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nifedipine and Insulin Resistance

nifedipine has been researched along with Insulin Resistance in 14 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to evaluate the effects of barnidipine+losartan compared with telmisartan+hydrochlorothiazide on several parameters of insulin sensitivity in patients with hypertension and type 2 diabetes mellitus."9.20Comparison of the effects of barnidipine+losartan compared with telmisartan+hydrochlorothiazide on several parameters of insulin sensitivity in patients with hypertension and type 2 diabetes mellitus. ( D'Angelo, A; Dario Ragonesi, P; Derosa, G; Franzetti, I; Maffioli, P; Querci, F, 2015)
"We evaluated insulin sensitivity in two groups of essential hypertensive subjects before and after treatment with either long-acting nifedipine (nifedipine-CR, Adalat CR tablets; Bayer Yakuhin, Osaka, Japan) (n = 10) or metoprolol (n = 9)."9.10Improvement of insulin sensitivity by a long-acting nifedipine preparation (nifedipine-CR) in patients with essential hypertension. ( Harano, Y; Kodama, K; Koyama, Y; Suzuki, M, 2002)
"The aim of this study was to evaluate the effect of trandolapril, an angiotensin converting enzyme inhibitor, on blood pressure, forearm blood flow and insulin sensitivity in comparison with nifedipine gastrointestinal therapeutic system."9.09Controlled study of the effect of angiotensin converting enzyme inhibition versus calcium-entry blockade on insulin sensitivity in overweight hypertensive patients: Trandolapril Italian Study (TRIS). ( Capaldo, B; Carretta, R; Fabris, F; Ferrara, LA; Galletti, F; Glorioso, N; Mancini, M; Semplicini, A; Strazzullo, P, 1999)
"To investigate the effect of amlodipine, nifedipine and perindopril on insulin sensitivity(IS) and blood lipid of patients with essential hypertension(EH)."9.08[The effect of amlodipine, nifedipine and perindopril on insulin sensitivity and blood lipid of patients with essential hypertension]. ( Chen, D; Lin, J; Wu, K, 1998)
"To assess the effects of a vasodilatory beta-adrenoceptor blocker, nipradilol, and a long-acting Ca channel blocker, barnidipine, on insulin sensitivity."7.70Effect of the vasodilatory beta-blocker, nipradilol, and Ca-antagonist, barnidipine, on insulin sensitivity in patients with essential hypertension. ( Awata, T; Inaba, M; Katayama, S; Kosegawa, I; Morita, T, 1998)
"The improvement in postprandial lipidemia by nifedipine may add to its anti-atherogenic effects in hypertensive patients."6.82Nifedipine Treatment for Hypertension is Associated with Enhanced Lipolytic Activity and Accelerated Clearance of Postprandial Lipemia. ( Charach, G; Grosskopf, I; Harats, D; Kamari, Y; Shaish, A, 2016)
"Nifedipine-treated obese males showed a mild but significant decrease in weight gain that was due to a decrease in fat deposition in both subcutaneous and abdominal depots and systolic blood pressure was significantly reduced after one month of treatment."5.29Treatment of obese female and male SHHF/Mcc-fa(cp) rats with antihypertensive drugs, nifedipine and enalapril: effects on body weight, fat distribution, insulin resistance and systolic pressure. ( Chu, YY; Hoepf, TM; McCune, SA; Radin, MJ, 1993)
"The aim of this study was to evaluate the effects of barnidipine+losartan compared with telmisartan+hydrochlorothiazide on several parameters of insulin sensitivity in patients with hypertension and type 2 diabetes mellitus."5.20Comparison of the effects of barnidipine+losartan compared with telmisartan+hydrochlorothiazide on several parameters of insulin sensitivity in patients with hypertension and type 2 diabetes mellitus. ( D'Angelo, A; Dario Ragonesi, P; Derosa, G; Franzetti, I; Maffioli, P; Querci, F, 2015)
