Page last updated: 2024-11-01

nifedipine and Hypertrophy, Left Ventricular

nifedipine has been researched along with Hypertrophy, Left Ventricular in 60 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Hypertrophy, Left Ventricular: Enlargement of the LEFT VENTRICLE of the heart. This increase in ventricular mass is attributed to sustained abnormal pressure or volume loads and is a contributor to cardiovascular morbidity and mortality.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to evaluate the effects of lercanidipine or barnidipine on echocardiographic parameters, in hypertensive, type 2 diabetics with left ventricular hypertrophy."9.20Barnidipine or Lercanidipine on Echocardiographic Parameters in Hypertensive, Type 2 Diabetics with Left Ventricular Hypertrophy: A Randomized Clinical Trial. ( D'Angelo, A; Derosa, G; Franzetti, I; Maffioli, P; Mugellini, A; Pesce, RM; Querci, F, 2015)
"We treated with nifedipine or lisinopril 38 essential hypertensive patients with left ventricular hypertrophy."9.08Lisinopril reverses left ventricular hypertrophy through improved aortic compliance. ( Shimamoto, H; Shimamoto, Y, 1996)
" This study assessed the efficacy and safety of nifedipine GITS (oral release osmotic system) as monotherapy, in addition to the effects on left ventricular hypertrophy, after a long term follow-up (one year)."9.08[Nifedipine in the treatment of moderate and severe arterial hypertension. Long-term effect on arterial pressure and on the left ventricle]. ( Arocha, I; Arreaza, MR; Bustillo, N; Corral, JL; García, P; López, NC; Perozo, M, 1997)
"To assess the effect of 1-year treatment with rilmenidine, an oxazoline compound that exerts its antihypertensive effects through binding to imidazoline receptors in the brainstem, on left ventricular hypertrophy (LVH) secondary to essential, mild-to-moderate hypertension [supine diastolic blood pressure (DBP)95-115 mmHg]."9.08Regression of left ventricular hypertrophy in hypertensive patients after 1 year of treatment with rilmenidine: a double-blind, randomized, controlled (versus nifedipine) study. ( Balazovjech, I; Dubai, G; Dvorak, I; Januszewicz, W; Krupa-Wojciechowska, B; Kubasik, A; Kuch-Wocial, A; Polak, G; Sadowski, Z; Simon, K; Stejfa, M; Szwed, H, 1998)
"5 mg/day) on regression of left ventricular hypertrophy (LVH), an independent predictor of poor prognosis in hypertension, was compared by echocardiography to that of nifedipine (NFD, 40 mg/day), enalapril (ENL, 20 mg/day), atenolol (ATL, 100 mg/day), and hydrochlorothiazide (HCTZ, 25 mg/day) in four parallel double-blind studies in 151 hypertensive patients with a diastolic blood pressure between 95 and 120 mm Hg and a raised left ventricular mass index (LVMI) (mg/m2) (Devereux)."9.07Indapamide reduces hypertensive left ventricular hypertrophy: an international multicenter study. ( Amabile, G; Bory, M; De Luca, N; Denis, B; Imbs, JL; Lahiri, A; Marchegiano, R; Raftery, EB; Senior, R; Zannad, F, 1993)
"We investigated the regression of left ventricular (LV) hypertrophy with long-term treatment of nifedipine in patients with systemic hypertension."7.69Regression of left ventricular hypertrophy with long-term treatment of nifedipine in systemic hypertension. ( Maeda, M; Nakano, T; Oonishi, T; Teramura, S; Yamakado, T, 1994)
" This study evaluated the influence of aging, superimposed chronic hypertension on aging, and treatment with nifedipine on cardiac myosin isozyme proportions."7.68Alterations in cardiac myosin isozymes associated with aging and chronic hypertension: their modulation with nifedipine. ( Blomquist, TM; Minser, R; Pathak, D; Raizada, V; Woodfin, B, 1993)
"More enalapril-treated than nifedipine-treated patients required supplemental treatment with hydrochlorothiazide (59% versus 34%, P<0."6.70Effects of once-daily angiotensin-converting enzyme inhibition and calcium channel blockade-based antihypertensive treatment regimens on left ventricular hypertrophy and diastolic filling in hypertension: the prospective randomized enalapril study evaluat ( Bella, JN; Dahlöf, B; De Quattro, V; de Simone, G; Devereux, RB; Hahn, RT; Palmieri, V; Sharpe, N; Walker, JF, 2001)
"Marked left ventricular hypertrophy and fibrosis were apparent and the ratio of collagen type I to type III mRNA levels and the activity of matrix metalloproteinase (MMP)-2 and its mRNA expression in the myocardium were increased in Vehicle at 19 weeks in comparison with Control."5.35Long-term administration of nifedipine attenuates cardiac remodeling and diastolic heart failure in hypertensive rats. ( Cheng, XW; Izawa, H; Kuzuya, M; Miyachi, M; Murohara, T; Nagata, K; Naruse, K; Nishizawa, T; Noda, A; Obata, K; Okumura, K; Saka, M; Yamada, T; Yokota, M, 2009)
