nifedipine and Coronary Heart Disease studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Research Excerpts

Excerpt	Relevance	Reference
"The present study was carried out to investigate exercise test results and the outcome of the quality of life after administration of trapidil (CAS 15421-84-8, Rocornal) or nifedipine (CAS 21829-25-4) to patients with coronary heart disease."	9.08	[The effects of treatment with trapidil compared to nifedipine on physical, emotional and cognitive exercise tolerance in patients with coronary heart disease]. ( Assmann, I; Burkard, G; Lehrl, S; Strösser, W, 1996)
"Patients with stable, effort-induced angina pectoris and a typical combination of anginal pain and ischemic ST depression in exercise tolerance tests were randomized to treatment for 8 weeks with nicorandil (a newly developed antianginal and anti-ischemic drug) or nifedipine."	9.07	Antianginal and anti-ischemic efficacy of nicorandil compared with nifedipine in patients with angina pectoris and coronary heart disease: a double-blind, randomized, multicenter study. ( Diderholm, E; Frithz, G; Gudbrandsson, T; Hedbäck, B; Höglund, C; Moelstad, P; Perk, J; Sverrisson, JT; Ulvenstam, G, 1992)
"In this single centre prospective, double blind study, 98 patients with suspected acute myocardial infarction (AMI) were randomized, within six hours, to nifedipine 10 mg (46 patients) or placebo (52 patients) both administered sublingually."	9.06	Effect of early treatment with nifedipine in suspected acute myocardial infarction. ( Branagan, JP; Collins, WC; Kelly, P; McCafferty, D; Walsh, K; Walsh, MJ, 1986)
"The short-term effect of oral nifedipine on effort tolerance was tested in 10 patients with effort angina pectoris and a positive effort test (GXT)."	9.06	Short-term effect of nifedipine on effort tolerance in patients with angina pectoris. ( Flugelman, MY; Gotsman, MS; Halon, DA; Shefer, A; Witt, H, 1986)
"The effectiveness of verapamil in the management of patients with unstable angina pectoris associated with obstructive coronary artery disease was evaluated in 2 double-blind placebo-controlled randomized clinical trials."	9.05	Verapamil therapy for unstable angina pectoris: review of double-blind placebo-controlled randomized clinical trials. ( Conti, CR; Mehta, J, 1982)
"In 10 patients with angina pectoris and angiographically proven coronary heart disease, the effect of 60 mg of orally administered diltiazem (D) and 20 mg of nifedipine (N) on heart rate and exercise-induced ST-segment depression was investigated under randomized double-blind conditions."	9.05	[The effect of diltiazem and nifedipine on exercise-induced ST-segment depression and heart rate in patients with coronary heart disease (author's transl)]. ( Berlad, T; Hopf, R; Kaltenbach, M; Kober, G, 1981)
"A single blind randomized parallel study designed to assess the anti-anginal efficacy of pindolol and nifedipine was carried out in 42 ambulatory coronary patients with stable angina pectoris."	9.04	Therapeutic effects of pindolol and nifedipine in patients with stable angina pectoris and asymptomatic resting ischemia. ( Amrein, R; Castagnoli, E; Chu, D; Cocco, G; Strozzi, C, 1979)
"In patients with coronary disease, the use of short-acting nifedipine in moderate to high doses causes an increase in total mortality."	8.79	Nifedipine. Dose-related increase in mortality in patients with coronary heart disease. ( Furberg, CD; Meyer, JV; Psaty, BM, 1995)
"Nifedipine antagonises influx of calcium through cell membrane slow channels, and sustained release formulations of the calcium channel blocker have been shown to be effective in the treatment of mild to moderate hypertension and both stable and variant angina pectoris."	8.78	Sustained release nifedipine formulations. An appraisal of their current uses and prospective roles in the treatment of hypertension, ischaemic heart disease and peripheral vascular disorders. ( Brogden, RN; Murdoch, D, 1991)
"Effects of CD-832 on isoproterenol (ISO)-induced myocardial ischemia were studied in dogs with partial coronary stenosis of the left circumflex coronary artery and findings were compared with those for nifedipine or diltiazem."	7.69	Effects of a new calcium antagonist, CD-832, on isoproterenol-induced myocardial ischemia in dogs with partial coronary stenosis. ( Araki, H; Higuchi, S; Kishi-Tanikawa, S; Takahashi, K; Takahashi, T; Tsuchida, K, 1996)
"Acute effects of Nifedipine, a calcium channel blocking agent (CCBA), on central haemodynamics in patients with severe hypertension and angiographically proved coronary artery disease (CAD) has been studied using Nuclear Ventriculography (MUGA)."	7.68	Nuclear imaging study of nifedipine induced modulations of central haemodynamics in severe hypertension with and without coronary artery disease. ( Bhatia, ML; Jangid, DR; Kasliwal, RR; Trehan, N, 1993)
"Haemodynamic effects of nifedipine (NIF) tablets were studied for 12 h in 10 patients with severe congestive heart failure due to ischaemic heart disease."	7.68	Haemodynamic effects of slow-release nifedipine in severe congestive heart failure due to ischaemic heart disease. ( Rossi, A; Ziacchi, V, 1990)
"In 22 of 27 cases of congestive heart failure (CHF) treated with nifedipine (NIF), significant improvements in resting hemodynamics were noticed."	7.68	Nifedipine pharmacodynamics and pharmacokinetics in treatment of congestive heart failure. ( Chen, DG; Chen, K; Feng, QP; Wang, ZQ, 1990)
"With this study including 9 patients with angiographically proven coronary heart disease it could be shown that a monotherapy with nifedipine in the galenic preparation as Adalat SL (Bayer AG, Leverkusen, FRG) is efficient in reducing myocardiac ischemia and concomitantly raising working capacity during bicycle ergometry as well after first time application of this drug as after continuous therapy with 1 tablet twice daily during 4 weeks."	7.68	[Modification of physical fitness of patients with coronary heart disease with nifedipine during a stay at altitude]. ( Deuber, HJ, 1990)
"The antiarrhythmic activity of the calcium entry blockers, verapamil, nifedipine and prenylamine, was assessed against arrhythmias occurring during 20 min of acute occlusion, or upon rapid reperfusion of the left anterior descending coronary artery (LAD) in anesthetized pigs."	7.67	Acute coronary artery occlusion-reperfusion arrhythmias in pigs: antiarrhythmic and antifibrillatory evaluation of verapamil, nifedipine, prenylamine and propranolol. ( Bergey, JL; McCallum, JD; Nocella, K; Wendt, RL, 1984)
"Nifedipine-induced gingival hyperplasia was first reported in 1984."	7.67	Nifedipine-induced gingival hyperplasia. ( Yusof, WZ, 1989)
"Combined nitrate/beta-blocker/nifedipine therapy is commonly used to treat refractory angina pectoris."	7.67	Nifedipine-induced hypotension and myocardial ischemia in refractory angina pectoris. ( Boden, WE; Bough, EW; Korr, KS, 1985)
"The comparative effects of the calcium-antagonists gallopamil and nifedipine on ischemia-induced and reperfusion-induced ventricular arrhythmias, particularly ventricular fibrillation (VF), were assessed in a total of 40 mongrel dogs in two experimental preparations."	7.67	Calcium antagonists and acute myocardial ischemia: comparative effects of gallopamil and nifedipine on ischemia-induced and reperfusion-induced ventricular arrhythmias, epicardial conduction times, and ventricular fibrillation thresholds. ( Bender, F; Gülker, H; Haverkamp, W; Hindricks, G, 1987)
" Nifedipine and DHM9 (carboxymethyl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate) were studied for their effects on arrhythmias resulting from regional myocardial ischaemia in conscious rats, and for their effects on left ventricular developed pressure in vitro."	7.67	The mechanism of action of calcium antagonists on arrhythmias in early myocardial ischaemia: studies with nifedipine and DHM9. ( Curtis, MJ; Walker, MJ, 1988)
"Acute nifedipine tests and courses of nifedipine treatment were conducted in 30 patients with essential hypertension."	7.67	[Effect of an acute pharmacological test and a course of treatment with nifedipine on cerebral hemodynamic indices and information processing efficiency in hypertension patients]. ( Liventseva, MM; Nechesova, TA; Pavlova, AI; Sidorenko, GI, 1988)
"To examine whether nicardipine, a dihydropyridine derivative, limits size of myocardial infarction, and to compare the protective effects of nicardipine administered before and early and late after coronary artery occlusion, 99mTc-labeled albumin microspheres were injected into the left atrium during 5 min temporary coronary artery occlusion to determine the extent of the hypoperfused zone (the area at risk)."	7.67	Comparative effects of nicardipine, a new calcium antagonist, on size of myocardial infarction after coronary artery occlusion in dogs. ( Endo, T; Fujita, S; Hayakawa, H; Iida, N; Kikuchi, K; Kiuchi, K; Nejima, J; Okumura, H, 1986)
"In conclusion, we observed first that nifedipine is highly efficacious in preventing the coronary vasospasm of Prinzmetal's variant angina."	7.66	Nifedipine therapy for coronary vasospasm. ( Antman, EM; Muller, JE; Stone, PH, 1983)
"We report clinical experience with the coronary vasodilator nifedipine in 127 patients with symptoms of myocardial ischemia associated with electrocardiographic or angiographic evidence, or both, of coronary-artery spasm."	7.66	Nifedipine therapy for coronary-artery spasm. Experience in 127 patients. ( Achuff, S; Antman, E; Braunwald, E; Geltman, E; Goldberg, S; Heupler, F; Kerin, NZ; Liang, CS; MacAlpin, R; Muller, J; Neff, RK; Reichek, N; Rubenfire, M; Tabatznik, B, 1980)
"Nifedipine was evaluated in the management of eight patients with intractable coronary arterial spasm."	7.66	Nifedipine therapy for refractory coronary arterial spasm. ( Heupler, FA; Proudfit, WL, 1979)
"Nifedipine was administered in a dose of 30 mg orally to 14 patients with coronary heart disease and clinical evidence of left heart failure."	7.66	[The effect of nifedipine on the pulmonary artery pressure in patients with coronary heart disease (author's transl)]. ( Beck, OA; Hochrein, H, 1978)
"To compare the negative inotropic effects of the four dihydropyridine-calcium-channel-blockers nifedipine (NIF), isradipine (ISR), nisoldipine (NIS) and felodipine (FEL) in man, the drugs were infused within 30 min intravenously in an equihypotensive dosage (NIF 2 mg, ISR 0."	6.67	[Comparison of the cardiodepressive effects of nifedipine, isradipine, nisoldipine and felodipine in patients with coronary heart disease]. ( Ickrath, O; Karsch, KR; Mauser, M; Voelker, W, 1993)
"Nifedipine was ineffective, particularly in patients with angina predominantly on effort and with a moderate to severe reduction in exercise tolerance."	6.67	Transient myocardial ischemia during daily life in rest and exertional angina pectoris and comparison of effectiveness of metoprolol versus nifedipine. ( Ardissino, D; Egstrup, K; Feruglio, GA; Giordano, MP; Marraccini, P; Roncarolo, P; Rosenfeld, M; Savonitto, S; Slavich, G; Wahlqvist, I, 1991)
" In this dosage peripheral effects--decrease of peripheral vascular resistance and mean aortic pressure--did not differ significantly between them."	6.67	[Myocardial effects of the calcium antagonists nifedipine, nisoldipine and isradipine in coronary heart disease]. ( Ickrath, O; Karsch, KR; Kühlkamp, V; Mauser, M; Voelker, W, 1990)
"For effective treatment of coronary heart disease with calcium antagonists, knowledge of both the dose-response relationship of a remedy and equipotent dosage for comparison of different drugs is necessary."	6.66	[Dose-response relation of gallopamil in comparison with nifedipine, diltiazem and tiapamil in patients with coronary heart disease]. ( Fleischer, K; Forster, A; Hopf, R; Kaltenbach, M; Mohler, C; Schulz, PC, 1989)
