Page last updated: 2024-11-01

nifedipine and Hypertension, Pulmonary

nifedipine has been researched along with Hypertension, Pulmonary in 265 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Hypertension, Pulmonary: Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES.

Research Excerpts

ExcerptRelevanceReference
"This study was designed to determine whether calcium antagonists, diltiazem and nifedipine, can depress low temperature-induced pulmonary hypertension (PH) in broilers (also known as ascites) and to characterize their efficacy on hemodynamics and pulmonary artery function."9.14Calcium antagonists, diltiazem and nifedipine, protect broilers against low temperature-induced pulmonary hypertension and pulmonary vascular remodeling. ( Gao, M; Guo, Y; Qiao, J; Yang, Y, 2010)
" Long-term therapy with aerosolized iloprost (long-acting PGI(2) analog) resulted in unequivocal clinical improvement from a state of immobilization and severe resting dyspnea in a patient with decompensated right heart failure."9.09Inhaled prostacyclin and iloprost in severe pulmonary hypertension secondary to lung fibrosis. ( Ghofrani, HA; Grimminger, F; Olschewski, H; Schermuly, R; Seeger, W; Temmesfeld-Wollbruck, B; Walmrath, D, 1999)
"The clinical course in primary pulmonary hypertension (PPH) is improved by calcium channel blocker therapy in those with a favorable hemodynamic response during a trial of high-dose oral nifedipine."9.09Echocardiographic predictors of an adverse response to a nifedipine trial in primary pulmonary hypertension: diminished left ventricular size and leftward ventricular septal bowing. ( Armstrong, WF; Bach, DS; Bossone, E; Ricciardi, MJ; Rubenfire, M, 1999)
"The objective of this study was to evaluate the long-term results of an 18 months nifedipine treatment in patients with pulmonary hypertension (PHT) secondary to chronic obstructive broncho-pulmonary disease (COBPD)."9.06[Long-term treatment of pulmonary hypertension in chronic obstructive bronchopneumopathies with nifedipine. Hemodynamic study over 18 months]. ( Arnaud, A; Philip-Joet, F; Saadjian, A; Vestri, R, 1989)
"A two-year-old child dying of pulmonary hypertension and cor pulmonale secondary to bronchopulmonary dysplasia, was demonstrated to have reactive pulmonary hypertension in response to 100% oxygen and isoproterenol infusion."9.06Treatment of pulmonary hypertension with diltiazem in a child with bronchopulmonary dysplasia. ( Bingham, WT; Duncan, WJ; Kasian, GF; Mersal, A; Ninan, A; Sankaran, K; Tyrrell, MJ, 1988)
"Meta-analysis of the trials of nifedipine therapy in patients with pulmonary hypertension demonstrated a decrease in pulmonary artery pressure that was associated with an amelioration of clinical symptoms."8.79Meta-analysis of the long-term effect of nifedipine for pulmonary hypertension. ( Lehrman, S; Malik, AS; Warshafsky, S, 1997)
"We have studied the prophylactic administration of nifedipine and its molecular mechanism involved in reducing the transvascular leakage and inflammation in rats under hypoxia."7.78Nifedipine inhibits hypoxia induced transvascular leakage through down regulation of NFkB. ( M, C; Mathew, T; P, H; S K S, S; S, S, 2012)
" The aim of the present study was to explore the effects of CPU0213, a dual endothelin ET(A)/ET(B) receptor antagonist, and nifedipine, a calcium antagonist, in relieving pulmonary hypertension (PH)."7.75CPU0213, a non-selective ETA/ETB receptor antagonist, improves pulmonary arteriolar remodeling of monocrotaline-induced pulmonary hypertension in rats. ( Cheng, YS; Cui, B; Dai, DZ; Dai, Y; Li, N; Zhang, TT, 2009)
"The effects of inhaled nitric oxide (NO) on hemodynamics and right ventricular (RV) contractility were compared with those of nitroprusside and nifedipine in 14 patients with severe chronic pulmonary hypertension."7.71Comparison of the effects of nitric oxide, nitroprusside, and nifedipine on hemodynamics and right ventricular contractility in patients with chronic pulmonary hypertension. ( Bigatello, LM; Cockrill, BA; Fifer, MA; Ginns, LC; Kacmarek, RM; Semigran, MJ; Zapol, WM, 2001)
"Acute hemodynamic effects of beraprost sodium were tested in a canine vasoconstrictive pulmonary hypertension model induced by the continuous infusion of U-46619, a thromboxane A(2)mimetic."7.71Comparative effects of beraprost, a stable analogue of prostacyclin, with PGE(1), nitroglycerin and nifedipine on canine model of vasoconstrictive pulmonary hypertension. ( Kurumatani, H; Matsushita, T; Tamura, M, 2001)
"In a young woman with primary pulmonary hypertension, treatment with low-dose nifedipine resulted in resolution of symptoms and of tricuspid regurgitation."7.70Rapid recurrence of pulmonary hypertension following cessation of nifedipine. ( Fennell, WH; Gallagher, MM; Hart, CM; Vaughan, CJ, 1998)
"The purpose of this study was to assess the utility of inhaled nitric oxide (NO), a selective pulmonary vasodilator, for predicting the safety and acute hemodynamic response to high-dose oral nifedipine in primary pulmonary hypertension (PPH)."7.70Inhaled nitric oxide in primary pulmonary hypertension: a safe and effective agent for predicting response to nifedipine. ( Knight, BP; Martinez, FJ; Ricciardi, MJ; Rubenfire, M, 1998)
" We wanted to determine whether nifedipine treatment prevents the increased pulmonary vascular resistance, blunted pulmonary vascular responses to acetylcholine, and reduced lung endothelial nitric oxide synthase (eNOS) amounts that we have found in a newborn model of chronic hypoxia-induced pulmonary hypertension."7.70Nifedipine inhibits pulmonary hypertension but does not prevent decreased lung eNOS in hypoxic newborn pigs. ( Fike, CD; Kaplowitz, MR, 1999)
"Experiments were carried on rats to study the preventive effects of calcium channel blockers Nitrendipine, Nifedipine and L-Arginine (L- Arginine is the physiological precursor of nitric oxide in endothelium-dependent relaxation) on chronic intermittent hypoxia induced pulmonary hypertension, on the right ventricular hypertrophy and pulmonary vascular pathologic changes."7.69[Comparative effects of calcium channel blockers and L-arginine on chronic intermittent hypoxic pulmonary hypertension in rats]. ( Chen, SC; Li, MR; Ma, G, 1994)
"In patients with primary pulmonary hypertension who respond to nifedipine during acute drug testing, there is a significant linear correlation of serum nifedipine concentration with pulmonary artery pressure and resistance."7.69Serum nifedipine concentrations and response of patients with pulmonary hypertension. ( Bauman, JL; Hoon, TJ; Phillips, BG; Rich, S; Schoen, MD; Schrader, BJ, 1996)
"Calcium channel blockers and adenosine have each been shown to be effective in reducing pulmonary artery pressure and pulmonary vascular resistance in patients with primary pulmonary hypertension."7.68Effects of adenosine in combination with calcium channel blockers in patients with primary pulmonary hypertension. ( Inbar, S; Kaufmann, E; Rich, S; Schrader, BJ; Vestal, RE, 1993)
"The present study was undertaken to evaluate at rest the short- and long-term effects of oral nifedipine (N) in patients with pulmonary hypertension (PH)."7.68Short- and long-term hemodynamic effects of oral nifedipine in patients with pulmonary hypertension secondary to COPD and lung fibrosis. Deleterious effects in patients with restrictive disease. ( Domenighetti, GM; Saglini, VG, 1992)
"The hemodynamic effects of intravenously administered adenosine, a potent vasodilator, were examined in 15 patients with pulmonary hypertension."7.68Comparison of the effects of adenosine and nifedipine in pulmonary hypertension. ( Inbar, S; Kaufmann, L; Rich, S; Schrader, BJ; Vestal, RE, 1992)
"We report the successful use of nifedipine in the treatment of acute pulmonary hypertension in an infant after a cardiac operation."7.68Successful treatment of acute postoperative pulmonary hypertension with nifedipine. ( Davis, DA; Russo, P, 1992)
"Ten patients with pulmonary hypertension associated with diffuse systemic sclerosis (1 patient), the CREST syndrome (calcinosis cutis, Reynaud's phenomenon, esophageal dysmotility, sclerodactyl, telangiectasia) (6 patients) and mixed connective tissue disease (3 patients) were studied to assess the effect of oral nifedipine on pulmonary and systemic hemodynamics."7.68Acute and long-term effects of nifedipine on pulmonary and systemic hemodynamics in patients with pulmonary hypertension associated with diffuse systemic sclerosis, the CREST syndrome and mixed connective tissue disease. ( Alpert, MA; Lambert, CR; Mukerji, B; Mukerji, V; Panayiotou, H; Pressly, TA; Sharp, GC, 1991)
"A 34-year-old man with primary pulmonary hypertension developed acute nonhemodynamic pulmonary edema after a loading dose of nifedipine."7.68Acute nonhemodynamic pulmonary edema with nifedipine in primary pulmonary hypertension. ( Decroly, P; Gottignies, P; Prigogine, T; Verhoeven, A; Waterlot, Y, 1991)
"To observe acute hemodynamic effects of pulmonary hypertension in chronic obstructive lung disease by nifedipine, we studied 16 patients with pulsed doppler ultrasound."7.68[Pulsed Doppler echocardiography assessment of acute hemodynamic effects of nifedipine on pulmonary hypertension in chronic obstructive lung disease]. ( Yuan, H, 1991)
"The pharmacokinetics and associated pharmacodynamics of nifedipine were studied in nine children aged 5 to 68 mo with bronchopulmonary dysplasia and pulmonary artery hypertension after a single oral dose of 1."7.68Pharmacokinetics and pharmacodynamics of nifedipine in children with bronchopulmonary dysplasia and pulmonary hypertension. ( Amidon, GL; Beekman, RH; Johnson, CE; Kostyshak, DA; Nguyen, T; Oh, DM, 1991)
"We evaluated the effects of the calcium channel blocker nifedipine (Nf) as a vasodilator compared with oxygen administration on pulmonary hypertension and right ventricular performance in 15 patients with COPD."7.68[Effects of nifedipine on pulmonary hypertension in patients with chronic obstructive pulmonary diseases--a comparison with oxygen administration]. ( Liu, Z; Yu, RJ, 1991)
"The effects of nifedipine in a single dose of 10 mg on the pulmonary circulation and the selected right and left ventricular function indices were studied in a group of 10 patients with secondary pulmonary hypertension (mean systolic pressure 55."7.68[Comparative study of acute and chronic effects of nifedipine in patients with secondary pulmonary hypertension]. ( Dubiel, JP; Królikowski, T; Mazurek, S; Nikodemowicz, M; Zmudka, K, 1991)
" Nifedipine depressed Qt significantly in this glass-bead embolization model of acute pulmonary hypertension."7.68Hemodynamic profiles of prostaglandin E1, isoproterenol, prostacyclin, and nifedipine in experimental porcine pulmonary hypertension. ( McLean, R; Pearl, RG; Prielipp, RC; Rosenthal, MH, 1991)
"The acute hemodynamic effects of both sublingual nifedipine (N) and intravenous hydralazine (Hy) were studied in 5 patients with primary pulmonary hypertension to ascertain whether the capacity for pulmonary vasodilatation was generalized or drug-specific, and to determine which of the 2 agents had preferential pulmonary vasodilatory effects."7.67Hemodynamic effects of nifedipine versus hydralazine in primary pulmonary hypertension. ( Borer, JS; Fisher, J; Goldberg, HL; Mermelstein, M; Moses, JW; Niarchos, AP; Whitman, HH, 1984)
"Two women with primary pulmonary hypertension were treated with felodipine, a vasodilating agent."7.67Felodipine in primary pulmonary hypertension. Report of two cases. ( Arnman, K; Rydén, L; Smedgård, P; Thorhallsson, E, 1984)
"The potential short-term pulmonary vasodilator effect of a calcium-channel blocker, nifedipine, was tested in seven patients with primary pulmonary hypertension."7.67Hemodynamic effects of nifedipine at rest and during exercise in primary pulmonary hypertension. ( Cohn, JN; Levine, TB; Olivari, MT; Weir, EK, 1984)
"A 23-year-old female with moderate primary pulmonary hypertension (PPH) was treated by chronic oral administration of long-acting prostaglandin-E1 (PGE1) and nifedipine."7.67[A case of primary pulmonary hypertension with beneficial effect of oral long-acting prostaglandin E1 and nifedipine]. ( Nagao, I; Ogawa, K; Oida, A; Tsukada, K; Yoshimura, M, 1989)
"The hemodynamic effects of nifedipine in 15 patients with pulmonary hypertension (PH) secondary to congenital heart disease (CHD) were evaluated."7.67[Therapeutic effects of nifedipine in pulmonary hypertension secondary to congenital heart disease]. ( Bai, YR; Chen, H; Wang, SZ, 1989)
"The acute effects of oxygen, nifedipine, and diltiazem were studied in eight patients with cystic fibrosis and mild pulmonary hypertension, to assess the possibility of relieving the latter before the occurrence of irreversible vascular changes."7.67Acute effects of oxygen, nifedipine, and diltiazem in patients with cystic fibrosis and mild pulmonary hypertension. ( Bossuyt, A; Dab, I; Davidson, A, 1989)
"The case of a 55-year-old woman with primary pulmonary hypertension is described who developed 2 hours after sublingual administration of a 10 mg capsule of nifedipine a severe rise in pulmonary arterial and right atrial pressures accompanied with dyspnoea and cyanosis."7.67Paradoxical elevation of pulmonary vascular resistance after nifedipine in primary pulmonary hypertension. A case study. ( Grad, A; Horvat, M; Mozina, M; Pohar, B; Rakovec, P, 1989)
"We evaluated in patients suffering from COPD-related pulmonary hypertension whether nifedipine therapy lowers acutely and chronically pulmonary vascular pressure and resistance and whether pulmonary transmural pressure may be further lowered by the combined use of nifedipine and oxygen."7.67Nifedipine reduces pulmonary pressure and vascular tone during short- but not long-term treatment of pulmonary hypertension in patients with chronic obstructive pulmonary disease. ( Agostoni, P; Doria, E; Galli, C; Guazzi, MD; Tamborini, G, 1989)
"We designed experiments to determine whether intermittent hypoxia would produce significant pathologic and physiologic changes in rats and whether pretreatment with a calcium channel blocker, nitrendipine, would reduce the pulmonary vascular remodeling and right ventricular hypertrophy caused by intermittent hypoxia."7.67Nitrendipine attenuates the pulmonary vascular remodeling and right ventricular hypertrophy caused by intermittent hypoxia in rats. ( Buescher, P; de la Monte, SM; Farrukh, I; Gottlieb, J; Gurtner, G; Hutchins, GM; Kennedy, TP; Lodato, R; Michael, JR; Rock, PC, 1986)
"Cardiovascular responses to the calcium antagonist nifedipine, alone and combined with low dose acetylsalicyclic acid (ASA), were evaluated in a piglet model of endotoxin-induced pulmonary hypertension."7.67The effect of nifedipine alone or combined with low dose acetylsalicyclic acid on endotoxin-induced pulmonary hypertension in the piglet. ( Huth, RG; Jüngst, BK; Schranz, D; Stopfkuchen, H, 1988)
"The effects of a single dose of nifedipine (20 mg sublingual) on the haemodynamics and parameters of tissue oxygenation were assessed by right heart catheterisation and oximetry of mixed arterial and venous blood in 24 patients with pulmonary hypertension secondary to severe chronic obstructive airways disease."7.67[Nifedipine in the treatment of chronic cor pulmonale]. ( Arnaud, A; Philip-Joet, F; Saadjian, A; Torresani, J; Tran N'guyen, A, 1986)
"In 41 patients with chronic obstructive pulmonary disease (COPD) and pulmonary hypertension, the effects of sublingual administration of 20 mg nifedipine and 0."7.67[Vasodilator therapy in pulmonary hypertension and chronic obstructive lung disease (COPD). Hemodynamic studies exemplified by nifedipine and nitroglycerin]. ( Fridrich, L; Gassner, A; Klicpera, M; Magometschnigg, D; Sommer, G, 1986)
"The acute hemodynamic effects of nifedipine were evaluated and compared to the effects of 95% oxygen in six children with bronchopulmonary dysplasia and pulmonary artery hypertension."7.67Acute hemodynamic effects of nifedipine in infants with bronchopulmonary dysplasia and pulmonary hypertension. ( Beekman, RH; Brownlee, JR; Rosenthal, A, 1988)
"To determine whether Nifedipine reduces pulmonary artery pressure and pulmonary vascular resistance in patients with hypoxic pulmonary hypertension, we have studied ten clinically stable patients with chronic obstructive airways disease following acute administration of sublingual Nifedipine 20 mg and also after three months long term treatment with Nifedipine tablets 20mg bd."7.67Acute and long term effect of nifedipine on pulmonary hypertension secondary to chronic obstructive airways disease. ( Cunnington, AR; Johnson, DC; Joshi, RC; Mehta, R, 1986)
"The effects of a single dose of nifedipine (20 mg sublingually) on hemodynamics and tissue oxygenation were evaluated in 24 patients suffering from pulmonary hypertension secondary to severe chronic obstructive lung disease."7.67Hemodynamic and oxygen delivery responses to nifedipine in pulmonary hypertension secondary to chronic obstructive lung disease. ( Arnaud, A; Philip-Joet, F; Saadjian, A, 1987)
"To detect whether pulmonary vascular responsiveness is a factor which can aggravate the pulmonary hypertension induced by irreversible pulmonary fibrosis, we examined the acute hemodynamic effects of low-flow oxygen and of nifedipine both at rest and during exercise in 8 patients with idiopathic pulmonary fibrosis (IPF)."7.67Pulmonary vascular responsiveness at rest and during exercise in idiopathic pulmonary fibrosis: effects of oxygen and nifedipine. ( Galavotti, V; Gunella, G; Papiris, S; Sturani, C, 1986)
"The favourable effect of long-term (36 months) treatment with nifedipine in a case of primary pulmonary hypertension is described."7.67Long-term favourable effect of nifedipine in primary pulmonary hypertension. Report of a case with hemodynamic evaluation after 3 and after 16 months and with clinical follow-up during 36 months. ( Di Donato, M; Musante, R, 1985)
"We evaluated the hemodynamic effects of the calcium antagonist nifedipine in 13 consecutive patients admitted to the intensive care unit with secondary pulmonary hypertension."7.67Hemodynamic effects of nifedipine on secondary pulmonary hypertension in man. ( Carlier, J; Cremers, S; D'Orio, V; el Allaf, D; Garzaniti, N; Marcelle, R, 1985)
"In 10 patients with advanced chronic lung disease and pulmonary hypertension central haemodynamics and pulmonary gas exchange were studied at rest and during exercise, before and during continuous infusion of the calcium antagonist felodipine, which lowers vascular resistance by selective action on vascular smooth muscle."7.67The effect of a new calcium antagonist, felodipine, on pulmonary hypertension and gas exchange in chronic obstructive lung disease. ( Bratel, T; Hedenstierna, G; Nyquist, O; Ripe, E, 1985)
"The effects of nifedipine on hemodynamics and blood gases were studied in 10 patients with pulmonary hypertension secondary to chronic obstructive lung disease."7.67Two-week nifedipine treatment for pulmonary hypertension complicating chronic obstructive lung disease. ( Arnaud, A; Guintoli, A; Philip-Joet, F; Saadjian, A; Torresani, J, 1985)
"A 64-year-old woman with systemic sclerosis and pulmonary hypertension underwent Swan-Ganz catheterization to test her response to the calcium channel blocker nifedipine."7.67Transient effect of nifedipine on pulmonary hypertension of systemic sclerosis. ( Fudman, EJ; Kelling, DG, 1985)
"To evaluate the potential value of nifedipine treatment for primary pulmonary hypertension, hemodynamic and scintigraphic measurements were made before and 15 to 30 minutes after nifedipine, 10 to 20 mg, was given sublingually to nine patients."7.66Treatment of primary pulmonary hypertension with nifedipine. A hemodynamic and scintigraphic evaluation. ( Firth, BG; Hillis, LD; Nicod, P; Rubin, LJ, 1983)
"The effects of 3 types of vasoactive agents, hydralazine, nifedipine and amrinone, were evaluated in 7 patients with primary pulmonary hypertension (PPH)."7.66Comparative actions of hydralazine, nifedipine and amrinone in primary pulmonary hypertension. ( Ganz, R; Levy, PS; Rich, S, 1983)
"The effect of sublingual nifedipine (20 mg) on haemodynamics at rest and during bicycle ergometry in supine position was assessed in 22 patients with precapillary pulmonary hypertension (obstructive form: n = 17, restrictive form: n = 2, combined obstructive-restrictive: n = 3)."7.66[Effect of nifedipine on hemodynamics in precapillary pulmonary hypertension at rest and during exertion]. ( Fridrich, L; Gassner, A; Lenz, K; Pichler, M; Sykora, J; Tizek, H, 1983)
"The effects of nifedipine on hemodynamics and pulmonary gas exchange were investigated in two patients with primary pulmonary hypertension."7.66Effects of nifedipine on ventilation/perfusion matching in primary pulmonary hypertension. ( Denolin, H; Mélot, C; Mols, P; Naeije, R; Vandenbossche, JL, 1983)
"Progressive dyspnea and syncope occurred in a young woman with primary pulmonary hypertension despite therapy with hydralazine."7.66Hemodynamic effects of nifedipine in primary pulmonary hypertension. ( Douglas, JS, 1983)
"In a 22-year-old woman with primary pulmonary hypertension resistant to all previous attempts to reduce the pulmonary vascular resistance, there was dramatic improvement after the first dose of nifedipine, 20 mg po, which was not sustained with subsequent doses."7.66Rapid attenuation of response to nifedipine in primary pulmonary hypertension. ( Fennell, WH; Luck, JC; Tortoledo, F; Wood, BA, 1982)
"The advantages of long-term administration of vasodilators in the treatment of chronic cor pulmonale were investigated after informed consent in 60 patients with obstructive respiratory insufficiency (56 men, 4 women, mean age 63."6.66One-year clinical study on nifedipine in the treatment of pulmonary hypertension in chronic obstructive lung disease. ( Arnaud, A; Philip-Joet, F; Saadjian, A; Surpas, P; Vestri, R, 1988)
