Page last updated: 2024-11-01

nifedipine and Gingival Hyperplasia

nifedipine has been researched along with Gingival Hyperplasia in 145 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Gingival Hyperplasia: Non-inflammatory enlargement of the gingivae produced by factors other than local irritation. It is characteristically due to an increase in the number of cells. (From Jablonski's Dictionary of Dentistry, 1992, p400)

Research Excerpts

ExcerptRelevanceReference
"Patients with nifedipine-induced gingival hyperplasia (GH) often require continued calcium channel blocker therapy."9.08Regression of nifedipine-induced gingival hyperplasia following switch to a same class calcium channel blocker, isradipine. ( Bednarczyk, EM; Bissada, NF; Carlson, M; Sheehan, H; Westbrook, P, 1997)
"Thirteen psoriatic patients with hypertension during the course of cyclosporin A therapy were treated for 25 months with a calcium channel blocker, sustained-release nifedipine, to study the clinical antihypertensive effects and adverse events during treatment with both drugs."9.08Long-term efficacy and adverse event of nifedipine sustained-release tablets for cyclosporin A-induced hypertension in patients with psoriasis. ( Furue, M; Koga, T; Nakayama, J, 1998)
"Nifedipine increases the frequency and severity of gingival hyperplasia associated with CyA therapy in renal transplant recipients and this effect appears to be independent of whole-blood CyA levels."9.07Cyclosporin, nifedipine and gingival hyperplasia: a randomized controlled study. ( Donnelly, PK; Edwards, CM; Morgan, JD; Swarbrick, MJ, 1994)
"A comprehensive review of the literature and analysis of the clinical history, mechanisms, pathogenesis, histology, and management of nifedipine-induced gingival hyperplasia is reported."8.79Nifedipine-induced gingival hyperplasia. A comprehensive review and analysis. ( Eckler, M; Gornitsky, M; Harel-Raviv, M; Lalani, K; Raviv, E, 1995)
"Nifedipine-induced gingival hyperplasia is a newly reported but relatively unknown side effect."8.77Nifedipine-induced gingival hyperplasia: case reports and literature review. ( Gotsman, M; Nyska, A; Nyska, M; Sela, M; Zlotogorski, A, 1989)
" Among the calcium channel blockers, nifedipine has been shown to be most frequently associated with drug-induced gingival hyperplasia."8.12Amlodipine Induced Gum Hypertrophy: A Rare Case Report. ( Bohra, GK; Chhabra, V; Kumar, D; Midha, N; Reddy, SC, 2022)
"This first case report of gingival hyperplasia induced by nifedipine in pregnancy could be used as a reference for clinicians in the management of this adverse effect during the pregnancy."7.85Nifedipine Induced Gingival Hyperplasia in Pregnancy: A Case Report. ( Brochet, MS; Harry, M; Morin, F, 2017)
"The use of calcium channel blockers, especially nifedipine, causes gingival hyperplasia which leads to the destruction of the deeper periodontal tissues."7.74[Histometric analysis of gingival hyperplasia in Wistar rats during nifedipine administration]. ( Brkić, Z, 2007)
"The results of our present study indicate that the synergistic overexpression of c-Myc and bcl-2 oncoprotein may be related to the pathogenesis of gingival hyperplasia induced by nifedipine and phenytoin, especially to the morphogenesis of hyperplastic epithelia."7.70Immunolocalizaiton of c-Myc and bcl-2 proto-oncogene products in gingival hyperplasia induced by nifedipine and phenytoin. ( Mori, S; Saito, K; Sakamoto, S; Tanda, N, 2000)
"Although it has been thought that drug-induced gingival hyperplasia is not related to tumorigenesis, recent case reports have shown that squamous cell carcinomas may arise in gingival hyperplasia induced by cyclosporin and phenytoin."7.70Expression of p53 protein and Ki-67 antigen in gingival hyperplasia induced by nifedipine and phenytoin. ( Mori, S; Saito, K; Sakamoto, S; Tanda, N, 1999)
"This study investigated the prevalence of gingival hyperplasia in subjects who were undergoing treatment with a calcium channel blocker, nifedipine, in dentate and edentulous subjects."7.69Prevalence of nifedipine-induced gingival hyperplasia. ( Edson, RG; Lee, KK; Nery, EB; Pruthi, VK; Watson, J, 1995)
" Nifedipine is often used to control hypertension in kidney graft recipients."7.69Nifedipine aggravates cyclosporine A-induced gingival hyperplasia. ( Albers, N; Beier, C; Bohnhorst, B; Bökenkamp, A; Brodehl, J; Offner, G, 1994)
"Gingival hyperplasia caused by the use of nifedipine has been extensively reported."7.69Clinical assessment of gingival hyperplasia in patients treated with nifedipine. ( Bullon, P; Lacalle, JR; Machuca, G; Martinez-Sahuquillo, A; Rios, JV; Rojas, J, 1994)
"Treatment with either cyclosporin A or nifedipine may induce gingival hyperplasia."7.69Gingival hyperplasia: interaction between cyclosporin A and nifedipine? A case report. ( Babich, S; Jackson, C, 1997)
"Two cases of gingival hyperplasia associated with long-term administration of nifedipine, a drug that dilates coronary arteries, are reported."7.68Nifedipine-induced gingival hyperplasia: a clinical and in vitro study. ( Hamasaki, A; Ishida, H; Kasahara, S; Kido, J; Nagata, T; Nishikawa, S; Tada, H; Wakano, Y, 1991)
"We describe 4 cases of gingival hyperplasia induced by nifedipine, together with clinical and histological findings."7.68Gingival hyperplasia induced by nifedipine. ( Akimoto, Y; Fujii, A; Kaneko, K; Kawana, T; Nakano, Y; Nakao, S; Omata, H; Shibutani, J; Tanaka, S; Teshigawara, H, 1991)
"Gingival hyperplasia is an adverse reaction of nifedipine therapy."7.68Nifedipine-induced gingival hyperplasia. ( Barak, S; Ben Yehuda, A; Katz, J; Rotstein, I, 1992)
"This article has summarized observations and results of controlled laboratory and clinical studies of drug-induced gingival hyperplasia associated with phenytoin, cyclosporine, and nifedipine use."7.67Drug-induced gingival hyperplasia: phenytoin, cyclosporine, and nifedipine. ( Butler, RT; Kaldahl, WB; Kalkwarf, KL, 1987)
"Nifedipine-induced gingival hyperplasia was first reported in 1984."7.67Nifedipine-induced gingival hyperplasia. ( Yusof, WZ, 1989)
"In a 32-year-old patient a relationship was suggested between the development of gingival hyperplasia and the vasodilating drug nifedipine (Adalat)."7.67Gingival hyperplasia induced by nifedipine, an arterial vasodilating drug. ( Hes, J; Tuinzing, DB; van der Wall, EE, 1985)
"A case of gingival hyperplasia associated with the administration of nifedipine is reported."7.67Gingival hyperplasia associated with nifedipine therapy. Report of a case. ( Freedman, PD; Lederman, D; Lumerman, H; Reuben, S, 1984)
"We observed marked gingival hyperplasia, similar clinically and histologically to the hyperplasia caused by 5:5 sodium diphenylhydantoin (Dilantin) during the last 18 months in five patients treated by nifedipine."7.67Gingival hyperplasia caused by nifedipine--a preliminary report. ( Behar, S; Engelberg, IS; Kishon, Y; Ramon, Y, 1984)
"Two cases of gingival hyperplasia associated with the administration of nifedipine are presented in this paper."7.67[Gingival hyperplasia induced by nifedipine. Report of two cases]. ( Andronikaki-Faldami, A; Nikolatou, O; Nikolopoulou-Papaconstantinou, A; Psaroulis, K, 1989)
"We describe a case of gingival hyperplasia in a 36-year-old renal transplantation recipient treated with nifedipine for severe arterial hypertension."7.67Gingival hyperplasia by nifedipine. Report of a case. ( Bencini, PL; Crosti, C; Menni, S; Montagnino, G; Piccinno, R; Sala, F; Tarantino, A, 1985)
"In a 66-year-old patient a relationship between the development of gingival hyperplasia and nifedipine treatment was suggested."7.67[Gingival hyperplasia caused by nifedipine]. ( Flaminio, R; Pivotti, F; Scardi, S, 1986)
"Gingival hyperplasia induced by nifedipine (Procardia), a calcium channel-blocking agent used as an anti-anginal drug, was studied."7.67Nifedipine-induced gingival hyperplasia. A histochemical and ultrastructural study. ( Howell, LP; Lucas, RM; Wall, BA, 1985)
"The prevalence of the nifedipine-induced gingival hyperplasia is ranging from 0."6.19[Clinical experience with the treatment of gingival hyperplasia induced by calcium channel blocking agents]. ( Benedek, E; Gera, I; Keglevich, T, 1999)
"Twenty-day nifedipine treatment induced gingival hyperplasia accompanied with reduced salivary flow rate and concentrations of total protein, epidermal growth factor (EGF) and calcium in comparison with controls."5.33On the relation of nitric oxide to nifedipine-induced gingival hyperplasia and impaired submandibular glands function in rats in vivo. ( Abdollahi, M; Khorasani, R; Minaiee, B; Rezaie, A; Rezaie, S, 2005)
"Nifedipine is a new agent belonging to the calcium antagonist group of drugs, applied clinically to circulatory disorders, such as essential hypertension, renal hypertension and angina cordis and has been rapid in gaining popularity in Japan."5.28[A case of gingival hyperplasia induced by nifedipine]. ( Kakami, K; Kaneko, M; Katayama, H; Kinoshita, Y; Suzuki, N; Takai, Y, 1990)
"Patients with nifedipine-induced gingival hyperplasia (GH) often require continued calcium channel blocker therapy."5.08Regression of nifedipine-induced gingival hyperplasia following switch to a same class calcium channel blocker, isradipine. ( Bednarczyk, EM; Bissada, NF; Carlson, M; Sheehan, H; Westbrook, P, 1997)
