Page last updated: 2024-11-01

nifedipine and Hypertension, Renal

nifedipine has been researched along with Hypertension, Renal in 74 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Hypertension, Renal: Persistent high BLOOD PRESSURE due to KIDNEY DISEASES, such as those involving the renal parenchyma, the renal vasculature, or tumors that secrete RENIN.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the use of short-acting nifedipine for treatment of severe hypertension in children."7.71The use of short-acting nifedipine in pediatric patients with hypertension. ( Blaszak, RT; Ellis, EN; Savage, JA, 2001)
"We describe a case of gingival hyperplasia in a 36-year-old renal transplantation recipient treated with nifedipine for severe arterial hypertension."7.67Gingival hyperplasia by nifedipine. Report of a case. ( Bencini, PL; Crosti, C; Menni, S; Montagnino, G; Piccinno, R; Sala, F; Tarantino, A, 1985)
"Ten mg of Nifedipine, a Ca++ antagonist, was administered orally in 2 groups of patients; Group 1: 6 patients in hypertensive emergency and Group II: 12 patients with intractable, severe hypertension."7.66A study on the effects of nifedipine in hypertensive crises and severe hypertension. ( Hada, Y; Kamata, C; Kuramoto, K; Kuwajima, I; Matsushita, S; Murakami, M; Ueda, K, 1978)
"In patients with chronic renal failure, decrement in BP was 25/16 mmHg (systolic and diastolic BP, respectively)."6.65[Hypotensive properties of nisoldipine. Comparative study in essential, renal and renovascular hypertension]. ( Breuer, G; Kaufmann, W; Wambach, G, 1984)
"When nifedipine was given to rats at a dosage of 0."5.26Inhibition of DOC-salt and adrenal-regeneration hypertension with the calcium blocker nifedipine. ( Hall, CE; Hungerford, S, 1982)
"Monotherapy with calcium antagonists nifedipine, foridon and verapamil hydrochloride was assessed in 46 patients with chronic glomerulonephritis and arterial hypertension by hypotensive effect and changes in systemic and renal hemodynamics, water-electrolytic balance, renin-angiotensin system."5.06[Calcium antagonists in the treatment of nephrogenic hypertension]. ( Galstian, GM; Kutyrina, IM; Rogov, VA; Tareeva, IE, 1990)
"Nifedipine given by the sublingual route has been used in the treatment of 30 hypertensive emergencies in 20 children suffering from renal disease."5.06Nifedipine in hypertensive crises of infants and children. ( Abu-Chaaban, M; Herkenrath, P; Krebber, J; Roth, B, 1986)
"To evaluate the use of short-acting nifedipine for treatment of severe hypertension in children."3.71The use of short-acting nifedipine in pediatric patients with hypertension. ( Blaszak, RT; Ellis, EN; Savage, JA, 2001)
"We describe a case of gingival hyperplasia in a 36-year-old renal transplantation recipient treated with nifedipine for severe arterial hypertension."3.67Gingival hyperplasia by nifedipine. Report of a case. ( Bencini, PL; Crosti, C; Menni, S; Montagnino, G; Piccinno, R; Sala, F; Tarantino, A, 1985)
"The new calcium antagonist felodipine with a pronounced arteriolar dilating capacity was used to treat 11 patients with severe hypertension resistant to treatment (4 with essential hypertension, 5 with renoparechymatous hypertension, 2 with renovascular hypertension)."3.67Renal effects of felodipine in hypertensive patients with reduced renal function. ( Aurell, M; Björck, S; Granérus, G; Herlitz, H, 1985)
"Ten mg of Nifedipine, a Ca++ antagonist, was administered orally in 2 groups of patients; Group 1: 6 patients in hypertensive emergency and Group II: 12 patients with intractable, severe hypertension."3.66A study on the effects of nifedipine in hypertensive crises and severe hypertension. ( Hada, Y; Kamata, C; Kuramoto, K; Kuwajima, I; Matsushita, S; Murakami, M; Ueda, K, 1978)
"We examined the progression of coronary atherosclerosis, as measured by dual-section spiral computed tomography, using the total coronary artery calcium score as a quantitative measure of the burden of atherosclerosis."2.71Accelerated coronary artery calcification in mildly reduced renal function of high-risk hypertensives: a 3-year prospective observation. ( Bursztyn, M; Grossman, E; Motro, M; Shemesh, J, 2003)
"Treatment with enalapril was associated with a greater reduction in albuminuria than with nifedipine in the entire patient group, and especially in those with microalbuminuria."2.69Long-term effects of angiotensin-converting enzyme inhibition and metabolic control in hypertensive type 2 diabetic patients. ( Chan, JC; Cheung, MY; Cheung, RC; Cockram, CS; Critchley, JA; Ko, GT; Leung, DH; Nicholls, MG; So, WY; Swaminathan, R, 2000)
"In patients with chronic renal failure, decrement in BP was 25/16 mmHg (systolic and diastolic BP, respectively)."2.65[Hypotensive properties of nisoldipine. Comparative study in essential, renal and renovascular hypertension]. ( Breuer, G; Kaufmann, W; Wambach, G, 1984)
