nifedipine has been researched along with Decerebrate Posturing in 28 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of two dihydropyridine type calcium entry blockers, nilvadipine and nicardipine hydrochloride (nicardipine), on the liberation of free fatty acids (FFAs) were investigated using an experimental model of global cerebral ischemia in rats, and were compared with their pharmacokinetic properties." | 7.68 | Nilvadipine as a neuroprotective calcium entry blocker in a rat model of global cerebral ischemia. A comparative study with nicardipine hydrochloride. ( Fujiwara, T; Kohsaka, M; Mori, J; Satoh, H; Sogabe, K; Takakura, S; Tokuma, Y; Totsuka, Z, 1992) |
| "The effects of two dihydropyridine type calcium entry blockers, nilvadipine and nicardipine hydrochloride (nicardipine), on the liberation of free fatty acids (FFAs) were investigated using an experimental model of global cerebral ischemia in rats, and were compared with their pharmacokinetic properties." | 3.68 | Nilvadipine as a neuroprotective calcium entry blocker in a rat model of global cerebral ischemia. A comparative study with nicardipine hydrochloride. ( Fujiwara, T; Kohsaka, M; Mori, J; Satoh, H; Sogabe, K; Takakura, S; Tokuma, Y; Totsuka, Z, 1992) |
| "Pretreatment with phenoxybenzamine accentuated the inhibitory actions of captopril and a combination of phenoxybenzamine and captopril significantly increased the ED50 without altering the maximum response." | 1.29 | Pressor responses to the alpha 1-adrenoceptor agonist cirazoline: effects of captopril, phenoxybenzamine and nifedipine. ( Tabrizchi, R; Triggle, CR, 1994) |
| "Treatment with captopril was found to attenuate pressor responses produced by the administration of either alpha 1- or alpha 2-adrenoceptor agonists, resulting in the displacement to the right of the agonist dose-response curves and significantly increasing the calculated ED50 values." | 1.28 | The interrelationship between the effects of captopril and nifedipine on pressor responses elicited by selective alpha-adrenoceptor agonists in the pithed rat preparation. ( Tabrizchi, R; Triggle, CR, 1992) |
| " Administration of nifedipine to Sprague-Dawley and WKY rats did not affect the dose-response curve to AVP, but nifedipine administration in SHR led to a significant inhibition of the pressor responses to AVP." | 1.28 | Pressor actions of arginine vasopressin in pithed Sprague-Dawley, Wistar-Kyoto and spontaneously hypertensive rats before and after treatment with nifedipine or pertussis toxin. ( Tabrizchi, R; Triggle, CR, 1991) |
| " The ED50 value for the dose-response curves to B-HT 920 and St587 were found to be significantly increased after the administration of staurosporine." | 1.28 | Effects of staurosporine on the pressor responses to alpha-adrenoceptor agonists in pithed rats: a comparison with nifedipine. ( Tabrizchi, R; Triggle, CR, 1991) |
| " Treatment with pertussis toxin caused the DBP dose-response curve to SRTX-b to be displaced to the right." | 1.28 | Effects of nifedipine, BAY K 8644, and pertussis toxin on pressor response to sarafotoxin-b in pithed rats. ( Tabrizchi, R; Triggle, CR, 1990) |
| "Nifedipine effects were additive with an increase in the EC50 values as well as reduction in the maximum response after pretreatment with benextramine (3 and 6 mg/Kg)." | 1.28 | Benextramine and nifedipine distinguish between sub-classes of alpha 1-adrenoceptors. ( Tabrizchi, R; Triggle, CR, 1989) |
| " Only a leftward shift of the dose-response curves was observed, which was most pronounced for (-)-phenylephrine and Sgd 101/75." | 1.27 | Interactions between the putative calcium entry promotor Bay k 8644 and pressor responses produced by alpha 1- and alpha 2-adrenoceptor agonists in the pithed normotensive rat. ( de Jonge, A; Mathy, MJ; Thoolen, MJ; Timmermans, PB; van Heiningen, PN; van Zwieten, PA; Wilffert, B, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (50.00) | 18.7374 |
| 1990's | 13 (46.43) | 18.2507 |
