Page last updated: 2024-11-01

nifedipine and Hemorrhoids

nifedipine has been researched along with Hemorrhoids in 5 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Hemorrhoids: Swollen veins in the lower part of the RECTUM or ANUS. Hemorrhoids can be inside the anus (internal), under the skin around the anus (external), or protruding from inside to outside of the anus. People with hemorrhoids may or may not exhibit symptoms which include bleeding, itching, and pain.

Research Excerpts

ExcerptRelevanceReference
" The aim was to test the efficacy of local application of nifedipine ointment in healing acute thrombosed external hemorrhoids."9.09Conservative treatment of acute thrombosed external hemorrhoids with topical nifedipine. ( Antropoli, C; Antropoli, M; De Stefano, G; Molino, D; Perrotti, P, 2001)
" The aim was to test the efficacy of local application of nifedipine ointment in healing acute thrombosed external hemorrhoids."5.09Conservative treatment of acute thrombosed external hemorrhoids with topical nifedipine. ( Antropoli, C; Antropoli, M; De Stefano, G; Molino, D; Perrotti, P, 2001)
" Serum concentrations of nifedipine and lidocaine were determined by a high-performance liquid chromatography method in order to calculate pharmacokinetic parameters."2.74Pharmacokinetics of anorectal nifedipine and lidocaine (lignocaine) ointment following haemorrhoidectomy: an open-label, single-dose, phase IV clinical study. ( Antropoli, C; Cerutti, R; Cusato, M; Dominici, P; Giannotti, G; Grossi, E; Perrotti, P; Regazzi, M, 2009)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Perrotti, P3
Dominici, P2
Grossi, E2
Antropoli, C3
Giannotti, G1
Cusato, M1
Regazzi, M1
Cerutti, R2
Thaha, MA1
Irvine, LA1
Steele, RJ1
Campbell, KL1
Chrysos, E1
Xynos, E1
Tzovaras, G1
Zoras, OJ1
Tsiaoussis, J1
Vassilakis, SJ1
Molino, D1
De Stefano, G1
Antropoli, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prospective Randomized Multi-centre Trial Comparing the Clinical Efficacy, Safety and Patient Acceptability of Circular Stapled Anopexy With Closed Diathermy Haemorrhoidectomy for Haemorrhoids[NCT00397137]182 participants (Actual)Interventional2000-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

5 trials available for nifedipine and Hemorrhoids

ArticleYear
Pharmacokinetics of anorectal nifedipine and lidocaine (lignocaine) ointment following haemorrhoidectomy: an open-label, single-dose, phase IV clinical study.
    Clinical drug investigation, 2009, Volume: 29, Issue:4

    Topics: Administration, Topical; Adult; Aged; Anal Canal; Anesthetics, Local; Area Under Curve; Blood Pressu

2009
Topical nifedipine with lidocaine ointment versus active control for pain after hemorrhoidectomy: results of a multicentre, prospective, randomized, double-blind study.
    Canadian journal of surgery. Journal canadien de chirurgie, 2010, Volume: 53, Issue:1

    Topics: Adult; Anesthetics, Local; Calcium Channel Blockers; Double-Blind Method; Drug Combinations; Female;

2010
Postdefaecation pain syndrome after circular stapled anopexy is abolished by oral nifedipine.
    The British journal of surgery, 2005, Volume: 92, Issue:2

    Topics: Adult; Defecation; Follow-Up Studies; Hemorrhoids; Humans; Male; Middle Aged; Neuromuscular Agents;

2005
Effect of nifedipine on rectoanal motility.
    Diseases of the colon and rectum, 1996, Volume: 39, Issue:2

    Topics: Administration, Sublingual; Adult; Anal Canal; Calcium Channel Blockers; Case-Control Studies; Femal

1996
Conservative treatment of acute thrombosed external hemorrhoids with topical nifedipine.
    Diseases of the colon and rectum, 2001, Volume: 44, Issue:3

    Topics: Acute Disease; Administration, Topical; Adult; Female; Hemorrhoids; Humans; Lidocaine; Male; Middle

2001