nifedipine has been researched along with Gingivitis in 22 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Gingivitis: Inflammation of gum tissue (GINGIVA) without loss of connective tissue.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to examine the composition of subgingival plaque of 140 periodontal lesions in 35 patients with cardiovascular disorders who were administered nifedipine and manifested nifedipine-induced gingival overgrowth (GO)." | 7.70 | Subgingival microflora associated with nifedipine-induced gingival overgrowth. ( Andronikaki, A; Kamma, JJ; Mitsis, F; Nakou, M, 1998) |
| "In order to clarify a possible pathophysiological role of medullasin, a neutrophil elastase-like proteinase, in nifedipine (NF)-induced gingival overgrowth, the distributions of medullasin-positive cells immunostained in specimens from patients with NF-induced gingival overgrowth and chronic marginal gingivitis were compared in three different biopsy areas." | 7.69 | Possible roles of medullasin in nifedipine-induced human gingival overgrowth. ( Aoki, Y; Kato, I; Kunimatsu, K; Ozaki, Y, 1996) |
| "The factors associated with cyclosporin A (CsA)- and nifedipine (Nif)-induced gingival overgrowth were investigated in 113 renal transplant recipients receiving CsA alone (Group 1) [n = 61], CsA and Nif (Group 2) [n = 28], or azathioprine (Aza) (Control Group) [n = 24]." | 7.69 | Cyclosporin- and nifedipine-induced gingival overgrowth in renal transplant patients: correlations with periodontal and pharmacological parameters, and HLA-antigens. ( Barbaro, A; Margiotta, V; Pizzo, G; Pizzo, I, 1996) |
| "The effect of nifedipine and interleukin-alpha (IL-1alpha) on the cell proliferation and DNA synthesis was studied in human gingival fibroblasts derived from 5 patients who developed gingival overgrowth (nifedipine responders) and 5 patients who did not develop gingival overgrowth (nifedipine non-responders) in response to nifedipine." | 3.73 | The effect of IL-1alpha and nifedipine on cell proliferation and DNA synthesis in cultured human gingival fibroblasts. ( Akimoto, Y; Fujii, A; Matsumoto, H; Sato, N, 2005) |
| "Patients taking nifedipine are at high risk for gingival enlargement, and gingivitis acts as a predisposing factor." | 3.71 | Prevalence and risk of gingival enlargement in patients treated with nifedipine. ( Berini, L; Brunet, L; Farré, M; Mendieta, C; Miranda, J; Roset, P, 2001) |
| "Severe gingival hyperplasia (GH) is one of the most frequent side-effects associated with the prescription of Cyclosporine-A (CsA)." | 3.71 | Cyclosporin A-induced gingival overgrowth is unrelated to allograft function in renal transplant recipients. ( Baboolal, K; Newcombe, RG; Subramanian, N; Thomas, DW, 2001) |
| "The purpose of this study was to examine the composition of subgingival plaque of 140 periodontal lesions in 35 patients with cardiovascular disorders who were administered nifedipine and manifested nifedipine-induced gingival overgrowth (GO)." | 3.70 | Subgingival microflora associated with nifedipine-induced gingival overgrowth. ( Andronikaki, A; Kamma, JJ; Mitsis, F; Nakou, M, 1998) |
| "Drug-induced gingival overgrowth (DGO) is one of the well-recognized side effects of cyclosporin A (CsA) or nifedipine (Ni)." | 3.70 | Effectiveness of periodontal therapy in patients with drug-induced gingival overgrowth. Long-term results. ( Atilla, G; Baylas, H; Ilgenli, T, 1999) |
| " Gingival overgrowth was present in 41% of liver recipients receiving cyclosporin with or without nifedipine, but not in the majority receiving tacrolimus at the final examination." | 3.70 | Oral health in children undergoing liver transplantation. ( Beighton, D; O'Brien, G; Roberts, GJ; Sheehy, EC, 2000) |