"Nifedipine treatment or removal of external calcium (Cao2+) reduced the norepinephrine-induced peak response."1.33Enhanced response to AVP in the interlobular artery from the spontaneously hypertensive rat. ( Hansen, FH; Iversen, BM; Vågnes, ØB, 2005)
" The hypotensive effect of YM430 reached its maximum about 2 hr after dosing and lasted for over 10 hr."1.30Hypotensive effects of YM430, a 1,4-dihydropyridine derivative, in spontaneously hypertensive rats and renal hypertensive dogs. ( Shibasaki, K; Takenaka, T; Takizawa, K; Uchida, W, 1997)
" No tolerance to the antihypertensive effect of KRN4884 was observed during a 15-day repeated dosing period."1.30KRN4884, a novel K channel opener: antihypertensive effects in conscious renal hypertensive dogs. ( Endo, M; Izawa, T; Izumi, H; Jinno, Y; Kawahara, J; Takeuchi, A, 1997)
"3-3 mg/kg), dose-response curves of the antihypertensive effect did not change and body weight gain was equal to that of the vehicle-treated group."1.28Antihypertensive effects of MPC-1304, a novel calcium antagonist, in experimental hypertensive rats and dogs. ( Haruno, A; Kanda, A; Miyake, H; Nagasaka, M, 1992)
"1 mg/kg) occurred during an 8-week repeated daily dosing to RHD and plasma renin activity, and aldosterone levels were not elevated during this period."1.28Y-27152, a long-acting K+ channel opener with less tachycardia: antihypertensive effects in hypertensive rats and dogs in conscious state. ( Aoki, K; Fukunari, A; Katoh, A; Nakajima, T; Setoguchi, M; Shinagawa, K; Shinohara, T; Tahara, T; Yamanaka, T; Yaoka, O, 1992)
"2 mg/kg/day for 20 days) chronically receiving AML, there was an enhancement of the antihypertensive effect of AML within a few days after starting chronic dosing, and thereafter a significant reduction of BP at 24 hr after dosing and constant effects of AML during subsequent treatment."1.28[Antihypertensive effects of amlodipine, a new calcium antagonist]. ( Ishiko, J; Munehasu, S; Suzuki, M; Yamanaka, K, 1991)
"Diabetic nephropathy is the dominant cause of hypertension in insulin-dependent diabetics, and long-term rigid antihypertensive treatment inhibits the progression of nephropathy, probably even when there is renal insufficiency."1.28The effect of antihypertensive treatment on kidney function in insulin-dependent (type I) diabetics with renal failure. ( Conde, N; Gums, G; Heinke, P; Schulz, B; Strese, J; Zander, E; Zander, G, 1990)
"When nitrendipine was combined with thiazides, a lowering of plasma potassium levels could be found, which, however, did not necessitate any therapy."1.27Safety aspects of long-term nitrendipine therapy. ( Corsing, C; Deck, K; Ingram, C; Stoepel, K; Vanov, SK, 1984)
" The long-term administration of nifedipine, 20-30 mg/kg body weight enhanced the diuretic and natriuretic response to saline loading in members of both strains."1.27Nifedipine corrects the blunted renal response to saline loading in hypertension-prone SBH rats. ( Ben-Ishay, D; Garthoff, B; Kazda, S; Mekler, J, 1987)
" Nisoldipine had the lowest maximum plasma concentration and the longest elimination half-life among the four 1,4-dihydropyridines, resulting in no significant difference in the area under the plasma concentration-time curve."1.27Comparative study on acute antihypertensive effects and pharmacokinetics of nisoldipine, nifedipine, nimodipine and nicardipine administered orally to conscious renal hypertensive dogs. ( Kato, H; Takata, Y, 1986)
"When nifedipine was given to rats at a dosage of 0."1.26Inhibition of DOC-salt and adrenal-regeneration hypertension with the calcium blocker nifedipine. ( Hall, CE; Hungerford, S, 1982)
"Nisoldipine has a long lasting antihypertensive action (12 hr at 0."1.26Nisoldipine (BAY K 5552), a new calcium antagonist. Antihypertensive effect in conscious, unrestrained renal hypertensive dogs. ( Knorr, A, 1982)
"Nitrendipine was found about 20 times more potent in its antihypertensive action than hydralazine."1.26Effect of a new calcium antagonist, nitrendipine, on blood pressure and heart rate of conscious, unrestrained dogs. ( Knorr, A; Stoepel, K, 1981)
" Substantial and prolonged falls in blood pressure were observed following oral dosing with 3 mg/kg of nifedipine in renal hypertensive rats, with 10 mg/kg of nifedipine in normotensive and spontaneously hypertensive rats and with 10 mg/dg of hydralazine in all three groups of animals."1.26Antihypertensive effects of nifedipine on conscious normotensive and hypertensive rats. ( Fujie, K; Kubo, T; Misu, Y; Yamashita, M, 1981)
" of niludipine a fall of blood pressure was marked at its peak effect attained about 45 min after dosing and lasted about 3 h."1.26Antihypertensive effect of Niludipine (Bay a 7168) on conscious renal-hypertensive dogs. ( Hiwatari, M; Taira, N, 1979)

