nifedipine has been researched along with Headache in 38 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Headache: The symptom of PAIN in the cranial region. It may be an isolated benign occurrence or manifestation of a wide variety of HEADACHE DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty-nine black patients with mild to moderate hypertension were treated for 1 year with various long-acting preparations of nifedipine, during which time serial changes in 24-hour ambulatory blood pressure (BP), exercise performance, left ventricular (LV) mass index and LV systolic function were evaluated." | 9.07 | Effects of long-acting nifedipine on casual office blood pressure measurements, 24-hour ambulatory blood pressure profiles, exercise parameters and left ventricular mass and function in black patients with mild to moderate systemic hypertension. ( Davis, J; Essop, MR; Middlemost, SJ; Sack, M; Sareli, P; Skoularigis, J; Wisenbaugh, T, 1992) |
| "Nicardipine and nifedipine are structurally similar dihydropyridine calcium channel blockers with demonstrated efficacy in the treatment of stable angina pectoris." | 9.06 | Randomized double-blind comparison of side effects of nicardipine and nifedipine in angina pectoris. The Nicardipine Investigators Group. ( DeWood, MA; Wolbach, RA, 1990) |
| "Nifedipine, 30 mg/day for 4 weeks, was compared to placebo in a double-blind, randomized, crossover study, as an additional drug added to the usual treatment of 14 patients with bronchial asthma." | 9.06 | Nifedipine treatment of patients with bronchial asthma. ( Dascalopoulou, E; Maniki, E; Patakas, D; Tsara, V, 1987) |
| "Nifedipine has been used in hypertension, mainly as a third-line drug for rapid blood pressure reduction, for over 10 years." | 9.06 | Is nifedipine a suitable first-line treatment for essential hypertension in general practice? ( Adams-Strump, BJ; Gaw, N; Langan, JJ; Murray, TS; Sullivan, FM, 1987) |
| "Nifedipine was administered to 21 patients with angina pectoris which was refractory to conventional medication." | 9.05 | Nifedipine in medically refractory angina pectoris. ( O'Rourke, MF; Sammel, NL, 1981) |
| "Ninety patients, 50 males and 40 females, and their ages ranged between 42 and 70 years, with severe hypertension were treated by either sublingual verapamil tablets 40 mg (30 patients) or 80 mg (30 patients) or sublingual nifedipine capsules 10 mg (30 patients)." | 7.70 | Efficacy of sublingual verapamil in patients with severe essential hypertension: comparison with sublingual nifedipine. ( Al-Waili, NS; Hasan, NA, 1999) |
| "Although nifedipine therapy resulted in substantial relief of dysphagia in six patients with diffuse esophageal spasm, significant side effects, particularly in young working subjects, precluded prolonged use." | 7.67 | Nifedipine therapy for diffuse esophageal spasm. ( Morse, J; Thomas, E; Willis, M; Witt, P, 1986) |
| " Most adverse events were mild or moderate and the investigators' overall evaluation of tolerability was excellent or good for 91% of patients." | 6.67 | A study of the efficacy and safety of amlodipine for the treatment of hypertension in general practice. ( Varrone, J, 1991) |
| " Both nisoldipine and the diuretic had a flat dose-response curve." | 6.66 | Monotherapy with the calcium channel antagonist nisoldipine for systemic hypertension and comparison with diuretic drugs. ( Daniels, AR; Opie, LH, 1987) |