"Myocyte apoptosis and muscle atrophy were significantly decreased with irbesartan compared with untreated CHF rats."5.31Beneficial effects on skeletal muscle of the angiotensin II type 1 receptor blocker irbesartan in experimental heart failure. ( Angelini, A; Battista Ambrosio, G; Dalla Libera, L; Ravara, B; Rossini, K; Sandri, M; Thiene, G; Vescovo, G, 2001)
"Nifedipine was administered in 20 mg doses hourly during right cardiac catheterization and was repeated after 1 hour until a decrease in systemic pressure occurred."5.29[Effect of large doses of nifedipine on pulmonary hypertension in patients with recurrent pulmonary thromboembolism]. ( Fijałkowska, A; Filipecki, S; Hajduk, B; Pałasiewicz, G; Polowiec, Z; Radomyski, A; Tomkowski, W, 1994)
"Nifedipine (10 mg/kg) was administered intraperitoneally every day."5.29The effect of nifedipine on monocrotaline-induced pulmonary hypertension in rats. ( Harada, Y; Inoue, M; Mori, C; Tanaka, O; Watanabe, K, 1993)
"Nifedipine was discontinued after 8 months due to lack of improvement in the patient's state."5.28[Treatment of primary pulmonary hypertension with high doses of nifedipine controlled by Doppler echocardiography]. ( Filipecki, S; Pasierski, T; Radomyski, A; Tomkowski, W; Torbicki, A, 1991)
" Under this aspect we examined 44 patients by right heart catheterisation at rest and at exercise before and after sublingual application of a single dose of 20 mg nifedipine (Corinfar) as well as under continuous dosage of 30-60 mg daily."5.28The influence of nifedipine (Corinfar) on pulmonary hypertension in chronic obstructive lung disease. ( Evers, H; Harzbecker, K; Orschekowski, H; Schauer, J; Schilling, W; Steiniger, L; Winkler, J, 1990)
"Pulmonary hypertension was produced by continuous intravenous administration of U46619 to halothane-anesthetized sheep."5.28Hemodynamic effects of diltiazem during vasoconstrictor pulmonary hypertension in sheep. ( Finn, JC; Pearl, RG, 1990)
"Nifedipine was found to be the most effective."5.28[A case of primary pulmonary hypertension with high venous thromboxane B2 concentration]. ( Abe, S; Kawakami, Y; Kishi, F; Miyamoto, K; Nagata, H; Nakano, T; Suzuki, A; Takahashi, S; Takai, S, 1990)
" During 12 weeks of prednisone treatment in a dosage of 40 mg daily, her condition markedly deteriorated clinically and hemodynamically as manifested by pulmonary artery pressure (PAP), pulmonary vascular resistance (PVR), cardiac output (CO), mixed venous O2 saturation, and systemic vascular resistance (SVR)."5.28Nifedipine and prazosin in the management of pulmonary hypertension in CREST syndrome. ( Dresner-Feigin, R; Galun, E; Glikson, M; Pollack, A; Rubinow, A, 1990)
"Primary pulmonary hypertension is a disease of unknown etiology."5.28[Nifedipine in primary pulmonary hypertension while waiting for heart-lung transplantation]. ( Petersen, TI; Svanegård, J; Thayssen, P, 1989)
"Nifedipine was then administered sublingually in a dose of 1 mg/kg and produced an immediate and dramatic improvement in the right radial artery pO2 that was sustained despite persistence of the right-to-left shunt."5.28[Efficacy of nifedipine on refractory hypoxemia associated with diaphragmatic hernia in the newborn infant. Apropos of a case]. ( Burguet, A; Destuynder, R; Fromentin, C; Menget, A, 1989)
"Nifedipine is a calcium antagonistic drug which reduces elevated vascular resistances."5.26Hemodynamic effects of nifedipine in pulmonary hypertension. ( Camerini, F; Fioretti, P; Klugmann, S; Salvi, A, 1982)
"This study was designed to determine whether calcium antagonists, diltiazem and nifedipine, can depress low temperature-induced pulmonary hypertension (PH) in broilers (also known as ascites) and to characterize their efficacy on hemodynamics and pulmonary artery function."5.14Calcium antagonists, diltiazem and nifedipine, protect broilers against low temperature-induced pulmonary hypertension and pulmonary vascular remodeling. ( Gao, M; Guo, Y; Qiao, J; Yang, Y, 2010)
" Long-term therapy with aerosolized iloprost (long-acting PGI(2) analog) resulted in unequivocal clinical improvement from a state of immobilization and severe resting dyspnea in a patient with decompensated right heart failure."5.09Inhaled prostacyclin and iloprost in severe pulmonary hypertension secondary to lung fibrosis. ( Ghofrani, HA; Grimminger, F; Olschewski, H; Schermuly, R; Seeger, W; Temmesfeld-Wollbruck, B; Walmrath, D, 1999)
"The clinical course in primary pulmonary hypertension (PPH) is improved by calcium channel blocker therapy in those with a favorable hemodynamic response during a trial of high-dose oral nifedipine."5.09Echocardiographic predictors of an adverse response to a nifedipine trial in primary pulmonary hypertension: diminished left ventricular size and leftward ventricular septal bowing. ( Armstrong, WF; Bach, DS; Bossone, E; Ricciardi, MJ; Rubenfire, M, 1999)
"To assess changes in physiologic shunting and oxygenation following short-term treatment with nifedipine in patients with pulmonary hypertension secondary to chronic obstructive pulmonary disease."5.07Effect of nifedipine on physiologic shunting and oxygenation in chronic obstructive pulmonary disease. ( Bone, MF; Kalra, L, 1993)
"Detailed examination of hemodynamics in patients with portal and pulmonary hypertension was performed upon acute drug tests and course administration of nitrosorbide++, corinfar and propranolol."5.07[Drug therapy of pulmonary and portal hypertension in liver cirrhosis]. ( Andreev, NG; Maev, IV; Vorob'ev, LP, 1991)
"The objective of this study was to evaluate the long-term results of an 18 months nifedipine treatment in patients with pulmonary hypertension (PHT) secondary to chronic obstructive broncho-pulmonary disease (COBPD)."5.06[Long-term treatment of pulmonary hypertension in chronic obstructive bronchopneumopathies with nifedipine. Hemodynamic study over 18 months]. ( Arnaud, A; Philip-Joet, F; Saadjian, A; Vestri, R, 1989)
"A two-year-old child dying of pulmonary hypertension and cor pulmonale secondary to bronchopulmonary dysplasia, was demonstrated to have reactive pulmonary hypertension in response to 100% oxygen and isoproterenol infusion."5.06Treatment of pulmonary hypertension with diltiazem in a child with bronchopulmonary dysplasia. ( Bingham, WT; Duncan, WJ; Kasian, GF; Mersal, A; Ninan, A; Sankaran, K; Tyrrell, MJ, 1988)
" A patient is described who had POEMS syndrome with precapillary pulmonary hypertension and Raynaud's phenomenon, and who responded well to a short course of corticosteroids and long term nifedipine."4.80Reversible pulmonary hypertension in POEMS syndrome--another etiology of triggered pulmonary vasculopathy? ( Bossone, E; Erba, H; Paciocco, G; Rubenfire, M, 2000)
"Meta-analysis of the trials of nifedipine therapy in patients with pulmonary hypertension demonstrated a decrease in pulmonary artery pressure that was associated with an amelioration of clinical symptoms."4.79Meta-analysis of the long-term effect of nifedipine for pulmonary hypertension. ( Lehrman, S; Malik, AS; Warshafsky, S, 1997)
" Verapamil is extremely effective in patients with supraventricular tachyarrhythmias, hypertrophic cardiomyopathy, and the various anginal syndromes, but it appears to be ineffective or possibly even deleterious in those with pulmonary hypertension, congestive heart failure of any cause, and Raynaud's phenomenon or disease."4.77Calcium antagonists in patients with cardiovascular disease. Current perspectives. ( Hillis, LD; Winniford, MD, 1985)
" Biochemical evidence suggests that pulmonary vasoconstriction results from the transmembrane flux of calcium into vascular smooth muscle; accordingly, the pulmonary pressor responses in experimental hypoxic pulmonary hypertension can be attenuated by verapamil and nifedipine."4.77Therapeutic application of calcium-channel antagonists for pulmonary hypertension. ( Packer, M, 1985)
"The dihydropyridine derivatives increase [Ca(2+)](cyt) by potentiating the activity of CaSR in PASMC independently of their blocking (or activating) effect on Ca(2+) channels; therefore, it is possible that the use of dihydropyridine Ca(2+) channel blockers (eg, nifedipine) to treat IPAH patients with upregulated CaSR in PASMC may exacerbate pulmonary hypertension."3.79Dihydropyridine Ca(2+) channel blockers increase cytosolic [Ca(2+)] by activating Ca(2+)-sensing receptors in pulmonary arterial smooth muscle cells. ( Guo, Q; Ko, EA; Makino, A; Pohl, NM; Smith, KA; Song, S; Wan, J; Yamamura, A; Yamamura, H; Yuan, JX; Zeifman, A; Zimnicka, AM, 2013)
"We have studied the prophylactic administration of nifedipine and its molecular mechanism involved in reducing the transvascular leakage and inflammation in rats under hypoxia."3.78Nifedipine inhibits hypoxia induced transvascular leakage through down regulation of NFkB. ( M, C; Mathew, T; P, H; S K S, S; S, S, 2012)
" The aim of the present study was to explore the effects of CPU0213, a dual endothelin ET(A)/ET(B) receptor antagonist, and nifedipine, a calcium antagonist, in relieving pulmonary hypertension (PH)."3.75CPU0213, a non-selective ETA/ETB receptor antagonist, improves pulmonary arteriolar remodeling of monocrotaline-induced pulmonary hypertension in rats. ( Cheng, YS; Cui, B; Dai, DZ; Dai, Y; Li, N; Zhang, TT, 2009)
" Male Sprague-dawley Rats (220 +/- 20 G) Were Divided Into Four Groups: (I) Control; (Ii) Untreated Hypoxic (28 Days Hypoxia); (Iii) Hypoxic Rats Treated In The Last 5 Days Of Hypoxia With Nifedipine(5 Mg/kg Per Day, P."3.73CPU0507, an endothelin receptor antagonist, improves rat hypoxic pulmonary artery hypertension and constriction in vivo and in vitro. ( Dai, DZ; Dai, Y; Guan, L; Ji, M; Yuan, SH, 2006)
"Both of aminophylline and nifedipine can attenuate pulmonary hypertension in patients with HAPE, but the effect of aminophylline was better than the effect of nifedipine."3.72[Hemodynamic effects of aminophylline and nifedipine in patients with high altitude pulmonary edema]. ( Cheng, GL; Gao, YQ; Li, SZ; Liou, FY; Mou, XB; Tang, HY; Ye, GL; Zhou, XB, 2004)
"The effects of inhaled nitric oxide (NO) on hemodynamics and right ventricular (RV) contractility were compared with those of nitroprusside and nifedipine in 14 patients with severe chronic pulmonary hypertension."3.71Comparison of the effects of nitric oxide, nitroprusside, and nifedipine on hemodynamics and right ventricular contractility in patients with chronic pulmonary hypertension. ( Bigatello, LM; Cockrill, BA; Fifer, MA; Ginns, LC; Kacmarek, RM; Semigran, MJ; Zapol, WM, 2001)
"Acute hemodynamic effects of beraprost sodium were tested in a canine vasoconstrictive pulmonary hypertension model induced by the continuous infusion of U-46619, a thromboxane A(2)mimetic."3.71Comparative effects of beraprost, a stable analogue of prostacyclin, with PGE(1), nitroglycerin and nifedipine on canine model of vasoconstrictive pulmonary hypertension. ( Kurumatani, H; Matsushita, T; Tamura, M, 2001)
"In a young woman with primary pulmonary hypertension, treatment with low-dose nifedipine resulted in resolution of symptoms and of tricuspid regurgitation."3.70Rapid recurrence of pulmonary hypertension following cessation of nifedipine. ( Fennell, WH; Gallagher, MM; Hart, CM; Vaughan, CJ, 1998)
"The purpose of this study was to assess the utility of inhaled nitric oxide (NO), a selective pulmonary vasodilator, for predicting the safety and acute hemodynamic response to high-dose oral nifedipine in primary pulmonary hypertension (PPH)."3.70Inhaled nitric oxide in primary pulmonary hypertension: a safe and effective agent for predicting response to nifedipine. ( Knight, BP; Martinez, FJ; Ricciardi, MJ; Rubenfire, M, 1998)
"To describe the clinical course of pregnancies complicated by pulmonary hypertension and treated with the pulmonary vasodilators nifedipine and prostacyclin."3.70Pulmonary hypertension in pregnancy: treatment with pulmonary vasodilators. ( Easterling, TR; Ralph, DD; Schmucker, BC, 1999)
" We wanted to determine whether nifedipine treatment prevents the increased pulmonary vascular resistance, blunted pulmonary vascular responses to acetylcholine, and reduced lung endothelial nitric oxide synthase (eNOS) amounts that we have found in a newborn model of chronic hypoxia-induced pulmonary hypertension."3.70Nifedipine inhibits pulmonary hypertension but does not prevent decreased lung eNOS in hypoxic newborn pigs. ( Fike, CD; Kaplowitz, MR, 1999)
" Rats were exposed to 3 wk of normoxia, hypoxia (10% O2), or monocrotaline (MCT; single dose = 60 mg/kg) and treated with either nothing (control), inhaled NO (20 ppm), or nifedipine (10 mg x kg(-1) x day(-1)."3.70Inhaled nitric oxide and nifedipine have similar effects on lung cGMP levels in rats. ( Frank, DU; Horstman, DJ; McCall, DA; Rich, GF, 1999)
" infusion of U46619, a thromboxane A2 (TXA2) mimic, or by alveolar hypoxia."3.69HA1004, an intracellular calcium antagonist, selectively attenuates pulmonary hypertension in newborn lambs. ( Crowley, MR; Fineman, JR; Soifer, SJ, 1994)
"Experiments were carried on rats to study the preventive effects of calcium channel blockers Nitrendipine, Nifedipine and L-Arginine (L- Arginine is the physiological precursor of nitric oxide in endothelium-dependent relaxation) on chronic intermittent hypoxia induced pulmonary hypertension, on the right ventricular hypertrophy and pulmonary vascular pathologic changes."3.69[Comparative effects of calcium channel blockers and L-arginine on chronic intermittent hypoxic pulmonary hypertension in rats]. ( Chen, SC; Li, MR; Ma, G, 1994)
"In patients with primary pulmonary hypertension who respond to nifedipine during acute drug testing, there is a significant linear correlation of serum nifedipine concentration with pulmonary artery pressure and resistance."3.69Serum nifedipine concentrations and response of patients with pulmonary hypertension. ( Bauman, JL; Hoon, TJ; Phillips, BG; Rich, S; Schoen, MD; Schrader, BJ, 1996)
"NO inhalation can accurately predict a vasodilator response to nifedipine in patients with severe pulmonary hypertension without adverse effects on systemic haemodynamics and gas exchange."3.69Nitric oxide and prostacyclin as test agents of vasoreactivity in severe precapillary pulmonary hypertension: predictive ability and consequences on haemodynamics and gas exchange. ( Bulpa, P; Chevrolet, JC; Jolliet, P; Ritz, M; Thorens, JB, 1997)
"Calcium channel blockers and adenosine have each been shown to be effective in reducing pulmonary artery pressure and pulmonary vascular resistance in patients with primary pulmonary hypertension."3.68Effects of adenosine in combination with calcium channel blockers in patients with primary pulmonary hypertension. ( Inbar, S; Kaufmann, E; Rich, S; Schrader, BJ; Vestal, RE, 1993)
"The present study was undertaken to evaluate at rest the short- and long-term effects of oral nifedipine (N) in patients with pulmonary hypertension (PH)."3.68Short- and long-term hemodynamic effects of oral nifedipine in patients with pulmonary hypertension secondary to COPD and lung fibrosis. Deleterious effects in patients with restrictive disease. ( Domenighetti, GM; Saglini, VG, 1992)
"The hemodynamic effects of intravenously administered adenosine, a potent vasodilator, were examined in 15 patients with pulmonary hypertension."3.68Comparison of the effects of adenosine and nifedipine in pulmonary hypertension. ( Inbar, S; Kaufmann, L; Rich, S; Schrader, BJ; Vestal, RE, 1992)
"We report the successful use of nifedipine in the treatment of acute pulmonary hypertension in an infant after a cardiac operation."3.68Successful treatment of acute postoperative pulmonary hypertension with nifedipine. ( Davis, DA; Russo, P, 1992)
"Ten patients with pulmonary hypertension associated with diffuse systemic sclerosis (1 patient), the CREST syndrome (calcinosis cutis, Reynaud's phenomenon, esophageal dysmotility, sclerodactyl, telangiectasia) (6 patients) and mixed connective tissue disease (3 patients) were studied to assess the effect of oral nifedipine on pulmonary and systemic hemodynamics."3.68Acute and long-term effects of nifedipine on pulmonary and systemic hemodynamics in patients with pulmonary hypertension associated with diffuse systemic sclerosis, the CREST syndrome and mixed connective tissue disease. ( Alpert, MA; Lambert, CR; Mukerji, B; Mukerji, V; Panayiotou, H; Pressly, TA; Sharp, GC, 1991)
"A 34-year-old man with primary pulmonary hypertension developed acute nonhemodynamic pulmonary edema after a loading dose of nifedipine."3.68Acute nonhemodynamic pulmonary edema with nifedipine in primary pulmonary hypertension. ( Decroly, P; Gottignies, P; Prigogine, T; Verhoeven, A; Waterlot, Y, 1991)
"To observe acute hemodynamic effects of pulmonary hypertension in chronic obstructive lung disease by nifedipine, we studied 16 patients with pulsed doppler ultrasound."3.68[Pulsed Doppler echocardiography assessment of acute hemodynamic effects of nifedipine on pulmonary hypertension in chronic obstructive lung disease]. ( Yuan, H, 1991)
"The pharmacokinetics and associated pharmacodynamics of nifedipine were studied in nine children aged 5 to 68 mo with bronchopulmonary dysplasia and pulmonary artery hypertension after a single oral dose of 1."3.68Pharmacokinetics and pharmacodynamics of nifedipine in children with bronchopulmonary dysplasia and pulmonary hypertension. ( Amidon, GL; Beekman, RH; Johnson, CE; Kostyshak, DA; Nguyen, T; Oh, DM, 1991)
"We evaluated the effects of the calcium channel blocker nifedipine (Nf) as a vasodilator compared with oxygen administration on pulmonary hypertension and right ventricular performance in 15 patients with COPD."3.68[Effects of nifedipine on pulmonary hypertension in patients with chronic obstructive pulmonary diseases--a comparison with oxygen administration]. ( Liu, Z; Yu, RJ, 1991)
"Forty-seven patients with primary pulmonary hypertension were evaluated with a dose titration protocol utilizing nifedipine (20 mg orally) or diltiazem (60 mg orally) given every hour until maximal effectiveness was achieved."3.68High dose titration of calcium channel blocking agents for primary pulmonary hypertension: guidelines for short-term drug testing. ( Kaufmann, E; Rich, S, 1991)
"The effects of nifedipine in a single dose of 10 mg on the pulmonary circulation and the selected right and left ventricular function indices were studied in a group of 10 patients with secondary pulmonary hypertension (mean systolic pressure 55."3.68[Comparative study of acute and chronic effects of nifedipine in patients with secondary pulmonary hypertension]. ( Dubiel, JP; Królikowski, T; Mazurek, S; Nikodemowicz, M; Zmudka, K, 1991)
" Nifedipine depressed Qt significantly in this glass-bead embolization model of acute pulmonary hypertension."3.68Hemodynamic profiles of prostaglandin E1, isoproterenol, prostacyclin, and nifedipine in experimental porcine pulmonary hypertension. ( McLean, R; Pearl, RG; Prielipp, RC; Rosenthal, MH, 1991)
"The acute hemodynamic effects of both sublingual nifedipine (N) and intravenous hydralazine (Hy) were studied in 5 patients with primary pulmonary hypertension to ascertain whether the capacity for pulmonary vasodilatation was generalized or drug-specific, and to determine which of the 2 agents had preferential pulmonary vasodilatory effects."3.67Hemodynamic effects of nifedipine versus hydralazine in primary pulmonary hypertension. ( Borer, JS; Fisher, J; Goldberg, HL; Mermelstein, M; Moses, JW; Niarchos, AP; Whitman, HH, 1984)
"The hemodynamic and clinical responses to calcium channel blockade with verapamil and nifedipine were compared with those of hydralazine in 12 patients with pulmonary hypertension secondary to obliterative pulmonary vascular disease."3.67Adverse hemodynamic and clinical effects of calcium channel blockade in pulmonary hypertension secondary to obliterative pulmonary vascular disease. ( Medina, N; Packer, M; Yushak, M, 1984)
"Cardiovascular responses to the calcium antagonists verapamil and nifedipine were evaluated in a piglet model of hypoxic pulmonary hypertension."3.67The effect of calcium antagonists on hypoxic pulmonary hypertension in the piglet. ( Bancalari, E; Dickstein, PJ; Goldberg, RN; Trindade, O, 1984)
"To determine whether nifedipine reduces pulmonary artery pressure and pulmonary vascular resistance index during rest and exercise in patients with hypoxic pulmonary hypertension, we studied 6 clinically stable patients using a randomized, double-blind, crossover design."3.67Nifedipine inhibits hypoxic pulmonary vasoconstriction during rest and exercise in patients with chronic obstructive pulmonary disease. A controlled double-blind study. ( Huang, CK; Kallman, CH; Kennedy, TP; Michael, JR; Schlott, W; Summer, W; Zahka, K, 1984)
"Two women with primary pulmonary hypertension were treated with felodipine, a vasodilating agent."3.67Felodipine in primary pulmonary hypertension. Report of two cases. ( Arnman, K; Rydén, L; Smedgård, P; Thorhallsson, E, 1984)
"The potential short-term pulmonary vasodilator effect of a calcium-channel blocker, nifedipine, was tested in seven patients with primary pulmonary hypertension."3.67Hemodynamic effects of nifedipine at rest and during exercise in primary pulmonary hypertension. ( Cohn, JN; Levine, TB; Olivari, MT; Weir, EK, 1984)
"Catheterization of the pulmonary artery and radiocirculography were used in 30 patients with chronic bronchitis (CB) in order to study changes in hemodynamics induced by intravenous injections of 5 and 10 mg verapamil or by 4-5 weeks of the treatment with finoptin and corinfar."3.67[The effect of calcium antagonists on pulmonary hemodynamics in patients with chronic bronchitis with manifest and latent pulmonary hypertension]. ( Volkova, LI, 1989)
