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nifedipine and Injury, Ischemia-Reperfusion

nifedipine has been researched along with Injury, Ischemia-Reperfusion in 31 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the neuroprotective effects of benidipine hydrochloride on the cerebral cortex tissues in rats exposed to cerebral ischemia-reperfusion (I/R) injury."8.02Effects of Benidipine Hydrochloride on Ischemia Reperfusion Injury of Rat Brain. ( Arslan, YK; Cakir, T; Suleyman, H; Sunar, M; Yazici, GN; Yucetas, SC, 2021)
" Therefore, this study was aimed to investigate the effects of mebudipine on myocardial arrhythmias and tissue injury induced by ischemia/reperfusion injury in isolated rat hearts."7.83The effects of mebudipine on myocardial arrhythmia induced by ischemia-reperfusion injury in isolated rat heart. ( Badalzadeh, R; Ghiasi, A; Ghiasi, R; Majidinia, M; Mohammadi, M; Yousefi, B, 2016)
"The aim of the study was to determine if pretreatment with misoprostol (a prostaglandin analogue) or nifedipine (a calcium antagonist), know protectants of the whole liver, would ameliorate the ischemia-reperfusion injury (IRI) of resected liver associated with vascular occlusion."7.69Hepatic ischemia-reperfusion injury modification during liver surgery in rats: pretreatment with nifedipine or misoprostol. ( Hardy, KJ; Shulkes, A; Tancheroen, S, 1995)
"The effects of verapamil and nifedipine on cellular mechanisms of arrhythmia were examined in isolated canine Purkinje fiber-papillary muscles."7.68Effects of verapamil and nifedipine on mechanisms of arrhythmia in an in vitro model of ischemia and reperfusion. ( Ferrier, GR; Mohabir, R, 1991)
"To evaluate the neuroprotective effects of benidipine hydrochloride on the cerebral cortex tissues in rats exposed to cerebral ischemia-reperfusion (I/R) injury."4.02Effects of Benidipine Hydrochloride on Ischemia Reperfusion Injury of Rat Brain. ( Arslan, YK; Cakir, T; Suleyman, H; Sunar, M; Yazici, GN; Yucetas, SC, 2021)
" Therefore, this study was aimed to investigate the effects of mebudipine on myocardial arrhythmias and tissue injury induced by ischemia/reperfusion injury in isolated rat hearts."3.83The effects of mebudipine on myocardial arrhythmia induced by ischemia-reperfusion injury in isolated rat heart. ( Badalzadeh, R; Ghiasi, A; Ghiasi, R; Majidinia, M; Mohammadi, M; Yousefi, B, 2016)
" This study investigated the effects of nifedipine, an L-type voltage-gated Ca(2+) channel blocker, on ischemic lesion volume after focal cerebral ischemia and reperfusion in rats."3.77Nifedipine treatment reduces brain damage after transient focal ischemia, possibly through its antioxidative effects. ( Honda, Y; Ide, T; Shiba, T; Tsutsui, H; Yamada, K; Yamato, M, 2011)
