nifedipine has been researched along with Injury, Myocardial Reperfusion in 45 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The comparative effects of the calcium-antagonists gallopamil and nifedipine on ischemia-induced and reperfusion-induced ventricular arrhythmias, particularly ventricular fibrillation (VF), were assessed in a total of 40 mongrel dogs in two experimental preparations." | 7.67 | Calcium antagonists and acute myocardial ischemia: comparative effects of gallopamil and nifedipine on ischemia-induced and reperfusion-induced ventricular arrhythmias, epicardial conduction times, and ventricular fibrillation thresholds. ( Bender, F; Gülker, H; Haverkamp, W; Hindricks, G, 1987) |
| "The effects of pretreatment with cariporide on myocardial infarction and ventricular arrhythmias in a rat model of ischemia/reperfusion were compared with those of nicorandil, propranolol, and nifedipine." | 3.72 | Effects of cariporide (HOE642) on myocardial infarct size and ventricular arrhythmias in a rat ischemia/reperfusion model: comparison with other drugs. ( Beguier, B; Wajima, T; Yaguchi, M, 2004) |
| "The effects of SMP-300, an orally active, potent, and selective Na+/H+ exchange inhibitor, were evaluated and compared with those of nifedipine, propranolol, and nicorandil on three experimental angina models and on myocardial infarction in rats." | 3.71 | Effect of an orally active Na+/H+ exchange inhibitor, SMP-300, on experimental angina and myocardial infarction models in rats. ( Matsui, K; Ohashi, N; Sasabe, M; Yamamoto, S, 2002) |
| "Myocardial infarction induced by coronary occlusion (O model) and reperfusion (R model) and the effects of nitroglycerin (Nit), propranolol (Pro), lidocaine (Lid), nifedipine (Nif), and saline were studied in rats by image analysis and weighing methods." | 3.68 | [Image analysis of effects of 4 drugs on coronary occlusion and myocardial reperfusion injury]. ( Han, L; Tang, ZM, 1993) |
| "The aim of the present study was to define the protective effects of verapamil and nifedipine on mechanical performance and energy and substrate metabolism of the postischemically reperfused myocardium in a chronic pressure overload cardiac hypertrophy model." | 3.68 | Protective effects of calcium antagonists on energy and substrate metabolism during ischemia and reperfusion in hypertensive myocardial hypertrophy. ( Buser, PT; Higgins, CB; Wagner, S; Wikman-Coffelt, J; Wu, S, 1991) |
| "The effects of three calcium antagonists (diltiazem, verapamil, and nifedipine) on reperfusion-induced arrhythmias were compared in a conscious rat preparation with coronary artery occlusion and implanted electrocardiogram limb electrodes." | 3.67 | Reperfusion-induced arrhythmias in the conscious rat: a comparative study with three calcium antagonists. ( Braimbridge, MV; Hearse, DJ; Kinoshita, K; Manning, AS; Mitani, A, 1989) |
| "The comparative effects of the calcium-antagonists gallopamil and nifedipine on ischemia-induced and reperfusion-induced ventricular arrhythmias, particularly ventricular fibrillation (VF), were assessed in a total of 40 mongrel dogs in two experimental preparations." | 3.67 | Calcium antagonists and acute myocardial ischemia: comparative effects of gallopamil and nifedipine on ischemia-induced and reperfusion-induced ventricular arrhythmias, epicardial conduction times, and ventricular fibrillation thresholds. ( Bender, F; Gülker, H; Haverkamp, W; Hindricks, G, 1987) |
| "Amlodipine is an intrinsically long-acting, vasoselective calcium antagonist structurally related to nifedipine, but with unique binding and pharmacologic properties that distinguish it from other agents of this class." | 2.39 | Unique pharmacologic properties of amlodipine. ( Burges, R; Moisey, D, 1994) |