"A 23-year-old female with moderate primary pulmonary hypertension (PPH) was treated by chronic oral administration of long-acting prostaglandin-E1 (PGE1) and nifedipine."3.67[A case of primary pulmonary hypertension with beneficial effect of oral long-acting prostaglandin E1 and nifedipine]. ( Nagao, I; Ogawa, K; Oida, A; Tsukada, K; Yoshimura, M, 1989)
"The hemodynamic effects of nifedipine in 15 patients with pulmonary hypertension (PH) secondary to congenital heart disease (CHD) were evaluated."3.67[Therapeutic effects of nifedipine in pulmonary hypertension secondary to congenital heart disease]. ( Bai, YR; Chen, H; Wang, SZ, 1989)
"The acute effects of oxygen, nifedipine, and diltiazem were studied in eight patients with cystic fibrosis and mild pulmonary hypertension, to assess the possibility of relieving the latter before the occurrence of irreversible vascular changes."3.67Acute effects of oxygen, nifedipine, and diltiazem in patients with cystic fibrosis and mild pulmonary hypertension. ( Bossuyt, A; Dab, I; Davidson, A, 1989)
"We studied the simultaneous effects of nifedipine on the pulmonary circulation and blood gases in 12 patients with pulmonary hypertension secondary to obstructive chronic bronchitis."3.67[Value of nifedipine in respiratory failure related to obstructive chronic bronchitis during treatment over 6 months]. ( Boita, F; Boutaud, P; Herpin, D; Ingrand, P; Meurice, JC; Patte, F; Underner, M, 1989)
"The case of a 55-year-old woman with primary pulmonary hypertension is described who developed 2 hours after sublingual administration of a 10 mg capsule of nifedipine a severe rise in pulmonary arterial and right atrial pressures accompanied with dyspnoea and cyanosis."3.67Paradoxical elevation of pulmonary vascular resistance after nifedipine in primary pulmonary hypertension. A case study. ( Grad, A; Horvat, M; Mozina, M; Pohar, B; Rakovec, P, 1989)
"To evaluate pulmonary vasoreactivity in children and young adults with primary pulmonary hypertension, we performed cardiac catheterizations on nine patients with primary pulmonary hypertension (nine months to 23 years old) and made hemodynamic measurements: before and after infusing prostacyclin, and before and after administering sublingual nifedipine."3.67Pharmacologically induced pulmonary vasodilatation in children and young adults with primary pulmonary hypertension. ( Barst, RJ, 1986)
"We evaluated in patients suffering from COPD-related pulmonary hypertension whether nifedipine therapy lowers acutely and chronically pulmonary vascular pressure and resistance and whether pulmonary transmural pressure may be further lowered by the combined use of nifedipine and oxygen."3.67Nifedipine reduces pulmonary pressure and vascular tone during short- but not long-term treatment of pulmonary hypertension in patients with chronic obstructive pulmonary disease. ( Agostoni, P; Doria, E; Galli, C; Guazzi, MD; Tamborini, G, 1989)
"We designed experiments to determine whether intermittent hypoxia would produce significant pathologic and physiologic changes in rats and whether pretreatment with a calcium channel blocker, nitrendipine, would reduce the pulmonary vascular remodeling and right ventricular hypertrophy caused by intermittent hypoxia."3.67Nitrendipine attenuates the pulmonary vascular remodeling and right ventricular hypertrophy caused by intermittent hypoxia in rats. ( Buescher, P; de la Monte, SM; Farrukh, I; Gottlieb, J; Gurtner, G; Hutchins, GM; Kennedy, TP; Lodato, R; Michael, JR; Rock, PC, 1986)
"Cardiovascular responses to the calcium antagonist nifedipine, alone and combined with low dose acetylsalicyclic acid (ASA), were evaluated in a piglet model of endotoxin-induced pulmonary hypertension."3.67The effect of nifedipine alone or combined with low dose acetylsalicyclic acid on endotoxin-induced pulmonary hypertension in the piglet. ( Huth, RG; Jüngst, BK; Schranz, D; Stopfkuchen, H, 1988)
"The effects of a single dose of nifedipine (20 mg sublingual) on the haemodynamics and parameters of tissue oxygenation were assessed by right heart catheterisation and oximetry of mixed arterial and venous blood in 24 patients with pulmonary hypertension secondary to severe chronic obstructive airways disease."3.67[Nifedipine in the treatment of chronic cor pulmonale]. ( Arnaud, A; Philip-Joet, F; Saadjian, A; Torresani, J; Tran N'guyen, A, 1986)
"In 41 patients with chronic obstructive pulmonary disease (COPD) and pulmonary hypertension, the effects of sublingual administration of 20 mg nifedipine and 0."3.67[Vasodilator therapy in pulmonary hypertension and chronic obstructive lung disease (COPD). Hemodynamic studies exemplified by nifedipine and nitroglycerin]. ( Fridrich, L; Gassner, A; Klicpera, M; Magometschnigg, D; Sommer, G, 1986)
"The acute hemodynamic effects of nifedipine were evaluated and compared to the effects of 95% oxygen in six children with bronchopulmonary dysplasia and pulmonary artery hypertension."3.67Acute hemodynamic effects of nifedipine in infants with bronchopulmonary dysplasia and pulmonary hypertension. ( Beekman, RH; Brownlee, JR; Rosenthal, A, 1988)
" Cardiac catheterization revealed a primary pulmonary hypertension sensible to nifedipine, but after the initial favourable results the clinical course rapidly went down and the child died from right sided congestive heart failure."3.67Unexplained plexogenic pulmonary arteriopathy: an unusual rapidly progressive case in childhood. ( Ammirati, A; Coli, A; Dina, MA, 1988)
"The haemodynamic effects of nifedipine were studied in 14 patients (aged 8-14 years, seven male and seven female) with ventricular septal defect with and without pulmonary hypertension."3.67Acute haemodynamic effects of nifedipine in patients with ventricular septal defect. ( Berisha, S; Frasheri, A; Goda, A; Kastrati, A; Popa, Y, 1988)
"To determine whether Nifedipine reduces pulmonary artery pressure and pulmonary vascular resistance in patients with hypoxic pulmonary hypertension, we have studied ten clinically stable patients with chronic obstructive airways disease following acute administration of sublingual Nifedipine 20 mg and also after three months long term treatment with Nifedipine tablets 20mg bd."3.67Acute and long term effect of nifedipine on pulmonary hypertension secondary to chronic obstructive airways disease. ( Cunnington, AR; Johnson, DC; Joshi, RC; Mehta, R, 1986)
" We evaluated the acute and chronic (three months) effects of the thromboxane synthetase inhibitor CGS13080 administered 200 mg every six hours on the resting hemodynamics in ten patients with primary pulmonary hypertension (PPH), and on their response to 20 mg of nifedipine given sublingually before and after the thromboxane synthetase inhibitor treatment."3.67Thromboxane synthetase inhibition in primary pulmonary hypertension. ( Brundage, BH; Hart, K; Kieras, K; Rich, S, 1987)
"The effects of a single dose of nifedipine (20 mg sublingually) on hemodynamics and tissue oxygenation were evaluated in 24 patients suffering from pulmonary hypertension secondary to severe chronic obstructive lung disease."3.67Hemodynamic and oxygen delivery responses to nifedipine in pulmonary hypertension secondary to chronic obstructive lung disease. ( Arnaud, A; Philip-Joet, F; Saadjian, A, 1987)
"We used an improved noninvasive radionuclide method, recently developed by us, to evaluate changes in pulmonary artery pressure induced by sublingual nifedipine in patients with chronic obstructive pulmonary disease and pulmonary hypertension."3.67The value of right atrial emptying rate in predicting reduction in pulmonary artery pressure in patients with chronic obstructive pulmonary disease. ( Frankel, A; Marmor, AT; Michaeli, S; Plich, M; Schneeweiss, A, 1987)
"We studied (via acute vasodilator testing with nifedipine) 27 patients with pulmonary arterial hypertension (PAH) (11 primary, 16 secondary PAH, [including six patients with Raynaud's phenomenon]) in order to identify predictors of hemodynamic response and specifically to assess whether patients with Raynaud's phenomenon and pulmonary hypertension were more likely to respond to nifedipine."3.67Nifedipine in pulmonary arterial hypertension. Importance of Raynaud's phenomenon. ( Borer, JS; Fisher, J; Likier, HM; Mack, RJ; Schiff, AN, 1987)
"To detect whether pulmonary vascular responsiveness is a factor which can aggravate the pulmonary hypertension induced by irreversible pulmonary fibrosis, we examined the acute hemodynamic effects of low-flow oxygen and of nifedipine both at rest and during exercise in 8 patients with idiopathic pulmonary fibrosis (IPF)."3.67Pulmonary vascular responsiveness at rest and during exercise in idiopathic pulmonary fibrosis: effects of oxygen and nifedipine. ( Galavotti, V; Gunella, G; Papiris, S; Sturani, C, 1986)
"The favourable effect of long-term (36 months) treatment with nifedipine in a case of primary pulmonary hypertension is described."3.67Long-term favourable effect of nifedipine in primary pulmonary hypertension. Report of a case with hemodynamic evaluation after 3 and after 16 months and with clinical follow-up during 36 months. ( Di Donato, M; Musante, R, 1985)
"We evaluated the hemodynamic effects of the calcium antagonist nifedipine in 13 consecutive patients admitted to the intensive care unit with secondary pulmonary hypertension."3.67Hemodynamic effects of nifedipine on secondary pulmonary hypertension in man. ( Carlier, J; Cremers, S; D'Orio, V; el Allaf, D; Garzaniti, N; Marcelle, R, 1985)
"In 10 patients with advanced chronic lung disease and pulmonary hypertension central haemodynamics and pulmonary gas exchange were studied at rest and during exercise, before and during continuous infusion of the calcium antagonist felodipine, which lowers vascular resistance by selective action on vascular smooth muscle."3.67The effect of a new calcium antagonist, felodipine, on pulmonary hypertension and gas exchange in chronic obstructive lung disease. ( Bratel, T; Hedenstierna, G; Nyquist, O; Ripe, E, 1985)
"The effects of nifedipine on hemodynamics and blood gases were studied in 10 patients with pulmonary hypertension secondary to chronic obstructive lung disease."3.67Two-week nifedipine treatment for pulmonary hypertension complicating chronic obstructive lung disease. ( Arnaud, A; Guintoli, A; Philip-Joet, F; Saadjian, A; Torresani, J, 1985)
"A 64-year-old woman with systemic sclerosis and pulmonary hypertension underwent Swan-Ganz catheterization to test her response to the calcium channel blocker nifedipine."3.67Transient effect of nifedipine on pulmonary hypertension of systemic sclerosis. ( Fudman, EJ; Kelling, DG, 1985)
"To evaluate the potential value of nifedipine treatment for primary pulmonary hypertension, hemodynamic and scintigraphic measurements were made before and 15 to 30 minutes after nifedipine, 10 to 20 mg, was given sublingually to nine patients."3.66Treatment of primary pulmonary hypertension with nifedipine. A hemodynamic and scintigraphic evaluation. ( Firth, BG; Hillis, LD; Nicod, P; Rubin, LJ, 1983)
"The effects of 3 types of vasoactive agents, hydralazine, nifedipine and amrinone, were evaluated in 7 patients with primary pulmonary hypertension (PPH)."3.66Comparative actions of hydralazine, nifedipine and amrinone in primary pulmonary hypertension. ( Ganz, R; Levy, PS; Rich, S, 1983)
"The effect of sublingual nifedipine (20 mg) on haemodynamics at rest and during bicycle ergometry in supine position was assessed in 22 patients with precapillary pulmonary hypertension (obstructive form: n = 17, restrictive form: n = 2, combined obstructive-restrictive: n = 3)."3.66[Effect of nifedipine on hemodynamics in precapillary pulmonary hypertension at rest and during exertion]. ( Fridrich, L; Gassner, A; Lenz, K; Pichler, M; Sykora, J; Tizek, H, 1983)
"The effects of nifedipine on hemodynamics and pulmonary gas exchange were investigated in two patients with primary pulmonary hypertension."3.66Effects of nifedipine on ventilation/perfusion matching in primary pulmonary hypertension. ( Denolin, H; Mélot, C; Mols, P; Naeije, R; Vandenbossche, JL, 1983)
"Clinical experience with calcium antagonists in congestive heart failure has, to date, been mainly restricted to the use of nifedipine but there is either no or only a limited extent of information available on diltiazem and verapamil."3.66Calcium antagonists in heart failure. ( Camerini, F; Klugmann, S; Salvi, A, 1983)
"Progressive dyspnea and syncope occurred in a young woman with primary pulmonary hypertension despite therapy with hydralazine."3.66Hemodynamic effects of nifedipine in primary pulmonary hypertension. ( Douglas, JS, 1983)
"In a 22-year-old woman with primary pulmonary hypertension resistant to all previous attempts to reduce the pulmonary vascular resistance, there was dramatic improvement after the first dose of nifedipine, 20 mg po, which was not sustained with subsequent doses."3.66Rapid attenuation of response to nifedipine in primary pulmonary hypertension. ( Fennell, WH; Luck, JC; Tortoledo, F; Wood, BA, 1982)
"Thirty-three COPD patients (II = 12, ID = 11, DD = 10) with placebo or nifedipine (10 mg) underwent right heart catheterization with exercise, and systemic and pulmonary haemodynamic variables were examined."2.71Acute effects of nifedipine administration in pulmonary haemodynamics and oxygen delivery during exercise in patients with chronic obstructive pulmonary disease: implication of the angiotensin-converting enzyme gene polymorphisms. ( Kanazawa, H; Tateishi, Y; Yoshikawa, J, 2004)
"Almitrine infusion was followed by an increase in PaO2 (20%) and PVR (48%)."2.67Nifedipine inhibits the effects of almitrine in patients suffering from pulmonary artery hypertension secondary to chronic obstructive pulmonary disease. ( Arnaud, A; Barret, A; Levy, S; Philip-Joët, F; Saadjian, A, 1993)
"High altitude pulmonary edema (HAPE) is characterized by marked pulmonary hypertension."2.67Prevention and treatment of high altitude pulmonary edema by a calcium channel blocker. ( Bärtsch, P; Maggiorini, M; Noti, C; Oelz, O; Ritter, M; Vock, P; Waber, U, 1992)
"Primary pulmonary hypertension is a progressive, fatal disease of unknown cause."2.67The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension. ( Kaufmann, E; Levy, PS; Rich, S, 1992)
"The advantages of long-term administration of vasodilators in the treatment of chronic cor pulmonale were investigated after informed consent in 60 patients with obstructive respiratory insufficiency (56 men, 4 women, mean age 63."2.66One-year clinical study on nifedipine in the treatment of pulmonary hypertension in chronic obstructive lung disease. ( Arnaud, A; Philip-Joet, F; Saadjian, A; Surpas, P; Vestri, R, 1988)
"This long-term controlled study was undertaken to assess the haemodynamic effects of chronic administration of Nifedipine (N)."2.66Long-term treatment of chronic obstructive lung disease by Nifedipine: an 18-month haemodynamic study. ( Arnaud, AG; Philip-Joet, FF; Saadjian, AY; Vestri, R, 1988)
"Foridon is not indicated for the treatment of renal hypertension."2.66[Use of foridon in the treatment of arterial hypertension and hypertension of the lesser circulation]. ( Demidiuk, VT; Mikunis, RI; Monastyrskiĭ, IuI; Pshelutskiĭ, FF; Serkova, VK, 1988)
"Pretreatment with nifedipine significantly attenuated the hypoxia-induced increase in mean pulmonary artery pressure by 53% and of the mean pulmonary vascular resistance index by 50%."2.66Nifedipine attenuates acute hypoxic pulmonary vasoconstriction in patients with chronic obstructive pulmonary disease. ( Burghuber, OC, 1987)
"Primary pulmonary hypertension is a rare disease with a median survival of only 2."2.39[Therapy of primary pulmonary arterial hypertension: current status]. ( Solèr, M, 1994)
"Excessive pulmonary vascular remodeling is mediated by increased proliferation of pulmonary arterial smooth muscle cells (PASMC) due to PASMC dedifferentiation from a contractile or quiescent phenotype to a proliferative or synthetic phenotype."1.42Upregulated expression of STIM2, TRPC6, and Orai2 contributes to the transition of pulmonary arterial smooth muscle cells from a contractile to proliferative phenotype. ( Fernandez, RA; Gu, Y; Makino, A; Mehta, D; Smith, KA; Song, S; Tang, H; Tauseef, M; Wan, J; Yuan, JX, 2015)
"Oral nifedipine or placebo was administered to alternating patients."1.38Nifedipine for the treatment of high altitude pulmonary edema. ( Basnet, S; Deshwal, R; Iqbal, M, 2012)
"Myocyte apoptosis and muscle atrophy were significantly decreased with irbesartan compared with untreated CHF rats."1.31Beneficial effects on skeletal muscle of the angiotensin II type 1 receptor blocker irbesartan in experimental heart failure. ( Angelini, A; Battista Ambrosio, G; Dalla Libera, L; Ravara, B; Rossini, K; Sandri, M; Thiene, G; Vescovo, G, 2001)
"Pretreatment with indomethacin, isoproterenol, or nifedipine significantly reduced post-air-embolism lung water content to 85."1.30Pharmacologic modulation of pulmonary vascular permeability during air embolism. ( Huang, KL; Lin, YC, 1997)
" In these nonresponders, nine serious adverse events were observed with CCB (38%)."1.30Inhaled nitric oxide as a screening agent for safely identifying responders to oral calcium-channel blockers in primary pulmonary hypertension. ( Fartoukh, M; Herve, P; Humbert, M; Jagot, JL; Parent, F; Simonneau, G; Sitbon, O; Taravella, O, 1998)
"Primary pulmonary hypertension is a rare, incurable, and progressive disease."1.29Primary pulmonary hypertension in pregnancy: a case report. ( Asseryanis, E; Egarter, C; Kiss, H; Kneussl, M; Putz, D, 1995)
"Nifedipine was administered in 20 mg doses hourly during right cardiac catheterization and was repeated after 1 hour until a decrease in systemic pressure occurred."1.29[Effect of large doses of nifedipine on pulmonary hypertension in patients with recurrent pulmonary thromboembolism]. ( Fijałkowska, A; Filipecki, S; Hajduk, B; Pałasiewicz, G; Polowiec, Z; Radomyski, A; Tomkowski, W, 1994)
"Nifedipine (10 mg/kg) was administered intraperitoneally every day."1.29The effect of nifedipine on monocrotaline-induced pulmonary hypertension in rats. ( Harada, Y; Inoue, M; Mori, C; Tanaka, O; Watanabe, K, 1993)
"The nifedipine effect was age related."1.28Long-term hemodynamic effects of nifedipine on congenital heart disease with Eisenmenger's mechanism in children. ( Schlemmer, M; Wimmer, M, 1992)
"Nifedipine was discontinued after 8 months due to lack of improvement in the patient's state."1.28[Treatment of primary pulmonary hypertension with high doses of nifedipine controlled by Doppler echocardiography]. ( Filipecki, S; Pasierski, T; Radomyski, A; Tomkowski, W; Torbicki, A, 1991)
" Under this aspect we examined 44 patients by right heart catheterisation at rest and at exercise before and after sublingual application of a single dose of 20 mg nifedipine (Corinfar) as well as under continuous dosage of 30-60 mg daily."1.28The influence of nifedipine (Corinfar) on pulmonary hypertension in chronic obstructive lung disease. ( Evers, H; Harzbecker, K; Orschekowski, H; Schauer, J; Schilling, W; Steiniger, L; Winkler, J, 1990)
"Pulmonary hypertension was produced by continuous intravenous administration of U46619 to halothane-anesthetized sheep."1.28Hemodynamic effects of diltiazem during vasoconstrictor pulmonary hypertension in sheep. ( Finn, JC; Pearl, RG, 1990)
"Nifedipine was found to be the most effective."1.28[A case of primary pulmonary hypertension with high venous thromboxane B2 concentration]. ( Abe, S; Kawakami, Y; Kishi, F; Miyamoto, K; Nagata, H; Nakano, T; Suzuki, A; Takahashi, S; Takai, S, 1990)
"Primary pulmonary hypertension is an uncommon but serious disease that often results in debilitating symptoms and early death."1.28[Evaluation of the effects of vasodilator therapy in primary pulmonary hypertension. Experience in 7 cases]. ( Aimè, E; Angoli, L; Arbustini, E; Bargiggia, G; Campana, C; Gavazzi, A; Graziano, G; Lanzarini, L; Montemartini, C; Mussini, A, 1990)
" During 12 weeks of prednisone treatment in a dosage of 40 mg daily, her condition markedly deteriorated clinically and hemodynamically as manifested by pulmonary artery pressure (PAP), pulmonary vascular resistance (PVR), cardiac output (CO), mixed venous O2 saturation, and systemic vascular resistance (SVR)."1.28Nifedipine and prazosin in the management of pulmonary hypertension in CREST syndrome. ( Dresner-Feigin, R; Galun, E; Glikson, M; Pollack, A; Rubinow, A, 1990)
"Primary pulmonary hypertension is a disease of unknown etiology."1.28[Nifedipine in primary pulmonary hypertension while waiting for heart-lung transplantation]. ( Petersen, TI; Svanegård, J; Thayssen, P, 1989)
"Nifedipine was then administered sublingually in a dose of 1 mg/kg and produced an immediate and dramatic improvement in the right radial artery pO2 that was sustained despite persistence of the right-to-left shunt."1.28[Efficacy of nifedipine on refractory hypoxemia associated with diaphragmatic hernia in the newborn infant. Apropos of a case]. ( Burguet, A; Destuynder, R; Fromentin, C; Menget, A, 1989)
"Nifedipine is a potent slow channel calcium antagonist and systemic vasodilator recently reported to attenuate hypoxic pulmonary vasoconstriction in man."1.26Inhibition of hypoxic pulmonary vasoconstriction by nifedipine. ( Kennedy, T; Summer, W, 1982)
"Nifedipine is a calcium antagonistic drug which reduces elevated vascular resistances."1.26Hemodynamic effects of nifedipine in pulmonary hypertension. ( Camerini, F; Fioretti, P; Klugmann, S; Salvi, A, 1982)