| "In order to clarify a possible pathophysiological role of medullasin, a neutrophil elastase-like proteinase, in nifedipine (NF)-induced gingival overgrowth, the distributions of medullasin-positive cells immunostained in specimens from patients with NF-induced gingival overgrowth and chronic marginal gingivitis were compared in three different biopsy areas." | 3.69 | Possible roles of medullasin in nifedipine-induced human gingival overgrowth. ( Aoki, Y; Kato, I; Kunimatsu, K; Ozaki, Y, 1996) |
| "The factors associated with cyclosporin A (CsA)- and nifedipine (Nif)-induced gingival overgrowth were investigated in 113 renal transplant recipients receiving CsA alone (Group 1) [n = 61], CsA and Nif (Group 2) [n = 28], or azathioprine (Aza) (Control Group) [n = 24]." | 3.69 | Cyclosporin- and nifedipine-induced gingival overgrowth in renal transplant patients: correlations with periodontal and pharmacological parameters, and HLA-antigens. ( Barbaro, A; Margiotta, V; Pizzo, G; Pizzo, I, 1996) |
| "Gingival overgrowth was noticed in 29% of the patients." | 1.30 | The clinical effects of nifedipine on periodontal status. ( Caglayan, F; Caglayan, G; Eratalay, K; Tavassoli, S; Yamalik, N, 1998) |
| "The nifedipine-treated rats (experimental group) were fed a caries-inducing diet containing nifedipine either with or without infection, while the nifedipine-untreated rats (control group) were fed the same diet, similarly with or without the infection." | 1.29 | Nifedipine-induced gingival overgrowth in the presence or absence of gingival inflammation in rats. ( Ishida, H; Kato, K; Loyola-Rodriguez, JP; Morisaki, I; Nagata, T, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (59.09) | 18.2507 |
| 2000's | 8 (36.36) | 29.6817 |
| 2010's | 1 (4.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bencivenni, D | 1 |
| Neiders, ME | 1 |
| Andreana, S | 1 |
| Moffitt, ML | 1 |
| Cohen, RE | 1 |
| Sato, N | 1 |
| Matsumoto, H | 1 |
| Akimoto, Y | 1 |
| Fujii, A | 1 |
| Kantarci, A | 1 |
| Augustin, P | 1 |
| Firatli, E | 1 |
| Sheff, MC | 1 |
| Hasturk, H | 1 |
| Graves, DT | 1 |
| Trackman, PC | 1 |
| Kanno, CM | 1 |
| Oliveira, JA | 1 |
| Garcia, JF | 1 |
| Castro, AL | 1 |
| Crivelini, MM | 1 |
| Ellis, JS | 2 |
| Seymour, RA | 2 |
| Thomason, JM | 2 |
| Butler, TJ | 2 |
| Idle, JR | 1 |
| Morisaki, I | 2 |
| Kato, K | 1 |
| Loyola-Rodriguez, JP | 1 |
| Nagata, T | 2 |
| Ishida, H | 2 |
| Romanos, GE | 2 |
| Strub, JR | 1 |
| Bernimoulin, JP | 2 |
| Nishikawa, S | 1 |
| Oka, T | 1 |
| Kunimatsu, K | 1 |
| Ozaki, Y | 1 |
| Aoki, Y | 1 |
| Kato, I | 1 |
| Margiotta, V | 1 |
| Pizzo, I | 1 |
| Pizzo, G | 1 |
| Barbaro, A | 1 |
| Tavassoli, S | 1 |
| Yamalik, N | 1 |
| Caglayan, F | 1 |
| Caglayan, G | 1 |
| Eratalay, K | 1 |
| Nakou, M | 1 |
| Kamma, JJ | 1 |
| Andronikaki, A | 1 |
| Mitsis, F | 1 |
| Varga, E | 1 |
| Mair, LH | 1 |
| Steele, JG | 1 |
| Robertson, P | 1 |
| Ilgenli, T | 1 |
| Atilla, G | 1 |
| Baylas, H | 1 |
| Sheehy, EC | 1 |
| Roberts, GJ | 1 |
| Beighton, D | 1 |
| O'Brien, G | 1 |
| Houston, GD | 1 |
| Miranda, J | 1 |
| Brunet, L | 1 |
| Roset, P | 1 |
| Berini, L | 1 |
| Farré, M | 1 |
| Mendieta, C | 1 |
| Thomas, DW | 1 |
| Baboolal, K | 1 |
| Subramanian, N | 1 |
| Newcombe, RG | 1 |
| Bullón, P | 1 |
| Machuca, G | 1 |
| Armas, JR | 1 |
| Rojas, JL | 1 |
| Jiménez, G | 1 |
| Schröter-Kermani, C | 1 |
| Hinz, N | 1 |
| Sooriyamoorthy, M | 1 |
| Gower, DB | 1 |
| Eley, BM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of the Effects of PRF, CGF and AFG Application on Wound Healing Following Gingivectomy and Gingivoplasty Operations: a Randomized Controlled Clinical Trial[NCT04805463] | 19 participants (Actual) | Interventional | 2020-01-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for nifedipine and Gingivitis
| Article | Year |
|---|---|
Pathogenesis of drug-induced gingival overgrowth. A review of studies in the rat model.
Topics: Age Factors; Animals; Anticonvulsants; Calcium Channel Blockers; Cyclosporine; Dental Plaque; Diseas | 1996 |
21 other studies available for nifedipine and Gingivitis
| Article | Year |
|---|---|
Effect of local nifedipine administration on rat gingiva.
