nifedipine has been researched along with Hypotension in 95 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We sought to compare the efficacy of intravenously administered hydralazine and oral nifedipine for acute blood pressure control in acute hypertensive emergency of pregnancy." | 9.24 | Hydralazine vs nifedipine for acute hypertensive emergency in pregnancy: a randomized controlled trial. ( Gupta, A; Sharma, C; Soni, A; Verma, A; Verma, S, 2017) |
| "Readily available echocardiographic parameters in patients with PPH are predictive of nifedipine-induced hypotension, and can be used to select patients in whom a trial of nifedipine should be avoided." | 9.09 | Echocardiographic predictors of an adverse response to a nifedipine trial in primary pulmonary hypertension: diminished left ventricular size and leftward ventricular septal bowing. ( Armstrong, WF; Bach, DS; Bossone, E; Ricciardi, MJ; Rubenfire, M, 1999) |
| "Nifedipine administration for hypertensive emergencies can induce neurological and cardiac events due to abrupt hypotension." | 8.80 | Hypotension and coronary events on nifedipine: reassessing nifedipine safety. ( , 1998) |
| "In patients with coronary disease, the use of short-acting nifedipine in moderate to high doses causes an increase in total mortality." | 8.79 | Nifedipine. Dose-related increase in mortality in patients with coronary heart disease. ( Furberg, CD; Meyer, JV; Psaty, BM, 1995) |
| " This report describes a case of severe bradyarrhythmia during anesthetic induction with propofol, midazolam, sufentanil, and vecuronium." | 8.02 | Bradyarrhythmia and hypotension during anesthetic induction-reconsideration of nifedipine: a case report. ( Zhang, X, 2021) |
| " Antimicrobial therapy with voriconazole lowered the blood pressure, and then clarithromycin further lowered it through the excessively elevated nifedipine concentration, leading to ischemic acute kidney injury." | 7.85 | Acute Kidney Injury from Excessive Potentiation of Calcium-channel Blocker via Synergistic CYP3A4 Inhibition by Clarithromycin Plus Voriconazole. ( Abe, T; Ito, S; Maruyama, K; Mishima, E; Nakazawa, T, 2017) |
| "The purpose of this study was to assess the utility of inhaled nitric oxide (NO), a selective pulmonary vasodilator, for predicting the safety and acute hemodynamic response to high-dose oral nifedipine in primary pulmonary hypertension (PPH)." | 7.70 | Inhaled nitric oxide in primary pulmonary hypertension: a safe and effective agent for predicting response to nifedipine. ( Knight, BP; Martinez, FJ; Ricciardi, MJ; Rubenfire, M, 1998) |
| "The purpose of the present study was to examine the effect of nilvadipine (a dihydropyridine-type calcium entry blocker) on the cerebral circulation, experimental models of cerebral ischemia were used to measure abrupt changes in the cortical cerebral blood flow (CBF) at the 'penumbra' (the boundary region between the anterior cerebral artery (ACA) and the middle cerebral artery (MCA))." | 7.69 | Effects of nilvadipine (a dihydropyridine-type calcium entry blocker) on cerebral blood flow in acute experimental brain ischemia in rats. ( Fujii, K; Maruyama, S; Miyasaka, Y; Nagai, S; Tanaka, R, 1996) |
| "Two patients with pheochromocytoma initially responded to oral or sublingual nifedipine with marked reduction in systolic blood pressure (range 50-160 mmHg) without concomitant increment in the heart rate or clinical consequences." | 7.68 | Precipitous hypotension after nifedipine in pheochromocytoma: report of 2 cases. ( Rujiwanichkul, K; Tantawanichpisal, D; Yipintsoi, T, 1993) |
| "Glucagon relieves calcium channel blocker-induced hypotension in animal studies." | 7.68 | Amelioration of nifedipine poisoning associated with glucagon therapy. ( Ekins, BR; Frye, G; Khasigian, PA; Mullen, JT; Walter, FG, 1993) |
| "We have presented a case in which nifedipine-induced hypotension in a patient receiving beta blocker and nitrate therapy precipitated mesenteric angina, leading to emergency exploratory celiotomy." | 7.67 | Nifedipine-induced hypotension and mesenteric ischemia. ( Deppe, SA; Elliott, BM; Goglin, WK, 1989) |
| "Hypotension was defined as a decrease in systolic or diastolic blood pressure of 15 mmHg or more." | 5.37 | Hypotension in normotensive pregnant women treated with nifedipine as a tocolytic drug. ( Luewan, S; Mahathep, R; Tongsong, T, 2011) |
| " There have been few case reports of adverse events in children." | 5.31 | Evaluation of the safety of short-acting nifedipine in children with hypertension. ( Deming, DD; Egger, DW; Hamada, N; Perkin, RM; Sahney, S, 2002) |
| "We sought to compare the efficacy of intravenously administered hydralazine and oral nifedipine for acute blood pressure control in acute hypertensive emergency of pregnancy." | 5.24 | Hydralazine vs nifedipine for acute hypertensive emergency in pregnancy: a randomized controlled trial. ( Gupta, A; Sharma, C; Soni, A; Verma, A; Verma, S, 2017) |