Research

Studies (74)

TimeframeStudies, this research(%)All Research%
pre-199041 (55.41)18.7374
1990's24 (32.43)18.2507
2000's8 (10.81)29.6817
2010's1 (1.35)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Xie, HH1
Zhang, XF1
Chen, YY1
Shen, FM1
Su, DF1
Nakagawa, N1
Fujino, T1
Kabara, M1
Matsuki, M1
Chinda, J1
Kikuchi, K1
Hasebe, N1
Srinivas, TR1
Meier-Kriesche, HU1
Kaplan, B1
Bennett, WM1
Bursztyn, M1
Motro, M1
Grossman, E1
Shemesh, J1
Hansen, FH1
Vågnes, ØB1
Iversen, BM1
Shih, HC1
Lee, TH1
Chen, SC1
Li, CY1
Shibuya, T1
Stoepel, K3
Deck, K1
Corsing, C1
Ingram, C1
Vanov, SK1
Lin, CI1
Lu, HH1
Lin, KY1
Ambroso, GC1
Como, G1
Scalamogna, A1
Citterio, A1
Casati, S1
Cantaluppi, A1
Ponticelli, C1
Wambach, G1
Breuer, G1
Kaufmann, W1
Kusano, E1
Asano, Y1
Takeda, K1
Matsumoto, Y1
Ebihara, A1
Hosoda, S1
Morita, T1
Kanazawa, T1
Ito, K1
Nose, T2
Hall, CE1
Hungerford, S1
Knorr, A2
Eliahou, HE1
Iaina, A1
Schneider, R1
Cohen, D1
Goldfarb, D1
Gross, M1
Heise, A1
Kazda, S2
Kubo, T1
Fujie, K1
Yamashita, M1
Misu, Y1
Mulvany, MJ1
Korsgaard, N1
Nyborg, N1
Ishii, H1
Itoh, K1
Moncica, I1
Oh, PI1
ul Qamar, I1
Scolnik, D1
Arbus, GS1
Hebert, D1
Balfe, JW1
Koren, G1
Griffin, KA1
Picken, MM1
Bidani, AK1
Zucchelli, P2
Zuccalà, A2
Hojo, M1
Tanaka, Y1
Katayama, O1
Teramoto, N1
Wight, JP1
Brown, CB1
el Nahas, AM1
Dworkin, LD1
Benstein, JA1
Parker, M1
Tolbert, E1
Feiner, HD1
Tack, I1
Rostaing, L1
Tran-Van, T1
Lloveras, JJ1
Durand, D1
Suc, JM1
Ader, JL1
de Silva, DG1
Fernando, AJ1
Law, F1
Jayantha, UK1
Grekas, D1
Dioudis, C1
Kalevrosoglou, I1
Alivanis, P1
Derveniotis, V1
Tourkantonis, A1
Shibasaki, K1
Takizawa, K1
Uchida, W1
Takenaka, T1
Kawahara, J1
Jinno, Y1
Endo, M1
Izumi, H1
Takeuchi, A1
Izawa, T1
Ikeda, Y1
Sakemi, T1
Yamada, M1
Matsumoto, J1
Yamaguchi, K1
Callera, GE1
Bendhack, LM1
Chan, JC1
Ko, GT1
Leung, DH1
Cheung, RC1
Cheung, MY1
So, WY1
Swaminathan, R1
Nicholls, MG1
Critchley, JA1
Cockram, CS1
Blaszak, RT1
Savage, JA1
Ellis, EN1
Leoncini, G1
Martinoli, C1
Viazzi, F1
Ravera, M1
Parodi, D1
Ratto, E1
Vettoretti, S1
Tomolillo, C1
Derchi, LE1
Deferrari, G1
Pontremoli, R1
Nicita-Mauro, V1
Barbera, N1
Savica, V1
Frisina, N1
Ceruso, D1
Zennaro, P1
Borso, MT1
Conte, A1
Hiwatari, M2
Satoh, K1
Taira, N2
Kuwajima, I1
Ueda, K1
Kamata, C1
Matsushita, S1
Kuramoto, K1
Murakami, M1
Hada, Y1
Kanda, A1
Haruno, A1
Miyake, H1
Nagasaka, M1
Borghi, M1
Fusaroli, M1
Sasdelli, M1
Stallone, C1
Sanna, G1
Gaggi, R1
Uchiyama, M1
Sakai, K1
Onoyama, K1
Nakajima, T1
Shinohara, T1
Yaoka, O1
Fukunari, A1
Shinagawa, K1
Aoki, K1
Katoh, A1
Yamanaka, T1
Setoguchi, M1
Tahara, T1
Abu-Romeh, SH1
el-Khatib, D1
Rashid, A1
Patel, M1
Osman, N1
Fayyad, M1
Scheikhoni, A1
Higazi, AS1
Gurgenian, SV1
Mikaelian, ES1
Dzhandzhapanian, AZ1
Babaian, AS1
Yamanaka, K1
Suzuki, M1
Munehasu, S1
Ishiko, J1
Langevitz, P1
Buskila, D1
Lee, P1
Hercz, G1
Tareeva, IE1
Kutyrina, IM1
Galstian, GM1
Rogov, VA1
Zander, E1
Conde, N1
Heinke, P1
Zander, G1
Strese, J1
Gums, G1
Schulz, B1
Bencini, PL1
Crosti, C1
Sala, F1
Montagnino, G1
Tarantino, A1
Menni, S1
Piccinno, R1
Spedding, M1
DiFrancesco, GF1
Mir, AK1
Petty, MA1
Berg, C1
Gittos, M1
Mekler, J1
Ben-Ishay, D1
Garthoff, B1
Ogborn, MR1
Crocker, JF1
Grimm, PC1
Schiffl, H1
Mickisch, O1
Schmid, M1
Mann, JF1
Helder, T1
Bergen, F1
Rauterberg, EW1
Ritz, E1
Plaza de los Reyes, M1
Plaza de los Reyes, X1
Hamilton, CA1
Jardine, E1
Sumner, DJ1
Reid, JL1
Ishii, K1
Kano, T1
Ando, J1
Yoshida, H1
Riegel, W1
Hörl, WH1
Heidland, A1
Ohtsuka, M1
Koibuchi, Y1
Sakai, S1
Tsujioka, K1
Fujiwara, T1
Ozaki, T1
Maeda, K1
Motoyama, I1
Horiai, H1
Ono, T1
Karasawa, A1
Ikeda, J1
Yamada, K1
Kubo, K1
Oka, T1
Nakamizo, N1
Tasaka, K1
Kamei, C1
Tagami, H1
Hokonohara, T1
Sugimoto, Y1
Roth, B1
Herkenrath, P1
Krebber, J1
Abu-Chaaban, M1
Marchini, F1
Luca, C1
Valli, L1
Pacei, E1
Yamaura, T1
Kase, N1
Kita, H1
Uematsu, T1
Narita, H1
Yabana, H1
Saso, Y1
Suzuki, T1
Mizobe, M1
Nagao, T1
Minobe, M1
Kimura, Y1
Fukui, H1
Tanaka, M1
Okamoto, M1
Morino, A1
Miura, A1
Kimura, K1
Enomoto, H1
Takata, Y1
Kato, H1
Marmo, E1
Herlitz, H1
Aurell, M1
Björck, S1
Granérus, G1
Moreira, J1
Barata, JD1
Olias, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Role of Renal Doppler Ultrasound in Early Detection of Acute Kidney Injury in Critically Ill Patients[NCT03902483]80 participants (Anticipated)Observational2019-07-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for nifedipine and Hypertension, Renal