Research

Studies (265)

TimeframeStudies, this research(%)All Research%
pre-1990144 (54.34)18.7374
1990's79 (29.81)18.2507
2000's24 (9.06)29.6817
2010's17 (6.42)24.3611
2020's1 (0.38)2.80

Authors

AuthorsStudies
Luks, AM2
Swenson, ER2
Parise, I1
Li, Y1
Zhang, Y2
Saigal, A1
Ng, WK1
Tan, RB1
Chan, SY1
Fernandez, RA1
Wan, J2
Song, S2
Smith, KA2
Gu, Y1
Tauseef, M1
Tang, H1
Makino, A2
Mehta, D1
Yuan, JX3
Wang, RX1
He, RL1
Jiao, HX1
Dai, M1
Mu, YP1
Hu, Y1
Wu, ZJ1
Sham, JS1
Lin, MJ1
Fan, Z1
Chen, Y1
Liu, H1
Yanamandra, U1
Nair, V1
Singh, S1
Gupta, A1
Mulajkar, D1
Yanamandra, S1
Norgais, K1
Mukherjee, R1
Singh, V1
Bhattachar, SA1
Patyal, S1
Grewal, R1
Chopra, B1
Haworth, SG2
Hislop, AA1
Cui, B1
Cheng, YS1
Dai, DZ2
Li, N1
Zhang, TT1
Dai, Y2
Plumley, C1
Gorman, EM1
El-Gendy, N1
Bybee, CR1
Munson, EJ1
Berkland, C1
Rodat-Despoix, L1
Aires, V1
Ducret, T1
Marthan, R1
Savineau, JP1
Rousseau, E1
Guibert, C1
Bozbaş, SS1
Bozbaş, H1
Atar, A1
Ulubay, G1
Oner Eyüboğlu, F1
Yilmaz, R1
Kayikçioğlu, M1
Kültürsay, H1
Yang, Y1
Gao, M1
Guo, Y1
Qiao, J1
Bailey, DM1
Dehnert, C1
Menold, E1
Castell, C1
Schendler, G1
Faoro, V1
Gutowski, M1
Evans, KA1
Taudorf, S1
James, PE1
McEneny, J1
Young, IS1
Mairbäurl, H1
Bärtsch, P4
Berger, MM1
Mou, XB1
Li, SZ1
Gao, YQ1
Liou, FY1
Ye, GL1
Tang, HY1
Zhou, XB1
Cheng, GL1
Hall, SM1
Davie, N1
Klein, N1
Deshwal, R1
Iqbal, M1
Basnet, S1
S K S, S1
P, H1
Mathew, T1
S, S1
M, C1
Forrest, AS1
Joyce, TC1
Huebner, ML1
Ayon, RJ1
Wiwchar, M1
Joyce, J1
Freitas, N1
Davis, AJ1
Ye, L1
Duan, DD1
Singer, CA1
Valencik, ML1
Greenwood, IA1
Leblanc, N1
Jones, BE1
Stokes, S1
McKenzie, S1
Nilles, E1
Stoddard, GJ1
Yamamura, A1
Yamamura, H1
Guo, Q1
Zimnicka, AM1
Ko, EA1
Pohl, NM1
Zeifman, A1
Nagaoka, T1
Morio, Y1
Casanova, N1
Bauer, N1
Gebb, S1
McMurtry, I1
Oka, M2
Andreassen, AK1
Geiran, O1
Madsen, S1
Hognestad, A1
Simonsen, S1
Kanazawa, H1
Tateishi, Y1
Yoshikawa, J1
Oriowo, MA1
Schlag, K1
Opitz, C1
Wensel, R1
Felix, S1
Ewert, R1
Maggiorini, M3
Yuan, SH1
Guan, L1
Ji, M1
Rosati, E1
Butera, G1
Bossone, E4
De Felice, C1
Latini, G1
Uner, A1
Dogan, M1
Demirtas, M1
Açikgöz, M1
Temel, H1
Kaya, A1
Caksen, H1
Khan, SA1
Gelb, BD1
Nguyen, KH1
Stone, KS1
Scordo, KA1
Krikler, DM1
Rowland, E1
Ellrodt, AG1
Singh, BN1
Rees, J1
Wise, JR1
Feret, J1
Bruet, A1
Simon, N1
Duruy, D1
Nouailhat, F1
Havel, V1
Král, B2
Eliás, J1
Hamet, A2
Cernohorský, D2
Rubin, LJ4
Coma-Canella, I1
Lopez-Sendon, J1
Drummond, WH1
Gaucher, LR1
Payen, DM1
Minsart, PJ1
Peltier, PM1
Ordronneau, JJ1
Grolleau, JY1
Lunde, P1
Rasmussen, K1
Fisher, J2
Borer, JS2
Moses, JW1
Goldberg, HL1
Niarchos, AP1
Whitman, HH1
Mermelstein, M1
Packer, M2
Medina, N1
Yushak, M1
van der Wall, EE1
Tuinzing, DB1
Hes, J1
Dickstein, PJ1
Trindade, O1
Goldberg, RN1
Bancalari, E1
Young, TE1
Lundquist, LJ1
Chesler, E2
Weir, EK3
Nicod, P1
Hillis, LD2
Firth, BG1
Rich, S11
Ganz, R1
Levy, PS4
Gassner, A3
Pichler, M1
Fridrich, L3
Sykora, J1
Tizek, H1
Lenz, K1
Krol, RC1
Evans, AT1
Albright, DP1
Reilly, JM1
Brown, J1
Roman, M1
Vacek, JL1
Kennedy, TP2
Michael, JR2
Huang, CK1
Kallman, CH1
Zahka, K1
Schlott, W1
Summer, W2
Tobey, MA1
Arnman, K1
Rydén, L1
Smedgård, P1
Thorhallsson, E1
Olivari, MT1
Levine, TB1
Cohn, JN1
Stanbrook, HS1
Morris, KG2
McMurtry, IF2
Pannarale, G1
Gaspardone, A1
Acconcia, MC1
Valente, A1
Mélot, C1
Naeije, R1
Mols, P1
Vandenbossche, JL1
Denolin, H1
De Feyter, PJ1
Kerkkamp, HJ1
de Jong, JP1
Farber, HW1
Karlinsky, JB1
Faling, LJ1
Klugmann, S3
Salvi, A3
Camerini, F3
Douglas, JS1
Saito, D1
Haraoka, S1
Yoshida, H2
Kusachi, S1
Yasuhara, K1
Nishihara, M1
Fukuhara, J1
Hagashima, H1
Ocken, S1
Reinitz, E1
Strom, J1
Berkenboom, G1
Sobolski, J1
Stoupel, E1
Durandy, Y1
Pansard, Y1
Mankikian, B1
Dequirot, A1
Kennedy, T1
Wood, BA1
Tortoledo, F1
Luck, JC1
Fennell, WH2
Jezek, V1
Michaljanic, A1
Fucík, J1
Jezková, L1
Krása, H1
Gaul, G1
Blazek, G1
Deutsch, E1
Heeger, H1
Levigard, RM1
Assad, JE1
Fioretti, P1
Dalal, JJ1
Griffiths, BE1
Henderson, AH1
Alberti, E1
Thomas, D1
Drobinski, G1
Komajda, M1
Grosgogeat, Y1
Crowley, MR1
Fineman, JR1
Soifer, SJ1
Prasad, N1
Lang, CC1
McAlpine, HM1
Choy, AM1
MacDonald, TM1
Struthers, AD1
Saadjian, A8
Philip-Joët, F6
Barret, A1
Levy, S1
Arnaud, A8
Li, MR1
Chen, SC1
Ma, G1
Ghali, JK1
Goerre, S1
Wenk, M1
Lüscher, TF1
Niroomand, F1
Hohenhaus, E1
Oelz, O3
Reinhart, WH1
Jolliet, P2
Thorens, JB2
Chevrolet, JC2
Kiss, H1
Egarter, C1
Asseryanis, E1
Putz, D1
Kneussl, M1
Volkova, LI2
Shteĭngart, IuN1
Weiser, MC1
Majack, RA1
Tucker, A1
Orton, EC1
Solèr, M1
Husebye, ES1
Wibell, L1
Pałasiewicz, G1
Tomkowski, W2
Hajduk, B1
Fijałkowska, A1
Radomyski, A2
Filipecki, S2
Polowiec, Z1
Machet, L1
Callens, A1
Machet, MC1
Desveaux, B1
Vaillant, L1
Ben Jrad, I1
Slimane, ML1
Boujnah, MR1
Ben Hamda, K1
Ameur, Y1
Partanen, J1
Nieminen, MS1
Luomanmäki, K1
Bujak, K1
Kozik, T1
Inoue, M1
Harada, Y1
Watanabe, K1
Mori, C1
Tanaka, O1
Inbar, S2
Schrader, BJ3
Kaufmann, E4
Vestal, RE2
Ogata, M1
Ohe, M1
Shirato, K1
Takishima, T1
Nootens, M2
Kalra, L1
Bone, MF1
el Hawy, AM1
Negm, IA1
el-Rakaybe, A1
Abdel-Maged, AI1
Mansour, RE1
Phillips, BG1
Bauman, JL1
Schoen, MD1
Hoon, TJ1
Chaouat, A1
Kessler, R1
Weitzenblum, E1
Patole, SK1
Finer, NN1
Shimabukuro, M1
Chibana, T1
Nagamine, F1
Takasu, N1
Malik, AS1
Warshafsky, S1
Lehrman, S2
Bulpa, P1
Ritz, M1
Huang, KL1
Lin, YC1
Bragulat, E1
García, F1
Fernández, F1
Ballester, E1
Villalta, J1
Grau, JM1
Gallagher, MM1
Hart, CM1
Vaughan, CJ1
Sitbon, O1
Humbert, M1
Jagot, JL1
Taravella, O1
Fartoukh, M1
Parent, F1
Herve, P1
Simonneau, G1
Atz, AM1
Wessel, DL1
Ricciardi, MJ2
Knight, BP1
Martinez, FJ2
Rubenfire, M4
Antezana, AM1
Antezana, G1
Aparicio, O1
Noriega, I1
Velarde, FL1
Richalet, JP1
Easterling, TR1
Ralph, DD1
Schmucker, BC1
Bîrsan, T1
Kranz, A1
Mares, P1
Artemiou, O1
Taghavi, S1
Zuckermann, A1
Klepetko, W1
Olschewski, H1
Ghofrani, HA1
Walmrath, D1
Schermuly, R1
Temmesfeld-Wollbruck, B1
Grimminger, F1
Seeger, W1
Fike, CD1
Kaplowitz, MR1
Horstman, DJ1
McCall, DA1
Frank, DU1
Rich, GF1
Barst, RJ2
Bach, DS1
Armstrong, WF1
Collados, MT1
Sandoval, J1
López, S1
Massó, FA1
Páez, A1
Borbolla, JR1
Montaño, LF1
Paciocco, G2
Erba, H1
Cockrill, BA1
Kacmarek, RM1
Fifer, MA1
Bigatello, LM1
Ginns, LC1
Zapol, WM1
Semigran, MJ1
Golovina, VA1
Platoshyn, O1
Bailey, CL1
Wang, J1
Limsuwan, A1
Sweeney, M1
Bayraktar, Y1
Tanaci, N1
Egesel, T1
Gököz, A1
Balkanci, F1
Dalla Libera, L1
Ravara, B1
Angelini, A1
Rossini, K1
Sandri, M1
Thiene, G1
Battista Ambrosio, G1
Vescovo, G1
Tamura, M1
Kurumatani, H1
Matsushita, T1
Pielsticker, E1
Gillespie, B1
McMahon, CJ1
Kadkin, J1
Nihill, MR1
Xu, JY1
Li, BX1
Cheng, SY1
Wimmer, M4
Schlemmer, M4
Cheng, X1
Ritter, M2
Noti, C2
Waber, U2
Vock, P2
Domenighetti, GM1
Saglini, VG1
Kaufmann, L1
Vorob'ev, LP3
Maev, IV3
Davis, DA1
Russo, P1
Alpert, MA2
Pressly, TA2
Mukerji, V2
Lambert, CR1
Mukerji, B1
Panayiotou, H1
Sharp, GC2
Poloński, L2
Polońska, A2
Tendera, M2
Wodniecki, J2
Krzywiecki, A2
Pasierski, T1
Torbicki, A1
Prigogine, T1
Waterlot, Y1
Gottignies, P1
Verhoeven, A1
Decroly, P1
Kaziulin, AN1
Andreev, NG1
Yuan, H1
Uren, NG1
Oakley, CM2
Johnson, CE1
Beekman, RH2
Kostyshak, DA1
Nguyen, T1
Oh, DM1
Amidon, GL1
Ribeiro, PA1
Sivanandan, V1
Shaikh, A1
Chalak, W1
Zaman, L1
Duran, CM1
Liu, Z1
Yu, RJ1
Dubiel, JP1
Nikodemowicz, M1
Zmudka, K1
Mazurek, S1
Królikowski, T1
Prielipp, RC2
McLean, R1
Rosenthal, MH2
Pearl, RG3
Salzer, U1
Marx, M1
Proll, E1
Schauer, J2
Orschekowski, H2
Steiniger, L1
Winkler, J1
Schilling, W1
Harzbecker, K1
Evers, H1
Sommer, G2
Magometschnigg, D2
Priol, A1
Finn, JC1
Nakano, T1
Takai, S1
Suzuki, A1
Miyamoto, K1
Nagata, H1
Kishi, F1
Abe, S1
Kawakami, Y1
Takahashi, S1
Lanzarini, L1
Gavazzi, A1
Mussini, A1
Graziano, G1
Campana, C1
Bargiggia, G1
Angoli, L1
Aimè, E1
Arbustini, E1
Montemartini, C1
Luther, R1
Wichert, H1
Köhler, E1
Banditt, P1
Walther, H1
Glikson, M1
Pollack, A1
Dresner-Feigin, R1
Galun, E1
Rubinow, A1
Zhou, X1
Morrison, DA1
Gay, RG1
Feldshon, D1
Sampliner, RE1
Petersen, TI1
Svanegård, J1
Thayssen, P1
Palombo, C1
Mian, M1
Bertelli, A1
Mazza, F1
Morra, AM1
Morra, MG1
Catalano, M1
Contiello, V1
Polcino, A1
Oida, A1
Ogawa, K1
Nagao, I1
Tsukada, K1
Yoshimura, M1
Sawada, M3
Chen, H1
Wang, SZ1
Bai, YR1
Himmel, W1
Paleev, NR1
Tsa'rkova, LN1
Uribe-Echevarria, EE1
Baklykova, SN1
Novoderezhkina, LB1
Turetta, F1
De Stefani, R1
Milanesi, A1
Cannizzaro, A1
Stievano, N1
Bossi, A1
Simone, M1
Davidson, A1
Bossuyt, A1
Dab, I1
Dantzker, DR3
D'Alonzo, GE3
Gianotti, L2
Fuentes, F1
Nickeson, D1
Emerson, M1
Meurice, JC1
Boutaud, P1
Herpin, D1
Ingrand, P1
Boita, F1
Underner, M1
Patte, F1
Vestri, R5
Pohar, B1
Grad, A1
Mozina, M1
Rakovec, P1
Horvat, M1
Burguet, A1
Menget, A1
Fromentin, C1
Destuynder, R1
Agostoni, P2
Doria, E2
Galli, C2
Tamborini, G2
Guazzi, MD1
Buescher, P1
Farrukh, I1
Lodato, R1
Rock, PC1
Gottlieb, J1
Gurtner, G1
de la Monte, SM1
Hutchins, GM1
Shao, MG1
Cai, YN1
Deng, XX1
Philip-Joft, F1
Lagier, F1
Joet, FP1
Miyamori, R1
Marutani, K1
Norisue, H1
Fukui, T1
Handa, S2
Hosoda, Y1
Schranz, D1
Huth, RG1
Stopfkuchen, H1
Jüngst, BK1
Surpas, P1
Saadjian, AY1
Philip-Joet, FF1
Arnaud, AG1
Mikunis, RI1
Monastyrskiĭ, IuI1
Pshelutskiĭ, FF1
Serkova, VK1
Demidiuk, VT1
Tran N'guyen, A1
Torresani, J2
Klicpera, M1
Ebner, F2
Sil'vestrov, VP1
Surovov, IuA1
Semin, SN1
Pakulin, IA1
Larin, NV1
Köhler, W1
von Jan, V1
Schmidt, H1
Corriveau, ML1
Rosen, BJ1
Keller, CA1
Chun, DS1
Dolan, GF1
Hussein, A1
Koch, I1
Schmidt-Redemann, B1
Brownlee, JR1
Rosenthal, A1
Mohsenifar, Z1
Jasper, AC2
Koerner, SK2
Araki, Y2
Tanaka, N1
Kudoh, S1
Sakaguchi, K2
Fujita, K1
Fiorentini, C1
Guazzi, M1
Wilczek, K1
Coli, A1
Ammirati, A1
Dina, MA1
Khosseĭn, A2
Mukharliamov, NM1
Mareev, VIu2
Lobova, NM2
Ageev, FT2
Rozkovec, A1
Stradling, JR1
Shepherd, G1
MacDermot, J1
Dollery, CT1
Winkler, A1
Jackson, RW1
Benge, JM1
Vereshchagina, GN1
Vasilenko, GP1
Kuleshova, TV1
Kasian, GF1
Ninan, A1
Duncan, WJ1
Bingham, WT1
Mersal, A1
Tyrrell, MJ1
Sankaran, K1
Sazonova, LN1
Berisha, S1
Goda, A1
Kastrati, A1
Frasheri, A1
Popa, Y1
Paczek, A1
Rydlewska-Sadowska, W1
Johnson, DC1
Joshi, RC1
Mehta, R1
Cunnington, AR1
Hart, K1
Kieras, K1
Brundage, BH2
Barreto, SM1
de Freitas, FM2
Grisanti, M1
Vicencio, M1
Barreto, BM1
Mangieri, E1
Puddu, E1
Martuscelli, E1
Lanti, M1
Danesi, A1
Nigri, A1
Reale, A1
Marmor, AT1
Michaeli, S1
Plich, M1
Frankel, A1
Schneeweiss, A1
Mack, RJ1
Likier, HM1
Schiff, AN1
Halpern, SM1
Shah, PK1
Goldberg, HS1
Obata, Y1
Burghuber, OC1
Yamaguchi, S1
Tsuiki, K1
Hayasaka, M1
Oguma, M1
Ohta, I1
Kaminishi, T1
Sukekawa, H1
Kanaya, T1
Yasui, S1
Bratel, T2
Hedenstierna, G2
Nyquist, O2
Ripe, E2
Fujii, I1
Ohonishi, S1
Yamazaki, H1
Nakamura, Y1
Sturani, C1
Papiris, S1
Galavotti, V1
Gunella, G1
Kochanek, PM1
Zaritsky, A1
Lehrman, SG1
Hollander, RC1
Hecht, SR1
Berger, M1
Berdoff, RL1
Van Tosh, A1
Stimola, JM1
Woroszylska, M1
Piotrowska, J1
Ruzyłło, W1
Lubiszewska, B1
Freggiaro, V1
Davi, R1
Morelloni, S1
Pareti, G1
Allegri, M1
Okada, O1
Naito, T1
Kohchi, F1
Yamagishi, F1
Kuriyama, T1
Sugita, T1
Watanabe, S1
Hasebe, N1
Onodera, S1
Ohmiya, H1
Tanaka, M1
Sakamoto, K1
Honda, Y1
Ikeda, Y1
Sakai, E1
Kuwajima, T1
Musante, R1
Di Donato, M1
Archer, SL1
Yankovich, RD1
Garzaniti, N1
el Allaf, D1
D'Orio, V1
Cremers, S1
Marcelle, R1
Carlier, J1
Winniford, MD1
Aromatorio, GJ1
Uretsky, BF1
Reddy, PS1
Santos Bouza, AA1
López Pérez, JM1
Philips, JB1
Lyrene, RK1
Leslie, GI1
McDevitt, M1
Cassady, G1
Batra, AK1
Segall, PH1
Ahmed, T1
Gladman, DD1
Sternberg, L1
Ohar, J1
Polatty, C1
Robichaud, A1
Fowler, A1
Vetrovec, G1
Glauser, F1
Muramoto, A1
Caldwell, J1
Albert, RK1
Lakshminarayan, S1
Butler, J1
Domenighetti, G1
Guintoli, A1
Galiè, N1
Sanguinetti, M1
Marrozzini, C1
Magnani, B1
Fudman, EJ1
Kelling, DG1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Calcium Channel Blockers in Nitric Oxide Non-responder Pulmonary Arterial Hypertension.[NCT01645826]0 participants (Actual)Interventional2012-07-31Withdrawn (stopped due to no participants agreed to enroll since study start)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