"Thirteen psoriatic patients with hypertension during the course of cyclosporin A therapy were treated for 25 months with a calcium channel blocker, sustained-release nifedipine, to study the clinical antihypertensive effects and adverse events during treatment with both drugs."5.08Long-term efficacy and adverse event of nifedipine sustained-release tablets for cyclosporin A-induced hypertension in patients with psoriasis. ( Furue, M; Koga, T; Nakayama, J, 1998)
"Nifedipine increases the frequency and severity of gingival hyperplasia associated with CyA therapy in renal transplant recipients and this effect appears to be independent of whole-blood CyA levels."5.07Cyclosporin, nifedipine and gingival hyperplasia: a randomized controlled study. ( Donnelly, PK; Edwards, CM; Morgan, JD; Swarbrick, MJ, 1994)
" Among the calcium channel blockers, nifedipine has been shown to be most frequently associated with drug-induced gingival hyperplasia."4.12Amlodipine Induced Gum Hypertrophy: A Rare Case Report. ( Bohra, GK; Chhabra, V; Kumar, D; Midha, N; Reddy, SC, 2022)
"Severe gingival hyperplasia (GH) is one of the most frequent side-effects associated with the prescription of Cyclosporine-A (CsA)."3.71Cyclosporin A-induced gingival overgrowth is unrelated to allograft function in renal transplant recipients. ( Baboolal, K; Newcombe, RG; Subramanian, N; Thomas, DW, 2001)
"Although it has been thought that drug-induced gingival hyperplasia is not related to tumorigenesis, recent case reports have shown that squamous cell carcinomas may arise in gingival hyperplasia induced by cyclosporin and phenytoin."3.70Expression of p53 protein and Ki-67 antigen in gingival hyperplasia induced by nifedipine and phenytoin. ( Mori, S; Saito, K; Sakamoto, S; Tanda, N, 1999)
"A case report is presented, which describes a kidney-transplant recipient medicated simultaneously with both cyclosporin A and nifedipine and who developed an extreme form of gingival hyperplasia."3.70[Drug-induced gingival hyperplasia]. ( Ferrari, P; Nohl, F, 1998)
" Although KGF has been implicated in a number of hyperplastic pathologies, it has not previously been investigated in gingival hyperplasia (GH), an adverse side-effect of three pharmacologically different types of drugs, including the anti-hypertensive drug nifedipine (NIF)."3.70Keratinocyte growth factor is upregulated by the hyperplasia-inducing drug nifedipine. ( Das, SJ; Olsen, I, 2000)
"Treatment with either cyclosporin A or nifedipine may induce gingival hyperplasia."3.69Gingival hyperplasia: interaction between cyclosporin A and nifedipine? A case report. ( Babich, S; Jackson, C, 1997)
"Gingival hyperplasia caused by the use of nifedipine has been extensively reported."3.69Clinical assessment of gingival hyperplasia in patients treated with nifedipine. ( Bullon, P; Lacalle, JR; Machuca, G; Martinez-Sahuquillo, A; Rios, JV; Rojas, J, 1994)
"Human gingival fibroblasts from six patients who developed gingival hyperplasia as a result of nifedipine medication and five who did not were studied for the effects of calcium-channel blockers (nifedipine, diltiazem, verapamil and nicardipine) on cell proliferation, DNA synthesis and collagen synthesis."3.69Effect of calcium-channel blockers on cell proliferation, DNA synthesis and collagen synthesis of cultured gingival fibroblasts derived from human nifedipine responders and non-responders. ( Akimoto, Y; Fujii, A; Matsumoto, H; Nakao, S; Teshigawara, H, 1994)
" Nifedipine is often used to control hypertension in kidney graft recipients."3.69Nifedipine aggravates cyclosporine A-induced gingival hyperplasia. ( Albers, N; Beier, C; Bohnhorst, B; Bökenkamp, A; Brodehl, J; Offner, G, 1994)
" The relative amounts of extracellular matrix macromolecules observed in 12 cases of gingival hyperplasia associated with the use of cyclosporin, hydantoin or nifedipine were compared with those obtained in a control group on the basis of histological and immunohistochemical investigations."3.69Changes in extracellular matrix macromolecules in human gingiva after treatment with drugs inducing gingival overgrowth. ( Bonnaure-Mallet, M; Godeau, GJ; Tricot-Doleux, S, 1995)
"This study investigated the prevalence of gingival hyperplasia in subjects who were undergoing treatment with a calcium channel blocker, nifedipine, in dentate and edentulous subjects."3.69Prevalence of nifedipine-induced gingival hyperplasia. ( Edson, RG; Lee, KK; Nery, EB; Pruthi, VK; Watson, J, 1995)
"A case of severe gingival overgrowth associated with combined drug therapy of cyclosporin A and nifedipine is reported."3.69Combined treatment approach to gingival overgrowth due to drug therapy. ( Darbar, UR; Hopper, C; Newman, HN; Speight, PM, 1996)
" Gingival overgrowth associated with cyclosporin (immunosuppressant agent) and nifedipine (calcium channel blocker) is well documented."3.69Periodontal management of gingival overgrowth in the heart transplant patient: a case report. ( Khocht, A; Schneider, LC, 1997)
"Gingival hyperplasia is an adverse reaction of nifedipine therapy."3.68Nifedipine-induced gingival hyperplasia. ( Barak, S; Ben Yehuda, A; Katz, J; Rotstein, I, 1992)
"We describe a case of gingival hyperplasia in a 36-year-old renal transplantation recipient treated with nifedipine for severe arterial hypertension."3.67Gingival hyperplasia by nifedipine. Report of a case. ( Bencini, PL; Crosti, C; Menni, S; Montagnino, G; Piccinno, R; Sala, F; Tarantino, A, 1985)
"We observed marked gingival hyperplasia, similar clinically and histologically to the hyperplasia caused by 5:5 sodium diphenylhydantoin (Dilantin) during the last 18 months in five patients treated by nifedipine."3.67Gingival hyperplasia caused by nifedipine--a preliminary report. ( Behar, S; Engelberg, IS; Kishon, Y; Ramon, Y, 1984)
"Gingival hyperplasia induced by nifedipine (Procardia), a calcium channel-blocking agent used as an anti-anginal drug, was studied."3.67Nifedipine-induced gingival hyperplasia. A histochemical and ultrastructural study. ( Howell, LP; Lucas, RM; Wall, BA, 1985)
"Nifedipine-induced gingival hyperplasia was first reported in 1984."3.67Nifedipine-induced gingival hyperplasia. ( Yusof, WZ, 1989)
" Animals in each group daily received NIF in dimethyl sulfoxide by gastric feeding at a dosage of 0 (control), 30, or 50 mg/kg body weight for 9 weeks."2.40Nifedipine-induced gingival overgrowth in rats: brief review and experimental study. ( Fu, E; Hsiao, CT; Hsieh, YD; Nieh, S; Shen, EC; Wikesjö, UM, 1998)
" In the majority of those patients for whom dosage reduction, or drug discontinuation or substitution is not possible, and for whom prophylactic measures have failed, surgical excision of gingival tissue remains the only treatment of choice."2.39Gingival enlargement induced by drugs. ( Berini, L; Brunet, L; Farré, M; Mendieta, C; Miranda, J, 1996)
"Twenty-day nifedipine treatment induced gingival hyperplasia accompanied with reduced salivary flow rate and concentrations of total protein, epidermal growth factor (EGF) and calcium in comparison with controls."1.33On the relation of nitric oxide to nifedipine-induced gingival hyperplasia and impaired submandibular glands function in rats in vivo. ( Abdollahi, M; Khorasani, R; Minaiee, B; Rezaie, A; Rezaie, S, 2005)
"Nifedipine-untreated and dimethylsulfoxide (DMSO)-treated animals served as control groups."1.32Effect of nifedipine on the expression of bcl-2 protein in rat gingiva. ( Handajani, J; Haniastuti, T; Santoso, AL; Sosroseno, W; Utoro, T, 2003)
"Gingival hyperplasia was not associated with any of the CsA-PK studied parameters."1.31Impact of cyclosporin A pharmacokinetics on the presence of side effects in pediatric renal transplantation. ( Arai Furusawa, E; Cavalcante, JS; David-Neto, E; Ianhez, LE; Lemos, FBC; Romano, P; Schwartzman, BS; Yagyu, EM, 2000)
"Treatment with nifedipine in rats led to the inducement of gingival hyperplasia and increase in the numbers of p53-positive gingival epithelial cells by a dose and frequency dependent mechanism, suggesting that p53 protein may play a crucial role in the regulation of nifedipine-induced gingival hyperplasia."1.31Effect of nifedipine on the expression of p53 protein in rat gingiva. ( Agustina, D; Agustiono, P; Haniastuti, T; Santoso, AS; Sosroseno, W, 2002)
"The incidence of gingival hyperplasia has been reported as 10%-20% in patients treated with calcium antagonists in the general population."1.30Incidence of gingival hyperplasia caused by calcium antagonists in continuous ambulatory peritoneal dialysis patients. ( Nakamoto, H; Okada, H; Shouda, J; Sugahara, S; Suzuki, H, 1999)
"Gingival hyperplasia was only weakly related to plaque and calculus but was unrelated to CsA dose (mg/kg/day), duration of CsA therapy (months), CsA blood or saliva levels (ng/ml), or the concurrent administration of a Nif or Dz."1.29Gingival hyperplasia in renal allograft recipients receiving cyclosporin-A and calcium antagonists. ( Francis, DM; Fullinfaw, R; Higgins, TJ; King, GN; Walker, RG; Wiesenfeld, D, 1993)
"Six children had enamel hypoplasia, three in permanent incisors and three in primary incisors."1.29Oral findings in children with liver transplants. ( Gordon, G; Hosey, MT; Kelly, DA; Shaw, L, 1995)
"The mechanism of gingival overgrowth associated with long-term use of nifedipine and of other drugs that affect calcium homoeostasis, such as cyclosporin and phenytoin, is unknown."1.28Gingival sequestration of nifedipine in nifedipine-induced gingival overgrowth. ( Ellis, JS; Idle, JR; Monkman, SC; Seymour, RA, 1992)
" Gingival changes in the nifedipine patients were not related to drug dosage or plaque scores."1.28The incidence and severity of nifedipine-induced gingival overgrowth. ( Barclay, S; Idle, JR; Seymour, RA; Thomason, JM, 1992)