ArticleYear
Pharmacological treatment of renal parenchymal hypertension.
    Contributions to nephrology, 1994, Volume: 106

    Topics: Antihypertensive Agents; Captopril; Humans; Hypertension, Renal; Incidence; Kidney Diseases; Models,

1994

Trials

14 trials available for nifedipine and Hypertension, Renal

ArticleYear
Angiotensin II receptor blocker and long-acting calcium channel blocker combination therapy decreases urinary albumin excretion while maintaining glomerular filtration rate.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles

2011
Accelerated coronary artery calcification in mildly reduced renal function of high-risk hypertensives: a 3-year prospective observation.
    Journal of hypertension, 2003, Volume: 21, Issue:10

    Topics: Aged; Benzothiadiazines; Calcinosis; Calcium Channel Blockers; Coronary Artery Disease; Diuretics; F

2003
[Hypotensive properties of nisoldipine. Comparative study in essential, renal and renovascular hypertension].
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:5

    Topics: Adult; Aged; Aldosterone; Calcium Channel Blockers; Electrolytes; Female; Heart Rate; Humans; Hydroc

1984
A crossover comparison of extended release felodipine with prolonged action nifedipine in hypertension.
    Archives of disease in childhood, 1995, Volume: 73, Issue:2

    Topics: Adolescent; Antihypertensive Agents; Child; Cross-Over Studies; Delayed-Action Preparations; Drug Ad

