Page last updated: 2024-11-01

nifedipine and Fetal Membranes, Premature Rupture

nifedipine has been researched along with Fetal Membranes, Premature Rupture in 13 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Fetal Membranes, Premature Rupture: Spontaneous tearing of the membranes surrounding the FETUS any time before the onset of OBSTETRIC LABOR. Preterm PROM is membrane rupture before 37 weeks of GESTATION.

Research Excerpts

ExcerptRelevanceReference
"Risk factors for preterm labor commonly observed in the study group were urinary tract infection (60."5.39Pregnancy outcomes and successful rate of nifedipine therapeutic protocol implementation in a hospital of San Juan. ( Catalano, LN; Negron, I; Rivera Rosa, E; Vázquez Guzmán, M; Villar Diaz, M, 2013)
" The aim of this trial was to study the effect of prolonged tocolysis with nifedipine versus placebo in women with PPROM on perinatal outcome and prolongation of pregnancy."5.22Nifedipine versus placebo in the treatment of preterm prelabor rupture of membranes: a randomized controlled trial: Assessment of perinatal outcome by use of tocolysis in early labor-APOSTEL IV trial. ( Bax, CJ; Bloemenkamp, KW; de Lange, TS; Franx, A; Kok, M; Mol, BW; Naaktgeboren, CA; Nijman, TA; Oude Rengerink, K; Oudijk, MA; Scheepers, HC; van Eyck, J; van Vliet, EO; Woiski, M, 2016)
"To analyse the expression of 15 genes encoding receptors and enzymes associated with the molecular mechanism of the tocolytic drugs atosiban (oxytocin receptor antagonist), nifedipine (calcium channel blocker) and celecoxib (selective cyclo-oxygenase-2 inhibitor) in preterm labor patients with premature rupture of fetal membranes in relation to symptoms of intrauterine infection and preterm labor risk factors."3.78Expression of selected genes in preterm premature rupture of fetal membranes. ( Chyczewski, L; Kowalczuk, O; Kuć, P; Laudański, P; Laudański, T, 2012)
"Risk factors for preterm labor commonly observed in the study group were urinary tract infection (60."1.39Pregnancy outcomes and successful rate of nifedipine therapeutic protocol implementation in a hospital of San Juan. ( Catalano, LN; Negron, I; Rivera Rosa, E; Vázquez Guzmán, M; Villar Diaz, M, 2013)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.69)18.2507
2000's2 (15.38)29.6817
2010's8 (61.54)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Lorthe, E1
Kayem, G1
Emeruwa, UN1
Krenitsky, NM1
Sheen, JJ1
Kutuk, MS1
Ozgun, MT1
Uludag, S1
Dolanbay, M1
Yildirim, A1
Catalano, LN1
Villar Diaz, M1
Vázquez Guzmán, M1
Negron, I1
Rivera Rosa, E1
Mackeen, AD2
Seibel-Seamon, J2
Muhammad, J1
Baxter, JK2
Berghella, V2
Khoo, F1
Mathur, M1
van Vliet, E1
Seinen, L1
Roos, C1
Schuit, E1
Scheepers, H1
Bloemenkamp, K1
Duvekot, JJ1
van Eyck, J2
Kok, JH1
Lotgering, FK1
van Baar, A1
van Wassenaer-Leemhuis, AG1
Franssen, MT1
Porath, MM1
van der Post, J1
Franx, A2
Mol, B1
Oudijk, MA2
Nijman, TA1
van Vliet, EO1
Naaktgeboren, CA1
Oude Rengerink, K1
de Lange, TS1
Bax, CJ1
Bloemenkamp, KW1
Kok, M1
Scheepers, HC1
Woiski, M1
Mol, BW1
Grimes-Dennis, J1
Kuć, P1
Laudański, P1
Kowalczuk, O1
Chyczewski, L1
Laudański, T1
Loi, K1
Tan, KT1
Nassar, AH1
Ghazeeri, G1
Usta, IM1
Papatsonis, DN1
Van Geijn, HP1
Adèr, HJ1
Lange, FM1
Bleker, OP1
Dekker, GA1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Tocolysis in the Management of Preterm Premature Rupture of Membranes Before 34 Weeks of Gestation: a Double-blinded Randomized Controlled Trial[NCT03976063]Phase 3850 participants (Anticipated)Interventional2019-10-07Recruiting
Nifedipine Compared to Atosiban for Treating Preterm Labor. A Randomized Controlled Trial.[NCT00599898]Phase 4145 participants (Actual)Interventional2008-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for nifedipine and Fetal Membranes, Premature Rupture

