nifedipine has been researched along with Hypertrophy in 21 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Hypertrophy: General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amlodipine is one of the commonly prescribed antihypertensive drugs, and gingival hyperplasia is one overlooked side effect in patients taking amlodipine." | 8.12 | Amlodipine Induced Gum Hypertrophy: A Rare Case Report. ( Bohra, GK; Chhabra, V; Kumar, D; Midha, N; Reddy, SC, 2022) |
| "normalization of blood pressure and membrane oxidant status together with prevention of hypertrophy and normalization of the augmented expression of AM, IMD and their receptor components in NO-deficient cardiomyocytes by atenolol / nifedipine supports involvement of both pressure loading and ischemic insult in stimulating cardiomyocyte hypertrophy and induction of these counter-regulatory peptides and their receptor components." | 7.74 | Influence of atenolol and nifedipine on nitric-oxide deficient cardiomyocyte hypertrophy and expression of the cardio-endocrine peptide intermedin and its receptor components. ( Bell, D; Devine, AB; McDermott, BJ; Zhao, YY, 2008) |
| " Reduction of microalbuminuria at 27 weeks, compared to the vehicle group, was 37% and 52% in the enalapril- and nilvadipine-treated groups, respectively." | 7.72 | Nilvadipine attenuates mesangial expansion and glomerular hypertrophy in diabetic db/db mice, a model for type 2 diabetes. ( Imai, E; Moriyama, T; Oka, K; Ueda, H, 2004) |
| "We designed experiments to determine whether intermittent hypoxia would produce significant pathologic and physiologic changes in rats and whether pretreatment with a calcium channel blocker, nitrendipine, would reduce the pulmonary vascular remodeling and right ventricular hypertrophy caused by intermittent hypoxia." | 7.67 | Nitrendipine attenuates the pulmonary vascular remodeling and right ventricular hypertrophy caused by intermittent hypoxia in rats. ( Buescher, P; de la Monte, SM; Farrukh, I; Gottlieb, J; Gurtner, G; Hutchins, GM; Kennedy, TP; Lodato, R; Michael, JR; Rock, PC, 1986) |
| "Nifedipine (10 mg/kg) was administered intraperitoneally every day." | 5.29 | The effect of nifedipine on monocrotaline-induced pulmonary hypertension in rats. ( Harada, Y; Inoue, M; Mori, C; Tanaka, O; Watanabe, K, 1993) |
| "Amlodipine is one of the commonly prescribed antihypertensive drugs, and gingival hyperplasia is one overlooked side effect in patients taking amlodipine." | 4.12 | Amlodipine Induced Gum Hypertrophy: A Rare Case Report. ( Bohra, GK; Chhabra, V; Kumar, D; Midha, N; Reddy, SC, 2022) |
| "normalization of blood pressure and membrane oxidant status together with prevention of hypertrophy and normalization of the augmented expression of AM, IMD and their receptor components in NO-deficient cardiomyocytes by atenolol / nifedipine supports involvement of both pressure loading and ischemic insult in stimulating cardiomyocyte hypertrophy and induction of these counter-regulatory peptides and their receptor components." | 3.74 | Influence of atenolol and nifedipine on nitric-oxide deficient cardiomyocyte hypertrophy and expression of the cardio-endocrine peptide intermedin and its receptor components. ( Bell, D; Devine, AB; McDermott, BJ; Zhao, YY, 2008) |