| "In a multicentre crossover study of 97 patients with mild hypertension, the incidence and severity of adverse effects were observed during the first 14 days of treatment with amlodipine, nifedipine retard or placebo." | 5.07 | Early side-effects of antihypertensive therapy: comparison of amlodipine and nifedipine retard. ( Bremner, AD; Fell, PJ; Hosie, J; James, IG; Saul, PA; Taylor, SH, 1993) |
| "Thirty-nine black patients with mild to moderate hypertension were treated for 1 year with various long-acting preparations of nifedipine, during which time serial changes in 24-hour ambulatory blood pressure (BP), exercise performance, left ventricular (LV) mass index and LV systolic function were evaluated." | 5.07 | Effects of long-acting nifedipine on casual office blood pressure measurements, 24-hour ambulatory blood pressure profiles, exercise parameters and left ventricular mass and function in black patients with mild to moderate systemic hypertension. ( Davis, J; Essop, MR; Middlemost, SJ; Sack, M; Sareli, P; Skoularigis, J; Wisenbaugh, T, 1992) |
| "The effects of amlodipine on ambulatory blood pressure were investigated in patients with mild-to-moderate hypertension." | 5.07 | A double-blind evaluation of the effect of amlodipine on ambulatory blood pressure. ( Burris, JF; Klein, J; Mroczek, WJ, 1991) |
| "Nicardipine and nifedipine are structurally similar dihydropyridine calcium channel blockers with demonstrated efficacy in the treatment of stable angina pectoris." | 5.06 | Randomized double-blind comparison of side effects of nicardipine and nifedipine in angina pectoris. The Nicardipine Investigators Group. ( DeWood, MA; Wolbach, RA, 1990) |
| "Nifedipine, 30 mg/day for 4 weeks, was compared to placebo in a double-blind, randomized, crossover study, as an additional drug added to the usual treatment of 14 patients with bronchial asthma." | 5.06 | Nifedipine treatment of patients with bronchial asthma. ( Dascalopoulou, E; Maniki, E; Patakas, D; Tsara, V, 1987) |
| "Nifedipine has been used in hypertension, mainly as a third-line drug for rapid blood pressure reduction, for over 10 years." | 5.06 | Is nifedipine a suitable first-line treatment for essential hypertension in general practice? ( Adams-Strump, BJ; Gaw, N; Langan, JJ; Murray, TS; Sullivan, FM, 1987) |
| "Nifedipine was administered to 21 patients with angina pectoris which was refractory to conventional medication." | 5.05 | Nifedipine in medically refractory angina pectoris. ( O'Rourke, MF; Sammel, NL, 1981) |
| "The present evidence suggests similar efficacy between nifedipine, hydralazine and labetalol in the treatment of severe hypertension in pregnancy." | 4.98 | Drugs for treating severe hypertension in pregnancy: a network meta-analysis and trial sequential analysis of randomized clinical trials. ( Sequeira, RP; Sridharan, K, 2018) |
| "Ninety patients, 50 males and 40 females, and their ages ranged between 42 and 70 years, with severe hypertension were treated by either sublingual verapamil tablets 40 mg (30 patients) or 80 mg (30 patients) or sublingual nifedipine capsules 10 mg (30 patients)." | 3.70 | Efficacy of sublingual verapamil in patients with severe essential hypertension: comparison with sublingual nifedipine. ( Al-Waili, NS; Hasan, NA, 1999) |
| "Both the acute blood pressure lowering and renal effects of the calcium antagonist nicardipine and those after 1 week's treatment were investigated in 10 normotensive volunteers and in 10 patients with mild to moderate essential hypertension." | 3.67 | Antihypertensive and renal effects of nicardipine. ( Geyskes, GG; van Nistelrooy, AE; van Schaik, BA, 1984) |