"The aim of this study was to evaluate the effects of lercanidipine or barnidipine on echocardiographic parameters, in hypertensive, type 2 diabetics with left ventricular hypertrophy."5.20Barnidipine or Lercanidipine on Echocardiographic Parameters in Hypertensive, Type 2 Diabetics with Left Ventricular Hypertrophy: A Randomized Clinical Trial. ( D'Angelo, A; Derosa, G; Franzetti, I; Maffioli, P; Mugellini, A; Pesce, RM; Querci, F, 2015)
" Patients with essential hypertension were randomly assigned to receive either amlodipine, cilnidipine or nifedipine CR (which does not block N-type calcium channels) for 6 months."5.10Effects of calcium channel antagonists on left ventricular hypertrophy and diastolic function in patients with essential hypertension. ( Shigematsu, M; Takami, T, 2003)
"We treated with nifedipine or lisinopril 38 essential hypertensive patients with left ventricular hypertrophy."5.08Lisinopril reverses left ventricular hypertrophy through improved aortic compliance. ( Shimamoto, H; Shimamoto, Y, 1996)
" This study assessed the efficacy and safety of nifedipine GITS (oral release osmotic system) as monotherapy, in addition to the effects on left ventricular hypertrophy, after a long term follow-up (one year)."5.08[Nifedipine in the treatment of moderate and severe arterial hypertension. Long-term effect on arterial pressure and on the left ventricle]. ( Arocha, I; Arreaza, MR; Bustillo, N; Corral, JL; García, P; López, NC; Perozo, M, 1997)
"This study compared the effects of 1 year of monotherapy with a calcium-channel antagonist (nilvadipine; NIL), an angiotensin-converting enzyme (ACE) inhibitor (temocapril; TEM), or a new vasodilator (cadralazine; CAD) on left ventricular (LV) hypertrophy in essential hypertension."5.08The effects of long-term treatment on left ventricular hypertrophy in patients with essential hypertension: relation to changes in neurohumoral factors. ( Inoue, H; Oh-hashi, S; Takata, M; Tomita, S; Ueno, H; Yasumoto, K, 1997)
"To assess the effect of 1-year treatment with rilmenidine, an oxazoline compound that exerts its antihypertensive effects through binding to imidazoline receptors in the brainstem, on left ventricular hypertrophy (LVH) secondary to essential, mild-to-moderate hypertension [supine diastolic blood pressure (DBP)95-115 mmHg]."5.08Regression of left ventricular hypertrophy in hypertensive patients after 1 year of treatment with rilmenidine: a double-blind, randomized, controlled (versus nifedipine) study. ( Balazovjech, I; Dubai, G; Dvorak, I; Januszewicz, W; Krupa-Wojciechowska, B; Kubasik, A; Kuch-Wocial, A; Polak, G; Sadowski, Z; Simon, K; Stejfa, M; Szwed, H, 1998)
"The aim of this study was to evaluate the effect of the calcium antagonist Nifedipine GITS in a double-blind, randomized comparison with the diuretic hydrochlorothiazide (HCTZ) on reduction of left ventricular (LV) mass and minimal vascular resistance in a group of essential hypertensives with left ventricular hypertrophy (LVH)."5.08Reduction of cardiovascular structural changes by nifedipine GITS in essential hypertensive patients. ( Agabiti-Rosei, E; Corbellini, C; Monteduro, C; Muiesan, ML; Rizzoni, D; Salvetti, M; Zulli, R, 1998)
"5 mg/day) on regression of left ventricular hypertrophy (LVH), an independent predictor of poor prognosis in hypertension, was compared by echocardiography to that of nifedipine (NFD, 40 mg/day), enalapril (ENL, 20 mg/day), atenolol (ATL, 100 mg/day), and hydrochlorothiazide (HCTZ, 25 mg/day) in four parallel double-blind studies in 151 hypertensive patients with a diastolic blood pressure between 95 and 120 mm Hg and a raised left ventricular mass index (LVMI) (mg/m2) (Devereux)."5.07Indapamide reduces hypertensive left ventricular hypertrophy: an international multicenter study. ( Amabile, G; Bory, M; De Luca, N; Denis, B; Imbs, JL; Lahiri, A; Marchegiano, R; Raftery, EB; Senior, R; Zannad, F, 1993)
" We therefore investigated the effects of diltiazem on cardiac gene expression in normotensive and hypertensive rats with left ventricular hypertrophy and compared the results with our previous findings on verapamil and nifedipine."3.83Gene expression profiling of calcium-channel antagonists in the heart of hypertensive and normotensive rats reveals class specific effects. ( Borlak, J; Zwadlo, C, 2016)
"Losartan reduced significantly the systolic blood pressure as well as the aorta and left ventricular hypertrophy."3.74Beneficial effects of the combination of nifedipine and losartan in hypertensive Dahl salt-sensitive rats. ( Tinel, H, 2007)
" We treated 16-week-old rats having established LVH and myocardial fibrosis due to 8-week renovascular hypertension (RHT) with either 6 mg/kg/day zofenopril (ZOF), 30 mg/kg/day nifedipine (NIF) or 40 mg/kg/day labetalol (LAB) for 12 weeks."3.70Regression of myocardial fibrosis in hypertensive heart disease: diverse effects of various antihypertensive drugs. ( Brilla, CG, 2000)