Research

Studies (145)

TimeframeStudies, this research(%)All Research%
pre-199037 (25.52)18.7374
1990's86 (59.31)18.2507
2000's17 (11.72)29.6817
2010's4 (2.76)24.3611
2020's1 (0.69)2.80

Authors

AuthorsStudies
Reddy, SC1
Midha, N1
Chhabra, V1
Kumar, D1
Bohra, GK1
Asif, SM1
Shaik, N1
Barthunia, B1
Kaleem, SM1
Zakirulla, M1
Kota, MZ1
Baig, FAH1
van Montfort, M1
Huisman, L1
Brochet, MS1
Harry, M1
Morin, F1
Cohen, D1
Bhattacharyya, I1
Haniastuti, T2
Santoso, AS1
Agustiono, P1
Agustina, D1
Sosroseno, W2
Shimizu, Y1
Kataoka, M2
Seto, H1
Kido, J4
Nagata, T6
Handajani, J1
Santoso, AL1
Utoro, T1
Rezaie, S1
Rezaie, A1
Minaiee, B1
Khorasani, R1
Abdollahi, M1
Brkić, Z2
Hosey, MT1
Gordon, G1
Kelly, DA1
Shaw, L1
Bahamondes, C1
Godoy, J1
van der Wall, EE2
Tuinzing, DB2
Hes, J2
Lederman, D1
Lumerman, H1
Reuben, S1
Freedman, PD1
Ramon, Y1
Behar, S1
Kishon, Y1
Engelberg, IS2
Thomason, JM6
Seymour, RA9
Ellis, JS5
Kelly, PJ1
Parry, G1
Dark, J1
Idle, JR4
González Romero, EA1
López Sánchez, AF1
Granados Menéndez, MI1
Hernández Vallejo, G1
Butler, TJ2
Nery, EB1
Edson, RG1
Lee, KK1
Pruthi, VK1
Watson, J1
Harel-Raviv, M1
Eckler, M1
Lalani, K1
Raviv, E1
Gornitsky, M1
Ishida, H5
Kondoh, T1
Nishikawa, S4
Nakagawa, T1
Morisaki, I2
Oka, T2
Bonnaure-Mallet, M1
Tricot-Doleux, S1
Godeau, GJ1
Ramsdale, DR1
Morris, JL1
Hardy, P1
McKevitt, KM1
Irwin, CR1
Rees, TD1
Levine, RA1
Salerno, L1
Pepe, S1
Gullotti, D1
Iacò, V1
Rossmann, JA1
Ingles, E1
Brown, RS2
Bökenkamp, A1
Bohnhorst, B1
Beier, C1
Albers, N1
Offner, G1
Brodehl, J1
Zebrowski, EJ1
Pylypas, SP1
Odlum, O1
Johnson, RB1
Mathis, DE1
Scheetz, AP1
Naylor, CD1
Steele, RM1
Schuna, AA1
Schreiber, RT1
Fujii, A2
Matsumoto, H1
Nakao, S2
Teshigawara, H2
Akimoto, Y2
Bullon, P2
Machuca, G2
Martinez-Sahuquillo, A1
Rios, JV1
Rojas, J1
Lacalle, JR1
Rice, N1
Romanos, GE3
Schröter-Kermani, C2
Hinz, N2
Herrmann, D1
Strub, JR2
Bernimoulin, JP3
King, GN1
Fullinfaw, R1
Higgins, TJ1
Walker, RG1
Francis, DM1
Wiesenfeld, D1
O'Valle, F1
Mesa, F1
Aneiros, J1
Gómez-Morales, M1
Lucena, MA1
Ramírez, C1
Revelles, F1
Moreno, E1
Navarro, N1
Caballero, T1
Silverstein, LH2
Koch, JP2
Shatz, PC1
Lefkove, MD1
Garnick, JJ1
Singh, B1
Steflik, DE1
Hapak, L1
Brunet, L1
Miranda, J1
Farré, M1
Berini, L1
Mendieta, C1
Darbar, UR1
Hopper, C1
Speight, PM1
Newman, HN1
Lowry, LY1
Welbury, RR1
Waterhouse, PJ1
Hamilton, JR1
Saito, K3
Mori, S3
Iwakura, M1
Sakamoto, S3
Frieman, J1
Jackson, C1
Babich, S1
Deen-Duggins, L1
Fry, HR1
Clay, JR1
Turner, JR1
Westbrook, P1
Bednarczyk, EM1
Carlson, M1
Sheehan, H1
Bissada, NF1
Jorgensen, MG1
Khocht, A1
Schneider, LC1
Ciantar, M1
Santi, E1
Bral, M1
Shoieb, MA1
Fathy, LM1
Abu-el-Dahab, O1
el-Sherbiny, MM1
Botha, PJ1
Fu, E1
Nieh, S1
Hsiao, CT1
Hsieh, YD1
Wikesjö, UM1
Shen, EC1
Pilloni, A1
Camargo, PM1
Carere, M1
Carranza, FA1
Varga, E1
Mair, LH1
Nohl, F1
Ferrari, P1
Payne, VM1
Nakayama, J1
Koga, T1
Furue, M1
Steele, JG1
Robertson, P1
Tanda, N2
Keglevich, T1
Benedek, E1
Gera, I1
Türkmen, A1
Ak, G1
Furuncuoglu, Y1
Akar, U1
Seyhun, Y1
Türk, S1
Carin, M1
Sever, MS1
David-Neto, E1
Lemos, FBC1
Arai Furusawa, E1
Schwartzman, BS1
Cavalcante, JS1
Yagyu, EM1
Romano, P1
Ianhez, LE1
Shouda, J1
Nakamoto, H1
Sugahara, S1
Okada, H1
Suzuki, H1
Missouris, GG1
Kalaitzidis, RG1
Cappuccio, FP1
MacGregor, GA1
Das, SJ1
Olsen, I1
Morgan, JD1
Swarbrick, MJ1
Edwards, CM1
Donnelly, PK1
Houston, GD1
Thomas, DW1
Baboolal, K1
Subramanian, N1
Newcombe, RG1
Armas, JR1
Rojas, JL1
Jiménez, G1
Riley, CK1
Terezhalmy, GT1
James, JA1
Linden, GJ1
Monkman, SC1
Bhatia, RS1
Barclay, S1
Sauget, P1
Monteil, RA1
Morand, P1
Loubiere, R1
Lapalus, P1
Haudebourg, C1
Royo, M1
Arto, A1
Tam, IM1
Wandres, DL1
Burkes, EJ1
Jacoway, JR1
Stevens, DT1
Braddock, ME1
Katz, J1
Rotstein, I1
Ben Yehuda, A1
Barak, S3
Beaver, WT1
Bottomley, WK1
Hancock, RH1
Swan, RH1
Tanaka, S1
Omata, H1
Shibutani, J1
Nakano, Y1
Kaneko, K1
Kawana, T1
Braun, T1
Sponholz, F1
Sponholz, H1
MacCarthy, D1
Claffey, N1
García Bernal, G1
Collado, A1
Cerón, A1
Goffin, M1
Mohapatra, BN1
Kar, BC1
Das, P1
Gupta, AK1
Gupta, P1
Tada, H1
Hamasaki, A3
Kasahara, S1
Wakano, Y3
Bosker, H1
Jordan, RD1
Sindet-Pedersen, S1
Koole, R1
Kleber, BM1
Strahlendorf, F1
Marcos Sánchez, F2
Arranz Nieto, MJ1
Celdrán Gil, J2
Durán Pérez Navarro, A1
Mellado Calvo, N1
Durán, A1
Sanz Cantalapiedra, R1
Dalfó Baqué, A1
Martín Arias, LH1
Carvajal García-Pando, A1
Tagawa, T1
Nakamura, H1
Murata, M1
Zlotogorski, A2
Nyska, A3
Katayama, H1
Kinoshita, Y1
Kaneko, M1
Suzuki, N1
Kakami, K1
Takai, Y1
Doria, G1
Cangemi, F1
Gulizia, M1
Lo Giudice, P1
Circo, A1
Bencini, PL1
Crosti, C1
Sala, F2
Montagnino, G1
Tarantino, A1
Menni, S1
Piccinno, R1
Lundergan, WP1
Andronikaki-Faldami, A1
Nikolatou, O1
Nikolopoulou-Papaconstantinou, A1
Psaroulis, K1
De Camargo, PM1
Yusof, WZ2
Matarasso, S1
Vaia, E1
Caputo, G1
Riccitiello, F1
Nyska, M2
Sela, M2
Gotsman, M1
Ferrés, E1
López Colomés, JL1
Moreno, A1
Villena, J1
Veraldi, S2
Piferi, M2
Marini, D2
Slavin, J1
Taylor, J1
Chicco, GN1
Fletcher, P1
Kaplan, I1
Silvestri, E1
Bencini, L1
Puolijoki, H2
Siitonen, L2
Saha, H2
Suojanen, I2
Raman, PG1
Mishra, VN1
Singh, D1
Waner, T1
Pirak, M1
Galiano, A1
Tejerina Lobo, JM1
Mencia Fernandez, C1
Martos Molino, F1
Simarro Martin-Ambrosio, E1
Jones, CM1
Chomette, G1
Auriol, M1
Szpirglas, H1
Ragot, J1
Thomas, D1
Cabrol, C1
Vaillant, JM1
Butler, RT1
Kalkwarf, KL1
Kaldahl, WB1
Glenert, U1
Hansen, HJ1
Pindborg, JJ1
Lainson, PA1
Hiss, J1
Ciancio, SG1
Pignanelli, M1
Mattei, R1
Ueno, A1
Koda, N2
Gómez-Fernández, P1
Pérez, R1
Gallego, P1
Almaraz, M1
Scardi, S1
Pivotti, F1
Flaminio, R1
Lucas, RM1
Howell, LP1
Wall, BA1
Masuda, T1
Kagawa, K1
Ebuchi, Y1