"We evaluated insulin sensitivity in two groups of essential hypertensive subjects before and after treatment with either long-acting nifedipine (nifedipine-CR, Adalat CR tablets; Bayer Yakuhin, Osaka, Japan) (n = 10) or metoprolol (n = 9)."5.10Improvement of insulin sensitivity by a long-acting nifedipine preparation (nifedipine-CR) in patients with essential hypertension. ( Harano, Y; Kodama, K; Koyama, Y; Suzuki, M, 2002)
"The aim of this study was to evaluate the effect of trandolapril, an angiotensin converting enzyme inhibitor, on blood pressure, forearm blood flow and insulin sensitivity in comparison with nifedipine gastrointestinal therapeutic system."5.09Controlled study of the effect of angiotensin converting enzyme inhibition versus calcium-entry blockade on insulin sensitivity in overweight hypertensive patients: Trandolapril Italian Study (TRIS). ( Capaldo, B; Carretta, R; Fabris, F; Ferrara, LA; Galletti, F; Glorioso, N; Mancini, M; Semplicini, A; Strazzullo, P, 1999)
"To investigate the effect of amlodipine, nifedipine and perindopril on insulin sensitivity(IS) and blood lipid of patients with essential hypertension(EH)."5.08[The effect of amlodipine, nifedipine and perindopril on insulin sensitivity and blood lipid of patients with essential hypertension]. ( Chen, D; Lin, J; Wu, K, 1998)
"These results suggest that nifedipine can enhance insulin sensitivity and reduce white adipose tissue, possibly related to stimulation of adipocyte differentiation."3.77Nifedipine, a calcium-channel blocker, attenuated glucose intolerance and white adipose tissue dysfunction in type 2 diabetic KK-A(y) mice. ( Horiuchi, M; Inaba, S; Iwai, M; Kanno, H; Nakaoka, H; Senba, I; Sone, H, 2011)
"To assess the effects of a vasodilatory beta-adrenoceptor blocker, nipradilol, and a long-acting Ca channel blocker, barnidipine, on insulin sensitivity."3.70Effect of the vasodilatory beta-blocker, nipradilol, and Ca-antagonist, barnidipine, on insulin sensitivity in patients with essential hypertension. ( Awata, T; Inaba, M; Katayama, S; Kosegawa, I; Morita, T, 1998)
"The improvement in postprandial lipidemia by nifedipine may add to its anti-atherogenic effects in hypertensive patients."2.82Nifedipine Treatment for Hypertension is Associated with Enhanced Lipolytic Activity and Accelerated Clearance of Postprandial Lipemia. ( Charach, G; Grosskopf, I; Harats, D; Kamari, Y; Shaish, A, 2016)
"Nifedipine-treated obese males showed a mild but significant decrease in weight gain that was due to a decrease in fat deposition in both subcutaneous and abdominal depots and systolic blood pressure was significantly reduced after one month of treatment."1.29Treatment of obese female and male SHHF/Mcc-fa(cp) rats with antihypertensive drugs, nifedipine and enalapril: effects on body weight, fat distribution, insulin resistance and systolic pressure. ( Chu, YY; Hoepf, TM; McCune, SA; Radin, MJ, 1993)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (35.71)18.2507
2000's4 (28.57)29.6817
2010's5 (35.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lee, S1
Han, D1
Kang, HG1
Jeong, SJ1
Jo, JE1
Shin, J1
Kim, DK1
Park, HW1
Derosa, G1
Querci, F1
Franzetti, I1
Dario Ragonesi, P1
D'Angelo, A1
Maffioli, P1
Cicero, AF1
Tocci, G1
Grosskopf, I1
Shaish, A1
Charach, G1
Harats, D1
Kamari, Y1
Iwai, M1
Kanno, H1
Inaba, S1
Senba, I1
Sone, H1
Nakaoka, H1
Horiuchi, M1
Koyama, Y1
Kodama, K1
Suzuki, M1
Harano, Y1
Yoshida, D1
Higashiura, K1
Shimamoto, K1
Radin, MJ1
Chu, YY1
Hoepf, TM1
McCune, SA1
Francini, F1
Gagliardino, JJ1
Borelli, MI1
Kosegawa, I1
Inaba, M1
Morita, T1
Awata, T1
Katayama, S1
Galletti, F1
Strazzullo, P1
Capaldo, B1
Carretta, R1
Fabris, F1
Ferrara, LA1
Glorioso, N1
Semplicini, A1
Mancini, M1
Lin, J1
Chen, D1
Wu, K1
Dimo, T1
Rakotonirina, A1
Tan, PV1
Dongo, E1
Dongmo, AB1
Kamtchouing, P1
Azay, J1
Abegaz, BM1
Cros, G1
Ngadjui, TB1
Eckel, J1
Asskamp, B1
Reinauer, H1

