nifedipine has been researched along with Intraocular Pressure in 37 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Intraocular Pressure: The pressure of the fluids in the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Forty patients without eye disease, undergoing elective nonophthalmic surgery, were studied to evaluate the efficacy of sublingual nifedipine in attenuating the intraocular pressure response to succinylcholine administration, laryngoscopy and intubation." | 9.06 | Nifedipine attenuates the intraocular pressure response to intubation following succinylcholine. ( Batra, YK; Indu, B; Puri, GD; Singh, H, 1989) |
| "The effect of a nifedipine induced reduction in systemic blood pressure on pulse amplitude (PA) as assessed with pneumotonometry and fundus pulsation amplitude (FPA), as measured with laser interferometry was investigated in 16 untreated patients with moderate to severe systemic hypertension (mean arterial pressure 123 (SD 12) mm Hg)." | 7.73 | Effect of a nifedipine induced reduction in blood pressure on the association between ocular pulse amplitude and ocular fundus pulsation amplitude in systemic hypertension. ( Bayerle-Eder, M; Gasic, S; Kolodjaschna, J; Polska, E; Schmetterer, L; Wolzt, M, 2005) |
| "To evaluate the possible role of calcium channel blocker on changes in aqueous flare and intraocular pressure induced by prostaglandin E2 (PGE2) in pigmented rabbits, we examined the effects of nilvadipine and nicardipine (calcium channel blockers)." | 7.70 | Nilvadipine inhibits acute rise of aqueous flare and intraocular pressure induced by prostaglandin E2 in pigmented rabbits. ( Hayasaka, S; Hiraki, S; Zhang, XY, 1998) |
| "To investigate ocular hemodynamic and visual function changes in patients with normal-tension glaucoma after treatment with a calcium channel blocker (nifedipine)." | 7.69 | Hemodynamic and visual function effects of oral nifedipine in patients with normal-tension glaucoma. ( Cantor, LB; Evans, DW; Harris, A; Martin, B, 1997) |
| "We studied the effects of nifedipine, a calcium antagonist, given intravenously and orally, on intraocular pressure in six normal volunteers." | 7.67 | Effect of the calcium antagonist nifedipine on intraocular pressure in normal subjects. ( Kelly, SP; Walley, TJ, 1988) |
| " The current investigations clarified the efficiency of this novel and unique NF loaded in situ gel for the control of the IOP compared to the conventional ophthalmic dosage forms." | 5.62 | Repurposing of nifedipine loaded in situ ophthalmic gel as a novel approach for glaucoma treatment. ( Ahmed, KA; El-Feky, YA; El-Telbany, DFA; El-Telbany, RFA; Fares, AR; Zayed, G, 2021) |
| " The time-course of the ocular effects of topical verapamil and nifedipine as well as the dose-response relationship, were studied in conscious, normotensive rabbits." | 5.29 | The topical application of verapamil and nifedipine lowers intraocular pressure in conscious rabbits. ( Garrido, M; Martínez de Ibarreta, MJ; Santafé, J; Segarra, J, 1993) |
| "To study the 3-year effect of oral nilvadipine, a calcium antagonist, on visual field performance and ocular circulation in open-angle glaucoma (OAG) with low-normal intraocular pressure (IOP)." | 5.13 | A placebo-controlled 3-year study of a calcium blocker on visual field and ocular circulation in glaucoma with low-normal pressure. ( Araie, M; Hasegawa, T; Koseki, N; Nagahara, M; Tamaki, Y; Tomidokoro, A; Yamamoto, S, 2008) |