| "With verapamil there is a small tendency for a reduction in reinfarction, with nifedipine a clear worsening, and with diltiazem a reduction almost reaching statistical significance." | 2.38 | Protective effects of calcium antagonists against ischaemia and reperfusion damage. ( Ferrari, R; Visioli, O, 1991) |
| "Diltiazem was the less effective drug on both left ventricular hemodynamics and coronary circulation." | 1.30 | Calcium-channel blockers preserve coronary endothelial reactivity after ischemia-reperfusion. ( Buluran, J; Cartier, R; Dagenais, F; Hollmann, C, 1997) |
| "Halothane has been shown to be a powerful myocardial protectant during normothermic cardioplegic arrest and subsequent reperfusion." | 1.30 | Postcardioplegic myocardial recovery: effects of halothane, nifedipine, HOE 694, and quinacrine. ( Genade, S; Lochner, A; Theron, S; Trollip, G; Tromp, E, 1998) |
| "Nifedipine (0." | 1.29 | [Clinical observation of the effect of pretreatment with nifedipine in preventing oxygen free radicals in the cardiopulmonary release bypass operation]. ( Huang, X; Shi, Y; Tian, Z; Wu, X; Xiao, X; Yin, Q; Yuan, H, 1993) |
| "4." | 1.28 | Impaired endothelium-dependent relaxation of dog coronary arteries after myocardial ischaemia and reperfusion: prevention by amlodipine, propranolol and allopurinol. ( Dalipram, RA; Dusting, GJ; Sobey, CG; Woodman, OL, 1992) |
| "Amlodipine is a long-acting dihydropyridine calcium antagonist with vascular selectivity." | 1.28 | Vascular and myocardial effects of amlodipine: an overview. ( Gu, XH; Nayler, WG, 1991) |
| "Amlodipine is a dihydropyridine derivative belonging to the group of pharmacologic calcium entry blocking agents and is characterized as having a slow onset and relatively long duration of action with minimal effects on cardiac electrophysiology and myocardial contractility." | 1.28 | Cardioprotective effects of amlodipine in the ischemic-reperfused heart. ( Hoff, PT; Lucchesi, BR; Tamura, Y, 1989) |
| "Amlodipine is a long-acting dihydropyridine-based Ca2+ channel blocker, developed for use on a once-daily basis." | 1.28 | Amlodipine pretreatment and the ischemic heart. ( Nayler, WG, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (31.11) | 18.7374 |
| 1990's | 23 (51.11) | 18.2507 |
| 2000's | 7 (15.56) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (2.22) | 2.80 |
| Authors | Studies |
|---|---|
| Lauro, FV | 1 |
| Marcela, RN | 1 |
| Maria, LR | 1 |
| Magdalena, AR | 1 |
| Virginia, MM | 1 |
| Francisco, DC | 1 |
| Alejandra, GE | 1 |
| Tomas, LG | 1 |
| Montserrat, MG | 1 |
| Wajima, T | 1 |
| Beguier, B | 1 |
| Yaguchi, M | 1 |
| Camara, AK | 1 |
| Chen, Q | 1 |
| Rhodes, SS | 1 |
| Riess, ML | 1 |
| Stowe, DF | 1 |
| Seth, SD | 1 |
| Maulik, SK | 1 |
| Manchanda, SC | 1 |
| Maulik, MG | 1 |
| Reddy, KS | 1 |
| Gupta, YK | 1 |
| Han, L | 1 |
| Tang, ZM | 1 |
| Burges, R | 1 |
| Moisey, D | 1 |
| Jiang, H | 1 |
| Rao, MR | 3 |
| Xiao, X | 1 |
| Tian, Z | 1 |
| Wu, X | 1 |
| Yin, Q | 1 |
| Huang, X | 1 |
| Yuan, H | 1 |
| Shi, Y | 1 |
| Liu, X | 1 |
| Engelman, RM | 1 |
| Wei, Z | 1 |
| Bagchi, D | 1 |
| Rousou, JA | 1 |
| Nath, D | 1 |
| Das, DK | 1 |
| Knothe, C | 1 |
| Boldt, J | 1 |
| Dehne, M | 1 |
| Zickmann, B | 1 |
| Porsch, S | 1 |
| Dapper, F | 1 |
| Hempelmann, G | 1 |
| Dagenais, F | 1 |
| Cartier, R | 1 |
| Hollmann, C | 1 |
| Buluran, J | 1 |
| Smart, SC | 2 |
| Sagar, KB | 2 |
| el Schultz, J | 1 |
| Warltier, DC | 3 |
| Jones, LR | 1 |
| Lochner, A | 1 |
| Genade, S | 1 |
| Tromp, E | 1 |
| Theron, S | 1 |
| Trollip, G | 1 |
| Becker, BF | 1 |
| Möbert, J | 1 |