| "1% nitroglycerin on demand; 3: internal anal sphincterotomy if hypertrophy of the internal anal sphincter was demonstrated by anal ultrasonography and no improvement was confirmed with the previous steps of treatment)." | 3.73 | Sequential treatment for proctalgia fugax. Mid-term follow-up. ( Aguilella Diago, V; Elía Guedea, M; Gracia Solanas, JA; Martínez Díez, M; Ramírez Rodríguez, JM, 2005) |
| " Reduction of microalbuminuria at 27 weeks, compared to the vehicle group, was 37% and 52% in the enalapril- and nilvadipine-treated groups, respectively." | 3.72 | Nilvadipine attenuates mesangial expansion and glomerular hypertrophy in diabetic db/db mice, a model for type 2 diabetes. ( Imai, E; Moriyama, T; Oka, K; Ueda, H, 2004) |
| " After treatment with a sustained release formulation of the calcium antagonist, nifedipine, their blood pressure returned to normal, anal tone was reduced, and the frequency and intensity of anal pain was suppressed." | 3.69 | Hereditary proctalgia fugax and constipation: report of a second family. ( Celik, AF; Donnelly, TC; Katsinelos, P; Khan, MI; Read, NW, 1995) |
| " Myosin HC synthesis also appeared to be independently regulated during cardiomyocyte atrophy induced by the calcium channel blocker nifedipine." | 3.69 | Myosin heavy chain synthesis is independently regulated in hypertrophy and atrophy of isolated adult cardiac myocytes. ( Andersen, LC; Clark, WA; LaPres, JJ; Rudnick, SJ, 1994) |
| "We designed experiments to determine whether intermittent hypoxia would produce significant pathologic and physiologic changes in rats and whether pretreatment with a calcium channel blocker, nitrendipine, would reduce the pulmonary vascular remodeling and right ventricular hypertrophy caused by intermittent hypoxia." | 3.67 | Nitrendipine attenuates the pulmonary vascular remodeling and right ventricular hypertrophy caused by intermittent hypoxia in rats. ( Buescher, P; de la Monte, SM; Farrukh, I; Gottlieb, J; Gurtner, G; Hutchins, GM; Kennedy, TP; Lodato, R; Michael, JR; Rock, PC, 1986) |
| "A significant reactive gliosis was observed within 2 days of cord lesion in untreated crush or vehicle-treated, crush control animals as evidenced by increased GFAP-IR and hypertrophy of astrocytes." | 1.30 | Calcium influx and activation of calpain I mediate acute reactive gliosis in injured spinal cord. ( Barrett, C; Du, S; Kim, YC; Klepper, S; Lee, EB; Markelonis, GJ; Oh, TH; Park, CW; Rhim, HW; Rubin, A, 1999) |
| "Nifedipine (10 mg/kg) was administered intraperitoneally every day." | 1.29 | The effect of nifedipine on monocrotaline-induced pulmonary hypertension in rats. ( Harada, Y; Inoue, M; Mori, C; Tanaka, O; Watanabe, K, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.76) | 18.7374 |
| 1990's | 11 (52.38) | 18.2507 |
| 2000's | 7 (33.33) | 29.6817 |
| 2010's | 1 (4.76) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Reddy, SC | 1 |
| Midha, N | 1 |
| Chhabra, V | 1 |
| Kumar, D | 1 |
| Bohra, GK | 1 |
| Ishiguro, K | 1 |