| "Readily available echocardiographic parameters in patients with PPH are predictive of nifedipine-induced hypotension, and can be used to select patients in whom a trial of nifedipine should be avoided." | 5.09 | Echocardiographic predictors of an adverse response to a nifedipine trial in primary pulmonary hypertension: diminished left ventricular size and leftward ventricular septal bowing. ( Armstrong, WF; Bach, DS; Bossone, E; Ricciardi, MJ; Rubenfire, M, 1999) |
| "The acute effects of nifedipine withdrawal were studied in 81 patients with angina at rest who had completed a prospective, double-blind, randomized trial of nifedipine versus placebo." | 5.05 | Safety of acute calcium antagonist withdrawal: studies in patients with unstable angina withdrawn from nifedipine. ( Gerstenblith, G; Gottlieb, SO, 1985) |
| "The present evidence suggests similar efficacy between nifedipine, hydralazine and labetalol in the treatment of severe hypertension in pregnancy." | 4.98 | Drugs for treating severe hypertension in pregnancy: a network meta-analysis and trial sequential analysis of randomized clinical trials. ( Sequeira, RP; Sridharan, K, 2018) |
| "Nifedipine administration for hypertensive emergencies can induce neurological and cardiac events due to abrupt hypotension." | 4.80 | Hypotension and coronary events on nifedipine: reassessing nifedipine safety. ( , 1998) |
| "In patients with coronary disease, the use of short-acting nifedipine in moderate to high doses causes an increase in total mortality." | 4.79 | Nifedipine. Dose-related increase in mortality in patients with coronary heart disease. ( Furberg, CD; Meyer, JV; Psaty, BM, 1995) |
| " This report describes a case of severe bradyarrhythmia during anesthetic induction with propofol, midazolam, sufentanil, and vecuronium." | 4.02 | Bradyarrhythmia and hypotension during anesthetic induction-reconsideration of nifedipine: a case report. ( Zhang, X, 2021) |
| "BackgroundIn the clinical setting, verapamil is contraindicated in neonates and infants, because of the perceived risk of hypotension or bradyarrhythmia." | 3.88 | Postnatal developmental changes in the sensitivity of L-type Ca ( Ding, WG; Hoshino, S; Maruo, Y; Matsuura, H; Nakagawa, M; Omatsu-Kanbe, M; Sagawa, H; Yoshioka, K, 2018) |
| " Antimicrobial therapy with voriconazole lowered the blood pressure, and then clarithromycin further lowered it through the excessively elevated nifedipine concentration, leading to ischemic acute kidney injury." | 3.85 | Acute Kidney Injury from Excessive Potentiation of Calcium-channel Blocker via Synergistic CYP3A4 Inhibition by Clarithromycin Plus Voriconazole. ( Abe, T; Ito, S; Maruyama, K; Mishima, E; Nakazawa, T, 2017) |
| "Nifedipine immediate release (IR) is a short-acting dihydropyridine calcium channel blocker historically used for hypertensive crisis, but its use has decreased because of reports of adverse reactions such as myocardial infarction (MI), arrhythmias, and stroke." | 3.83 | Safety of Immediate-Release Nifedipine. ( Benken, ST; Means, L; Tesoro, EP, 2016) |
| "A 37-year-old woman presented with persistent hypotension and noncardiogenic pulmonary edema after massive nifedipine overdose." | 3.71 | Continuous calcium chloride infusion for massive nifedipine overdose. ( Lam, YM; Lau, CP; Tse, HF, 2001) |
| "Nifedipine is a prototypical dihydropyridine calcium channel "blocker" that can cause hypotension and cardiac conduction abnormalities." | 3.70 | Fatal nifedipine ingestions in children. ( Dougherty, T; Greene, T; Lee, DC; Pearigen, P, 2000) |
| "The purpose of this study was to assess the utility of inhaled nitric oxide (NO), a selective pulmonary vasodilator, for predicting the safety and acute hemodynamic response to high-dose oral nifedipine in primary pulmonary hypertension (PPH)." | 3.70 | Inhaled nitric oxide in primary pulmonary hypertension: a safe and effective agent for predicting response to nifedipine. ( Knight, BP; Martinez, FJ; Ricciardi, MJ; Rubenfire, M, 1998) |
| "The purpose of the present study was to examine the effect of nilvadipine (a dihydropyridine-type calcium entry blocker) on the cerebral circulation, experimental models of cerebral ischemia were used to measure abrupt changes in the cortical cerebral blood flow (CBF) at the 'penumbra' (the boundary region between the anterior cerebral artery (ACA) and the middle cerebral artery (MCA))." | 3.69 | Effects of nilvadipine (a dihydropyridine-type calcium entry blocker) on cerebral blood flow in acute experimental brain ischemia in rats. ( Fujii, K; Maruyama, S; Miyasaka, Y; Nagai, S; Tanaka, R, 1996) |