| Ordoñez Fernández, A | 1 |
| Hernandez Fernandez, A | 1 |
| Borrego Dominguez, JM | 1 |
| Gutierrez Carretero, E | 1 |
| Muñoz García, J | 1 |
| Prieto Rodriguez, MF | 1 |
| Viloria Peñas, MM | 1 |
| Hayashi, Y | 1 |
| Tajima, K | 1 |
| Kirimoto, T | 1 |
| Miyake, H | 1 |
| Matsuura, N | 1 |
| Gen, W | 1 |
| Tani, M | 1 |
| Takeshita, J | 1 |
| Ebihara, Y | 1 |
| Tamaki, K | 1 |
| Yamamoto, S | 1 |
| Matsui, K | 1 |
| Sasabe, M | 1 |
| Ohashi, N | 1 |
| Saeki, K | 1 |
| Obi, I | 1 |
| Ogiku, N | 1 |
| Shigekawa, M | 1 |
| Imagawa, T | 1 |
| Matsumoto, T | 1 |
| Gross, GJ | 3 |
| Auchampach, JA | 1 |
| Maruyama, M | 1 |
| Pieper, GM | 3 |
| Sheiban, I | 1 |
| Tonni, S | 1 |
| Benussi, P | 1 |
| Marini, A | 1 |
| Montresor, G | 1 |
| Trevi, GP | 1 |
| Yang, JR | 1 |
| Li, QP | 1 |
| Sobey, CG | 1 |
| Dalipram, RA | 1 |
| Dusting, GJ | 1 |
| Woodman, OL | 1 |
| Ferrari, R | 1 |
| Visioli, O | 1 |
| Heijnis, JB | 1 |
| Mathy, MJ | 1 |
| van Zwieten, PA | 1 |
| Buser, PT | 1 |
| Wagner, S | 1 |
| Wu, S | 1 |
| Higgins, CB | 1 |
| Wikman-Coffelt, J | 1 |
| Nayler, WG | 3 |
| Gu, XH | 1 |
| Liu, JJ | 1 |
| Panagiotopoulos, S | 1 |
| Hoff, PT | 2 |
| Tamura, Y | 3 |
| Lucchesi, BR | 3 |
| Mrak, RE | 1 |
| Carry, MM | 1 |
| Murphy, ML | 2 |
| Peng, CF | 2 |
| Straub, KD | 2 |
| Klein, HH | 1 |
| Pich, S | 1 |
| Lindert, S | 1 |
| Nebendahl, K | 1 |
| Warneke, G | 1 |
| Kreuzer, H | 1 |
| Farber, NE | 2 |
| Zhang, HL | 1 |
| Fu, SX | 2 |
| Li, YS | 2 |
| Kinoshita, K | 1 |
| Mitani, A | 1 |
| Hearse, DJ | 1 |
| Braimbridge, MV | 1 |
| Manning, AS | 1 |
| Chen, NH | 1 |
| Przyklenk, K | 1 |
| Ghafari, GB | 1 |
| Eitzman, DT | 1 |
| Kloner, RA | 1 |
| Gülker, H | 1 |
| Haverkamp, W | 1 |
| Hindricks, G | 1 |
| Bender, F | 1 |
| Odom, H | 1 |
| Davis, JL | 1 |
| Li, YL | 1 |
| Dzumhur, S | 1 |
| Brown, AH | 1 |
3 reviews available for nifedipine and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Unique pharmacologic properties of amlodipine.
Topics: Amlodipine; Animals; Aorta; Calcium Channel Blockers; Delayed-Action Preparations; Dogs; Hypertensio | 1994 |
Protective effects of calcium antagonists against ischaemia and reperfusion damage.
Topics: Calcium; Calcium Channel Blockers; Coronary Disease; Diltiazem; Humans; Myocardial Reperfusion Injur | 1991 |
Cardioprotective effects of amlodipine on ischemia and reperfusion in two experimental models.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cats; Coronary Disease; Dogs; In Vitro Techniques; My | 1990 |
1 trial available for nifedipine and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Myocardial stunning following coronary angioplasty: protective effects of calcium-channel blockers.
Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Female; Hemodynamics; Humans; | 1992 |
41 other studies available for nifedipine and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Evaluation of Biological Activity of a Diazocine Derivative against Heart Failure Using an Ischemia-Reperfusion Injury Model.
Topics: Animals; Heart; Heart Failure; Infarction; Myocardial Reperfusion Injury; Nifedipine; Rats | 2022 |
Effects of cariporide (HOE642) on myocardial infarct size and ventricular arrhythmias in a rat ischemia/reperfusion model: comparison with other drugs.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Dose-Response Relationship, Drug; Electrocardiograp | 2004 |
Negative inotropic drugs alter indexes of cytosolic [Ca(2+)]-left ventricular pressure relationships after ischemia.
Topics: Animals; Benzopyrans; Calcium; Calcium Channel Blockers; Cardiotonic Agents; Cytosol; Diacetyl; Dihy | 2004 |
Recovery from reperfusion injury in intact canine heart by nifedipine.