"Calcium antagonists are used in the treatment of hypertension and angina."	6.44	The ACTION study: nifedipine in patients with symptomatic stable angina and hypertension. ( Coca, A; Sierra, C, 2008)
" However, the short-acting formulations of nifedipine had pharmacokinetic properties that were far from ideal and in 1995, several studies involving various dosing regimens reported possible dangerous effects in secondary prevention."	6.44	Nifedipine Gastrointestinal Therapeutic System (GITS) in the treatment of coronary heart disease and hypertension. ( Dunselman, PH; Kragten, JA, 2007)
" In a double-blind study of ten patients with stable angina pectoris treated with nifedipine, propranolol, and atenolol, smoking was found to have direct and adverse effects on the heart and to interfere with the efficacy of all three antianginal drugs, but with that of nifedipine the most."	6.16	Smoking, catecholamines, and the ischemic myocardium. ( Fox, KM, 1988)
" For both drug classes, we suggest that long-acting agents be considered, providing therapeutic coverage well beyond the normal dosing interval."	5.29	1,4-Dihydropyridines versus beta-blockers for hypertension: are either safe for the heart? ( Leenen, FH, 1996)
"The number of reperfusion arrhythmias was also significantly lower in the treated animals."	5.27	Nifedipine with and without propranolol in the treatment of myocardial ischemia: effect on ventricular arrhythmias and recovery of regional wall function. ( ten Cate, FJ; Verdouw, PD; Wolffenbuttel, BH, 1983)
"Amlodipine is a long-acting dihydropyridine-based calcium antagonist developed for use on a once-a-day basis."	5.27	The effect of amlodipine on hypertension-induced cardiac hypertrophy and reperfusion-induced calcium overload. ( Nayler, WG, 1988)
"The hypotensive effect of nifedipine (a Ca2+-antagonist) was studied in acute tests and during the long-term administration of the drug together with propranolol."	5.26	Hypotensive action of nifedipine (Ca2+-antagonist) and propranolol in acute trials and its long-term therapy of hypertensive coronary heart disease patients. ( Aoki, K; Kato, K; Kawaguchi, Y; Kondo, S; Mochizuki, A; Sato, K; Yamamoto, M, 1981)
"The present study was carried out to investigate exercise test results and the outcome of the quality of life after administration of trapidil (CAS 15421-84-8, Rocornal) or nifedipine (CAS 21829-25-4) to patients with coronary heart disease."	5.08	[The effects of treatment with trapidil compared to nifedipine on physical, emotional and cognitive exercise tolerance in patients with coronary heart disease]. ( Assmann, I; Burkard, G; Lehrl, S; Strösser, W, 1996)
" Angiotensin converting enzyme inhibitors (ACE-I) significantly retarded the development of end-stage renal failure compared to antihypertensives other than ACE-I (mostly nifedipine), and the effect was evident particularly in patients with proteinuria below the median (2."	5.08	Predictors of the progression of diabetic nephropathy and the beneficial effect of angiotensin-converting enzyme inhibitors in NIDDM patients. ( Babazono, T; Hirayama, M; Ishii, A; Omori, Y; Takahashi, C; Takeda, M; Tomonaga, O; Ujihara, U; Yokoyama, H, 1997)
" We studied the short effects of oral administration of nifedipine (10 mg) and propranolol (80 mg) alone and in combination in 15 elderly patients with chronic exertional angina pectoris in a double-blind, randomized, cross-over study."	5.07	[Acute effects of propranolol and its association with nifedipine in aged patients with effort stable angina. Randomized double-blind crossover study, under placebo control]. ( Cicatiello, AM; De Rosa, ML; Di Palma, A; Iannuzzi, L; Lirato, C; Pandolfi, E; Parlati, S; Santamaria, F; Sestito, M, 1993)
"These data suggest that (1) dobutamine stress can be used to induce cardiac ischemia in elderly patients with coronary artery disease, (2) nifedipine-GITS provides symptomatic angina relief in elderly patients, (3) peripheral edema is frequent in elderly patients on nifedipine-GITS, and (4) ultrafast computed cine-tomography testing can be used to assess ventricular performance, but current methodology may not detect perfusion or wall motion abnormalities during angina."	5.07	Early experience with dobutamine stress testing and cardiac cine-tomographic imaging in the elderly: antianginal effects of nifedipine-GITS. ( Abbott, J; Caputo, G; Schwartz, JB, 1993)
"Patients with stable, effort-induced angina pectoris and a typical combination of anginal pain and ischemic ST depression in exercise tolerance tests were randomized to treatment for 8 weeks with nicorandil (a newly developed antianginal and anti-ischemic drug) or nifedipine."	5.07	Antianginal and anti-ischemic efficacy of nicorandil compared with nifedipine in patients with angina pectoris and coronary heart disease: a double-blind, randomized, multicenter study. ( Diderholm, E; Frithz, G; Gudbrandsson, T; Hedbäck, B; Höglund, C; Moelstad, P; Perk, J; Sverrisson, JT; Ulvenstam, G, 1992)
"Altogether 12 patients with stable angina pectoris of effort were examined for the efficacy of nicardipine as compared to nifedipine and placebo by means of pharmacodynamic studies using treadmill."	5.06	[The comparative efficacy of nicardipine and nifedipine in stenocardia patients]. ( Martsevich, SIu; Metelitsa, VI; Simkhaev, LS; Slastnikova, ID, 1990)
"We performed a randomized study on patients undergoing elective coronary bypass grafting to examine whether postoperative infusion of nifedipine (n = 25) could reduce the incidence of isolated transient myocardial ischemia, myocardial infarction, or both."	5.06	Infusion of nifedipine after coronary artery bypass grafting decreases the incidence of early postoperative myocardial ischemia. ( Binder, TM; Coraim, F; Holzinger, C; Huber, S; Peschl, F; Schwarzacher, S; Seitelberger, R; Spatt, J; Weber, H; Zwölfer, W, 1990)
"The use of metoprolol combined with nifedipine and diltiazem was studied and compared in 32 patients suffering from coronary disease associated with angina pectoris of effort."	5.06	[The use of metoprolol with calcium antagonists of different mechanisms of action (diltiazem and nifedipine) in patients with stenocardia of effort]. ( Guliev, AB; Lupanov, VP; Sidorenko, BA, 1990)
"The hemodynamic effects and antianginal efficacy of 10 mg amlodipine administered intravenously were assessed for 45 minutes in 18 subjects with stable angina pectoris."	5.06	Pharmacodynamics of amlodipine: hemodynamic effects and antianginal efficacy after atrial pacing. ( Grant, P; Gupta, S; Hillis, WS; Hogg, KJ; Hornung, RS; Singh, SP, 1989)
"The Nifedipine-Total Ischemia Awareness Program was designed to evaluate the prevalence, prognostic implications and effect of therapy on painful and painless myocardial ischemic episodes in a nationwide study of patients with angina pectoris."	5.06	The Nifedipine-Total Ischemia Awareness Program: a national survey of painful and painless myocardial ischemia including results of antiischemic therapy. ( Cohn, PF; Gerber, FR; Nesto, R; Vetrovec, GW, 1989)
"Although conventional treatment of angina pectoris with nifedipine capsules involves frequent daily dosing, a new vehicle for the once-daily delivery of this potent but insoluble calcium channel blocking agent has been developed."	5.06	Usefulness of nifedipine for myocardial ischemia and the nifedipine gastrointestinal therapeutic system. ( Bittar, N, 1989)
"The haemodynamic dose-response effects of a new long-acting slow-calcium channel blocking agent, amlodipine were evaluated in 20 patients with angiographically confirmed coronary heart disease."	5.06	A haemodynamic dose finding study with a new slow-calcium channel blocker (amlodipine) in coronary artery disease. ( Frais, MA; Jackson, NC; Reynolds, G; Sharma, SK; Silke, B; Taylor, SH; Verma, SP, 1986)
"In this single centre prospective, double blind study, 98 patients with suspected acute myocardial infarction (AMI) were randomized, within six hours, to nifedipine 10 mg (46 patients) or placebo (52 patients) both administered sublingually."	5.06	Effect of early treatment with nifedipine in suspected acute myocardial infarction. ( Branagan, JP; Collins, WC; Kelly, P; McCafferty, D; Walsh, K; Walsh, MJ, 1986)
"The short-term effect of oral nifedipine on effort tolerance was tested in 10 patients with effort angina pectoris and a positive effort test (GXT)."	5.06	Short-term effect of nifedipine on effort tolerance in patients with angina pectoris. ( Flugelman, MY; Gotsman, MS; Halon, DA; Shefer, A; Witt, H, 1986)
"In 12 male patients with angiographically confirmed coronary heart disease and stable angina the antianginal effects of 50 mg Gallopamil have been studied in comparison with 10 mg Nifedipine and placebo."	5.05	[Anti-angina effect of gallopamil in comparison with another calcium antagonist and a placebo]. ( Drews, H; Hopf, R; Kaltenbach, M, 1984)
"The effectiveness of verapamil in the management of patients with unstable angina pectoris associated with obstructive coronary artery disease was evaluated in 2 double-blind placebo-controlled randomized clinical trials."	5.05	Verapamil therapy for unstable angina pectoris: review of double-blind placebo-controlled randomized clinical trials. ( Conti, CR; Mehta, J, 1982)
"In 10 patients with angina pectoris and angiographically proven coronary heart disease, the effect of 60 mg of orally administered diltiazem (D) and 20 mg of nifedipine (N) on heart rate and exercise-induced ST-segment depression was investigated under randomized double-blind conditions."	5.05	[The effect of diltiazem and nifedipine on exercise-induced ST-segment depression and heart rate in patients with coronary heart disease (author's transl)]. ( Berlad, T; Hopf, R; Kaltenbach, M; Kober, G, 1981)
"In the first study the hemodynamic effects of standard doses of molsidomine (2 mg intravenously), isosorbide dinitrate (ISDN) (5 mg sublingually), and nifedipine (20 mg sublingually) were assessed at rest and under exercise conditions in a group of 30 patients with coronary heart disease."	5.05	Hemodynamic effects of molsidomine, isosorbide dinitrate, and nifedipine at rest and during exercise. ( Dougherty, C; Rutsch, W; Schartl, M; Schmutzler, H, 1985)
"The acute effects of nifedipine withdrawal were studied in 81 patients with angina at rest who had completed a prospective, double-blind, randomized trial of nifedipine versus placebo."	5.05	Safety of acute calcium antagonist withdrawal: studies in patients with unstable angina withdrawn from nifedipine. ( Gerstenblith, G; Gottlieb, SO, 1985)
"The haemodynamic effects of nifedipine, verapamil and diltiazem were measured and compared in an open randomized parallel investigation on 44 patients with coronary heart disease and compensated myocardial function."	5.05	[Differential therapy with calcium antagonists. Hemodynamic studies using nifedipine, verapamil and diltiazem]. ( Hochrein, H; Lehmann, HU, 1985)
"A single blind randomized parallel study designed to assess the anti-anginal efficacy of pindolol and nifedipine was carried out in 42 ambulatory coronary patients with stable angina pectoris."	5.04	Therapeutic effects of pindolol and nifedipine in patients with stable angina pectoris and asymptomatic resting ischemia. ( Amrein, R; Castagnoli, E; Chu, D; Cocco, G; Strozzi, C, 1979)
"In patients with coronary disease, the use of short-acting nifedipine in moderate to high doses causes an increase in total mortality."	4.79	Nifedipine. Dose-related increase in mortality in patients with coronary heart disease. ( Furberg, CD; Meyer, JV; Psaty, BM, 1995)
