa, S; Shiino, A; Susumu, T, 1991)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199013 (46.43)18.7374
1990's8 (28.57)18.2507
2000's6 (21.43)29.6817
2010's1 (3.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Xu, J1
Liu, ZA1
Pei, DS1
Xu, TJ1
El-Abhar, HS1
Shaalan, M1
Barakat, M1
El-Denshary, ES1
Jacobs, BS1
Baker, PL1
Roychoudhury, C1
Mehta, RH1
Levine, SR1
Zhang, QG1
Xu, YL1
Li, HC1
Han, D1
Zhang, GY3
Ellrodt, AG1
Singh, BN1
Kamiya, K2
Weir, B1
Okumura, T1
Oda, Y1
Arimitsu, T1
Mori, K1
Abe, S1
Takagi, T1
Fukuoka, H1
Nagai, H1
Hotta, K1
Wiernsperger, N1
Reves, JG1
Kissin, I1
Lell, WA1
Tosone, S1
Nobile-Orazio, E1
Sterzi, R1
Buscaino, GA1
Tanne, D1
Reicher-Reiss, H1
Boyko, V1
Behar, S1
Li, Y4
Kawamura, S2
Yasui, N2
Shirasawa, M2
Fukasawa, H2
Hongo, K1
Kobayashi, S1
Lee, YJ1
Jy, W1
Horstman, LL1
Janania, J1
Reyes, Y1
Kelley, RE1
Ahn, YS1
Aliev, MA1
Lemeshenko, VA1
Bekbolotova, AK1
Miyazaki, H1
Tanaka, S1
Fujii, Y1
Shimizu, K1
Nagashima, K1
Kamibayashi, M1
Uehara, T1
Okuma, Y1
Nomura, Y1
Pei, L2
Cui, ZC2
Zhu, ZM2
Yan, JZ1
Khirmanov, VN1
Tiurina, TV1
Sorokoumov, VA1
Zakharova, IV1
Allen, GS2
Bahr, AL1
Banghart, SB1
Shiino, A1
Matsuda, M1
Handa, J1
Morikawa, S1
Kido, C1
Inubushi, T1
Susumu, T1
Zabramski, J1
Spetzler, RF1
Bonstelle, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized, Phase III-b, Multi-centre, Open-label, Parallel Study of Enoxaparin (Low Molecular Weight Heparin) Given Concomitantly With Chemotherapy vs Chemotherapy Alone in Patients With Inoperable Gastric and Gastro-oesophageal Cancer[NCT00718354]Phase 3740 participants (Actual)Interventional2008-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for nifedipine and Ischemic Attack, Transient

ArticleYear
Clinical applications of slow channel blocking compounds.
    Pharmacology & therapeutics, 1983, Volume: 23, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Blood Platelets; Blood Vessels; Calcium

1983
Calcium antagonists, cerebral ischemia and vasospasm.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1984, Volume: 11, Issue:2

    Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Cats; Cerebral Arteries; Cerebrovascular Circulat

1984
Calcium entry blockers: uses and implications for anesthesiologists.
    Anesthesiology, 1982, Volume: 57, Issue:6

    Topics: Anesthesia, General; Animals; Arrhythmias, Cardiac; Biotransformation; Calcium Channel Blockers; Cor

1982
Calcium antagonists for the treatment of vasospasm following subarachnoid haemorrhage.
    Neurological research, 1993, Volume: 15, Issue:4

    Topics: Animals; Calcium Channel Blockers; Cerebrovascular Circulation; Diltiazem; Humans; Ischemic Attack,

1993

Trials

4 trials available for nifedipine and Ischemic Attack, Transient

ArticleYear
Calcium antagonists, cerebral ischemia and vasospasm.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1984, Volume: 11, Issue:2

    Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Cats; Cerebral Arteries; Cerebrovascular Circulat

