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nifedipine and Gingival Hypertrophy

nifedipine has been researched along with Gingival Hypertrophy in 13 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Gingival Hypertrophy: Abnormal enlargement or overgrowth of the gingivae brought about by enlargement of existing cells.

Research Excerpts

ExcerptRelevanceReference
"Nifedipine-induced gingival hypertrophy is a rare side effect reported by the producers of this drug but, surely, not well known in all its aspects."7.68[Nifedipine and gingival hypertrophy]. ( Borgia, MC; Calpicchio, A; De Paola, G; Di Folco, G, 1991)
"Gingival hypertrophy was observed in 52 subjects (63."5.30[Gingival hypertrophy due to cyclosporine. A clinico-statistical study in 82 patients]. ( Gennari, PU; Macaluso, GM; Savi, A; Vescovi, P, 1997)
"A case of severe gingival overgrowth associated with combined drug therapy of cyclosporin A and nifedipine is reported."3.69Combined treatment approach to gingival overgrowth due to drug therapy. ( Darbar, UR; Hopper, C; Newman, HN; Speight, PM, 1996)
" Gingival overgrowth associated with cyclosporin (immunosuppressant agent) and nifedipine (calcium channel blocker) is well documented."3.69Periodontal management of gingival overgrowth in the heart transplant patient: a case report. ( Khocht, A; Schneider, LC, 1997)
"Nifedipine-induced gingival hypertrophy is a rare side effect reported by the producers of this drug but, surely, not well known in all its aspects."3.68[Nifedipine and gingival hypertrophy]. ( Borgia, MC; Calpicchio, A; De Paola, G; Di Folco, G, 1991)
"Gingival hypertrophy was observed in 52 subjects (63."1.30[Gingival hypertrophy due to cyclosporine. A clinico-statistical study in 82 patients]. ( Gennari, PU; Macaluso, GM; Savi, A; Vescovi, P, 1997)
"The nifedipine-treated rats (experimental group) were fed a caries-inducing diet containing nifedipine either with or without infection, while the nifedipine-untreated rats (control group) were fed the same diet, similarly with or without the infection."1.29Nifedipine-induced gingival overgrowth in the presence or absence of gingival inflammation in rats. ( Ishida, H; Kato, K; Loyola-Rodriguez, JP; Morisaki, I; Nagata, T, 1993)
"Nifedipine was detected in the gingival crevicular fluid of seven subjects (all responders, and two non-responders)."1.29Disposition of nifedipine in plasma and gingival crevicular fluid in relation to drug-induced gingival overgrowth. ( Ellis, JS; Idle, JR; Monkman, S; Seymour, RA, 1993)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19902 (15.38)18.7374
1990's9 (69.23)18.2507
2000's1 (7.69)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Matsumura, M1
Suzuki, Y1
Yamagishi, M1
Kawano, M1
Tipton, DA1
Fry, HR1
Dabbous, MK1
Morisaki, I1
Kato, K1
Loyola-Rodriguez, JP1
Nagata, T1
Ishida, H1
Ellis, JS1
Seymour, RA1
Monkman, S1
Idle, JR1
Darbar, UR1
Hopper, C1
Speight, PM1
Newman, HN1
Vescovi, P1
Savi, A1
Macaluso, GM1
Gennari, PU1
Khocht, A1
Schneider, LC1
Lowenthal, A1
Lowenthal, MN1
Pan, WL1
Chan, CP1
Huang, CC1
Lai, MK1
Borgia, MC1
De Paola, G1
Di Folco, G1
Calpicchio, A1
Sooriyamoorthy, M1
Gower, DB1
Eley, BM1
Matarasso, S1
Vaia, E1
Caputo, G1
Riccitiello, F1
Boisnic, S1
Frances, C1

Reviews

2 reviews available for nifedipine and Gingival Hypertrophy

ArticleYear
[Hyperthrophic-hyperplastic gingival diseases. Etiopathogenic, clinical assessment and diagnostic guide].
    Minerva stomatologica, 1989, Volume: 38, Issue:5

