nifedipine and Endotoxemia studies

nifedipine and Endotoxemia

nifedipine has been researched along with Endotoxemia in 2 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Endotoxemia: A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.

Research Excerpts

Excerpt	Relevance	Reference
"Pretreatment with nifedipine not only significantly blocked the enhancing effects of DOB on LPS-induced elevation in cytosolic Ca(2+) concentration and CaMKII phosphorylation in cardiomyocytes, but also partly reversed the effects of DOB on caspase-9 and caspase-3/7 activities in LPS-treated cardiomyocytes."	1.42	β₁-adrenoceptor stimulation promotes LPS-induced cardiomyocyte apoptosis through activating PKA and enhancing CaMKII and IκBα phosphorylation. ( Li, H; Lu, D; Lv, X; Wang, H; Wang, Y; Yang, D; Yu, X, 2015)

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

1 (50.00)

18.2507

2000's

0 (0.00)

29.6817

2010's

1 (50.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Wang, Y	2
Yang, D	1
Yu, X	1
Li, H	1
Lv, X	1
Lu, D	1
Wang, H	1
Wu, CC	1
Wang, JH	1
Chiao, CW	1
Yen, MH	1

Studies

Wang, Y

Yang, D

Yu, X

Li, H

Lv, X

Lu, D

Wang, H

Wu, CC

Wang, JH

Chiao, CW

Yen, MH

Other Studies

2 other studies available for nifedipine and Endotoxemia

Article	Year
β₁-adrenoceptor stimulation promotes LPS-induced cardiomyocyte apoptosis through activating PKA and enhancing CaMKII and IκBα phosphorylation. Critical care (London, England), 2015, Mar-09, Volume: 19 Topics: Adrenergic beta-1 Receptor Agonists; Animals; Apoptosis; Calcium Channel Blockers; Calcium-Calmoduli	2015
Comparison between effects of dantrolene and nifedipine on lipopolysaccharide-induced endotoxemia in the anesthetized rats. The Chinese journal of physiology, 1999, Dec-31, Volume: 42, Issue:4 Topics: Anesthesia; Animals; Blood Glucose; Blood Pressure; Body Temperature; Dantrolene; Endotoxemia; Lipop	1999

Article

Year

β₁-adrenoceptor stimulation promotes LPS-induced cardiomyocyte apoptosis through activating PKA and enhancing CaMKII and IκBα phosphorylation.

Critical care (London, England), 2015, Mar-09, Volume: 19

Topics: Adrenergic beta-1 Receptor Agonists; Animals; Apoptosis; Calcium Channel Blockers; Calcium-Calmoduli

2015

Comparison between effects of dantrolene and nifedipine on lipopolysaccharide-induced endotoxemia in the anesthetized rats.

The Chinese journal of physiology, 1999, Dec-31, Volume: 42, Issue:4

Topics: Anesthesia; Animals; Blood Glucose; Blood Pressure; Body Temperature; Dantrolene; Endotoxemia; Lipop

1999