1984
Stroke risk after anterior wall acute myocardial infarction. SPRINT Study Group. Secondary Prevention Reinfarction Israeli Nifedipine Trial.
    The American journal of cardiology, 1995, Oct-15, Volume: 76, Issue:11

    Topics: Aged; Atrial Fibrillation; Cerebrovascular Disorders; Chronic Disease; Female; Follow-Up Studies; Hu

1995
[Efficacy of OSMO-Adalat in patients with arterial hypertension in combination with kinked precerebral arteries].
    Terapevticheskii arkhiv, 2001, Volume: 73, Issue:9

    Topics: Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Carotid Artery Diseases; De

2001
Role of calcium antagonists in cerebral arterial spasm.
    The American journal of cardiology, 1985, Jan-25, Volume: 55, Issue:3

    Topics: Animals; Calcium Channel Blockers; Cerebral Arteries; Clinical Trials as Topic; Dogs; Double-Blind M

1985

Other Studies

21 other studies available for nifedipine and Ischemic Attack, Transient

ArticleYear
Calcium/calmodulin-dependent kinase II facilitated GluR6 subunit serine phosphorylation through GluR6-PSD95-CaMKII signaling module assembly in cerebral ischemia injury.
    Brain research, 2010, Dec-17, Volume: 1366

    Topics: Analysis of Variance; Animals; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Dis

2010
Effect of melatonin and nifedipine on some antioxidant enzymes and different energy fuels in the blood and brain of global ischemic rats.
    Journal of pineal research, 2002, Volume: 33, Issue:2

    Topics: 3-Hydroxybutyric Acid; Animals; Antioxidants; Blood; Brain; Calcium Channel Blockers; Disease Models

2002
Improved quality of stroke care for hospitalized Medicare beneficiaries in Michigan.
    Stroke, 2005, Volume: 36, Issue:6

    Topics: Administration, Sublingual; Aged; Aged, 80 and over; Fee-for-Service Plans; Female; Hospitalization;

2005
NMDA receptor/L-VGCC-dependent expression and AMPA/KA receptor-dependent activation of c-Jun induced by cerebral ischemia in rat hippocampus.
    Neuroscience letters, 2006, May-08, Volume: 398, Issue:3

    Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Carotid Stenosis; Enzyme Activation; Hi

2006
[Effect of Ca2+ antagonists on experimental cerebral vasospasm (author's transl)].
    Neurologia medico-chirurgica, 1980, Volume: 20, Issue:8

    Topics: Animals; Blood Pressure; Calcium; Cinnarizine; Dogs; Dose-Response Relationship, Drug; Intracranial

1980
[Sustained-release pellet of vasodilators--basic experiment].
    No shinkei geka. Neurological surgery, 1984, Volume: 12, Issue:11

    Topics: Delayed-Action Preparations; Diltiazem; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; N

1984
[Clinical and experimental studies on the role of Ca++ in etiology of cerebral vasospasm].
    No shinkei geka. Neurological surgery, 1983, Volume: 11, Issue:11

    Topics: Adult; Aged; Animals; Calcium; Dinoprost; Dogs; Female; Humans; Ischemic Attack, Transient; Male; Mi

1983
[Effect of diltiazem on experimental cerebral vasospasm incomparison with effects of cinnarizine, verapamil and nifedipine].
    No shinkei geka. Neurological surgery, 1983, Volume: 11, Issue:6

    Topics: Animals; Benzazepines; Blood Pressure; Cinnarizine; Diltiazem; Dogs; Dose-Response Relationship, Dru

1983
Focal epicerebral ischemia: post-ischemic tissue oxygenation with and without recirculation.
    Advances in experimental medicine and biology, 1984, Volume: 169

    Topics: Animals; Aspirin; Cats; Cerebrovascular Circulation; Injections, Intravenous; Ischemic Attack, Trans

1984
Cerebral ischaemia after nifedipine treatment.
    British medical journal (Clinical research ed.), 1981, Oct-10, Volume: 283, Issue:6297