"The effects of three drugs including ketamine(KT), a noncompetitive antagonist of NMDA receptor (NR), nifedipine(ND), a voltage gated calcium channel (VGCC) antagonist and 6, 7dinitroquinoxaline -2, 3-dione(DNQX), a non-NMDA receptor antagonist on the contents of phospho-tyrosine proteins (p-tyr-pr) in the synaptosomal(P2), the crude membrane (P3), and the cytosolic (S3) fractions of hippocampus in forebrain ischemia of mongolian gerbils were studied."3.71[Effects of ischemia/reperfusion on the phosphotyrosine proteins contents in hippocampus]. ( Gui, ZH; Li, Y; Pei, L; Zhang, GY; Zhu, ZM, 2001)
"To determine whether topical application of flunarizine reduces intraocular pressure (IOP) and acts as a retinal neuroprotectant and to compare the effectiveness of flunarizine with betaxolol and nifedipine at reducing the influx of calcium and sodium."3.71Topical flunarizine reduces IOP and protects the retina against ischemia-excitotoxicity. ( Chidlow, G; Cupido, A; Melena, J; Osborne, NN; Wood, JP, 2002)
"The aim of the study was to determine if pretreatment with misoprostol (a prostaglandin analogue) or nifedipine (a calcium antagonist), know protectants of the whole liver, would ameliorate the ischemia-reperfusion injury (IRI) of resected liver associated with vascular occlusion."3.69Hepatic ischemia-reperfusion injury modification during liver surgery in rats: pretreatment with nifedipine or misoprostol. ( Hardy, KJ; Shulkes, A; Tancheroen, S, 1995)
"The effects of verapamil and nifedipine on cellular mechanisms of arrhythmia were examined in isolated canine Purkinje fiber-papillary muscles."3.68Effects of verapamil and nifedipine on mechanisms of arrhythmia in an in vitro model of ischemia and reperfusion. ( Ferrier, GR; Mohabir, R, 1991)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (35.48)18.2507
2000's13 (41.94)29.6817
2010's6 (19.35)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
Tenti, G1
Parada, E1
León, R1
Egea, J1
Martínez-Revelles, S1
Briones, AM1
Sridharan, V1
López, MG1
Ramos, MT1
Menéndez, JC1
Cakir, T1
Yucetas, SC1
Yazici, GN1
Sunar, M1
Arslan, YK1
Suleyman, H1
Santa-Helena, E1
Teixeira, S1
Castro, MR1
Cabrera, DDC1
D'Oca, CDRM1
D'Oca, MGM1
Votto, APS1
Nery, LEM1
Gonçalves, CAN1
Eraslan, E1
Tanyeli, A1
Polat, E2
Ghiasi, R1
Mohammadi, M1
Majidinia, M1
Yousefi, B1
Ghiasi, A1
Badalzadeh, R1
Cipolla, MJ1
Bullinger, LV1
Tavakoli-Far, B1
Rahbar-Roshandel, N1
Rahimi-Moghaddam, P1
Mahmoudian, M1
Pei, L4
Li, Y4
Zhang, GY4
Gui, ZH1
Zhu, ZM3
Yamato, M1
Shiba, T1
Ide, T1
Honda, Y1
Yamada, K1
Tsutsui, H1
Rinker, B1
Fink, BF1
Stoker, AR1
Milan, ME1
Nelson, PT1
Zhang, C2
Shen, W2
Zhang, G2
El-Abhar, HS1
Shaalan, M1
Barakat, M1
El-Denshary, ES1
Chidlow, G2
Schmidt, KG1
Wood, JP2
Melena, J2
Osborne, NN2
Bagate, K1
Meiring, JJ1
Gerlofs-Nijland, ME1
Cassee, FR1
Wiegand, H1
Osornio-Vargas, A1
Borm, PJ1
Toronyi, E2
Haverich, A2
Karck, M2
Matsuda, T1
Takuma, K1
Nishiguchi, E1
Hashimoto, H1
Azuma, J1
Baba, A1
al-Dohayan, AD1
al-Tuwaijri, AS1
Hardy, KJ1
Tancheroen, S1
Shulkes, A1
Bouskela, E1
Cyrino, FZ1
Conde, CM1
Garcia, AA1
Hamar, J1
Perner, F1
Szende, B1
Cui, ZC2
Yan, JZ1
Cupido, A1
Mohabir, R1
Ferrier, GR1
Pickford, MA1
Green, CJ1
Sarathchandra, P1
Fryer, PR1
Ferguson, CJ1
Hillis, AN1
Williams, JD1
Griffin, PJ1
Salaman, JR1
Griffiths, EJ1
Brunt, RV1

