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nifedipine and Diabetes Mellitus

nifedipine has been researched along with Diabetes Mellitus in 24 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.

Research Excerpts

ExcerptRelevanceReference
"To investigate the impact of treatment on cardiovascular mortality and morbidity, we assessed outcomes in patients with hypertension and diabetes who received co-amilozide or nifedipine in the International Nifedipine GITS Study: Intervention as a Goal in Hypertension."9.10Outcomes with nifedipine GITS or Co-amilozide in hypertensive diabetics and nondiabetics in Intervention as a Goal in Hypertension (INSIGHT). ( Brown, M; Castaigne, A; de Leeuw, P; Mancia, G; Palmer, CR; Rosenthal, T; Ruilope, LM; Wagener, G, 2003)
"This study aimed to evaluate the efficacy of nifedipine controlled-release tablets combined with sacubitril valsartan in diabetic nephropathy (DN) patients with hypertension."8.31Therapeutic improvements of nifedipine controlled-release tablets combined with sacubitril valsartan on patients with diabetic nephropathy complicated with hypertension. ( Hu, L; Liu, G; Wei, Y, 2023)
"To investigate the impact of treatment on cardiovascular mortality and morbidity, we assessed outcomes in patients with hypertension and diabetes who received co-amilozide or nifedipine in the International Nifedipine GITS Study: Intervention as a Goal in Hypertension."5.10Outcomes with nifedipine GITS or Co-amilozide in hypertensive diabetics and nondiabetics in Intervention as a Goal in Hypertension (INSIGHT). ( Brown, M; Castaigne, A; de Leeuw, P; Mancia, G; Palmer, CR; Rosenthal, T; Ruilope, LM; Wagener, G, 2003)
"The effects of nisoldipine and slow release nifedipine on mild to moderate hypertension and glycaemic control were studied in 28 diabetic hypertensives, all except one of whom were non-insulin dependent."5.07Nifedipine and nisoldipine in hypertensive diabetics. ( Clarke, CW; Kubik, MM, 1991)
"This study aimed to evaluate the efficacy of nifedipine controlled-release tablets combined with sacubitril valsartan in diabetic nephropathy (DN) patients with hypertension."4.31Therapeutic improvements of nifedipine controlled-release tablets combined with sacubitril valsartan on patients with diabetic nephropathy complicated with hypertension. ( Hu, L; Liu, G; Wei, Y, 2023)
"Atenolol treatment significantly increased triglyceride levels and decreased the HDL-cholesterol levels after 9 months in both groups."2.68Comparative effects of atenolol versus nifedipine on serum lipids and other biochemical parameters in diabetic and non-diabetic hypertensive subjects. ( Goyal, RK; Satia, MC; Shukla, ML, 1995)
" In fact, there is a low possibility to derange the balance between insulin and glucagon secretion after acute and chronic administration of CEBs at conventional dosages."2.37[Effects of calcium antagonist drugs on glucide metabolism]. ( Gusmini, G; Lombardi, C; Rangoni, G; Spedini, C, 1988)
"Does nifedipine treatment slow down the progression of coronary calcification in diabetic patients? If the answer is yes, is this beneficial effect of nifedipine superior to that of other DHPs with equihypotensive properties? Does nifedipine treatment decrease expression levels of AGEs and RAGE in diabetic atherosclerosis? Is the unique effect of nifedipine on vascular calcification correlated with its AGE or RAGE-suppressing properties? These prospective studies will provide further valuable information whether nifedipine could prevent vascular calcification in diabetic atherosclerosis by blockade the AGE-RAGE signaling in vascular wall cells."1.34Prevention of diabetic vascular calcification by nifedipine, a dihydropyridine-based calcium channel blocker. ( Matsui, T; Nakamura, K; Yamagishi, S, 2007)
"Nifedipine was the most frequently prescribed antihypertensive (44."1.32Inadequate control of blood pressure in Nigerians with diabetes. ( Okoro, EO; Oyejola, BA, 2004)
" When used in standard recommended oral dosage nifedipine has no significant effect on glucose tolerance."1.26Effect of nifedipine on glucose tolerance and insulin secretion in diabetic and non-diabetic patients. ( Donnelly, T; Harrower, AD, 1980)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199011 (45.83)18.7374
1990's7 (29.17)18.2507
2000's4 (16.67)29.6817
2010's0 (0.00)24.3611
2020's2 (8.33)2.80