Reviews

1 review available for nifedipine and Insulin Resistance

ArticleYear
[Treatment of hypertensive patients with impaired glucose tolerance (IGT)].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 2

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive

2005

Trials

5 trials available for nifedipine and Insulin Resistance

ArticleYear
Comparison of the effects of barnidipine+losartan compared with telmisartan+hydrochlorothiazide on several parameters of insulin sensitivity in patients with hypertension and type 2 diabetes mellitus.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2015, Volume: 38, Issue:10

    Topics: Adipokines; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles;

2015
Nifedipine Treatment for Hypertension is Associated with Enhanced Lipolytic Activity and Accelerated Clearance of Postprandial Lipemia.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2016, Volume: 48, Issue:4

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Female; Humans; Hyperlipidemias; Hypertension;

2016
Improvement of insulin sensitivity by a long-acting nifedipine preparation (nifedipine-CR) in patients with essential hypertension.
    American journal of hypertension, 2002, Volume: 15, Issue:11

    Topics: Adrenergic beta-Antagonists; Aged; Area Under Curve; Blood Glucose; Calcium Channel Blockers; Delaye

2002
Controlled study of the effect of angiotensin converting enzyme inhibition versus calcium-entry blockade on insulin sensitivity in overweight hypertensive patients: Trandolapril Italian Study (TRIS).
    Journal of hypertension, 1999, Volume: 17, Issue:3

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Flow Velocity; Blood Pressure; Calcium;

1999
[The effect of amlodipine, nifedipine and perindopril on insulin sensitivity and blood lipid of patients with essential hypertension].
    Zhonghua yi xue za zhi, 1998, Volume: 78, Issue:3

    Topics: Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Female; Humans; Hypertension; Insulin

1998

Other Studies

8 other studies available for nifedipine and Insulin Resistance

ArticleYear
Intravenous sustained-release nifedipine ameliorates nonalcoholic fatty liver disease by restoring autophagic clearance.
    Biomaterials, 2019, Volume: 197

    Topics: Administration, Intravenous; Animals; Autophagy; Calcium Channel Blockers; Delayed-Action Preparatio

2019
Metabolic approaches to antihypertensive treatment in diabetic patients.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2015, Volume: 38, Issue:12

    Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Calcium

2015
Nifedipine, a calcium-channel blocker, attenuated glucose intolerance and white adipose tissue dysfunction in type 2 diabetic KK-A(y) mice.
    American journal of hypertension, 2011, Volume: 24, Issue:2

    Topics: Adipocytes; Adipogenesis; Adiponectin; Adipose Tissue, White; Animals; Blood Glucose; Calcium Channe

2011
Treatment of obese female and male SHHF/Mcc-fa(cp) rats with antihypertensive drugs, nifedipine and enalapril: effects on body weight, fat distribution, insulin resistance and systolic pressure.
    Obesity research, 1993, Volume: 1, Issue:6

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Composition; Body Constitution; Body Weight;

1993
Decreased islet sensitivity to insulin in hamsters with dietary-induced insulin resistance.
    Life sciences, 2008, Apr-09, Volume: 82, Issue:15-16

    Topics: Androstadienes; Animals; Body Water; Body Weight; Calcium Channel Blockers; Carbon Dioxide; Cricetin

2008
Effect of the vasodilatory beta-blocker, nipradilol, and Ca-antagonist, barnidipine, on insulin sensitivity in patients with essential hypertension.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 1998, Volume: 20, Issue:7

    Topics: Adrenergic beta-Antagonists; Blood Pressure; Calcium Channel Blockers; Female; Glucose Clamp Techniq

1998
Antihypertensive effects of Dorstenia psilurus extract in fructose-fed hyperinsulinemic, hypertensive rats.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2001, Volume: 8, Issue:2

    Topics: Africa; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Cholesterol; Creatinine; Di

2001
Induction of insulin resistance in primary cultured adult cardiac myocytes.
    Endocrinology, 1991, Volume: 129, Issue:1

    Topics: Animals; Biological Transport; Bucladesine; Cells, Cultured; Cyclic AMP; Cycloheximide; Cytochalasin

1991