| "Although nifedipine therapy resulted in substantial relief of dysphagia in six patients with diffuse esophageal spasm, significant side effects, particularly in young working subjects, precluded prolonged use." | 3.67 | Nifedipine therapy for diffuse esophageal spasm. ( Morse, J; Thomas, E; Willis, M; Witt, P, 1986) |
| "The objective of this study was to compare the rate and extent of nifedipine bioavailability after single dose administration of Adalat OROS 30 (Reference) and Nifedipine Sandoz retard 30 tablets (Test)." | 2.72 | Significant food interactions observed with a nifedipine modified-release formulation marketed in the European Union. ( Blume, H; Brendel, E; Schmücker, K; Schug, B; van Zwieten, PA; Wonnemann, M, 2006) |
| " Compared with placebo, barnidipine lowered blood pressure, with a trend toward a dose-response relationship over the dose range 10-30 mg." | 2.68 | Barnidipine, a novel calcium antagonist for once-daily treatment of hypertension: a multicenter, double-blind, placebo-controlled, dose-ranging study. Dutch Barnidipine Multicenter Study Group. ( Hart, W; Holwerda, NJ, 1997) |
| " Most adverse events were mild or moderate and the investigators' overall evaluation of tolerability was excellent or good for 91% of patients." | 2.67 | A study of the efficacy and safety of amlodipine for the treatment of hypertension in general practice. ( Varrone, J, 1991) |
| " Both nisoldipine and the diuretic had a flat dose-response curve." | 2.66 | Monotherapy with the calcium channel antagonist nisoldipine for systemic hypertension and comparison with diuretic drugs. ( Daniels, AR; Opie, LH, 1987) |
| " This study aimed to elucidate the impact of SMS on nifedipine/felodipine treatment by the findings from rat pharmacokinetic study of nifedipine to the retrospective cohort study of patients with hypertension." | 1.72 | Effect of repeated Shengmai-San administration on nifedipine pharmacokinetics and the risk/benefit under co-treatment. ( Chen, WC; Chia-Hui Tan, E; Chiang, TY; Shen, CC; Ueng, YF; Wang, HJ, 2022) |
| "Pregnancy was extended for more than 48 hours after the first dose of nifedipine in 86." | 1.36 | [Management of pre-term labor: use of nifedipine in Conakry, Guinea]. ( Camara, MK; Cissoko, M; Diallo, A; Diallo, FB; Diallo, MS; Diallo, Y; Lontsi, GR; Sy, T, 2010) |
| "Confusion and sleep disorders constitute 8 cases." | 1.27 | Nifedipine--a survey of adverse effects. Four years' reporting in Sweden. ( Myrhed, M; Wiholm, BE, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (50.00) | 18.7374 |
| 1990's | 10 (26.32) | 18.2507 |
| 2000's | 3 (7.89) | 29.6817 |
| 2010's | 5 (13.16) | 24.3611 |
| 2020's | 1 (2.63) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, HJ | 1 |
| Chia-Hui Tan, E | 1 |
| Chiang, TY | 1 |
| Chen, WC | 1 |
| Shen, CC | 1 |
| Ueng, YF | 1 |
| Sridharan, K | 1 |
| Sequeira, RP | 1 |
| Bain, J | 1 |
| Segal, D | 1 |
| Amin, R | 1 |
| Monoky, D | 1 |
| Thompson, SJ | 1 |
| Rezk, M | 1 |
| Sayyed, T | 1 |
| Masood, A | 1 |
| Dawood, R | 1 |
| Medhi, B | 1 |
| Rao, RS | 1 |
| Prakash, A | 1 |
| Prakash, O | 1 |
| Kaman, L | 1 |
| Pandhi, P | 1 |
| Tenney, JR | 1 |
| Schapiro, MB | 1 |
| Sy, T | 1 |
| Diallo, FB | 1 |
| Diallo, Y | 1 |
| Camara, MK | 1 |
| Diallo, A | 1 |