"Effects of m-nifedipine (m-Nif) on the affinity and density of dihydropyridine (DHP) binding sites in the cell membranes of kidney and lung were investigated using the LVH (left ventricular hypertrophy) induced by Goldblatt (2k-1c) renovascular hypertension in elderly rats."3.69[Effects of m-nifedipine on dihydropyridine binding sites in the cell membranes of kidney and lung from left ventricular hypertrophied elderly rats]. ( Rao, MR; Xi, T; Xu, Y, 1995)
"We investigated the regression of left ventricular (LV) hypertrophy with long-term treatment of nifedipine in patients with systemic hypertension."3.69Regression of left ventricular hypertrophy with long-term treatment of nifedipine in systemic hypertension. ( Maeda, M; Nakano, T; Oonishi, T; Teramura, S; Yamakado, T, 1994)
"To evaluate the effect of acute blood pressure (BP) changes on the myocardial perfusion in hypertensives, 10 patients with and 10 patients without left ventricular hypertrophy (LVH) were examined with 99TCm-Sestamibi scintigraphy at rest and after acute pharmacological BP reduction using nifedipine and captopril."3.69Blood pressure and myocardial perfusion in hypertensive patients with and without left ventricular hypertrophy. ( Berglund, G; Boström, PA; Diemer, H; Lilja, B; Mansour, P; Mattiasson, I; Nehoum, A, 1995)
" This study evaluated the influence of aging, superimposed chronic hypertension on aging, and treatment with nifedipine on cardiac myosin isozyme proportions."3.68Alterations in cardiac myosin isozymes associated with aging and chronic hypertension: their modulation with nifedipine. ( Blomquist, TM; Minser, R; Pathak, D; Raizada, V; Woodfin, B, 1993)
"On 24 h ambulatory BP monitoring, nifedipine-GITS caused a consistent decrease in BP throughout the 24 h dosing interval, whereas felodipine-ER caused a more marked fall in BP during the day, and enalapril's effects diminished during the night and had disappeared by the morning."2.70Differential effects of once-daily antihypertensive drugs on blood pressure, left ventricular mass and sympathetic activity: Nifedipine-GITS versus felodipine-ER versus enalapril. ( Joyner, CD; Leenen, FH; Myers, MG; Toal, CB, 2002)
"More enalapril-treated than nifedipine-treated patients required supplemental treatment with hydrochlorothiazide (59% versus 34%, P<0."2.70Effects of once-daily angiotensin-converting enzyme inhibition and calcium channel blockade-based antihypertensive treatment regimens on left ventricular hypertrophy and diastolic filling in hypertension: the prospective randomized enalapril study evaluat ( Bella, JN; Dahlöf, B; De Quattro, V; de Simone, G; Devereux, RB; Hahn, RT; Palmieri, V; Sharpe, N; Walker, JF, 2001)
" At the end of the dosing interval, felodipine lowered office DBP (mm Hg) by -18 +/- 12/14 +/- 1 compared to -14 +/- 2/11 +/- 1 for nifedipine (P < or = ."2.68Differential effects of felodipine and nifedipine on 24-h blood pressure and left ventricular mass. ( Leenen, FH; Myers, MG; Tanner, J, 1995)
"Chronic left ventricular hypertrophy (LVH) is associated with depressed contractile performance, abnormal compliance of the chamber, and ultimately, the development of a left ventricular failure."2.68[The effect of hypotensive drugs on left ventricular mass and diastolic function]. ( Haczyński, J; Jołda-Mydłowska, B; Spring, A; Witkowska, M, 1995)
"Hypertension affects about 5% of western populations and in the majority of cases it is of unknown aetiology."2.41Experimental studies on myocardial stretch and ventricular arrhythmia in hypertrophied and non-hypertrophied hearts. ( Dalton, GR; Evans, SJ; Levi, AJ, 2000)
"Marked left ventricular hypertrophy and fibrosis were apparent and the ratio of collagen type I to type III mRNA levels and the activity of matrix metalloproteinase (MMP)-2 and its mRNA expression in the myocardium were increased in Vehicle at 19 weeks in comparison with Control."1.35Long-term administration of nifedipine attenuates cardiac remodeling and diastolic heart failure in hypertensive rats. ( Cheng, XW; Izawa, H; Kuzuya, M; Miyachi, M; Murohara, T; Nagata, K; Naruse, K; Nishizawa, T; Noda, A; Obata, K; Okumura, K; Saka, M; Yamada, T; Yokota, M, 2009)
"Nifedipine-treated animals displayed hemodynamics, LV dilatation, hypertrophy, and loss of function similar to those of the untreated group."1.35Comparative study of vasodilators in an animal model of chronic volume overload caused by severe aortic regurgitation. ( Arsenault, M; Beaudoin, J; Champetier, S; Couet, J; Lachance, D; Plante, E; Roussel, E, 2009)
"Renovascular hypertension was produced by clipping the left renal artery in 20-month-old rats."1.29Effects of menidipine on dihydropyridines binding sites in cardiac and cerebral membranes from old rats with left ventricular hypertrophy. ( Rao, MR; Xi, T, 1996)

