nifedipine has been researched along with Heart Diseases in 51 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Heart Diseases: Pathological conditions involving the HEART including its structural and functional abnormalities.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Benidipine treatment was associated with higher cardiovascular- and cardiac event-free rates than diltiazem treatment, and higher stroke- and ESRD-free rates than nifedipine." | 7.74 | Prognostic effects of calcium channel blockers on cardiac events, stroke and end-stage renal disease in patients with angina pectoris. Retrospective comparative study of benidipine, diltiazem and nifedipine. ( Arioka, I; Dohi, S; Sakai, K, 2008) |
| "Nifedipine and cyclosporin A (CsA) induce gingival overgrowth." | 7.71 | Macrophages and lymphocyte subpopulations in nifedipine- and cyclosporin A-associated human gingival overgrowth. ( Knuuttila, ML; Pernu, HE, 2001) |
| "The purpose of the study was to compare mitotic activity in the basal cell layer of normal human gingiva and in nifedipine- and immunosuppressive medication-induced gingival overgrowth." | 7.71 | Mitotic activity of keratinocytes in nifedipine- and immunosuppressive medication-induced gingival overgrowth. ( Knuuttila, ML; Nurmenniemi, PK; Pernu, HE, 2001) |
| " Benidipine treatment was associated with higher cardiovascular- and cardiac event-free rates than diltiazem treatment, and higher stroke- and ESRD-free rates than nifedipine." | 3.74 | Prognostic effects of calcium channel blockers on cardiac events, stroke and end-stage renal disease in patients with angina pectoris. Retrospective comparative study of benidipine, diltiazem and nifedipine. ( Arioka, I; Dohi, S; Sakai, K, 2008) |
| "The effect of nifedipine-retard (NR) (n=202) compared with that of non-CCB treatment (n=92) on the secondary prevention of myocardial infarction (MI) was retrospectively investigated in patients who had survived acute MI between 1987 and 1996." | 3.72 | Efficacy of calcium channel blocker in the secondary prevention of myocardial infarction--retrospective analysis of the 10-year prognosis or coronary thrombolysis-treated patients. ( Anazawa, T; Furuya, S; Kanmatsuse, K; Kawamata, H; Kikushima, K; Kushiro, T; Nagao, K; Sasanuma, T; Tachibana, E; Tani, S; Watanabe, I; Watanabe, K, 2004) |
| "Nifedipine and cyclosporin A (CsA) induce gingival overgrowth." | 3.71 | Macrophages and lymphocyte subpopulations in nifedipine- and cyclosporin A-associated human gingival overgrowth. ( Knuuttila, ML; Pernu, HE, 2001) |
| "The purpose of the study was to compare mitotic activity in the basal cell layer of normal human gingiva and in nifedipine- and immunosuppressive medication-induced gingival overgrowth." | 3.71 | Mitotic activity of keratinocytes in nifedipine- and immunosuppressive medication-induced gingival overgrowth. ( Knuuttila, ML; Nurmenniemi, PK; Pernu, HE, 2001) |
| "To determine whether verapamil, diltiazem, or nifedipine affect digitoxin kinetics, glycoside plasma concentrations and renal excretion were measured before and during steady-state dosing in 30 patients with cardiac insufficiency." | 2.66 | Effects of verapamil, diltiazem, and nifedipine on plasma levels and renal excretion of digitoxin. ( Kuhlmann, J, 1985) |
| "Nifedipine generally has little depressant action in this setting and usually improves cardiac function, especially if the sympathetic reflexes are intact." | 2.37 | Use of calcium antagonists in ventricular dysfunction. ( Josephson, MA; Singh, BN, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (62.75) | 18.7374 |