| 2000's | 1 (3.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wilffert, B | 6 |
| van Heiningen, PN | 2 |
| Mathy, MJ | 5 |
| de Jonge, A | 6 |
| Thoolen, MJ | 8 |
| Timmermans, PB | 8 |
| van Zwieten, PA | 7 |
| Davidesko, D | 1 |
| Batink, HD | 1 |
| Roquebert, J | 1 |
| Malek, A | 1 |
| Gomond, P | 1 |
| Demichel, P | 1 |
| Tabrizchi, R | 8 |
| Lupichuk, SM | 1 |
| Triggle, CR | 7 |
| Vargas, HM | 1 |
| Zhou, L | 1 |
| Gorman, AJ | 1 |
| Ichihara, K | 1 |
| Okumura, K | 1 |
| Mori, H | 1 |
| Nagasaka, M | 1 |
| Bernardi, M | 1 |
| Deslauriers, R | 1 |
| Docherty, J | 1 |
| Rossi, C | 1 |
| Rossini, L | 1 |
| Rossini, P | 1 |
| Tonnini, C | 1 |
| Martín, E | 1 |
| Sevilla, MA | 1 |
| Morán, A | 1 |
| Martín, ML | 1 |
| Román, LS | 1 |
| Motley, ED | 1 |
| Ruffolo, RR | 1 |
| Nichols, AJ | 1 |
| Takakura, S | 1 |
| Sogabe, K | 1 |
| Satoh, H | 1 |
| Mori, J | 1 |
| Fujiwara, T | 1 |
| Totsuka, Z | 1 |
| Tokuma, Y | 1 |
| Kohsaka, M | 1 |
| Kontani, H | 1 |
| Nakagawa, M | 1 |
| Takeno, S | 1 |
| Sakai, T | 1 |
| Spedding, M | 1 |
| DiFrancesco, GF | 1 |
| Mir, AK | 1 |
| Petty, MA | 1 |
| Berg, C | 1 |
| Gittos, M | 1 |
| Haass, M | 1 |
| Kopin, IJ | 1 |
| Goldstein, DS | 1 |
| Zukowska-Grojec, Z | 1 |
| Jim, KF | 1 |
| Macia, RA | 1 |
| Matthews, WD | 1 |
| Beckeringh, JJ | 1 |
| Bulloch, JM | 1 |
| McGrath, JC | 1 |
28 other studies available for nifedipine and Decerebrate Posturing
| Article | Year |
|---|---|
Interactions between the putative calcium entry promotor Bay k 8644 and pressor responses produced by alpha 1- and alpha 2-adrenoceptor agonists in the pithed normotensive rat.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1984 |
Sgd 101/75 is distinguished from other selective alpha 1-adrenoceptor agonists by the inhibition of its pressor responses by calcium entry blockade and vasodilatation in pithed rats and cats.
Topics: Adrenergic alpha-Agonists; Albuterol; Animals; Blood Pressure; Calcium Channel Blockers; Cats; Cloni | 1983 |
Interaction between the calcium entry blocker nifedipine with the alpha 1-adrenoreceptor-mediated increase in diastolic pressure elicited by catecholamines.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Catecholamines; Decerebrate State; Diastole; Dos | 1984 |
Lack of relationship between intrinsic activity and susceptibility of pressor responses to blockade by nifedipine among the alpha 2-adrenoceptor agonists B-HT 920 and B-HT 958.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Pressure; Decerebrate State; Dose-Response Relat | 1984 |
Invariable susceptibility to blockade by nifedipine of vasoconstriction to various alpha 2-adrenoceptor agonists in pithed rats.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Decerebrate State; Male; Nifedipine; Rats; Rats, | 1984 |
Effect of dihydroergocristine on blood pressure and activity at peripheral alpha-adrenoceptors in pithed rats.
Topics: Animals; Blood Pressure; Decerebrate State; Dihydroergotoxine; Dose-Response Relationship, Drug; Ele | 1984 |
The effects of losartan and captopril on vasopressor actions of cirazoline in the absence and presence of SZL-49 and nifedipine.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Antihyperten | 1995 |
Pressor responses to the alpha 1-adrenoceptor agonist cirazoline: effects of captopril, phenoxybenzamine and nifedipine.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Captopril; Decerebrate State; Dose-Response Rela | 1994 |
Role of vascular alpha-1 adrenoceptor subtypes in the pressor response to sympathetic nerve stimulation in the pithed rat.
Topics: Animals; Blood Pressure; Blood Vessels; Clonidine; Decerebrate State; Dioxanes; Electric Stimulation | 1994 |
Effects of MPC-1304, a novel Ca2+ entry blocker, on alpha-adrenoceptor-mediated pressor responses in pithed rats.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Animals; Blood Pressure; Brimonidine Tartrate; Calc | 1993 |
Spectral analysis of intercycle heart fluctuations in Xenopus laevis, conscious or spinalized, treated with calcium channel blockers. Part I.