| "We evaluated the effect of different vasodilators on ventricular end-systolic stress by investigating the impact of sodium nitroprusside, nifedipine, and hydralazine on blood pressure, aortic stiffness, and wave reflection during drug-induced hypotension (to 80 mm Hg mean blood pressure) in normotensive (central aortic mean blood pressure, 116 to 119 mm Hg; systolic pressure, 133 to 137 mm Hg), nonanesthetized, unrestrained rats." | 3.69 | Vasodilators, aortic elasticity, and ventricular end-systolic stress in nonanesthetized unrestrained rats. ( Atkinson, J; Duvivier, C; Lartaud-Idjouadiene, I; Marque, V; Niederhoffer, N; Peslin, R, 1997) |
| "Glucagon relieves calcium channel blocker-induced hypotension in animal studies." | 3.68 | Amelioration of nifedipine poisoning associated with glucagon therapy. ( Ekins, BR; Frye, G; Khasigian, PA; Mullen, JT; Walter, FG, 1993) |
| "Hypotension, sinus node suppression, and dysrhythmias often occur with calcium channel blocker overdoses, but atrioventricular nodal block occurs more often with verapamil (chi 2 test, P < ." | 3.68 | A one-year evaluation of calcium channel blocker overdoses: toxicity and treatment. ( Borys, D; Ramoska, EA; Spiller, HA; Winter, M, 1993) |
| "Two patients with pheochromocytoma initially responded to oral or sublingual nifedipine with marked reduction in systolic blood pressure (range 50-160 mmHg) without concomitant increment in the heart rate or clinical consequences." | 3.68 | Precipitous hypotension after nifedipine in pheochromocytoma: report of 2 cases. ( Rujiwanichkul, K; Tantawanichpisal, D; Yipintsoi, T, 1993) |
| "Concentrations of gamma-aminobutyric acid (GABA) and other amino acids were measured in microdissected areas of the rostral ventro-lateral medulla (RVL), nucleus tractus solitarii (NTS) and caudal ventrolateral medulla (CVL) of the rat, and effects on the amino acid levels, of hypotension induced by hexamethonium and nifedipine were examined." | 3.68 | Hypotension decreases GABA levels in brainstem regions of the rat. ( Kihara, M; Kubo, T; Misu, Y, 1990) |
| "We have presented a case in which nifedipine-induced hypotension in a patient receiving beta blocker and nitrate therapy precipitated mesenteric angina, leading to emergency exploratory celiotomy." | 3.67 | Nifedipine-induced hypotension and mesenteric ischemia. ( Deppe, SA; Elliott, BM; Goglin, WK, 1989) |
| "Hypotension induced by nifedipine and chlorpromazine is discussed, together with the role of noradrenaline in the correction of this problem, which was resistant to other forms of therapy." | 3.67 | A plea for noradrenaline. ( Crosse, MM; Stuart-Taylor, ME, 1989) |
| "001), but differential dosing effects were not observed." | 1.42 | Hemodynamic effects of nifedipine tocolysis. ( Burlingame, J; Kaneshiro, B; Yamasato, K, 2015) |
| "Hypotension was defined as a decrease in systolic or diastolic blood pressure of 15 mmHg or more." | 1.37 | Hypotension in normotensive pregnant women treated with nifedipine as a tocolytic drug. ( Luewan, S; Mahathep, R; Tongsong, T, 2011) |
| "A 31-year-old woman developed bilateral posterior ischemic optic neuropathy and infarctions of the cerebral arterial border zones and spinal cord after correction of malignant hypertension." | 1.35 | Simultaneous posterior ischemic optic neuropathy, cerebral border zone infarction, and spinal cord infarction after correction of malignant hypertension. ( An, SJ; Choi, JH; Choi, KD; Kim, HJ; Kim, JS; Lee, JE, 2008) |
| "Nifedipine and CGP 28392 treatment of nonpregnant and pregnant animals, respectively, did not modify the response of aortic rings to KCl." | 1.31 | Calcium channels contribute to the decrease in blood pressure of pregnant rats. ( Brochu, M; Cadorette, C; Poterek, M; Simaan, M; St-Louis, J, 2002) |
| " There have been few case reports of adverse events in children." | 1.31 | Evaluation of the safety of short-acting nifedipine in children with hypertension. ( Deming, DD; Egger, DW; Hamada, N; Perkin, RM; Sahney, S, 2002) |
| "The hypotension was also unchanged after autonomic ganglion or angiotensin-converting-enzyme blockade." | 1.30 | Hypotensive effect of the methanolic extract of Mimusops elengi in normotensive rats. ( Behbahanian, S; Dar, A; Jahan, N; Malik, A, 1999) |
| " The rats were observed for toxic signs and survival over a period of 15 days." | 1.29 | Reversal of acute theophylline toxicity by calcium channel blockers in dogs and rats. ( Alleva, FR; Balazs, T; Joseph, X; Vick, JA; Whitehurst, VE; Zhang, J, 1996) |
| "Nifedipine (1 mg/kg ip) was equally effective in preventing the increase in MBP caused by endothelin, norepinephrine, or ANG II." | 1.28 | Efficacy of nifedipine to prevent systemic and renal vasoconstrictor effects of endothelin. ( Anania, V; Demontis, MP; Madeddu, P; Manunta, P; Pazzola, A; Soro, A; Tonolo, G; Troffa, C; Varoni, MV; Yang, XP, 1990) |
| " The mean nontoxic dose was 320 mg, whereas the mean toxic ingestion was 3." | 1.28 | Calcium channel blocker toxicity. ( Myers, A; Ramoska, EA; Spiller, HA, 1990) |