Authors

AuthorsStudies
Wei, Y1
Hu, L1
Liu, G1
West, HL1
Corbin, KL1
D'Angelo, CV1
Donovan, LM1
Jahan, I1
Gu, G1
Nunemaker, CS1
Mancia, G1
Brown, M1
Castaigne, A1
de Leeuw, P1
Palmer, CR1
Rosenthal, T1
Wagener, G1
Ruilope, LM1
Okoro, EO1
Oyejola, BA1
Yoshida, D1
Higashiura, K1
Shimamoto, K1
Yamagishi, S1
Matsui, T1
Nakamura, K1
Trost, BN1
Weidmann, P1
Altura, BM1
Altura, BT1
Bhatnagar, SK1
Amin, MM1
Al-Yusuf, AR1
Abadie, E1
Gauville, C1
Brisson, C1
Donnelly, T1
Harrower, AD1
Giugliano, D1
Torella, R1
Cacciapuoti, F1
Gentile, S1
Verza, M1
Varricchio, M1
Cicco, G1
Pirrelli, A1
Satia, MC1
Shukla, ML1
Goyal, RK1
Haller, H1
Petralito, A1
Lunetta, M1
Liuzzo, A1
Fiore, CE1
Mangiafico, RA1
Gill, J1
Fonseca, V1
Dandona, P1
Jeremy, JY1
Preobrazhenskiĭ, DV1
Fomichev, VI1
Afanas'ev, AIa1
Ferder, L1
Daccordi, H1
Martello, M1
Panzalis, M1
Inserra, F1
Clarke, CW1
Kubik, MM1
Gusmini, G1
Lombardi, C1
Rangoni, G1
Spedini, C1
Benaim, ME1
Macdonald, G1
Kendall, MJ1
Horton, RC1
Chellingsworth, MC1

Reviews

7 reviews available for nifedipine and Diabetes Mellitus

ArticleYear
[Treatment of hypertensive patients with impaired glucose tolerance (IGT)].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 2

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive

2005
Effects of nitrendipine and other calcium antagonists on glucose metabolism in man.
    Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 7

    Topics: Blood Glucose; Calcium Channel Blockers; Diabetes Mellitus; Glucose; Glucose Tolerance Test; Glycate

1984
Microcirculatory actions and uses of naturally-occurring (magnesium) and novel synthetic calcium channel blockers.
    Microcirculation, endothelium, and lymphatics, 1984, Volume: 1, Issue:2

    Topics: Anesthesia; Animals; Arterioles; Blood Pressure; Calcium; Calcium Channel Blockers; Cell Membrane Pe

1984
Endothelial function. General considerations.
    Drugs, 1997, Volume: 53 Suppl 1

    Topics: Animals; Arteriosclerosis; Calcium Channel Blockers; Capillary Permeability; Diabetes Mellitus; Endo

1997
[Effects of calcium antagonists on carbohydrate and lipid metabolism].
    Kardiologiia, 1992, Volume: 32, Issue:4

    Topics: Animals; Calcium Channel Blockers; Carbohydrate Metabolism; Cholesterol; Coronary Disease; Diabetes

1992
[Effects of calcium antagonist drugs on glucide metabolism].
    Minerva medica, 1988, Volume: 79, Issue:10

    Topics: Animals; Calcium Channel Blockers; Diabetes Mellitus; Female; Glucagon; Glucose; Glucose Tolerance T

1988
Calcium antagonists and glycaemic control.
    Journal of clinical and hospital pharmacy, 1986, Volume: 11, Issue:3

    Topics: Blood Glucose; Calcium Channel Blockers; Diabetes Mellitus; Diltiazem; Glucose Tolerance Test; Human

1986

Trials

7 trials available for nifedipine and Diabetes Mellitus

ArticleYear
Outcomes with nifedipine GITS or Co-amilozide in hypertensive diabetics and nondiabetics in Intervention as a Goal in Hypertension (INSIGHT).
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:3

    Topics: Aged; Amiloride; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiovascular D

2003
Impairment of insulin secretion in man by nifedipine.
    European journal of clinical pharmacology, 1980, Volume: 18, Issue:5

    Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus; Female; Glucose Tolerance Test; Humans; Insulin; Insu

1980
Comparative effects of atenolol versus nifedipine on serum lipids and other biochemical parameters in diabetic and non-diabetic hypertensive subjects.
    Indian journal of physiology and pharmacology, 1995, Volume: 39, Issue:3