"Nifedipine antagonises influx of calcium through cell membrane slow channels, and sustained release formulations of the calcium channel blocker have been shown to be effective in the treatment of mild to moderate hypertension and both stable and variant angina pectoris."	4.78	Sustained release nifedipine formulations. An appraisal of their current uses and prospective roles in the treatment of hypertension, ischaemic heart disease and peripheral vascular disorders. ( Brogden, RN; Murdoch, D, 1991)
" Although nifedipine is highly effective against vasospastic angina, its use in threatened myocardial infarction or severe unstable angina is not supported by recent studies, unless combined with a beta-blocker."	4.77	Calcium channel antagonists. Part II: Use and comparative properties of the three prototypical calcium antagonists in ischemic heart disease, including recommendations based on an analysis of 41 trials. ( Opie, LH, 1988)
" In experimental animals, verapamil has been shown to reduce vulnerability to ventricular fibrillation during sympathetic stimulation and to prevent spontaneous fibrillation during both myocardial ischaemia and reperfusion."	4.77	Mechanisms involved in reperfusion arrhythmias. ( Hagestad, EL; Verrier, RL, 1986)
" Nifedipine and diltiazem are effective in the relief of angina, and verapamil is used in the treatment of supraventricular tachyarrhythmias."	4.77	Calcium channel blocking agents: physiologic basis of nursing intervention. ( Touloukian, JE, 1985)
" In chronic arterial hypertension, verapamil, and especially diltiazem seem to be superior to nifedipine."	4.76	Treatment of hypertension with calcium channel blockers: European data. ( Klein, WW, 1984)
" Nifedipine has proved effective in preventing coronary arterial spasm in patients with Prinzmetal's angina."	4.76	Inappropriate coronary vasoconstriction in patients with coronary artery disease: a role for nifedipine? ( Green, L; Grossman, W; Gunther, S; Mudge, GH; Muller, JE, 1979)
"The ACTION (A Coronary disease Trial Investigating Outcome with Nifedipine GITS) study was an independent, investigator-initiated, multi-national trial comparing nifedipine GITS to placebo in 7665 patients with stable angina pectoris."	3.74	Quality management of a large randomized double-blind multi-centre trial: the ACTION experience. ( Clayton, T; Danchin, N; de Brouwer, S; Kirwan, BA; Lubsen, J; Pocock, SJ; Poole-Wilson, PA; van Dalen, FJ, 2008)
" A recent study investigated the safety and efficacy of the calcium antagonist nifedipine GITS (gastro-intestinal therapeutic system) in patients with stable, but symptomatic coronary disease."	3.73	[ACTION: The clinical study of the month]. ( Piérard, LA, 2005)
"The effects of SMP-300, an orally active, potent, and selective Na+/H+ exchange inhibitor, were evaluated and compared with those of nifedipine, propranolol, and nicorandil on three experimental angina models and on myocardial infarction in rats."	3.71	Effect of an orally active Na+/H+ exchange inhibitor, SMP-300, on experimental angina and myocardial infarction models in rats. ( Matsui, K; Ohashi, N; Sasabe, M; Yamamoto, S, 2002)
" Although nifedipine-treated patients had a higher prevalence of coronary heart disease diagnosis than diuretic-treated patients (52% versus 35%), their relative risk of mortality was 0."	3.70	Mortality in the Jerusalem 70-year-olds longitudinal study: does nifedipine have a role? ( Bursztyn, M; Ginsberg, G; Maaravi, Y; Spilberg, O; Stessman, J, 1999)
"Effects of CD-832 on isoproterenol (ISO)-induced myocardial ischemia were studied in dogs with partial coronary stenosis of the left circumflex coronary artery and findings were compared with those for nifedipine or diltiazem."	3.69	Effects of a new calcium antagonist, CD-832, on isoproterenol-induced myocardial ischemia in dogs with partial coronary stenosis. ( Araki, H; Higuchi, S; Kishi-Tanikawa, S; Takahashi, K; Takahashi, T; Tsuchida, K, 1996)
"Acute effects of Nifedipine, a calcium channel blocking agent (CCBA), on central haemodynamics in patients with severe hypertension and angiographically proved coronary artery disease (CAD) has been studied using Nuclear Ventriculography (MUGA)."	3.68	Nuclear imaging study of nifedipine induced modulations of central haemodynamics in severe hypertension with and without coronary artery disease. ( Bhatia, ML; Jangid, DR; Kasliwal, RR; Trehan, N, 1993)
" With this end in mind, 21 patients with ischemic heart disease and arterial hypertension were divided into three groups of seven subjects each and submitted to different drug treatments with single daily doses: group 1 received isosorbide-5-mononitrate (60 mg), group 2 amlodipine (10 mg), and group 3 a combination of both drugs at the same dosage, for four weeks."	3.68	[The association of amlodipine with isosorbide-5-mononitrate in the treatment of ischemic-hypertensive cardiopathy]. ( D'Aprile, N; Faglia, S; Kristodhullo, A; Mondillo, S; Palazzuoli, V, 1992)
" In study 2 left ventricular function and ECGs were evaluated at rest and during exercise without any drug (control), with nitroglycerin, and with nifedipine in 21 patients with coronary disease (group I) and six normal subjects (group II)."	3.68	Clinical evaluation of cardiac function by ambulatory ventricular scintigraphic monitoring (VEST): validation and study of the effects of nitroglycerin and nifedipine in patients with and without coronary artery disease. ( Fudo, T; Kambara, H; Kawai, C; Mohiuddin, IH; Nohara, R; Ohkusa, T; Ohtani, H; Ono, S; Tamaki, N; Yonekura, Y, 1992)
" Dilzem (diltiazem) and cordaphene (nifedipine) were tested for their effects on the erythrocytic component of hemostasis, taking into account their capability of suppressing hemolysis, which made ADP, an important thrombocytic activator, enter the blood flow."	3.68	[Various aspects of the anti-aggregatory action of diltiazem and cordaphene in patients with ischemic heart disease]. ( Belousov, IuB; Leonova, MV; Rumiantsev, DO, 1991)
"In the present study, 20 patients with both hypertension and stabile angina pectoris were treated twice daily for 6 months with 50 mg atenolol and 20 mg retard-formulation nifedipine."	3.68	[Therapy of hypertensive coronary patients. Open long-term study with a combination of atenolol and nifedipine]. ( Lindner, UK, 1991)
"Haemodynamic effects of nifedipine (NIF) tablets were studied for 12 h in 10 patients with severe congestive heart failure due to ischaemic heart disease."	3.68	Haemodynamic effects of slow-release nifedipine in severe congestive heart failure due to ischaemic heart disease. ( Rossi, A; Ziacchi, V, 1990)
"In 22 of 27 cases of congestive heart failure (CHF) treated with nifedipine (NIF), significant improvements in resting hemodynamics were noticed."	3.68	Nifedipine pharmacodynamics and pharmacokinetics in treatment of congestive heart failure. ( Chen, DG; Chen, K; Feng, QP; Wang, ZQ, 1990)
"With this study including 9 patients with angiographically proven coronary heart disease it could be shown that a monotherapy with nifedipine in the galenic preparation as Adalat SL (Bayer AG, Leverkusen, FRG) is efficient in reducing myocardiac ischemia and concomitantly raising working capacity during bicycle ergometry as well after first time application of this drug as after continuous therapy with 1 tablet twice daily during 4 weeks."	3.68	[Modification of physical fitness of patients with coronary heart disease with nifedipine during a stay at altitude]. ( Deuber, HJ, 1990)
"The antiarrhythmic activity of the calcium entry blockers, verapamil, nifedipine and prenylamine, was assessed against arrhythmias occurring during 20 min of acute occlusion, or upon rapid reperfusion of the left anterior descending coronary artery (LAD) in anesthetized pigs."	3.67	Acute coronary artery occlusion-reperfusion arrhythmias in pigs: antiarrhythmic and antifibrillatory evaluation of verapamil, nifedipine, prenylamine and propranolol. ( Bergey, JL; McCallum, JD; Nocella, K; Wendt, RL, 1984)
"Nifedipine-induced gingival hyperplasia was first reported in 1984."	3.67	Nifedipine-induced gingival hyperplasia. ( Yusof, WZ, 1989)
"The effects of three calcium antagonists (diltiazem, verapamil, and nifedipine) on reperfusion-induced arrhythmias were compared in a conscious rat preparation with coronary artery occlusion and implanted electrocardiogram limb electrodes."	3.67	Reperfusion-induced arrhythmias in the conscious rat: a comparative study with three calcium antagonists. ( Braimbridge, MV; Hearse, DJ; Kinoshita, K; Manning, AS; Mitani, A, 1989)
"Combined nitrate/beta-blocker/nifedipine therapy is commonly used to treat refractory angina pectoris."	3.67	Nifedipine-induced hypotension and myocardial ischemia in refractory angina pectoris. ( Boden, WE; Bough, EW; Korr, KS, 1985)
"In twelve patients with coronary heart disease and hemodynamically significant coronary artery stenoses (LAD: 11, LAD plus RCA: 1) the effect of intracoronary nifedipine, 0."	3.67	Beneficial effects of intracoronary nifedipine during percutaneous transluminal coronary angioplasty. ( Behrenbeck, DW; Fuchs, M; Hilger, HH; Hombach, V; Höpp, HW; Tauchert, M, 1986)
" Among 15 patients with coronary artery disease who had been treated with nisoldipine, onset of severe unstable angina was observed in 2 and evolution of acute myocardial infarction in 1 patient after abrupt withdrawal of nisoldipine therapy."	3.67	Calcium-blocker withdrawal phenomenon: increase in affinity of alpha 2 adrenoceptors for agonist as a potential mechanism. ( Lopez, LM; Mehta, J, 1986)
"The comparative effects of the calcium-antagonists gallopamil and nifedipine on ischemia-induced and reperfusion-induced ventricular arrhythmias, particularly ventricular fibrillation (VF), were assessed in a total of 40 mongrel dogs in two experimental preparations."	3.67	Calcium antagonists and acute myocardial ischemia: comparative effects of gallopamil and nifedipine on ischemia-induced and reperfusion-induced ventricular arrhythmias, epicardial conduction times, and ventricular fibrillation thresholds. ( Bender, F; Gülker, H; Haverkamp, W; Hindricks, G, 1987)
" Nifedipine and DHM9 (carboxymethyl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate) were studied for their effects on arrhythmias resulting from regional myocardial ischaemia in conscious rats, and for their effects on left ventricular developed pressure in vitro."	3.67	The mechanism of action of calcium antagonists on arrhythmias in early myocardial ischaemia: studies with nifedipine and DHM9. ( Curtis, MJ; Walker, MJ, 1988)
"Acute nifedipine tests and courses of nifedipine treatment were conducted in 30 patients with essential hypertension."	3.67	[Effect of an acute pharmacological test and a course of treatment with nifedipine on cerebral hemodynamic indices and information processing efficiency in hypertension patients]. ( Liventseva, MM; Nechesova, TA; Pavlova, AI; Sidorenko, GI, 1988)
"Nifedipine (Adalat) was used in managing acute hypertension in 20 patients with coronary heart disease during endarterectomy for carotid stenosis."	3.67	[Treatment of hypertensive crises with nifedipine (Adalat) in patients at risk of infarct during interventions on the extracranial cerebral vessels]. ( Balzer, K; Fanoulas, G; Fidorra, K; Gresser, S; Müller, C, 1987)
"Pharmacokinetic, haemodynamic and radionuclide studies explored the acute pharmacokinetic and pharmacodynamic actions of nicardipine in patients with coronary heart disease."	3.67	Pharmacokinetic, haemodynamic and radionuclide studies with nicardipine in coronary artery disease. ( Finlayson, JR; Frais, MA; Graham, DJ; Reynolds, G; Silke, B; Taylor, SH; Verma, SP, 1986)