| Hayashi, K | 1 |
| Sasamura, H | 1 |
| Sakamaki, Y | 1 |
| Itoh, H | 1 |
| Marçal, DM | 1 |
| Rizzi, E | 1 |
| Martins-Oliveira, A | 1 |
| Ceron, CS | 1 |
| Guimaraes, DA | 1 |
| Gerlach, RF | 1 |
| Tanus-Santos, JE | 1 |
| Bito, V | 1 |
| Heinzel, FR | 1 |
| Weidemann, F | 1 |
| Dommke, C | 1 |
| van der Velden, J | 1 |
| Verbeken, E | 1 |
| Claus, P | 1 |
| Bijnens, B | 1 |
| De Scheerder, I | 1 |
| Stienen, GJ | 1 |
| Sutherland, GR | 1 |
| Sipido, KR | 1 |
| Moriyama, T | 1 |
| Oka, K | 1 |
| Ueda, H | 1 |
| Imai, E | 1 |
| de la Portilla, F | 1 |
| Borrero, JJ | 1 |
| Rafel, E | 1 |
| Gracia Solanas, JA | 1 |
| Ramírez Rodríguez, JM | 1 |
| Elía Guedea, M | 1 |
| Aguilella Diago, V | 1 |
| Martínez Díez, M | 1 |
| Arner, A | 1 |
| Sjuve Scott, R | 1 |
| Haase, H | 1 |
| Morano, I | 1 |
| Uvelius, B | 1 |
| Bell, D | 1 |
| Zhao, YY | 1 |
| Devine, AB | 1 |
| McDermott, BJ | 1 |
| Celik, AF | 1 |
| Katsinelos, P | 1 |
| Read, NW | 1 |
| Khan, MI | 1 |
| Donnelly, TC | 1 |
| Clark, WA | 1 |
| Rudnick, SJ | 1 |
| Andersen, LC | 1 |
| LaPres, JJ | 1 |
| Inoue, M | 1 |
| Harada, Y | 1 |
| Watanabe, K | 1 |
| Mori, C | 1 |
| Tanaka, O | 1 |
| Johnson, PL | 1 |
| Bhattacharya, SK | 1 |
| Dworkin, LD | 1 |
| Benstein, JA | 1 |
| Parker, M | 1 |
| Tolbert, E | 1 |
| Feiner, HD | 1 |
| Creed, KE | 1 |
| Malmgren, A | 1 |
| Schiffrin, EL | 1 |
| Deng, LY | 1 |
| Peiró, C | 1 |
| Llergo, JL | 1 |
| Angulo, J | 1 |
| López-Novoa, JM | 1 |
| Rodríguez-López, A | 1 |
| Rodríguez-Mañas, L | 1 |
| Sánchez-Ferrer, CF | 1 |
| King, JA | 1 |
| Huddart, H | 1 |
| Staff, WG | 1 |
| Du, S | 1 |
| Rubin, A | 1 |
| Klepper, S | 1 |
| Barrett, C | 1 |
| Kim, YC | 1 |
| Rhim, HW | 1 |
| Lee, EB | 1 |
| Park, CW | 1 |
| Markelonis, GJ | 1 |
| Oh, TH | 1 |
| Murphy, RJ | 1 |
| Béliveau, L | 1 |
| Gardiner, PF | 1 |
| Calderone, A | 1 |
| Michael, JR | 1 |
| Kennedy, TP | 1 |
| Buescher, P | 1 |
| Farrukh, I | 1 |
| Lodato, R | 1 |
| Rock, PC | 1 |
| Gottlieb, J | 1 |
| Gurtner, G | 1 |
| de la Monte, SM | 1 |
| Hutchins, GM | 1 |
1 trial available for nifedipine and Hypertrophy
| Article | Year |
|---|---|
Structure and function of resistance arteries of hypertensive patients treated with a beta-blocker or a calcium channel antagonist.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Arteries; Atenolol; Calcium Channel Blockers; Female; Huma | 1996 |
20 other studies available for nifedipine and Hypertrophy
| Article | Year |
|---|---|
Amlodipine Induced Gum Hypertrophy: A Rare Case Report.
Topics: Aged; Amlodipine; Calcium Channel Blockers; Gingival Hyperplasia; Gingival Overgrowth; Humans; Hyper | 2022 |
"Pulse" treatment with high-dose angiotensin blocker reverses renal arteriolar hypertrophy and regresses hypertension.
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Anim | 2009 |
Comparative study on antioxidant effects and vascular matrix metalloproteinase-2 downregulation by dihydropyridines in renovascular hypertension.
Topics: Amlodipine; Animals; Antioxidants; Aorta, Thoracic; Blood Pressure; Body Weight; Calcium Channel Blo | 2011 |
Cellular mechanisms of contractile dysfunction in hibernating myocardium.
