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nifedipine and Esophageal Diseases

nifedipine has been researched along with Esophageal Diseases in 15 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Esophageal Diseases: Pathological processes in the ESOPHAGUS.

Research Excerpts

ExcerptRelevanceReference
"We have used a placebo controlled trial to investigate the effect of long-term administration of nifedipine in the prevention of symptomatic episodes of oesophageal spasm."9.06Trial of nifedipine for prevention of oesophageal spasm. ( Davies, HA; Henderson, AH; Lewis, MJ; Rhodes, J, 1987)
"Although nifedipine therapy resulted in substantial relief of dysphagia in six patients with diffuse esophageal spasm, significant side effects, particularly in young working subjects, precluded prolonged use."7.67Nifedipine therapy for diffuse esophageal spasm. ( Morse, J; Thomas, E; Willis, M; Witt, P, 1986)
"Nifedipine, however, was no better than placebo in the relief of daily chest pain frequency, severity, or index (frequency X severity) as assessed by patient diaries."6.66Oral nifedipine in the treatment of noncardiac chest pain in patients with the nutcracker esophagus. ( Bradley, LA; Castell, DO; Dalton, CB; Richter, JE, 1987)
"We have used a placebo controlled trial to investigate the effect of long-term administration of nifedipine in the prevention of symptomatic episodes of oesophageal spasm."5.06Trial of nifedipine for prevention of oesophageal spasm. ( Davies, HA; Henderson, AH; Lewis, MJ; Rhodes, J, 1987)
"Although nifedipine therapy resulted in substantial relief of dysphagia in six patients with diffuse esophageal spasm, significant side effects, particularly in young working subjects, precluded prolonged use."3.67Nifedipine therapy for diffuse esophageal spasm. ( Morse, J; Thomas, E; Willis, M; Witt, P, 1986)
"Nifedipine, however, was no better than placebo in the relief of daily chest pain frequency, severity, or index (frequency X severity) as assessed by patient diaries."2.66Oral nifedipine in the treatment of noncardiac chest pain in patients with the nutcracker esophagus. ( Bradley, LA; Castell, DO; Dalton, CB; Richter, JE, 1987)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199014 (93.33)18.7374
1990's1 (6.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nasrallah, SM2
Traube, M1
McCallum, RW1
Cargill, G1
Theodore, C1
Paolaggi, JA1
Davies, HA2
Lewis, M1
Rhodes, J2
Henderson, A1
Baunack, AR1
Weihrauch, TR1
Geller, LI1
Petrenko, VF1
Janssens, J1
Vantrappen, G1
Ghillebert, G1
Pressly, TA1
Winkler, A1
Alpert, MA1
Jackson, RW1
Mukerji, V1
Benge, JM1
Sharp, GC1
Jean, F1
Aubert, A1
Bloch, F1
Petite, JP1
Priollet, P1
Fiessinger, JN1
Husson, JM1
Billaud, E1
Lewis, MJ1
Henderson, AH1
Richter, JE2
Dalton, CB2
Bradley, LA1
Castell, DO2
Thomas, E1
Witt, P1
Willis, M1
Morse, J1
Tommaso, CL1
Singleton, RT1
Backhaus, EA1
Buice, RG1

Reviews

1 review available for nifedipine and Esophageal Diseases

ArticleYear
Calcium-channel blockers and the gastrointestinal tract. American College of Gastroenterology's Committee on FDA related matters.
    The American journal of gastroenterology, 1984, Volume: 79, Issue:11

    Topics: Animals; Calcium Channel Blockers; Digestive System; Diltiazem; Esophageal Achalasia; Esophageal Dis

1984

Trials

5 trials available for nifedipine and Esophageal Diseases

ArticleYear
Effects of diltiazem versus nifedipine on lower esophageal sphincter pressure in patients with progressive systemic sclerosis.
    Arthritis and rheumatism, 1986, Volume: 29, Issue:8