"To examine whether nicardipine, a dihydropyridine derivative, limits size of myocardial infarction, and to compare the protective effects of nicardipine administered before and early and late after coronary artery occlusion, 99mTc-labeled albumin microspheres were injected into the left atrium during 5 min temporary coronary artery occlusion to determine the extent of the hypoperfused zone (the area at risk)."	3.67	Comparative effects of nicardipine, a new calcium antagonist, on size of myocardial infarction after coronary artery occlusion in dogs. ( Endo, T; Fujita, S; Hayakawa, H; Iida, N; Kikuchi, K; Kiuchi, K; Nejima, J; Okumura, H, 1986)
"The systemic and coronary haemodynamic effects of felodipine were evaluated at rest and during stress induced atrial pacing in fourteen patients with chronic cardiac failure, secondary to coronary heart disease."	3.67	Felodipine in ventricular dysfunction. ( Hutton, I; Tweddel, AC, 1986)
"In conclusion, we observed first that nifedipine is highly efficacious in preventing the coronary vasospasm of Prinzmetal's variant angina."	3.66	Nifedipine therapy for coronary vasospasm. ( Antman, EM; Muller, JE; Stone, PH, 1983)
"We report clinical experience with the coronary vasodilator nifedipine in 127 patients with symptoms of myocardial ischemia associated with electrocardiographic or angiographic evidence, or both, of coronary-artery spasm."	3.66	Nifedipine therapy for coronary-artery spasm. Experience in 127 patients. ( Achuff, S; Antman, E; Braunwald, E; Geltman, E; Goldberg, S; Heupler, F; Kerin, NZ; Liang, CS; MacAlpin, R; Muller, J; Neff, RK; Reichek, N; Rubenfire, M; Tabatznik, B, 1980)
" During hospitalization all patients were treated with calcium antagonists (Nifedipine 10/20 mg every six hours) and/or nitrates (2% nitroglycerin ointment 2 inches every six/four hours) with one death (occurring after coronary arteriography) and eleven non-fatal myocardial infarctions."	3.66	[Angina at rest. Clinical, electrocardiographic and angiographic observations in 107 patients]. ( Ardissino, D; Bobba, P; Bramucci, E; Casali, PM; De Servi, S; Falcone, C; Martinelli, L; Minzioni, G; Mussini, A; Specchia, G; Viganò, M, 1980)
"Clinical experience with calcium antagonists in congestive heart failure has, to date, been mainly restricted to the use of nifedipine but there is either no or only a limited extent of information available on diltiazem and verapamil."	3.66	Calcium antagonists in heart failure. ( Camerini, F; Klugmann, S; Salvi, A, 1983)
"The effectiveness of nifedipine in treating angina pectoris at rest was evaluated in 14 patients with frequent ischemic episodes associated with S-T segment elevation or depression."	3.66	Treatment of angina at rest with nifedipine: a short-term controlled study. ( Bobba, P; Chimienti, M; Medici, A; Previtali, M; Ray, M; Salerno, JA; Specchia, G; Tavazzi, L, 1980)
"Nifedipine was evaluated in the management of eight patients with intractable coronary arterial spasm."	3.66	Nifedipine therapy for refractory coronary arterial spasm. ( Heupler, FA; Proudfit, WL, 1979)
"Nifedipine was administered in a dose of 30 mg orally to 14 patients with coronary heart disease and clinical evidence of left heart failure."	3.66	[The effect of nifedipine on the pulmonary artery pressure in patients with coronary heart disease (author's transl)]. ( Beck, OA; Hochrein, H, 1978)
"Nifedipine did not produce any effect on LV regional wall motion in group 1, but it induced significant changes in LV regional wall motion in seven patients in group 2."	2.68	Relation between exercise-induced left ventricular wall motion abnormalities and coronary artery disease in hypertensive patients: effects of blood pressure normalization. ( Berti, M; Maltagliati, A; Muratori, M; Passaretti, B; Pepi, M; Tamborini, G; Tavasci, E, 1997)
"To compare the negative inotropic effects of the four dihydropyridine-calcium-channel-blockers nifedipine (NIF), isradipine (ISR), nisoldipine (NIS) and felodipine (FEL) in man, the drugs were infused within 30 min intravenously in an equihypotensive dosage (NIF 2 mg, ISR 0."	2.67	[Comparison of the cardiodepressive effects of nifedipine, isradipine, nisoldipine and felodipine in patients with coronary heart disease]. ( Ickrath, O; Karsch, KR; Mauser, M; Voelker, W, 1993)
"The efficacy of amlodipine, a long half-life dihydropyridine calcium antagonist, at the dosage of 5-10 mg/day in a single daily administration, has been compared with that of nifedipine R, a short half-life dihydropyridine, at the dosage of 20-40 mg b."	2.67	Amlodipine versus nifedipine retard in the treatment of chronic ischemic heart disease. ( Cardillo, R; Castelli, D; Circo, A; Mangiameli, S; Platania, F; Scaccianoce, G, 1992)
"Isradipine is a more potent vasodilator than nifedipine at the same infusion rate."	2.67	Effect of isradipine on left ventricular relaxation and diastolic filling. ( Hess, OM; Hoppeler, H; Hug, R; Krayenbühl, HP; Turina, J, 1990)
"In 30 consecutive patients with Prinzmetal's angina pectoris, the antiischemic effect of felodipine, a new long-acting vasoselective calcium antagonist, administered at doses of 10 and 20 mg once daily was compared with that of the well-established therapeutic regimen with nifedipine administered at a dose of 20 mg 4 times daily."	2.67	Felodipine (once daily) versus nifedipine (four times daily) for Prinzmetal's angina pectoris. ( Ardissino, D; Barberis, P; Mussini, A; Rolla, A; Sardina, M; Savonitto, S; Specchia, G; Zanini, P, 1991)
"Nifedipine was ineffective, particularly in patients with angina predominantly on effort and with a moderate to severe reduction in exercise tolerance."	2.67	Transient myocardial ischemia during daily life in rest and exertional angina pectoris and comparison of effectiveness of metoprolol versus nifedipine. ( Ardissino, D; Egstrup, K; Feruglio, GA; Giordano, MP; Marraccini, P; Roncarolo, P; Rosenfeld, M; Savonitto, S; Slavich, G; Wahlqvist, I, 1991)
" Six patients had negative results; out of the remaining six, three exhibited a significant increase in the dosage required for provoking ischemia."	2.67	Intravenous nifedipine prevents ergonovine-induced myocardial ischemia in patients with stable effort angina. ( Brunelli, C; Caponnetto, S; Caudullo, M; Ghigliotti, G; Iannetti, M; Spallarossa, P, 1990)
" In this dosage peripheral effects--decrease of peripheral vascular resistance and mean aortic pressure--did not differ significantly between them."	2.67	[Myocardial effects of the calcium antagonists nifedipine, nisoldipine and isradipine in coronary heart disease]. ( Ickrath, O; Karsch, KR; Kühlkamp, V; Mauser, M; Voelker, W, 1990)
"In 50 patients with chronic congestive heart failure (CCHF, III or IV class), aged 62."	2.67	[Effect of vasodilator agents on the character and incidence of cardiac arrhythmia in chronic heart failure]. ( Bechler-Lisińska, J; Cholewa, M; Górski, L; Markiewicz, K, 1990)
"Nisoldipine is a new calcium channel blocker of the dihydropyridine family with a high affinity for coronary vessels."	2.66	Silent myocardial ischemia: improvement with nisoldipine therapy. ( Arce-Weston, B; Clark, PI; Glasser, SP, 1989)
"For effective treatment of coronary heart disease with calcium antagonists, knowledge of both the dose-response relationship of a remedy and equipotent dosage for comparison of different drugs is necessary."	2.66	[Dose-response relation of gallopamil in comparison with nifedipine, diltiazem and tiapamil in patients with coronary heart disease]. ( Fleischer, K; Forster, A; Hopf, R; Kaltenbach, M; Mohler, C; Schulz, PC, 1989)
" After a stable control period, dose-response curves were constructed for each drug with hemodynamics measured 10 minutes after intravenous boluses."	2.66	Comparative hemodynamic dose-response effects of five slow calcium channel-blocking agents in coronary artery disease. ( Frais, MA; Jackson, N; Midtbo, KA; Reynolds, G; Sharma, S; Silke, B; Taylor, SH; Verma, SP, 1987)
" Patients received 5 mg nifedipine three times a day rising to 20 mg three times a day in three dosage increments over six weeks or 2."	2.66	Comparison of isradipine and nifedipine in chronic stable angina. ( Handler, CE; Najm, Y; Rosenthal, E; Tsagadopoulos, D, 1988)
" The drugs were infused intravenously within 30 min in a dosage which led to a comparable afterload reduction (nifedipine [N] 2 mg, isradipine [I] 0."	2.66	[Isradipine (PN 200-110), a new dihydropyridine calcium antagonist with slight negative inotropic properties in comparison with nifedipine]. ( Karsch, KR; Mauser, M; Voelker, W, 1988)
"Nisoldipine is a newly developed calcium channel blocker with outstanding vasodilatory properties especially with regard to the coronary arteries."	2.66	The effects of nisoldipine on left ventricular filling rate in patients with ischemic heart disease measured with radionuclide gated blood pool scintigraphy. ( Flint, GR; Herbst, CP; Otto, AC; Sweetlove, MA; van Aswegen, A; Viviers, AC, 1988)
"Molsidomine was associated with a significant reduction of the left ventricular end-diastolic pressure and an increase in Vcf."	2.66	Preload or afterload reduction: which is more beneficial for patients with ischemic heart disease? ( Caralis, DG; Kyriakides, Z, 1988)
"Nitrendipine is a newly-developed calcium channel blocker derived from the dehydropyridine series which, according to experimental studies, affects marked dilation of the peripheral and coronary vessels."	2.66	[Antihypertensive and anti-ischemic effect of nitrendipine. Double-blind, randomized, crossover and placebo controlled acute study]. ( Blasini, R; Brügmann, U; Reiniger, G; Rudolph, W, 1985)
"Nifedipine was not better than placebo."	2.66	Atenolol and/or nifedipine in effort angina: which is the treatment of choice for exercise coronary protection? ( Caiazzo, MR; Carella, G; Chiariello, M; Condorelli, M; Cotecchia, MR; de Arcangelis, E; Di Maro, T; Romano, M, 1988)
" The required equally effective dosage was 0."	2.66	[Comparison of the acute hemodynamic effect of nisoldipine (Bay k 5552) and nifedipine in patients with ischemia-induced left ventricular impaired function]. ( Aschenberg, W; Bleifeld, W; Nienaber, C; Spielmann, R, 1988)
"Nisoldipine proved to be a potent calcium antagonist with slower onset and longer duration of action than nifedipine."	2.66	A comparison of the acute hemodynamic effects of nifedipine and nisoldipine in patients with ischemic reduced left ventricular function. ( Herbst, CP; Otto, AC; Strugo, V; Sweetlove, A; van Aswegen, A, 1987)
"nifedipine were administered."	2.66	[Change in the diameter of the coronary vessels following sublingual or intravenous nifedipine administration correlated with the plasma level]. ( Daniel, W; Hecker, H; Jost, S; Lichtlen, PR; Nellessen, U; Rafflenbeul, W, 1987)
" The absence of reflex tachycardia found in previous chronic oral dosing studies with this drug appears to take some days to develop in humans."	2.66	PY 108-068--acute effects of a single oral dose in chronic stable angina. ( de Buitleir, M; Krikler, DM; Krikler, S, 1986)
" Chronic oral administration of nifedipine in combination with atenolol precipitated LV failure only in those with the lowest EF and highest LVEDP; usually LV failure was present with atenolol alone."	2.66	Hemodynamic effects of nifedipine given alone and in combination with atenolol in patients with impaired left ventricular function. ( de Buitleir, M; Krikler, DM; Rowland, E, 1985)