Reviews

20 reviews available for nifedipine and Gingival Hyperplasia

ArticleYear
Nifedipine-induced gingival hyperplasia. A comprehensive review and analysis.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 1995, Volume: 79, Issue:6

    Topics: Calcium; Female; Gingival Hyperplasia; Gingivoplasty; Humans; Middle Aged; Nifedipine

1995
Systematic drugs as a risk factor for periodontal disease initiation and progression.
    Compendium (Newtown, Pa.), 1995, Volume: 16, Issue:1

    Topics: Calcium Channel Blockers; Cyclosporine; Female; Fibromatosis, Gingival; Gingival Hyperplasia; Gonada

1995
Oral and dental problems in the organ transplant patient.
    Dental update, 1994, Volume: 21, Issue:5

    Topics: Anti-Bacterial Agents; Cyclosporine; Dental Care for Chronically Ill; Gingival Hyperplasia; Humans;

1994
Pathogenesis of drug-induced gingival overgrowth. A review of studies in the rat model.
    Journal of periodontology, 1996, Volume: 67, Issue:5

    Topics: Age Factors; Animals; Anticonvulsants; Calcium Channel Blockers; Cyclosporine; Dental Plaque; Diseas

1996
Periodontal management of nifedipine-induced gingival overgrowth: a case report and review of the pertinent literature.
    Oral health, 1994, Volume: 84, Issue:10

    Topics: Calcium Channel Blockers; Gingival Hyperplasia; Humans; Male; Middle Aged; Nifedipine; Periodontitis

1994
Gingival enlargement induced by drugs.
    Drug safety, 1996, Volume: 15, Issue:3

    Topics: Anticonvulsants; Calcium Channel Blockers; Cyclosporine; Gingival Hyperplasia; Humans; Immunosuppres

1996
Nifedipine-associated gingival overgrowth: a survey of the literature and report of four cases.
    Quintessence international (Berlin, Germany : 1985), 1996, Volume: 27, Issue:3

    Topics: Adult; Aged; Calcium Channel Blockers; Female; Gingival Hyperplasia; Humans; Male; Middle Aged; Nife

1996
Nifedipine-induced gingival overgrowth: remission following non-surgical therapy.
    Dental update, 1996, Volume: 23, Issue:9

    Topics: Calcium Channel Blockers; Combined Modality Therapy; Dental Plaque; Denture, Partial, Removable; Gin

1996
Drug-induced gingival hyperplasia and its management--a literature review.
    The Journal of the Dental Association of South Africa = Die Tydskrif van die Tandheelkundige Vereniging van Suid-Afrika, 1997, Volume: 52, Issue:11

    Topics: Anticonvulsants; Calcium Channel Blockers; Clinical Protocols; Cyclosporine; Gingival Hyperplasia; H

1997
Nifedipine-induced gingival overgrowth in rats: brief review and experimental study.
    Journal of periodontology, 1998, Volume: 69, Issue:7

    Topics: Analysis of Variance; Animals; Body Weight; Calcium Channel Blockers; Disease Models, Animal; Dose-R

1998
[Clinical experience with the treatment of gingival hyperplasia induced by calcium channel blocking agents].
    Fogorvosi szemle, 1999, Volume: 92, Issue:12

    Topics: Calcium Channel Blockers; Gingival Hyperplasia; Gingivectomy; Humans; Nifedipine; Oral Hygiene

1999
The patient with hypertension.
    Quintessence international (Berlin, Germany : 1985), 2001, Volume: 32, Issue:9

    Topics: Anesthesia, Dental; Calcium Channel Blockers; Coronary Disease; Dental Care for Chronically Ill; Eme

2001
[Gingival hyperplasia secondary to the use of calcium antagonists: analysis].
    Journal de biologie buccale, 1992, Volume: 20, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Diltiazem; Epithelium; Female; Fibroblasts; Gingiva; Gingival Hyperp

1992
Calcium-channel blockers and gingival hyperplasia.
    The Annals of pharmacotherapy, 1992, Volume: 26, Issue:2

    Topics: Aged; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; Female; Gingival Hyperplasia; Hu

1992
On the mechanism of drug-induced gingival hyperplasia.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1991, Volume: 20, Issue:5

    Topics: Dental Plaque; Diltiazem; Epidermal Growth Factor; Fibroblasts; Folic Acid; Gingival Hyperplasia; Gl

1991
[Gingival hyperplasia in a heart transplant patient treated with cyclosporin A and nifedipine].
    Revue belge de medecine dentaire, 1991, Volume: 46, Issue:2

    Topics: Adolescent; Cyclosporins; Gingival Hyperplasia; Heart Transplantation; Humans; Male; Nifedipine

1991
Calcium channel blockers and gingival overgrowth.
    British dental journal, 1991, May-25, Volume: 170, Issue:10

    Topics: Calcium Channel Blockers; Cyclosporins; Diltiazem; Fibroblasts; Gingival Hyperplasia; Humans; Nifedi

1991
Cyclosporin- and nifedipine-induced gingival enlargement: an overview.
    The Journal of the Western Society of Periodontology/Periodontal abstracts, 1989, Volume: 37, Issue:2

    Topics: Cyclosporins; Gingival Hyperplasia; Humans; Nifedipine

1989
[Hyperthrophic-hyperplastic gingival diseases. Etiopathogenic, clinical assessment and diagnostic guide].
    Minerva stomatologica, 1989, Volume: 38, Issue:5

    Topics: Anticonvulsants; Cyclosporins; Fibromatosis, Gingival; Gingival Hyperplasia; Gingival Hypertrophy; G

1989
Nifedipine-induced gingival hyperplasia: case reports and literature review.
    Israel journal of medical sciences, 1989, Volume: 25, Issue:8