| "To study the effects of nilvadipine, a Ca2+ antagonist, on tissue circulation in the optic nerve head (ONH), choroid, and retina in rabbits and on the ONH circulation in normal tension glaucoma (NTG) patients." | 5.09 | Effects of nilvadipine, a calcium antagonist, on rabbit ocular circulation and optic nerve head circulation in NTG subjects. ( Araie, M; Nagahara, M; Sugiyama, T; Tamaki, Y; Tomita, K, 1999) |
| "Forty patients without eye disease, undergoing elective nonophthalmic surgery, were studied to evaluate the efficacy of sublingual nifedipine in attenuating the intraocular pressure response to succinylcholine administration, laryngoscopy and intubation." | 5.06 | Nifedipine attenuates the intraocular pressure response to intubation following succinylcholine. ( Batra, YK; Indu, B; Puri, GD; Singh, H, 1989) |
| "To study the time course of changes in circulation in the optic nerve head (ONH) after acute reduction in intraocular pressure (IOP) and to evaluate the effects of a calcium antagonist, a nitric oxide synthetase (NOS) inhibitor, indomethacin, and sympathetic nerve amputation on the changes in ONH circulation after reduction of IOP." | 3.73 | Time course of changes in optic nerve head circulation after acute reduction in intraocular pressure. ( Araie, M; Takayama, J; Tamaki, Y; Tomidokoro, A, 2005) |
| "The effect of a nifedipine induced reduction in systemic blood pressure on pulse amplitude (PA) as assessed with pneumotonometry and fundus pulsation amplitude (FPA), as measured with laser interferometry was investigated in 16 untreated patients with moderate to severe systemic hypertension (mean arterial pressure 123 (SD 12) mm Hg)." | 3.73 | Effect of a nifedipine induced reduction in blood pressure on the association between ocular pulse amplitude and ocular fundus pulsation amplitude in systemic hypertension. ( Bayerle-Eder, M; Gasic, S; Kolodjaschna, J; Polska, E; Schmetterer, L; Wolzt, M, 2005) |
| "To investigate the time course of changes in optic nerve head (ONH) circulation after an acute increase in intraocular pressure (IOP), by using the laser speckle method, and to evaluate the effects of a calcium antagonist, the nitric oxide synthetase inhibitor, indomethacin, or sympathetic nerve amputation on the response in ONH circulation after an acute increase in IOP." | 3.72 | Time course of the change in optic nerve head circulation after an acute increase in intraocular pressure. ( Araie, M; Fukaya, Y; Hosokawa, T; Ishii, K; Takayama, J; Tamaki, Y; Tomidokoro, A, 2003) |
| "To determine whether topical application of flunarizine reduces intraocular pressure (IOP) and acts as a retinal neuroprotectant and to compare the effectiveness of flunarizine with betaxolol and nifedipine at reducing the influx of calcium and sodium." | 3.71 | Topical flunarizine reduces IOP and protects the retina against ischemia-excitotoxicity. ( Chidlow, G; Cupido, A; Melena, J; Osborne, NN; Wood, JP, 2002) |