| "Nifedipine is a calcium channel blocker which results in relaxation of smooth muscle." | 1.28 | Nifedipine inhibits cholecystokinin-induced gallbladder contraction. ( Arzoumanian, A; Clas, D; Fried, GM; Hould, FS; Rosenthall, L, 1989) |
| "Arterial hypotension has been demonstrated after left ventriculography using currently available ionic contrast agents." | 1.27 | Potentiation by nifedipine and diltiazem of the hypotensive response after contrast angiography. ( Axelrod, R; Gertz, EW; Langberg, JJ; Morris, DL; Wexman, M; Wisneski, JA, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 36 (37.89) | 18.7374 |
| 1990's | 30 (31.58) | 18.2507 |
| 2000's | 14 (14.74) | 29.6817 |
| 2010's | 11 (11.58) | 24.3611 |
| 2020's | 4 (4.21) | 2.80 |
| Authors | Studies |
|---|---|
| Seto, SL | 1 |
| Barra, ME | 1 |
| Hamidi, A | 1 |
| Sin, JH | 1 |
| Devine, LT | 1 |
| Soares, C | 1 |
| Gilson, M | 1 |
| Drobek, HH | 1 |
| Porwolik, M | 1 |
| Pietrauszka, K | 1 |
| Miziołek, B | 1 |
| Bergler-Czop, B | 1 |
| Brzezińska-Wcisło, L | 1 |
| Zhang, X | 1 |
| Mishima, E | 1 |
| Maruyama, K | 1 |
| Nakazawa, T | 1 |
| Abe, T | 1 |
| Ito, S | 1 |
| Shah, SP | 1 |
| Self, TH | 1 |
| Bradsher, RW | 1 |
| Owens, RE | 1 |
| Sharma, C | 1 |
| Soni, A | 1 |
| Gupta, A | 1 |
| Verma, A | 1 |
| Verma, S | 1 |
| Sagawa, H | 1 |
| Hoshino, S | 1 |
| Yoshioka, K | 1 |
| Ding, WG | 1 |
| Omatsu-Kanbe, M | 1 |
| Nakagawa, M | 1 |
| Maruo, Y | 1 |
| Matsuura, H | 1 |
| Sridharan, K | 1 |
| Sequeira, RP | 1 |
| Ngamprasertwong, P | 1 |
| Habli, M | 1 |
| Boat, A | 1 |
| Lim, FY | 1 |
| Esslinger, H | 1 |
| Ding, L | 1 |
| Sadhasivam, S | 1 |
| Yamasato, K | 1 |
| Burlingame, J | 1 |
| Kaneshiro, B | 1 |
| Khoo, F | 1 |
| Mathur, M | 1 |
| Means, L | 1 |
| Benken, ST | 1 |
| Tesoro, EP | 1 |
| Choi, JH | 1 |
| Choi, KD | 1 |
| Kim, JS | 1 |
| Kim, HJ | 1 |
| Lee, JE | 1 |
| An, SJ | 1 |
| Kato, J | 1 |
| Mori, T | 1 |
| Nakamura, Y | 1 |
| Sakurai, M | 1 |
| Aisa, Y | 1 |
| Ikeda, Y | 1 |
| Okamoto, S | 1 |
| Bastos, JF | 1 |
| Moreira, IJ | 1 |
| Ribeiro, TP | 1 |
| Medeiros, IA | 1 |
| Antoniolli, AR | 1 |
| De Sousa, DP | 1 |
| Santos, MR | 1 |
| Luewan, S | 1 |
| Mahathep, R | 1 |
| Tongsong, T | 1 |
| Fryer, RM | 1 |
| Preusser, LC | 1 |
| Calzadilla, SV | 1 |
| Hu, Y | 1 |
| Xu, H | 1 |
| Marsh, KC | 1 |
| Cox, BF | 1 |
| Lin, CT | 1 |
| Gopalakrishnan, M | 1 |
| Reinhart, GA | 1 |
| van Veen, AJ | 1 |
| Pelinck, MJ | 1 |
| van Pampus, MG | 1 |
| Erwich, JJ | 1 |
| Kandysamy, V | 1 |
| Thomson, AJ | 1 |
| Papatsonis, DN | 1 |
| Carbonne, B | 1 |
| Dekker, GA | 1 |
| Flenady, V | 1 |
| King, JF | 1 |
| Johnson, KA | 1 |
| Mason, GC | 1 |
| Dean, S | 1 |
| Kendall, MJ | 1 |
| Iaina, A | 1 |
| Eliahou, HE | 1 |
| Covinsky, JO | 1 |
| Hamburger, SC | 1 |
| Rubin, LJ | 1 |
| Jee, LD | 1 |
| Opie, LH | 3 |
| Frampton, MW | 1 |
| Proctor, HJ | 1 |
| Palladino, GW | 1 |
| Fillipo, D | 1 |
| Sanders, R | 1 |
| Gygax, P | 1 |
| Wiernsperger, N | 1 |
| Staffurth, JS | 1 |
| Emery, P | 1 |
| Buxton, AE | 1 |
| Hirshfeld, JW | 1 |
| Untereker, WJ | 1 |
| Goldberg, S | 1 |
| Harken, AH | 1 |
| Stephenson, LW | 1 |
| Edie, RN | 1 |
| Resnekov, L | 1 |
| Karlsberg, RP | 1 |
| Aronow, WS | 1 |
| Kopf, GS | 1 |
| Riba, A | 1 |
| Zito, R | 1 |
| Brooks, N | 1 |
| Cattell, M | 1 |
| Pidgeon, J | 1 |
| Balcon, R | 1 |
| White, DA | 1 |
| Messerli, FH | 2 |
| Furberg, CD | 1 |
| Psaty, BM | 1 |
| Meyer, JV | 1 |
| Stewart, DJ | 1 |
| Evans, WK | 1 |
| Logan, D | 1 |
| Impey, L | 1 |
| Tantawanichpisal, D | 1 |
| Rujiwanichkul, K | 1 |
| Yipintsoi, T | 1 |
| Goswami, G | 1 |
| Gurtoo, A | 1 |
| Mehd, US | 1 |
| Nanavati, PR | 1 |
| Ravichandran, P | 1 |
| Bhatnagar, MK | 2 |
| Ramoska, EA | 2 |
| Spiller, HA | 2 |
| Winter, M | 1 |
| Borys, D | 1 |
| Walter, FG | 1 |
| Frye, G | 1 |
| Mullen, JT | 1 |
| Ekins, BR | 1 |
| Khasigian, PA | 1 |
| Whitehurst, VE | 1 |
| Joseph, X | 1 |
| Vick, JA | 1 |
| Alleva, FR | 1 |
| Zhang, J | 1 |
| Balazs, T | 1 |
| Balakumaran, A | 1 |
| Campbell, GA | 1 |
| Moslen, MT | 1 |
| Tanaka, R | 1 |
| Miyasaka, Y | 1 |
| Maruyama, S | 1 |
| Nagai, S | 1 |
| Fujii, K | 1 |
| Niederhoffer, N | 1 |
| Marque, V | 1 |
| Lartaud-Idjouadiene, I | 1 |
| Duvivier, C | 1 |
| Peslin, R | 1 |
| Atkinson, J | 1 |
| Tomiyama, H | 1 |
| Watanabe, G | 1 |
| Siojima, K | 1 |
| Nishikawa, E | 1 |
| Nakayama, T | 1 |
| Yamamoto, A | 1 |
| Ishikawa, Y | 1 |
| Yoshida, H | 1 |
| Doba, N | 1 |
| Truttmann, AC | 1 |
| Zehnder-Schlapbach, S | 1 |
| Bianchetti, MG | 1 |
| Ricciardi, MJ | 2 |
| Knight, BP | 1 |
| Martinez, FJ | 1 |
| Rubenfire, M | 2 |
| Wong, CH | 1 |
| Wu, WH | 1 |
| Zbuzek, VK | 1 |
| Grossman, E | 1 |
| Barst, RJ | 1 |
| Bossone, E | 1 |
| Bach, DS | 1 |
| Armstrong, WF | 1 |
| Papadopoulos, J | 1 |
| O'Neil, MG | 1 |
| Porpiglia, F | 1 |
| Destefanis, P | 1 |
| Fiori, C | 1 |
| Fontana, D | 1 |
| Lee, DC | 1 |
| Greene, T | 1 |
| Dougherty, T | 1 |
| Pearigen, P | 1 |
| Lam, YM | 1 |
| Tse, HF | 1 |
| Lau, CP | 1 |
| Riley, CK | 1 |
