nifedipine has been researched along with Delayed Effects, Prenatal Exposure in 10 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The safety of use of the calcium channel blocker nifedipine in pregnancy as it affects child development has not been well evaluated." | 9.09 | Nifedipine administered in pregnancy: effect on the development of children at 18 months. ( Bortolus, R; Chatenoud, L; Parazzini, F; Ricci, E, 2000) |
| "The objective was to compare the fetal and maternal effects between parenteral hydralazine and sublingual nifedipine used like antihypertensive drugs in the management of severe preeclampsia." | 9.07 | [Management of severe pre-eclampsia/eclampsia. Comparison between nifedipine and hydralazine as antihypertensive agents]. ( Flores Padilla, LM; Walss Rodriguez, RJ, 1993) |
| "The safety of use of the calcium channel blocker nifedipine in pregnancy as it affects child development has not been well evaluated." | 5.09 | Nifedipine administered in pregnancy: effect on the development of children at 18 months. ( Bortolus, R; Chatenoud, L; Parazzini, F; Ricci, E, 2000) |
| "The objective was to compare the fetal and maternal effects between parenteral hydralazine and sublingual nifedipine used like antihypertensive drugs in the management of severe preeclampsia." | 5.07 | [Management of severe pre-eclampsia/eclampsia. Comparison between nifedipine and hydralazine as antihypertensive agents]. ( Flores Padilla, LM; Walss Rodriguez, RJ, 1993) |
| "Compelling evidence for the far-reaching role of oxytocin (OT) in social cognition and affiliative behaviors set the basis for examining the association between genetic variation in the OT receptor (OXTR) gene and risk for autism spectrum disorder (ASD)." | 3.91 | Cumulative Risk of the Oxytocin Receptor Gene Interacts with Prenatal Exposure to Oxytocin Receptor Antagonist to Predict Children's Social Communication Development. ( Feldstein, O; Friedlander, E; Harel-Gadassi, A; Israel, S; Laiba, E; Mankuta, D; Yaari, M; Yirmiya, N, 2019) |
| "Nine mothers were treated with labetalol and/or MgSO4 during pregnancy, three mothers with labetalol, MgSO4 and nifedipine, and 19 mothers with nifedipine only." | 3.79 | Maternal antihypertensive drugs may influence cerebral oxygen extraction in preterm infants during the first days after birth. ( Bos, AF; Kooi, EM; van den Berg, PP; Verhagen, EA, 2013) |
| " The uterus of adult progeny of rats treated with nifedipine during the late phase of pregnancy react in vitro to oxytocin less and the contractility of ones treated with higher dose (100 micrograms) disappears." | 3.69 | Effect of nifedipine treatment (imprinting) of rat feti and newborns on the responsiveness of adult rat's uterus. Extension of the imprinting theory. ( Csaba, G; Dobozy, O; Karabélyos, C; Kenéz, C, 1995) |
| "Women in acute preterm labor with cervical dilatation 1-6 cm were randomized to receive one of three first-line tocolytic drugs." | 2.77 | Effect of antenatal tocolysis on neonatal outcomes. ( Briery, CM; Keiser, SD; Klauser, CK; Kosek, MA; Martin, RW; Morrison, JC, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Friedlander, E | 1 |
| Yirmiya, N | 1 |
| Laiba, E | 1 |
| Harel-Gadassi, A | 1 |
| Yaari, M | 1 |
| Feldstein, O | 1 |
| Mankuta, D | 1 |
| Israel, S | 1 |
| Wu, C | 1 |
| Li, J | 1 |
| Bo, L | 1 |
| Gao, Q | 1 |
| Zhu, Z | 1 |
| Li, D | 1 |
| Li, S | 1 |
| Sun, M | 1 |
| Mao, C | 1 |
| Xu, Z | 1 |
| van Vliet, E | 1 |
| Seinen, L | 1 |
| Roos, C | 1 |
| Schuit, E | 1 |
| Scheepers, H | 1 |
| Bloemenkamp, K | 1 |
| Duvekot, JJ | 1 |
| van Eyck, J | 1 |
| Kok, JH | 1 |
