Page last updated: 2024-11-01

nifedipine and Gingival Pocket

nifedipine has been researched along with Gingival Pocket in 7 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Gingival Pocket: An abnormal extension of a gingival sulcus not accompanied by the apical migration of the epithelial attachment.

Research Excerpts

ExcerptRelevanceReference
"Patients with nifedipine-induced gingival hyperplasia (GH) often require continued calcium channel blocker therapy."9.08Regression of nifedipine-induced gingival hyperplasia following switch to a same class calcium channel blocker, isradipine. ( Bednarczyk, EM; Bissada, NF; Carlson, M; Sheehan, H; Westbrook, P, 1997)
"The purpose of this study was to examine the composition of subgingival plaque of 140 periodontal lesions in 35 patients with cardiovascular disorders who were administered nifedipine and manifested nifedipine-induced gingival overgrowth (GO)."7.70Subgingival microflora associated with nifedipine-induced gingival overgrowth. ( Andronikaki, A; Kamma, JJ; Mitsis, F; Nakou, M, 1998)
"In order to clarify a possible pathophysiological role of medullasin, a neutrophil elastase-like proteinase, in nifedipine (NF)-induced gingival overgrowth, the distributions of medullasin-positive cells immunostained in specimens from patients with NF-induced gingival overgrowth and chronic marginal gingivitis were compared in three different biopsy areas."7.69Possible roles of medullasin in nifedipine-induced human gingival overgrowth. ( Aoki, Y; Kato, I; Kunimatsu, K; Ozaki, Y, 1996)
"Treatment with either cyclosporin A or nifedipine may induce gingival hyperplasia."7.69Gingival hyperplasia: interaction between cyclosporin A and nifedipine? A case report. ( Babich, S; Jackson, C, 1997)
"Patients with nifedipine-induced gingival hyperplasia (GH) often require continued calcium channel blocker therapy."5.08Regression of nifedipine-induced gingival hyperplasia following switch to a same class calcium channel blocker, isradipine. ( Bednarczyk, EM; Bissada, NF; Carlson, M; Sheehan, H; Westbrook, P, 1997)
"Patients taking nifedipine are at high risk for gingival enlargement, and gingivitis acts as a predisposing factor."3.71Prevalence and risk of gingival enlargement in patients treated with nifedipine. ( Berini, L; Brunet, L; Farré, M; Mendieta, C; Miranda, J; Roset, P, 2001)
"The purpose of this study was to examine the composition of subgingival plaque of 140 periodontal lesions in 35 patients with cardiovascular disorders who were administered nifedipine and manifested nifedipine-induced gingival overgrowth (GO)."3.70Subgingival microflora associated with nifedipine-induced gingival overgrowth. ( Andronikaki, A; Kamma, JJ; Mitsis, F; Nakou, M, 1998)
"In order to clarify a possible pathophysiological role of medullasin, a neutrophil elastase-like proteinase, in nifedipine (NF)-induced gingival overgrowth, the distributions of medullasin-positive cells immunostained in specimens from patients with NF-induced gingival overgrowth and chronic marginal gingivitis were compared in three different biopsy areas."3.69Possible roles of medullasin in nifedipine-induced human gingival overgrowth. ( Aoki, Y; Kato, I; Kunimatsu, K; Ozaki, Y, 1996)
"Treatment with either cyclosporin A or nifedipine may induce gingival hyperplasia."3.69Gingival hyperplasia: interaction between cyclosporin A and nifedipine? A case report. ( Babich, S; Jackson, C, 1997)
" Gingival changes in the nifedipine patients were not related to drug dosage or plaque scores."1.28The incidence and severity of nifedipine-induced gingival overgrowth. ( Barclay, S; Idle, JR; Seymour, RA; Thomason, JM, 1992)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (85.71)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kunimatsu, K1
Ozaki, Y1
Aoki, Y1
Kato, I1
Jackson, C1
Babich, S1
Westbrook, P1
Bednarczyk, EM1
Carlson, M1
Sheehan, H1
Bissada, NF1
Nakou, M1
Kamma, JJ1
Andronikaki, A1
Mitsis, F1
Miranda, J1
Brunet, L1
Roset, P1
Berini, L1
Farré, M1
Mendieta, C1
Romanos, GE1
Schröter-Kermani, C1
Hinz, N1
Bernimoulin, JP1
Barclay, S1
Thomason, JM1
Idle, JR1
Seymour, RA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of the Effects of PRF, CGF and AFG Application on Wound Healing Following Gingivectomy and Gingivoplasty Operations: a Randomized Controlled Clinical Trial[NCT04805463]19 participants (Actual)Interventional2020-01-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for nifedipine and Gingival Pocket

ArticleYear
Regression of nifedipine-induced gingival hyperplasia following switch to a same class calcium channel blocker, isradipine.
    Journal of periodontology, 1997, Volume: 68, Issue:7

    Topics: Adult; Aged; Antihypertensive Agents; Biopsy; Calcium Channel Blockers; Dental Plaque Index; Evaluat

1997

Other Studies

6 other studies available for nifedipine and Gingival Pocket

ArticleYear
Possible roles of medullasin in nifedipine-induced human gingival overgrowth.
    Archives of oral biology, 1996, Volume: 41, Issue:1

    Topics: Adult; Antihypertensive Agents; Calcium Channel Blockers; Chronic Disease; Coloring Agents; Connecti

1996
Gingival hyperplasia: interaction between cyclosporin A and nifedipine? A case report.
    The New York state dental journal, 1997, Volume: 63, Issue:1

    Topics: Calcium Channel Blockers; Cyclosporine; Drug Synergism; Female; Gingival Hyperplasia; Gingival Pocke

1997
Subgingival microflora associated with nifedipine-induced gingival overgrowth.
    Journal of periodontology, 1998, Volume: 69, Issue:6

    Topics: Adult; Age Factors; Aged; Bacteroidaceae; Bacteroides; Calcium Channel Blockers; Campylobacter; Capn

1998
Prevalence and risk of gingival enlargement in patients treated with nifedipine.
    Journal of periodontology, 2001, Volume: 72, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Calcium Channel Blockers; Cross-Se

2001
Distribution of fibronectin in healthy, inflamed and drug-induced gingival hyperplasia.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1992, Volume: 21, Issue:6

    Topics: Actin Cytoskeleton; Adult; Connective Tissue; Connective Tissue Cells; Cyclosporine; Dental Plaque;

1992
The incidence and severity of nifedipine-induced gingival overgrowth.
    Journal of clinical periodontology, 1992, Volume: 19, Issue:5

    Topics: Atenolol; Dental Plaque Index; Female; Gingival Hyperplasia; Gingival Pocket; Humans; Incidence; Mal

1992