24 reviews available for nifedipine and Hypertension, Pulmonary

ArticleYear
COVID-19 Lung Injury and High-Altitude Pulmonary Edema. A False Equation with Dangerous Implications.
    Annals of the American Thoracic Society, 2020, Volume: 17, Issue:8

    Topics: Acetazolamide; Altitude Sickness; Betacoronavirus; Carbonic Anhydrase Inhibitors; Coronavirus Infect

2020
Travelling safely to places at high altitude - Understanding and preventing altitude illness.
    Australian family physician, 2017, Volume: 46, Issue:6

    Topics: Acclimatization; Acetazolamide; Altitude; Altitude Sickness; Anticonvulsants; Antiemetics; Calcium C

2017
Research advances in pathogenesis and prophylactic measures of acute high altitude illness.
    Respiratory medicine, 2018, Volume: 145

    Topics: Acetazolamide; Acute Disease; Altitude Sickness; Calcium Channel Blockers; Carbonic Anhydrase Inhibi

2018
Calcium channel blockers for pulmonary arterial hypertension.
    The Cochrane database of systematic reviews, 2015, Sep-25, Issue:9

    Topics: Aged; Benzimidazoles; Benzoates; Calcium Channel Blockers; Humans; Hypertension, Pulmonary; Middle A

2015
[Current approach to the treatment of pulmonary arterial hypertension and our experience in the Cardiology Department of Medicine Faculty of Ege University].
    Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2009, Volume: 37, Issue:8

    Topics: Antihypertensive Agents; Diltiazem; Disease Progression; Epoprostenol; Humans; Hypertension, Pulmona

2009
High altitude-induced pulmonary oedema.
    Cardiovascular research, 2006, Oct-01, Volume: 72, Issue:1

    Topics: Acclimatization; Altitude Sickness; Disease Susceptibility; Humans; Hypertension, Pulmonary; Nifedip

2006
Understanding the calcium channel blockers.
    Heart & lung : the journal of critical care, 1984, Volume: 13, Issue:5

    Topics: Action Potentials; Angina Pectoris; Animals; Arrhythmias, Cardiac; Arteriosclerosis; Calcium; Calciu

1984
Clinical value of calcium antagonists in treatment of cardiovascular disorders.
    Journal of the American College of Cardiology, 1983, Volume: 1, Issue:1

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Angina Pectoris, Variant; Arrhythmias, Cardiac; Calciu

1983
Clinical applications of slow channel blocking compounds.
    Pharmacology & therapeutics, 1983, Volume: 23, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Blood Platelets; Blood Vessels; Calcium

1983
Cardiovascular effects of vasodilator therapy for pulmonary arterial hypertension.
    Clinics in chest medicine, 1983, Volume: 4, Issue:2

    Topics: Cardiac Output; Echocardiography; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmonary; Hypote

1983
Persistent pulmonary hypertension of the neonate (persistent fetal circulation syndrome).
    Advances in pediatrics, 1983, Volume: 30

    Topics: Acetylcholine; Calcium; Catecholamines; Epoprostenol; Homeostasis; Humans; Hypertension, Pulmonary;

1983
[Early pulmonary hypertension: current therapeutic prospectives].
    Cardiologia (Rome, Italy), 1982, Volume: 27, Issue:9

    Topics: Calcium Channel Blockers; Captopril; Diazoxide; Diltiazem; Humans; Hydralazine; Hypertension, Pulmon

1982
[Therapy of primary pulmonary arterial hypertension: current status].
    Schweizerische medizinische Wochenschrift, 1994, Oct-01, Volume: 124, Issue:39

    Topics: Humans; Hypertension, Pulmonary; Lung Transplantation; Nifedipine; Prognosis; Pulmonary Artery; Pulm

1994
Experimental and clinical effects of magnesium infusion in the treatment of neonatal pulmonary hypertension.
    Magnesium research, 1995, Volume: 8, Issue:4

    Topics: Animals; Blood Coagulation; Calcium Channel Blockers; Cyclic AMP; Cyclic GMP; Disease Models, Animal

1995
Sustained improvement of pulmonary haemodynamics with low-dose of nifedipine in primary pulmonary hypertension.
    European heart journal, 1996, Volume: 17, Issue:12

    Topics: Adult; Calcium Channel Blockers; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electr

1996
Meta-analysis of the long-term effect of nifedipine for pulmonary hypertension.
    Archives of internal medicine, 1997, Mar-24, Volume: 157, Issue:6

    Topics: Antihypertensive Agents; Clinical Trials as Topic; Humans; Hypertension, Pulmonary; Nifedipine; Time

1997
Do no harm.
    Chest, 1999, Volume: 116, Issue:5

    Topics: Calcium Channel Blockers; Contraindications; Echocardiography; Heart Septum; Heart Ventricles; Human

1999
Reversible pulmonary hypertension in POEMS syndrome--another etiology of triggered pulmonary vasculopathy?
    The Canadian journal of cardiology, 2000, Volume: 16, Issue:8

    Topics: Adrenal Cortex Hormones; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension, Pulmona

2000
[Pathophysiology, prevention and therapy of altitude pulmonary edema].
    Schweizerische medizinische Wochenschrift, 1992, Aug-04, Volume: 122, Issue:31-32

    Topics: Aldosterone; Altitude Sickness; Cell Membrane Permeability; Epinephrine; Humans; Hypertension, Pulmo

1992
[Calcium antagonists: accounts on new perspectives of their use and an update on side effects].
    La Clinica terapeutica, 1989, Feb-15, Volume: 128, Issue:3

    Topics: Adult; Animals; Asthma; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; Esophageal Ach

1989
[Effects of nifedipine in patients with chronic obstructive bronchitis and pulmonary hypertension undergoing artificial respiration].
    Annales francaises d'anesthesie et de reanimation, 1989, Volume: 8, Issue:3

    Topics: Hemodynamics; Humans; Hypertension, Pulmonary; Lung Diseases, Obstructive; Nifedipine; Oxygen; Respi

1989
[Nifedipine in the treatment of pulmonary hypertension. I--Primary pulmonary hypertension].
    Arquivos brasileiros de cardiologia, 1986, Volume: 46, Issue:5

    Topics: Adult; Blood Pressure; Female; Humans; Hypertension, Pulmonary; Male; Nifedipine; Vascular Resistanc

1986
Calcium antagonists in patients with cardiovascular disease. Current perspectives.
    Medicine, 1985, Volume: 64, Issue:1

    Topics: Angina Pectoris; Angina Pectoris, Variant; Atrial Fibrillation; Atrial Flutter; Benzazepines; Cardio

1985
Therapeutic application of calcium-channel antagonists for pulmonary hypertension.
    The American journal of cardiology, 1985, Jan-25, Volume: 55, Issue:3

    Topics: Animals; Calcium Channel Blockers; Cattle; Diltiazem; Hemodynamics; Humans; Hypertension, Pulmonary;

1985

Trials

26 trials available for nifedipine and Hypertension, Pulmonary

ArticleYear
Managing High-Altitude Pulmonary Edema with Oxygen Alone: Results of a Randomized Controlled Trial.
    High altitude medicine & biology, 2016, Volume: 17, Issue:4

    Topics: Adult; Altitude; Altitude Sickness; Anti-Inflammatory Agents; Combined Modality Therapy; Dexamethaso

2016
Comparative effects of losartan and nifedipine therapy on exercise capacity, Doppler echocardiographic parameters and endothelin levels in patients with secondary pulmonary hypertension.
    Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2010, Volume: 10, Issue:1

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Diastol

2010
Calcium antagonists, diltiazem and nifedipine, protect broilers against low temperature-induced pulmonary hypertension and pulmonary vascular remodeling.
    Animal science journal = Nihon chikusan Gakkaiho, 2010, Aug-01, Volume: 81, Issue:4

    Topics: Animals; Calcium Channel Blockers; Chickens; Cold Temperature; Diltiazem; Hypertension, Pulmonary; M

2010
Acute effects of nifedipine administration in pulmonary haemodynamics and oxygen delivery during exercise in patients with chronic obstructive pulmonary disease: implication of the angiotensin-converting enzyme gene polymorphisms.
    Clinical physiology and functional imaging, 2004, Volume: 24, Issue:4

    Topics: Aged; Biological Transport; Calcium Channel Blockers; Cross-Over Studies; Double-Blind Method; Exerc

2004
Nifedipine inhibits the effects of almitrine in patients suffering from pulmonary artery hypertension secondary to chronic obstructive pulmonary disease.
    Journal of cardiovascular pharmacology, 1993, Volume: 21, Issue:5

    Topics: Almitrine; Blood Gas Analysis; Cardiac Catheterization; Double-Blind Method; Female; Hemodynamics; H

1993
Endothelin-1 in pulmonary hypertension associated with high-altitude exposure.
    Circulation, 1995, Jan-15, Volume: 91, Issue:2

    Topics: Adult; Altitude; Altitude Sickness; Arteries; Blood Gas Analysis; Double-Blind Method; Endothelins;

1995
Effect of nifedipine on physiologic shunting and oxygenation in chronic obstructive pulmonary disease.
    The American journal of medicine, 1993, Volume: 94, Issue:4

    Topics: Administration, Sublingual; Blood Gas Analysis; Blood Pressure; Catheterization, Swan-Ganz; Female;

1993
Short-term effectiveness of nifedipine in secondary pulmonary hypertension.
    The American journal of cardiology, 1993, Jun-15, Volume: 71, Issue:16

    Topics: Adult; Female; Humans; Hypertension, Pulmonary; Male; Middle Aged; Nifedipine; Treatment Outcome

1993
Inhaled prostacyclin and iloprost in severe pulmonary hypertension secondary to lung fibrosis.
    American journal of respiratory and critical care medicine, 1999, Volume: 160, Issue:2

    Topics: Administration, Inhalation; Adult; Aged; Atrial Function, Right; Calcium Channel Blockers; Drug Ther

1999
Echocardiographic predictors of an adverse response to a nifedipine trial in primary pulmonary hypertension: diminished left ventricular size and leftward ventricular septal bowing.
    Chest, 1999, Volume: 116, Issue:5

    Topics: Administration, Oral; Adult; Blood Pressure; Calcium Channel Blockers; Echocardiography; Female; Hea

1999
Characterization of von Willebrand factor in primary pulmonary hypertension.
    Heart and vessels, 1999, Volume: 14, Issue:5

    Topics: Adrenergic beta-Agonists; Adult; Antigens; Biomarkers; Blotting, Western; Calcium Channel Blockers;

1999
Prevention and treatment of high altitude pulmonary edema by a calcium channel blocker.
    International journal of sports medicine, 1992, Volume: 13 Suppl 1

    Topics: Acute Disease; Administration, Sublingual; Adult; Altitude Sickness; Double-Blind Method; Humans; Hy

1992
The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension.
    The New England journal of medicine, 1992, Jul-09, Volume: 327, Issue:2

    Topics: Adult; Blood Pressure; Calcium Channel Blockers; Diltiazem; Humans; Hypertension, Pulmonary; Nifedip

1992
[Effects of corinfar, nitrosorbide and apressin on external respiration and blood flow in chronic obstructive bronchitis].
    Rossiiskii meditsinskii zhurnal : organ Ministerstva zdravookhraneniia RSFSR, 1992, Issue:1

    Topics: Blood Circulation; Bronchitis; Humans; Hydralazine; Hypertension, Pulmonary; Isosorbide Dinitrate; N

1992
[Drug therapy of pulmonary and portal hypertension in liver cirrhosis].
    Klinicheskaia meditsina, 1991, Volume: 69, Issue:2

    Topics: Adult; Aged; Antihypertensive Agents; Humans; Hypertension, Portal; Hypertension, Pulmonary; Isosorb

1991
[Modification of pulmonary hypertension in patients with chronic obstructive lung diseases using calcium antagonists in an acute trial].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1989, Jan-15, Volume: 44, Issue:2

    Topics: Administration, Sublingual; Adult; Aged; Clinical Trials as Topic; Humans; Hypertension, Pulmonary;

1989
[Nifedipine treatment of pulmonary hypertension as a complication of chronic obstructive diseases of the lungs].
    Klinicheskaia meditsina, 1989, Volume: 67, Issue:6

    Topics: Adult; Anti-Arrhythmia Agents; Clinical Trials as Topic; Female; Hemodynamics; Humans; Hypertension,

1989
[Long-term treatment of pulmonary hypertension in chronic obstructive bronchopneumopathies with nifedipine. Hemodynamic study over 18 months].
    Annales de cardiologie et d'angeiologie, 1989, Volume: 38, Issue:4

    Topics: Female; Follow-Up Studies; Hemodynamics; Humans; Hypertension, Pulmonary; Lung Diseases, Obstructive

1989
[Long-term clinical study of nifedipine in the treatment of pulmonary arterial hypertension in chronic obstructive bronchopneumopathies].
    Presse medicale (Paris, France : 1983), 1987, Sep-12, Volume: 16, Issue:29

    Topics: Clinical Trials as Topic; Female; Humans; Hypertension, Pulmonary; Lung Diseases, Obstructive; Male;

1987
[Hemodynamic effects of the administration of nifedipine over an 18-month period in pulmonary arterial hypertension in chronic obstructive bronchopneumopathies].
    Presse medicale (Paris, France : 1983), 1988, Feb-13, Volume: 17, Issue:5

    Topics: Hemodynamics; Humans; Hypertension, Pulmonary; Lung Diseases, Obstructive; Nifedipine

1988
One-year clinical study on nifedipine in the treatment of pulmonary hypertension in chronic obstructive lung disease.
    Respiration; international review of thoracic diseases, 1988, Volume: 54, Issue:2

    Topics: Aged; Clinical Trials as Topic; Dyspnea; Female; Humans; Hypertension, Pulmonary; Lung Diseases, Obs

1988
Long-term treatment of chronic obstructive lung disease by Nifedipine: an 18-month haemodynamic study.
    The European respiratory journal, 1988, Volume: 1, Issue:8

    Topics: Clinical Trials as Topic; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Lung Diseases, Obst

1988
[Use of foridon in the treatment of arterial hypertension and hypertension of the lesser circulation].
    Kardiologiia, 1988, Volume: 28, Issue:12

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Clonidine; Drug Syne

1988
[Long-term use of the calcium antagonist nifedipine (corinfar) in the treatment of patients with primary pulmonary hypertension].
    Kardiologiia, 1988, Volume: 28, Issue:4

    Topics: Adolescent; Adult; Antihypertensive Agents; Clinical Trials as Topic; Dose-Response Relationship, Dr

1988
Treatment of pulmonary hypertension with diltiazem in a child with bronchopulmonary dysplasia.
    The Canadian journal of cardiology, 1988, Volume: 4, Issue:4

    Topics: Albuterol; Bronchopulmonary Dysplasia; Child, Preschool; Diltiazem; Humans; Hydralazine; Hypertensio

1988
Nifedipine attenuates acute hypoxic pulmonary vasoconstriction in patients with chronic obstructive pulmonary disease.
    Respiration; international review of thoracic diseases, 1987, Volume: 52, Issue:2

    Topics: Aged; Cardiac Output; Female; Humans; Hypertension, Pulmonary; Lung Diseases, Obstructive; Male; Mid

1987

Other Studies

215 other studies available for nifedipine and Hypertension, Pulmonary

ArticleYear
Development of controlled release inhalable polymeric microspheres for treatment of pulmonary hypertension.
    International journal of pharmaceutics, 2013, Jun-25, Volume: 450, Issue:1-2

    Topics: Administration, Inhalation; Cell Line, Tumor; Cell Survival; Delayed-Action Preparations; Humans; Hy

2013
Upregulated expression of STIM2, TRPC6, and Orai2 contributes to the transition of pulmonary arterial smooth muscle cells from a contractile to proliferative phenotype.
    American journal of physiology. Cell physiology, 2015, Apr-15, Volume: 308, Issue:8

    Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Sign

2015
Ginsenoside Rb1 attenuates agonist-induced contractile response via inhibition of store-operated calcium entry in pulmonary arteries of normal and pulmonary hypertensive rats.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2015, Volume: 35, Issue:4

    Topics: Animals; Calcium; Calcium Channels; Cell Hypoxia; Cells, Cultured; Disease Models, Animal; Endotheli

2015
Treatment and survival in children with pulmonary arterial hypertension: the UK Pulmonary Hypertension Service for Children 2001-2006.
    Heart (British Cardiac Society), 2009, Volume: 95, Issue:4

    Topics: Adolescent; Bosentan; Case-Control Studies; Child; Child, Preschool; Epoprostenol; Female; Heart Def

2009
CPU0213, a non-selective ETA/ETB receptor antagonist, improves pulmonary arteriolar remodeling of monocrotaline-induced pulmonary hypertension in rats.
    Clinical and experimental pharmacology & physiology, 2009, Volume: 36, Issue:2

    Topics: Animals; Arterioles; Calcium Channel Blockers; Disease Models, Animal; Endothelin A Receptor Antagon