"Nifedipine is a calcium antagonist with established anti-vasospastic action in man and, possibly cardioprotective effects during ischaemia."	2.65	Acute myocardial ischaemia: what information can be expected in the near future from ongoing clinical trials with nifedipine? ( Hugenholtz, PG; Lubsen, J, 1983)
"In 28 patients with unstable angina pectoris biplane coronary angiography was performed in the acute stage."	2.65	[Dynamics of critical stenosis in patients with unstable angina pectoris]. ( Karsch, KR; Niemczyk, P; Seipel, L; Voelker, W, 1984)
"Calcium antagonists are used in the treatment of hypertension and angina."	2.44	The ACTION study: nifedipine in patients with symptomatic stable angina and hypertension. ( Coca, A; Sierra, C, 2008)
" However, the short-acting formulations of nifedipine had pharmacokinetic properties that were far from ideal and in 1995, several studies involving various dosing regimens reported possible dangerous effects in secondary prevention."	2.44	Nifedipine Gastrointestinal Therapeutic System (GITS) in the treatment of coronary heart disease and hypertension. ( Dunselman, PH; Kragten, JA, 2007)
"Felodipine is a highly vascular selective calcium entry blocker, with a vascular selectivity ratio greater than 100, as shown experimentally."	2.39	Vascular selective calcium entry blockers in the treatment of cardiovascular disorders: focus on felodipine. ( Cheng, CP; Elvelin, L; Little, WC; Nordlander, M, 1995)
"Verapamil pretreatment produced a similarly selective dilatation of larger coronary arterioles and protected against the ischaemia-induced fall in capillary red cell content."	2.38	Calcium antagonists and myocardial microperfusion. ( Köbler, W; Möller, P; Neumann, FJ; Parekh, N; Steinhausen, M; Tillmanns, H; Waas, W; Zimmermann, R, 1991)
"With verapamil there is a small tendency for a reduction in reinfarction, with nifedipine a clear worsening, and with diltiazem a reduction almost reaching statistical significance."	2.38	Protective effects of calcium antagonists against ischaemia and reperfusion damage. ( Ferrari, R; Visioli, O, 1991)
"Amlodipine is a dihydropyridine calcium antagonist that has unique pharmacokinetic properties."	2.38	The efficacy of amlodipine in the management of ischaemic heart disease. ( McGibney, D, 1991)
"Treatment with amlodipine was found to reduce myocardial oxygen demand, improve recovery of peak developed tension, have a favourable effect on Ca2+ fluxes, improve retention of tissue adenosine triphosphate and creatine phosphate, and reduce acidosis in the ischaemic/reperfused myocardium."	2.38	The pharmacological profile of amlodipine in relation to ischaemic heart disease. ( Burges, RA, 1991)
"Amlodipine was found to increase exercise capacity significantly and reduce electrocardiographic evidence of myocardial ischaemia after treadmill exercise testing 24 h after administration compared with placebo in patients suffering from angina pectoris."	2.38	A review of amlodipine in myocardial ischaemia. ( Taylor, SH, 1991)
"Felodipine was equally effective as nifedipine in preventing an alpha 2-adrenoceptor-mediated increase in coronary resistance and the resulting contractile dysfunction distal to severe coronary stenoses."	2.38	Prevention of alpha-adrenergic coronary constriction by calcium-antagonists. ( Deussen, A; Guth, BD; Heusch, G, 1990)
"Amlodipine has also been found to be effective in reducing the anginal attack rate in patients with vasospastic angina."	2.38	The efficacy of amlodipine in myocardial ischemia. ( Taylor, SH, 1989)
"When nifedipine was compared with isosorbide dinitrate in a randomized crossover, double-blind trial in patients with coronary artery spasm, both drugs were shown to be efficacious and neither was superior."	2.37	Large vessel coronary vasospasm: diagnosis, natural history and treatment. ( Conti, CR, 1985)
"Unstable angina is a common ischemic syndrome that is characterized by chest pain occurring at rest often with transient ischemic electrocardiographic changes."	2.37	Assessing the total ischemic burden in the management of unstable angina. A review. ( Gerstenblith, G; Gottlieb, SO, 1986)
"Pretreatment with verapamil reduced the size of these subendocardial infarcts from 34 +/- 8 to 8 +/- 3% of the ischemic circumflex vascular bed (anatomic area at risk)."	2.37	Effects of calcium-channel blockers on myocardial preservation during experimental acute myocardial infarction. ( Jennings, RB; Reimer, KA, 1985)
"Cardiogenic shock is associated with primary myocardial failure and a low-flow state."	2.36	Calcium entry blockers: potential applications in shock. ( Greenfield, LJ; Hess, ML, 1983)
"Of 246 incident cancer cases, 129 occurred among the users (2."	1.30	Calcium channel blocking agents and risk of cancer in patients with coronary heart disease. Benzafibrate Infarction Prevention (BIP) Study Research Group. ( Behar, S; Boyko, V; Braun, S; Goldbourt, U; Kaplinsky, E; Laniado, S; Reicher-Reiss, H, 1998)
" For both drug classes, we suggest that long-acting agents be considered, providing therapeutic coverage well beyond the normal dosing interval."	1.29	1,4-Dihydropyridines versus beta-blockers for hypertension: are either safe for the heart? ( Leenen, FH, 1996)
"Hypertension is a known risk factor in the genesis of coronary artery disease."	1.28	Influence of mild to moderate treated hypertension on 9-11 year mortality in patients with pre-existing coronary heart disease. ( Gupta, KD; Gupta, R; Kasliwal, P, 1992)
"4."	1.28	Impaired endothelium-dependent relaxation of dog coronary arteries after myocardial ischaemia and reperfusion: prevention by amlodipine, propranolol and allopurinol. ( Dalipram, RA; Dusting, GJ; Sobey, CG; Woodman, OL, 1992)
"Amlodipine is a long-acting dihydropyridine calcium antagonist with vascular selectivity."	1.28	Vascular and myocardial effects of amlodipine: an overview. ( Gu, XH; Nayler, WG, 1991)
"Pretreatment with nifedipine (3 x 10(-8) M) prevented the rise in LVEDP induced by pacing tachycardia."	1.28	Effects of nifedipine on diastolic abnormalities in low-flow and pacing-induced ischemia in isolated rat hearts. ( Iizuka, M; Ikenouchi, H; Momomura, S; Serizawa, T; Sugimoto, T, 1991)
"Nifedipine pretreatment prevented the early cocaine-induced decrease in coronary blood flow and improved left ventricular dP/dt compared with untreated control animals."	1.28	Nifedipine protects the heart from the acute deleterious effects of cocaine if administered before but not after cocaine. ( Alker, KJ; Eisenhauer, AC; Hale, SL; Kloner, RA; Rezkalla, SH, 1991)
"Pretreatment with nifedipine inhibited the maximum contraction induced by endothelin, but did not affect the threshold dose or the half maximal effective dose (ED50)."	1.28	Myocardial ischaemia induced by endothelin in the intact rabbit: angiographic analysis. ( Akita, H; Fukuzaki, H; Hirata, K; Matsuda, Y; Yokoyama, M, 1990)
"Amlodipine is a long-acting dihydropyridine-based Ca2+ channel blocker, developed for use on a once-daily basis."	1.28	Amlodipine pretreatment and the ischemic heart. ( Nayler, WG, 1989)
"Isradipine is a new dihydropyridine calcium antagonist with myocardial effects significantly different from those of nifedipine, as shown by in vitro and animal experimental data."	1.28	Myocardial properties of the new dihydropyridine calcium antagonist isradipine compared to nifedipine with or without additional beta blockade in coronary artery disease. ( Ickrath, O; Karsch, KR; Mauser, M; Voelker, W, 1989)
"Nifedipine is an effective agent in acute hypertensive episodes, even in patients receiving chronic calcium-channel blocker therapy."	1.28	Nifedipine in the treatment of hypertensive episodes in the coronary care unit. ( Hilleman, DE; Malesker, MA; Mohiuddin, SM; Mooss, AN; Rovang, KS; Sketch, MH, 1989)
" In order to compare the pharmacokinetic properties of these compounds the dilation of the 'normal' coronary segments was correlated with the respective drug plasma levels; maximal plasma concentrations averaged 62 +/- 21 ng ml-1 (7th min) in group I and 17 +/- 7 ng ml-1 (4th min) in group II respectively."	1.28	Coronary vasodilation with dihydropyridines--a pharmacokinetic study. ( Bossaller, C; Hecker, H; Jost, S; Lichtlen, PR; Lippolt, P; Mogwitz, B; Nellessen, U; Rafflenbeul, W; Zwicky, P, 1989)
"Nifedipine was effective in reducing the frequency and duration of SMI in our patients."	1.28	[Clinical characteristics of silent myocardial ischemia and the effect of nifedipine treatment]. ( Huang, L; Xin, Q; Zhu, SJ, 1989)
"Verapamil-treated dogs showed higher pH of ischemic subendocardium after 15 min ischemia (6."	1.28	Contrasting effects of verapamil and nifedipine on pH of ischemic myocardium in the dog. ( Aamodt, R; Epstein, SE; Goldstein, SR; Greene, R; Markle, DR; Patterson, RE; Ro, YM; Speir, E; Steadman, K, 1989)
"Nifedipine is a strong calcium antagonist; it blocks the excitation-contraction coupling, yet at therapeutic dosage levels it has few side effects."	1.27	What is preferable in unstable angina, beta-blockade or calcium-inhibition? ( Hugenholtz, PG; Serruys, PW; Simoons, ML, 1983)
"The mean degree of stenosis was reduced from 77 +/- 12% to 29 +/- 15% and the mean systolic pressure gradient from 78 +/- 18 to 25 +/- 9 mmHg."	1.27	Role of percutaneous transluminal coronary angioplasty in patients with variant angina and coexistent coronary stenosis refractory to maximal medical therapy. ( Brücke, P; Herbinger, W; Leisch, F, 1984)
" Thus at the dosage used felodipine was a potent dilator of systemic arterioles but had no direct effect on left ventricular function."	1.27	Acute haemodynamic effects of felodipine during beta blockade in patients with coronary artery disease. ( Culling, W; Ruttley, MS; Sheridan, DJ, 1984)
"The haemodynamic dose-response effects of the slow channel blocking agent nicardipine were evaluated in 10 male patients with angiographically confirmed coronary artery disease."	1.27	Haemodynamic dose-response effects of i.v. nicardipine in coronary artery disease. ( Hussain, M; Nelson, GI; Silke, B; Taylor, SH; Verma, SP, 1984)
"Twenty-six patients had no ventricular arrhythmias in 633 ischemic attacks; 16 patients had ventricular arrhythmias in 116/586 ischemic attacks."	1.27	[Characterization and therapy of ventricular arrhythmias due to transient myocardial ischemic attacks in variant angina]. ( Dini, P; Prati, PL; Rocca, P; Turitto, G; Vicari, M; Zanchi, E, 1984)
"Nicardipine is a potent vasodilator, which produced a marked reduction of systemic vascular resistance and left ventricular end-diastolic pressure during exercise."	1.27	Immediate and longer-term effects of nicardipine, at rest and during exercise, in patients with coronary artery disease. ( Jaarsma, W; Kan, G; Lie, KI; Visser, CA, 1984)
"nicardipine was given to 9 patients with coronary artery disease, pretreated with propranolol (0."	1.27	Effects of nicardipine or nifedipine added to propranolol in patients with coronary artery disease. ( Brasseur, LA; Charlier, AA; Etienne, J; Pouleur, H; Rousseau, MF; Van Eyll, C; Van Mechelen, H, 1984)
"The number of reperfusion arrhythmias was also significantly lower in the treated animals."	1.27	Nifedipine with and without propranolol in the treatment of myocardial ischemia: effect on ventricular arrhythmias and recovery of regional wall function. ( ten Cate, FJ; Verdouw, PD; Wolffenbuttel, BH, 1983)
"Verapamil was more active than nifedipine in both models."	1.27	Evaluation of cardiac anoxia and ischemia models in the rat using calcium antagonists. ( Jacobs, LW; Rosenberger, LB; Stanton, HC, 1984)
" These differences were significant at all methacholine dosage levels by paired t test except for FEV1 at the 3."	1.27	Inhibition of airway reactivity by nifedipine in patients with coronary artery disease. ( Akers, S; Bloom, K; Gonzalez, JM; Morice, RC; Raizner, AE; Stevens, PM, 1983)