| Cissoko, M | 1 |
| Lontsi, GR | 1 |
| Diallo, MS | 1 |
| Wonnemann, M | 1 |
| Schug, B | 1 |
| Schmücker, K | 1 |
| Brendel, E | 1 |
| van Zwieten, PA | 1 |
| Blume, H | 1 |
| Rahn, KH | 1 |
| Peret Martínez, JJ | 1 |
| Roca-Cusachs i Coll, A | 1 |
| Monmany i Roca, J | 1 |
| Nolla i Panadès, J | 1 |
| van Schaik, BA | 1 |
| van Nistelrooy, AE | 1 |
| Geyskes, GG | 1 |
| Hill, JA | 1 |
| Feldman, RL | 1 |
| Pepine, CJ | 1 |
| Conti, CR | 1 |
| Sammel, NL | 1 |
| O'Rourke, MF | 1 |
| Bassan, M | 1 |
| Weiler-Ravell, D | 1 |
| Shalev, O | 1 |
| Resnekov, L | 1 |
| Antón Aranda, E | 1 |
| Martí Cabane, J | 1 |
| Utrilla Mínguez, R | 1 |
| Bremner, AD | 1 |
| Fell, PJ | 1 |
| Hosie, J | 1 |
| James, IG | 1 |
| Saul, PA | 1 |
| Taylor, SH | 1 |
| Golwyn, DH | 1 |
| Sevlie, CP | 1 |
| Hart, W | 1 |
| Holwerda, NJ | 1 |
| Al-Waili, NS | 1 |
| Hasan, NA | 1 |
| Pearson, ER | 1 |
| D'Souza, RJ | 1 |
| Hamilton-Wood, C | 1 |
| Nicholls, AJ | 1 |
| Beaman, M | 1 |
| Jacome, DE | 1 |
| Steinke, L | 1 |
| Kiskery, L | 1 |
| Middlemost, SJ | 1 |
| Sack, M | 1 |
| Davis, J | 1 |
| Skoularigis, J | 1 |
| Wisenbaugh, T | 1 |
| Essop, MR | 1 |
| Sareli, P | 1 |
| Mroczek, WJ | 1 |
| Burris, JF | 1 |
| Klein, J | 1 |
| Varrone, J | 1 |
| DeWood, MA | 1 |
| Wolbach, RA | 1 |
| Berman, BA | 1 |
| Ross, RN | 1 |
| Karpov, RS | 1 |
| Idrisova, EM | 1 |
| Dudko, VA | 1 |
| Shchepotin, BM | 1 |
| Miroshnik, NIu | 1 |
| Patakas, D | 1 |
| Maniki, E | 1 |
| Tsara, V | 1 |
| Dascalopoulou, E | 1 |
| Sullivan, FM | 1 |
| Murray, TS | 1 |
| Gaw, N | 1 |
| Langan, JJ | 1 |
| Adams-Strump, BJ | 1 |
| Teves, R | 1 |
| Archambeaud-Mouveroux, F | 1 |
| Morvan, C | 1 |
| Arnaud, M | 1 |
| Desproges-Gotteron, R | 1 |
| Gjørup, T | 1 |
| Kelbaek, H | 1 |
| Hartling, OJ | 1 |
| Nielsen, SL | 1 |
| Schnapp, P | 1 |
| Hermann, H | 1 |
| Cernak, P | 1 |
| Kahay, J | 1 |
| Daniels, AR | 1 |
| Opie, LH | 1 |
| Myrhed, M | 1 |
| Wiholm, BE | 1 |
| Thomas, E | 1 |
| Witt, P | 1 |
| Willis, M | 1 |
| Morse, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparative Evaluation of MEBO Ointment and Topical Diltiazem Ointment in the Treatment of Acute Anal Fissure: a Randomized Clinical Trial[NCT04153032] | Phase 2 | 183 participants (Anticipated) | Interventional | 2019-12-01 | Recruiting | ||
| Effects of Platelet-rich Plasma in the Treatment of Chronic Anal Fissure[NCT04320498] | Phase 4 | 41 participants (Actual) | Interventional | 2019-01-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for nifedipine and Headache
| Article | Year |
|---|---|
Drugs for treating severe hypertension in pregnancy: a network meta-analysis and trial sequential analysis of randomized clinical trials.
Topics: Antihypertensive Agents; Dose-Response Relationship, Drug; Female; Headache; Humans; Hydralazine; Hy | 2018 |
Recent advances in the pharmacotherapy of chronic anal fissure: an update.
Topics: Administration, Topical; Adrenergic alpha-Antagonists; Anal Canal; Botulinum Toxins; Calcium Channel | 2008 |
Recent advances in the pharmacotherapy of chronic anal fissure: an update.
Topics: Administration, Topical; Adrenergic alpha-Antagonists; Anal Canal; Botulinum Toxins; Calcium Channel | 2008 |
Recent advances in the pharmacotherapy of chronic anal fissure: an update.
Topics: Administration, Topical; Adrenergic alpha-Antagonists; Anal Canal; Botulinum Toxins; Calcium Channel | 2008 |
Recent advances in the pharmacotherapy of chronic anal fissure: an update.