2009
Nifedipine nanoparticle agglomeration as a dry powder aerosol formulation strategy.
    International journal of pharmaceutics, 2009, Mar-18, Volume: 369, Issue:1-2

    Topics: Aerosols; Calcium Channel Blockers; Colloids; Drug Delivery Systems; Drug Stability; Hypertension, P

2009
Signalling pathways involved in the contractile response to 5-HT in the human pulmonary artery.
    The European respiratory journal, 2009, Volume: 34, Issue:6

    Topics: Aged; Calcium; Escin; Female; Humans; Hypertension, Pulmonary; Male; Middle Aged; Muscle Contraction

2009
Losartan and nifedipine therapy in patients with secondary pulmonary hypertension.
    Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2010, Volume: 10, Issue:1

    Topics: Anti-Arrhythmia Agents; Blood Pressure; Endothelium, Vascular; Humans; Hypertension, Pulmonary; Losa

2010
High-altitude pulmonary hypertension is associated with a free radical-mediated reduction in pulmonary nitric oxide bioavailability.
    The Journal of physiology, 2010, Dec-01, Volume: 588, Issue:Pt 23

    Topics: Adult; Altitude Sickness; Antihypertensive Agents; Female; Free Radicals; Hemodynamics; Humans; Hype

2010
[Hemodynamic effects of aminophylline and nifedipine in patients with high altitude pulmonary edema].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2004, Volume: 20, Issue:1

    Topics: Adult; Altitude; Altitude Sickness; Aminophylline; Humans; Hypertension, Pulmonary; Male; Nifedipine

2004
Endothelin receptor expression in idiopathic pulmonary arterial hypertension: effect of bosentan and epoprostenol treatment.
    The European respiratory journal, 2011, Volume: 38, Issue:4

    Topics: Adolescent; Antihypertensive Agents; Bosentan; Child; Child, Preschool; Drug Therapy, Combination; E

2011
Nifedipine for the treatment of high altitude pulmonary edema.
    Wilderness & environmental medicine, 2012, Volume: 23, Issue:1

    Topics: Adaptation, Physiological; Adult; Altitude Sickness; Bed Rest; Calcium Channel Blockers; Cross-Secti

2012
Nifedipine inhibits hypoxia induced transvascular leakage through down regulation of NFkB.
    Respiratory physiology & neurobiology, 2012, Jul-31, Volume: 183, Issue:1

    Topics: Altitude Sickness; Animals; Calcium Channel Blockers; Capillary Permeability; Disease Models, Animal

2012
Increased TMEM16A-encoded calcium-activated chloride channel activity is associated with pulmonary hypertension.
    American journal of physiology. Cell physiology, 2012, Dec-15, Volume: 303, Issue:12

    Topics: Animals; Anoctamin-1; Calcium Channel Blockers; Chloride Channel Agonists; Chloride Channels; Cycloo

2012
Management of high altitude pulmonary edema in the Himalaya: a review of 56 cases presenting at Pheriche medical aid post (4240 m).
    Wilderness & environmental medicine, 2013, Volume: 24, Issue:1

    Topics: Acetazolamide; Altitude Sickness; Dexamethasone; Emergency Treatment; Female; Humans; Hypertension,

2013
Dihydropyridine Ca(2+) channel blockers increase cytosolic [Ca(2+)] by activating Ca(2+)-sensing receptors in pulmonary arterial smooth muscle cells.
    Circulation research, 2013, Feb-15, Volume: 112, Issue:4

    Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Cells, Cultured; Cyt

2013
Rho/Rho kinase signaling mediates increased basal pulmonary vascular tone in chronically hypoxic rats.
    American journal of physiology. Lung cellular and molecular physiology, 2004, Volume: 287, Issue:4

    Topics: Amides; Animals; Blood Pressure; Chromones; Enzyme Inhibitors; Hypertension, Pulmonary; Hypoxia; Ind

2004
[Pulmonary arterial hypertension treated with prostacyclin or calcium blockers].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2003, Dec-04, Volume: 123, Issue:23

    Topics: Administration, Oral; Adult; Antihypertensive Agents; Calcium Channel Blockers; Epoprostenol; Female

2003
Chloride channels and alpha1-adrenoceptor-mediated pulmonary artery smooth muscle contraction: effect of pulmonary hypertension.
    European journal of pharmacology, 2004, Dec-15, Volume: 506, Issue:2

    Topics: Animals; Bumetanide; Calcium Channel Blockers; Chloride Channels; Chloride-Bicarbonate Antiporters;

2004
[Pulmonary hypertension in hereditary haemorrhagic teleangiectasia (Rendu-Osler-Weber disease). Progression over 10 years].
    Deutsche medizinische Wochenschrift (1946), 2005, Jun-10, Volume: 130, Issue:23

    Topics: Anticoagulants; Antihypertensive Agents; Bosentan; Calcium Channel Blockers; Diuretics; Endothelin R

2005
CPU0507, an endothelin receptor antagonist, improves rat hypoxic pulmonary artery hypertension and constriction in vivo and in vitro.
    Clinical and experimental pharmacology & physiology, 2006, Volume: 33, Issue:11

    Topics: Animals; Antihypertensive Agents; Endothelin Receptor Antagonists; Heart; Hypertension, Pulmonary; H

2006
Inhaled nitric oxide and oral nifedipine in a preterm infant with bronchopulmonary dysplasia and pulmonary hypertension.
    European journal of pediatrics, 2007, Volume: 166, Issue:7

    Topics: Administration, Inhalation; Administration, Oral; Bronchodilator Agents; Bronchopulmonary Dysplasia;

2007
Comparison of nifedipine and captopril in children with pulmonary hypertension due to bronchopneumonia.
    Journal of tropical pediatrics, 2008, Volume: 54, Issue:5

    Topics: Antihypertensive Agents; Blood Gas Analysis; Bronchopneumonia; Captopril; Child, Preschool; Drug The

2008
Evaluation of pulmonary artery banding in the setting of ventricular septal defects and severely elevated pulmonary vascular resistance.
    Congenital heart disease, 2006, Volume: 1, Issue:5

    Topics: Adolescent; Cardiac Catheterization; Child; Comorbidity; Constriction; Coronary Circulation; Fatal O

2006
Treatment of pulmonary hypertension in chronic bronchitis and emphysema.
    British medical journal (Clinical research ed.), 1984, Nov-24, Volume: 289, Issue:6456

    Topics: Adrenergic beta-Agonists; Almitrine; Bronchitis; Humans; Hypertension, Pulmonary; Nifedipine; Pipera

1984
Nifedipine in the treatment of primary pulmonary hypertension.
    American heart journal, 1983, Volume: 105, Issue:4

    Topics: Adult; Cardiomegaly; Electrocardiography; Female; Humans; Hypertension, Pulmonary; Nifedipine; Physi

1983
[Chronic obstructive bronchopneumopathies. Effect of nifedipine during the exercise test].
    Presse medicale (Paris, France : 1983), 1983, Dec-03, Volume: 12, Issue:44

    Topics: Adult; Aged; Exercise Test; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Lung Diseases, Ob

1983
[Spiroergometry in patients with hypoxic pulmonary hypertension treated with Corinfar].
    Sbornik vedeckych praci Lekarske fakulty Karlovy univerzity v Hradci Kralove. Supplementum, 1984, Volume: 27, Issue:4

    Topics: Adult; Humans; Hypertension, Pulmonary; Lung Diseases, Obstructive; Male; Middle Aged; Nifedipine; O

1984
Haemodynamic effects of nifedipine, nitroglycerine and prazosin in pulmonary hypertension following ingestion of toxic oil.
    European heart journal, 1983, Volume: 4, Issue:8

    Topics: Adolescent; Adult; Child; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Male; Middle Aged;

1983
Effects of nifedipine on pulmonary arterial hypertension in patients with respiratory insufficiency without acute failure.
    Respiration; international review of thoracic diseases, 1984, Volume: 45, Issue:4

    Topics: Aged; Blood Pressure; Carbon Dioxide; Chronic Disease; Forced Expiratory Flow Rates; Heart Rate; Hum

1984
Long-term beneficial effect of nifedipine in primary pulmonary hypertension.
    American heart journal, 1984, Volume: 108, Issue:2

    Topics: Adult; Blood Pressure; Cardiac Output; Electrocardiography; Humans; Hypertension, Pulmonary; Male; N

1984
Hemodynamic effects of nifedipine versus hydralazine in primary pulmonary hypertension.
    The American journal of cardiology, 1984, Sep-01, Volume: 54, Issue:6

    Topics: Blood Pressure; Cardiac Output; Heart Rate; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmona

1984
Adverse hemodynamic and clinical effects of calcium channel blockade in pulmonary hypertension secondary to obliterative pulmonary vascular disease.
    Journal of the American College of Cardiology, 1984, Volume: 4, Issue:5

    Topics: Adult; Calcium Channel Blockers; Cardiac Output; Exercise Test; Female; Hemodynamics; Humans; Hydral

1984
[Gingival hyperplasia: a possible side effect of nifedipine].
    Nederlands tijdschrift voor geneeskunde, 1984, Oct-13, Volume: 128, Issue:41

    Topics: Adult; Female; Gingival Hyperplasia; Humans; Hypertension, Pulmonary; Nifedipine

1984
The effect of calcium antagonists on hypoxic pulmonary hypertension in the piglet.
    Pediatric research, 1984, Volume: 18, Issue:12

    Topics: Animals; Animals, Newborn; Cardiac Output; Hypertension, Pulmonary; Hypoxia; Nifedipine; Pulmonary W

1984
Comparative effects of nifedipine, verapamil, and diltiazem on experimental pulmonary hypertension.
    The American journal of cardiology, 1983, Jan-01, Volume: 51, Issue:1

    Topics: Animals; Benzazepines; Blood Pressure; Cardiac Output; Diltiazem; Dinoprost; Dogs; Dose-Response Rel

1983
Treatment of primary pulmonary hypertension with nifedipine. A hemodynamic and scintigraphic evaluation.
    Annals of internal medicine, 1983, Volume: 99, Issue:4

    Topics: Adolescent; Adult; Aorta; Blood Pressure; Cardiac Output; Female; Heart Rate; Humans; Hypertension,

1983
Comparative actions of hydralazine, nifedipine and amrinone in primary pulmonary hypertension.
    The American journal of cardiology, 1983, Nov-01, Volume: 52, Issue:8

    Topics: Adult; Aminopyridines; Amrinone; Cardiac Catheterization; Cardiac Output; Female; Humans; Hydralazin

1983
[Effect of nifedipine on hemodynamics in precapillary pulmonary hypertension at rest and during exertion].
    Deutsche medizinische Wochenschrift (1946), 1983, Nov-25, Volume: 108, Issue:47

    Topics: Adult; Blood Pressure; Female; Heart Rate; Hemodynamics; Humans; Hydrogen-Ion Concentration; Hyperte

1983
Primary pulmonary hypertension, nifedipine, and hypoxemia.
    Annals of internal medicine, 1984, Volume: 100, Issue:1

    Topics: Female; Humans; Hypertension, Pulmonary; Nifedipine; Oxygen

1984
Nifedipine and pulmonary hypertension.
    Annals of internal medicine, 1984, Volume: 100, Issue:2

    Topics: Humans; Hypertension, Pulmonary; Lung; Nifedipine; Vascular Resistance

1984
Nifedipine and primary pulmonary hypertension.
    Annals of internal medicine, 1984, Volume: 100, Issue:3

    Topics: Hemodynamics; Humans; Hypertension, Pulmonary; Nifedipine

1984
Nifedipine inhibits hypoxic pulmonary vasoconstriction during rest and exercise in patients with chronic obstructive pulmonary disease. A controlled double-blind study.
    The American review of respiratory disease, 1984, Volume: 129, Issue:4

    Topics: Aged; Double-Blind Method; Hemodynamics; Humans; Hypertension, Pulmonary; Lung Diseases, Obstructive

1984
Nifedipine in primary pulmonary hypertension.
    Journal of the American College of Cardiology, 1984, Volume: 3, Issue:6

    Topics: Adult; Dose-Response Relationship, Drug; Female; Humans; Hypertension, Pulmonary; Nifedipine; Pulmon

1984
Felodipine in primary pulmonary hypertension. Report of two cases.
    Acta medica Scandinavica, 1984, Volume: 215, Issue:3

    Topics: Adult; Antihypertensive Agents; Felodipine; Female; Hemodynamics; Humans; Hypertension, Pulmonary; N

1984
Hemodynamic effects of nifedipine at rest and during exercise in primary pulmonary hypertension.
    Chest, 1984, Volume: 86, Issue:1

    Topics: Adolescent; Adult; Aged; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Male; Middle Aged; N

1984
Prevention and reversal of hypoxic pulmonary hypertension by calcium antagonists.
    The American review of respiratory disease, 1984, Volume: 130, Issue:1

    Topics: Animals; Dimethyl Sulfoxide; Hydralazine; Hypertension, Pulmonary; Hypoxia; Male; Nifedipine; Pulmon

1984
Effects of nifedipine on ventilation/perfusion matching in primary pulmonary hypertension.
    Chest, 1983, Volume: 83, Issue:2

    Topics: Female; Humans; Hypertension, Pulmonary; Middle Aged; Nifedipine; Pyridines; Ventilation-Perfusion R

1983
Sustained beneficial effect of nifedipine in primary pulmonary hypertension.
    American heart journal, 1983, Volume: 105, Issue:2

    Topics: Adult; Female; Humans; Hypertension, Pulmonary; Nifedipine; Pyridines

1983
Fatal outcome following nifedipine for pulmonary hypertension.
    Chest, 1983, Volume: 83, Issue:4

    Topics: Calcium Channel Blockers; Heart Arrest; Humans; Hypertension, Pulmonary; Male; Middle Aged; Nifedipi

1983
Calcium antagonists in heart failure.
    Herz, 1983, Volume: 8, Issue:2

    Topics: Aortic Valve Insufficiency; Calcium Channel Blockers; Coronary Disease; Diltiazem; Heart Failure; He

1983
Hemodynamic effects of nifedipine in primary pulmonary hypertension.
    Journal of the American College of Cardiology, 1983, Volume: 2, Issue:1

    Topics: Adult; Exercise Test; Female; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmonary; Nifedipine

1983
Primary pulmonary hypertension improved by long-term oral administration of nifedipine.
    American heart journal, 1983, Volume: 105, Issue:6

    Topics: Administration, Oral; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Middle Aged; Nifedipine

1983
Nifedipine treatment for pulmonary hypertension in a patient with systemic sclerosis.
    Arthritis and rheumatism, 1983, Volume: 26, Issue:6

    Topics: Cardiac Catheterization; Humans; Hypertension, Pulmonary; Male; Middle Aged; Nifedipine; Pyridines;

1983
Failure of nifedipine treatment in primary pulmonary hypertension.
    British heart journal, 1982, Volume: 47, Issue:5

    Topics: Adult; Diazoxide; Female; Humans; Hypertension, Pulmonary; Nifedipine; Pyridines

1982
[Comparative effects of tolazoline and nifedipine on hypoxic pulmonary arterial hypertension in the dog (author's transl)].
    Le Poumon et le coeur, 1982, Volume: 38, Issue:1

    Topics: Animals; Dogs; Hypertension, Pulmonary; Hypoxia; Nifedipine; Pulmonary Circulation; Pyridines; Tolaz

1982
Hydralazine in pulmonary hypertension.
    The New England journal of medicine, 1982, Nov-04, Volume: 307, Issue:19

    Topics: Humans; Hydralazine; Hypertension, Pulmonary; Lung Diseases, Obstructive; Nifedipine

1982
Inhibition of hypoxic pulmonary vasoconstriction by nifedipine.
    The American journal of cardiology, 1982, Volume: 50, Issue:4

    Topics: Animals; Calcium Channel Blockers; Depression, Chemical; Dose-Response Relationship, Drug; Hypertens

1982
Rapid attenuation of response to nifedipine in primary pulmonary hypertension.
    Chest, 1982, Volume: 82, Issue:6

    Topics: Adult; Female; Humans; Hypertension, Pulmonary; Nifedipine; Pyridines; Vascular Resistance

1982
[The effect of nifedipine on pulmonary hypertension].
    Ceskoslovenska fysiologie, 1982, Volume: 31, Issue:6

    Topics: Hemodynamics; Humans; Hypertension, Pulmonary; Nifedipine; Pyridines

1982
[A case of chronic pulmonary hypertension after fenfluramine intake].
    Wiener klinische Wochenschrift, 1982, Nov-26, Volume: 94, Issue:22

    Topics: Chronic Disease; Female; Fenfluramine; Humans; Hypertension, Pulmonary; Middle Aged; Nifedipine; Obe

1982
[Use of nifedipine in primary arterial pulmonary hypertension].
    Arquivos brasileiros de cardiologia, 1982, Volume: 39, Issue:1

    Topics: Female; Hemodynamics; Humans; Hypertension, Pulmonary; Middle Aged; Nifedipine; Pyridines

1982
Hemodynamic effects of nifedipine in pulmonary hypertension.
    Giornale italiano di cardiologia, 1982, Volume: 12, Issue:7

    Topics: Adult; Aged; Cardiac Output; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Male; Middle Age

1982
Primary pulmonary hypertension: effects of nifedipine.
    British heart journal, 1981, Volume: 46, Issue:2

    Topics: Adult; Female; Heart Failure; Humans; Hypertension, Pulmonary; Nifedipine; Pyridines

1981
Primary pulmonary hypertension: effects of nifedipine.
    British heart journal, 1980, Volume: 44, Issue:3

    Topics: Adult; Diazoxide; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Nifedipine; Pulmonary Arter

1980
[Primary pulmonary arterial hypertension. Trial treatment with nifedipine, diazoxide and isoproterenol].
    La Nouvelle presse medicale, 1980, Dec-20, Volume: 9, Issue:48

    Topics: Diazoxide; Drug Therapy, Combination; Female; Humans; Hypertension, Pulmonary; Isoproterenol; Middle

1980
HA1004, an intracellular calcium antagonist, selectively attenuates pulmonary hypertension in newborn lambs.
    Journal of cardiovascular pharmacology, 1994, Volume: 23, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Animals, Newborn; Calci

1994
Raised plasma concentrations of brain natriuretic peptide in pulmonary arterial hypertension.
    Respiratory medicine, 1995, Volume: 89, Issue:6

    Topics: Female; Humans; Hypertension, Pulmonary; Middle Aged; Natriuretic Peptide, Brain; Nerve Tissue Prote

1995
[Comparative effects of calcium channel blockers and L-arginine on chronic intermittent hypoxic pulmonary hypertension in rats].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 1994, Volume: 17, Issue:6

    Topics: Animals; Arginine; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Male; Nifedipin

1994
Effect of nifedipine on pulmonary hemodynamics.
    American heart journal, 1995, Volume: 129, Issue:6

    Topics: Blood Pressure; Hemodynamics; Humans; Hypertension, Pulmonary; Hypertrophy, Left Ventricular; Nifedi

1995
Pulmonary vascular reactivity in severe pulmonary hypertension associated with mixed connective tissue disease.
    Thorax, 1995, Volume: 50, Issue:1

    Topics: Adult; Epoprostenol; Female; Humans; Hypertension, Pulmonary; Mixed Connective Tissue Disease; Nifed

1995
Primary pulmonary hypertension in pregnancy: a case report.
    American journal of obstetrics and gynecology, 1995, Volume: 172, Issue:3

    Topics: Adult; Female; Heparin, Low-Molecular-Weight; Humans; Hypertension, Pulmonary; Nifedipine; Pregnancy

1995
[Individual approach to vasodilator treatment of pulmonary hypertension in chronic bronchitis].
    Klinicheskaia meditsina, 1994, Volume: 72, Issue:6

    Topics: Adult; Aminophylline; Bronchitis; Chronic Disease; Humans; Hydralazine; Hypertension, Pulmonary; Mid

1994
Static tension is associated with increased smooth muscle cell DNA synthesis in rat pulmonary arteries.
    The American journal of physiology, 1995, Volume: 268, Issue:3 Pt 2

    Topics: Animals; Blood Pressure; Bromodeoxyuridine; Cell Division; DNA; Endothelium, Vascular; Hypertension,

1995
[Survival--a question of active treatment. High-dose calcium blockers in pulmonary hypertension].
    Lakartidningen, 1994, Jun-29, Volume: 91, Issue:26-27

    Topics: Adult; Calcium Channel Blockers; Diltiazem; Female; Humans; Hypertension, Pulmonary; Nifedipine; Pro

1994
[Effect of large doses of nifedipine on pulmonary hypertension in patients with recurrent pulmonary thromboembolism].
    Pneumonologia i alergologia polska, 1994, Volume: 62, Issue:3-4

    Topics: Adult; Hemodynamics; Humans; Hypertension, Pulmonary; Male; Middle Aged; Nifedipine; Pulmonary Embol

1994
NIP-121 is more effective than nifedipine in acutely reversing chronic pulmonary hypertension.
    Journal of applied physiology (Bethesda, Md. : 1985), 1993, Volume: 75, Issue:3