| 1990's | 8 (15.69) | 18.2507 |
| 2000's | 9 (17.65) | 29.6817 |
| 2010's | 2 (3.92) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jia, Y | 1 |
| Xu, J | 1 |
| Yu, Y | 1 |
| Guo, J | 1 |
| Liu, P | 1 |
| Chen, S | 1 |
| Jiang, J | 1 |
| Arioka, I | 1 |
| Dohi, S | 2 |
| Sakai, K | 1 |
| Chen, YT | 1 |
| Hsu, CI | 1 |
| Hung, DZ | 1 |
| Matsuura, I | 1 |
| Liao, JW | 1 |
| Bullon, P | 1 |
| Pugnaloni, A | 1 |
| Gallardo, I | 1 |
| Machuca, G | 1 |
| Hevia, A | 1 |
| Battino, M | 1 |
| Kharoubi, S | 1 |
| Yui, Y | 1 |
| Sumiyoshi, T | 1 |
| Kodama, K | 1 |
| Hirayama, A | 1 |
| Nonogi, H | 1 |
| Kanmatsuse, K | 2 |
| Origasa, H | 1 |
| Iimura, O | 1 |
| Ishii, M | 1 |
| Saruta, T | 1 |
| Arakawa, K | 1 |
| Hosoda, S | 1 |
| Kawai, C | 1 |
| Tani, S | 1 |
| Watanabe, I | 1 |
| Nagao, K | 1 |
| Kikushima, K | 1 |
| Watanabe, K | 1 |
| Anazawa, T | 1 |
| Kawamata, H | 1 |
| Tachibana, E | 1 |
| Furuya, S | 1 |
| Sasanuma, T | 1 |
| Kushiro, T | 1 |
| Chaudhary, KW | 1 |
| Barrezueta, NX | 1 |
| Bauchmann, MB | 1 |
| Milici, AJ | 1 |
| Beckius, G | 1 |
| Stedman, DB | 1 |
| Hambor, JE | 1 |
| Blake, WL | 1 |
| McNeish, JD | 1 |
| Bahinski, A | 1 |
| Cezar, GG | 1 |
| Opie, LH | 2 |
| Lorimer, AR | 1 |
| Tullio, D | 1 |
| Valerio, A | 1 |
| D'Agostino, F | 1 |
| Castaigne, A | 1 |
| Palsky, E | 1 |
| Benghozi, R | 1 |
| Ledouarin, B | 1 |
| Young, GP | 1 |
| Ebner, F | 1 |
| Donath, M | 1 |
| Rämsch, KD | 1 |
| Zelis, RF | 1 |
| Dipalma, JR | 1 |
| Check, WA | 1 |
| Tomoda, H | 1 |
| Ooeda, Y | 1 |
| Tagawa, R | 1 |
| Hoshiai, M | 1 |
| Furuya, H | 1 |
| Ide, M | 1 |
| Hamamoto, H | 1 |
| Resnekov, L | 1 |
| Casiglia, E | 1 |
| Spolaore, P | 1 |
| Mazza, A | 1 |
| Ginocchio, G | 1 |
| Colangeli, G | 1 |
| Onesto, C | 1 |
| Di Menza, G | 1 |
| Pegoraro, L | 1 |
| Ambrosio, GB | 1 |
| Kauder, WF | 1 |
| Watts, JA | 1 |
| Davis, WB | 1 |
| Wells, SR | 1 |
| Kuller, JA | 1 |
| Thorp, JM | 1 |
| Conlin, PR | 1 |
| Williams, GH | 1 |
| Harada, K | 1 |
| Kawahara, J | 1 |
| Okada, Y | 1 |
| Uzumaki, H | 1 |
| Kusaka, M | 1 |
| Tokiwa, T | 1 |
| Suzuki, H | 1 |
| Nakamoto, H | 1 |
| Nemoto, H | 1 |
| Sugahara, S | 1 |
| Okada, H | 1 |
| Pernu, HE | 2 |
| Knuuttila, ML | 2 |
| Nurmenniemi, PK | 1 |
| Disertori, M | 1 |
| Molinis, G | 1 |
| Antonini, L | 1 |
| Furlanello, F | 1 |
| Ripa, R | 2 |
| Ledda, F | 1 |
| Strano, A | 1 |
| Schwinger, RH | 2 |
| Böhm, M | 2 |
| Erdmann, E | 2 |
| Hollman, A | 1 |
| Broustet, JP | 1 |
| Mora, B | 1 |
| Douard, H | 1 |
| Artman, M | 1 |
| Graham, TP | 1 |
| Muiesan, G | 1 |
| Suzuki, K | 1 |
| Commerford, PJ | 1 |
| Gullace, G | 1 |
| Addamiano, P | 1 |
| Piloni, A | 1 |
| Knippel, M | 1 |
| Handa, S | 1 |
| Fujii, I | 1 |
| Ohonishi, S | 1 |
| Yamazaki, H | 1 |
| Nakamura, Y | 1 |
| Nagata, T | 1 |
| Ishida, H | 1 |
| Masuda, T | 1 |
| Kagawa, K | 1 |
| Hamasaki, A | 1 |
| Koda, N | 1 |
| Ebuchi, Y | 1 |
| Wakano, Y | 1 |
| Josephson, MA | 1 |
| Singh, BN | 1 |
| Clark, RE | 1 |
| Christlieb, IY | 1 |
| Magovern, GJ | 1 |
| Kuhlmann, J | 1 |
| Teba, L | 1 |
| Smailer, S | 1 |
| Taylor, HC | 1 |
| Kenny, J | 1 |
| Ellis, WW | 1 |
| Baer, AN | 1 |
| Robertson, RM | 1 |
| Pincus, T | 1 |
| Kronenberg, MW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00000542] | Phase 3 | 0 participants | Interventional | 1993-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 reviews available for nifedipine and Heart Diseases
| Article | Year |
|---|---|
[Calcium antagonists in cardiology].