Research

Studies (60)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's34 (56.67)18.2507
2000's22 (36.67)29.6817
2010's4 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zimmer, J1
Hawlitschek, C1
Rabald, S1
Hagendorff, A1
Zimmer, HG1
Rassler, B1
Derosa, G1
Mugellini, A1
Querci, F1
Franzetti, I1
Pesce, RM1
D'Angelo, A1
Maffioli, P1
Zwadlo, C1
Borlak, J1
Yamada, T1
Nagata, K1
Cheng, XW1
Obata, K1
Saka, M1
Miyachi, M1
Naruse, K1
Nishizawa, T1
Noda, A1
Izawa, H1
Kuzuya, M1
Okumura, K1
Murohara, T1
Yokota, M1
Ye, P1
Wu, CE1
Sheng, L1
Li, H1
Plante, E2
Lachance, D1
Beaudoin, J1
Champetier, S1
Roussel, E1
Arsenault, M2
Couet, J2
Bozbaş, SS1
Bozbaş, H1
Atar, A1
Ulubay, G1
Oner Eyüboğlu, F1
Leenen, FH2
Myers, MG2
Joyner, CD1
Toal, CB1
Tse, HF1
Cheung, BM1
Ng, W1
Chan, JK1
Devereux, RB4
Lau, CP1
Gaudreau, M1
Dumas, MP1
Drolet, MC1
Terpstra, WF1
May, JF1
Smit, AJ1
de Graeff, PA1
Crijns, HJ1
Takami, T1
Shigematsu, M1
Boydak, B1
Nalbantgil, S1
Yilmaz, H1
Zoghi, M1
Ozerkan, F1
Nalbantgil, I1
Onder, R1
Higashikuni, Y1
Sata, M1
Nagai, R1
Iskenderov, BG2
Burmistrova, LF2
Vakina, TN1
Lokhina, TV2
Bogdanova, SR1
Afshinnia, F1
Xie, HH1
Shen, FM1
Zhang, XF1
Jiang, YY1
Su, DF1
Tinel, H1
Berenshteĭn, NV1
Senior, R1
Imbs, JL1
Bory, M1
Amabile, G1
Denis, B1
Zannad, F1
De Luca, N1
Marchegiano, R1
Lahiri, A1
Raftery, EB1
Tanner, J1
Li, QP1
Rao, MR8
Xu, Y2
Xi, T5
Phillips, RA2
Ghali, JK1
Kirpizidis, HG1
Papazachariou, GS1
Yamakado, T1
Teramura, S1
Oonishi, T1
Maeda, M1
Nakano, T1
Yang, JR1
Wu, DM1
Habib, GB1
Mann, DL1
Zoghbi, WA1
Nishimura, H2
Kubota, J1
Okabe, M2
Ueyama, M1
Oka, T1
Kawamura, K2
Savchenko, AP1
Smirnov, AA1
Bekzhigitov, SB1
Abugov, SA1
Shapkina, LS1
Arabidze, GG1
Raizada, V1
Pathak, D1
Blomquist, TM1
Minser, R1
Woodfin, B1
Amici, E1
Patruno, N1
Natale, E1
Marsocci, A1
Gambelli, G1
Sau, F1
Seguro, C1
Lai, C1
Onnis, E1
Orani, E1
Soro, A1
Leo, MR1
Cherchi, A1
Spring, A1
Haczyński, J1
Jołda-Mydłowska, B1
Witkowska, M1
Dahlof, B2
Levy, D1
Pfeffer, MA1
Boström, PA1
Mansour, P1
Diemer, H1
Mattiasson, I1
Nehoum, A1
Lilja, B1
Berglund, G1
Shimamoto, H1
Shimamoto, Y1
Handa, S1
Hamada, M1
Ura, M1
Yoshida, S1
Nishio, I1
López, NC1
Corral, JL1
Perozo, M1
García, P1
Bustillo, N1
Arreaza, MR1
Arocha, I1
Ueno, H1
Takata, M1
Tomita, S1
Oh-hashi, S1
Yasumoto, K1
Inoue, H1
Donohue, TJ1
Dworkin, LD1
Ma, J1
Lango, MN1
Catanese, VM1
Kimpara, T1
Hayashi, T1
Imamura, K1
Chang, KC1
Cherng, WJ1
Sadowski, Z1
Szwed, H1
Kuch-Wocial, A1
Kubasik, A1
Januszewicz, W1
Krupa-Wojciechowska, B1
Polak, G1
Stejfa, M1
Dvorak, I1
Balazovjech, I1
Dubai, G1
Simon, K1
Agabiti-Rosei, E1
Zulli, R1
Muiesan, ML1
Salvetti, M1
Rizzoni, D1
Corbellini, C1
Monteduro, C1
Wei, AY1
Li, YQ1
Chen, JF1
Liu, M1
Ji, Y1
Brilla, CG1
Evans, SJ1
Dalton, GR1
Levi, AJ1
Schussheim, AE1
Diamond, JA1
Sareli, P2
Radevski, IV1
Valtchanova, ZP1
Libhaber, E2
Candy, GP1
Den Hond, E1
Libhaber, C1
Skudicky, D2
Wang, JG2
Staessen, JA2
Palmieri, V2
Sharpe, N1
De Quattro, V1
Bella, JN1
de Simone, G1
Walker, JF1
Hahn, RT1
Candy, G1
Radevski, I1
Valtchanova, Z1
Tshele, E1
Thijs, L1
Gosse, P1
Roudaut, R1
Dallocchio, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of Some Emerging Biomarkers of Cardiovascular Risk Stratification in Hypertensive Patients: a 5-years Follow-up[NCT02064218]0 participants Observational2007-11-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for nifedipine and Hypertrophy, Left Ventricular

