nifedipine has been researched along with Hypercholesterolemia in 19 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Hypercholesterolemia: A condition with abnormally high levels of CHOLESTEROL in the blood. It is defined as a cholesterol value exceeding the 95th percentile for the population.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Essential hypertension is associated with enhanced biological activity of endothelin-1 (ET-1) and impaired endothelium-dependent vasodilatation." | 9.12 | Chronic treatment with long-acting nifedipine reduces vasoconstriction to endothelin-1 in essential hypertension. ( Corti, R; Luscher, TF; Noll, G; Salvetti, A; Spieker, L; Sudano, I; Taddei, S; Virdis, A, 2007) |
| "55 g/day of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on BP and serum lipids were assessed in 18 males with hypertension (WHO stage I-II)." | 9.07 | Effects of fish oil, nifedipine and their combination on blood pressure and lipids in primary hypertension. ( Eritsland, J; Hjermann, I; Hysing, J; Landmark, K; Mundal, HH; Thaulow, E, 1993) |
| "To investigate a possible relation between hypercholesterolemia and detrusor smooth muscle function, we studied the contractile response to potassium challenge, carbachol (CCh), and the components of CCh-induced contractile mechanism in high-cholesterol diet-fed rats." | 7.78 | The effect of hypercholesterolemia on carbachol-induced contractions of the detrusor smooth muscle in rats: increased role of L-type Ca2+ channels. ( Balkanci, ZD; Bayrak, S; Erdem, A; Karabulut, I; Karaismailoğlu, S; Pehlivanoğlu, B, 2012) |
| "Essential hypertension is associated with enhanced biological activity of endothelin-1 (ET-1) and impaired endothelium-dependent vasodilatation." | 5.12 | Chronic treatment with long-acting nifedipine reduces vasoconstriction to endothelin-1 in essential hypertension. ( Corti, R; Luscher, TF; Noll, G; Salvetti, A; Spieker, L; Sudano, I; Taddei, S; Virdis, A, 2007) |
| " We studied 293 patients (below 65 years of age) under treatment with either lisinopril (n = 144) or nifedipine (n = 149) for mild to moderate hypertension for 10 weeks, and with serum cholesterol above 6." | 5.07 | Effect and tolerability of combining lovastatin with nifedipine or lisinopril. ( Bratland, B; Dahlöf, B; Gisholt, K; Os, I; Syvertsen, JO; Tretli, S, 1993) |
| "55 g/day of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on BP and serum lipids were assessed in 18 males with hypertension (WHO stage I-II)." | 5.07 | Effects of fish oil, nifedipine and their combination on blood pressure and lipids in primary hypertension. ( Eritsland, J; Hjermann, I; Hysing, J; Landmark, K; Mundal, HH; Thaulow, E, 1993) |
| "To investigate a possible relation between hypercholesterolemia and detrusor smooth muscle function, we studied the contractile response to potassium challenge, carbachol (CCh), and the components of CCh-induced contractile mechanism in high-cholesterol diet-fed rats." | 3.78 | The effect of hypercholesterolemia on carbachol-induced contractions of the detrusor smooth muscle in rats: increased role of L-type Ca2+ channels. ( Balkanci, ZD; Bayrak, S; Erdem, A; Karabulut, I; Karaismailoğlu, S; Pehlivanoğlu, B, 2012) |