    Topics: Gingival Hyperplasia; Humans; Male; Middle Aged; Nifedipine

1989

Trials

6 trials available for nifedipine and Gingival Hyperplasia

ArticleYear
Calcium antagonist-induced gingival hyperplasia.
    Annals of internal medicine, 1994, Apr-15, Volume: 120, Issue:8

    Topics: Adult; Aged; Calcium Channel Blockers; Cross-Sectional Studies; Diltiazem; Gingival Hyperplasia; Hum

1994
Regression of nifedipine-induced gingival hyperplasia following switch to a same class calcium channel blocker, isradipine.
    Journal of periodontology, 1997, Volume: 68, Issue:7

    Topics: Adult; Aged; Antihypertensive Agents; Biopsy; Calcium Channel Blockers; Dental Plaque Index; Evaluat

1997
Surgical treatment of cyclosporine A- and nifedipine-induced gingival enlargement: gingivectomy versus periodontal flap.
    Journal of periodontology, 1998, Volume: 69, Issue:7

    Topics: Adolescent; Adult; Calcium Channel Blockers; Child; Cyclosporine; Female; Gingival Hyperplasia; Ging

1998
Long-term efficacy and adverse event of nifedipine sustained-release tablets for cyclosporin A-induced hypertension in patients with psoriasis.
    European journal of dermatology : EJD, 1998, Volume: 8, Issue:8

    Topics: Adult; Aged; Blood Pressure Determination; Calcium Channel Blockers; Cyclosporine; Delayed-Action Pr

1998
[Clinical experience with the treatment of gingival hyperplasia induced by calcium channel blocking agents].
    Fogorvosi szemle, 1999, Volume: 92, Issue:12

    Topics: Calcium Channel Blockers; Gingival Hyperplasia; Gingivectomy; Humans; Nifedipine; Oral Hygiene

1999
Cyclosporin, nifedipine and gingival hyperplasia: a randomized controlled study.
    Transplant international : official journal of the European Society for Organ Transplantation, 1994, Volume: 7 Suppl 1

    Topics: Calcium Channel Blockers; Cyclosporine; Drug Interactions; Gingival Hyperplasia; Gingivectomy; Human

1994

Other Studies

120 other studies available for nifedipine and Gingival Hyperplasia

ArticleYear
Amlodipine Induced Gum Hypertrophy: A Rare Case Report.
    Current drug safety, 2022, Volume: 17, Issue:3

    Topics: Aged; Amlodipine; Calcium Channel Blockers; Gingival Hyperplasia; Gingival Overgrowth; Humans; Hyper

2022
Nifedipine induced gingival enlargement in an edentulous patient: a case report with one year follow up.
    BMC oral health, 2018, 12-27, Volume: 18, Issue:1

    Topics: Aged; Calcium Channel Blockers; Gingiva; Gingival Hyperplasia; Gingivectomy; Humans; Hypertension; M

2018
[A woman with gingival hyperplasia].
    Nederlands tijdschrift voor geneeskunde, 2014, Volume: 159

    Topics: Aged; Calcium Channel Blockers; Female; Gingival Hyperplasia; Humans; Incidence; Nifedipine; Prevale

2014
Nifedipine Induced Gingival Hyperplasia in Pregnancy: A Case Report.
    Current drug safety, 2017, Volume: 12, Issue:1

    Topics: Antihypertensive Agents; Calcium Channel Blockers; Female; Gingival Hyperplasia; Humans; Nifedipine;

2017
Case of the month: drug-induced hyperplasia.
    Today's FDA : official monthly journal of the Florida Dental Association, 2008, Volume: 20, Issue:3

    Topics: Adult; Cyclosporine; Diagnosis, Differential; Female; Gingival Hyperplasia; Humans; Nifedipine; Phen

2008
Oral pathology quiz # 75. Case number 4. Systemic medication.
    Journal of the New Jersey Dental Association, 2012,Spring, Volume: 83, Issue:2

    Topics: Anticonvulsants; Cyclosporine; Diagnosis, Differential; Gingival Hyperplasia; Humans; Immunosuppress

2012
Effect of nifedipine on the expression of p53 protein in rat gingiva.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2002, Volume: 56, Issue:5

    Topics: Animals; Gingiva; Gingival Hyperplasia; Male; Nifedipine; Rats; Rats, Sprague-Dawley; Tumor Suppress

2002
Nifedipine induces gingival epithelial hyperplasia in rats through inhibition of apoptosis.
    Journal of periodontology, 2002, Volume: 73, Issue:8

    Topics: Animals; Antimetabolites; Apoptosis; Bromodeoxyuridine; Calcium Channel Blockers; Cell Division; Cel

2002
Effect of nifedipine on the expression of bcl-2 protein in rat gingiva.
    Clinical oral investigations, 2003, Volume: 7, Issue:1

    Topics: Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; Epithelial Cells; Gingiva; Ging

2003
On the relation of nitric oxide to nifedipine-induced gingival hyperplasia and impaired submandibular glands function in rats in vivo.
    Fundamental & clinical pharmacology, 2005, Volume: 19, Issue:1

    Topics: Animals; Arginine; Calcium; Calcium Channel Blockers; Epidermal Growth Factor; Gingival Hyperplasia;

2005
[Histopathologic investigations of nifedipine-induced gingival hyperplasia in Wistar rats].
    Vojnosanitetski pregled, 2005, Volume: 62, Issue:3

    Topics: Animals; Calcium Channel Blockers; Gingiva; Gingival Hyperplasia; Male; Nifedipine; Periodontium; Ra

2005
Oral findings in children with liver transplants.
    International journal of paediatric dentistry, 1995, Volume: 5, Issue:1

    Topics: Adolescent; Biliary Atresia; Child; Child, Preschool; Cyclosporine; Dental Enamel Hypoplasia; Gingiv

1995
[Histometric analysis of gingival hyperplasia in Wistar rats during nifedipine administration].
    Vojnosanitetski pregled, 2007, Volume: 64, Issue:1

    Topics: Animals; Calcium Channel Blockers; Gingiva; Gingival Hyperplasia; Male; Nifedipine; Rats; Rats, Wist

2007
[Cyclosporine-induced gingival hyperplasia: report of one case].
    Revista medica de Chile, 2007, Volume: 135, Issue:3

    Topics: Biofilms; Calcium Channel Blockers; Cyclosporine; Gingiva; Gingival Hyperplasia; Humans; Immunosuppr

2007
[Gingival hyperplasia: a possible side effect of nifedipine].
    Nederlands tijdschrift voor geneeskunde, 1984, Oct-13, Volume: 128, Issue:41

    Topics: Adult; Female; Gingival Hyperplasia; Humans; Hypertension, Pulmonary; Nifedipine

1984
Gingival hyperplasia associated with nifedipine therapy. Report of a case.
    Oral surgery, oral medicine, and oral pathology, 1984, Volume: 57, Issue:6

    Topics: Female; Gingival Hyperplasia; Gingivectomy; Humans; Middle Aged; Nifedipine

1984
Gingival hyperplasia caused by nifedipine--a preliminary report.
    International journal of cardiology, 1984, Volume: 5, Issue:2

    Topics: Aged; Coronary Artery Bypass; Female; Gingiva; Gingival Hyperplasia; Humans; Hypertension; Male; Mid

1984
Iatrogenic gingival overgrowth in cardiac transplantation.
    Journal of periodontology, 1995, Volume: 66, Issue:8

    Topics: Adolescent; Adult; Age Factors; Calcium Channel Blockers; Cyclosporine; Drug Synergism; Female; Ging

1995
[Drug-induced gingival hyperplasia].
    Atencion primaria, 1995, Oct-15, Volume: 16, Issue:6

    Topics: Adult; Calcium Channel Blockers; Child; Cyclosporins; Gingival Hyperplasia; Humans; Hydantoins; Nife

1995
Periodontal variables affecting nifedipine sequestration in gingival crevicular fluid.
    Journal of periodontal research, 1995, Volume: 30, Issue:4

    Topics: Adult; Calcium Channel Blockers; Confounding Factors, Epidemiologic; Dental Plaque Index; Dose-Respo

1995
Prevalence of nifedipine-induced gingival hyperplasia.
    Journal of periodontology, 1995, Volume: 66, Issue:7

    Topics: Age Factors; Biopsy; Calcium Channel Blockers; Collagen; Connective Tissue; Dentition; Epithelium; F

1995
Factors influencing nifedipine-induced gingival overgrowth in rats.
    Journal of periodontology, 1995, Volume: 66, Issue:5

    Topics: Age Factors; Analysis of Variance; Animal Feed; Animals; Dose-Response Relationship, Drug; Female; G

1995
Changes in extracellular matrix macromolecules in human gingiva after treatment with drugs inducing gingival overgrowth.
    Archives of oral biology, 1995, Volume: 40, Issue:5

    Topics: Collagen; Cyclosporine; Elastic Tissue; Elastin; Extracellular Matrix; Extracellular Matrix Proteins