Topics: Adenosine Triphosphate; Animals; Dogs; Female; Male; Myocardial Reperfusion Injury; Nifedipine; Phos | 1993 |
[Image analysis of effects of 4 drugs on coronary occlusion and myocardial reperfusion injury].
Topics: Animals; Female; Image Processing, Computer-Assisted; Male; Myocardial Infarction; Myocardial Reperf | 1993 |
[Protective effects of m-nifedipine and nifedipine in isolated ischemic-reperfused rat hearts].
Topics: Animals; Blood Pressure; Compliance; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Nifed | 1993 |
[Clinical observation of the effect of pretreatment with nifedipine in preventing oxygen free radicals in the cardiopulmonary release bypass operation].
Topics: Adolescent; Adult; Cardiopulmonary Bypass; Child; Child, Preschool; Female; Free Radicals; Heart Def | 1993 |
Attenuation of myocardial reperfusion injury by reducing intracellular calcium overloading with dihydropyridines.
Topics: Animals; Calcium; Coronary Circulation; Creatine Kinase; Dihydropyridines; Free Radical Scavengers; | 1993 |
Comparison of different prophylactic myocardium saving measures during heart surgery. Effects on perioperative troponin-T levels.
Topics: Aged; Biomarkers; Calcium Channel Blockers; Cardiopulmonary Bypass; Coronary Artery Bypass; Electroc | 1996 |
Calcium-channel blockers preserve coronary endothelial reactivity after ischemia-reperfusion.
Topics: Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Vessels; Diltiazem; Dose-Response | 1997 |
Injury to the Ca2+ ATPase of the sarcoplasmic reticulum in anesthetized dogs contributes to myocardial reperfusion injury.
Topics: Animals; Antibodies, Monoclonal; Calcium; Calcium Channel Blockers; Calcium-Binding Proteins; Calciu | 1997 |
Differential roles of myocardial Ca2+ channels and Na+/Ca2+ exchange in myocardial reperfusion injury in open chest dogs: relative roles during ischemia and reperfusion.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1997 |
Postcardioplegic myocardial recovery: effects of halothane, nifedipine, HOE 694, and quinacrine.
Topics: Analysis of Variance; Anesthetics, Inhalation; Animals; Calcium Channel Blockers; Dose-Response Rela | 1998 |
Low-dose calcium antagonists reduce energy demand and cellular damage of isolated hearts during both ischemia and reperfusion.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Coronary Circulation; Diltiazem; Dose-Response Relati | 1999 |
Coronary vasomotor disorders during hypoxia-reoxygenation: do calcium channel blockers play a protective role?
Topics: Adenosine Diphosphate; Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Vasospasm; | 2000 |
Cardioprotective effects of MET-88, a gamma-butyrobetaine hydroxylase inhibitor, on cardiac dysfunction induced by ischemia/reperfusion in isolated rat hearts.
Topics: Animals; Carnitine; Enzyme Inhibitors; gamma-Butyrobetaine Dioxygenase; Heart Function Tests; Hemody | 2000 |
Mechanisms of Ca2+ overload induced by extracellular H2O2 in quiescent isolated rat cardiomyocytes.
Topics: Alkaloids; Animals; Benzophenanthridines; Caffeine; Calcium; Calcium Channel Blockers; Catalase; Dos | 2001 |
Effect of an orally active Na+/H+ exchange inhibitor, SMP-300, on experimental angina and myocardial infarction models in rats.
Topics: Administration, Oral; Angina Pectoris; Animals; Azocines; Coronary Disease; Electrocardiography; Iso | 2002 |
Cardioprotective effects of 9-hydroxyellipticine on ischemia and reperfusion in isolated rat heart.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Binding, Competitive; Calcium; CHO Cells; Cri | 2002 |
Cardioprotective effects of nicorandil.
Topics: Animals; Benzopyrans; Coronary Circulation; Dihydropyridines; Dogs; Female; Heart; In Vitro Techniqu | 1992 |
[Protective effects of praeruptorin C and nifedipine on ischemia-reperfused injury in working rat hearts].
Topics: Animals; Calcium; Calcium Channel Blockers; Coumarins; Creatine Kinase; Female; Heart Rate; Hemodyna | 1992 |
Impaired endothelium-dependent relaxation of dog coronary arteries after myocardial ischaemia and reperfusion: prevention by amlodipine, propranolol and allopurinol.
Topics: Acetylcholine; Allopurinol; Amlodipine; Animals; Calcium Channel Blockers; Coronary Disease; Coronar | 1992 |
Effects of nifedipine on global myocardial ischemic injury in hearts from diabetic and age-matched control rats.