| Terezhalmy, GT | 1 |
| Simaan, M | 1 |
| Cadorette, C | 1 |
| Poterek, M | 1 |
| St-Louis, J | 1 |
| Brochu, M | 1 |
| Egger, DW | 1 |
| Deming, DD | 1 |
| Hamada, N | 1 |
| Perkin, RM | 1 |
| Sahney, S | 1 |
| Dar, A | 1 |
| Behbahanian, S | 1 |
| Malik, A | 1 |
| Jahan, N | 1 |
| Goel, A | 1 |
| Malhotra, M | 1 |
| Vashishta, A | 1 |
| Verma, NP | 1 |
| Dupuis, JY | 1 |
| Nathan, HJ | 1 |
| Laganière, S | 1 |
| Woodmansey, P | 1 |
| Channer, KS | 1 |
| Ferder, L | 1 |
| Daccordi, H | 1 |
| Martello, M | 1 |
| Panzalis, M | 1 |
| Inserra, F | 1 |
| Kubo, T | 1 |
| Kihara, M | 1 |
| Misu, Y | 1 |
| Madeddu, P | 1 |
| Yang, XP | 1 |
| Anania, V | 1 |
| Troffa, C | 1 |
| Pazzola, A | 1 |
| Soro, A | 1 |
| Manunta, P | 1 |
| Tonolo, G | 1 |
| Demontis, MP | 1 |
| Varoni, MV | 1 |
| Myers, A | 1 |
| Guazzi, MD | 1 |
| Alimento, M | 1 |
| Berti, M | 1 |
| Fiorentini, C | 1 |
| Galli, C | 1 |
| Tamborini, G | 1 |
| Goglin, WK | 1 |
| Elliott, BM | 1 |
| Deppe, SA | 1 |
| Stuart-Taylor, ME | 1 |
| Crosse, MM | 1 |
| Clas, D | 1 |
| Hould, FS | 1 |
| Rosenthall, L | 1 |
| Arzoumanian, A | 1 |
| Fried, GM | 1 |
| Shettigar, UR | 1 |
| Loungani, R | 1 |
| Handley, DA | 1 |
| Van Valen, RG | 1 |
| Melden, MK | 1 |
| Saunders, RN | 1 |
| Seino, M | 1 |
| Abe, K | 1 |
| Nushiro, N | 1 |
| Yoshinaga, K | 1 |
| Toivonen, LK | 1 |
| Pohjola-Sintonen, S | 1 |
| Herrington, DM | 1 |
| Insley, BM | 1 |
| Weinmann, GG | 1 |
| Wachter, RM | 1 |
| Gottlieb, SO | 1 |
| Gerstenblith, G | 1 |
| Ellrodt, AG | 1 |
| Ault, MJ | 1 |
| Sia, ST | 1 |
| MacDonald, PS | 1 |
| Triester, B | 1 |
| Oliver, LE | 1 |
| Horowitz, JD | 1 |
| Goble, AJ | 1 |
| Aromatorio, GJ | 1 |
| Uretsky, BF | 1 |
| Reddy, PS | 1 |
| Miller, AP | 1 |
| Falcone, RE | 1 |
| Nappi, J | 1 |
| Redmon, HA | 1 |
| Sachs, R | 1 |
| Morris, DL | 1 |
| Wisneski, JA | 1 |
| Gertz, EW | 1 |
| Wexman, M | 1 |
| Axelrod, R | 1 |
| Langberg, JJ | 1 |
| Muramoto, A | 1 |
| Caldwell, J | 1 |
| Albert, RK | 1 |
| Lakshminarayan, S | 1 |
| Butler, J | 1 |
| Galiè, N | 1 |
| Sanguinetti, M | 1 |
| Marrozzini, C | 1 |
| Magnani, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Calcium Channel Blockers in Nitric Oxide Non-responder Pulmonary Arterial Hypertension.[NCT01645826] | 0 participants (Actual) | Interventional | 2012-07-31 | Withdrawn (stopped due to no participants agreed to enroll since study start) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for nifedipine and Hypotension
| Article | Year |
|---|---|
What is the Best Way to Treat Patients with Raynaud's Phenomenon and a Tendency towards Hypotension?
Topics: Antihypertensive Agents; Calcium Channel Blockers; Humans; Hypotension; Losartan; Nifedipine; Nitrog | 2020 |
Drugs for treating severe hypertension in pregnancy: a network meta-analysis and trial sequential analysis of randomized clinical trials.
Topics: Antihypertensive Agents; Dose-Response Relationship, Drug; Female; Headache; Humans; Hydralazine; Hy | 2018 |
From beta blockers to Ca2+ blockers in hypertension: a review.
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Coronary Circulation; Drug Therapy, Combinati | 1982 |
Slow channel blockers.
Topics: Angina Pectoris; Arrhythmias, Cardiac; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Cons | 1983 |
Cardiovascular effects of vasodilator therapy for pulmonary arterial hypertension.
Topics: Cardiac Output; Echocardiography; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmonary; Hypote | 1983 |
Nifedipine. Dose-related increase in mortality in patients with coronary heart disease.
Topics: Angina Pectoris; Arrhythmias, Cardiac; Calcium Channel Blockers; Confidence Intervals; Coronary Dise | 1995 |
Hypotension and coronary events on nifedipine: reassessing nifedipine safety.
Topics: Angina, Unstable; Calcium Channel Blockers; Contraindications; Drug Evaluation; France; Humans; Hype | 1998 |
Do no harm.
Topics: Calcium Channel Blockers; Contraindications; Echocardiography; Heart Septum; Heart Ventricles; Human | 1999 |
The patient with hypertension.
Topics: Anesthesia, Dental; Calcium Channel Blockers; Coronary Disease; Dental Care for Chronically Ill; Eme | 2001 |
7 trials available for nifedipine and Hypotension
| Article | Year |
|---|---|
Hydralazine vs nifedipine for acute hypertensive emergency in pregnancy: a randomized controlled trial.
Topics: Acute Disease; Adolescent; Adult; Apgar Score; Double-Blind Method; Emergencies; Female; Humans; Hyd | 2017 |
Relationship between calcium channel antagonists and nocturnal hypotension and autonomic imbalance in patients with a previous myocardial infarction.
Topics: Adult; Aged; Angina Pectoris; Autonomic Nervous System; Blood Pressure; Blood Pressure Monitoring, A | 1998 |
Echocardiographic predictors of an adverse response to a nifedipine trial in primary pulmonary hypertension: diminished left ventricular size and leftward ventricular septal bowing.