1995
Renal functional reserve in calcium channel blocker-treated hypertensive recipients of kidney transplant.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1995, Volume: 10 Suppl 6

    Topics: Adult; Amino Acids; Calcium Channel Blockers; Cyclosporine; Female; Glomerular Filtration Rate; Huma

1995
Experience with sublingual nifedipine in paediatric hypertensive emergencies.
    The Ceylon medical journal, 1995, Volume: 40, Issue:4

    Topics: Acute Disease; Administration, Sublingual; Child; Child, Preschool; Emergencies; Female; Humans; Hyp

1995
Renal hemodynamics in hypertensive renal allograft recipients: effects of calcium antagonists and ACE inhibitors.
    Kidney international. Supplement, 1996, Volume: 55

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Female; G

1996
Long-term effects of angiotensin-converting enzyme inhibition and metabolic control in hypertensive type 2 diabetic patients.
    Kidney international, 2000, Volume: 57, Issue:2

    Topics: Aged; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Creatinine; Diabetes Mellitus, Type 2;

2000
Changes in renal resistive index and urinary albumin excretion in hypertensive patients under long-term treatment with lisinopril or nifedipine GITS.
    Nephron, 2002, Volume: 90, Issue:2

    Topics: Adult; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blocke

2002
Long-term comparison between captopril and nifedipine in the progression of renal insufficiency.
    Kidney international, 1992, Volume: 42, Issue:2

    Topics: Adolescent; Adult; Aged; Blood Pressure; Captopril; Creatinine; Female; Humans; Hypertension, Renal;

1992
Comparative effects of enalapril and nifedipine on renal hemodynamics in hypertensive renal allograft recipients.
    Clinical nephrology, 1992, Volume: 37, Issue:4

    Topics: Adult; Azathioprine; Cyclosporine; Enalapril; Female; Humans; Hypertension, Renal; Kidney Transplant

1992
[Calcium antagonists in the treatment of nephrogenic hypertension].
    Klinicheskaia meditsina, 1990, Volume: 68, Issue:8

    Topics: Adolescent; Adult; Calcium Channel Blockers; Glomerulonephritis; Hemodynamics; Humans; Hypertension,

1990
[Calcium antagonists in chronic renal failure. Undesirable effects on glomerular hemodynamics?].
    Deutsche medizinische Wochenschrift (1946), 1988, Oct-07, Volume: 113, Issue:40

    Topics: Adult; Albuminuria; Calcium Channel Blockers; Enalapril; Hemodynamics; Humans; Hypertension, Renal;

1988
Nifedipine in hypertensive crises of infants and children.
    Clinical and experimental hypertension. Part A, Theory and practice, 1986, Volume: 8, Issue:4-5

    Topics: Adolescent; Blood Pressure; Child; Child, Preschool; Clinical Trials as Topic; Emergencies; Humans;

1986

Other Studies

59 other studies available for nifedipine and Hypertension, Renal

ArticleYear
Synergism of hydrochlorothiazide and nifedipine on blood pressure variability reduction and organ protection in spontaneously hypertensive rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2008, Volume: 31, Issue:4

    Topics: Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Calcium Channel Blockers; Drug Synergi

2008
Response to "Sustained improvement of renal graft function for two years in hypertensive renal transplant recipients treated with nifedipine as compared with lisinopril".
    Transplantation, 2002, Jul-15, Volume: 74, Issue:1

    Topics: Antihypertensive Agents; Calcium Channel Blockers; Humans; Hypertension, Renal; Kidney Transplantati

2002
Enhanced response to AVP in the interlobular artery from the spontaneously hypertensive rat.
    American journal of physiology. Renal physiology, 2005, Volume: 288, Issue:5

    Topics: Animals; Arginine Vasopressin; Arterioles; Calcium Channel Blockers; Calcium Signaling; Hypertension

2005
Anti-hypertension effects of traditional Chinese medicine ju-ling-tang on renal hypertensive rats.
    The American journal of Chinese medicine, 2005, Volume: 33, Issue:6

    Topics: Animals; Antihypertensive Agents; Biopsy; Coronary Vessels; Disease Models, Animal; Drugs, Chinese H

2005
Safety aspects of long-term nitrendipine therapy.
    Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 7

    Topics: Calcium Channel Blockers; Drug Therapy, Combination; Electrocardiography; Humans; Hydrochlorothiazid

1984
Adrenergic receptors and increased reactivity of aortic smooth muscle in renal hypertensive rats.
    Journal of the autonomic nervous system, 1982, Volume: 5, Issue:3

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Pressure; Caffeine; Calcium; Dose-Response Relationsh

1982
Slow-release nifedipine for treatment of arterial hypertension in patients with chronic renal failure.
    Contributions to nephrology, 1984, Volume: 41

    Topics: Adult; Aged; Delayed-Action Preparations; Female; Humans; Hypertension, Renal; Kidney Failure, Chron