| "We compared the effect of two different calcium channel blockers (CCB), Nifedipine (1,4-dihydropyridine calcium antagonist) and Diltiazem (a benzothiazepine agent) on plasma components and the development of atherosclerotic plaque in experimental hypercholesterolemia." | 3.69 | Differential effect of two calcium channel blockers--nifedipine and diltiazem--on atherogenesis in hypercholesterolemic hamster. ( Pojoga, L; Raicu, M; Simionescu, M; Simionescu, N, 1996) |
| "Hypertension and hypercholesterolemia are frequently associated, and their treatment is proven to reduce cardiovascular risk." | 2.42 | Combined antihypertensive and lipid-lowering treatment. ( Cesari, M; Pessina, AC, 2004) |
| "Nifedipine has been implicated as an inhibitor of dietary induced atherosclerosis in rabbits." | 1.27 | The beneficial influence of nifedipine on the regression of the cholesterol-induced atherosclerosis in rabbits. ( Niedmann, PD; Seidel, D; Thiery, J, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (15.79) | 18.7374 |
| 1990's | 9 (47.37) | 18.2507 |
| 2000's | 4 (21.05) | 29.6817 |
| 2010's | 3 (15.79) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Martínez-Jiménez, C | 1 |
| Cruz-Angeles, J | 1 |
| Videa, M | 1 |
| Martínez, LM | 1 |
| Navarro-Dorado, J | 1 |
| Garcia-Alonso, M | 1 |
| van Breemen, C | 1 |
| Tejerina, T | 1 |
| Fameli, N | 1 |
| Balkanci, ZD | 1 |
| Pehlivanoğlu, B | 1 |
| Bayrak, S | 1 |
| Karabulut, I | 1 |
| Karaismailoğlu, S | 1 |
| Erdem, A | 1 |
| Cesari, M | 1 |
| Pessina, AC | 1 |
| Miroshnichenko, AO | 1 |
| Liashenko, VP | 1 |
| Lukashov, SM | 1 |
| Sudano, I | 1 |
| Virdis, A | 1 |
| Taddei, S | 1 |
| Spieker, L | 1 |
| Corti, R | 1 |
| Noll, G | 1 |
| Salvetti, A | 1 |
| Luscher, TF | 1 |
| Iskenderov, BG | 1 |
| Burmistrova, LF | 1 |
| Berenshteĭn, NV | 1 |
| Lokhina, TV | 1 |
| Ohata, I | 1 |
| Sakamoto, N | 1 |
| Nagano, K | 1 |
| Maeno, H | 1 |
| Pauletto, P | 1 |
| Da Ros, S | 1 |
| Zoleo, M | 1 |
| Ragazzi, E | 1 |
| Chinellato, A | 1 |
| Pandolfo, L | 1 |
| Froldi, G | 1 |
| Caparrotta, L | 1 |
| Fassina, G | 1 |
| Os, I | 1 |
| Bratland, B | 1 |
| Dahlöf, B | 1 |
| Gisholt, K | 1 |
| Syvertsen, JO | 1 |
| Tretli, S | 1 |
| Landmark, K | 1 |
| Thaulow, E | 1 |
| Hysing, J | 1 |
| Mundal, HH | 1 |
| Eritsland, J | 1 |
| Hjermann, I | 1 |
| Raicu, M | 1 |
| Pojoga, L | 1 |
| Simionescu, N | 1 |
| Simionescu, M | 1 |
| Feuerstein, GZ | 1 |
| Fisher, M | 1 |
| Nunnart, J | 1 |
| Ruffolo, RR | 1 |
| Kato, H | 1 |
| Okada, R | 1 |
| Enoki, M | 1 |
| Oogushi, K | 1 |
| Emura, S | 1 |
| Takashima, T | 1 |
| Ohmori, K | 1 |
| Nayler, WG | 1 |
| Cohn, PF | 1 |
| Lundholm, CE | 1 |
| Sundbom, L | 1 |
| Lundholm, L | 1 |
| Thiery, J | 1 |
| Niedmann, PD | 1 |
| Seidel, D | 1 |
2 reviews available for nifedipine and Hypercholesterolemia
| Article | Year |
|---|---|
Combined antihypertensive and lipid-lowering treatment.
Topics: Anticholesteremic Agents; Antihypertensive Agents; Arteriosclerosis; Cardiovascular Diseases; Comorb | 2004 |
Impact of nifedipine on vascular smooth muscle cell differentiation. Implications for atherogenesis.
Topics: Animals; Aorta; Arteriosclerosis; Cell Differentiation; Humans; Hypercholesterolemia; Immunohistoche | 1994 |
4 trials available for nifedipine and Hypercholesterolemia
| Article | Year |
|---|---|
Chronic treatment with long-acting nifedipine reduces vasoconstriction to endothelin-1 in essential hypertension.