Topics: Administration, Oral; Adult; Blood Pressure; Calcium Channel Blockers; Echocardiography; Female; Hea | 1999 |
Effectiveness of nifedipine and deflazacort in the management of distal ureter stones.
Topics: Administration, Oral; Adult; Aged; Anti-Inflammatory Agents; Arrhythmias, Cardiac; Calcium Channel B | 2000 |
Intravenous nifedipine for prevention of myocardial ischaemia after coronary revascularization.
Topics: Blood Pressure; Coronary Artery Bypass; Creatine Kinase; Electrocardiography; Electrocardiography, A | 1992 |
Angiotensin converting enzyme inhibitors versus calcium antagonists in the treatment of diabetic hypertensive patients.
Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Creatinine; Diab | 1992 |
Safety of acute calcium antagonist withdrawal: studies in patients with unstable angina withdrawn from nifedipine.
Topics: Angina Pectoris; Angina, Unstable; Coronary Artery Bypass; Coronary Disease; Double-Blind Method; El | 1985 |
79 other studies available for nifedipine and Hypotension
| Article | Year |
|---|---|
Efficacy and Safety of Immediate-Release Nifedipine in Critically Ill Patients.
Topics: Antihypertensive Agents; Blood Pressure; Critical Illness; Humans; Hypertension; Hypotension; Nifedi | 2023 |
Nifedipine-Induced Shock in Pregnancy With Aortic Stenosis.
Topics: Aortic Valve Stenosis; Calcium Gluconate; Chest Pain; Electrocardiography; Female; Fetofetal Transfu | 2020 |
Bradyarrhythmia and hypotension during anesthetic induction-reconsideration of nifedipine: a case report.
Topics: Anesthetics; Bradycardia; Humans; Hypotension; Nifedipine; Propofol | 2021 |
Acute Kidney Injury from Excessive Potentiation of Calcium-channel Blocker via Synergistic CYP3A4 Inhibition by Clarithromycin Plus Voriconazole.
Topics: Acute Kidney Injury; Aged; Anti-Bacterial Agents; Blood Pressure; Calcium Channel Blockers; Clarithr | 2017 |
Clarithromycin-nifedipine-induced acute kidney injury.
Topics: Acute Kidney Injury; Aged, 80 and over; Clarithromycin; Drug Interactions; Female; Humans; Hypotensi | 2017 |
Postnatal developmental changes in the sensitivity of L-type Ca
Topics: Animals; Bradycardia; Calcium Channel Blockers; Calcium Channels, L-Type; Diltiazem; Disease Models, | 2018 |
Maternal hypotension during fetoscopic surgery: incidence and its impact on fetal survival outcomes.
Topics: Adult; Cohort Studies; Female; Fetal Death; Fetofetal Transfusion; Fetoscopy; Humans; Hypotension; I | 2013 |
Hemodynamic effects of nifedipine tocolysis.
Topics: Adolescent; Adult; Blood Pressure; Female; Heart Rate; Humans; Hypotension; Nifedipine; Pregnancy; R | 2015 |
Severe resistant maternal hypotension following tocolysis with nifedipine.
Topics: Adolescent; Cesarean Section; Female; Fetal Membranes, Premature Rupture; Fluid Therapy; Gestational | 2014 |
Safety of Immediate-Release Nifedipine.
Topics: Aged; Arrhythmias, Cardiac; Calcium Channel Blockers; Drug Compounding; Female; Follow-Up Studies; H | 2016 |
Simultaneous posterior ischemic optic neuropathy, cerebral border zone infarction, and spinal cord infarction after correction of malignant hypertension.
Topics: Adult; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Brain; Brain Stem Infarctions; C | 2008 |
Hypotension due to the drug interaction of voriconazole with eplerenone and nifedipine.
Topics: Antifungal Agents; Antihypertensive Agents; Drug Interactions; Drug Therapy, Combination; Eplerenone | 2009 |
Hypotensive and vasorelaxant effects of citronellol, a monoterpene alcohol, in rats.
Topics: Acyclic Monoterpenes; Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, | 2010 |
Hypotension in normotensive pregnant women treated with nifedipine as a tocolytic drug.
Topics: Adolescent; Adult; Female; Humans; Hypotension; Middle Aged; Nifedipine; Obstetric Labor, Premature; | 2011 |
(-)-(9S)-9-(3-Bromo-4-fluorophenyl)-2,3,5,6,7,9-hexahydrothieno[3,2-b]quinolin-8(4H)-one 1,1-dioxide (A-278637), a novel ATP-sensitive potassium channel opener: hemodynamic comparison to ZD-6169, WAY-133537, and nifedipine in the anesthetized canine.
Topics: Adenosine Triphosphate; Amides; Animals; Benzophenones; Blood Pressure; Cyclic S-Oxides; Cyclobutane | 2004 |
Severe hypotension and fetal death due to tocolysis with nifedipine.
Topics: Adult; Female; Fetal Death; Humans; Hypotension; Nifedipine; Obstetric Labor, Premature; Pregnancy; | 2005 |
Severe hypotension and fetal death due to tocolysis with nifedipine.
Topics: Female; Humans; Hypotension; Nifedipine; Obstetric Labor, Premature; Pregnancy; Tocolysis; Tocolytic | 2005 |
Severe hypotension and fetal death due to tocolysis with nifedipine.
Topics: Female; Fetal Death; Humans; Hypotension; Nifedipine; Pregnancy; Pregnancy Complications, Cardiovasc | 2005 |
Severe hypotension and fetal death due to tocolysis with nifedipine.
Topics: Female; Fetal Death; Health Care Surveys; Humans; Hypotension; Nifedipine; Obstetric Labor, Prematur | 2005 |
Adverse interaction between nifedipine and beta-blockade.
Topics: Adrenergic beta-Antagonists; Drug Interactions; Drug Therapy, Combination; Humans; Hypotension; Nife | 1981 |
Acute hypotensive response to nifedipine added to prazosin in treatment of hypertension.