Topics: Actin Cytoskeleton; Action Potentials; Animals; Calcium Channels, L-Type; Calcium Signaling; Cell Si | 2004 |
Nilvadipine attenuates mesangial expansion and glomerular hypertrophy in diabetic db/db mice, a model for type 2 diabetes.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Blood Pressure; Body | 2004 |
Hereditary vacuolar internal anal sphincter myopathy causing proctalgia fugax and constipation: a new case contribution.
Topics: Aged; Anus Diseases; Calcium Channel Blockers; Constipation; Female; Humans; Hypertrophy; Muscle, Sm | 2005 |
Sequential treatment for proctalgia fugax. Mid-term follow-up.
Topics: Acute Disease; Adult; Anal Canal; Anti-Anxiety Agents; Anus Diseases; Baths; Benzodiazepines; Endoso | 2005 |
Intracellular calcium in hypertrophic smooth muscle from rat urinary bladder.
Topics: Animals; Antibodies; Calcium; Calcium Channels; Female; Fura-2; Hypertrophy; Muscle, Smooth; Nifedip | 2007 |
Influence of atenolol and nifedipine on nitric-oxide deficient cardiomyocyte hypertrophy and expression of the cardio-endocrine peptide intermedin and its receptor components.
Topics: Adrenomedullin; Animals; Atenolol; Atrial Natriuretic Factor; Blood Pressure; Endothelin-1; Gene Exp | 2008 |
Hereditary proctalgia fugax and constipation: report of a second family.
Topics: Adult; Aged; Anal Canal; Constipation; Family; Female; Humans; Hypertension; Hypertrophy; Male; Midd | 1995 |
Myosin heavy chain synthesis is independently regulated in hypertrophy and atrophy of isolated adult cardiac myocytes.
Topics: Actins; Animals; Atrophy; Calcium Channels; Cats; Cells, Cultured; Desmin; Gene Expression Regulatio | 1994 |
The effect of nifedipine on monocrotaline-induced pulmonary hypertension in rats.
Topics: Acute Disease; Animals; Body Weight; Disease Models, Animal; Drug Evaluation, Preclinical; Heart Ven | 1993 |
Regulation of membrane-mediated chronic muscle degeneration in dystrophic hamsters by calcium-channel blockers: diltiazem, nifedipine and verapamil.
Topics: Animals; Body Weight; Calcium; Calcium Channel Blockers; Cardiomegaly; Creatine Kinase; Cricetinae; | 1993 |
Calcium antagonists and converting enzyme inhibitors reduce renal injury by different mechanisms.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Enalapril; Glomeruloscl | 1993 |
The effect of cromakalim on the electrical properties of and [86Rb+] efflux from normal and hypertrophied rat bladder.
Topics: Action Potentials; Animals; Benzopyrans; Calcium Channel Blockers; Cromakalim; Electrophysiology; Fe | 1993 |
Effects of captopril, losartan, and nifedipine on cell hypertrophy of cultured vascular smooth muscle from hypertensive Ren-2 transgenic rats.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Biphenyl Compounds; Captopril; Cells, Cultur | 1997 |
Effect of choline ester analogues, noradrenaline and nifedipine on normal and hypertrophied human urinary bladder detrusor muscle.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Bethanechol; Calcium; Calcium Channel Blockers; Carbachol; | 1998 |
Calcium influx and activation of calpain I mediate acute reactive gliosis in injured spinal cord.
Topics: Acute Disease; Animals; Astrocytes; Calcium; Calcium Channel Blockers; Calpain; Enzyme Activation; G | 1999 |
Nifedipine does not impede clenbuterol-stimulated muscle hypertrophy.
Topics: Adrenergic beta-Agonists; Animals; Blood Pressure; Body Weight; Calcium; Calcium Channels; Calcium C | 1999 |
Nitrendipine attenuates the pulmonary vascular remodeling and right ventricular hypertrophy caused by intermittent hypoxia in rats.
Topics: Animals; Cardiomegaly; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy; Hypoxia; Male; Muscle | 1986 |