ArticleYear
Advances in Management for Preterm Fetuses at Risk of Delivery.
    Clinics in perinatology, 2020, Volume: 47, Issue:4

    Topics: Anti-Bacterial Agents; Anticonvulsants; Betamethasone; Dexamethasone; Female; Fetal Membranes, Prema

2020
Tocolytics for preterm premature rupture of membranes.
    The Cochrane database of systematic reviews, 2014, Feb-27, Issue:2

    Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Anti-Bacterial Agents; Female; Fetal Membranes, P

2014
Tocolytics for preterm premature rupture of membranes.
    The Cochrane database of systematic reviews, 2011, Oct-05, Issue:10

    Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Anti-Bacterial Agents; Female; Fetal Membranes, P

2011

Trials

4 trials available for nifedipine and Fetal Membranes, Premature Rupture

ArticleYear
Tocolysis in the management of preterm prelabor rupture of membranes at 22-33 weeks of gestation: study protocol for a multicenter, double-blind, randomized controlled trial comparing nifedipine with placebo (TOCOPROM).
    BMC pregnancy and childbirth, 2021, Sep-08, Volume: 21, Issue:1

    Topics: Administration, Oral; Double-Blind Method; Female; Fetal Membranes, Premature Rupture; Gestational A

2021
Maintenance tocolysis with nifedipine in threatened preterm labour: 2-year follow up of the offspring in the APOSTEL II trial.
    BJOG : an international journal of obstetrics and gynaecology, 2016, Volume: 123, Issue:7

    Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Fetal Membranes, Premature Rupture; Follow

2016
Nifedipine versus placebo in the treatment of preterm prelabor rupture of membranes: a randomized controlled trial: Assessment of perinatal outcome by use of tocolysis in early labor-APOSTEL IV trial.
    European journal of obstetrics, gynecology, and reproductive biology, 2016, Volume: 205

    Topics: Adult; Female; Fetal Membranes, Premature Rupture; Humans; Nifedipine; Obstetric Labor, Premature; P

2016
Nifedipine and ritodrine in the management of preterm labor: a randomized multicenter trial.
    Obstetrics and gynecology, 1997, Volume: 90, Issue:2

    Topics: Administration, Oral; Adult; Female; Fetal Membranes, Premature Rupture; Humans; Infusions, Intraven

1997

Other Studies

6 other studies available for nifedipine and Fetal Membranes, Premature Rupture

ArticleYear
Acute pulmonary failure due to pulmonary edema during tocolytic therapy with nifedipine.
    Archives of gynecology and obstetrics, 2013, Volume: 288, Issue:4

    Topics: Acute Disease; Adult; Female; Fetal Membranes, Premature Rupture; Humans; Nifedipine; Obstetric Labo

2013
Pregnancy outcomes and successful rate of nifedipine therapeutic protocol implementation in a hospital of San Juan.
    Boletin de la Asociacion Medica de Puerto Rico, 2013, Volume: 105, Issue:3

    Topics: Adolescent; Adult; Dexamethasone; Drug Administration Schedule; Drug Evaluation; Female; Fetal Membr

2013
Severe resistant maternal hypotension following tocolysis with nifedipine.
    BMJ case reports, 2014, Dec-16, Volume: 2014

    Topics: Adolescent; Cesarean Section; Female; Fetal Membranes, Premature Rupture; Fluid Therapy; Gestational

2014
Expression of selected genes in preterm premature rupture of fetal membranes.
    Acta obstetricia et gynecologica Scandinavica, 2012, Volume: 91, Issue:8

    Topics: Adult; Calcium Channel Blockers; Calcium Channels, L-Type; Celecoxib; Cyclooxygenase 2 Inhibitors; D

2012
Massive pre-placental and subchorionic haematoma.
    Singapore medical journal, 2006, Volume: 47, Issue:12

    Topics: 17 alpha-Hydroxyprogesterone Caproate; Adult; Female; Fetal Membranes, Premature Rupture; Hematoma;

2006
Nifedipine-associated pulmonary complications in pregnancy.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2007, Volume: 97, Issue:2

    Topics: Adrenal Cortex Hormones; Female; Fetal Membranes, Premature Rupture; Fluid Therapy; Humans; Nifedipi

2007