ArticleYear
Etiology, pathophysiology, and treatment of left ventricular hypertrophy: focus on severe hypertension.
    Journal of cardiovascular pharmacology, 1993, Volume: 21 Suppl 2

    Topics: Administration, Oral; Blood Pressure; Delayed-Action Preparations; Drug Delivery Systems; Female; Hu

1993
Experimental studies on myocardial stretch and ventricular arrhythmia in hypertrophied and non-hypertrophied hearts.
    Journal of cardiovascular risk, 2000, Volume: 7, Issue:3

    Topics: Animals; Arrhythmias, Cardiac; Calcium; Calcium Channel Blockers; Cardiotonic Agents; Death, Sudden,

2000
Angiotensin converting enzyme inhibition and dihydropyridine calcium channel blockade in the treatment of left ventricular hypertrophy in arterial hypertension.
    Minerva cardioangiologica, 2002, Volume: 50, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Atenolol; Calcium Channe

2002

Trials

26 trials available for nifedipine and Hypertrophy, Left Ventricular

ArticleYear
Barnidipine or Lercanidipine on Echocardiographic Parameters in Hypertensive, Type 2 Diabetics with Left Ventricular Hypertrophy: A Randomized Clinical Trial.
    Scientific reports, 2015, Aug-05, Volume: 5

    Topics: Aged; Antihypertensive Agents; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Dihydropyridines

2015
Potential protective effect of long-term therapy with Xuezhikang on left ventricular diastolic function in patients with essential hypertension.
    Journal of alternative and complementary medicine (New York, N.Y.), 2009, Volume: 15, Issue:7

    Topics: Aged; Biological Products; Blood Flow Velocity; C-Reactive Protein; Calcium Channel Blockers; Case-C

2009
Comparative effects of losartan and nifedipine therapy on exercise capacity, Doppler echocardiographic parameters and endothelin levels in patients with secondary pulmonary hypertension.
    Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2010, Volume: 10, Issue:1

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Diastol

2010
Differential effects of once-daily antihypertensive drugs on blood pressure, left ventricular mass and sympathetic activity: Nifedipine-GITS versus felodipine-ER versus enalapril.
    The Canadian journal of cardiology, 2002, Volume: 18, Issue:12

    Topics: Antihypertensive Agents; Biomarkers; Blood Pressure; Data Interpretation, Statistical; Enalapril; Fe

2002
Regression of left ventricular hypertrophy after treatment of hypertension: comparison of directed M-echocardiography with magnetic resonance imaging in quantification of serial mass changes.
    Journal of cardiac failure, 2003, Volume: 9, Issue:2

    Topics: Aged; Antihypertensive Agents; Calcium Channel Blockers; Echocardiography; Enalapril; Female; Humans

2003
Effects of nifedipine on carotid and femoral arterial wall thickness in previously untreated hypertensive patients.
    Blood pressure. Supplement, 2003, Volume: 1

    Topics: Adult; Blood Pressure; Calcium Channel Blockers; Carotid Arteries; Cholesterol; Echocardiography; Fe

2003
Effects of calcium channel antagonists on left ventricular hypertrophy and diastolic function in patients with essential hypertension.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2003, Volume: 25, Issue:8

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diastole; Dihydropyri

2003
The effect of combination therapy on regression of left ventricular hypertrophy in cases with hypertension.
    Saudi medical journal, 2004, Volume: 25, Issue:12