Topics: Arrhythmias, Cardiac; Calcium Channel Blockers; Cardiomyopathy, Hypertrophic; Coronary Disease; Dilt | 1983 |
[News in cardiology].
Topics: Heart Diseases; Humans; Myocardial Infarction; Nifedipine; Sulfinpyrazone | 1983 |
Calcium channel blockers in emergency medicine.
Topics: Action Potentials; Animals; Benzazepines; Calcium; Diltiazem; Emergencies; Heart Diseases; Humans; N | 1984 |
Clinical differentiation of nifedipine and other calcium antagonists.
Topics: Biological Availability; Calcium Channel Blockers; Diltiazem; Drug Tolerance; Heart Diseases; Hemody | 1984 |
Analysis of the risks associated with calcium channel blockade: implications for the obstetrician-gynecologist.
Topics: Calcium Channel Blockers; Drug Interactions; Female; Gastrointestinal Hemorrhage; Heart Diseases; Hu | 1997 |
Use of calcium channel blockers in hypertension.
Topics: Antihypertensive Agents; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Case-Control Stud | 1998 |
[Calcium antagonists in arterial hypertension].
Topics: Calcium Channel Blockers; Diltiazem; Drug Interactions; Heart Diseases; Hemodynamics; Humans; Hypert | 1988 |
The total vascular burden, peripheral and coronary: vasodilator effects of nifedipine.
Topics: Coronary Circulation; Heart Diseases; Humans; Nifedipine; Pulmonary Circulation; Vascular Resistance | 1988 |
Use of calcium antagonists in ventricular dysfunction.
Topics: Calcium Channel Blockers; Diltiazem; Heart Diseases; Heart Ventricles; Hemodynamics; Humans; Hyperte | 1985 |
Calcium channel blocking agents and the heart.
Topics: Angina Pectoris; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Vasospasm; Digoxin; Diltia | 1985 |
5 trials available for nifedipine and Heart Diseases
| Article | Year |
|---|---|
Nifedipine retard was as effective as angiotensin converting enzyme inhibitors in preventing cardiac events in high-risk hypertensive patients with diabetes and coronary artery disease: the Japan Multicenter Investigation for Cardiovascular Diseases-B (JM
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Blood Pressure; Coronary Disease; Dia | 2004 |
Calcium antagonists: long-awaited new therapy for heart disease.
Topics: Angina Pectoris; Arrhythmias, Cardiac; Benzazepines; Calcium; Cardiomyopathies; Clinical Trials as T | 1981 |
Effect of two different therapeutic approaches on total and cardiovascular mortality in a Cardiovascular Study in the Elderly (CASTEL).
Topics: Aged; Aged, 80 and over; Atenolol; Chlorthalidone; Clonidine; Drug Therapy, Combination; Female; Hea | 1994 |
Use of nifedipine during cardiac surgery for improved myocardial protection.
Topics: Cardiac Output; Cardiac Surgical Procedures; Clinical Trials as Topic; Heart Diseases; Humans; Intra | 1985 |
Effects of verapamil, diltiazem, and nifedipine on plasma levels and renal excretion of digitoxin.
