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nifedipine and Hypokalemia

nifedipine has been researched along with Hypokalemia in 10 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Hypokalemia: Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"Hypokalemia was found by normal urine excretion of potassium and normal intraerythrocyte potassium contents."5.28[Hypokalemia caused by nifedipine]. ( Angelova, I; Kundurdzhiev, A; Popiliev, I, 1990)
"Twelve patients with essential hypertension who were already on treatment with the long-acting calcium antagonist amlodipine (5 mg once daily) were entered into a double-blind, randomized crossover study of the addition of one month's treatment with either bendrofluazide (5 mg once daily) or matching placebo."5.07A double-blind crossover study of the effect of concomitant diuretic therapy in hypertensive patients treated with amlodipine. ( Buckley, MG; Cappuccio, FP; MacGregor, GA; Markandu, ND; Miller, MA; Sagnella, GA; Singer, DR, 1991)
"Primary hyperaldosteronism was detected in 1% of patients evaluated for secondary hypertension in a referral hospital in Southern India."1.29Primary hyperaldosteronism--diagnostic approach and management. ( Cherian, AM; Jesudason, SR; Kanagasabapathy, AS; Nair, A; Seshadri, MS, 1993)
"Treatment with spironolactone alone, or in combination with either intravenous dopamine or ibopamine orally, amiloride, enalapril, hydralazine or clonidine corrected serum potassium values but failed to normalize blood pressure and to correct plasma renin activity and plasma aldosterone."1.28A neonate with idiopathic hyperaldosteronism. ( Derkx, FH; Donckerwolcke, RA; Griffiven, AW; Schalekamp, MA; Vande Walle, JG; Veenhoven, RH; Wit, JM, 1991)
"Hypokalemia was found by normal urine excretion of potassium and normal intraerythrocyte potassium contents."1.28[Hypokalemia caused by nifedipine]. ( Angelova, I; Kundurdzhiev, A; Popiliev, I, 1990)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19903 (30.00)18.7374
1990's4 (40.00)18.2507
2000's2 (20.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Madhvani, RV1
Xie, Y1
Pantazis, A1
Garfinkel, A1
Qu, Z1
Weiss, JN1
Olcese, R1
Killeen, MJ1
Gurung, IS1
Thomas, G1
Stokoe, KS1
Grace, AA1
Huang, CL1
Struthers, AD1
Reid, JL1
Seshadri, MS1
Kanagasabapathy, AS1
Cherian, AM1
Nair, A1
Jesudason, SR1
Cely, CM1
Contreras, G1
Veenhoven, RH1
Vande Walle, JG1
Donckerwolcke, RA1
Wit, JM1
Griffiven, AW1
Derkx, FH1
Schalekamp, MA1
Cappuccio, FP1
Markandu, ND1
Singer, DR1
Buckley, MG1
Miller, MA1
Sagnella, GA1
MacGregor, GA1
Popiliev, I1
Angelova, I1
Kundurdzhiev, A1
van Gilst, WH1
Tijssen, JG1
van Es, GA1
Lubsen, J1
Tishler, M1
Armon, S1

Trials

1 trial available for nifedipine and Hypokalemia

ArticleYear
A double-blind crossover study of the effect of concomitant diuretic therapy in hypertensive patients treated with amlodipine.
    American journal of hypertension, 1991, Volume: 4, Issue:4 Pt 1

    Topics: Adult; Amlodipine; Bendroflumethiazide; Blood Pressure; Calcium Channel Blockers; Double-Blind Metho

1991

Other Studies

9 other studies available for nifedipine and Hypokalemia

ArticleYear
Shaping a new Ca²⁺ conductance to suppress early afterdepolarizations in cardiac myocytes.
    The Journal of physiology, 2011, Dec-15, Volume: 589, Issue:Pt 24

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Calcium; Calcium Channel Blockers; Hydrogen Peroxi

2011
Separation of early afterdepolarizations from arrhythmogenic substrate in the isolated perfused hypokalaemic murine heart through modifiers of calcium homeostasis.
    Acta physiologica (Oxford, England), 2007, Volume: 191, Issue:1

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Benzylamines; Calcium; Calcium Channel Blockers; C

2007
Nifedipine does not influence adrenaline induced hypokalaemia in man.
    British journal of clinical pharmacology, 1983, Volume: 16, Issue:3

    Topics: Adult; Drug Interactions; Epinephrine; Humans; Hypokalemia; Nifedipine

1983
Primary hyperaldosteronism--diagnostic approach and management.
    The Journal of the Association of Physicians of India, 1993, Volume: 41, Issue:5

    Topics: Adult; Female; Follow-Up Studies; Humans; Hyperaldosteronism; Hypokalemia; Male; Middle Aged; Nifedi

1993
Approach to the patient with hypertension, unexplained hypokalemia, and metabolic alkalosis.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2001, Volume: 37, Issue:3

    Topics: Adenoma; Adrenalectomy; Aldosterone; Alkalosis; Antihypertensive Agents; Diagnosis, Differential; Hu

2001
A neonate with idiopathic hyperaldosteronism.
    Pediatric nephrology (Berlin, Germany), 1991, Volume: 5, Issue:6

    Topics: Aldosterone; Calcium; Gastrointestinal Diseases; Humans; Hyperaldosteronism; Hypokalemia; Infant, Ne

1991
[Hypokalemia caused by nifedipine].
    Vutreshni bolesti, 1990, Volume: 29, Issue:3

    Topics: Aged; Clonidine; Drug Therapy, Combination; Female; Humans; Hypertension; Hypokalemia; Nifedipine

1990
Serum potassium values in relation to the use of diuretics in patients with unstable angina pectoris.
    European heart journal, 1988, Volume: 9, Issue:7

    Topics: Angina Pectoris; Angina, Unstable; Coronary Disease; Diuretics; Female; Humans; Hypokalemia; Male; M

1988
Nifedipine-induced hypokalemia.
    Drug intelligence & clinical pharmacy, 1986, Volume: 20, Issue:5

    Topics: Angina Pectoris; Humans; Hypokalemia; Male; Middle Aged; Nifedipine

1986