"Nifedipine was added to the reservoir and 0."	1.27	The protective effects of nifedipine in the isolated cat heart. ( Lefer, AM; Okamatsu, S, 1983)
"With nifedipine treatment, LAD flow (flow probe) was increased 44% as compared with the initial occluded value, with most of this increase going to the subepicardium (microspheres)."	1.27	Effect of nifedipine on regional O2 consumption in ischemic myocardial tissue. ( Grover, GJ; Mackenzie, JW; Scholz, P; Weiss, HR, 1988)
"Amlodipine is a long-acting dihydropyridine-based calcium antagonist developed for use on a once-a-day basis."	1.27	The effect of amlodipine on hypertension-induced cardiac hypertrophy and reperfusion-induced calcium overload. ( Nayler, WG, 1988)
"With nifedipine treatment, diastolic function improved, with a decrease in the time to peak filling rate (PFR) at rest (from 174 +/- 34 to 152 +/- 31 ms, p less than 0."	1.27	Addition of nifedipine to maximal nitrate and beta-adrenoreceptor blocker therapy in coronary artery disease. ( Antman, EM; Holman, BL; Nesto, RW; Polak, JF; White, HD; Wynne, J, 1985)
"Nicardipine is a powerful arteriodilator without detectable negative inotropic effects and prolongs the time to pacing induced angina."	1.27	Effect of nicardipine on left ventricular function and on angina induced by atrial pacing in patients with coronary artery disease. ( Lipkin, DP; Poole-Wilson, PA, 1985)
"Nifedipine has not been observed to cause significant left ventricular depression in patients with angina pectoris; this is primarily due to peripheral arteriolar vasodilatation, which reduces impedance of left ventricular ejection."	1.27	Effect of nifedipine on left ventricular function in patients with angina pectoris. ( Nesto, R; White, H, 1986)
"Nifedipine therapy was associated with an improved LV filling in nearly all cases of HCM and HHD, and in some cases of IHD."	1.27	[Stress pulsed Doppler echocardiography in the evaluation of diastolic left ventricular function]. ( Asai, M; Fukuda, N; Ishimoto, T; Mori, H; Niki, T; Ohkushi, H; Oki, T; Taoka, M; Tominaga, T, 1985)
"Combinations of antianginal drugs may be used for an additive effect against angina, but also to off-set unwanted effects of one drug with another, either by direct effects or by a reduction of dosage of each drug."	1.27	Interactions of vasodilators with calcium entry- and beta-blockers in patients with coronary heart disease. ( Adam, WE; Haerer, W; Henze, E; Hermann, T; Kohler, J; Kress, P; Stauch, M, 1986)
"Nitroglycerin and lower doses of nifedipine and prostacyclin improved coronary perfusion due to selective or preferential dilation of large coronary arteries."	1.27	Comparative effects of intracoronary vasodilators on restoring coronary perfusion during flow-reducing coronary stenosis in the dog. ( Fukuzaki, H; Kashiki, M; Sakamoto, S; Yokoyama, M, 1987)
"When nisoldipine was included 10 min before ischemia, during ischemia (33 min) and reperfusion (30 min), however, the recovery of cardiac function and tissue ATP levels was significantly increased."	1.27	A low concentration of nisoldipine reduces ischemic heart injury: enhanced reflow and recovery of contractile function without energy preservation during ischemia. ( Hatley, AA; Watts, JA; Whipple, JP, 1987)
" Twelve patients were not receiving therapy or were receiving very low dosage therapy, including 8 with asymptomatic periods of more than 1 year."	1.27	Late follow-up (41 to 102 months) of medically treated patients with coronary artery spasm and minor atherosclerotic coronary obstructions. ( Alwyn, M; Freedman, SB; Kelly, DT; Richmond, DR, 1986)
"Nicardipine was administered as a 2 mg bolus (i."	1.27	Effects of nicardipine on left ventricular function and energetics in man. ( Feldman, RL; Hill, JA; Lambert, CR; Pepine, CJ, 1986)
"Nifedipine was given bucally in a dose (10 or 20 mg) that decreased aortic pressure 5 mm Hg or more."	1.27	Effect of nifedipine on coronary hemodynamics in patients with left anterior descending coronary occlusion. ( Conti, CR; Feldman, RL; Hill, JA; Pepine, CJ, 1985)
"Diltiazem was not significantly different from placebo."	1.27	Comparative effects of calcium-channel blocking agents on left ventricular function during acute ischemia in dogs with and without congestive heart failure. ( Epstein, SE; Patterson, RE; Urquhart, J, 1985)
"In the absence of coronary stenosis, intracoronary infusion of ergonovine (0."	1.27	Myocardial ischaemia produced by ergonovine-induced vasoconstriction during preexisting coronary stenosis: experimental conditions for the geometric theory. ( Fukuzaki, H; Kawashima, S; Okada, T; Sakamoto, S; Yokoyama, M, 1985)
"Pretreatment with aspirin (6 mg/kg i."	1.27	Cardiac sympathetic nerve activity and progressive vasoconstriction distal to coronary stenoses: feed-back aggravation of myocardial ischemia. ( Deussen, A; Heusch, G; Thämer, V, 1985)
"When nifedipine was administered during the occlusion, recovery after a 2 minute occlusion was accelerated slightly to 10 to 15 minutes."	1.27	Comparative echocardiographic study of recovery of diastolic versus systolic function after brief periods of coronary occlusion: differential effects of intravenous nifedipine administered before and during occlusion. ( Chang, BL; Corday, E; Fujibayashi, Y; Meerbaum, S; Rajagopalan, RE; Yamazaki, S, 1985)
"When nicardipine (0."	1.27	Effects of nicardipine on ischemic mechanical failure and tissue injury in isolated perfused rat heart. ( Noshiro, O; Ohhata, I; Ohta, A; Shikama, H, 1985)
" In 10 patients resting cardiac stroke output (thermodilution) and pulmonary artery occluded pressure were determined following four intravenous nisoldipine injections (cumulative dosage of 1, 2, 4 and 8 micrograms kg-1)."	1.27	Haemodynamic dose-response effects of intravenous nisoldipine in coronary artery disease. ( Frais, MA; Muller, P; Reynolds, G; Silke, B; Taylor, SH; Verma, SP, 1985)
"Coronary spasm is due to strong contraction of coronary vascular smooth muscle cells which is triggered by an increase of intracellular calcium ions; hyperventilation plus TRIS-buffer infusion induces coronary spasm by decreasing hydrogen ions which antagonize the action of calcium ions."	1.26	Pathophysiology and treatment of coronary arterial spasm. ( Yasue, H, 1980)
"Nifedipine was found to be valuable in stabilizing unstable angina persisting despite beta-blockade and nitrates."	1.26	Benefits from adding nifedipine to the treatment of unstable angina when beta-blockade and isosorbide dinitrate have proved inadequate. ( Hagemeijer, F; Santoso, T; van Mechelen, R, 1982)
"Niludipine was at 93."	1.26	Clinical effectiveness of niludipine in patients with ischemic heart disease. ( Ban, M; Hashimoto, H; Imura, K; Ito, T; Kanayama, H; Kotaka, K; Miyazaki, Y; Mochizuki, M; Nizoe, K; Ogawa, K; Okumura, K; Sakai, K; Shikano, M; Sone, T; Uno, T; Watanabe, J, 1982)
"Nifedipine probably has a similar action, but data supporting this view are limited."	1.26	Nifedipine reduces adenine nucleotide breakdown in ischemic rat heart. ( De Jong, JW; De Tombe, PP; Harmsen, E; Keijzer, E, 1982)
"Nifedipine was 4 times as potent as FR 7534."	1.26	Comparison of two dihydropyridine calcium antagonists on coronary collateral blood flow in acute myocardial ischemia. ( Gross, GJ; Hardman, HF; Jolly, SR, 1981)
"Thus nifedipine appears to be an efficacious agent in the treatment of refractory rest angina in patients with obstructive coronary artery disease."	1.26	Efficacy of nifedipine in rest angina refractory to propranolol and nitrates in patients with obstructive coronary artery disease. ( Banka, VS; Bodenheimer, MM; Feldman, M; Helfant, RH; Moses, JW; Wertheimer, JH, 1981)
"Nifedipine has been suggested to have more potent slow channel blocking action than other agents of this type."	1.26	Effects of nifedipine on conduction delay during ventricular myocardial ischemia and reperfusion. ( Fujimoto, T; Hamamoto, H; Mandel, WJ; McCullen, AE; Peter, T, 1981)
"The hypotensive effect of nifedipine (a Ca2+-antagonist) was studied in acute tests and during the long-term administration of the drug together with propranolol."	1.26	Hypotensive action of nifedipine (Ca2+-antagonist) and propranolol in acute trials and its long-term therapy of hypertensive coronary heart disease patients. ( Aoki, K; Kato, K; Kawaguchi, Y; Kondo, S; Mochizuki, A; Sato, K; Yamamoto, M, 1981)
" Dosage of all drugs was adjusted to reduce mean aortic pressure by no more than 5 mmHg."	1.26	Improved performance of ischemic canine myocardium in response to nifedipine and diltiazem. ( Henry, PD; Pérez, JE; Sobel, BE, 1980)
"Nifedipine was found effective in protecting myocardial performance and structure after 2 hours of global ischemia during hypothermic cardiopulmonary bypass."	1.26	Nifedipine: a myocardial protective agent. ( Christlieb, IY; Clark, RE; Fischer, AE; Henry, PD; Nora, JD; Sobel, BE; Williamson, JR, 1979)

Timeframe	Studies, this research(%)	All Research%
pre-1990	535 (72.99)	18.7374
1990's	178 (24.28)	18.2507
2000's	18 (2.46)	29.6817
2010's	2 (0.27)	24.3611
2020's	0 (0.00)	2.80

Trial	Phase	Enrollment	Study Type	Start Date	Status
Comparism Between Efficacy and Effectiveness Between Slow Infusion of Calcium Channel Blockers and Intravenous Bolus Adenosine in the Management of Supraventricular Tachycardia in the Emergency Department.[NCT00413712]	Phase 4	206 participants	Interventional	1997-01-31	Completed
[NCT00000478]	Phase 3	0 participants	Interventional	1990-11-30	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
The ACTION study: nifedipine in patients with symptomatic stable angina and hypertension. Expert review of cardiovascular therapy, 2008, Volume: 6, Issue:8 Topics: Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Comorbidity; Cor	2008
Nifedipine Gastrointestinal Therapeutic System (GITS) in the treatment of coronary heart disease and hypertension. Expert review of cardiovascular therapy, 2007, Volume: 5, Issue:4 Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Coronary Disease; Cost Savings; D	2007
[ACTION study: efficacy of nifedipine in preventing cardiovascular disease in patients with coronary artery disease]. Drugs, 2006, Volume: 66 Spec No 1 Topics: Calcium Channel Blockers; Cardiovascular Diseases; Coronary Disease; Coronary Vessels; Double-Blind	2006
[JMIC-B study and its sub-analyses: effect of nifedipine in Japanese hypertensive patients with coronary artery disease]. Drugs, 2006, Volume: 66 Spec No 1 Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Coronary Disease; Humans; Hyperte	2006
Calcium channel blockers as antihypertensive agents. The American journal of medicine, 1984, Oct-05, Volume: 77, Issue:4A Topics: Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Clinical Trials as Topic; Coronary Disease;	1984
Prevention of cardiogenic shock. American heart journal, 1980, Volume: 99, Issue:2 Topics: Adrenergic beta-Antagonists; Coronary Disease; Creatine Kinase; Echocardiography; Electrocardiograph	1980
Combined therapy with beta-adrenergic blockers and calcium-antagonists in patients with ischemic heart disease. Herz, 1982, Volume: 7, Issue:4 Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Coronary Disease; Drug Thera	1982
[Use of calcium antagonists in the therapy of coronary heart disease]. Der Internist, 1983, Volume: 24, Issue:7 Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium; Coronary Disease; Diltiazem; Drug Therapy, Co	1983
Clinical applications of slow channel blocking compounds. Pharmacology & therapeutics, 1983, Volume: 23, Issue:1 Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Blood Platelets; Blood Vessels; Calcium	1983