    Topics: Altitude; Animals; Chronic Disease; Glyburide; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Male;

1993
Pulmonary hypertension in systemic lupus erythematosus--treatment with high dose nifedipine therapy?
    Clinical and experimental dermatology, 1993, Volume: 18, Issue:5

    Topics: Adult; Female; Humans; Hypertension, Pulmonary; Lupus Erythematosus, Systemic; Nifedipine

1993
[Prognosis and treatment of chronic cor pulmonale].
    La Tunisie medicale, 1993, Volume: 71, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Cardiomyopathy, Restrictive; Digitalis Glycosides; Diuretics; Female

1993
Death in a patient with primary pulmonary hypertension after 20 mg of nifedipine.
    The New England journal of medicine, 1993, Sep-09, Volume: 329, Issue:11

    Topics: Adolescent; Cardiac Output; Female; Humans; Hypertension, Pulmonary; Nifedipine; Vasodilation

1993
[Effect of a single dose of nifedipine on pulmonary hypertension measured by doppler echocardiography].
    Pneumonologia i alergologia polska, 1993, Volume: 61, Issue:3-4

    Topics: Aged; Aged, 80 and over; Echocardiography, Doppler; Humans; Hypertension, Pulmonary; Middle Aged; Ni

1993
The effect of nifedipine on monocrotaline-induced pulmonary hypertension in rats.
    Acta paediatrica Japonica : Overseas edition, 1993, Volume: 35, Issue:4

    Topics: Acute Disease; Animals; Body Weight; Disease Models, Animal; Drug Evaluation, Preclinical; Heart Ven

1993
Effects of adenosine in combination with calcium channel blockers in patients with primary pulmonary hypertension.
    Journal of the American College of Cardiology, 1993, Volume: 21, Issue:2

    Topics: Adenosine; Adult; Calcium Channel Blockers; Catheterization, Swan-Ganz; Diltiazem; Drug Therapy, Com

1993
Effects of a combination therapy of anticoagulant and vasodilator on the long-term prognosis of primary pulmonary hypertension.
    Japanese circulation journal, 1993, Volume: 57, Issue:1

    Topics: Adolescent; Adult; Drug Combinations; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Isoprot

1993
Successful management of labor and delivery in primary pulmonary hypertension.
    The American journal of cardiology, 1993, May-01, Volume: 71, Issue:12

    Topics: Adenosine; Adult; Delivery, Obstetric; Female; Humans; Hypertension, Pulmonary; Nifedipine; Pregnanc

1993
The effect of nifedipine [correction of nifidipine] and cimetidine on the haemodynamics of Egyptian bilharzial pulmonary hypertension.
    Journal of the Egyptian Society of Parasitology, 1993, Volume: 23, Issue:1

    Topics: Blood Pressure; Cimetidine; Humans; Hypertension, Pulmonary; Nifedipine; Random Allocation; Schistos

1993
Serum nifedipine concentrations and response of patients with pulmonary hypertension.
    The American journal of cardiology, 1996, May-01, Volume: 77, Issue:11

    Topics: Adult; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Male; Middle Aged; Nifedipine; Vasodil

1996
Pulmonary oedema and pleural effusion in two patients with primary pulmonary hypertension treated with calcium channel blockers.
    Heart (British Cardiac Society), 1996, Volume: 75, Issue:4

    Topics: Calcium Channel Blockers; Female; Humans; Hypertension, Pulmonary; Lung; Male; Middle Aged; Nifedipi

1996
Nitric oxide and prostacyclin as test agents of vasoreactivity in severe precapillary pulmonary hypertension: predictive ability and consequences on haemodynamics and gas exchange.
    Thorax, 1997, Volume: 52, Issue:4

    Topics: Antihypertensive Agents; Calcium Channel Blockers; Epoprostenol; Hemodynamics; Humans; Hypertension,

1997
Pharmacologic modulation of pulmonary vascular permeability during air embolism.
    Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 1997,Winter, Volume: 24, Issue:4

    Topics: Animals; Capillary Permeability; Cyclooxygenase Inhibitors; Hypertension, Pulmonary; Indomethacin; I

1997
[Effect of calcium channel antagonists in primary pulmonary hypertension in association with human immunodeficiency virus infection].
    Anales de medicina interna (Madrid, Spain : 1984), 1998, Volume: 15, Issue:2

    Topics: Adult; Calcium Channel Blockers; HIV Infections; Humans; Hypertension, Pulmonary; Nifedipine

1998
Rapid recurrence of pulmonary hypertension following cessation of nifedipine.
    Postgraduate medical journal, 1998, Volume: 74, Issue:868

    Topics: Adult; Female; Humans; Hypertension, Pulmonary; Nifedipine; Recurrence; Vasodilator Agents

1998
Inhaled nitric oxide as a screening agent for safely identifying responders to oral calcium-channel blockers in primary pulmonary hypertension.
    The European respiratory journal, 1998, Volume: 12, Issue:2

    Topics: Administration, Inhalation; Administration, Oral; Calcium Channel Blockers; Diltiazem; Dose-Response

1998
Inhaled nitric oxide and heparin for infantile primary pulmonary hypertension.
    Lancet (London, England), 1998, Jun-06, Volume: 351, Issue:9117

    Topics: Drug Therapy, Combination; Heparin; Humans; Hypertension, Pulmonary; Infant; Neovascularization, Phy

1998
Inhaled nitric oxide in primary pulmonary hypertension: a safe and effective agent for predicting response to nifedipine.
    Journal of the American College of Cardiology, 1998, Volume: 32, Issue:4

    Topics: Administration, Inhalation; Administration, Oral; Calcium Channel Blockers; Female; Hemodynamics; Hu

1998
Pulmonary hypertension in high-altitude chronic hypoxia: response to nifedipine.
    The European respiratory journal, 1998, Volume: 12, Issue:5

    Topics: Adolescent; Adult; Altitude; Blood Pressure; Calcium Channel Blockers; Echocardiography, Doppler; Fe

1998
Pulmonary hypertension in pregnancy: treatment with pulmonary vasodilators.
    Obstetrics and gynecology, 1999, Volume: 93, Issue:4

    Topics: Adult; Antihypertensive Agents; Epoprostenol; Female; Humans; Hypertension, Pulmonary; Nifedipine; P

1999
Transient left ventricular failure following bilateral lung transplantation for pulmonary hypertension.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 1999, Volume: 18, Issue:4

    Topics: Adult; Alprostadil; Antihypertensive Agents; Cardiac Output, Low; Cardiotonic Agents; Catheterizatio

1999
Nifedipine inhibits pulmonary hypertension but does not prevent decreased lung eNOS in hypoxic newborn pigs.
    The American journal of physiology, 1999, Volume: 277, Issue:3

    Topics: Acetylcholine; Animals; Animals, Newborn; Blood Pressure; Calcium Channel Blockers; Hypertension, Pu

1999
Inhaled nitric oxide and nifedipine have similar effects on lung cGMP levels in rats.
    Anesthesia and analgesia, 1999, Volume: 89, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Administration, Inhalation; Animals; Bronchodilator Agents; Cyclic AMP

1999
Comparison of the effects of nitric oxide, nitroprusside, and nifedipine on hemodynamics and right ventricular contractility in patients with chronic pulmonary hypertension.
    Chest, 2001, Volume: 119, Issue:1

    Topics: Administration, Inhalation; Administration, Sublingual; Adult; Aged; Female; Hemodynamics; Humans; H

2001
Upregulated TRP and enhanced capacitative Ca(2+) entry in human pulmonary artery myocytes during proliferation.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:2

    Topics: Blood Proteins; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell

2001
Antiphospholipid syndrome presenting as portopulmonary hypertension.
    Journal of clinical gastroenterology, 2001, Volume: 32, Issue:4

    Topics: Adult; Antiphospholipid Syndrome; Calcium Channel Blockers; Female; Humans; Hypertension, Portal; Hy

2001
Beneficial effects on skeletal muscle of the angiotensin II type 1 receptor blocker irbesartan in experimental heart failure.
    Circulation, 2001, May-01, Volume: 103, Issue:17

    Topics: Angiotensin II; Animals; Apoptosis; Biphenyl Compounds; Calcium Channel Blockers; Drug Evaluation, P

2001
Comparative effects of beraprost, a stable analogue of prostacyclin, with PGE(1), nitroglycerin and nifedipine on canine model of vasoconstrictive pulmonary hypertension.
    Prostaglandins, leukotrienes, and essential fatty acids, 2001, Volume: 64, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alprostadil; Animals; Antihypert

2001
Oxygen desaturation on the six-minute walk test and mortality in untreated primary pulmonary hypertension.
    The European respiratory journal, 2001, Volume: 17, Issue:4

    Topics: Adult; Aged; Antihypertensive Agents; Epoprostenol; Exercise Test; Female; Follow-Up Studies; Humans

2001
Rapid regression of primary pulmonary hypertension.
    Heart (British Cardiac Society), 2001, Volume: 86, Issue:1

    Topics: Calcium Channel Blockers; Cardiac Catheterization; Combined Modality Therapy; Echocardiography; Fema

2001
[Short-term effects of Angelica sinensis and nifedipine on chronic obstructive pulmonary disease in patients with pulmonary hypertension].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1992, Volume: 12, Issue:12

    Topics: Aged; Cardiac Output; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Hemodynamics; Humans

1992
Long-term hemodynamic effects of nifedipine on congenital heart disease with Eisenmenger's mechanism in children.
    Cardiovascular drugs and therapy, 1992, Volume: 6, Issue:2

    Topics: Child; Child, Preschool; Down Syndrome; Eisenmenger Complex; Heart Septal Defects; Hemodynamics; Hum

1992
[Analysis of natural history and long-term follow-up of 59 patients with obliterative pulmonary hypertension (OPH)].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1992, Volume: 14, Issue:4

    Topics: Adolescent; Adult; Child; Child, Preschool; China; Female; Follow-Up Studies; Humans; Hypertension,

1992
Short- and long-term hemodynamic effects of oral nifedipine in patients with pulmonary hypertension secondary to COPD and lung fibrosis. Deleterious effects in patients with restrictive disease.
    Chest, 1992, Volume: 102, Issue:3

    Topics: Aged; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Lung Diseases, Obstructive; Male; Middl

1992
Comparison of the effects of adenosine and nifedipine in pulmonary hypertension.
    Journal of the American College of Cardiology, 1992, Volume: 19, Issue:5

    Topics: Adenosine; Adult; Blood Pressure; Cardiac Output; Dose-Response Relationship, Drug; Female; Humans;

1992
Successful treatment of acute postoperative pulmonary hypertension with nifedipine.
    The Annals of thoracic surgery, 1992, Volume: 53, Issue:1

    Topics: Humans; Hypertension, Pulmonary; Infant; Male; Nifedipine; Postoperative Complications; Truncus Arte

1992
Acute and long-term effects of nifedipine on pulmonary and systemic hemodynamics in patients with pulmonary hypertension associated with diffuse systemic sclerosis, the CREST syndrome and mixed connective tissue disease.
    The American journal of cardiology, 1991, Dec-15, Volume: 68, Issue:17

    Topics: Adult; Blood Pressure; Calcinosis; Cardiac Catheterization; Cardiac Output; Dyspnea; Esophageal Moti

1991
[Verapamil and nifedipine limit hemodynamic changes in pulmonary circulation in rats with hypoxia].
    Kardiologia polska, 1991, Volume: 35, Issue:12

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Depression, Chemical; Disease Models, Animal; Hype

1991
[Treatment of primary pulmonary hypertension with high doses of nifedipine controlled by Doppler echocardiography].
    Pneumonologia i alergologia polska, 1991, Volume: 59, Issue:5-6

    Topics: Administration, Oral; Adult; Antihypertensive Agents; Blood Pressure; Drug Monitoring; Echocardiogra

1991
Acute nonhemodynamic pulmonary edema with nifedipine in primary pulmonary hypertension.
    Chest, 1991, Volume: 100, Issue:2

    Topics: Acute Disease; Adult; Blood Pressure; Humans; Hypertension, Pulmonary; Male; Nifedipine; Pulmonary A

1991
[Pulmonary hemodynamics in patients with hypertension during acute drug tests using obsidan and corinfar].
    Kardiologiia, 1991, Volume: 31, Issue:3

    Topics: Adult; Female; Hemodynamics; Humans; Hypertension; Hypertension, Pulmonary; Male; Middle Aged; Nifed

1991
[Pulsed Doppler echocardiography assessment of acute hemodynamic effects of nifedipine on pulmonary hypertension in chronic obstructive lung disease].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 1991, Volume: 14, Issue:2

    Topics: Administration, Sublingual; Adult; Aged; Blood Pressure; Echocardiography, Doppler; Female; Hemodyna

1991
The treatment of primary pulmonary hypertension.
    British heart journal, 1991, Volume: 66, Issue:2

    Topics: Arteritis; Humans; Hypertension, Pulmonary; Lung; Nifedipine; Survival Rate; Vasoconstriction; Vasod

1991
Pharmacokinetics and pharmacodynamics of nifedipine in children with bronchopulmonary dysplasia and pulmonary hypertension.
    Pediatric research, 1991, Volume: 29, Issue:5

    Topics: Administration, Oral; Bronchopulmonary Dysplasia; Child, Preschool; Diuretics; Female; Hemodynamics;

1991
Decrease in pulmonary artery pressure with slow release nifedipine in Saudi patients with primary pulmonary hypertension.
    Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 1991, Volume: 10, Issue:5

    Topics: Adolescent; Adult; Blood Pressure; Clinical Protocols; Delayed-Action Preparations; Female; Humans;

1991
[Effects of nifedipine on pulmonary hypertension in patients with chronic obstructive pulmonary diseases--a comparison with oxygen administration].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 1991, Volume: 14, Issue:3

    Topics: Administration, Sublingual; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Lung Diseases, Ob

1991
High dose titration of calcium channel blocking agents for primary pulmonary hypertension: guidelines for short-term drug testing.
    Journal of the American College of Cardiology, 1991, Nov-01, Volume: 18, Issue:5

    Topics: Adult; Blood Pressure; Diltiazem; Drug Administration Schedule; Drug Evaluation; Female; Hemodynamic

1991
[Comparative study of acute and chronic effects of nifedipine in patients with secondary pulmonary hypertension].
    Kardiologia polska, 1991, Volume: 34, Issue:5

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension, Pulmonary; Male; Middl

1991
Hemodynamic profiles of prostaglandin E1, isoproterenol, prostacyclin, and nifedipine in experimental porcine pulmonary hypertension.
    Critical care medicine, 1991, Volume: 19, Issue:1

    Topics: Alprostadil; Animals; Blood Pressure; Cardiac Output; Epoprostenol; Heart Rate; Hemodynamics; Hypert

1991
Experience with long-term nifedipine therapy in paediatric cardiological patients.
    Padiatrie und Padologie, 1990, Volume: 25, Issue:3

    Topics: Adolescent; Child; Child, Preschool; Dose-Response Relationship, Drug; Follow-Up Studies; Heart Defe

1990
The influence of nifedipine (Corinfar) on pulmonary hypertension in chronic obstructive lung disease.
    Zeitschrift fur Erkrankungen der Atmungsorgane, 1990, Volume: 175, Issue:3

    Topics: Adolescent; Adult; Aged; Female; Humans; Hypertension, Pulmonary; Long-Term Care; Lung Diseases, Obs

1990
Differential therapy with calcium antagonists in pulmonary hypertension secondary to COPD. Hemodynamic effects of nifedipine, diltiazem, and verapamil.
    Chest, 1990, Volume: 98, Issue:4

    Topics: Calcium Channel Blockers; Diltiazem; Exercise Test; Hemodynamics; Humans; Hypertension, Pulmonary; L

1990
Hemodynamic effects of diltiazem during vasoconstrictor pulmonary hypertension in sheep.
    Anesthesia and analgesia, 1990, Volume: 71, Issue:5

    Topics: Alprostadil; Animals; Diltiazem; Hemodynamics; Hypertension, Pulmonary; Male; Nifedipine; Sheep; Vas

1990
[A case of primary pulmonary hypertension with high venous thromboxane B2 concentration].
    Nihon Kyobu Shikkan Gakkai zasshi, 1990, Volume: 28, Issue:10

    Topics: Adult; Cold Temperature; Hemodynamics; Humans; Hypertension, Pulmonary; Male; Nifedipine; Oxygen Inh

1990
[Evaluation of the effects of vasodilator therapy in primary pulmonary hypertension. Experience in 7 cases].
    Giornale italiano di cardiologia, 1990, Volume: 20, Issue:2

    Topics: Adolescent; Adult; Aged; Biopsy; Blood Pressure; Calcium Channel Blockers; Drug Evaluation; Female;

1990
[Interactions of theophylline and nifedipine].
    Zeitschrift fur Erkrankungen der Atmungsorgane, 1990, Volume: 174, Issue:2

    Topics: Adult; Delayed-Action Preparations; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hy

1990
Nifedipine and prazosin in the management of pulmonary hypertension in CREST syndrome.
    Chest, 1990, Volume: 98, Issue:3

    Topics: Adult; Drug Therapy, Combination; Esophageal Motility Disorders; Hemodynamics; Humans; Hypertension,

1990
[Hemodynamic effects of nifedipine on pulmonary hypertension secondary to congenital heart disease with shunts].
    Zhonghua xin xue guan bing za zhi, 1990, Volume: 18, Issue:1

    Topics: Adolescent; Adult; Child; Ductus Arteriosus, Patent; Female; Heart Septal Defects, Ventricular; Hemo

1990
Severe pulmonary hypertension in a patient with Whipple's disease.
    The American journal of medicine, 1985, Volume: 79, Issue:2

    Topics: Drug Combinations; Furosemide; Heart Failure; Heart Murmurs; Humans; Hypertension, Pulmonary; Male;

1985
[Nifedipine in primary pulmonary hypertension while waiting for heart-lung transplantation].
    Ugeskrift for laeger, 1989, Aug-14, Volume: 151, Issue:33

    Topics: Adult; Female; Heart Transplantation; Heart-Lung Transplantation; Humans; Hypertension, Pulmonary; L

1989
[Primary pulmonary hypertension: physiopathology and critical evaluation of the therapy].
    La Clinica terapeutica, 1989, Feb-28, Volume: 128, Issue:4

    Topics: Blood Pressure; Captopril; Drug Evaluation; Epoprostenol; Humans; Hydralazine; Hypertension, Pulmona

1989
[The effect of calcium antagonists on pulmonary hemodynamics in patients with chronic bronchitis with manifest and latent pulmonary hypertension].
    Terapevticheskii arkhiv, 1989, Volume: 61, Issue:8

    Topics: Adult; Bronchitis; Calcium Channel Blockers; Chronic Disease; Drug Evaluation; Female; Hemodynamics;

1989
[A case of primary pulmonary hypertension with beneficial effect of oral long-acting prostaglandin E1 and nifedipine].
    Kokyu to junkan. Respiration & circulation, 1989, Volume: 37, Issue:11

    Topics: Administration, Oral; Adult; Alprostadil; Delayed-Action Preparations; Drug Evaluation; Drug Therapy

1989
Oxygen therapy and vasodilator therapy in patients with chronic lung disease: the effects of episodic pulmonary hypertension during sleep and exercise performance.
    Japanese circulation journal, 1989, Volume: 53, Issue:10

    Topics: Blood Pressure; Chronic Disease; Exercise Test; Hemodynamics; Humans; Hypertension, Pulmonary; Isoso

1989
[Therapeutic effects of nifedipine in pulmonary hypertension secondary to congenital heart disease].
    Zhonghua xin xue guan bing za zhi, 1989, Volume: 17, Issue:4

    Topics: Adolescent; Adult; Child; Ductus Arteriosus, Patent; Female; Heart Septal Defects, Ventricular; Hemo

1989
Acute effects of oxygen, nifedipine, and diltiazem in patients with cystic fibrosis and mild pulmonary hypertension.
    Pediatric pulmonology, 1989, Volume: 6, Issue:1

    Topics: Adolescent; Adult; Airway Resistance; Cystic Fibrosis; Diltiazem; Female; Hemodynamics; Humans; Hype

1989
Vasodilators and primary pulmonary hypertension. Variability of long-term response.
    Chest, 1989, Volume: 95, Issue:6

    Topics: Adult; Drug Administration Schedule; Drug Evaluation; Female; Hemodynamics; Humans; Hypertension, Pu

1989
[Value of nifedipine in respiratory failure related to obstructive chronic bronchitis during treatment over 6 months].
    Annales de cardiologie et d'angeiologie, 1989, Volume: 38, Issue:3

    Topics: Administration, Sublingual; Drug Administration Schedule; Hemodynamics; Humans; Hypertension, Pulmon

1989
Paradoxical elevation of pulmonary vascular resistance after nifedipine in primary pulmonary hypertension. A case study.
    Cor et vasa, 1989, Volume: 31, Issue:3

    Topics: Administration, Oral; Administration, Sublingual; Female; Humans; Hypertension, Pulmonary; Middle Ag