Topics: Administration, Topical; Adrenergic alpha-Antagonists; Anal Canal; Botulinum Toxins; Calcium Channel | 2008 |
Treating coexisting cardiovascular and pulmonary disease with calcium antagonists.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Asthma, Exercise-Induced; Bronchial Spasm; Calcium; Ca | 1986 |
17 trials available for nifedipine and Headache
| Article | Year |
|---|---|
RETRACTED: Nicorandil vs nifedipine for the treatment of preterm labour: a randomized clinical trial.
Topics: Adolescent; Adult; Double-Blind Method; Female; Fetal Diseases; Headache; Humans; Nicorandil; Nifedi | 2015 |
Significant food interactions observed with a nifedipine modified-release formulation marketed in the European Union.
Topics: Adult; Analysis of Variance; Area Under Curve; Biological Availability; Calcium Channel Blockers; Ch | 2006 |
Randomized double-blind comparison of nifedipine and isosorbide dinitrate in patients with coronary arterial spasm.
Topics: Adult; Aged; Angina Pectoris; Angiocardiography; Clinical Trials as Topic; Coronary Vasospasm; Doubl | 1982 |
Nifedipine in medically refractory angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Angiography; Clinical Trials as Topic; Diastole; Dizziness; Female; He | 1981 |
The additive antianginal action of oral nifedipine in patients receiving propranolol: magnitude and duration of effect.
Topics: Administration, Oral; Adult; Aged; Angina Pectoris; Blood Pressure; Electrocardiography; Exercise Te | 1982 |
Early side-effects of antihypertensive therapy: comparison of amlodipine and nifedipine retard.
Topics: Adult; Aged; Amlodipine; Delayed-Action Preparations; Dizziness; Double-Blind Method; Edema; Female; | 1993 |
Barnidipine, a novel calcium antagonist for once-daily treatment of hypertension: a multicenter, double-blind, placebo-controlled, dose-ranging study. Dutch Barnidipine Multicenter Study Group.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Edema; Female; Flushing; He | 1997 |
Effects of long-acting nifedipine on casual office blood pressure measurements, 24-hour ambulatory blood pressure profiles, exercise parameters and left ventricular mass and function in black patients with mild to moderate systemic hypertension.
Topics: Adult; Ambulatory Care; Black People; Blood Pressure; Blood Pressure Determination; Circadian Rhythm | 1992 |
A double-blind evaluation of the effect of amlodipine on ambulatory blood pressure.
Topics: Adolescent; Adult; Aged; Amlodipine; Blood Pressure; Blood Pressure Determination; Calcium Channel B | 1991 |
A study of the efficacy and safety of amlodipine for the treatment of hypertension in general practice.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Calcium Channel Blockers; Edema; Female; Headache; Human | 1991 |
Randomized double-blind comparison of side effects of nicardipine and nifedipine in angina pectoris. The Nicardipine Investigators Group.
Topics: Adult; Angina Pectoris; Dizziness; Double-Blind Method; Edema; Flushing; Foot Diseases; Headache; Hu | 1990 |
[Effect of nifedipine (corinfar) on cerebrovascular circulation in patients with exertion-induced stenocardia].
Topics: Adult; Angina Pectoris; Cerebrovascular Circulation; Clinical Trials as Topic; Dose-Response Relatio | 1989 |
Nifedipine treatment of patients with bronchial asthma.
Topics: Adult; Aged; Albuterol; Asthma; Blood Pressure; Circadian Rhythm; Clinical Trials as Topic; Double-B | 1987 |
Is nifedipine a suitable first-line treatment for essential hypertension in general practice?
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; | 1987 |
Controlled double-blind trial of the clinical effect of nifedipine in the treatment of idiopathic Raynaud's phenomenon.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Drug Tolerance; Female; Headache; Humans; Male | 1986 |
Nifedipine monotherapy in the hypertensive elderly: a placebo-controlled clinical trial.
Topics: Aged; Aged, 80 and over; Blood Pressure; Clinical Trials as Topic; Delayed-Action Preparations; Edem | 1987 |
Monotherapy with the calcium channel antagonist nisoldipine for systemic hypertension and comparison with diuretic drugs.