    Topics: Adult; Aged; Benzazepines; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Esophageal Dise

1986
Trial of nifedipine for prevention of oesophageal spasm.
    Digestion, 1987, Volume: 36, Issue:2

    Topics: Adult; Double-Blind Method; Drug Evaluation; Esophageal Diseases; Female; Humans; Male; Middle Aged;

1987
Oral nifedipine in the treatment of noncardiac chest pain in patients with the nutcracker esophagus.
    Gastroenterology, 1987, Volume: 93, Issue:1

    Topics: Administration, Oral; Adult; Aged; Chest Pain; Double-Blind Method; Esophageal Diseases; Female; Fol

1987
Primary esophageal motor disorders: clinical response to nifedipine.
    Southern medical journal, 1985, Volume: 78, Issue:3

    Topics: Adult; Aged; Esophageal Achalasia; Esophageal Diseases; Esophagogastric Junction; Female; Humans; Ma

1985
Nifedipine: a potent inhibitor of contractions in the body of the human esophagus. Studies in healthy volunteers and patients with the nutcracker esophagus.
    Gastroenterology, 1985, Volume: 89, Issue:3

    Topics: Adult; Dose-Response Relationship, Drug; Double-Blind Method; Drug Evaluation; Esophageal Diseases;

1985

Other Studies

9 other studies available for nifedipine and Esophageal Diseases

ArticleYear
Nifedipine in the treatment of diffuse oesophageal spasm.
    Lancet (London, England), 1982, Dec-04, Volume: 2, Issue:8310

    Topics: Esophageal Diseases; Humans; Male; Middle Aged; Nifedipine; Pyridines; Spasm

1982
Drugs can help oesophageal motility disorders.
    Drug and therapeutics bulletin, 1984, Mar-09, Volume: 22, Issue:5

    Topics: Esophageal Achalasia; Esophageal Diseases; Humans; Hydralazine; Nifedipine; Nitrates

1984
Nifedipine for relief of esophageal chest pain?
    The New England journal of medicine, 1982, 07-15, Volume: 307, Issue:3

    Topics: Esophageal Diseases; Humans; Nifedipine; Pain; Pyridines; Thorax

1982
Nifedipine for relief of esophageal chest pain?
    The New England journal of medicine, 1982, Nov-11, Volume: 307, Issue:20

    Topics: Esophageal Diseases; Humans; Nifedipine; Pain; Pyridines; Spasm; Thorax

1982
Clinical efficacy of nifedipine and other calcium antagonists in patients with primary esophageal motor dysfunctions.
    Arzneimittel-Forschung, 1991, Volume: 41, Issue:6

    Topics: Adolescent; Adult; Aged; Calcium Channel Blockers; Child; Child, Preschool; Esophageal Diseases; Fem

1991
[Disorders of esophageal motility as a cause of retrosternal pain].
    Terapevticheskii arkhiv, 1986, Volume: 58, Issue:2

    Topics: Adult; Diagnosis, Differential; Esophageal Diseases; Esophagitis, Peptic; Female; Gastrointestinal M

1986
Oral nifedipine in the treatment of noncardiac chest pain.
    Gastroenterology, 1988, Volume: 94, Issue:2

    Topics: Administration, Oral; Chest Pain; Esophageal Diseases; Humans; Nifedipine

1988
Value and limitations of calcium channel blockade in the treatment of pulmonary hypertension associated with CREST--case reports.
    Angiology, 1988, Volume: 39, Issue:4

    Topics: Adult; Calcinosis; Diltiazem; Esophageal Diseases; Female; Humans; Hypertension, Pulmonary; Male; Mi

1988
Nifedipine therapy for diffuse esophageal spasm.
    Southern medical journal, 1986, Volume: 79, Issue:7

    Topics: Dizziness; Drug Evaluation; Esophageal Diseases; Female; Headache; Humans; Male; Manometry; Nifedipi

1986