[Unstable angina pectoris and pre-infarct syndrome]. Der Internist, 1983, Volume: 24, Issue:7 Topics: Angina Pectoris, Variant; Angioplasty, Balloon; Coronary Angiography; Coronary Disease; Coronary Vas	1983
Calcium antagonists and their potential role in the prevention of sudden coronary death. Annals of the New York Academy of Sciences, 1982, Volume: 382 Topics: Action Potentials; Animals; Atrial Fibrillation; Atrial Flutter; Atrioventricular Node; Calcium Chan	1982
Calcium antagonists in the treatment of individuals with ischemic heart disease. Angiology, 1982, Volume: 33, Issue:8 Topics: Angina Pectoris; Angina Pectoris, Variant; Calcium; Calcium Channel Blockers; Coronary Disease; Dilt	1982
Mechanism of action of calcium-channel-blocking agents. The New England journal of medicine, 1982, Dec-23, Volume: 307, Issue:26 Topics: Action Potentials; Angina Pectoris; Arrhythmias, Cardiac; Blood Vessels; Calcium; Calcium Channel Bl	1982
[Calcium antagonists in cardiology]. La Clinica terapeutica, 1983, Jan-15, Volume: 104, Issue:1 Topics: Arrhythmias, Cardiac; Calcium Channel Blockers; Cardiomyopathy, Hypertrophic; Coronary Disease; Dilt	1983
Calcium entry blockers: potential applications in shock. Advances in shock research, 1983, Volume: 10 Topics: Animals; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Coronary Disease; Diltiazem; Dogs	1983
Nifedipine for angina and acute myocardial ischaemia. Postgraduate medical journal, 1983, Volume: 59 Suppl 2 Topics: Acute Disease; Angina Pectoris; Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Di	1983
Calcium and cell death. European heart journal, 1983, Volume: 4 Suppl C Topics: Adenosine Triphosphate; Animals; Calcium; Cell Survival; Coronary Disease; Heart Arrest, Induced; Hu	1983
[Calcium antagonists. Properties and current indications]. Recenti progressi in medicina, 1984, Volume: 75, Issue:4 Topics: Arrhythmias, Cardiac; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Diltiaze	1984
Treatment of hypertension with calcium channel blockers: European data. The American journal of medicine, 1984, Oct-05, Volume: 77, Issue:4A Topics: Age Factors; Blood Pressure; Calcium Channel Blockers; Coronary Disease; Diltiazem; Europe; Humans;	1984
Hypertensive crisis. Cardiology clinics, 1984, Volume: 2, Issue:2 Topics: Antihypertensive Agents; Brain Diseases; Cerebrovascular Disorders; Clonidine; Coronary Disease; Dia	1984
Microcirculatory actions and uses of naturally-occurring (magnesium) and novel synthetic calcium channel blockers. Microcirculation, endothelium, and lymphatics, 1984, Volume: 1, Issue:2 Topics: Anesthesia; Animals; Arterioles; Blood Pressure; Calcium; Calcium Channel Blockers; Cell Membrane Pe	1984
[Treatment of angina pectoris with calcium antagonists]. Herz, 1982, Volume: 7, Issue:4 Topics: Angina Pectoris; Calcium Channel Blockers; Coronary Disease; Diltiazem; Drug Therapy, Combination; E	1982
Calcium entry blockers: uses and implications for anesthesiologists. Anesthesiology, 1982, Volume: 57, Issue:6 Topics: Anesthesia, General; Animals; Arrhythmias, Cardiac; Biotransformation; Calcium Channel Blockers; Cor	1982
[Indications for use of calcium antagonists]. Medizinische Klinik, 1980, Apr-11, Volume: 75, Issue:8 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium; Cardiotonic Agents; Coronary Disease	1980
Nifedipine. Dose-related increase in mortality in patients with coronary heart disease. Circulation, 1995, Sep-01, Volume: 92, Issue:5 Topics: Angina Pectoris; Arrhythmias, Cardiac; Calcium Channel Blockers; Confidence Intervals; Coronary Dise	1995
Vascular selective calcium entry blockers in the treatment of cardiovascular disorders: focus on felodipine. Cardiovascular drugs and therapy, 1995, Volume: 9, Issue:5 Topics: Amlodipine; Calcium Channel Blockers; Coronary Disease; Felodipine; Heart Failure; Hemodynamics; Hum	1995
The effects of calcium antagonists after PTCA. European heart journal, 1995, Volume: 16 Suppl H Topics: Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Clinical Trials as Topic; Constriction, Pa	1995
The value of nifedipine in the treatment of hypertension, coronary heart disease and myocardial infarction (post-infarction therapy). Current medical research and opinion, 1996, Volume: 13, Issue:7 Topics: Adult; Aged; Calcium Channel Blockers; Coronary Disease; Female; Germany; Humans; Hypertension; Male	1996
Nifedipine in acute coronary syndromes: Furberg's refrain revisited. European heart journal, 1996, Volume: 17, Issue:8 Topics: Acute Disease; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Dose-Response R	1996
Critical appraisal of recent studies on nifedipine and other calcium channel blockers in coronary artery disease and hypertension. European heart journal, 1996, Volume: 17, Issue:8 Topics: Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Humans; Hypertension; Meta-Ana	1996
Anti-atherosclerotic properties of nifedipine. Benefit of early intervention to prevent cardiovascular complications. Cardiology, 1997, Volume: 88 Suppl 3 Topics: Acute Disease; Animals; Arteriosclerosis; Calcium; Calcium Channel Blockers; Coronary Angiography; C	1997
[Exercise hemodynamic in hypertension associated with coronary microangiopathy, coronary heart disease and without ischemic syndrome effect of nifedipine]. Zeitschrift fur Kardiologie, 1997, Volume: 86, Issue:11 Topics: Coronary Disease; Echocardiography; Ergometry; Female; Heart Function Tests; Hemodynamics; Humans; H	1997
[Controversy about using calcium antagonists for treatment of coronary disease and hypertension]. Przeglad lekarski, 1997, Volume: 54, Issue:9 Topics: Calcium Channel Blockers; Cerebrovascular Disorders; Clinical Trials as Topic; Coronary Disease; Hum	1997
The patient with hypertension. Quintessence international (Berlin, Germany : 1985), 2001, Volume: 32, Issue:9 Topics: Anesthesia, Dental; Calcium Channel Blockers; Coronary Disease; Dental Care for Chronically Ill; Eme	2001
[Biochemical mechanisms of action of coronarodilating agents (review of the literature)]. Vrachebnoe delo, 1976, Issue:5 Topics: Adrenergic beta-Antagonists; Aminophylline; Animals; Chromonar; Coronary Disease; Coronary Vessels;	1976
[Calcium antagonists in cardiology]. Bollettino della Societa italiana di cardiologia, 1978, Issue:1 Suppl Topics: Adrenergic beta-Antagonists; Angina Pectoris; Arrhythmias, Cardiac; Calcium; Coronary Disease; Human	1978
Clinical aspects of Ca-blocking agents. Acta pharmacologica et toxicologica, 1978, Volume: 43 Suppl 1 Topics: Angina Pectoris; Animals; Arrhythmias, Cardiac; Calcium; Coronary Disease; Cricetinae; Humans; Hyper	1978
Inappropriate coronary vasoconstriction in patients with coronary artery disease: a role for nifedipine? The American journal of cardiology, 1979, Oct-22, Volume: 44, Issue:5 Topics: Angina Pectoris, Variant; Blood Pressure; Cardiac Catheterization; Cardiac Pacing, Artificial; Coron	1979
[Effects of calcium antagonists on carbohydrate and lipid metabolism]. Kardiologiia, 1992, Volume: 32, Issue:4 Topics: Animals; Calcium Channel Blockers; Carbohydrate Metabolism; Cholesterol; Coronary Disease; Diabetes	1992
[A clinical case: coronary vasospasm induced by exercise after stopping nifedipine therapy]. Minerva cardioangiologica, 1992, Volume: 40, Issue:3 Topics: Coronary Disease; Coronary Vasospasm; Delayed-Action Preparations; Electrocardiography; Exercise; Ex	1992
Sustained release nifedipine formulations. An appraisal of their current uses and prospective roles in the treatment of hypertension, ischaemic heart disease and peripheral vascular disorders. Drugs, 1991, Volume: 41, Issue:5 Topics: Coronary Disease; Delayed-Action Preparations; Drug Combinations; Drug Design; Humans; Hypertension;	1991
Calcium antagonists and myocardial microperfusion. Drugs, 1991, Volume: 42 Suppl 1 Topics: Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Gallopamil; Guinea Pigs;	1991
Protective effects of calcium antagonists against ischaemia and reperfusion damage. Drugs, 1991, Volume: 42 Suppl 1 Topics: Calcium; Calcium Channel Blockers; Coronary Disease; Diltiazem; Humans; Myocardial Reperfusion Injur	1991
New concepts in ischemia prevention. Journal of cardiovascular pharmacology, 1991, Volume: 18 Suppl 9 Topics: Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Coronary Disease; Diltiazem; Dou	1991
Prevention of restenosis after PTCA: role of calcium antagonists. Journal of cardiovascular pharmacology, 1991, Volume: 18 Suppl 6 Topics: Aged; Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Coronary Disease; Diltiazem; Double-	1991
The efficacy of amlodipine in the management of ischaemic heart disease. Postgraduate medical journal, 1991, Volume: 67 Suppl 3 Topics: Amlodipine; Angina Pectoris; Calcium Channel Blockers; Coronary Disease; Drug Therapy, Combination;	1991
The pharmacological profile of amlodipine in relation to ischaemic heart disease. Postgraduate medical journal, 1991, Volume: 67 Suppl 3 Topics: Amlodipine; Animals; Calcium Channel Blockers; Cats; Coronary Disease; Dogs; Mice; Muscle Contractio	1991
A review of amlodipine in myocardial ischaemia. Postgraduate medical journal, 1991, Volume: 67 Suppl 5 Topics: Amlodipine; Angina Pectoris; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; H	1991
Calcium-antagonists in preventing restenosis following coronary angioplasty. Cardiologia (Rome, Italy), 1991, Volume: 36, Issue:12 Suppl 1 Topics: Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease	1991
Prevention of alpha-adrenergic coronary constriction by calcium-antagonists. Basic research in cardiology, 1990, Volume: 85 Suppl 1 Topics: Animals; Calcium Channel Blockers; Constriction, Pathologic; Coronary Circulation; Coronary Disease;	1990
Rationale for treatment of silent myocardial ischemia: focus on nifedipine. Cardiovascular drugs and therapy, 1990, Volume: 4 Suppl 5 Topics: Coronary Disease; Humans; Nifedipine	1990
Cardioprotective effects of amlodipine on ischemia and reperfusion in two experimental models. The American journal of cardiology, 1990, Nov-20, Volume: 66, Issue:18 Topics: Amlodipine; Animals; Calcium Channel Blockers; Cats; Coronary Disease; Dogs; In Vitro Techniques; My	1990
The efficacy of amlodipine in myocardial ischemia. American heart journal, 1989, Volume: 118, Issue:5 Pt 2 Topics: Adrenergic beta-Antagonists; Amlodipine; Angina Pectoris; Angina Pectoris, Variant; Calcium Channel	1989
Calcium channel blockade in heart failure. Cardiologia (Rome, Italy), 1989, Volume: 34, Issue:2 Topics: Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Heart; Heart Failure; Hemodyna	1989
Large vessel coronary vasospasm: diagnosis, natural history and treatment. The American journal of cardiology, 1985, Jan-25, Volume: 55, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aspirin; Coronary Artery Bypass; Coronary	1985
Calcium antagonists. Cardiology, 1985, Volume: 72, Issue:5-6 Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium; Calcium Channel Blockers; Coronary Circulatio	1985
Why Ca2+ antagonists will be most useful before or during early myocardial ischaemia and not after infarction has been established. European heart journal, 1986, Volume: 7, Issue:4 Topics: Adrenergic beta-Antagonists; Angina, Unstable; Animals; Calcium Channel Blockers; Coronary Disease;	1986
The haemodynamic effects of nifedipine, verapamil and diltiazem in patients with coronary artery disease. A review. Drugs, 1986, Volume: 32, Issue:1 Topics: Adrenergic beta-Antagonists; Benzazepines; Calcium Channel Blockers; Coronary Circulation; Coronary	1986
