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nifedipine and Hyperlipidemias

nifedipine has been researched along with Hyperlipidemias in 13 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Hyperlipidemias: Conditions with excess LIPIDS in the blood.

Research Excerpts

ExcerptRelevanceReference
"Thirteen psoriatic patients with hypertension during the course of cyclosporin A therapy were treated for 25 months with a calcium channel blocker, sustained-release nifedipine, to study the clinical antihypertensive effects and adverse events during treatment with both drugs."9.08Long-term efficacy and adverse event of nifedipine sustained-release tablets for cyclosporin A-induced hypertension in patients with psoriasis. ( Furue, M; Koga, T; Nakayama, J, 1998)
"The improvement in postprandial lipidemia by nifedipine may add to its anti-atherogenic effects in hypertensive patients."6.82Nifedipine Treatment for Hypertension is Associated with Enhanced Lipolytic Activity and Accelerated Clearance of Postprandial Lipemia. ( Charach, G; Grosskopf, I; Harats, D; Kamari, Y; Shaish, A, 2016)
"Thirteen psoriatic patients with hypertension during the course of cyclosporin A therapy were treated for 25 months with a calcium channel blocker, sustained-release nifedipine, to study the clinical antihypertensive effects and adverse events during treatment with both drugs."5.08Long-term efficacy and adverse event of nifedipine sustained-release tablets for cyclosporin A-induced hypertension in patients with psoriasis. ( Furue, M; Koga, T; Nakayama, J, 1998)
"The effect of nicardipine on experimental hyperlipemia induced by a 1% cholesterol diet in spontaneously hypertensive rats (SHR) was investigated by the change of hemodynamics and the determination of lipid contents of the serum, liver, heart and aorta."3.67[Effect of nicardipine on cholesterol-fed S.H.R]. ( Kawashima, I; Nakayama, S; Ohba, T; Sakamoto, K; Tonooka, M; Yasuhara, H, 1985)
"The improvement in postprandial lipidemia by nifedipine may add to its anti-atherogenic effects in hypertensive patients."2.82Nifedipine Treatment for Hypertension is Associated with Enhanced Lipolytic Activity and Accelerated Clearance of Postprandial Lipemia. ( Charach, G; Grosskopf, I; Harats, D; Kamari, Y; Shaish, A, 2016)
"Treatment with enalapril was associated with a greater reduction in albuminuria than with nifedipine in the entire patient group, and especially in those with microalbuminuria."2.69Long-term effects of angiotensin-converting enzyme inhibition and metabolic control in hypertensive type 2 diabetic patients. ( Chan, JC; Cheung, MY; Cheung, RC; Cockram, CS; Critchley, JA; Ko, GT; Leung, DH; Nicholls, MG; So, WY; Swaminathan, R, 2000)
" doses, respectively, thereby increasing AUC0-infinity, Cmax and half-life."1.30Effects of hyperlipidemia on the pharmacokinetics of nifedipine in the rat. ( Eliot, LA; Foster, RT; Jamali, F, 1999)
"Atorvastatin treatment significantly reduced this prolongation to 46%."1.30Pharmacokinetics and pharmacodynamics of nifedipine in untreated and atorvastatin-treated hyperlipidemic rats. ( Eliot, LA; Jamali, F, 1999)
"Nifedipine treatment significantly prevented STZ-induced increase in cholesterol and triglyceride levels."1.29Effects of chronic nifedipine treatment on streptozotocin-induced diabetic rats. ( Bangaru, RA; Gandhi, TP; Goyal, RK; Satia, MC; Shah, TS, 1995)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19904 (30.77)18.7374
1990's7 (53.85)18.2507
2000's1 (7.69)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Grosskopf, I1
Shaish, A1
Charach, G1
Harats, D1
Kamari, Y1
Kobayashi, M1
Moriya, K1
Eguchi, Y1
Sugimoto, A1
Ito, S1
Ishikawa, M1
Shah, TS1
Satia, MC1
Gandhi, TP1
Bangaru, RA1
Goyal, RK1
Ariad, S1
Hechtlinger, V1
Nakayama, J1
Koga, T1
Furue, M1
Eliot, LA2
Foster, RT1
Jamali, F2
Chan, JC1
Ko, GT1
Leung, DH1
Cheung, RC1
Cheung, MY1
So, WY1
Swaminathan, R1
Nicholls, MG1
Critchley, JA1
Cockram, CS1
Duan, HW1
Zhang, YZ1
Yan, XF1
Ishikawa, Y2
Watanabe, N2
Okamoto, R2
Watanabe, Y2
Fukuzaki, H2
Ohba, T1
Tonooka, M1
Kawashima, I1
Nakayama, S1
Yasuhara, H1
Sakamoto, K1