Topics: Adult; Amiloride; Calcium Channel Blockers; Diuretics; Dose-Response Relationship, Drug; Double-Blin | 1987 |
18 other studies available for nifedipine and Headache
| Article | Year |
|---|---|
Effect of repeated Shengmai-San administration on nifedipine pharmacokinetics and the risk/benefit under co-treatment.
Topics: Animals; Cytochrome P-450 CYP3A; Drug Combinations; Drugs, Chinese Herbal; Felodipine; Headache; Hum | 2022 |
Call-Fleming syndrome: headache in a 16-year-old girl.
Topics: Adolescent; Angiography; Anxiety; Attention Deficit Disorder with Hyperactivity; Female; Headache; H | 2013 |
Child neurology: alternating hemiplegia of childhood.
Topics: Age Factors; Calcium Channel Blockers; Child, Preschool; Diagnostic Imaging; Disease Progression; DN | 2010 |
[Management of pre-term labor: use of nifedipine in Conakry, Guinea].
Topics: Apgar Score; Delivery, Obstetric; Dizziness; Female; Headache; Humans; Infant, Newborn; Nifedipine; | 2010 |
[Calcium antagonists in the therapy of hypertension].
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Diuretics; Drug Synergism; Headache; Humans; | 1984 |
[Use of sublingual nifedipine in the hypertensive crisis].
Topics: Aged; Female; Headache; Humans; Hypertension; Male; Middle Aged; Nifedipine | 1983 |
Antihypertensive and renal effects of nicardipine.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Glomerular Filtration Rate; Headache; Humans; Hyper | 1984 |
Calcium ion blocking drugs.
Topics: Administration, Oral; Bradycardia; Calcium Channel Blockers; Diltiazem; Dizziness; Headache; Heart D | 1982 |
[Doppler ultrasound in the diagnosis of ergotism].
Topics: Administration, Rectal; Adult; Cerebral Arteries; Drug Overdose; Ergotamine; Ergotism; Female; Heada | 1994 |
Monoamine oxidase inhibitor hypertensive crisis headache and orthostatic hypotension.
Topics: Administration, Sublingual; Depressive Disorder; Headache; Humans; Hypertension, Malignant; Hypotens | 1993 |
Efficacy of sublingual verapamil in patients with severe essential hypertension: comparison with sublingual nifedipine.
Topics: Administration, Sublingual; Adult; Aged; Blood Pressure; Calcium Channel Blockers; Female; Headache; | 1999 |
Hypertensive encephalopathy and nephrotic syndrome: a possible link?
Topics: Anti-Inflammatory Agents; Antihypertensive Agents; Azathioprine; Brain Diseases; Calcium Channel Blo | 1999 |
Exploding head syndrome and idiopathic stabbing headache relieved by nifedipine.
Topics: Aged; Anxiety Disorders; Calcium Channel Blockers; Calcium Channels; Diagnosis, Differential; Electr | 2001 |
[Experience with adalat, a coronary therapeutic agent in medical practice (authors transl)].
Topics: Angina Pectoris; Blood Pressure; Drug Evaluation; Female; Headache; Humans; Male; Middle Aged; Nifed | 1977 |
[Changes in cerebral circulation under the influence of korinfar in hypertension patients].
Topics: Adult; Aged; Cerebrovascular Circulation; Drug Evaluation; Female; Headache; Humans; Hypertension; M | 1989 |
Headache in stabilized giant cell arteritis: role of nifedipine.
Topics: Aged; Female; Giant Cell Arteritis; Headache; Humans; Nifedipine | 1988 |
Nifedipine--a survey of adverse effects. Four years' reporting in Sweden.
Topics: Adult; Aged; Angina Pectoris; Confusion; Erythema; Female; Headache; Heart Failure; Humans; Male; Mi | 1986 |
Nifedipine therapy for diffuse esophageal spasm.
Topics: Dizziness; Drug Evaluation; Esophageal Diseases; Female; Headache; Humans; Male; Manometry; Nifedipi | 1986 |