1984
Hypotensive effect of nifedipine in hypertensive patients with chronic renal failure.
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:12

    Topics: Adolescent; Adult; Calcium; Cardiac Output; Epinephrine; Female; Hemodynamics; Humans; Hypertension,

1982
Antihypertensive effect of KB-944, a new calcium antagonist, in conscious normotensive and hypertensive rats.
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:9

    Topics: Animals; Antihypertensive Agents; Benzothiazoles; Blood Pressure; Calcium Channel Blockers; Desoxyco

1982
Inhibition of DOC-salt and adrenal-regeneration hypertension with the calcium blocker nifedipine.
    Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:7

    Topics: Adrenal Glands; Adrenalectomy; Animals; Blood Pressure; Desoxycorticosterone; Female; Heart Rate; Hy

1982
Nisoldipine (BAY K 5552), a new calcium antagonist. Antihypertensive effect in conscious, unrestrained renal hypertensive dogs.
    Archives internationales de pharmacodynamie et de therapie, 1982, Volume: 260, Issue:1

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dogs; Female; Heart Rate

1982
Treatment of hypertension in dialysis and essential hypertension patients with nifedipine.
    Clinical and experimental dialysis and apheresis, 1982, Volume: 6, Issue:4

    Topics: Humans; Hypertension, Renal; Kidney Failure, Chronic; Nifedipine; Pyridines; Renal Dialysis; Time Fa

1982
Pharmacological studies of the antihypertensive effect of nitrendipine.
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:12

    Topics: Animals; Antihypertensive Agents; Blood Flow Velocity; Calcium Channel Blockers; Cardiac Output; Dog

1981
Effect of a new calcium antagonist, nitrendipine, on blood pressure and heart rate of conscious, unrestrained dogs.
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:12

    Topics: Animals; Blood Pressure; Calcium Channel Blockers; Dogs; Dose-Response Relationship, Drug; Female; H

1981
Antihypertensive effects of nifedipine on conscious normotensive and hypertensive rats.
    Journal of pharmacobio-dynamics, 1981, Volume: 4, Issue:4

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Heart Rate; Hydralazine; Hypertension; Hypertensio

1981
Evidence that the increased calcium sensitivity of resistance vessels in spontaneously hypertensive rats is an intrinsic defect of their vascular smooth muscle.
    Clinical and experimental hypertension, 1981, Volume: 3, Issue:4

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium; Disease Models, Animal; Felodipine; Hyper

1981
Different antihypertensive effects of nifedipine in conscious experimental hypertensive and normotensive rats.
    European journal of pharmacology, 1980, May-30, Volume: 64, Issue:1

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Desoxycorticosterone; Heart Rate; Hydralazine; Hyp

1980
Deleterious effects of calcium channel blockade on pressure transmission and glomerular injury in rat remnant kidneys.
    The Journal of clinical investigation, 1995, Volume: 96, Issue:2

    Topics: Animals; Enalapril; Feedback; Hypertension, Renal; Infarction; Kidney; Male; Nephrectomy; Nifedipine

1995
Acute antihypertensive effects of the new generation calcium antagonist 3-pyridine carboxylic acid 5-[(cyclopropylamino)-carbonyl]-1,4-dihydro-2,6-dimethyl-4-(2-nitrophen yl) octyl ester on conscious spontaneously hypertensive rats and renal hypertensive
    Arzneimittel-Forschung, 1993, Volume: 43, Issue:8

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Dose-R

1993
Effect of control of hypertension on progressive renal failure.
    Clinical nephrology, 1993, Volume: 39, Issue:6

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Female; Follow-Up Studies; Humans; Hypertension, Ren

1993
Calcium antagonists and converting enzyme inhibitors reduce renal injury by different mechanisms.
    Kidney international, 1993, Volume: 43, Issue:4

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Enalapril; Glomeruloscl

1993
Hypotensive effects of YM430, a 1,4-dihydropyridine derivative, in spontaneously hypertensive rats and renal hypertensive dogs.
    Japanese journal of pharmacology, 1997, Volume: 73, Issue:2

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Calcium Channel

1997
KRN4884, a novel K channel opener: antihypertensive effects in conscious renal hypertensive dogs.
    Journal of cardiovascular pharmacology, 1997, Volume: 29, Issue:6

    Topics: Animals; Antihypertensive Agents; Benzopyrans; Calcium Channel Blockers; Cromakalim; Dogs; Female; H

1997
Successful combined therapy of nifedipine and diltiazem for severe hypertension in a maintenance hemodialysis patient.
    Clinical nephrology, 1999, Volume: 51, Issue:2

    Topics: Calcium Channel Blockers; Diltiazem; Drug Therapy, Combination; Humans; Hypertension, Renal; Male; M

1999
Contribution of sarcoplasmic reticulum calcium uptake and L-type calcium channels to altered vascular responsiveness in the aorta of renal hypertensive rats.
    General pharmacology, 1999, Volume: 33, Issue:6

