Page last updated: 2024-11-01

nifedipine and Glaucoma

nifedipine has been researched along with Glaucoma in 11 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)

Research Excerpts

ExcerptRelevanceReference
"To investigate ocular hemodynamic and visual function changes in patients with normal-tension glaucoma after treatment with a calcium channel blocker (nifedipine)."7.69Hemodynamic and visual function effects of oral nifedipine in patients with normal-tension glaucoma. ( Cantor, LB; Evans, DW; Harris, A; Martin, B, 1997)
"The results of a case-control study of 300 cataract patients and 609 controls indicate that long-term use of aspirin-like analgesics halves the risk of cataract."7.67Do aspirin-like analgesics protect against cataract? A case-control study. ( Harding, JJ; van Heyningen, R, 1986)
" The current investigations clarified the efficiency of this novel and unique NF loaded in situ gel for the control of the IOP compared to the conventional ophthalmic dosage forms."5.62Repurposing of nifedipine loaded in situ ophthalmic gel as a novel approach for glaucoma treatment. ( Ahmed, KA; El-Feky, YA; El-Telbany, DFA; El-Telbany, RFA; Fares, AR; Zayed, G, 2021)
"To study the effects of nilvadipine, a Ca2+ antagonist, on tissue circulation in the optic nerve head (ONH), choroid, and retina in rabbits and on the ONH circulation in normal tension glaucoma (NTG) patients."5.09Effects of nilvadipine, a calcium antagonist, on rabbit ocular circulation and optic nerve head circulation in NTG subjects. ( Araie, M; Nagahara, M; Sugiyama, T; Tamaki, Y; Tomita, K, 1999)
"To investigate ocular hemodynamic and visual function changes in patients with normal-tension glaucoma after treatment with a calcium channel blocker (nifedipine)."3.69Hemodynamic and visual function effects of oral nifedipine in patients with normal-tension glaucoma. ( Cantor, LB; Evans, DW; Harris, A; Martin, B, 1997)
"The results of a case-control study of 300 cataract patients and 609 controls indicate that long-term use of aspirin-like analgesics halves the risk of cataract."3.67Do aspirin-like analgesics protect against cataract? A case-control study. ( Harding, JJ; van Heyningen, R, 1986)
" The current investigations clarified the efficiency of this novel and unique NF loaded in situ gel for the control of the IOP compared to the conventional ophthalmic dosage forms."1.62Repurposing of nifedipine loaded in situ ophthalmic gel as a novel approach for glaucoma treatment. ( Ahmed, KA; El-Feky, YA; El-Telbany, DFA; El-Telbany, RFA; Fares, AR; Zayed, G, 2021)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's5 (45.45)18.2507
2000's0 (0.00)29.6817
2010's1 (9.09)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
El-Feky, YA1
Fares, AR1
Zayed, G1
El-Telbany, RFA1
Ahmed, KA1
El-Telbany, DFA1
Mayama, C1
Ishii, K1
Ota, T1
Tomidokoro, A1
Araie, M2
Vesti, E1
Harris, A1
Evans, DW1
Cantor, LB1
Martin, B1
Tomita, K1
Tamaki, Y1
Nagahara, M1
Sugiyama, T1
PrĂ¼nte-Glowazki, A1
Flammer, J2
Gasser, P1
Guthauser, U1
Mahler, F1
Kitazawa, Y2
Shirai, H2
Go, FJ2
van Heyningen, R1
Harding, JJ1
Asano, K1
Schnell, D1

Reviews

1 review available for nifedipine and Glaucoma

ArticleYear
[The diagnosis and treatment of glaucoma].
    Duodecim; laaketieteellinen aikakauskirja, 1995, Volume: 111, Issue:11

    Topics: Antihypertensive Agents; Glaucoma; Glaucoma, Open-Angle; Humans; Nifedipine

1995

Trials

1 trial available for nifedipine and Glaucoma

ArticleYear
Effects of nilvadipine, a calcium antagonist, on rabbit ocular circulation and optic nerve head circulation in NTG subjects.
    Investigative ophthalmology & visual science, 1999, Volume: 40, Issue:6

    Topics: Adult; Aged; Animals; Blood Flow Velocity; Calcium Channel Blockers; Double-Blind Method; Eye; Femal

1999

Other Studies

9 other studies available for nifedipine and Glaucoma

ArticleYear
Repurposing of nifedipine loaded in situ ophthalmic gel as a novel approach for glaucoma treatment.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 142

    Topics: Administration, Ophthalmic; Animals; Calcium Channel Blockers; Chemistry, Pharmaceutical; Delayed-Ac

2021
Changes in optic nerve head circulation in response to vasoactive agents: intereye comparison in monkeys with experimental unilateral glaucoma.
    Investigative ophthalmology & visual science, 2012, Aug-22, Volume: 53, Issue:9

    Topics: Animals; Arginine; Blood Circulation; Blood Flow Velocity; Calcium Channel Blockers; Disease Models,

2012
Hemodynamic and visual function effects of oral nifedipine in patients with normal-tension glaucoma.
    American journal of ophthalmology, 1997, Volume: 124, Issue:3

    Topics: Administration, Oral; Calcium Channel Blockers; Ciliary Arteries; Contrast Sensitivity; Eye; Female;

1997
[Ocular vasospasm. 4: Clinical examples].
    Klinische Monatsblatter fur Augenheilkunde, 1991, Volume: 198, Issue:5

    Topics: Adult; Arousal; Capillaries; Cold Temperature; Eye; Female; Glaucoma; Humans; Ischemia; Male; Middle

1991
Do vasospasms provoke ocular diseases?
    Angiology, 1990, Volume: 41, Issue:3

    Topics: Adolescent; Adult; Aged; Blood Flow Velocity; Capillaries; Cold Temperature; Fingers; Glaucoma; Huma

1990
The effect of Ca2(+) -antagonist on visual field in low-tension glaucoma.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1989, Volume: 227, Issue:5

    Topics: Administration, Oral; Blood Pressure; Cold Temperature; Female; Follow-Up Studies; Glaucoma; Heart R

1989
Do aspirin-like analgesics protect against cataract? A case-control study.
    Lancet (London, England), 1986, May-17, Volume: 1, Issue:8490

    Topics: Acetaminophen; Aged; Analgesics; Aspirin; Cataract; Diabetes Complications; Epidemiologic Methods; F

1986
[The effects of Ca2+-antagonist on visual field in low tension glaucoma].
    Nippon Ganka Gakkai zasshi, 1988, Volume: 92, Issue:5

    Topics: Administration, Oral; Adult; Aged; Blood Pressure; Female; Glaucoma; Humans; Intraocular Pressure; M

1988
[Behavior of intraocular pressure in healthy subjects and glaucoma patients following a single-dose and constant therapy with coronary agent, Bay a 1040].
    Klinische Monatsblatter fur Augenheilkunde, 1974, Volume: 165, Issue:6

    Topics: Adult; Capsules; Coronary Circulation; Drug Evaluation; Glaucoma; Humans; Intraocular Pressure; Meth

1974