| "To evaluate the possible role of calcium channel blocker on changes in aqueous flare and intraocular pressure induced by prostaglandin E2 (PGE2) in pigmented rabbits, we examined the effects of nilvadipine and nicardipine (calcium channel blockers)." | 3.70 | Nilvadipine inhibits acute rise of aqueous flare and intraocular pressure induced by prostaglandin E2 in pigmented rabbits. ( Hayasaka, S; Hiraki, S; Zhang, XY, 1998) |
| "OPA was determined using the Langham ocular blood flow (OBF) system, applanation intraocular pressure (IOP), systemic blood pressure, and heart rate were measured, and ocular perfusion pressure was calculated before and after exercise and smoking in 12 otherwise nonsmoking, healthy volunteers and prior to and for 3 months after initiation of nifedipine therapy in 32 LTG patients with and without a vasospastic reaction as manifested by a nailfold capillary blood flow test." | 3.69 | Influence of physical exercise and nifedipine on ocular pulse amplitude. ( Hessemer, V; Mittag, TW; Pavlovic, S; Schmidt, KG, 1996) |
| "This pilot study used color Doppler imaging to investigate the effects of nifedipine on the posterior ocular blood flow of patients with glaucoma progression at normal intraocular pressures." | 3.69 | A color Doppler analysis of nifedipine-induced posterior ocular blood flow changes in open-angle glaucoma. ( Bond, JB; Chang, WJ; Harris, A; Moster, MR; Schmidt, CM; Sergott, RC; Wilson, RP, 1997) |
| "To investigate ocular hemodynamic and visual function changes in patients with normal-tension glaucoma after treatment with a calcium channel blocker (nifedipine)." | 3.69 | Hemodynamic and visual function effects of oral nifedipine in patients with normal-tension glaucoma. ( Cantor, LB; Evans, DW; Harris, A; Martin, B, 1997) |
| "Topical administration of three different calcium channel blockers (verapamil hydrochloride, diltiazem hydrochloride, or nifedipine) increased intraocular pressure transiently in rabbits." | 3.67 | Elevation of intraocular pressure by calcium channel blockers. ( Beatty, JF; Becker, B; Krupin, T; Nichols, PF, 1984) |
| " The current investigations clarified the efficiency of this novel and unique NF loaded in situ gel for the control of the IOP compared to the conventional ophthalmic dosage forms." | 1.62 | Repurposing of nifedipine loaded in situ ophthalmic gel as a novel approach for glaucoma treatment. ( Ahmed, KA; El-Feky, YA; El-Telbany, DFA; El-Telbany, RFA; Fares, AR; Zayed, G, 2021) |
| "Bilateral optic disc edema, macular star, and preretinal hemorrhages were found in fundoscopic examination." | 1.40 | Diagnosis of malignant hypertension with ocular examination: a child case. ( Caça, I; Cınar, Y; Mehmet Türkcü, F; Sahin, A; Yıldırım, A; Yüksel, H, 2014) |
| "The intraocular pressure was also measured at 5-day intervals." | 1.30 | Effect of long-term topical betaxolol on tissue circulation in the iris and optic nerve head. ( Araie, M; Muta, K, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (18.92) | 18.7374 |
| 1990's | 17 (45.95) | 18.2507 |
| 2000's | 7 (18.92) | 29.6817 |
| 2010's | 5 (13.51) | 24.3611 |
| 2020's | 1 (2.70) | 2.80 |
| Authors | Studies |
|---|---|
| El-Feky, YA | 1 |
| Fares, AR | 1 |
| Zayed, G | 1 |
| El-Telbany, RFA | 1 |
| Ahmed, KA | 1 |
| El-Telbany, DFA | 1 |
| Yıldırım, A | 1 |
| Mehmet Türkcü, F | 1 |
| Yüksel, H | 1 |
| Sahin, A | 1 |
| Cınar, Y | 1 |
| Caça, I | 1 |
| Fang, L | 1 |
| Turtschi, S | 1 |
| Mozaffarieh, M | 1 |
| Koseki, N | 1 |
| Araie, M | 8 |