    Topics: Animals; Aorta; Caffeine; Calcium; Calcium Channels, L-Type; Hypertension, Renal; In Vitro Technique

1999
The use of short-acting nifedipine in pediatric patients with hypertension.
    The Journal of pediatrics, 2001, Volume: 139, Issue:1

    Topics: Adolescent; Antihypertensive Agents; Blood Pressure; Body Weight; Case-Control Studies; Child; Child

2001
[Treatment of hypertensive crises with calcium antagonists].
    Bollettino della Societa italiana di cardiologia, 1978, Volume: 23, Issue:9

    Topics: Antihypertensive Agents; Calcium; Drug Therapy, Combination; Humans; Hypertension; Hypertension, Ren

1978
[Effects of nifedipine on arterial hypertension: study of 26 cases].
    Bollettino della Societa italiana di cardiologia, 1978, Volume: 23, Issue:9

    Topics: Adult; Aged; Humans; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Male; Middle Age

1978
Antihypertensive effect of nifedipine on conscious renal-hypertensive dogs.
    Arzneimittel-Forschung, 1979, Volume: 29, Issue:2

    Topics: Animals; Antihypertensive Agents; Dogs; Female; Hemodynamics; Hydralazine; Hypertension, Renal; Male

1979
Antihypertensive effect of Niludipine (Bay a 7168) on conscious renal-hypertensive dogs.
    Arzneimittel-Forschung, 1979, Volume: 29, Issue:9

    Topics: Animals; Blood Pressure; Dogs; Drug Interactions; Female; Heart Rate; Hypertension, Renal; Isoproter

1979
A study on the effects of nifedipine in hypertensive crises and severe hypertension.
    Japanese heart journal, 1978, Volume: 19, Issue:4

    Topics: Adult; Aged; Blood Pressure; Calcium; Cardiac Output; Female; Humans; Hypertension; Hypertension, Re

1978
Antihypertensive effects of MPC-1304, a novel calcium antagonist, in experimental hypertensive rats and dogs.
    Journal of cardiovascular pharmacology, 1992, Volume: 20, Issue:5

    Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Co

1992
Rectal administration of perforated nifedipine capsules in acute severe hypertension in children.
    The British journal of clinical practice, 1992,Summer, Volume: 46, Issue:2

    Topics: Acute Disease; Administration, Rectal; Adolescent; Capsules; Child; Child, Preschool; Humans; Hypert

1992
[Secondary kidney disease due to hypertension].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1992, Jan-10, Volume: 81, Issue:1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Humans; Hypertension, Renal; Nephrosclerosis; N

1992
Y-27152, a long-acting K+ channel opener with less tachycardia: antihypertensive effects in hypertensive rats and dogs in conscious state.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 261, Issue:2

    Topics: Administration, Oral; Animals; Antihypertensive Agents; Benzopyrans; Blood Pressure; Cromakalim; Dog

1992
Efficacy of intravenous verapamil in arterial hypertension refractory to three-step antihypertensive therapy.
    Cor et vasa, 1991, Volume: 33, Issue:5

    Topics: Adult; Antihypertensive Agents; Clonidine; Echocardiography; Female; Hemodynamics; Humans; Hydrochlo

1991
[Antihypertensive effects of amlodipine, a new calcium antagonist].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1991, Volume: 97, Issue:2

    Topics: Administration, Oral; Amlodipine; Animals; Calcium Channel Blockers; Dogs; Dose-Response Relationshi

1991
Scleroderma hypertensive renal crisis and the changing pattern of mortality in systemic sclerosis (scleroderma)
    Nephron, 1991, Volume: 57, Issue:1

    Topics: Adult; Captopril; Female; Humans; Hydralazine; Hypertension, Renal; Kidney; Male; Middle Aged; Minox

1991
The effect of antihypertensive treatment on kidney function in insulin-dependent (type I) diabetics with renal failure.
    Experimental and clinical endocrinology, 1990, Volume: 95, Issue:1

    Topics: Acute Kidney Injury; Antihypertensive Agents; Blood Pressure; Creatinine; Diabetes Mellitus, Type 1;

1990
Gingival hyperplasia by nifedipine. Report of a case.
    Acta dermato-venereologica, 1985, Volume: 65, Issue:4

    Topics: Adult; Gingival Hyperplasia; Humans; Hypertension, Renal; Kidney Transplantation; Male; Nifedipine

1985
MDL 72567, a dihydropyridine calcium-antagonist, that causes vasodilation and direct sinus bradycardia.
    Journal of cardiovascular pharmacology, 1987, Volume: 10, Issue:1

    Topics: Animals; Bradycardia; Calcium Channel Blockers; Calcium Channels; Decerebrate State; Dihydropyridine