Reviews

1 review available for nifedipine and Injury, Ischemia-Reperfusion

ArticleYear
[Role of apoptosis in the kidney after reperfusion].
    Orvosi hetilap, 2008, Feb-17, Volume: 149, Issue:7

    Topics: Animals; Apoptosis; Bepridil; Calcium Channel Blockers; Disease Models, Animal; Fendiline; Humans; K

2008

Other Studies

30 other studies available for nifedipine and Injury, Ischemia-Reperfusion

ArticleYear
New 5-unsubstituted dihydropyridines with improved CaV1.3 selectivity as potential neuroprotective agents against ischemic injury.
    Journal of medicinal chemistry, 2014, May-22, Volume: 57, Issue:10

    Topics: Animals; Brain Ischemia; Calcium; Calcium Channels, L-Type; Calcium Signaling; Cell Line, Tumor; Dih

2014
Effects of Benidipine Hydrochloride on Ischemia Reperfusion Injury of Rat Brain.
    Turkish neurosurgery, 2021, Volume: 31, Issue:3

    Topics: Animals; Brain; Brain Ischemia; Male; Neuroprotective Agents; Nifedipine; Random Allocation; Rats; R

2021
Protective role of the novel hybrid 3,5-dipalmitoyl-nifedipine in a cardiomyoblast culture subjected to simulated ischemia/reperfusion.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 92

    Topics: Animals; Calcium Channel Blockers; Cardiotonic Agents; Cell Survival; Cells, Cultured; Dose-Response

2017
8-Br-cADPR, a TRPM2 ion channel antagonist, inhibits renal ischemia-reperfusion injury.
    Journal of cellular physiology, 2019, Volume: 234, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Blood Urea Nitrogen; Calcium Channel Blockers; Catalas

2019
The effects of mebudipine on myocardial arrhythmia induced by ischemia-reperfusion injury in isolated rat heart.
    Cellular and molecular biology (Noisy-le-Grand, France), 2016, Nov-30, Volume: 62, Issue:13

    Topics: Animals; Arrhythmias, Cardiac; Creatine Kinase; Heart; Heart Rate; In Vitro Techniques; L-Lactate De

2016
Reactivity of brain parenchymal arterioles after ischemia and reperfusion.
    Microcirculation (New York, N.Y. : 1994), 2008, Volume: 15, Issue:6

    Topics: Animals; Arterioles; Brain; Brain Ischemia; Cerebrovascular Circulation; Enzyme Inhibitors; Male; Mi

2008
Neuroprotective effects of mebudipine and dibudipine on cerebral oxygen-glucose deprivation/reperfusion injury.
    European journal of pharmacology, 2009, May-21, Volume: 610, Issue:1-3

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Cell Survival; Cells,

2009
[Effects of ischemia/reperfusion on the phosphotyrosine proteins contents in hippocampus].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2001, Volume: 17, Issue:1

    Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Calcium Channels; Excitatory Amino Acid Antagonis

2001
Nifedipine treatment reduces brain damage after transient focal ischemia, possibly through its antioxidative effects.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:7

    Topics: Animals; Antioxidants; Brain; Brain Ischemia; Male; Mitochondria; Nifedipine; Oxidative Stress; Rats

2011
Calcium channel blockers reduce the effects of cigarette smoking on peripheral nerve ischemia/reperfusion injury.
    Annals of plastic surgery, 2013, Volume: 70, Issue:2

    Topics: Animals; Calcium Channel Blockers; Cotinine; Disease Models, Animal; Male; Nifedipine; Rats; Rats, W

2013
N-methyl-D-aspartate receptor and L-type voltage-gated Ca(2+) channel antagonists suppress the release of cytochrome c and the expression of procaspase-3 in rat hippocampus after global brain ischemia.
    Neuroscience letters, 2002, Aug-16, Volume: 328, Issue:3

    Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Calcium Channels, L-Type; Caspase 3; Caspase Inhi

2002
Effect of melatonin and nifedipine on some antioxidant enzymes and different energy fuels in the blood and brain of global ischemic rats.
    Journal of pineal research, 2002, Volume: 33, Issue:2

    Topics: 3-Hydroxybutyric Acid; Animals; Antioxidants; Blood; Brain; Calcium Channel Blockers; Disease Models

2002
Alpha-lipoic acid protects the retina against ischemia-reperfusion.
    Neuropharmacology, 2002, Volume: 43, Issue:6

    Topics: Anesthetics, Local; Animals; Antioxidants; Binding, Competitive; Brain-Derived Neurotrophic Factor;

2002
Ambient particulate matter affects cardiac recovery in a Langendorff ischemia model.
    Inhalation toxicology, 2006, Volume: 18, Issue:9

    Topics: Air Pollutants; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Coronary Circulation;

2006
Role of calcium channel blockers in postischemic lungs.
    Annals of the New York Academy of Sciences, 1994, Jun-17, Volume: 723

    Topics: Animals; Diltiazem; Hemodynamics; Lung; Nifedipine; Rabbits; Reperfusion Injury; Water-Electrolyte B

1994
Involvement of Na+-Ca2+ exchanger in reperfusion-induced delayed cell death of cultured rat astrocytes.
    The European journal of neuroscience, 1996, Volume: 8, Issue:5

    Topics: Amiloride; Animals; Astrocytes; Calcium; Calcium Channel Blockers; Carrier Proteins; Cell Death; Cel