| Tomidokoro, A | 4 |
| Nagahara, M | 2 |
| Hasegawa, T | 1 |
| Tamaki, Y | 4 |
| Yamamoto, S | 1 |
| Schmidl, D | 1 |
| Prinz, A | 1 |
| Kolodjaschna, J | 2 |
| Polska, E | 2 |
| Luksch, A | 1 |
| Fuchsjager-Mayrl, G | 1 |
| Garhofer, G | 1 |
| Schmetterer, L | 3 |
| Mayama, C | 1 |
| Ishii, K | 2 |
| Ota, T | 1 |
| Takayama, J | 2 |
| Fukaya, Y | 1 |
| Hosokawa, T | 1 |
| Bayerle-Eder, M | 1 |
| Wolzt, M | 2 |
| Gasic, S | 1 |
| Monica, ML | 1 |
| Hesse, RJ | 1 |
| Messerli, FH | 1 |
| Beatty, JF | 1 |
| Krupin, T | 1 |
| Nichols, PF | 1 |
| Becker, B | 1 |
| Segarra, J | 1 |
| Santafé, J | 1 |
| Garrido, M | 1 |
| Martínez de Ibarreta, MJ | 1 |
| Netland, PA | 1 |
| Chaturvedi, N | 1 |
| Dreyer, EB | 1 |
| Liu, S | 1 |
| Araujo, SV | 1 |
| Spaeth, GL | 1 |
| Katz, LJ | 1 |
| Smith, M | 1 |
| Schmidt, KG | 2 |
| Mittag, TW | 2 |
| Pavlovic, S | 1 |
| Hessemer, V | 1 |
| Geyer, O | 2 |
| Neudorfer, M | 1 |
| Kessler, A | 1 |
| Firsteter, E | 1 |
| Lazar, M | 1 |
| Almog, Y | 1 |
| Muta, K | 1 |
| Wilson, RP | 1 |
| Chang, WJ | 1 |
| Sergott, RC | 1 |
| Moster, MR | 1 |
| Schmidt, CM | 1 |
| Bond, JB | 1 |
| Harris, A | 2 |
| von Rückmann, A | 1 |
| Evans, DW | 1 |
| Cantor, LB | 1 |
| Martin, B | 1 |
| Zhang, XY | 1 |
| Hiraki, S | 1 |
| Hayasaka, S | 1 |
| Cioffi, GA | 1 |
| Yamamoto, T | 2 |
| Niwa, Y | 2 |
| Kawakami, H | 1 |
| Kitazawa, Y | 4 |
| Tomita, K | 1 |
| Sugiyama, T | 3 |
| Shimazawa, M | 2 |
| Azuma, I | 1 |
| Iwakura, Y | 1 |
| Watari, M | 1 |
| Sakai, T | 1 |
| Hara, H | 2 |
| Tomita, G | 1 |
| Shinohara, H | 1 |
| Hayashi, N | 1 |
| Toriu, N | 1 |
| Sasaoka, M | 1 |
| Rainer, G | 1 |
| Kiss, B | 1 |
| Dallinger, S | 1 |
| Findl, O | 1 |
| Georgopoulos, M | 1 |
| Vass, C | 1 |
| Menapace, R | 1 |
| Polak, K | 1 |
| Eichler, HG | 1 |
| Osborne, NN | 1 |
| Wood, JP | 1 |
| Cupido, A | 1 |
| Melena, J | 1 |
| Chidlow, G | 1 |
| Andersson, SE | 1 |
| Le Greves, P | 1 |
| Lumme, P | 1 |
| Tuulonen, A | 1 |
| Airaksinen, PJ | 1 |
| Alanko, HI | 1 |
| Indu, B | 1 |
| Batra, YK | 1 |
| Puri, GD | 1 |
| Singh, H | 1 |
| Shirai, H | 2 |
| Go, FJ | 2 |
| Asano, K | 1 |
| Kelly, SP | 1 |
| Walley, TJ | 1 |
| Schnell, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Choroidal Blood Flow Regulation During Isometric Exercise: Effects of Ca2+-Channel Blockade[NCT00280462] | 21 participants (Actual) | Interventional | 2005-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for nifedipine and Intraocular Pressure
| Article | Year |
|---|---|
[Basic and clinical studies of pressure-independent damaging factors of open angle glaucoma].
Topics: Animals; Calcium Channel Blockers; Glaucoma, Open-Angle; Haplorhini; Humans; Intraocular Pressure; M | 2011 |
8 trials available for nifedipine and Intraocular Pressure
| Article | Year |
|---|---|
A placebo-controlled 3-year study of a calcium blocker on visual field and ocular circulation in glaucoma with low-normal pressure.
Topics: Administration, Oral; Blood Pressure; Calcium Channel Blockers; Choroid; Double-Blind Method; Female | 2008 |
Effect of nifedipine on choroidal blood flow regulation during isometric exercise.
Topics: Adult; Blood Flow Velocity; Blood Pressure; Body Constitution; Calcium Channel Blockers; Calcium Cha | 2012 |
Lack of effect of calcium channel blockers on open-angle glaucoma.