    Topics: Aged; Antihypertensive Agents; Atenolol; Blood Glucose; Blood Pressure; Blood Urea Nitrogen; Creatin

1995
Lisinopril and nifedipine administration inhibits the ex vivo uptake of [45Ca2+] by platelets from hypertensive diabetic patients.
    British journal of clinical pharmacology, 1992, Volume: 33, Issue:2

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Platelets; Bucladesine; Calcium; Diabet

1992
Angiotensin converting enzyme inhibitors versus calcium antagonists in the treatment of diabetic hypertensive patients.
    Hypertension (Dallas, Tex. : 1979), 1992, Volume: 19, Issue:2 Suppl

    Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Creatinine; Diab

1992
Nifedipine and nisoldipine in hypertensive diabetics.
    Journal of human hypertension, 1991, Volume: 5, Issue:6

    Topics: Adult; Aged; Blood Glucose; Blood Pressure; Diabetes Complications; Diabetes Mellitus; Humans; Hyper

1991
Effect of nifedipine on carbohydrate metabolism and serum lipoproteins in hypertensive patients with and without diabetes mellitus.
    European heart journal, 1987, Volume: 8 Suppl K

    Topics: Adult; Aged; Blood Pressure; Carbohydrate Metabolism; Diabetes Complications; Diabetes Mellitus; Fem

1987

Other Studies

10 other studies available for nifedipine and Diabetes Mellitus

ArticleYear
Therapeutic improvements of nifedipine controlled-release tablets combined with sacubitril valsartan on patients with diabetic nephropathy complicated with hypertension.
    International immunopharmacology, 2023, Volume: 123

    Topics: Biphenyl Compounds; Delayed-Action Preparations; Diabetes Mellitus; Diabetic Nephropathies; Drug Com

2023
Postnatal maturation of calcium signaling in islets of Langerhans from neonatal mice.
    Cell calcium, 2021, Volume: 94

    Topics: Aging; Animals; Animals, Newborn; Calcium; Calcium Channels, L-Type; Calcium Signaling; Diabetes Mel

2021
Inadequate control of blood pressure in Nigerians with diabetes.
    Ethnicity & disease, 2004,Winter, Volume: 14, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Care Facilities; Angiotensin-Converting Enzym

2004
Prevention of diabetic vascular calcification by nifedipine, a dihydropyridine-based calcium channel blocker.
    Medical hypotheses, 2007, Volume: 68, Issue:5

    Topics: Calcinosis; Calcium Channel Blockers; Diabetes Mellitus; Dihydropyridines; Humans; Models, Biologica

2007
Diabetogenic effects of nifedipine.
    British medical journal (Clinical research ed.), 1984, Jul-07, Volume: 289, Issue:6436

    Topics: Aged; Blood Glucose; Diabetes Mellitus; Humans; Hypertension; Male; Middle Aged; Nifedipine

1984
Diabetogenic effects of nifedipine.
    British medical journal (Clinical research ed.), 1984, Aug-18, Volume: 289, Issue:6442

    Topics: Diabetes Mellitus; Humans; Hyperglycemia; Nifedipine

1984
Nifedipine and endocrine status in diabetic patients.
    British journal of clinical pharmacology, 1984, Volume: 18, Issue:4

    Topics: Adult; Aged; Diabetes Mellitus; Growth Hormone; Humans; Middle Aged; Nifedipine

1984
Effect of nifedipine on glucose tolerance and insulin secretion in diabetic and non-diabetic patients.
    Current medical research and opinion, 1980, Volume: 6, Issue:10

    Topics: Adult; Aged; Angina Pectoris; Blood Glucose; Diabetes Mellitus; Female; Glucose Tolerance Test; Huma

1980
[Glyco-lipid changes in hypertensive diabetic patients undergoing treatment with nifedipine and captopril].
    Minerva medica, 1993, Volume: 84, Issue:3

    Topics: Adult; Blood Glucose; Captopril; Cholesterol; Diabetes Complications; Diabetes Mellitus; Follow-Up S

1993
[Influence of nifedipine on the curve of the glucose tolerance test in normal subjects and in subjects with altered carbohydrate metabolism].
    Bollettino della Societa italiana di cardiologia, 1979, Volume: 24, Issue:2

    Topics: Adult; Aged; Blood Glucose; Calcium; Carbohydrate Metabolism; Diabetes Mellitus; Glucose Tolerance T

1979