nifedipine has been researched along with Iron Overload in 3 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Iron Overload: An excessive accumulation of iron in the body due to a greater than normal absorption of iron from the gastrointestinal tract or from parenteral injection. This may arise from idiopathic hemochromatosis, excessive iron intake, chronic alcoholism, certain types of refractory anemia, or transfusional hemosiderosis. (From Churchill's Illustrated Medical Dictionary, 1989)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, L | 1 |
| Lin, X | 1 |
| Pornprasert, S | 1 |
| Lü, X | 1 |
| Ran, B | 1 |
| Lin, Y | 1 |
| Ludwiczek, S | 1 |
| Theurl, I | 1 |
| Muckenthaler, MU | 1 |
| Jakab, M | 1 |
| Mair, SM | 1 |
| Theurl, M | 1 |
| Kiss, J | 1 |
| Paulmichl, M | 1 |
| Hentze, MW | 1 |
| Ritter, M | 1 |
| Weiss, G | 1 |
| Anghileri, LJ | 1 |
| Thouvenot, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Trial of Oral Nifedipine for the Treatment of Iron Overload[NCT00712738] | Phase 1 | 6 participants (Actual) | Interventional | 2008-06-20 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for nifedipine and Iron Overload
| Article | Year |
|---|---|
L-type calcium channel blockers decrease the iron overload-mediated oxidative stress in renal epithelial cells by reducing iron accumulation.
Topics: Apoptosis; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cation Transport Proteins; E | 2020 |
Ca2+ channel blockers reverse iron overload by a new mechanism via divalent metal transporter-1.
Topics: Animals; Biological Transport, Active; Calcium Channel Blockers; Cation Transport Proteins; Chloroce | 2007 |
ATP in iron overload-induced intracellular calcium changes.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channels; Carcinoma, Ehrlich Tumor; Deferoxamine; | 1998 |