Topics: Adult; Drug Therapy, Combination; Humans; Hypertension; Hypotension; Male; Nifedipine; Prazosin; Qui | 1983 |
Lower extremity ischemia associated with use of military antishock trousers.
Topics: Blood Pressure; Gravity Suits; Humans; Hypotension; Ischemia; Leg; Male; Middle Aged; Nifedipine | 1984 |
Cerebral high energy phosphates after hypoxic-hypotension: effect of verapamil and nifedipine.
Topics: Adenosine Triphosphate; Animals; Brain; Cerebrovascular Circulation; Hypotension; Hypoxia, Brain; Ma | 1984 |
Hypotension induced changes in cerebral microflow and EEG and their pharmacological alterations.
Topics: Animals; Blood Pressure; Brain Ischemia; Cats; Cerebrovascular Circulation; Electroencephalography; | 1983 |
Adverse interaction between nifedipine and beta-blockade.
Topics: Drug Interactions; Humans; Hypotension; Male; Middle Aged; Myocardial Infarction; Nifedipine; Propra | 1981 |
Perioperative coronary arterial spasm: long-term follow-up.
Topics: Adult; Aged; Cardiac Catheterization; Cardiac Output, Low; Coronary Angiography; Coronary Artery Byp | 1982 |
Calcium ion blocking drugs.
Topics: Administration, Oral; Bradycardia; Calcium Channel Blockers; Diltiazem; Dizziness; Headache; Heart D | 1982 |
Calcium channel blockers: indications and limitations 1. Clinical pharmacology and use as antiarrhythmic agents.
Topics: Anti-Arrhythmia Agents; Biological Availability; Calcium; Calcium Channel Blockers; Cardiovascular D | 1982 |
Intraoperative use of nifedipine for hemodynamic collapse due to coronary artery spasm following myocardial revascularization.
Topics: Coronary Vasospasm; Heart Arrest; Heart Rate; Hemodynamics; Humans; Hypotension; Intraoperative Comp | 1982 |
Unpredictable response to nifedipine in severe cardiac failure.
Topics: Heart Failure; Hemodynamics; Humans; Hypotension; Male; Middle Aged; Nifedipine; Pyridines | 1980 |
Adverse interaction between nifedipine and beta-blockade.
Topics: Angina Pectoris; Atenolol; Drug Interactions; Drug Therapy, Combination; Humans; Hypertension; Hypot | 1980 |
Nifedipine and mortality. Grave defects in the dossier.
Topics: Angina Pectoris; Arrhythmias, Cardiac; Autonomic Nervous System; Calcium Channel Blockers; Coronary | 1995 |
Addition of pentoxifylline plus nifedipine to chemotherapy in patients with cisplatin-resistant cancers of the lung and other sites.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Drug Evaluation; Drug R | 1994 |
Severe hypotension and fetal distress following sublingual administration of nifedipine to a patient with severe pregnancy induced hypertension at 33 weeks.
Topics: Adult; Female; Fetal Distress; Humans; Hypertension; Hypotension; Nifedipine; Pregnancy; Pregnancy C | 1993 |
Precipitous hypotension after nifedipine in pheochromocytoma: report of 2 cases.
Topics: Adrenal Gland Neoplasms; Adult; Fatal Outcome; Female; Humans; Hypotension; Nifedipine; Pheochromocy | 1993 |
Hypertension and hypoparathyroidism--narrowed therapeutic safety with nifedipine.
Topics: Adult; Contraindications; Female; Humans; Hypertension; Hypocalcemia; Hypoparathyroidism; Hypotensio | 1993 |
Nifedipine overdose in a 70 year old man.
Topics: Aged; Bradycardia; Drug Overdose; Humans; Hypertension; Hypotension; Male; Nifedipine; Pulmonary Ede | 1993 |
Severe hypotension with enalapril.
Topics: Enalapril; Humans; Hypertension; Hypotension; Nifedipine | 1993 |
A one-year evaluation of calcium channel blocker overdoses: toxicity and treatment.
Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Atropine; Calcium; Calcium Channel Blockers; Child; C | 1993 |
Amelioration of nifedipine poisoning associated with glucagon therapy.
Topics: Adult; Calcium Chloride; Drug Therapy, Combination; Glucagon; Humans; Hypotension; Male; Nifedipine; | 1993 |
Reversal of acute theophylline toxicity by calcium channel blockers in dogs and rats.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Bronchodilator Agents; Calcium; Calcium Channel Block | 1996 |
Calcium channel blockers induce thymic apoptosis in vivo in rats.
Topics: Animals; Apoptosis; Calcium Channel Blockers; Chlorpromazine; Diltiazem; Dopamine Antagonists; Dose- | 1996 |
Effects of nilvadipine (a dihydropyridine-type calcium entry blocker) on cerebral blood flow in acute experimental brain ischemia in rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Brain Ischemia; Calcium Channel Blockers; Cerebrov | 1996 |
Vasodilators, aortic elasticity, and ventricular end-systolic stress in nonanesthetized unrestrained rats.
Topics: Animals; Aorta; Blood Pressure; Elasticity; Hydralazine; Hypotension; Male; Nifedipine; Nitroprussid | 1997 |
A moratorium should be placed on the use of short-acting nifedipine for hypertensive crises.
Topics: Calcium Channel Blockers; Child; Female; Humans; Hypertension; Hypotension; Nifedipine | 1998 |
Inhaled nitric oxide in primary pulmonary hypertension: a safe and effective agent for predicting response to nifedipine.
Topics: Administration, Inhalation; Administration, Oral; Calcium Channel Blockers; Female; Hemodynamics; Hu | 1998 |
Hypotension does not alter the antinociceptive effect of nifedipine.
Topics: Analgesics; Animals; Calcium Channel Blockers; Hypotension; Male; Nifedipine; Rats; Rats, Sprague-Da | 1998 |
The use of sublingual nifedipine: a continuing concern.
Topics: Administration, Sublingual; Anecdotes as Topic; Angina, Unstable; Antihypertensive Agents; Calcium C | 1999 |
Utilization of a glucagon infusion in the management of a massive nifedipine overdose.