| Lotgering, FK | 1 |
| van Baar, A | 1 |
| van Wassenaer-Leemhuis, AG | 1 |
| Franssen, MT | 1 |
| Porath, MM | 1 |
| van der Post, J | 1 |
| Franx, A | 1 |
| Mol, B | 1 |
| Oudijk, MA | 1 |
| Klauser, CK | 1 |
| Briery, CM | 1 |
| Keiser, SD | 1 |
| Martin, RW | 1 |
| Kosek, MA | 1 |
| Morrison, JC | 1 |
| Verhagen, EA | 1 |
| Kooi, EM | 1 |
| van den Berg, PP | 1 |
| Bos, AF | 1 |
| Houtzager, BA | 1 |
| Hogendoorn, SM | 1 |
| Papatsonis, DN | 1 |
| Samsom, JF | 1 |
| van Geijn, HP | 1 |
| Bleker, OP | 1 |
| van Wassenaer, AG | 1 |
| Csaba, G | 1 |
| Kenéz, C | 1 |
| Karabélyos, C | 1 |
| Dobozy, O | 1 |
| Walss Rodriguez, RJ | 1 |
| Flores Padilla, LM | 1 |
| Sherman, RC | 1 |
| Langley-Evans, SC | 1 |
| Bortolus, R | 1 |
| Ricci, E | 1 |
| Chatenoud, L | 1 |
| Parazzini, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Vaginal Indomethacin Versus Oral Nifedipine for Preterm Labor; a Randomized Controlled Trial[NCT04404686] | Phase 2/Phase 3 | 300 participants (Anticipated) | Interventional | 2020-10-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 trials available for nifedipine and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Maintenance tocolysis with nifedipine in threatened preterm labour: 2-year follow up of the offspring in the APOSTEL II trial.
Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Fetal Membranes, Premature Rupture; Follow | 2016 |
Effect of antenatal tocolysis on neonatal outcomes.
Topics: Female; Gestational Age; Humans; Indomethacin; Infant, Newborn; Infant, Newborn, Diseases; Magnesium | 2012 |
Long-term follow up of children exposed in utero to nifedipine or ritodrine for the management of preterm labour.
Topics: Adult; Affective Symptoms; Child; Child Behavior Disorders; Female; Follow-Up Studies; Gestational A | 2006 |
[Management of severe pre-eclampsia/eclampsia. Comparison between nifedipine and hydralazine as antihypertensive agents].
Topics: Administration, Sublingual; Antihypertensive Agents; Apgar Score; Drug Evaluation; Eclampsia; Female | 1993 |
Nifedipine administered in pregnancy: effect on the development of children at 18 months.
Topics: Calcium Channel Blockers; Child Development; Female; Follow-Up Studies; Humans; Hypertension; Infant | 2000 |
5 other studies available for nifedipine and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Cumulative Risk of the Oxytocin Receptor Gene Interacts with Prenatal Exposure to Oxytocin Receptor Antagonist to Predict Children's Social Communication Development.
Topics: Adult; Autism Spectrum Disorder; Child; Child, Preschool; Communication Disorders; Drug Therapy, Com | 2019 |
High-sucrose diets in pregnancy alter angiotensin II-mediated pressor response and microvessel tone via the PKC/Cav1.2 pathway in rat offspring.
Topics: Angiotensin II; Animals; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Dietary | 2014 |
Maternal antihypertensive drugs may influence cerebral oxygen extraction in preterm infants during the first days after birth.
Topics: Antihypertensive Agents; Case-Control Studies; Cerebral Cortex; Cerebrovascular Circulation; Female; | 2013 |
Effect of nifedipine treatment (imprinting) of rat feti and newborns on the responsiveness of adult rat's uterus. Extension of the imprinting theory.
Topics: Animals; Animals, Newborn; Female; Fetus; In Vitro Techniques; Nifedipine; Oxytocin; Pregnancy; Pren | 1995 |
Antihypertensive treatment in early postnatal life modulates prenatal dietary influences upon blood pressure in the rat.
Topics: Analysis of Variance; Angiotensin Receptor Antagonists; Animal Nutritional Physiological Phenomena; | 2000 |