nifedipine has been researched along with Intermittent Claudication in 8 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Intermittent Claudication: A symptom complex characterized by pain and weakness in SKELETAL MUSCLE group associated with exercise, such as leg pain and weakness brought on by walking. Such muscle limpness disappears after a brief rest and is often relates to arterial STENOSIS; muscle ISCHEMIA; and accumulation of LACTATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a double-blind, crossover trial 12 patients with hypertension and peripheral arterial disease were randomized to three months' treatment with captopril 25-50 mg twice daily or nifedipine SR 20-40 mg twice daily." | 9.07 | Double-blind comparison of captopril with nifedipine in hypertension complicated by intermittent claudication. ( Breckenridge, A; Linge, K; McLoughlin, GA; Roberts, DH; Tsao, Y, 1992) |
| "To determine the effects of the beta 1 selective adrenoceptor blocker atenolol, the dihydropyridine calcium antagonist nifedipine, and the combination of atenolol plus nifedipine on objective and subjective measures of walking performance and foot temperature in patients with intermittent claudication." | 9.07 | beta blockade and intermittent claudication: placebo controlled trial of atenolol and nifedipine and their combination. ( Morris-Jones, W; Parnell, L; Ramsay, LE; Solomon, SA; Yeo, WW, 1991) |
| "The systemic treatment effects of OP-1206 alpha-CD (17S-20-dimethyl-trans-delta 2-PGE1 alpha-cyclodextrin clathrate), a prostaglandin E1 (PGE1) analogue, on walking dysfunction, spinal cord blood flow (SCBF) and skin blood flow (SKBF) were assessed in the rat neuropathic intermittent claudication (IC) model in comparison with nifedipine (dimethyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate), ticlopidine (5-[(2-chlorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-C]pyridine hydrochloride) and cilostazol (6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)-butoxy]-3,4-dihydro-2(1H)-quinolinone)." | 7.72 | Effects of OP-1206 alpha-CD on walking dysfunction in the rat neuropathic intermittent claudication model: comparison with nifedipine, ticlopidine and cilostazol. ( Akimaru, S; Ito, H; Katsube, N; Maegawa, H; Marsala, M; Nakai, K; Takenobu, Y; Takimizu, H, 2003) |
| "Pentoxifylline was significantly more effective (P < 0." | 6.67 | Comparative evaluation of pentoxifylline, buflomedil, and nifedipine in the treatment of intermittent claudication of the lower limbs. ( Calleja, F; Casares, J; Chacón-Quevedo, A; Concha, M; Eguaras, MG; Garcia, MA; Muñoz, I; Roman, M, 1994) |
| "In a double-blind, crossover trial 12 patients with hypertension and peripheral arterial disease were randomized to three months' treatment with captopril 25-50 mg twice daily or nifedipine SR 20-40 mg twice daily." | 5.07 | Double-blind comparison of captopril with nifedipine in hypertension complicated by intermittent claudication. ( Breckenridge, A; Linge, K; McLoughlin, GA; Roberts, DH; Tsao, Y, 1992) |
| "The calcium antagonist nifedipine has been studied in a group of patients with intermittent claudication." | 5.06 | Nifedipine in patients with peripheral vascular disease. ( Davies, WT; Lewis, P; Morgan, RH; Psaila, JV; Woodcock, JP, 1989) |
| "The systemic treatment effects of OP-1206 alpha-CD (17S-20-dimethyl-trans-delta 2-PGE1 alpha-cyclodextrin clathrate), a prostaglandin E1 (PGE1) analogue, on walking dysfunction, spinal cord blood flow (SCBF) and skin blood flow (SKBF) were assessed in the rat neuropathic intermittent claudication (IC) model in comparison with nifedipine (dimethyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate), ticlopidine (5-[(2-chlorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-C]pyridine hydrochloride) and cilostazol (6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)-butoxy]-3,4-dihydro-2(1H)-quinolinone)." | 3.72 | Effects of OP-1206 alpha-CD on walking dysfunction in the rat neuropathic intermittent claudication model: comparison with nifedipine, ticlopidine and cilostazol. ( Akimaru, S; Ito, H; Katsube, N; Maegawa, H; Marsala, M; Nakai, K; Takenobu, Y; Takimizu, H, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakai, K | 1 |
| Takenobu, Y | 1 |
| Takimizu, H | 1 |
| Akimaru, S | 1 |
| Maegawa, H | 1 |
| Ito, H | 1 |
| Marsala, M | 1 |
| Katsube, N | 1 |
| Gascón Ramón, G | 1 |
| Chacón-Quevedo, A | 1 |
| Eguaras, MG | 1 |
| Calleja, F | 1 |
| Garcia, MA | 1 |
| Roman, M | 1 |
| Casares, J | 1 |
| Muñoz, I | 1 |
| Concha, M | 1 |
| Pola, P | 1 |
| Savi, L | 1 |
| Dal Lago, A | 1 |
| Zucchiatti, V | 1 |
| Roberts, DH | 1 |
| Tsao, Y | 1 |
| Linge, K | 1 |
| McLoughlin, GA | 1 |
| Breckenridge, A | 1 |
| Solomon, SA | 1 |
| Ramsay, LE | 1 |
| Yeo, WW | 1 |
| Parnell, L | 1 |
| Morris-Jones, W | 1 |
| Lewis, P | 2 |
| Psaila, JV | 2 |
| Davies, WT | 2 |
| Morgan, RH | 2 |
| Woodcock, JP | 2 |
4 trials available for nifedipine and Intermittent Claudication
| Article | Year |
|---|---|
Comparative evaluation of pentoxifylline, buflomedil, and nifedipine in the treatment of intermittent claudication of the lower limbs.
Topics: Adult; Aged; Blood Pressure; Double-Blind Method; Exercise Test; Humans; Intermittent Claudication; | 1994 |
Double-blind comparison of captopril with nifedipine in hypertension complicated by intermittent claudication.
Topics: Blood Pressure; Captopril; Double-Blind Method; Exercise Test; Female; Humans; Hypertension; Intermi | 1992 |
beta blockade and intermittent claudication: placebo controlled trial of atenolol and nifedipine and their combination.
Topics: Adult; Aged; Atenolol; Blood Pressure; Delayed-Action Preparations; Double-Blind Method; Drug Therap | 1991 |
Nifedipine in patients with peripheral vascular disease.
Topics: Administration, Sublingual; Adult; Aged; Aged, 80 and over; Clinical Trials as Topic; Double-Blind M | 1989 |
4 other studies available for nifedipine and Intermittent Claudication
| Article | Year |
|---|---|
Effects of OP-1206 alpha-CD on walking dysfunction in the rat neuropathic intermittent claudication model: comparison with nifedipine, ticlopidine and cilostazol.
Topics: Alprostadil; Animals; Body Weight; Cilostazol; Disease Models, Animal; Exercise Test; Intermittent C | 2003 |
[Nifedipine in intermittent claudication].
Topics: Aged; Humans; Intermittent Claudication; Leg; Male; Nifedipine | 1984 |
[Vasodilation caused by inhibition of calcium ions as a factor of increasing oxygen transport in peripheral vascular diseases].
Topics: Adult; Aged; Arterial Occlusive Diseases; Arteriosclerosis Obliterans; Calcium; Coronary Disease; Hu | 1977 |
The effects of nifedipine on blood flow in peripheral vascular disease of the lower limbs.
Topics: Administration, Sublingual; Aged; Blood Flow Velocity; Blood Pressure; Female; Femoral Artery; Human | 1987 |