1996
The potential synergistic effect of calcium channel blockers and alpha-tocopherol on gastric mucosal injury induced by ischaemia-reperfusion.
    European journal of gastroenterology & hepatology, 1996, Volume: 8, Issue:11

    Topics: Administration, Oral; Animals; Calcium Channel Blockers; Diltiazem; Disease Models, Animal; Dose-Res

1996
Hepatic ischemia-reperfusion injury modification during liver surgery in rats: pretreatment with nifedipine or misoprostol.
    Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 1995, Volume: 1, Issue:5

    Topics: Animals; Calcium Channel Blockers; Disease Models, Animal; Hepatectomy; Liver; Liver Diseases; Liver

1995
Microvascular permeability with sulfonylureas in normal and diabetic hamsters.
    Metabolism: clinical and experimental, 1997, Volume: 46, Issue:12 Suppl 1

    Topics: Animals; Calcium Channel Blockers; Calcium Channels; Capillary Permeability; Cricetinae; Dextrans; D

1997
Prevention of apoptosis reperfusion renal injury by calcium channel blockers.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1999, Volume: 51, Issue:3

    Topics: Animals; Apoptosis; Bepridil; Calcium Channel Blockers; Fendiline; Kidney; Kidney Tubules; Male; Nif

1999
Mechanisms of regulation of tyrosine phosphorylation of NMDA receptor subunit 2B after cerebral ischemia/reperfusion.
    Acta pharmacologica Sinica, 2000, Volume: 21, Issue:8

    Topics: Animals; Calcium Channel Blockers; Genistein; Gerbillinae; Hippocampus; Ischemic Attack, Transient;

2000
Changes and mechanisms of protein-tyrosine kinase and protein-tyrosine phosphatase activities after brain ischemia/reperfusion.
    Acta pharmacologica Sinica, 2000, Volume: 21, Issue:8

    Topics: Animals; Calcium Channel Blockers; Gerbillinae; Hippocampus; Ischemic Attack, Transient; Ketamine; N

2000
Nuclear factor kappaB activation is mediated by NMDA and non-NMDA receptor and L-type voltage-gated Ca(2+) channel following severe global ischemia in rat hippocampus.
    Brain research, 2002, Apr-12, Volume: 933, Issue:1

    Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Calcium Channels, L-Type; Cytoplasm; Excitatory A

2002
[Effect of ischemia/reperfusion on the phosphorylation of synaptosomal tyrosine of hippocampus of Mongolian gerbils].
    Sheng li xue bao : [Acta physiologica Sinica], 2000, Volume: 52, Issue:2

    Topics: Animals; Brain Ischemia; Calcium Channels, L-Type; Gerbillinae; Hippocampus; Ketamine; Nifedipine; P

2000
Topical flunarizine reduces IOP and protects the retina against ischemia-excitotoxicity.
    Investigative ophthalmology & visual science, 2002, Volume: 43, Issue:5

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Betaxolol; Calcium; Calcium Channel B

2002
Nifedipine and diltiazem reduce pulmonary edema formation during postischemic reperfusion of the rabbit lung.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1992, Volume: 192, Issue:2

    Topics: Animals; Diltiazem; Hemodynamics; Lung Transplantation; Nifedipine; Pulmonary Edema; Rabbits; Reperf

1992
Effects of verapamil and nifedipine on mechanisms of arrhythmia in an in vitro model of ischemia and reperfusion.
    Journal of cardiovascular pharmacology, 1991, Volume: 17, Issue:1

    Topics: Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Diastole; Dogs; Electrophysiology; Heart Co

1991
Ultrastructural changes in rat lungs after 48 h cold storage with and without reperfusion.
    International journal of experimental pathology, 1990, Volume: 71, Issue:4

    Topics: Allopurinol; Animals; Basement Membrane; Cryopreservation; Deferoxamine; Endothelium, Vascular; Epop

1990
Calcium-channel blockers and other factors influencing delayed function in renal allografts.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1990, Volume: 5, Issue:9

    Topics: Adult; Calcium Channel Blockers; Graft Survival; Humans; Immunosuppression Therapy; Kidney Transplan

1990
The effect of calcium antagonists on the activities of lipid metabolizing enzymes in the isolated ischaemically perfused and reperfused rat heart.
    Journal of molecular and cellular cardiology, 1990, Volume: 22, Issue:3

    Topics: Acyltransferases; Animals; Calcium; Calcium Channel Blockers; Coronary Disease; Diltiazem; Glycerol-

1990