1995
Gingival hyperplasia with nifedipine.
    British heart journal, 1995, Volume: 73, Issue:2

    Topics: Gingival Hyperplasia; Humans; Male; Middle Aged; Nifedipine

1995
Phenotypic differences in growth, matrix synthesis and response to nifedipine between fibroblasts derived from clinically healthy and overgrown gingival tissue.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1995, Volume: 24, Issue:2

    Topics: Analysis of Variance; Collagen; Female; Fibroblasts; Gingival Hyperplasia; Humans; Male; Middle Aged

1995
[Gingival hyperplasia induced by amlodipine].
    La Clinica terapeutica, 1995, Volume: 146, Issue:4

    Topics: Adult; Amlodipine; Calcium Channel Blockers; Gingival Hyperplasia; Humans; Hypertension; Male; Nifed

1995
Multimodal treatment of drug-induced gingival hyperplasia in a kidney transplant patient.
    Compendium (Newtown, Pa.), 1994, Volume: 15, Issue:10

    Topics: Adult; Chlorhexidine; Cyclosporine; Dental Care for Chronically Ill; Dental Plaque; Drug Interaction

1994
Nifedipine aggravates cyclosporine A-induced gingival hyperplasia.
    Pediatric nephrology (Berlin, Germany), 1994, Volume: 8, Issue:2

    Topics: Adolescent; Adult; Azathioprine; Cyclosporine; Drug Therapy, Combination; Female; Gingival Hyperplas

1994
Comparative metabolism of 3H-glucosamine by fibroblast populations exposed to cyclosporine.
    Journal of periodontology, 1994, Volume: 65, Issue:6

    Topics: Adult; Cell Count; Cells, Cultured; Chronic Disease; Cyclosporine; Extracellular Matrix; Fibroblasts

1994
Calcium channel antagonists and gingival hyperplasia.
    Annals of internal medicine, 1994, Oct-15, Volume: 121, Issue:8

    Topics: Confounding Factors, Epidemiologic; Gingival Hyperplasia; Humans; Nifedipine

1994
Calcium channel antagonists and gingival hyperplasia.
    Annals of internal medicine, 1994, Oct-15, Volume: 121, Issue:8

    Topics: Gingival Hyperplasia; Humans; Nifedipine; Periodontal Diseases

1994
Effect of calcium-channel blockers on cell proliferation, DNA synthesis and collagen synthesis of cultured gingival fibroblasts derived from human nifedipine responders and non-responders.
    Archives of oral biology, 1994, Volume: 39, Issue:2

    Topics: Adult; Aged; Calcium Channel Blockers; Cell Count; Cell Division; Cells, Cultured; Collagen; DNA; Fe

1994
Clinical assessment of gingival hyperplasia in patients treated with nifedipine.
    Journal of clinical periodontology, 1994, Volume: 21, Issue:4

    Topics: Dental Plaque Index; Dose-Response Relationship, Drug; Female; Gingival Hemorrhage; Gingival Hyperpl

1994
The prevalence and severity of cyclosporin and nifedipine-induced gingival overgrowth.
    Journal of clinical periodontology, 1993, Volume: 20, Issue:1

    Topics: Adult; Cohort Studies; Cyclosporine; Dental Plaque Index; Drug Combinations; Female; Gingival Hemorr

1993
Extracellular matrix analysis of nifedipine-induced gingival overgrowth: immunohistochemical distribution of different collagen types as well as the glycoprotein fibronectin.
    Journal of periodontal research, 1993, Volume: 28, Issue:1

    Topics: Adult; Basement Membrane; Collagen; Extracellular Matrix; Female; Fibronectins; Fluorescent Antibody

1993
Immunohistochemical distribution of extracellular matrix proteins as a diagnostic parameter in healthy and diseased gingiva.
    Journal of periodontology, 1993, Volume: 64, Issue:2

    Topics: Adult; Aged; Collagen; Cyclosporine; Extracellular Matrix Proteins; Female; Fibronectins; Fluorescen

1993
Gingival hyperplasia in renal allograft recipients receiving cyclosporin-A and calcium antagonists.
    Journal of clinical periodontology, 1993, Volume: 20, Issue:4

    Topics: Adult; Cross-Sectional Studies; Cyclosporine; Dental Calculus; Dental Plaque Index; Diltiazem; Drug

1993
Gingival overgrowth induced by nifedipine and cyclosporin A. Clinical and morphometric study with image analysis.
    Journal of clinical periodontology, 1995, Volume: 22, Issue:8

    Topics: Adult; Calcium Channel Blockers; Case-Control Studies; Cyclosporine; Drug Synergism; Female; Follow-

1995
Nifedipine-induced gingival hyperplasia.
    American family physician, 1996, Volume: 53, Issue:4

    Topics: Calcium Channel Blockers; Gingival Hyperplasia; Humans; Nifedipine

1996
Nifedipine-induced gingival enlargement around dental implants: a clinical report.
    The Journal of oral implantology, 1995, Volume: 21, Issue:2

    Topics: Animals; Calcium Channel Blockers; Cats; Dental Care for Chronically Ill; Dental Implants; Female; G

1995
Combined treatment approach to gingival overgrowth due to drug therapy.
    Journal of clinical periodontology, 1996, Volume: 23, Issue:10

    Topics: Blood Loss, Surgical; Calcium Channel Blockers; Carbon Dioxide; Cyclosporine; Gingival Hemorrhage; G

1996
Gingival overgrowth in paediatric cardiac transplant patients: a study of 19 patients aged between 2 and 16 years.
    International journal of paediatric dentistry, 1995, Volume: 5, Issue:4

    Topics: Adolescent; Calcium Channel Blockers; Child; Child, Preschool; Cyclosporine; Dental Care for Chronic

1995
Immunohistochemical localization of transforming growth factor beta, basic fibroblast growth factor and heparan sulphate glycosaminoglycan in gingival hyperplasia induced by nifedipine and phenytoin.
    Journal of periodontal research, 1996, Volume: 31, Issue:8

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Calcium Channel Blockers; Cell Count; Coloring Agents; Fem

1996
Alternative protocol.
    The New York state dental journal, 1996, Volume: 62, Issue:10

    Topics: Calcium Channel Blockers; Chlorhexidine; Drug Administration Schedule; Gingival Hyperplasia; Humans;

1996
Gingival hyperplasia: interaction between cyclosporin A and nifedipine? A case report.
    The New York state dental journal, 1997, Volume: 63, Issue:1

    Topics: Calcium Channel Blockers; Cyclosporine; Drug Synergism; Female; Gingival Hyperplasia; Gingival Pocke

1997
Prevalence of amlodipine-related gingival hyperplasia.
    Journal of periodontology, 1997, Volume: 68, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Calcium Channel Blockers; Dental Plaque Index; Female; G

1997
Periodontal management of gingival overgrowth in the heart transplant patient: a case report.
    Journal of periodontology, 1997, Volume: 68, Issue:11

    Topics: Calcium Channel Blockers; Candidiasis, Oral; Connective Tissue; Cyclosporine; Epithelium; Fibrosis;

1997
Effect of treatment on cyclosporine- and nifedipine-induced gingival enlargement: clinical and histologic results.
    The International journal of periodontics & restorative dentistry, 1998, Volume: 18, Issue:1

    Topics: Adult; Aged; Anti-Infective Agents, Local; Chlorhexidine; Combined Modality Therapy; Cyclosporine; D

1998
A clinical and histological comparative study of the effect of nifedipine and phenytion on human gingiva.
    Egyptian dental journal, 1993, Volume: 39, Issue:4

    Topics: Anticonvulsants; Biopsy; Calcium Channel Blockers; Gingiva; Gingival Hyperplasia; Humans; Nifedipine

1993
Medication influencing the development of gingival overgrowth in renal transplant patients.
    Transplantation proceedings, 1998, Volume: 30, Issue:5

    Topics: Cyclosporine; Gingiva; Gingival Hyperplasia; Gingivitis; Humans; Immunosuppressive Agents; Kidney Fa

1998
[Drug-induced gingival hyperplasia].
    Therapeutische Umschau. Revue therapeutique, 1998, Volume: 55, Issue:9

    Topics: Adult; Antihypertensive Agents; Calcium Channel Blockers; Cyclosporine; Drug Therapy, Combination; F

1998
Re: Periodontal management of gingival overgrowth in the heart transplant patient: a case report (1997;68:1140-1146)
    Journal of periodontology, 1998, Volume: 69, Issue:11

    Topics: Adult; Azathioprine; Calcium Channel Blockers; Candidiasis, Oral; Chlorhexidine; Cyclosporine; Gingi

1998
Prevalence of gingival overgrowth induced by calcium channel blockers: a community-based study.
    Journal of periodontology, 1999, Volume: 70, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Analysis of Variance; Calcium Channel Blockers; Dental P

1999
Gingival hyperplasia due to calcium antagonists.
    Prescrire international, 1998, Volume: 7, Issue:34

    Topics: Calcium Channel Blockers; Dihydropyridines; Diltiazem; Gingival Hyperplasia; Humans; Nifedipine; Ver