Topics: Administration, Oral; Calcium Channel Blockers; Delayed-Action Preparations; Emergency Treatment; Ga | 2000 |
Fatal nifedipine ingestions in children.
Topics: Accidents, Home; Bradycardia; Calcium Channel Blockers; Fatal Outcome; Female; Humans; Hypotension; | 2000 |
Continuous calcium chloride infusion for massive nifedipine overdose.
Topics: Adult; Calcium; Calcium Channel Blockers; Calcium Chloride; Drug Overdose; Female; Humans; Hypotensi | 2001 |
Calcium channels contribute to the decrease in blood pressure of pregnant rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2002 |
Evaluation of the safety of short-acting nifedipine in children with hypertension.
Topics: Adolescent; Blood Pressure; Calcium Channel Blockers; Child; Child, Preschool; Dose-Response Relatio | 2002 |
Hypotensive effect of the methanolic extract of Mimusops elengi in normotensive rats.
Topics: Acute Disease; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Drug Syne | 1999 |
Severe hypotension with enalapril.
Topics: Administration, Oral; Administration, Sublingual; Drug Therapy, Combination; Enalapril; Humans; Hype | 1992 |
Nifedipine and hypotension.
Topics: Humans; Hypertension; Hypotension; Male; Middle Aged; Nifedipine | 1991 |
Hypotension decreases GABA levels in brainstem regions of the rat.
Topics: Alanine; Animals; Blood Pressure; Brain Stem; gamma-Aminobutyric Acid; Ganglionic Blockers; Glycine; | 1990 |
Efficacy of nifedipine to prevent systemic and renal vasoconstrictor effects of endothelin.
Topics: Angiotensin II; Animals; Blood Pressure; Endothelins; Endothelium, Vascular; Hypertension; Hypotensi | 1990 |
Calcium channel blocker toxicity.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arrhythmias, Cardiac; Child; Child, Preschool; Delaware; | 1990 |
Enhanced hypoxic pulmonary vasoconstriction in hypertension.
Topics: Adrenergic alpha-Antagonists; Calcium Channel Blockers; Humans; Hypotension; Hypoxia; Male; Middle A | 1989 |
Nifedipine-induced hypotension and mesenteric ischemia.
Topics: Adrenergic beta-Antagonists; Calcium Chloride; Drug Therapy, Combination; Hemodynamics; Humans; Hypo | 1989 |
A plea for noradrenaline.
Topics: Chlorpromazine; Humans; Hypotension; Male; Middle Aged; Nifedipine; Norepinephrine | 1989 |
Nifedipine inhibits cholecystokinin-induced gallbladder contraction.
Topics: Adult; Animals; Cholecystokinin; Female; Gallbladder; Guinea Pigs; Humans; Hypotension; Male; Muscle | 1989 |
Adverse effects of sublingual nifedipine in acute myocardial infarction.
Topics: Administration, Sublingual; Chest Pain; Heart Arrest; Humans; Hypotension; Male; Middle Aged; Myocar | 1989 |
Suppression of rat carotid lesion development by the calcium channel blocker PN 200-110.
Topics: Angioplasty, Balloon; Animals; Arteriosclerosis; Blood Platelets; Blood Pressure; Carotid Arteries; | 1986 |
Nifedipine enhances the vasodepressor and natriuretic effects of atrial natriuretic peptide.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Creatinine; Drug Synergism; Female; Hypotension; | 1988 |
Vasodilator therapy-induced pacemaker syndrome.
Topics: Humans; Hypotension; Male; Middle Aged; Nifedipine; Nitroglycerin; Pacemaker, Artificial; Syncope; S | 1987 |
Nifedipine, hypotension, and myocardial injury.
Topics: Administration, Sublingual; Aged; Female; Humans; Hypotension; Myocardial Infarction; Nifedipine | 1988 |
Symptomatic hypotension induced by nifedipine.
Topics: Drug Administration Schedule; Emergencies; Humans; Hypertension; Hypotension; Nifedipine | 1987 |
Nifedipine overdose.
Topics: Atropine; Bradycardia; Calcium Chloride; Diuretics; Electrocardiography; Gravity Suits; Humans; Hypo | 1986 |
Symptomatic hypotension induced by nifedipine in the acute treatment of severe hypertension.
Topics: Female; Humans; Hypertension; Hypotension; Male; Middle Aged; Nifedipine | 1987 |
Calcium-channel blockers in acute hypertension.
Topics: Acute Disease; Blood Pressure; Calcium Channel Blockers; Costs and Cost Analysis; Emergencies; Heart | 1985 |
Aggravation of myocardial ischaemia by nifedipine.
Topics: Coronary Disease; Female; Humans; Hypotension; Male; Middle Aged; Myocardial Infarction; Nifedipine; | 1985 |
Hypotension and sinus arrest with nifedipine in pulmonary hypertension.
Topics: Arrhythmia, Sinus; Female; Humans; Hypertension, Pulmonary; Hypotension; Middle Aged; Nifedipine | 1985 |
The lack of effect of nifedipine on failing skin flaps.
Topics: Animals; Hypotension; Microcirculation; Nifedipine; Skin; Surgical Flaps; Swine; Time Factors | 1985 |
Nifedipine-induced hypotension and myocardial ischemia in refractory angina pectoris.
Topics: Angina Pectoris; Humans; Hypotension; Nifedipine | 1985 |
Potentiation by nifedipine and diltiazem of the hypotensive response after contrast angiography.
Topics: Aged; Benzazepines; Calcium Channel Blockers; Contrast Media; Diatrizoate; Diatrizoate Meglumine; Di | 1985 |
Nifedipine dilates the pulmonary vasculature without producing symptomatic systemic hypotension in upright resting and exercising patients with pulmonary hypertension secondary to chronic obstructive pulmonary disease.
Topics: Adult; Blood Pressure; Female; Humans; Hypertension, Pulmonary; Hypotension; Lung Diseases, Obstruct | 1985 |
[Vasodilator therapy in chronic thromboembolic cor pulmonare. Description of a case with unfavorable hemodynamic effects].
Topics: Adult; Female; Heart Block; Humans; Hypertension, Pulmonary; Hypotension; Nifedipine; Pulmonary Embo | 1985 |