Topics: Aged; Benzazepines; Clinical Trials as Topic; Digitoxin; Diltiazem; Drug Interactions; Drug Therapy, | 1985 |
36 other studies available for nifedipine and Heart Diseases
| Article | Year |
|---|---|
Nifedipine inhibits angiotensin II-induced cardiac fibrosis via downregulating Nox4-derived ROS generation and suppressing ERK1/2, JNK signaling pathways.
Topics: Actins; Angiotensin II; Animals; Blotting, Western; Calcium Channel Blockers; Calcium Signaling; Cel | 2013 |
Prognostic effects of calcium channel blockers on cardiac events, stroke and end-stage renal disease in patients with angina pectoris. Retrospective comparative study of benidipine, diltiazem and nifedipine.
Topics: Aged; Angina Pectoris; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Female; Heart Diseases | 2008 |
Effects of chloroacetaldehyde in 2-chloroethanol-induced cardiotoxicity.
Topics: Acetaldehyde; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calmodulin; Cardiotoxins; | 2011 |
Ultrastructure of the gingiva in cardiac patients treated with or without calcium channel blockers.
Topics: Calcium Channel Blockers; Case-Control Studies; Diltiazem; Fibroblasts; Gingiva; Gingival Overgrowth | 2003 |
[Drug induced anosmia with nifedipine].
Topics: Calcium Channel Blockers; Heart Diseases; Humans; Middle Aged; Nifedipine; Olfaction Disorders | 2003 |
Efficacy of calcium channel blocker in the secondary prevention of myocardial infarction--retrospective analysis of the 10-year prognosis or coronary thrombolysis-treated patients.
Topics: Aged; Calcium Channel Blockers; Coronary Thrombosis; Female; Fibrinolytic Agents; Follow-Up Studies; | 2004 |
Embryonic stem cells in predictive cardiotoxicity: laser capture microscopy enables assay development.
Topics: Animals; Biological Assay; Biomarkers; Calcium; Cells, Cultured; Drug Evaluation, Preclinical; Fetal | 2006 |
Drugs and the heart. III. Calcium antagonists.
Topics: Angina Pectoris; Aniline Compounds; Arrhythmias, Cardiac; Calcium; Cardiomegaly; Diuretics; Heart Di | 1980 |
Calcium antagonists (calcium channel blockers).
Topics: Calcium; Calcium Channel Blockers; Heart Diseases; Humans; In Vitro Techniques; Ion Channels; Nifedi | 1981 |
Cardioprotection quo vadis? The role of nifedipine. 5-6 November 1982, Amsterdam, The Netherlands.
Topics: Animals; Calcium Channel Blockers; Coronary Disease; Heart Diseases; Humans; Nifedipine | 1983 |
Calcium antagonists and the heart.
Topics: Calcium; Heart Diseases; Humans; Nifedipine; Verapamil | 1981 |
Calcium entry blockers in cardiologic therapy.
Topics: Angina Pectoris, Variant; Calcium; Cardiovascular Agents; Diltiazem; Heart Diseases; Hemodynamics; H | 1981 |
Calcium channel blockers.
Topics: Angina Pectoris; Angina Pectoris, Variant; Arrhythmias, Cardiac; Calcium Channel Blockers; Diltiazem | 1983 |
Cineangiographic evaluation of diastolic properties of the left ventricle in man.
Topics: Adult; Blood Pressure; Cardiac Output; Cineangiography; Compliance; Diastole; Heart Diseases; Heart | 1982 |
Calcium ion blocking drugs.
Topics: Administration, Oral; Bradycardia; Calcium Channel Blockers; Diltiazem; Dizziness; Headache; Heart D | 1982 |
Antioxidant properties of dihydropyridines in isolated rat hearts.
Topics: Animals; Antioxidants; Calcium Channel Blockers; Heart; Heart Diseases; Hydrogen Peroxide; In Vitro | 1996 |
Effects of KRN4884 (a novel K+ channel opener), levcromakalim, nilvadipine and propranolol on endothelin-1-induced heart disorders in anesthetized rats.
Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Bronchoconstrictor Agents; Cromakalim; | 1998 |
Control of blood pressure and prevention of end-organ damage in patients with accelerated hypertension by combination with arotinolol and extended release nifedipine.
Topics: Adrenergic beta-Antagonists; Adult; Biopsy; Blood Pressure; Calcium Channel Blockers; Creatinine; De | 2000 |
Macrophages and lymphocyte subpopulations in nifedipine- and cyclosporin A-associated human gingival overgrowth.