Topics: Aged; Calcium Channel Blockers; Diltiazem; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Middl | 1996 |
The effect of nilvadipine, a calcium-channel blocker, on the hemodynamics of retrobulbar vessels in normal-tension glaucoma.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Blood Flow Velocity; Blood Pressure; Calcium C | 1998 |
Effects of nilvadipine, a calcium antagonist, on rabbit ocular circulation and optic nerve head circulation in NTG subjects.
Topics: Adult; Aged; Animals; Blood Flow Velocity; Calcium Channel Blockers; Double-Blind Method; Eye; Femal | 1999 |
Changes in optic nerve head blood flow and retrobular hemodynamics following calcium-channel blocker treatment of normal-tension glaucoma.
Topics: Adult; Aged; Aged, 80 and over; Blood Flow Velocity; Calcium Channel Blockers; Chronic Disease; Cili | 1999 |
A double masked placebo controlled study on the effect of nifedipine on optic nerve blood flow and visual field function in patients with open angle glaucoma.
Topics: Administration, Oral; Blood Flow Velocity; Calcium Channel Blockers; Fundus Oculi; Glaucoma, Open-An | 2001 |
Nifedipine attenuates the intraocular pressure response to intubation following succinylcholine.
Topics: Adult; Anesthesia, Intravenous; Blood Pressure; Female; Humans; Intraocular Pressure; Intubation, In | 1989 |
28 other studies available for nifedipine and Intraocular Pressure
| Article | Year |
|---|---|
Repurposing of nifedipine loaded in situ ophthalmic gel as a novel approach for glaucoma treatment.
Topics: Administration, Ophthalmic; Animals; Calcium Channel Blockers; Chemistry, Pharmaceutical; Delayed-Ac | 2021 |
Diagnosis of malignant hypertension with ocular examination: a child case.
Topics: Antihypertensive Agents; Blood Pressure; Child; Doxazosin; Drug Therapy, Combination; Enalapril; Fem | 2014 |
The effect of nifedipine on retinal venous pressure of glaucoma patients with the Flammer-Syndrome.
Topics: Administration, Oral; Aged; Blood Flow Velocity; Blood Pressure; Calcium Channel Blockers; Endotheli | 2015 |
Changes in optic nerve head circulation in response to vasoactive agents: intereye comparison in monkeys with experimental unilateral glaucoma.
Topics: Animals; Arginine; Blood Circulation; Blood Flow Velocity; Calcium Channel Blockers; Disease Models, | 2012 |
Time course of the change in optic nerve head circulation after an acute increase in intraocular pressure.
Topics: Animals; Blood Circulation; Blood Flow Velocity; Calcium Channel Blockers; Indomethacin; Intraocular | 2003 |
Time course of changes in optic nerve head circulation after acute reduction in intraocular pressure.
Topics: Acute Disease; Animals; Blood Circulation; Blood Circulation Time; Blood Flow Velocity; Calcium Chan | 2005 |
Effect of a nifedipine induced reduction in blood pressure on the association between ocular pulse amplitude and ocular fundus pulsation amplitude in systemic hypertension.
Topics: Aged; Blood Pressure; Elasticity; Eye; Female; Heart Rate; Humans; Hypertension; Intraocular Pressur | 2005 |
The effect of a calcium-channel blocking agent on intraocular pressure.
Topics: Adult; Calcium Channel Blockers; Female; Humans; Intraocular Pressure; Male; Middle Aged; Nifedipine | 1983 |
Elevation of intraocular pressure by calcium channel blockers.
Topics: Administration, Oral; Administration, Topical; Animals; Aqueous Humor; Ascorbic Acid; Calcium Channe | 1984 |
The topical application of verapamil and nifedipine lowers intraocular pressure in conscious rabbits.
Topics: Administration, Topical; Animals; Aqueous Humor; Dose-Response Relationship, Drug; Intraocular Press | 1993 |
Calcium channel blockers in the management of low-tension and open-angle glaucoma.
Topics: Administration, Oral; Aged; Aged, 80 and over; Calcium Channel Blockers; Diltiazem; Female; Follow-U | 1993 |
Influence of physical exercise and nifedipine on ocular pulse amplitude.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Choroid; Exercise; Female; Heart Rate; Humans; Intr | 1996 |
Effect of oral nifedipine on ocular blood flow in patients with low tension glaucoma.