1987
Nifedipine corrects the blunted renal response to saline loading in hypertension-prone SBH rats.
    Journal of cardiovascular pharmacology, 1987, Volume: 9 Suppl 1

    Topics: Animals; Blood Pressure; Diuretics; Female; Hypertension, Renal; Kidney; Natriuresis; Nifedipine; Ra

1987
Nifedipine, verapamil and cyclosporin A pharmacokinetics in children.
    Pediatric nephrology (Berlin, Germany), 1989, Volume: 3, Issue:3

    Topics: Child; Child, Preschool; Cyclosporins; Drug Interactions; Humans; Hypertension, Renal; Kidney Transp

1989
Platelet cytosolic free calcium concentration in hypertension associated with early stage kidney disease.
    Klinische Wochenschrift, 1989, Jul-03, Volume: 67, Issue:13

    Topics: Adult; Blood Platelets; Calcium; Cytosol; Drug Therapy, Combination; Female; Glomerular Filtration R

1989
[Depot nifedipine in the treatment of patients with essential and renal hypertension without renal insufficiency].
    Revista medica de Chile, 1985, Volume: 113, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Delayed-Action Preparations; Drug Administration Schedule; Drug

1985
The effects of calcium antagonists on blood pressure and responses to alpha-adrenoceptor agonists in hypertensive rabbits.
    Clinical and experimental pharmacology & physiology, 1987, Volume: 14, Issue:2

    Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Pressure; Calcium Channel Blockers; Drug Interac

1987
Binding of [3H]nitrendipine to cardiac and cerebral membranes from normotensive and renal, deoxycorticosterone/NaCl and spontaneously hypertensive rats.
    European journal of pharmacology, 1986, Apr-16, Volume: 123, Issue:2

    Topics: Animals; Binding Sites; Brain; Desoxycorticosterone; Hypertension; Hypertension, Renal; In Vitro Tec

1986
Long-term effects of nifedipine on carbohydrate and lipid metabolism in hypertensive hemodialyzed patients.
    Klinische Wochenschrift, 1986, Oct-31, Volume: 64, Issue:21

    Topics: Adult; Blood Glucose; Cholesterol; Citrates; Citric Acid; Female; Glucagon; Humans; Hypertension, Re

1986
Effects of nilvadipine on the cardiovascular system in experimental animals.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:11

    Topics: Animals; Calcium; Calcium Channel Blockers; Coronary Disease; Coronary Vessels; Dogs; Female; Guinea

1988
Antihypertensive effects of the new calcium antagonist benidipine hydrochloride in conscious, renal-hypertensive dogs.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:11A

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chemical Phenomena; Chem

1988
Antihypertensive effects of nisoldipine and reference drugs in certain types of hypertensive rats.
    Arzneimittel-Forschung, 1987, Volume: 37, Issue:3

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Desoxycorticosterone; Hypertension; Hypertension,

1987
[Anti-hypertensive activity of P0285 and nifedipine in conscious normotensive rats and in rats with spontaneous, renal and desoxycorticosterone acetate-induced hypertension].
    Cardiologia (Rome, Italy), 1987, Volume: 32, Issue:7

    Topics: Animals; Calcium Channel Blockers; Desoxycorticosterone; Dihydropyridines; Heart Rate; Hypertension;

1987
Antihypertensive and cardiovascular effects of the new dihydropyridine derivative methyl (E)-3-phenyl-2-propen-1-yl-1,4-dihydro-2,6-dimethyl- 4-(3-nitrophenyl)pyridine-3,5-dicarboxylate.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:1

    Topics: Anesthesia, General; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dih

1986
Hypotensive action of diltiazem in conscious renal hypertensive dogs: comparison with nifedipine and interaction with pindolol.
    Journal of pharmacobio-dynamics, 1986, Volume: 9, Issue:6

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Diltiazem; Dogs; Electrocardiography; Heart Rate;

1986
Antihypertensive effects of a new dihydropyridine calcium antagonist.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:9

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cats; Dihydropyridines;

1986
Comparative study on acute antihypertensive effects and pharmacokinetics of nisoldipine, nifedipine, nimodipine and nicardipine administered orally to conscious renal hypertensive dogs.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:10

    Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Dogs; Dose-Response Relation

1986
On the mechanism of the anti-hypertensive effect of Ca++-blockers.
    Research communications in chemical pathology and pharmacology, 1986, Volume: 51, Issue:1

    Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dogs; Heart

1986
Renal effects of felodipine in hypertensive patients with reduced renal function.
    Drugs, 1985, Volume: 29 Suppl 2

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Felodipine; Female; Glomerular Filtration Rate

1985
Antihypertensive action of calcium blockade in hypertensive patients with chronic renal disease.
    Nephron, 1985, Volume: 41, Issue:4

    Topics: Adult; Aged; Blood Pressure; Chronic Disease; Drug Therapy, Combination; Female; Humans; Hypertensio

1985