Topics: Adult; Antibodies, Monoclonal; Antigens, CD; Antigens, CD20; Antigens, Differentiation, Myelomonocyt | 2001 |
Mitotic activity of keratinocytes in nifedipine- and immunosuppressive medication-induced gingival overgrowth.
Topics: Adult; Aged; Azathioprine; Calcium Channel Blockers; Cell Count; Cyclosporine; Epithelial Cells; Epi | 2001 |
[Electrophysiological effects of nifedipine in humans. Preliminary note].
Topics: Administration, Oral; Adult; Arrhythmias, Cardiac; Atrioventricular Node; Coronary Disease; Electroc | 1978 |
[Calcium antagonists in cardiologic therapy].
Topics: Calcium; Coronary Disease; Heart Diseases; Humans; Nifedipine; Pyridines; Sodium; Verapamil | 1978 |
[Calcium antagonists in cardiologic therapy].
Topics: Calcium; Coronary Disease; Heart Diseases; Humans; Myocardium; Nifedipine; Pyridines; Verapamil | 1978 |
[Pharmacological assumptions in the use of calcium antagonists].
Topics: Arrhythmias, Cardiac; Calcium; Coronary Disease; Heart Diseases; Humans; Nifedipine; Pyridines; Vera | 1978 |
[Calcium antagonists in cardiology. Introduction].
Topics: Calcium; Coronary Circulation; Heart Diseases; Humans; Myocardium; Nifedipine; Verapamil | 1978 |
Negative inotropic properties of isradipine, nifedipine, diltiazem, and verapamil in diseased human myocardial tissue.
Topics: Adult; Aged; Calcium Channel Blockers; Calcium Chloride; Diltiazem; Electric Stimulation; Female; He | 1990 |
Negative inotropic activity of the calcium antagonists isradipine, nifedipine, diltiazem, and verapamil in diseased human myocardium.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Depression, Chemical; Diltiazem; Dose-Response Re | 1991 |
Amiodarone, nifedipine, sodium cromoglycate.
Topics: Amiodarone; Cromolyn Sodium; Heart Diseases; Humans; Nifedipine; Plants, Medicinal | 1991 |
Use of drugs in cardiac rehabilitation.
Topics: Adrenergic beta-Antagonists; Amiodarone; Diltiazem; Drug Therapy, Combination; Electrocardiography; | 1986 |
Guidelines for vasodilator therapy of congestive heart failure in infants and children.
Topics: Captopril; Child; Child, Preschool; Enalapril; Heart Diseases; Heart Failure; Heart Ventricles; Hemo | 1987 |
[Quadratic analysis of left ventricular ejection phase volume using a M-mode echocardiogram, and the effects of beta-methyldigoxin, nifedipine, physical exercise and propranolol on new parameters].
Topics: Adult; Data Interpretation, Statistical; Digoxin; Echocardiography; Exercise; Female; Heart; Heart D | 1988 |
Echocardiographic evaluation of inferior vena cava wall motion and pulmonary flow velocity responses to sublingual nifedipine.
Topics: Adult; Blood Flow Velocity; Blood Pressure; Cardiac Catheterization; Echocardiography; Female; Heart | 1986 |
Strategy to manage pump failure due to chronic pulmonary diseases--pathophysiology and treatment of right ventricular overload.
Topics: Alprostadil; Echocardiography; Heart; Heart Diseases; Heart Ventricles; Humans; Hypertension, Pulmon | 1986 |
[Clinical and histopathological observations of the gingiva in heart patients treated with nifedipine--a report of 3 cases].
Topics: Gingiva; Gingival Hyperplasia; Heart Diseases; Humans; Male; Middle Aged; Nifedipine | 1985 |
Effect of nifedipine on TRH stimulation of TSH and PRL release by the pituitary gland.
Topics: Adult; Aged; Female; Heart Diseases; Humans; Hypothalamo-Hypophyseal System; Joint Diseases; Male; M | 1985 |
Left ventricular dysfunction induced by cold exposure in patients with systemic sclerosis.
Topics: Adult; Cold Temperature; Female; Heart Diseases; Heart Ventricles; Hemodynamics; Humans; Hypothermia | 1986 |