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nifedipine and Cystic Fibrosis of Pancreas

nifedipine has been researched along with Cystic Fibrosis of Pancreas in 8 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Research Excerpts

ExcerptRelevanceReference
"Previous studies have indicated that there is weak genetic linkage between the defective gene in cystic fibrosis (CFTR) and the gene encoding the nifedipine metabolizing enzyme P4503A4 which are both located on chromosome 7."7.68Deficient nifedipine oxidation: a rare inherited trait associated with cystic fibrosis kindreds. ( Allen, J; Bilton, D; Braganza, JM; Daly, AK; Idle, JR; Knight, AD; Salh, BS; Webb, AK, 1992)
"The acute effects of oxygen, nifedipine, and diltiazem were studied in eight patients with cystic fibrosis and mild pulmonary hypertension, to assess the possibility of relieving the latter before the occurrence of irreversible vascular changes."7.67Acute effects of oxygen, nifedipine, and diltiazem in patients with cystic fibrosis and mild pulmonary hypertension. ( Bossuyt, A; Dab, I; Davidson, A, 1989)
"Nifedipine has recently been reported to reduce pulmonary artery pressure and pulmonary vascular resistance during rest and exercise in adult patients with hypoxic pulmonary hypertension from chronic obstructive pulmonary disease."5.27Nifedipine inhibits hypoxic pulmonary vasoconstriction during rest and exercise in patients with cystic fibrosis and cor pulmonale. ( Fitzpatrick, S; Kennedy, TP; Michael, JR; Rosenstein, BJ, 1984)
"Previous studies have indicated that there is weak genetic linkage between the defective gene in cystic fibrosis (CFTR) and the gene encoding the nifedipine metabolizing enzyme P4503A4 which are both located on chromosome 7."3.68Deficient nifedipine oxidation: a rare inherited trait associated with cystic fibrosis kindreds. ( Allen, J; Bilton, D; Braganza, JM; Daly, AK; Idle, JR; Knight, AD; Salh, BS; Webb, AK, 1992)
"The acute effects of oxygen, nifedipine, and diltiazem were studied in eight patients with cystic fibrosis and mild pulmonary hypertension, to assess the possibility of relieving the latter before the occurrence of irreversible vascular changes."3.67Acute effects of oxygen, nifedipine, and diltiazem in patients with cystic fibrosis and mild pulmonary hypertension. ( Bossuyt, A; Dab, I; Davidson, A, 1989)
"Nifedipine has recently been reported to reduce pulmonary artery pressure and pulmonary vascular resistance during rest and exercise in adult patients with hypoxic pulmonary hypertension from chronic obstructive pulmonary disease."1.27Nifedipine inhibits hypoxic pulmonary vasoconstriction during rest and exercise in patients with cystic fibrosis and cor pulmonale. ( Fitzpatrick, S; Kennedy, TP; Michael, JR; Rosenstein, BJ, 1984)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19904 (50.00)18.7374
1990's2 (25.00)18.2507
2000's0 (0.00)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Budriesi, R1
Ioan, P1
Leoni, A1
Pedemonte, N1
Locatelli, A1
Micucci, M1
Chiarini, A1
Galietta, LJ1
Chung, WJ1
Goeckeler-Fried, JL1
Havasi, V1
Chiang, A1
Rowe, SM1
Plyler, ZE1
Hong, JS1
Mazur, M1
Piazza, GA1
Keeton, AB1
White, EL1
Rasmussen, L1
Weissman, AM1
Denny, RA1
Brodsky, JL1
Sorscher, EJ1
Michael, JR1
Kennedy, TP1
Fitzpatrick, S1
Rosenstein, BJ1
Daly, AK1
Salh, BS1
Bilton, D1
Allen, J1
Knight, AD1
Webb, AK1
Braganza, JM1
Idle, JR1
Eichler, I1
Burghuber, OC1
Götz, M1
Davidson, A1
Bossuyt, A1
Dab, I1
Hussein, A1
Koch, I1
Schmidt-Redemann, B1
Geggel, RL1
Dozor, AJ1
Fyler, DC1
Reid, LM1

Other Studies

8 other studies available for nifedipine and Cystic Fibrosis of Pancreas

ArticleYear
Cystic fibrosis: a new target for 4-Imidazo[2,1-b]thiazole-1,4-dihydropyridines.
    Journal of medicinal chemistry, 2011, Jun-09, Volume: 54, Issue:11

    Topics: Amino Acid Sequence; Animals; Antihypertensive Agents; Bacterial Proteins; Cell Line; Cystic Fibrosi

2011
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regu

2016
Nifedipine inhibits hypoxic pulmonary vasoconstriction during rest and exercise in patients with cystic fibrosis and cor pulmonale.
    The American review of respiratory disease, 1984, Volume: 130, Issue:3

    Topics: Adult; Combined Modality Therapy; Cystic Fibrosis; Hemodynamics; Humans; Hypoxia; Lung; Male; Nifedi

1984
Deficient nifedipine oxidation: a rare inherited trait associated with cystic fibrosis kindreds.
    Pharmacogenetics, 1992, Volume: 2, Issue:1

    Topics: Adolescent; Adult; Aryl Hydrocarbon Hydroxylases; Base Sequence; Cystic Fibrosis; Cytochrome P-450 C

1992
Acute effects on pulmonary haemodynamics of nifedipine in adult patients with cystic fibrosis.
    European journal of clinical pharmacology, 1990, Volume: 39, Issue:6

    Topics: Adult; Blood Pressure; Cystic Fibrosis; Hemodynamics; Humans; Hypoxia; Nifedipine; Pulmonary Alveoli

1990
Acute effects of oxygen, nifedipine, and diltiazem in patients with cystic fibrosis and mild pulmonary hypertension.
    Pediatric pulmonology, 1989, Volume: 6, Issue:1

    Topics: Adolescent; Adult; Airway Resistance; Cystic Fibrosis; Diltiazem; Female; Hemodynamics; Humans; Hype

1989
[Noninvasive methods for assessing the effect of nifedipine on cardiorespiratory function in a patient with cystic fibrosis].
    Praxis und Klinik der Pneumologie, 1988, Volume: 42, Issue:8

    Topics: Adult; Cystic Fibrosis; Humans; Hypertension, Pulmonary; Male; Nifedipine; Pulmonary Heart Disease;

1988
Effect of vasodilators at rest and during exercise in young adults with cystic fibrosis and chronic cor pulmonale.
    The American review of respiratory disease, 1985, Volume: 131, Issue:4

    Topics: Adult; Chronic Disease; Cystic Fibrosis; Exercise Test; Female; Hemodynamics; Humans; Hydralazine; M

1985