1998
Expression of p53 protein and Ki-67 antigen in gingival hyperplasia induced by nifedipine and phenytoin.
    Journal of periodontology, 1999, Volume: 70, Issue:6

    Topics: Adolescent; Adult; Anticonvulsants; Biomarkers, Tumor; Calcium Channel Blockers; Carcinoma, Squamous

1999
Relationship between gingival hyperplasia and class II histocompatibility antigens in renal transplant recipients.
    Nephron, 2000, Volume: 84, Issue:1

    Topics: Adult; Calcium Channel Blockers; Cyclosporine; Female; Gingival Hyperplasia; Histocompatibility Anti

2000
Impact of cyclosporin A pharmacokinetics on the presence of side effects in pediatric renal transplantation.
    Journal of the American Society of Nephrology : JASN, 2000, Volume: 11, Issue:2

    Topics: Adolescent; Adult; Antihypertensive Agents; Child; Cyclosporine; Female; Gingival Hyperplasia; Hand;

2000
Incidence of gingival hyperplasia caused by calcium antagonists in continuous ambulatory peritoneal dialysis patients.
    Advances in peritoneal dialysis. Conference on Peritoneal Dialysis, 1999, Volume: 15

    Topics: Adult; Amlodipine; Calcium Channel Blockers; Cardiovascular Diseases; Felodipine; Female; Gingival H

1999
Immunolocalizaiton of c-Myc and bcl-2 proto-oncogene products in gingival hyperplasia induced by nifedipine and phenytoin.
    Journal of periodontology, 2000, Volume: 71, Issue:1

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Calcium Channel Blockers; Epithelial Cells; Epithelium; Fe

2000
Gingival hyperplasia caused by calcium channel blockers.
    Journal of human hypertension, 2000, Volume: 14, Issue:2

    Topics: Calcium Channel Blockers; Gingival Hyperplasia; Humans; Male; Middle Aged; Nifedipine

2000
Keratinocyte growth factor is upregulated by the hyperplasia-inducing drug nifedipine.
    Cytokine, 2000, Volume: 12, Issue:10

    Topics: Antihypertensive Agents; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Epitop

2000
Oral pathology case of the quarter.
    Journal - Oklahoma Dental Association, 2001,Winter, Volume: 91, Issue:3

    Topics: Angina Pectoris; Calcium Channel Blockers; Diagnosis, Differential; Gingival Hyperplasia; Gingivitis

2001
Cyclosporin A-induced gingival overgrowth is unrelated to allograft function in renal transplant recipients.
    Journal of clinical periodontology, 2001, Volume: 28, Issue:7

    Topics: Adolescent; Adult; Aged; Azathioprine; Calcium Channel Blockers; Child; Child, Preschool; Creatinine

2001
The gingival inflammatory infiltrate in cardiac patients treated with calcium antagonists.
    Journal of clinical periodontology, 2001, Volume: 28, Issue:10

    Topics: Analysis of Variance; Calcium Channel Blockers; Case-Control Studies; Chi-Square Distribution; Dilti

2001
Nifedipine-induced gingival hyperplasia.
    Dental update, 1992, Volume: 19, Issue:10

    Topics: Aged; Female; Gingival Hyperplasia; Humans; Nifedipine

1992
Gingival sequestration of nifedipine in nifedipine-induced gingival overgrowth.
    Lancet (London, England), 1992, Jun-06, Volume: 339, Issue:8806

    Topics: Gingiva; Gingival Hyperplasia; Humans; Male; Nifedipine

1992
Nifedipine induced reversible gingival hyperplasia.
    The Journal of the Association of Physicians of India, 1992, Volume: 40, Issue:7

    Topics: Female; Gingival Hyperplasia; Humans; Hypertension; India; Middle Aged; Nifedipine

1992
Distribution of fibronectin in healthy, inflamed and drug-induced gingival hyperplasia.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1992, Volume: 21, Issue:6

    Topics: Actin Cytoskeleton; Adult; Connective Tissue; Connective Tissue Cells; Cyclosporine; Dental Plaque;

1992
The incidence and severity of nifedipine-induced gingival overgrowth.
    Journal of clinical periodontology, 1992, Volume: 19, Issue:5

    Topics: Atenolol; Dental Plaque Index; Female; Gingival Hyperplasia; Gingival Pocket; Humans; Incidence; Mal

1992
[Calcium antagonists and gingival hyperplasia].
    Atencion primaria, 1992, Jun-01, Volume: 9, Issue:9

    Topics: Adult; Gingival Hyperplasia; Humans; Male; Nifedipine

1992
Nifedipine-induced gingival hyperplasia.
    The Journal of the Tennessee Dental Association, 1992, Volume: 72, Issue:2

    Topics: Gingival Hyperplasia; Humans; Male; Middle Aged; Nifedipine

1992
Nifedipine-induced gingival hyperplasia.
    Annals of dentistry, 1992,Summer, Volume: 51, Issue:1

    Topics: Adult; Angina Pectoris; Female; Gingival Hemorrhage; Gingival Hyperplasia; Humans; Male; Middle Aged

1992
Nifedipine-induced gingival overgrowth. Report of a case treated by controlling plaque.
    Journal of clinical periodontology, 1992, Volume: 19, Issue:1

    Topics: Dental Calculus; Dental Plaque; Dental Scaling; Gingival Hyperplasia; Humans; Male; Middle Aged; Nif

1992
Gingival hyperplasia induced by nifedipine.
    The Journal of Nihon University School of Dentistry, 1991, Volume: 33, Issue:3

    Topics: Aged; Female; Gingival Hyperplasia; Humans; Male; Middle Aged; Nifedipine

1991
[Side effects of the immunsuppressive cyclosporin A in dentistry].
    Deutsche Stomatologie (Berlin, Germany : 1990), 1991, Volume: 41, Issue:4

    Topics: Adult; Cyclosporine; Female; Gingival Hyperplasia; Humans; Kidney Transplantation; Male; Middle Aged

1991
Fibrous hyperplasia of the gingiva in organ transplant patients.
    Journal of the Irish Dental Association, 1991, Volume: 37, Issue:1

    Topics: Adult; Cyclosporins; Dental Care for Disabled; Gingival Hyperplasia; Gingivectomy; Heart Transplanta

1991
[Gingival hyperplasia as an adverse reaction to nifedipine].
    Atencion primaria, 1991, Volume: 8, Issue:3

    Topics: Gingival Hyperplasia; Humans; Nifedipine

1991
Nifedipine-induced gum hyperplasia.
    The Journal of the Association of Physicians of India, 1991, Volume: 39, Issue:6

    Topics: Adult; Female; Gingival Hyperplasia; Humans; Hypertension; Nifedipine

1991
Nifedipine-induced gingival hyperplasia.
    The Journal of the Association of Physicians of India, 1991, Volume: 39, Issue:6

    Topics: Aged; Aged, 80 and over; Angina Pectoris; Female; Gingival Hyperplasia; Humans; Hypertension; Male;

1991
Nifedipine-induced gingival hyperplasia: a clinical and in vitro study.
    Journal of periodontology, 1991, Volume: 62, Issue:1

    Topics: Cell Division; Cells, Cultured; Collagen; Connective Tissue; Female; Fibroblasts; Gingival Hyperplas

1991
The transmandibular implant: a 13-year survey of its use.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1991, Volume: 49, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Dental Implantation, Endosseous; Female; Follow-Up Studies; Gingival

1991
[Clinical aspects of gingival hyperplasia].
    Parodontologie (Berlin, Germany), 1990, Volume: 1, Issue:2

    Topics: Cyclosporins; Gingival Hyperplasia; Humans; Hydantoins; Nifedipine

1990
[Gingival hyperplasia induced by nifedipine].
    Anales de medicina interna (Madrid, Spain : 1984), 1990, Volume: 7, Issue:4

    Topics: Gingival Hyperplasia; Humans; Male; Middle Aged; Nifedipine

1990
[Gingival hyperplasia and nifedipine].
    Atencion primaria, 1990, Volume: 7, Issue:10

    Topics: Female; Gingival Hyperplasia; Humans; Hypertension; Middle Aged; Nifedipine

1990
[Gingival hyperplasia produced by nifedipine].
    Atencion primaria, 1990, Volume: 7, Issue:2

    Topics: Delayed-Action Preparations; Gingival Hyperplasia; Humans; Male; Middle Aged; Nifedipine; Time Facto

1990
Marked gingival hyperplasia induced by nifedipine.
    International journal of oral and maxillofacial surgery, 1990, Volume: 19, Issue:2

    Topics: Female; Gingival Hyperplasia; Humans; Hypertension; Middle Aged; Nifedipine

1990
A case of marked gingival hyperplasia induced by nifedipine.
    International journal of oral and maxillofacial surgery, 1990, Volume: 19, Issue:5

    Topics: Gingival Hyperplasia; Humans; Nifedipine

1990
[A case of gingival hyperplasia induced by nifedipine].
    Aichi Gakuin Daigaku Shigakkai shi, 1990, Volume: 28, Issue:2