Topics: Acetylcholine; Adult; Brachial Artery; Calcium Channel Blockers; Delayed-Action Preparations; Dose-R | 2007 |
[Hypotensive efficacy and tolerability of combination of dihydropyridine and non-dihydropyridine calcium antagonists in the treatment of patients with arterial hypertension].
Topics: Adult; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Dihydropyridines; Dose-Response Relation | 2007 |
Effect and tolerability of combining lovastatin with nifedipine or lisinopril.
Topics: Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hypercholesterole | 1993 |
Effects of fish oil, nifedipine and their combination on blood pressure and lipids in primary hypertension.
Topics: Adult; Blood Pressure; Cholesterol; Docosahexaenoic Acids; Double-Blind Method; Drug Therapy, Combin | 1993 |
13 other studies available for nifedipine and Hypercholesterolemia
| Article | Year |
|---|---|
Co-Amorphous Simvastatin-Nifedipine with Enhanced Solubility for Possible Use in Combination Therapy of Hypertension and Hypercholesterolemia.
Topics: Anticholesteremic Agents; Antihypertensive Agents; Calorimetry, Differential Scanning; Drug Combinat | 2018 |
Calcium oscillations in human mesenteric vascular smooth muscle.
Topics: Adolescent; Adult; Aged; Aniline Compounds; Boron Compounds; Calcium Signaling; Cell Membrane; Femal | 2014 |
The effect of hypercholesterolemia on carbachol-induced contractions of the detrusor smooth muscle in rats: increased role of L-type Ca2+ channels.
Topics: Amides; Animals; Calcium Channels, L-Type; Carbachol; Cholinergic Agonists; Disease Models, Animal; | 2012 |
[Dynamics of calcium intake in the brain tissue in hypercholesterolemia].
Topics: Animals; Brain; Calcium; Cholesterol; Disease Models, Animal; Hypercholesterolemia; Nifedipine; Rats | 2004 |
Low density lipoprotein-lowering and high density lipoprotein-elevating effects of nicardipine in rats.
Topics: Acetates; Animals; Cholesterol; Clofibrate; Hypercholesterolemia; Hypolipidemic Agents; Lipoproteins | 1984 |
Effect of calcium antagonists on isolated aorta from hypercholesterolemic Yoshida rats of different ages.
Topics: Aging; Animals; Aorta, Thoracic; Dinoprostone; Hypercholesterolemia; In Vitro Techniques; Male; Musc | 1994 |
Differential effect of two calcium channel blockers--nifedipine and diltiazem--on atherogenesis in hypercholesterolemic hamster.
Topics: Animals; Aorta, Thoracic; Aortic Valve; Arteriosclerosis; Calcium Channel Blockers; Coronary Vessels | 1996 |
Carvedilol inhibits aortic lipid deposition in the hypercholesterolemic rat.
Topics: Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Arteriosclerosis; Calcium Channel Blockers; C | 1997 |
The antiatherogenic effect of nifedipine on intramural small coronary arterial lesions in cholesterol-fed rabbits.
Topics: Administration, Oral; Animals; Calcium Channel Blockers; Cholesterol; Cholesterol, Dietary; Coronary | 1998 |
Calcium, calcium antagonism, atherosclerosis, and ischemia.
Topics: Animals; Arteriosclerosis; Calcium; Coronary Disease; Cytosol; Humans; Hypercholesterolemia; Hyperte | 1992 |
Silent myocardial ischemia--classification and management.
Topics: Angina Pectoris; Atenolol; Drug Therapy, Combination; Heart Function Tests; Hemodynamics; Humans; Hy | 1990 |
Relationship between coronary atherosclerosis and "sudden cardiac death". Effects of age and calcium blockers in hypercholesterolemic mini-pigs.
Topics: Animals; Cholesterol; Coronary Artery Disease; Coronary Vessels; Death, Sudden; Female; Hypercholest | 1989 |
The beneficial influence of nifedipine on the regression of the cholesterol-induced atherosclerosis in rabbits.
Topics: Animals; Aorta; Apolipoproteins B; Arteriosclerosis; Cholesterol; Female; Hypercholesterolemia; Nife | 1987 |