Topics: Animals; Calcium Channel Blockers; Decerebrate State; Diltiazem; Dose-Response Relationship, Drug; E | 1997 |
Effects of P5, a novel oxazolo(3,2-a)pyridine derivative with a long-acting antihypertensive activity, on different agonist-mediated pressor responses in pithed rats.
Topics: Adrenergic alpha-Agonists; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pr | 2001 |
The effect of pertussis toxin treatment on alpha-1-adrenoceptor-mediated pressor responses in the pithed rat: dependence on agonist efficacy but not chemical class.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Decerebrate State; GTP-Binding Proteins; Male; N | 1992 |
The interrelationship between the effects of captopril and nifedipine on pressor responses elicited by selective alpha-adrenoceptor agonists in the pithed rat preparation.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Pressure; Captopril; Clonidine; Decerebrate Stat | 1992 |
Nilvadipine as a neuroprotective calcium entry blocker in a rat model of global cerebral ischemia. A comparative study with nicardipine hydrochloride.
Topics: Animals; Brain; Brain Ischemia; Calcium Channel Blockers; Decerebrate State; Fatty Acids, Nonesterif | 1992 |
Pressor actions of arginine vasopressin in pithed Sprague-Dawley, Wistar-Kyoto and spontaneously hypertensive rats before and after treatment with nifedipine or pertussis toxin.
Topics: Animals; Arginine Vasopressin; Decerebrate State; Dose-Response Relationship, Drug; Hypertension; Ma | 1991 |
Effects of staurosporine on the pressor responses to alpha-adrenoceptor agonists in pithed rats: a comparison with nifedipine.
Topics: Adrenergic alpha-Agonists; Alkaloids; Animals; Azepines; Blood Pressure; Clonidine; Decerebrate Stat | 1991 |
Comparison between the vasoactive actions of endothelin and arginine vasopressin in pithed rats after pretreatment with BAY K 8644, nifedipine or pertussis toxin.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1990 |
Effects of nifedipine, BAY K 8644, and pertussis toxin on pressor response to sarafotoxin-b in pithed rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1990 |
Evaluation of drugs for treatment of urinary bladder dysfunction in conscious rats with intact pelvic nerve and after resection of the left pelvic nerve.
Topics: Animals; Atropine; Butylamines; Decerebrate State; Drug Evaluation; Male; Mandelic Acids; Nifedipine | 1990 |
MDL 72567, a dihydropyridine calcium-antagonist, that causes vasodilation and direct sinus bradycardia.
Topics: Animals; Bradycardia; Calcium Channel Blockers; Calcium Channels; Decerebrate State; Dihydropyridine | 1987 |
Benextramine and nifedipine distinguish between sub-classes of alpha 1-adrenoceptors.
Topics: Animals; Blood Pressure; Body Temperature; Cystamine; Decerebrate State; Diastole; Male; Methoxamine | 1989 |
Equal potency of nifedipine to inhibit alpha 1-(dobutamine and BDF 6143) and alpha 2-adrenoceptor (B-HT 920) induced pressor responses in pithed rats; lack of effect of phenoxybenzamine.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Pressure; Decerebrate State; Dobutamine; Dose-Re | 1987 |
Effects of the irreversible alpha-adrenoceptor antagonists phenoxybenzamine and benextramine on the effectiveness of nifedipine in inhibiting alpha 1- and alpha 2-adrenoceptor mediated vasoconstriction in pithed rats.
Topics: Animals; Azepines; Clonidine; Cystamine; Decerebrate State; Diastole; Dose-Response Relationship, Dr | 1985 |
Differential inhibition of alpha adrenoceptor-mediated pressor responses by rat atrial natriuretic peptide in the pithed rat.
Topics: Adrenergic alpha-Antagonists; Animals; Atrial Natriuretic Factor; Blood Pressure; Clonidine; Decereb | 1985 |
Role of receptor reserve in the inhibition of alpha-1 adrenoceptor-mediated pressor responses by calcium antagonists in the pithed rat.
Topics: 2-Naphthylamine; Animals; Blood Pressure; Calcium Channel Blockers; Chemical Phenomena; Chemistry; D | 1986 |
Sensitivity of alpha-1 adrenoceptor-mediated pressor responses to inhibition by Ca++ entry blockers in the pithed rat: arguments against the role of receptor reserve.
Topics: Animals; Blood Pressure; Decerebrate State; Diastole; Male; Nifedipine; Phenoxybenzamine; Phenylephr | 1987 |
Selective blockade by nifedipine of 'purinergic' rather than adrenergic nerve-mediated vasopressor responses in the pithed rat.
Topics: Adenosine Triphosphate; Animals; Decerebrate State; Gallamine Triethiodide; Halothane; Nifedipine; P | 1988 |