1989
[Efficacy of nifedipine on refractory hypoxemia associated with diaphragmatic hernia in the newborn infant. Apropos of a case].
    Annales de pediatrie, 1989, Volume: 36, Issue:8

    Topics: Drug Evaluation; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Hypertension, Pu

1989
Pharmacologically induced pulmonary vasodilatation in children and young adults with primary pulmonary hypertension.
    Chest, 1986, Volume: 89, Issue:4

    Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Age Factors; Blood Pressure; Calcium Channel Blocke

1986
Nifedipine reduces pulmonary pressure and vascular tone during short- but not long-term treatment of pulmonary hypertension in patients with chronic obstructive pulmonary disease.
    The American review of respiratory disease, 1989, Volume: 139, Issue:1

    Topics: Adult; Aged; Blood Pressure; Cardiac Output; Exercise Test; Female; Humans; Hypertension, Pulmonary;

1989
Comparative effects of oxygen, nifedipine and ketanserin in hypoxic pulmonary hypertension.
    Cor et vasa, 1985, Volume: 27, Issue:6

    Topics: Adult; Carbon Dioxide; Cardiac Output; Female; Heart Rate; Humans; Hypertension, Pulmonary; Hypoxia;

1985
Nitrendipine attenuates the pulmonary vascular remodeling and right ventricular hypertrophy caused by intermittent hypoxia in rats.
    The American review of respiratory disease, 1986, Volume: 133, Issue:3

    Topics: Animals; Cardiomegaly; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy; Hypoxia; Male; Muscle

1986
[Effects of nifedipine on myocardial contractility and pulmonary hypertension in hypoxic rats].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1987, Volume: 9, Issue:2

    Topics: Animals; Blood Pressure; Hematocrit; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Male; Myocardia

1987
[A case of pulmonary hypertension associated with liver cirrhosis and hepatoma].
    Kokyu to junkan. Respiration & circulation, 1985, Volume: 33, Issue:1

    Topics: Carcinoma, Hepatocellular; Humans; Hypertension, Pulmonary; Liver Cirrhosis; Liver Neoplasms; Male;

1985
The effect of nifedipine alone or combined with low dose acetylsalicyclic acid on endotoxin-induced pulmonary hypertension in the piglet.
    Intensive care medicine, 1988, Volume: 14, Issue:6

    Topics: Animals; Animals, Newborn; Aspirin; Disease Models, Animal; Drug Combinations; Drug Evaluation, Prec

1988
[Nifedipine in the treatment of chronic cor pulmonale].
    Archives des maladies du coeur et des vaisseaux, 1986, Volume: 79, Issue:1

    Topics: Adult; Aged; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Lactates; Lung Diseases, Obstruc

1986
[Vasodilator therapy in pulmonary hypertension and chronic obstructive lung disease (COPD). Hemodynamic studies exemplified by nifedipine and nitroglycerin].
    Herz, 1986, Volume: 11, Issue:4

    Topics: Exercise Test; Hemodynamics; Humans; Hypertension, Pulmonary; Long-Term Care; Lung Diseases, Obstruc

1986
[Hemodynamic studies of nifedipine (Adalat) in pulmonary hypertension in childhood].
    Wiener klinische Wochenschrift, 1986, Nov-07, Volume: 98, Issue:21

    Topics: Adolescent; Cardiac Catheterization; Child; Child, Preschool; Delayed-Action Preparations; Eisenmeng

1986
[Corrective effect of nitrates and calcium antagonists on hemodynamics and ventilation in chronic bronchitis patients with a syndrome of pulmonary hypertension].
    Terapevticheskii arkhiv, 1987, Volume: 59, Issue:3

    Topics: Bronchitis; Calcium Channel Blockers; Drug Therapy, Combination; Hemodynamics; Humans; Hypertension,

1987
[Primary pulmonary hypertension in childhood: the positive long-term therapeutic effect of nifedipine (Corinfar)].
    Kinderarztliche Praxis, 1987, Volume: 55, Issue:11

    Topics: Child, Preschool; Female; Humans; Hypertension, Pulmonary; Long-Term Care; Nifedipine; Pulmonary Wed

1987
Effect of posture, hydralazine, and nifedipine on hemodynamics, ventilation, and gas exchange in patients with chronic obstructive pulmonary disease.
    The American review of respiratory disease, 1988, Volume: 138, Issue:6

    Topics: Carbon Dioxide; Carbon Monoxide; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmonary; Lung Di

1988
Hemodynamic effects of nifedipine and oxygen in children with pulmonary hypertension.
    Cardiovascular drugs and therapy, 1988, Volume: 2, Issue:5

    Topics: Adolescent; Adult; Child; Child, Preschool; Hemodynamics; Humans; Hypertension, Pulmonary; Infant; N

1988
[Noninvasive methods for assessing the effect of nifedipine on cardiorespiratory function in a patient with cystic fibrosis].
    Praxis und Klinik der Pneumologie, 1988, Volume: 42, Issue:8

    Topics: Adult; Cystic Fibrosis; Humans; Hypertension, Pulmonary; Male; Nifedipine; Pulmonary Heart Disease;

1988
Acute hemodynamic effects of nifedipine in infants with bronchopulmonary dysplasia and pulmonary hypertension.
    Pediatric research, 1988, Volume: 24, Issue:2

    Topics: Blood Pressure; Bronchopulmonary Dysplasia; Cardiac Catheterization; Cardiac Output; Child, Preschoo

1988
Relationship between oxygen uptake and oxygen delivery in patients with pulmonary hypertension.
    The American review of respiratory disease, 1988, Volume: 138, Issue:1

    Topics: Biological Availability; Calcium Channel Blockers; Hemodynamics; Humans; Hypertension, Pulmonary; Lu

1988
[Effects of nifedipine on pulmonary hypertension in patients with chronic respiratory failure--a comparison with oxygen administration at rest and during exercise].
    Nihon Kyobu Shikkan Gakkai zasshi, 1988, Volume: 26, Issue:8

    Topics: Adolescent; Adult; Aged; Chronic Disease; Exercise; Humans; Hypertension, Pulmonary; Male; Middle Ag

1988
[Hypoxic pulmonary hypertension: nifedipine therapy].
    Cardiologia (Rome, Italy), 1988, Volume: 33, Issue:10

    Topics: Aged; Drug Evaluation; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Lung Diseases, Obstruc

1988
[Effect of a single dose of nifedipine on hemodynamic parameters of pulmonary circulation and left-ventricular function in patients with hypoxic pulmonary hypertension].
    Kardiologia polska, 1988, Volume: 31, Issue:10

    Topics: Administration, Sublingual; Adult; Aged; Female; Heart Ventricles; Hemodynamics; Humans; Hypertensio

1988
Unexplained plexogenic pulmonary arteriopathy: an unusual rapidly progressive case in childhood.
    Acta cardiologica, 1988, Volume: 43, Issue:1

    Topics: Child, Preschool; Female; Fibromuscular Dysplasia; Heart Failure; Humans; Hypertension, Pulmonary; M

1988
Hemodynamic profiles of prostaglandin E1, isoproterenol, prostacyclin, and nifedipine in vasoconstrictor pulmonary hypertension in sheep.
    Anesthesia and analgesia, 1988, Volume: 67, Issue:8

    Topics: Alprostadil; Animals; Drug Evaluation, Preclinical; Epoprostenol; Hemodynamics; Hypertension, Pulmon

1988
Prediction of favourable responses to long term vasodilator treatment of pulmonary hypertension by short term administration of epoprostenol (prostacyclin) or nifedipine.
    British heart journal, 1988, Volume: 59, Issue:6

    Topics: Administration, Oral; Administration, Sublingual; Adult; Dose-Response Relationship, Drug; Drug Admi

1988
Value and limitations of calcium channel blockade in the treatment of pulmonary hypertension associated with CREST--case reports.
    Angiology, 1988, Volume: 39, Issue:4

    Topics: Adult; Calcinosis; Diltiazem; Esophageal Diseases; Female; Humans; Hypertension, Pulmonary; Male; Mi

1988
[Effectiveness of calcium antagonists in the treatment of patients with chronic nonspecific lung diseases].
    Klinicheskaia meditsina, 1988, Volume: 66, Issue:3

    Topics: Adult; Aged; Aminophylline; Calcium Channel Blockers; Chronic Disease; Cinnarizine; Drug Evaluation;

1988
[Effect of the calcium antagonist nifedipine on central and peripheral hemodynamics in patients with primary pulmonary hypertension].
    Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR, 1988, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Male; Nifedipine; Pulmonar

1988
Acute haemodynamic effects of nifedipine in patients with ventricular septal defect.
    British heart journal, 1988, Volume: 60, Issue:2

    Topics: Adolescent; Blood Pressure; Child; Female; Heart Rate; Heart Septal Defects, Ventricular; Hemodynami

1988
[Noninvasive evaluation of the effectiveness of the treatment of primary pulmonary hypertension. Case report].
    Kardiologia polska, 1987, Volume: 30, Issue:12

    Topics: Adult; Blood Pressure; Echocardiography; Female; Humans; Hypertension, Pulmonary; Nifedipine; Pregna

1987
Acute and long term effect of nifedipine on pulmonary hypertension secondary to chronic obstructive airways disease.
    European journal of respiratory diseases. Supplement, 1986, Volume: 146

    Topics: Aged; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Lung Diseases, Obstructive; Male; Middl

1986
Thromboxane synthetase inhibition in primary pulmonary hypertension.
    Chest, 1987, Volume: 91, Issue:3

    Topics: Adult; Epoprostenol; Female; Humans; Hypertension, Pulmonary; Imidazoles; Male; Middle Aged; Nifedip

1987
[Pulmonary involvement in progressive systemic sclerosis].
    Revista medica de Chile, 1986, Volume: 114, Issue:10

    Topics: Humans; Hypertension, Pulmonary; Lung Diseases; Nifedipine; Penicillamine; Pulmonary Fibrosis; Scler

1986
[Nifedipine in the treatment of pulmonary hypertension. II--Hypoxic pulmonary hypertension].
    Arquivos brasileiros de cardiologia, 1986, Volume: 46, Issue:6

    Topics: Animals; Humans; Hypertension, Pulmonary; Hypoxia; Nifedipine; Pulmonary Artery; Rats; Vascular Resi

1986
Vasodilators in primary pulmonary hypertension: an old dilemma revisited.
    Cardiologia (Rome, Italy), 1987, Volume: 32, Issue:2

    Topics: Adult; Female; Humans; Hypertension, Pulmonary; Male; Nifedipine

1987
Hemodynamic and oxygen delivery responses to nifedipine in pulmonary hypertension secondary to chronic obstructive lung disease.
    Cardiology, 1987, Volume: 74, Issue:3

    Topics: Adult; Aged; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Lung Diseases, Obstructive; Male

1987
The value of right atrial emptying rate in predicting reduction in pulmonary artery pressure in patients with chronic obstructive pulmonary disease.
    Clinical cardiology, 1987, Volume: 10, Issue:8

    Topics: Blood Pressure; Female; Heart; Heart Atria; Humans; Hypertension, Pulmonary; Lung Diseases, Obstruct

1987
Nifedipine in pulmonary arterial hypertension. Importance of Raynaud's phenomenon.
    Chest, 1987, Volume: 92, Issue:3

    Topics: Female; Hemodynamics; Humans; Hypertension, Pulmonary; Male; Middle Aged; Nifedipine; Pulmonary Wedg

1987
Prostaglandin E1 as a screening vasodilator in primary pulmonary hypertension.
    Chest, 1987, Volume: 92, Issue:4

    Topics: Adult; Aged; Alprostadil; Female; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmonary; Male;

1987
[Effects of nifedipine on pulmonary circulation in patients with chronic cor pulmonale].
    Kokyu to junkan. Respiration & circulation, 1987, Volume: 35, Issue:7

    Topics: Adolescent; Adult; Aged; Cardiac Output; Chronic Disease; Female; Humans; Hypertension, Pulmonary; M

1987
[Hemodynamic evaluation of nifedipine in primary pulmonary hypertension--short and long term effects].
    Kokyu to junkan. Respiration & circulation, 1986, Volume: 34, Issue:2

    Topics: Adult; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Middle Aged; Nifedipine

1986
Long-term treatment with a new calcium antagonist, felodipine, in chronic obstructive lung disease.
    European journal of respiratory diseases, 1986, Volume: 68, Issue:5

    Topics: Calcium Channel Blockers; Dose-Response Relationship, Drug; Exercise Test; Felodipine; Humans; Hyper

1986
Strategy to manage pump failure due to chronic pulmonary diseases--pathophysiology and treatment of right ventricular overload.
    Japanese circulation journal, 1986, Volume: 50, Issue:4

    Topics: Alprostadil; Echocardiography; Heart; Heart Diseases; Heart Ventricles; Humans; Hypertension, Pulmon

1986
Pulmonary vascular responsiveness at rest and during exercise in idiopathic pulmonary fibrosis: effects of oxygen and nifedipine.
    Respiration; international review of thoracic diseases, 1986, Volume: 50, Issue:2

    Topics: Adult; Blood Pressure; Exercise Test; Female; Humans; Hypertension, Pulmonary; Male; Middle Aged; Ni

1986
Nifedipine in the treatment of a child with pulmonary hypertension associated with severe bronchopulmonary dysplasia.
    Clinical pediatrics, 1986, Volume: 25, Issue:4

    Topics: Bronchopulmonary Dysplasia; Hemodynamics; Humans; Hypertension, Pulmonary; Infant; Infant, Newborn;

1986
Severe pulmonary hypertension in a patient with rheumatoid arthritis--response to nifedipine.
    The Western journal of medicine, 1986, Volume: 145, Issue:2

    Topics: Arthritis, Rheumatoid; Blood Pressure; Humans; Hypertension, Pulmonary; Male; Middle Aged; Nifedipin

1986
Use of continuous-wave Doppler ultrasound to evaluate and manage primary pulmonary hypertension.
    Chest, 1986, Volume: 90, Issue:5

    Topics: Adult; Blood Pressure; Echocardiography; Female; Humans; Hypertension, Pulmonary; Nifedipine

1986
[Remote results of the successful treatment with nifedipine of 2 patients with primary pulmonary hypertension].
    Kardiologia polska, 1986, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Blood Pressure; Female; Humans; Hypertension, Pulmonary; Nifedipine; Pulmonary Ar

1986
[Primary pulmonary hypertension. A critical review of the literature and presentation of a case].
    La Clinica terapeutica, 1986, Oct-15, Volume: 119, Issue:1

    Topics: Aged; Electrocardiography; Female; Humans; Hypertension, Pulmonary; Nifedipine

1986
[Hemodynamic and gas exchange effects of nifedipine in patients with chronic pulmonary disease].
    Nihon Kyobu Shikkan Gakkai zasshi, 1986, Volume: 24, Issue:8

    Topics: Female; Hemodynamics; Hypertension, Pulmonary; Lung Diseases; Male; Nifedipine; Pulmonary Gas Exchan

1986
[Effects of oxygen and nifedipine on hemodynamics in secondary pulmonary hypertension--chronic pulmonary emphysema and chronic lung tuberculosis].
    Nihon Kyobu Shikkan Gakkai zasshi, 1986, Volume: 24, Issue:9

    Topics: Chronic Disease; Hemodynamics; Humans; Hypertension, Pulmonary; Nifedipine; Oxygen; Oxygen Consumpti

1986
Long-term favourable effect of nifedipine in primary pulmonary hypertension. Report of a case with hemodynamic evaluation after 3 and after 16 months and with clinical follow-up during 36 months.
    Giornale italiano di cardiologia, 1985, Volume: 15, Issue:11

    Topics: Adult; Cardiac Catheterization; Female; Follow-Up Studies; Hemodynamics; Humans; Hypertension, Pulmo

1985
Comparative effects of nisoldipine, nifedipine and bepridil on experimental pulmonary hypertension.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 233, Issue:1

    Topics: Animals; Bepridil; Blood Gas Analysis; Calcium Channel Blockers; Dinoprost; Dogs; Female; Hemodynami

1985
Hemodynamic effects of nifedipine on secondary pulmonary hypertension in man.
    Acta cardiologica, 1985, Volume: 40, Issue:2

    Topics: Blood Pressure; Cardiac Output; Hemodynamics; Humans; Hypertension, Pulmonary; Nifedipine; Oxygen; P

1985
Noninvasive assessment of hemodynamic improvement during chronic vasodilator therapy in obliterative pulmonary hypertension.
    The American review of respiratory disease, 1986, Volume: 133, Issue:3

    Topics: Adult; Animals; Cardiac Catheterization; Diltiazem; Exercise Test; Female; Hemodynamics; Humans; Hyp

1986
Magnitude and implications of spontaneous hemodynamic variability in primary pulmonary hypertension.
    The American journal of cardiology, 1985, Jan-01, Volume: 55, Issue:1

    Topics: Adult; Blood Pressure; Cardiac Output; Female; Hemodynamics; Humans; Hydralazine; Hypertension, Pulm

1985
Hypotension and sinus arrest with nifedipine in pulmonary hypertension.
    Chest, 1985, Volume: 87, Issue:2

    Topics: Arrhythmia, Sinus; Female; Humans; Hypertension, Pulmonary; Hypotension; Middle Aged; Nifedipine

1985
[Immediate effects of nifedipine and oxygen in acute episodes of chronic cor pulmonale].
    Medicina clinica, 1985, Feb-09, Volume: 84, Issue:5

    Topics: Adult; Aged; Humans; Hypertension, Pulmonary; Lung Diseases, Obstructive; Middle Aged; Nifedipine; O

1985
Hemodynamic effects of nifedipine in normoxic and hypoxic newborn lambs.
    Pediatric pharmacology (New York, N.Y.), 1985, Volume: 5, Issue:1

    Topics: Analysis of Variance; Animals; Animals, Newborn; Blood Gas Analysis; Blood Pressure; Disease Models,

1985
The effect of vasodilator therapy on the clinical outcome of patients with primary pulmonary hypertension.
    Circulation, 1985, Volume: 71, Issue:6

    Topics: Adolescent; Adult; Child; Female; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmonary; Male;

1985
Pulmonary edema with nifedipine in primary pulmonary hypertension.
    Respiration; international review of thoracic diseases, 1985, Volume: 47, Issue:3

    Topics: Adult; Female; Humans; Hypertension, Pulmonary; Nifedipine; Pulmonary Edema

1985
Pulmonary hypertension in systemic lupus erythematosus.
    The Journal of rheumatology, 1985, Volume: 12, Issue:2

    Topics: Adult; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension, Pulmona

1985
Calcium channel blockers in primary pulmonary hypertension.
    Chest, 1985, Volume: 88, Issue:4 Suppl

    Topics: Calcium Channel Blockers; Diltiazem; Humans; Hypertension, Pulmonary; Nifedipine; Verapamil

1985
The role of vasodilators in patients with progressive systemic sclerosis. Interstitial lung disease and pulmonary hypertension.
    Chest, 1985, Volume: 88, Issue:4 Suppl

    Topics: Humans; Hydralazine; Hypertension, Pulmonary; Lung Diseases; Nifedipine; Pulmonary Fibrosis; Sarcoid

1985
Nifedipine dilates the pulmonary vasculature without producing symptomatic systemic hypotension in upright resting and exercising patients with pulmonary hypertension secondary to chronic obstructive pulmonary disease.
    The American review of respiratory disease, 1985, Volume: 132, Issue:5

    Topics: Adult; Blood Pressure; Female; Humans; Hypertension, Pulmonary; Hypotension; Lung Diseases, Obstruct

1985
[Variable hemodynamic response to nifedipine in pulmonary hypertension secondary to chronic obstructive bronchopathy and pulmonary fibrosis].
    Schweizerische medizinische Wochenschrift, 1985, Sep-28, Volume: 115, Issue:39

    Topics: Blood Pressure; Cardiac Output; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Lung Diseases

1985
The effect of a new calcium antagonist, felodipine, on pulmonary hypertension and gas exchange in chronic obstructive lung disease.
    European journal of respiratory diseases, 1985, Volume: 67, Issue:4

    Topics: Adult; Aged; Calcium Channel Blockers; Dose-Response Relationship, Drug; Felodipine; Female; Hemodyn

1985
Two-week nifedipine treatment for pulmonary hypertension complicating chronic obstructive lung disease.
    European journal of respiratory diseases, 1985, Volume: 67, Issue:5

    Topics: Administration, Oral; Aged; Cardiac Output; Humans; Hypertension, Pulmonary; Lung Diseases, Obstruct

1985
[Vasodilator therapy in chronic thromboembolic cor pulmonare. Description of a case with unfavorable hemodynamic effects].
    Giornale italiano di cardiologia, 1985, Volume: 15, Issue:10

    Topics: Adult; Female; Heart Block; Humans; Hypertension, Pulmonary; Hypotension; Nifedipine; Pulmonary Embo

1985
Transient effect of nifedipine on pulmonary hypertension of systemic sclerosis.
    The Journal of rheumatology, 1985, Volume: 12, Issue:6

    Topics: Female; Hemodynamics; Humans; Hypertension, Pulmonary; Middle Aged; Nifedipine; Scleroderma, Systemi

1985