Page last updated: 2024-11-01

nifedipine and Infant, Newborn, Diseases

nifedipine has been researched along with Infant, Newborn, Diseases in 7 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Infant, Newborn, Diseases: Diseases of newborn infants present at birth (congenital) or developing within the first month of birth. It does not include hereditary diseases not manifesting at birth or within the first 30 days of life nor does it include inborn errors of metabolism. Both HEREDITARY DISEASES and METABOLISM, INBORN ERRORS are available as general concepts.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the effectiveness of maintenance tocolytic therapy with oral nifedipine on the reduction of adverse neonatal outcomes and the prolongation of pregnancy by performing an individual patient data meta-analysis (IPDMA)."4.93Nifedipine maintenance tocolysis and perinatal outcome: an individual participant data meta-analysis. ( Carr, DB; Clark, AL; Dijkema, GH; El-Sayed, YY; Heida, KY; Lyell, DJ; Mahdy, ZA; McCowan, L; Mol, BW; Oudijk, MA; Parry, EC; Roos, C; Sayin, NC; Schuit, E; Uma, M; van der Post, J; van Vliet, E; Varol, GF, 2016)
"In threatened preterm labor, maintenance tocolysis with nifedipine, after an initial course of tocolysis and corticosteroids for 48 hours, may improve perinatal outcome."2.78Effect of maintenance tocolysis with nifedipine in threatened preterm labor on perinatal outcomes: a randomized controlled trial. ( Bloemenkamp, KW; Bolte, AC; Cornette, J; de Groot, CJ; Duvekot, JJ; Franssen, MT; Kok, JH; Kwee, A; Lotgering, FK; Merién, A; Mol, BW; Nij Bijvank, B; Opmeer, BC; Oudijk, MA; Papatsonis, DN; Porath, MM; Roos, C; Scheepers, HC; Scherjon, SA; Schuit, E; Sollie, KM; Spaanderman, ME; van der Post, JA; van Eyck, J; van Pampus, MG; Vijgen, SM; Willekes, C, 2013)
"Women in acute preterm labor with cervical dilatation 1-6 cm were randomized to receive one of three first-line tocolytic drugs."2.77Effect of antenatal tocolysis on neonatal outcomes. ( Briery, CM; Keiser, SD; Klauser, CK; Kosek, MA; Martin, RW; Morrison, JC, 2012)
"Nifedipine for treatment of preterm labor was associated with a lower incidence of neonatal morbidity than ritodrine."2.69Neonatal effects of nifedipine and ritodrine for preterm labor. ( Adèr, HJ; Bleker, OP; Dekker, GA; Kok, JH; Papatsonis, DN; van Geijn, HP, 2000)
"Treatment of preterm labor with beta-sympathomimetics has been questioned because of the many maternal and fetal complications associated with its use."2.67Comparison of nifedipine and ritodrine for the treatment of preterm labor. ( Bracero, LA; Kirshenbaum, N; Leikin, E; Tejani, N, 1991)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's1 (14.29)29.6817
2010's3 (42.86)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Dublin, S1
Idu, A1
Avalos, LA1
Cheetham, TC1
Easterling, TR1
Chen, L1
Holt, VL1
Nance, N1
Bider-Canfield, Z1
Neugebauer, RS1
Reynolds, K1
Badon, SE1
Shortreed, SM1
van Vliet, E1
Dijkema, GH1
Schuit, E2
Heida, KY1
Roos, C2
van der Post, J1
Parry, EC1
McCowan, L1
Lyell, DJ1
El-Sayed, YY1
Carr, DB1
Clark, AL1
Mahdy, ZA1
Uma, M1
Sayin, NC1
Varol, GF1
Mol, BW2
Oudijk, MA2
Klauser, CK1
Briery, CM1
Keiser, SD1
Martin, RW1
Kosek, MA1
Morrison, JC1
Spaanderman, ME1
Bloemenkamp, KW1
Bolte, AC1
Cornette, J1
Duvekot, JJ1
van Eyck, J1
Franssen, MT1
de Groot, CJ1
Kok, JH2
Kwee, A1
Merién, A1
Nij Bijvank, B1
Opmeer, BC1
van Pampus, MG1
Papatsonis, DN2
Porath, MM1
Scheepers, HC1
Scherjon, SA1
Sollie, KM1
Vijgen, SM1
Willekes, C1
van der Post, JA1
Lotgering, FK1
Patole, SK1
Finer, NN1
van Geijn, HP1
Bleker, OP1
Adèr, HJ1
Dekker, GA1
Bracero, LA1
Leikin, E1
Kirshenbaum, N1
Tejani, N1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Vaginal Indomethacin Versus Oral Nifedipine for Preterm Labor; a Randomized Controlled Trial[NCT04404686]Phase 2/Phase 3300 participants (Anticipated)Interventional2020-10-31Not yet recruiting
Randomized Double-Blinded Trial of Magnesium Sulfate Tocolysis Versus Nifedipine Tocolysis in Women With Preterm Labor Between 24 to 32 6/7 Weeks' Gestation[NCT00306462]33 participants (Actual)Interventional2006-03-31Terminated (stopped due to No enrollment in past year, lack of interest)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for nifedipine and Infant, Newborn, Diseases

ArticleYear
Nifedipine maintenance tocolysis and perinatal outcome: an individual participant data meta-analysis.
    BJOG : an international journal of obstetrics and gynaecology, 2016, Volume: 123, Issue:11

    Topics: Adult; Female; Gestational Age; Humans; Infant, Newborn; Infant, Newborn, Diseases; Nifedipine; Peri

2016
Experimental and clinical effects of magnesium infusion in the treatment of neonatal pulmonary hypertension.
    Magnesium research, 1995, Volume: 8, Issue:4

    Topics: Animals; Blood Coagulation; Calcium Channel Blockers; Cyclic AMP; Cyclic GMP; Disease Models, Animal

1995

Trials

4 trials available for nifedipine and Infant, Newborn, Diseases

ArticleYear
Effect of antenatal tocolysis on neonatal outcomes.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2012, Volume: 25, Issue:12

    Topics: Female; Gestational Age; Humans; Indomethacin; Infant, Newborn; Infant, Newborn, Diseases; Magnesium

2012
Effect of maintenance tocolysis with nifedipine in threatened preterm labor on perinatal outcomes: a randomized controlled trial.
    JAMA, 2013, Jan-02, Volume: 309, Issue:1

    Topics: Adult; Double-Blind Method; Drug Administration Schedule; Enterocolitis, Necrotizing; Female; Fetal

2013
Neonatal effects of nifedipine and ritodrine for preterm labor.
    Obstetrics and gynecology, 2000, Volume: 95, Issue:4

    Topics: Adult; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Nifedipine; Obstetric Labor

2000
Comparison of nifedipine and ritodrine for the treatment of preterm labor.
    American journal of perinatology, 1991, Volume: 8, Issue:6

    Topics: Adult; Birth Weight; Female; Fetus; Humans; Infant, Newborn; Infant, Newborn, Diseases; Nifedipine;

1991

Other Studies

1 other study available for nifedipine and Infant, Newborn, Diseases

ArticleYear
Maternal and neonatal outcomes of antihypertensive treatment in pregnancy: A retrospective cohort study.
    PloS one, 2022, Volume: 17, Issue:5

    Topics: Antihypertensive Agents; Birth Weight; Female; Humans; Hypertension, Pregnancy-Induced; Infant; Infa

2022