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Ch

2004
[Hypotensive efficacy and tolerability of combination of dihydropyridine and non-dihydropyridine calcium antagonists in the treatment of patients with arterial hypertension].
    Kardiologiia, 2007, Volume: 47, Issue:11

    Topics: Adult; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Dihydropyridines; Dose-Response Relation

2007
Indapamide reduces hypertensive left ventricular hypertrophy: an international multicenter study.
    Journal of cardiovascular pharmacology, 1993, Volume: 22 Suppl 6

    Topics: Adult; Aged; Atenolol; Blood Pressure; Double-Blind Method; Enalapril; Female; France; Humans; Hydro

1993
Differential effects of felodipine and nifedipine on 24-h blood pressure and left ventricular mass.
    American journal of hypertension, 1995, Volume: 8, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring,

1995
Comparative effects of fosinopril and nifedipine on regression of left ventricular hypertrophy in hypertensive patients: a double-blind study.
    Cardiovascular drugs and therapy, 1995, Volume: 9, Issue:1

    Topics: Blood Pressure; Blood Pressure Determination; Double-Blind Method; Drug Therapy, Combination; Echoca

1995
Normalization of cardiac structure and function after regression of cardiac hypertrophy.
    American heart journal, 1994, Volume: 128, Issue:2

    Topics: Adult; Case-Control Studies; Heart Ventricles; Hemodynamics; Humans; Hypertension; Hypertrophy, Left

1994
[The effect of nifedipine in hypertensive cardiopathy. An echocardiographic and electrocardiographic study].
    Cardiologia (Rome, Italy), 1993, Volume: 38, Issue:6

    Topics: Adult; Analysis of Variance; Echocardiography; Electrocardiography; Female; Hemodynamics; Humans; Hy

1993
[The effect of hypotensive drugs on left ventricular mass and diastolic function].
    Polskie Archiwum Medycyny Wewnetrznej, 1995, Volume: 94, Issue:1

    Topics: Adult; Aged; Antihypertensive Agents; Calcium Channel Blockers; Diastole; Drug Therapy, Combination;

1995
Comparison of enalapril versus nifedipine to decrease left ventricular hypertrophy in systemic hypertension (the PRESERVE trial).
    The American journal of cardiology, 1996, Jul-01, Volume: 78, Issue:1

    Topics: Antihypertensive Agents; Double-Blind Method; Echocardiography; Enalapril; Female; Follow-Up Studies

1996
Lisinopril reverses left ventricular hypertrophy through improved aortic compliance.
    Hypertension (Dallas, Tex. : 1979), 1996, Volume: 28, Issue:3

    Topics: Aged; Antihypertensive Agents; Aorta; Compliance; Cross-Over Studies; Echocardiography; Female; Hear

1996
[Nifedipine in the treatment of moderate and severe arterial hypertension. Long-term effect on arterial pressure and on the left ventricle].
    Revista espanola de cardiologia, 1997, Volume: 50, Issue:8

    Topics: Adult; Aged; Calcium Channel Blockers; Dose-Response Relationship, Drug; Female; Humans; Hypertensio

1997
The effects of long-term treatment on left ventricular hypertrophy in patients with essential hypertension: relation to changes in neurohumoral factors.
    Journal of cardiovascular pharmacology, 1997, Volume: 30, Issue:5

    Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atrial

1997
Regression of left ventricular hypertrophy in hypertensive patients after 1 year of treatment with rilmenidine: a double-blind, randomized, controlled (versus nifedipine) study.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1998, Volume: 16, Issue:3

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diastole; Double-Blind Met

1998
Reduction of cardiovascular structural changes by nifedipine GITS in essential hypertensive patients.
    Blood pressure, 1998, Volume: 7, Issue:3

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Delayed-Action Prepa

1998
[Clinical study on combined treatment of shuizhi tuyuan powder and nifedipine in treating hypertension patients complicated with left ventricular hypertrophy].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1996, Volume: 16, Issue:11

    Topics: Adult; Aged; Animals; Calcium Channel Blockers; Drug Therapy, Combination; Female; Humans; Hypertens

1996
Efficacy of different drug classes used to initiate antihypertensive treatment in black subjects: results of a randomized trial in Johannesburg, South Africa.
    Archives of internal medicine, 2001, Apr-09, Volume: 161, Issue:7

    Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Black Pe

2001
Effects of once-daily angiotensin-converting enzyme inhibition and calcium channel blockade-based antihypertensive treatment regimens on left ventricular hypertrophy and diastolic filling in hypertension: the prospective randomized enalapril study evaluat
    Circulation, 2001, Sep-11, Volume: 104, Issue:11

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Diastole;

2001
Relationship between treatment-induced changes in left ventricular mass and blood pressure in black african hypertensive patients: results of the Baragwanath Trial.
    Circulation, 2002, Feb-19, Volume: 105, Issue:7