    Topics: Gingival Hyperplasia; Humans; Male; Middle Aged; Nifedipine

1990
[3 cases of gingival hyperplasia during nifedipine therapy].
    Minerva cardioangiologica, 1990, Volume: 38, Issue:3

    Topics: Adult; Gingival Hyperplasia; Humans; Male; Middle Aged; Nifedipine; Time Factors

1990
Gingival hyperplasia by nifedipine. Report of a case.
    Acta dermato-venereologica, 1985, Volume: 65, Issue:4

    Topics: Adult; Gingival Hyperplasia; Humans; Hypertension, Renal; Kidney Transplantation; Male; Nifedipine

1985
Drug-induced gingival enlargements.
    Journal of the California Dental Association, 1989, Volume: 17, Issue:6

    Topics: Adult; Cyclosporins; Gingival Hyperplasia; Humans; Male; Middle Aged; Nifedipine; Phenytoin

1989
[Gingival hyperplasia induced by nifedipine. Report of two cases].
    Odontostomatologike proodos, 1989, Volume: 43, Issue:4

    Topics: Aged; Female; Gingival Hyperplasia; Humans; Male; Nifedipine

1989
Nifedipine-induced gingival hyperplasia.
    Journal (Canadian Dental Association), 1989, Volume: 55, Issue:5

    Topics: Coronary Disease; Gingival Hyperplasia; Humans; Male; Middle Aged; Nifedipine

1989
[Gingival hyperplasia associated with nifedipine].
    Revista clinica espanola, 1989, Volume: 184, Issue:6

    Topics: Adult; Gingival Hyperplasia; Humans; Male; Nifedipine; Phenytoin

1989
Gingival hyperplasia following nifedipine therapy.
    Clinical and experimental dermatology, 1989, Volume: 14, Issue:1

    Topics: Adult; Aged; Female; Gingival Hyperplasia; Humans; Male; Middle Aged; Nifedipine

1989
Cyclosporin, nifedipine, and gingival hyperplasia.
    Lancet (London, England), 1987, Sep-26, Volume: 2, Issue:8561

    Topics: Cyclosporins; Female; Gingival Hyperplasia; Humans; Nifedipine; Postoperative Complications

1987
[Calcium antagonists and gingival hyperplasia].
    Attualita dentale, 1988, Jan-17, Volume: 4, Issue:1

    Topics: Collagen; Dental Scaling; Epidermolysis Bullosa; Gingival Hyperplasia; Humans; Male; Mastication; Mi

1988
Nifedipine (Procardia) and gingival hyperplasia: a new diagnostic concern for practitioners.
    Bulletin. Ninth District Dental Society of the State of New York, 1986, Volume: 70, Issue:2

    Topics: Aged; Gingival Hyperplasia; Humans; Male; Middle Aged; Nifedipine

1986
The CO2 laser in the excision of gingival hyperplasia caused by nifedipine.
    Journal of clinical periodontology, 1988, Volume: 15, Issue:10

    Topics: Adult; Carbon Dioxide; Gingival Hyperplasia; Humans; Laser Therapy; Male; Nifedipine

1988
[Gingival hyperplasia due to diphenylhydantoin, cyclosporin A and nifedipine. A histopathological comparison].
    Minerva stomatologica, 1988, Volume: 37, Issue:3

    Topics: Biopsy; Connective Tissue; Cyclosporins; Gingiva; Gingival Hyperplasia; Humans; Nifedipine; Phenytoi

1988
[Nifedipine-induced gingival hyperplasia].
    Duodecim; laaketieteellinen aikakauskirja, 1988, Volume: 104, Issue:14

    Topics: Gingival Hyperplasia; Humans; Male; Middle Aged; Nifedipine

1988
Nifedipine induced gingival hyperplasia.
    The Journal of the Association of Physicians of India, 1988, Volume: 36, Issue:3

    Topics: Diabetes Mellitus, Type 2; Female; Gingival Hyperplasia; Humans; Middle Aged; Myocardial Infarction;

1988
Gingival hyperplasia in dogs induced by oxodipine, a calcium channel blocking agent.
    Toxicologic pathology, 1988, Volume: 16, Issue:3

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Calcium Channel Blockers; Dihydropyridines; Dog

1988
Gingival hyperplasia caused by nifedipine.
    Proceedings of the Finnish Dental Society. Suomen Hammaslaakariseuran toimituksia, 1988, Volume: 84, Issue:5-6

    Topics: Gingival Hemorrhage; Gingival Hyperplasia; Humans; Male; Middle Aged; Nifedipine

1988
Gingival hyperplasia: an intra-oral side effect of phenytoin, nifedipine and cyclosporine therapies.
    Singapore medical journal, 1988, Volume: 29, Issue:5

    Topics: Adult; Cyclosporins; Female; Gingival Hyperplasia; Humans; Nifedipine; Phenytoin

1988
[Ifedipine induced gingival hyperplasia. Review and clinical cases].
    Revista de actualidad estomatologica espanola, 1988, Volume: 48, Issue:379

    Topics: Angina Pectoris; Female; Gingival Hyperplasia; Gingivectomy; Humans; Male; Middle Aged; Nifedipine

1988
Gingival hyperplasia associated with nifedipine.
    British dental journal, 1986, Jun-21, Volume: 160, Issue:12

    Topics: Gingival Hyperplasia; Humans; Male; Middle Aged; Nifedipine

1986
[Essential and iatrogenic gingival hyperplasia. Its morphology and significance].
    Revue de stomatologie et de chirurgie maxillo-faciale, 1986, Volume: 87, Issue:5

    Topics: Adolescent; Adult; Chronic Disease; Cyclosporins; Female; Gingiva; Gingival Hyperplasia; Gingivectom

1986
Drug-induced gingival hyperplasia: phenytoin, cyclosporine, and nifedipine.
    Journal of the American Dental Association (1939), 1987, Volume: 114, Issue:1

    Topics: Adult; Child; Cyclosporins; Female; Gingival Hyperplasia; Humans; Male; Nifedipine; Phenytoin

1987
[Gingiva hyperplasia caused by nifedipine therapy].
    Tandlaegebladet, 1986, Volume: 90, Issue:15

    Topics: Gingival Hyperplasia; Humans; Male; Middle Aged; Nifedipine

1986
Gingival overgrowth in a patient treated with nifedipine (Procardia).
    Periodontal case reports : a publication of the Northeastern Society of Periodontists, 1986, Volume: 8, Issue:2

    Topics: Adult; Gingival Hyperplasia; Humans; Male; Nifedipine

1986
Gingival hyperplasia caused by nifedipine. Histopathologic findings.
    Journal of periodontology, 1987, Volume: 58, Issue:9

    Topics: Adult; Aged; Epithelium; Female; Gingiva; Gingival Hyperplasia; Humans; Keratosis; Male; Middle Aged

1987
Drugs in dentistry. Medications for gingival hyperplasia.
    Dental management, 1987, Volume: 27, Issue:11

    Topics: Cyclosporins; Gingival Hyperplasia; Humans; Nifedipine; Phenytoin

1987
[Gingival hyperplasia from nifedipine].
    Dental Cadmos, 1987, Nov-30, Volume: 55, Issue:18

    Topics: Aged; Gingival Hyperplasia; Gingivectomy; Humans; Male; Middle Aged; Nifedipine

1987
[Gingival hyperplasia induced by nifedipine. Effect of nifedipine and EGF on cell proliferation in human gingival fibroblasts].
    Nihon Shishubyo Gakkai kaishi, 1986, Volume: 28, Issue:1

    Topics: Cell Division; DNA; Epidermal Growth Factor; Fibroblasts; Gingiva; Gingival Hyperplasia; Humans; Nif

1986
[Nifedipine-induced gingival hyperplasia].
    Medicina clinica, 1987, Oct-24, Volume: 89, Issue:13

    Topics: Adult; Gingival Hyperplasia; Humans; Male; Nifedipine

1987
[Gingival hyperplasia caused by nifedipine].
    Giornale italiano di cardiologia, 1986, Volume: 16, Issue:4

    Topics: Aged; Gingival Hyperplasia; Humans; Male; Nifedipine

1986
Nifedipine-induced gingival hyperplasia. A histochemical and ultrastructural study.
    Journal of periodontology, 1985, Volume: 56, Issue:4

    Topics: Acid Phosphatase; Adult; Aged; Alcian Blue; Female; Fibroblasts; Gingiva; Gingival Hyperplasia; Huma

1985
[Clinical and histopathological observations of the gingiva in heart patients treated with nifedipine--a report of 3 cases].
    Nihon Shishubyo Gakkai kaishi, 1985, Volume: 27, Issue:1

    Topics: Gingiva; Gingival Hyperplasia; Heart Diseases; Humans; Male; Middle Aged; Nifedipine

1985
Gingival hyperplasia induced by nifedipine, an arterial vasodilating drug.
    Oral surgery, oral medicine, and oral pathology, 1985, Volume: 60, Issue:1

    Topics: Adult; Female; Gingiva; Gingival Hyperplasia; Humans; Nifedipine

1985