Topics: Administration, Oral; Aged; Calcium Channel Blockers; Ciliary Body; Female; Glaucoma, Open-Angle; He | 1996 |
Effect of long-term topical betaxolol on tissue circulation in the iris and optic nerve head.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Betaxolol; Blood Flow Velocity; Blood | 1997 |
A color Doppler analysis of nifedipine-induced posterior ocular blood flow changes in open-angle glaucoma.
Topics: Adult; Aged; Aged, 80 and over; Blood Flow Velocity; Calcium Channel Blockers; Delayed-Action Prepar | 1997 |
[Effect of nifedipine on ocular pulse amplitude in normal pressure glaucoma].
Topics: Administration, Oral; Adult; Blood Flow Velocity; Calcium Channel Blockers; Choroid; Dose-Response R | 1997 |
Hemodynamic and visual function effects of oral nifedipine in patients with normal-tension glaucoma.
Topics: Administration, Oral; Calcium Channel Blockers; Ciliary Arteries; Contrast Sensitivity; Eye; Female; | 1997 |
Nilvadipine inhibits acute rise of aqueous flare and intraocular pressure induced by prostaglandin E2 in pigmented rabbits.
Topics: Animals; Anterior Eye Segment; Aqueous Humor; Calcium Channel Blockers; Dinoprostone; Dose-Response | 1998 |
Three assumptions: ocular blood flow and glaucoma.
Topics: Blood Flow Velocity; Calcium Channel Blockers; Ciliary Arteries; Color Perception; Glaucoma, Open-An | 1998 |
Effect of lomerizine, a new Ca(2+)channel blocker, on the microcirculation in the optic nerve head in conscious rabbits: a study using a laser speckle technique.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Calcium Channel Blockers; Consciousness; Heart Rate; I | 1999 |
Effects of lomerizine, a novel Ca2+ channel blocker, on the normal and endothelin-1-disturbed circulation in the optic nerve head of rabbits.
Topics: Animals; Blood Circulation; Blood Flow Velocity; Blood Pressure; Calcium Channel Blockers; Ciliary A | 2001 |
Topical flunarizine reduces IOP and protects the retina against ischemia-excitotoxicity.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Betaxolol; Calcium; Calcium Channel B | 2002 |
Ruthenium red and capsaicin induce a neurogenic inflammatory response in the rabbit eye: effects of omega-conotoxin GVIA and tetrodotoxin.
Topics: Animals; Aqueous Humor; Calcitonin Gene-Related Peptide; Calcium Channel Blockers; Capsaicin; Eye; F | 1991 |
Neuroretinal rim area in low tension glaucoma: effect of nifedipine and acetazolamide compared to no treatment.
Topics: Acetazolamide; Aged; Blood Pressure; Female; Follow-Up Studies; Glaucoma, Open-Angle; Heart Rate; Hu | 1991 |
The effect of Ca2(+) -antagonist on visual field in low-tension glaucoma.
Topics: Administration, Oral; Blood Pressure; Cold Temperature; Female; Follow-Up Studies; Glaucoma; Heart R | 1989 |
[The effects of Ca2+-antagonist on visual field in low tension glaucoma].
Topics: Administration, Oral; Adult; Aged; Blood Pressure; Female; Glaucoma; Humans; Intraocular Pressure; M | 1988 |
Effect of the calcium antagonist nifedipine on intraocular pressure in normal subjects.
Topics: Administration, Oral; Adult; Blood Pressure; Female; Forearm; Humans; Injections, Intravenous; Intra | 1988 |
[Behavior of intraocular pressure in healthy subjects and glaucoma patients following a single-dose and constant therapy with coronary agent, Bay a 1040].
Topics: Adult; Capsules; Coronary Circulation; Drug Evaluation; Glaucoma; Humans; Intraocular Pressure; Meth | 1974 |