    Topics: Angiotensin-Converting Enzyme Inhibitors; Black People; Blood Pressure; Body Mass Index; Calcium Cha

2002
[Effects of verapamil and nifedipine on blood pressure during rest and exertion and on left ventricular hypertrophy].
    Archives des maladies du coeur et des vaisseaux, 1992, Volume: 85, Issue:8

    Topics: Adult; Aged; Blood Pressure; Double-Blind Method; Echocardiography, Doppler; Exercise Test; Female;

1992

Other Studies

31 other studies available for nifedipine and Hypertrophy, Left Ventricular

ArticleYear
Effects of late-onset and long-term captopril and nifedipine treatment in aged spontaneously hypertensive rats: Echocardiographic studies.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2015, Volume: 38, Issue:11

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Captopril; Drug Evaluati

2015
Gene expression profiling of calcium-channel antagonists in the heart of hypertensive and normotensive rats reveals class specific effects.
    Vascular pharmacology, 2016, Volume: 87

    Topics: Animals; Calcium Channel Blockers; Diltiazem; Gene Expression Profiling; Gene Expression Regulation;

2016
Long-term administration of nifedipine attenuates cardiac remodeling and diastolic heart failure in hypertensive rats.
    European journal of pharmacology, 2009, Aug-01, Volume: 615, Issue:1-3

    Topics: Animals; Antihypertensive Agents; Calcium Channel Blockers; Collagen; Disease Models, Animal; Fibros

2009
Comparative study of vasodilators in an animal model of chronic volume overload caused by severe aortic regurgitation.
    Circulation. Heart failure, 2009, Volume: 2, Issue:1

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Aortic V

2009
Left ventricular response to sustained volume overload from chronic aortic valve regurgitation in rats.
    Journal of cardiac failure, 2003, Volume: 9, Issue:2

    Topics: Animals; Aortic Valve Insufficiency; Calcium Channel Blockers; Echocardiography; Hypertrophy, Left V

2003
Reversible left ventricular hypertrophy after tako-tsubo-like cardiomyopathy.
    Acta cardiologica, 2005, Volume: 60, Issue:1

    Topics: Aged; Aspirin; Benzimidazoles; Biphenyl Compounds; Cardiomyopathy, Dilated; Chest Pain; Drug Therapy

2005
[Efficacy of and tolerance to combined therapy with dihydropyridine and non-dihydropyridine Ca antagonists in patients with moderate arterial hypertension].
    Klinicheskaia meditsina, 2005, Volume: 83, Issue:7

    Topics: Adult; Aged; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Dose-R

2005
Vasodilators in aortic regurgitation.
    The New England journal of medicine, 2006, Jan-19, Volume: 354, Issue:3

    Topics: Aortic Valve Insufficiency; Enalapril; Humans; Hypertrophy, Left Ventricular; Nifedipine; Vasodilato

2006
Blood pressure variability, baroreflex sensitivity and organ damage in spontaneously hypertensive rats treated with various antihypertensive drugs.
    European journal of pharmacology, 2006, Aug-14, Volume: 543, Issue:1-3

    Topics: Animals; Antihypertensive Agents; Aorta; Atenolol; Baroreflex; Biphenyl Compounds; Blood Pressure; C

2006
Beneficial effects of the combination of nifedipine and losartan in hypertensive Dahl salt-sensitive rats.
    Journal of cardiovascular pharmacology, 2007, Volume: 50, Issue:1

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Blood Pressure; Calcium Channel Blockers; D

2007
[Effects of calcium antagonists on withdrawal of beta-receptor blockers in rats during left ventricular hypertrophy].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1995, Volume: 30, Issue:1

    Topics: Animals; Hemodynamics; Hypertrophy, Left Ventricular; Isomerism; Male; Metoprolol; Myocardium; Nifed

1995
[Effects of m-nifedipine on dihydropyridine binding sites in the cell membranes of kidney and lung from left ventricular hypertrophied elderly rats].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1995, Volume: 30, Issue:1

    Topics: Animals; Calcium Channels; Calcium Channels, L-Type; Cell Membrane; Hypertension, Renovascular; Hype

1995
[Effects of m-nifedipine on left ventricular diastolic function and Ca2+ content of myocardial and cerebral mitochondria and artery tissues in left ventricular hypertrophied rats].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1995, Volume: 30, Issue:1

    Topics: Animals; Aorta; Brain; Calcium; Diastole; Hypertension, Renovascular; Hypertrophy, Left Ventricular;

1995
Effect of nifedipine on pulmonary hemodynamics.
    American heart journal, 1995, Volume: 129, Issue:6

    Topics: Blood Pressure; Hemodynamics; Humans; Hypertension, Pulmonary; Hypertrophy, Left Ventricular; Nifedi

1995
Regression of left ventricular hypertrophy with long-term treatment of nifedipine in systemic hypertension.
    Clinical cardiology, 1994, Volume: 17, Issue:11