    Topics: Aged; Arrhythmias, Cardiac; Female; Humans; Hypertension; Ischemic Attack, Transient; Male; Nifedipi

1981
[Medical treatment of acute disorders of cerebral circulation].
    Acta neurologica. Quaderni, 1980, Volume: 41

    Topics: Aminophylline; Anticoagulants; Antihypertensive Agents; Brain Edema; Cerebrovascular Disorders; Cinn

1980
Therapeutic effects of nilvadipine on rat focal cerebral ischemia.
    Experimental brain research, 1994, Volume: 99, Issue:1

    Topics: Animals; Blood Pressure; Brain; Calcium Channel Blockers; Cerebral Arteries; Cerebral Infarction; Is

1994
Elevated platelet microparticles in transient ischemic attacks, lacunar infarcts, and multiinfarct dementias.
    Thrombosis research, 1993, Nov-15, Volume: 72, Issue:4

    Topics: Adult; Aged; Alzheimer Disease; Blood Platelets; Cerebral Infarction; Dementia, Multi-Infarct; Femal

1993
[Effect of transient cerebral ischemia on the synthesis of prostacyclin in dogs with arterial hypertension].
    Biulleten' eksperimental'noi biologii i meditsiny, 1997, Volume: 124, Issue:9

    Topics: Animals; Calcium Channel Blockers; Coronary Thrombosis; Dogs; Epoprostenol; Hypertension; Ischemic A

1997
Effects of treatment with nilvadipine on cerebral ischemia in rats.
    The Tohoku journal of experimental medicine, 1998, Volume: 185, Issue:4

    Topics: Animals; Antihypertensive Agents; Brain; Calcium Channel Blockers; Cerebral Infarction; Hypertension

1998
Neuroprotective effects of a dihydropyridine derivative, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarbox ylic acid methyl 6-(5-phenyl-3-pyrazolyloxy)hexyl ester (CV-159), on rat ischemic brain injury.
    Life sciences, 1999, Volume: 64, Issue:10

    Topics: Animals; Body Temperature; Brain Edema; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Prote

1999
Mechanisms of regulation of tyrosine phosphorylation of NMDA receptor subunit 2B after cerebral ischemia/reperfusion.
    Acta pharmacologica Sinica, 2000, Volume: 21, Issue:8

    Topics: Animals; Calcium Channel Blockers; Genistein; Gerbillinae; Hippocampus; Ischemic Attack, Transient;

2000
Changes and mechanisms of protein-tyrosine kinase and protein-tyrosine phosphatase activities after brain ischemia/reperfusion.
    Acta pharmacologica Sinica, 2000, Volume: 21, Issue:8

    Topics: Animals; Calcium Channel Blockers; Gerbillinae; Hippocampus; Ischemic Attack, Transient; Ketamine; N

2000
Effects of nifedipine on artificially induced femoral and basilar artery contraction in vitro and reversal of acute and chronic vertebral basilar spasm by orally administered nifedipine in dogs.
    Neuroradiology, 1978, Volume: 16

    Topics: Acute Disease; Animals; Basilar Artery; Chronic Disease; Dogs; Femoral Artery; Ischemic Attack, Tran

1978
[Ca++ antagonist and acute brain ischemia: effects of nilvadipine and nicardipine on middle cerebral artery occlusion in rats].
    Nihon geka hokan. Archiv fur japanische Chirurgie, 1991, Jan-01, Volume: 60, Issue:1

    Topics: Acute Disease; Animals; Calcium Channel Blockers; Cerebral Infarction; Constriction; Ischemic Attack

1991
Chronic cerebral vasospasm: effect of calcium antagonists.
    Neurosurgery, 1986, Volume: 18, Issue:2

    Topics: Animals; Cerebral Angiography; Chronic Disease; Disease Models, Animal; Dogs; Injections; Ischemic A

1986