    Topics: Anticonvulsants; Cyclosporins; Fibromatosis, Gingival; Gingival Hyperplasia; Gingival Hypertrophy; G

1989
[Gingival hypertrophy].
    Annales de dermatologie et de venereologie, 1988, Volume: 115, Issue:3

    Topics: Ascorbic Acid Deficiency; Cyclosporins; Female; Gingival Hypertrophy; Gingival Neoplasms; Hamartoma

1988

Other Studies

11 other studies available for nifedipine and Gingival Hypertrophy

ArticleYear
Nifedipine-induced gingival hypertrophy.
    Internal medicine (Tokyo, Japan), 2012, Volume: 51, Issue:1

    Topics: Calcium Channel Blockers; Gingival Hypertrophy; Humans; Male; Middle Aged; Nifedipine

2012
Altered collagen metabolism in nifedipine-induced gingival overgrowth.
    Journal of periodontal research, 1994, Volume: 29, Issue:6

    Topics: Cells, Cultured; Collagen; Enzyme-Linked Immunosorbent Assay; Female; Fibroblasts; Fibronectins; Gin

1994
Nifedipine-induced gingival overgrowth in the presence or absence of gingival inflammation in rats.
    Journal of periodontal research, 1993, Volume: 28, Issue:6 Pt 1

    Topics: Analysis of Variance; Animals; Dental Plaque; Dental Plaque Index; Disease Models, Animal; Gingival

1993
Disposition of nifedipine in plasma and gingival crevicular fluid in relation to drug-induced gingival overgrowth.
    Journal of periodontal research, 1993, Volume: 28, Issue:5

    Topics: Adult; Aged; Chi-Square Distribution; Gingival Crevicular Fluid; Gingival Hypertrophy; Humans; Male;

1993
Combined treatment approach to gingival overgrowth due to drug therapy.
    Journal of clinical periodontology, 1996, Volume: 23, Issue:10

    Topics: Blood Loss, Surgical; Calcium Channel Blockers; Carbon Dioxide; Cyclosporine; Gingival Hemorrhage; G

1996
[Gingival hypertrophy due to cyclosporine. A clinico-statistical study in 82 patients].
    Minerva stomatologica, 1997, Volume: 46, Issue:4

    Topics: Adolescent; Adult; Calcium Channel Blockers; Cyclosporine; DMF Index; Drug Therapy, Combination; Fem

1997
Periodontal management of gingival overgrowth in the heart transplant patient: a case report.
    Journal of periodontology, 1997, Volume: 68, Issue:11

    Topics: Calcium Channel Blockers; Candidiasis, Oral; Connective Tissue; Cyclosporine; Epithelium; Fibrosis;

1997
Gingival hypertrophy due to drugs.
    The Israel Medical Association journal : IMAJ, 2001, Volume: 3, Issue:9

    Topics: Adolescent; Anticonvulsants; Female; Gingival Hypertrophy; Humans; Male; Middle Aged; Nifedipine; Ph

2001
Cyclosporine-induced gingival overgrowth.
    Transplantation proceedings, 1992, Volume: 24, Issue:4

    Topics: Cyclosporine; Dental Plaque; Gingival Hypertrophy; Humans; Immunosuppressive Agents; Kidney Transpla

1992
[Nifedipine and gingival hypertrophy].
    Cardiologia (Rome, Italy), 1991, Volume: 36, Issue:7

    Topics: Angina Pectoris; Drug Therapy, Combination; Gingival Hypertrophy; Humans; Male; Middle Aged; Nifedip

1991
Androgen metabolism in gingival hyperplasia induced by nifedipine and cyclosporin.
    Journal of periodontal research, 1990, Volume: 25, Issue:1

    Topics: Adult; Androstenedione; Cyclosporins; Dihydrotestosterone; Female; Gingival Hypertrophy; Gingivitis;

1990