    Topics: Adult; Aged; Blood Pressure; Echocardiography; Female; Heart Rate; Humans; Hypertension; Hypertrophy

1994
[Effects of m-nifedipine and nifedipine on hemodynamics in renovascular hypertensive rats].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1994, Volume: 15, Issue:3

    Topics: Animals; Blood Pressure; Hemodynamics; Hypertension, Renovascular; Hypertrophy, Left Ventricular; In

1994
Effects of m-nifedipine on dihydropyridine binding sites in cardiac and cerebral cortex cell membranes from left ventricular hypertrophied rats.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1993, Volume: 14, Issue:5

    Topics: Animals; Binding Sites; Calcium Channels, L-Type; Cerebral Cortex; Dihydropyridines; Hypertension, R

1993
Left ventricular function of the heart regressed by nifedipine in spontaneously hypertensive rats.
    Japanese circulation journal, 1994, Volume: 58, Issue:2

    Topics: Animals; Blood Pressure; Hemodynamics; Hypertension; Hypertrophy, Left Ventricular; Male; Nifedipine

1994
[Left ventricular function in patients with arterial hypertension during the performance of acute drug tests with captopril and nifedipine].
    Terapevticheskii arkhiv, 1993, Volume: 65, Issue:8

    Topics: Adult; Captopril; Drug Evaluation; Heart Function Tests; Humans; Hypertension; Hypertrophy, Left Ven

1993
Alterations in cardiac myosin isozymes associated with aging and chronic hypertension: their modulation with nifedipine.
    Cardiovascular research, 1993, Volume: 27, Issue:10

    Topics: Aging; Animals; Chronic Disease; Electrophoresis, Polyacrylamide Gel; Hypertension; Hypertrophy, Lef

1993
[A reduction of left ventricular hypertrophy and an improvement in diastolic function after therapy with nifedipine retard in patients with hypertensive cardiopathy].
    Cardiologia (Rome, Italy), 1993, Volume: 38, Issue:9

    Topics: Adult; Aged; Delayed-Action Preparations; Diastole; Drug Evaluation; Echocardiography; Echocardiogra

1993
Blood pressure and myocardial perfusion in hypertensive patients with and without left ventricular hypertrophy.
    Journal of human hypertension, 1995, Volume: 9, Issue:12

    Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Captopril; Coron

1995
Regression of increased left ventricular masses in elderly hypertensive patients on lisinopril as assessed by magnetic resonance imaging.
    Academic radiology, 1996, Volume: 3, Issue:4

    Topics: Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents;

1996
Effects of m-nifedipine on dihydropyridine binding sites in hypertrophied left ventricular cell membranes from deoxycorticosterone acetate-salt hypertensive rats.
    Yao xue xue bao = Acta pharmaceutica Sinica, 1996, Volume: 31, Issue:5

    Topics: Animals; Binding Sites; Calcium; Calcium Channel Blockers; Desoxycorticosterone; Dihydropyridines; H

1996
Antihypertensive agents that limit ventricular hypertrophy inhibit cardiac expression of insulin-like growth factor-I.
    Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 1997, Volume: 45, Issue:9

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Enalapril; Heart; Hydralazine; Hypertension; Hyper

1997
Ultrastructural changes during myocardial hypertrophy and its regression: long-term effects of nifedipine in adult spontaneously hypertensive rats.
    Heart and vessels, 1997, Volume: 12, Issue:3

    Topics: Animals; Blood Pressure; Capillaries; Cell Size; Heart Ventricles; Hypertension; Hypertrophy, Left V

1997
Once-daily nifedipine sustained release (nifelan) on forearm vascular resistance and regression of left ventricular hypertrophy in patients with mild to moderate essential hypertension.
    Changgeng yi xue za zhi, 1998, Volume: 21, Issue:1

    Topics: Adult; Aged; Calcium Channel Blockers; Female; Forearm; Hemodynamics; Humans; Hypertension; Hypertro

1998
Effects of menidipine on dihydropyridines binding sites in cardiac and cerebral membranes from old rats with left ventricular hypertrophy.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1996, Volume: 17, Issue:3

    Topics: Animals; Brain; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Membrane;

1996
[Effects of m-Nif and Nif on left ventricle hypertrophy in rats induced by partial ligation of abdominal aorta].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1996, Volume: 31, Issue:9

    Topics: Animals; Aorta, Abdominal; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Hyp

1996
Regression of myocardial fibrosis in hypertensive heart disease: diverse effects of various antihypertensive drugs.
    Cardiovascular research, 2000, Volume: 46, Issue:2

    Topics: Animals; Antihypertensive Agents; Captopril; Collagen; Fibrosis; Hypertension, Renovascular; Hypertr

2000
Left ventricular midwall function improves with antihypertensive therapy and regression of left ventricular hypertrophy in patients with asymptomatic hypertension.
    The American journal of cardiology, 2001, Jan-01, Volume: 87, Issue:1

    Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Echocardiogr

2001