Topics: Animals; Blood Pressure; Calcium; Coronary Circulation; Coronary Disease; Diabetes Mellitus, Experim | 1991 |
Protective effects of calcium antagonists on energy and substrate metabolism during ischemia and reperfusion in hypertensive myocardial hypertrophy.
Topics: Adenosine Triphosphate; Animals; Calcium Channel Blockers; Cardiomegaly; Energy Metabolism; Hyperten | 1991 |
Vascular and myocardial effects of amlodipine: an overview.
Topics: Amlodipine; Animals; Arteriosclerosis; Binding Sites; Calcium Channel Blockers; Cardiomegaly; Cerebr | 1991 |
Nifedipine and experimental cardioprotection.
Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Binding Sites; Calcium; Cholesterol; Coronary Disease; E | 1990 |
Reperfusion injury in ischemic myocardium: effects of nifedipine and verapamil.
Topics: Animals; Blood Pressure; Calcium; Cell Nucleus; Glycogen; Microscopy, Electron; Mitochondria, Heart; | 1990 |
Treatment of reperfusion injury with intracoronary calcium channel antagonists and reduced coronary free calcium concentration in regionally ischemic, reperfused porcine hearts.
Topics: Animals; Calcium; Calcium Channel Blockers; Diltiazem; Egtazic Acid; Female; Infusions, Intra-Arteri | 1989 |
Cardioprotective effects of amlodipine in the ischemic-reperfused heart.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cats; Dogs; Heart; In Vitro Techniques; Myocardial Co | 1989 |
Cardioprotective effects of amlodipine in the ischemic-reperfused heart.
Topics: Amlodipine; Animals; Blood Pressure; Calcium; Calcium Channel Blockers; Cats; Compliance; Coronary C | 1989 |
Amlodipine pretreatment and the ischemic heart.
Topics: Acidosis; Adenosine Triphosphate; Amlodipine; Animals; Calcium; Calcium Channel Blockers; Coronary D | 1989 |
Effects of amlodipine on myocardial ischemia-reperfusion injury in dogs.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Coronary Circulation; Dogs; Energy Metabolism; Female | 1989 |
Effect of amlodipine on myocardial functional and metabolic recovery following coronary occlusion and reperfusion in dogs.
Topics: Adenine Nucleotides; Amlodipine; Animals; Calcium Channel Blockers; Coronary Disease; Coronary Vesse | 1989 |
[Protective effects of m-nisoldipine and nisoldipine on myocardial damage in working rabbit hearts after ischemia-reperfusion].
Topics: Animals; Calcium Channel Blockers; Creatine Kinase; Female; In Vitro Techniques; Isomerism; Male; My | 1989 |
Reperfusion-induced arrhythmias in the conscious rat: a comparative study with three calcium antagonists.
Topics: Animals; Arrhythmias, Cardiac; Consciousness; Coronary Disease; Diltiazem; Electrocardiography; Hear | 1989 |
[Protective effects of m-nifedipine and nifedipine on ischemic-reperfused injury in working guinea pig hearts].
Topics: Animals; Creatine Kinase; Female; Guinea Pigs; Hemodynamics; Male; Myocardial Reperfusion Injury; Ni | 1989 |
Nifedipine administered after reperfusion ablates systolic contractile dysfunction of postischemic "stunned" myocardium.
Topics: Animals; Coronary Circulation; Coronary Vessels; Dogs; Female; Heart; Hemodynamics; Injections; Inje | 1989 |
Calcium antagonists and acute myocardial ischemia: comparative effects of gallopamil and nifedipine on ischemia-induced and reperfusion-induced ventricular arrhythmias, epicardial conduction times, and ventricular fibrillation thresholds.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Calcium Channel Blockers; Coronary Disease; Dogs; Fem | 1987 |
Evaluation of biochemical functions and ventricular performance in regional ischemic-reperfused myocardium by afterload reduction: differential effects of calcium blocking and non-calcium blocking vasodilators.
Topics: Adenosine Triphosphate; Animals; Calcium; Heart; Mitochondria, Heart; Myocardial Contraction; Myocar | 1988 |
[Prophylactic effects of m-nisoldipine and nisoldipine on reperfusion arrhythmia in hearts of rats].
Topics: Animals; Arrhythmias, Cardiac; Calcium; Fatty Acids, Nonesterified; Free Radicals; Isomerism; Male; | 1988 |
Reperfusion with nifedipine: improved functional recovery after cold cardioplegic arrest.
Topics: Animals; Cardioplegic Solutions; Cold Temperature; Coronary Circulation; Creatine Kinase; Dose-Respo | 1988 |