Trials

3 trials available for nifedipine and Hyperlipidemias

ArticleYear
Nifedipine Treatment for Hypertension is Associated with Enhanced Lipolytic Activity and Accelerated Clearance of Postprandial Lipemia.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2016, Volume: 48, Issue:4

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Female; Humans; Hyperlipidemias; Hypertension;

2016
Long-term efficacy and adverse event of nifedipine sustained-release tablets for cyclosporin A-induced hypertension in patients with psoriasis.
    European journal of dermatology : EJD, 1998, Volume: 8, Issue:8

    Topics: Adult; Aged; Blood Pressure Determination; Calcium Channel Blockers; Cyclosporine; Delayed-Action Pr

1998
Long-term effects of angiotensin-converting enzyme inhibition and metabolic control in hypertensive type 2 diabetic patients.
    Kidney international, 2000, Volume: 57, Issue:2

    Topics: Aged; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Creatinine; Diabetes Mellitus, Type 2;

2000

Other Studies

10 other studies available for nifedipine and Hyperlipidemias

ArticleYear
[Effect of EG-1088, EG-626 and nifedipine on vascular lesions associated with hypertension and hyperlipidemia in stroke-prone spontaneously hypertensive rats (SHR-SP)].
    Iyo Kizai Kenkyujo hokoku. Reports of the Institute for Medical and Dental Engineering, Tokyo Medical and Dental University, 1984, Volume: 18

    Topics: Animals; Aorta; Arteries; Basilar Artery; Blood Pressure; Cerebral Arteries; Hyperlipidemias; Hypert

1984
Effects of chronic nifedipine treatment on streptozotocin-induced diabetic rats.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:1

    Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Bradycardia;

1995
Bezafibrate-induced neutropenia.
    European journal of haematology, 1993, Volume: 50, Issue:3

    Topics: Bezafibrate; Dyspnea; Female; Flushing; Humans; Hyperlipidemias; Hypertension; Leukocyte Count; Midd

1993
Effects of hyperlipidemia on the pharmacokinetics of nifedipine in the rat.
    Pharmaceutical research, 1999, Volume: 16, Issue:2

    Topics: Animals; Area Under Curve; Blood Proteins; Calcium Channel Blockers; Hyperlipidemias; Male; Nifedipi

1999
Pharmacokinetics and pharmacodynamics of nifedipine in untreated and atorvastatin-treated hyperlipidemic rats.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:1

    Topics: Animals; Anticholesteremic Agents; Atorvastatin; Blood Pressure; Calcium Channel Blockers; Cholester

1999
[Effect of high density lipoprotein (HDL) on the clearance of intracellular lipids with special reference to the co-effect of nifedipine].
    Zhonghua bing li xue za zhi = Chinese journal of pathology, 1992, Volume: 21, Issue:2

    Topics: Animals; Biological Transport, Active; Cells, Cultured; Cholesterol; Drug Synergism; Foam Cells; Hyp

1992
[Effects of nifedipine and Paeonia lactiflora on plasma TXB2 and 6-Keto-PGF1 alpha in cholesterol-fed rabbits].
    Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, 1990, Volume: 10, Issue:11

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cholesterol, Dietary; Drugs, Chinese Herbal; Hyperlipidemias;

1990
Nifedipine-suppressed atherosclerosis in cholesterol-fed rabbits but not in Watanabe heritable hyperlipidemic rabbits.
    Atherosclerosis, 1987, Volume: 64, Issue:1

    Topics: Animals; Arteriosclerosis; Cholesterol, Dietary; Hyperlipidemias; Male; Nifedipine; Rabbits

1987
Nifedipine suppressed atherosclerosis in cholesterol-fed rabbits but not in Watanabe heritable hyperlipidemic rabbits.
    Artery, 1987, Volume: 14, Issue:5

    Topics: Administration, Oral; Animals; Aorta; Arteriosclerosis; Cholesterol, Dietary; Female; Hyperlipidemia

1987
[Effect of nicardipine on cholesterol-fed S.H.R].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1985, Volume: 86, Issue:2

    Topics: Animals; Aorta; Arteriosclerosis; Body Weight; Heart Rate; Hyperlipidemias; Hypertension; Lipids; Li

1985