nifedipine has been researched along with Flushing in 8 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Flushing: A transient reddening of the face that may be due to fever, certain drugs, exertion, or stress.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nicardipine and nifedipine are structurally similar dihydropyridine calcium channel blockers with demonstrated efficacy in the treatment of stable angina pectoris." | 9.06 | Randomized double-blind comparison of side effects of nicardipine and nifedipine in angina pectoris. The Nicardipine Investigators Group. ( DeWood, MA; Wolbach, RA, 1990) |
| "Nifedipine, 30 mg/day for 4 weeks, was compared to placebo in a double-blind, randomized, crossover study, as an additional drug added to the usual treatment of 14 patients with bronchial asthma." | 9.06 | Nifedipine treatment of patients with bronchial asthma. ( Dascalopoulou, E; Maniki, E; Patakas, D; Tsara, V, 1987) |
| "Flushing is one of the most common vasodilation-related adverse effects associated with Ca(2+) channel antagonist treatment." | 5.32 | Ovariectomy aggravates nifedipine-induced flushing of tail skin in mice. ( Kai, H; Kai, M; Kataoka, Y; Okimoto, K; Tominaga, K; Yamauchi, A, 2003) |
| "In a multicentre crossover study of 97 patients with mild hypertension, the incidence and severity of adverse effects were observed during the first 14 days of treatment with amlodipine, nifedipine retard or placebo." | 5.07 | Early side-effects of antihypertensive therapy: comparison of amlodipine and nifedipine retard. ( Bremner, AD; Fell, PJ; Hosie, J; James, IG; Saul, PA; Taylor, SH, 1993) |
| "Nicardipine and nifedipine are structurally similar dihydropyridine calcium channel blockers with demonstrated efficacy in the treatment of stable angina pectoris." | 5.06 | Randomized double-blind comparison of side effects of nicardipine and nifedipine in angina pectoris. The Nicardipine Investigators Group. ( DeWood, MA; Wolbach, RA, 1990) |
| "Nifedipine, 30 mg/day for 4 weeks, was compared to placebo in a double-blind, randomized, crossover study, as an additional drug added to the usual treatment of 14 patients with bronchial asthma." | 5.06 | Nifedipine treatment of patients with bronchial asthma. ( Dascalopoulou, E; Maniki, E; Patakas, D; Tsara, V, 1987) |
| " Compared with placebo, barnidipine lowered blood pressure, with a trend toward a dose-response relationship over the dose range 10-30 mg." | 2.68 | Barnidipine, a novel calcium antagonist for once-daily treatment of hypertension: a multicenter, double-blind, placebo-controlled, dose-ranging study. Dutch Barnidipine Multicenter Study Group. ( Hart, W; Holwerda, NJ, 1997) |
| "Amlodipine treatment was associated with a slightly higher incidence of side effects compared with placebo, but most of this difference was the result of edema, which was usually well tolerated." | 2.66 | The safety of amlodipine. ( Osterloh, I, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kai, M | 1 |
| Tominaga, K | 1 |
| Okimoto, K | 1 |
| Yamauchi, A | 1 |
| Kai, H | 1 |
| Kataoka, Y | 1 |
| Bremner, AD | 1 |
| Fell, PJ | 1 |
| Hosie, J | 1 |
| James, IG | 1 |
| Saul, PA | 1 |
| Taylor, SH | 1 |
| Ariad, S | 1 |
| Hechtlinger, V | 1 |
| Hart, W | 1 |
| Holwerda, NJ | 1 |
| DeWood, MA | 1 |
| Wolbach, RA | 1 |
| Hannedouche, T | 1 |
| Fillastre, JP | 1 |
| Mimran, A | 1 |
| de Tréglodé, D | 1 |
| Schardt, F | 1 |
| Rosenthal, T | 1 |
| Grossman, E | 1 |
| Rocco, S | 1 |
| Osterloh, I | 1 |
| Patakas, D | 1 |
| Maniki, E | 1 |
| Tsara, V | 1 |
| Dascalopoulou, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Fixed-Dose Combination of Perindopril/Amlodipine (Amlessa®) and Fixed-Dose Combination of Perindopril/Indapamide /Amlodipine (Co-Amlessa®) - Contribution to Management in Newly Diagnosed and Uncontrolled Hypertensive Patients[NCT03738761] | Phase 4 | 471 participants (Actual) | Interventional | 2018-02-13 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 trials available for nifedipine and Flushing
| Article | Year |
|---|---|
Early side-effects of antihypertensive therapy: comparison of amlodipine and nifedipine retard.
Topics: Adult; Aged; Amlodipine; Delayed-Action Preparations; Dizziness; Double-Blind Method; Edema; Female; | 1993 |
Barnidipine, a novel calcium antagonist for once-daily treatment of hypertension: a multicenter, double-blind, placebo-controlled, dose-ranging study. Dutch Barnidipine Multicenter Study Group.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Edema; Female; Flushing; He | 1997 |
Randomized double-blind comparison of side effects of nicardipine and nifedipine in angina pectoris. The Nicardipine Investigators Group.
Topics: Adult; Angina Pectoris; Dizziness; Double-Blind Method; Edema; Flushing; Foot Diseases; Headache; Hu | 1990 |
Ketanserin versus nifedipine in the treatment of essential hypertension in patients over 50 years old: an international multicenter study.
Topics: Blood Pressure; Body Weight; Clinical Trials as Topic; Female; Flushing; Heart Rate; Humans; Hyperte | 1987 |
The safety of amlodipine.
Topics: Adrenergic beta-Antagonists; Aged; Amlodipine; Calcium Channel Blockers; Clinical Trials as Topic; D | 1989 |
Nifedipine treatment of patients with bronchial asthma.
Topics: Adult; Aged; Albuterol; Asthma; Blood Pressure; Circadian Rhythm; Clinical Trials as Topic; Double-B | 1987 |
2 other studies available for nifedipine and Flushing
| Article | Year |
|---|---|
Ovariectomy aggravates nifedipine-induced flushing of tail skin in mice.
Topics: Analysis of Variance; Animals; Dose-Response Relationship, Drug; Estradiol; Female; Flushing; Mice; | 2003 |
Bezafibrate-induced neutropenia.
Topics: Bezafibrate; Dyspnea; Female; Flushing; Humans; Hyperlipidemias; Hypertension; Leukocyte Count; Midd | 1993 |