Topics: Animals; Calcium Channel Blockers; Cell Count; Connective Tissue; Dose-Response Relationship, Drug; | 2012 |
The effect of IL-1alpha and nifedipine on cell proliferation and DNA synthesis in cultured human gingival fibroblasts.
Topics: Aged; Calcium Channel Blockers; Case-Control Studies; Cell Proliferation; Cells, Cultured; DNA; DNA | 2005 |
Apoptosis in gingival overgrowth tissues.
Topics: Anticonvulsants; Apoptosis; Calcium Channel Blockers; Case-Control Studies; Caspase 3; Cell Prolifer | 2007 |
Effects of cyclosporin, phenytoin, and nifedipine on the synthesis and degradation of gingival collagen in tufted capuchin monkeys (Cebus apella): histochemical and MMP-1 and -2 and collagen I gene expression analyses.
Topics: Animals; Anticonvulsants; Azo Compounds; Biopsy; Calcium Channel Blockers; Cebus; Collagen; Collagen | 2008 |
Periodontal variables affecting nifedipine sequestration in gingival crevicular fluid.
Topics: Adult; Calcium Channel Blockers; Confounding Factors, Epidemiologic; Dental Plaque Index; Dose-Respo | 1995 |
Nifedipine-induced gingival overgrowth in the presence or absence of gingival inflammation in rats.
Topics: Analysis of Variance; Animals; Dental Plaque; Dental Plaque Index; Disease Models, Animal; Gingival | 1993 |
Immunohistochemical distribution of extracellular matrix proteins as a diagnostic parameter in healthy and diseased gingiva.
Topics: Adult; Aged; Collagen; Cyclosporine; Extracellular Matrix Proteins; Female; Fibronectins; Fluorescen | 1993 |
Possible roles of medullasin in nifedipine-induced human gingival overgrowth.
Topics: Adult; Antihypertensive Agents; Calcium Channel Blockers; Chronic Disease; Coloring Agents; Connecti | 1996 |
Cyclosporin- and nifedipine-induced gingival overgrowth in renal transplant patients: correlations with periodontal and pharmacological parameters, and HLA-antigens.
Topics: Adolescent; Adult; Azathioprine; Calcium Channel Blockers; Child; Cyclosporine; Dental Calculus; Den | 1996 |
The clinical effects of nifedipine on periodontal status.
Topics: Adult; Age Factors; Aged; Analysis of Variance; Angina Pectoris; Calcium Channel Blockers; Dental Pl | 1998 |
Subgingival microflora associated with nifedipine-induced gingival overgrowth.
Topics: Adult; Age Factors; Aged; Bacteroidaceae; Bacteroides; Calcium Channel Blockers; Campylobacter; Capn | 1998 |
Medication influencing the development of gingival overgrowth in renal transplant patients.
Topics: Cyclosporine; Gingiva; Gingival Hyperplasia; Gingivitis; Humans; Immunosuppressive Agents; Kidney Fa | 1998 |
Prevalence of gingival overgrowth induced by calcium channel blockers: a community-based study.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Analysis of Variance; Calcium Channel Blockers; Dental P | 1999 |
Effectiveness of periodontal therapy in patients with drug-induced gingival overgrowth. Long-term results.
Topics: Adult; Age Factors; Calcium Channel Blockers; Cyclosporine; Dental Plaque Index; Dental Prophylaxis; | 1999 |
Oral health in children undergoing liver transplantation.
Topics: Adolescent; Case-Control Studies; Chi-Square Distribution; Child; Child, Preschool; Cyclosporine; De | 2000 |
Oral pathology case of the quarter.
Topics: Angina Pectoris; Calcium Channel Blockers; Diagnosis, Differential; Gingival Hyperplasia; Gingivitis | 2001 |
Prevalence and risk of gingival enlargement in patients treated with nifedipine.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Calcium Channel Blockers; Cross-Se | 2001 |
Cyclosporin A-induced gingival overgrowth is unrelated to allograft function in renal transplant recipients.
Topics: Adolescent; Adult; Aged; Azathioprine; Calcium Channel Blockers; Child; Child, Preschool; Creatinine | 2001 |
The gingival inflammatory infiltrate in cardiac patients treated with calcium antagonists.
Topics: Analysis of Variance; Calcium Channel Blockers; Case-Control Studies; Chi-Square Distribution; Dilti | 2001 |
Distribution of fibronectin in healthy, inflamed and drug-induced gingival hyperplasia.
Topics: Actin Cytoskeleton; Adult; Connective Tissue; Connective Tissue Cells; Cyclosporine; Dental Plaque; | 1992 |
Androgen metabolism in gingival hyperplasia induced by nifedipine and cyclosporin.
Topics: Adult; Androstenedione; Cyclosporins; Dihydrotestosterone; Female; Gingival Hypertrophy; Gingivitis; | 1990 |