Assessing the total ischemic burden in the management of unstable angina. A review. The American journal of medicine, 1986, Oct-20, Volume: 81, Issue:4A Topics: Adrenergic beta-Antagonists; Angina, Unstable; Coronary Artery Bypass; Coronary Disease; Drug Therap	1986
Measurement of coronary blood flow in man: methods and implications for clinical practice. Cardiovascular clinics, 1985, Volume: 15, Issue:1 Topics: Amrinone; Angina Pectoris; Animals; Cardiomegaly; Coronary Circulation; Coronary Disease; Coronary V	1985
Nifedipine: more than a calcium channel blocker. General pharmacology, 1986, Volume: 17, Issue:3 Topics: Adenosine; Animals; Benzodiazepines; Biological Transport; Caffeine; Coronary Disease; Humans; Nifed	1986
Calcium channel antagonists. Part II: Use and comparative properties of the three prototypical calcium antagonists in ischemic heart disease, including recommendations based on an analysis of 41 trials. Cardiovascular drugs and therapy, 1988, Volume: 1, Issue:5 Topics: Angina Pectoris; Angina, Unstable; Calcium Channel Blockers; Coronary Disease; Diltiazem; Drug Thera	1988
Smoking, catecholamines, and the ischemic myocardium. Postgraduate medicine, 1988, Feb-29, Volume: Spec No Topics: Angina Pectoris; Atenolol; Catecholamines; Coronary Disease; Female; Heart; Humans; Male; Nifedipine	1988
Calcium channel blocking agents in congestive heart failure. The American journal of medicine, 1986, Feb-28, Volume: 80, Issue:2B Topics: Administration, Oral; Biological Transport; Calcium; Calcium Channel Blockers; Cardiac Output; Cardi	1986
Advances in calcium blocker therapy. American journal of surgery, 1986, Volume: 151, Issue:4 Topics: Arrhythmias, Cardiac; Arteriosclerosis; Asthma; Blood Platelet Disorders; Calcium; Calcium Channel B	1986
Mechanisms involved in reperfusion arrhythmias. European heart journal, 1986, Volume: 7 Suppl A Topics: Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Dil	1986
On a possible role for calcium antagonists in atherosclerosis. A personal view. European heart journal, 1986, Volume: 7, Issue:7 Topics: Animals; Arteriosclerosis; Calcium; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Dis	1986
Nifedipine in myocardial ischemia, systemic hypertension, and other cardiovascular disorders. Annals of internal medicine, 1986, Volume: 105, Issue:5 Topics: Angina Pectoris; Calcium Channel Blockers; Cardiovascular Diseases; Coronary Disease; Humans; Hypert	1986
Effects of calcium-channel blockers on myocardial preservation during experimental acute myocardial infarction. The American journal of cardiology, 1985, Jan-25, Volume: 55, Issue:3 Topics: Animals; Calcium Channel Blockers; Collateral Circulation; Coronary Circulation; Coronary Disease; D	1985
Calcium antagonists for acute ischemic heart disease. The American journal of cardiology, 1985, Jan-25, Volume: 55, Issue:3 Topics: Acute Disease; Angina Pectoris, Variant; Angina, Unstable; Calcium Channel Blockers; Coronary Diseas	1985
Effects of calcium-channel blocking agents on left ventricular diastolic function in hypertrophic cardiomyopathy and in coronary artery disease. The American journal of cardiology, 1985, Jan-25, Volume: 55, Issue:3 Topics: Calcium Channel Blockers; Cardiomyopathy, Hypertrophic; Coronary Disease; Heart Ventricles; Hemodyna	1985
Are calcium antagonists cardioprotective? Journal of the Royal College of Physicians of London, 1985, Volume: 19, Issue:2 Topics: Angina Pectoris; Animals; Blood Viscosity; Calcium Channel Blockers; Clinical Trials as Topic; Coron	1985
Calcium channel blocking agents: physiologic basis of nursing intervention. Heart & lung : the journal of critical care, 1985, Volume: 14, Issue:4 Topics: Angina Pectoris; Angina Pectoris, Variant; Atrioventricular Node; Calcium; Calcium Channel Blockers;	1985
Response of normal and diseased epicardial coronary arteries to vasoactive drugs: quantitative arteriographic studies. The American journal of cardiology, 1985, Sep-18, Volume: 56, Issue:9 Topics: Arterial Occlusive Diseases; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Coron	1985
Hypertensive cardiovascular emergencies. Comprehensive therapy, 1985, Volume: 11, Issue:10 Topics: Antihypertensive Agents; Brain Diseases; Cerebrovascular Disorders; Clonidine; Coronary Disease; Dia	1985
[Myocardial cellular mechanism of action of calcium antagonists]. Cardiologia (Rome, Italy), 1985, Volume: 30, Issue:2 Topics: Actin Cytoskeleton; Calcium; Calcium Channel Blockers; Coronary Disease; Diltiazem; Heart; Humans; M	1985

Article	Year
Beneficial effects of long-acting nifedipine on coronary vasomotion abnormalities after drug-eluting stent implantation: The NOVEL study. European heart journal, 2016, Sep-14, Volume: 37, Issue:35 Topics: Coronary Disease; Drug-Eluting Stents; Everolimus; Humans; Nifedipine; Prospective Studies; Sirolimu	2016
Myocardial ischaemia in patients with impaired left ventricular function undergoing coronary artery bypass grafting--milrinone versus nifedipin. European journal of anaesthesiology, 2002, Volume: 19, Issue:11 Topics: Aged; Anesthesia, General; Calcium Channel Blockers; Coronary Artery Bypass; Coronary Disease; Creat	2002
Nifedipine retard was as effective as angiotensin converting enzyme inhibitors in preventing cardiac events in high-risk hypertensive patients with diabetes and coronary artery disease: the Japan Multicenter Investigation for Cardiovascular Diseases-B (JM Hypertension research : official journal of the Japanese Society of Hypertension, 2004, Volume: 27, Issue:7 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Blood Pressure; Coronary Disease; Dia	2004
Comparison of the acute hemodynamic effects of nifedipine with nitrendipine and a study of the electrophysiological effects of nitrendipine in man. Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 7 Topics: Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Coronary Disease; Electrocardiography; El	1984
Calcium channel blockers as antihypertensive agents. The American journal of medicine, 1984, Oct-05, Volume: 77, Issue:4A Topics: Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Clinical Trials as Topic; Coronary Disease;	1984
Calcium channel blocking agents. Medical times, 1981, Volume: 109, Issue:8 Topics: Benzazepines; Calcium; Calcium Channel Blockers; Cardiomegaly; Clinical Trials as Topic; Coronary Di	1981
Acute myocardial ischaemia: what information can be expected in the near future from ongoing clinical trials with nifedipine? European heart journal, 1983, Volume: 4 Suppl C Topics: Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Electrocardiography; Humans; Metoprolol	1983
Nifedipine cardioplegia experience: results of a 3-year cooperative clinical study. The Annals of thoracic surgery, 1983, Volume: 36, Issue:6 Topics: Aged; Cardiac Output; Clinical Trials as Topic; Coronary Artery Bypass; Coronary Disease; Female; He	1983
[Anti-angina effectiveness of the calcium antagonist nifedipine in relation to coronary involvement]. Zeitschrift fur Kardiologie, 1983, Volume: 72, Issue:11 Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Coronary Circulation; Coronary Disease; Drug	1983
[Calcium antagonists in the treatment of ischemic heart disease]. Kardiologiia, 1984, Volume: 24, Issue:2 Topics: Adult; Aged; Angina Pectoris; Calcium; Clinical Trials as Topic; Coronary Disease; Female; Hemodynam	1984
[Calcium antagonists. Properties and current indications]. Recenti progressi in medicina, 1984, Volume: 75, Issue:4 Topics: Arrhythmias, Cardiac; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Diltiaze	1984
[Anti-angina effect of gallopamil in comparison with another calcium antagonist and a placebo]. Zeitschrift fur Kardiologie, 1984, Volume: 73, Issue:9 Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Coronary Disease; Double-Bli	1984
Comparative effects of nitroglycerin, nifedipine and metoprolol on regional left ventricular function in patients with one-vessel coronary disease. Circulation, 1983, Volume: 67, Issue:2 Topics: Adult; Aged; Cardiac Output; Coronary Disease; Coronary Vessels; Female; Heart Ventricles; Hemodynam	1983
The effects of nifedipine on coronary haemodynamics and exercise left ventricular function. Postgraduate medical journal, 1983, Volume: 59 Suppl 2 Topics: Coronary Circulation; Coronary Disease; Heart Function Tests; Hemodynamics; Humans; Nifedipine; Nitr	1983
[Comparison of the anti-ischemia effect of nisoldipine and verapamil. Double-blind randomized cross-over and placebo-controlled acute and long-term study]. Herz, 1984, Volume: 9, Issue:4 Topics: Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Diseas	1984
[Therapeutic effectiveness of the transdermal system with nitroglycerin in comparison with nifedipine]. Zeitschrift fur Kardiologie, 1984, Volume: 73, Issue:8 Topics: Administration, Topical; Adult; Angina Pectoris; Coronary Disease; Electrocardiography; Exercise Tes	1984
[Dynamics of critical stenosis in patients with unstable angina pectoris]. Zeitschrift fur Kardiologie, 1984, Volume: 73, Issue:9 Topics: Angina Pectoris; Angina, Unstable; Coronary Angiography; Coronary Circulation; Coronary Disease; Hem	1984
Effect of nicardipine on myocardial contractility and on angina induced by atrial pacing in patients with coronary artery disease (abstract). Postgraduate medical journal, 1984, Volume: 60 Suppl 4 Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Cardiac Pacing, Artificial;	1984
[Anti-ischemic effect of nifedipine in delayed-action form. Results of a double-blind, randomized, crossover, placebo-controlled acute study]. Herz, 1983, Volume: 8, Issue:4 Topics: Blood Pressure; Coronary Disease; Delayed-Action Preparations; Double-Blind Method; Electrocardiogra	1983
Long-term treatment of patients with coronary heart disease using isosorbide dinitrate, nifedipine and molsidomine. Zeitschrift fur Kardiologie, 1983, Volume: 72 Suppl 3 Topics: Adult; Blood Pressure; Coronary Disease; Drug Administration Schedule; Drug Tolerance; Hemodynamics;	1983
[Comparative study of the effect of the calcium antagonist nifedipine, the beta receptor blockers acebutolol and propranolol and their combination on electrophysiologic parameters in the human]. Zeitschrift fur Kardiologie, 1984, Volume: 73, Issue:2 Topics: Acebutolol; Cardiac Catheterization; Coronary Disease; Drug Therapy, Combination; Electrocardiograph	1984
Verapamil therapy for unstable angina pectoris: review of double-blind placebo-controlled randomized clinical trials. The American journal of cardiology, 1982, Volume: 50, Issue:4 Topics: Adult; Aged; Angina Pectoris; Arterial Occlusive Diseases; Clinical Trials as Topic; Coronary Diseas	1982
[Action of nifedipine on the response to exertion and on peripheral tissue oxygenation. Comparative study of healthy individuals and coronary insufficiency patients]. Revista espanola de cardiologia, 1982, Volume: 35, Issue:5 Suppl 2 Topics: Adolescent; Adult; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Exercise Test; F	1982
Therapy of coronary vasoconstriction in patients with coronary artery disease. The American journal of cardiology, 1981, Volume: 47, Issue:1 Topics: Angina Pectoris; Cold Temperature; Coronary Disease; Coronary Vessels; Exercise Test; Heart Ventricl	1981
Blood pressure and heart rate in patients with ischaemic heart disease receiving nifedipine and propranolol. British medical journal (Clinical research ed.), 1982, Apr-17, Volume: 284, Issue:6323 Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Drug T	1982
Pharmacological effects on coronary haemodynamics. A comparative study between atenolol, verapamil, nifedipine and carbocromen. Acta medica Scandinavica. Supplementum, 1981, Volume: 645 Topics: Atenolol; Chromonar; Coronary Circulation; Coronary Disease; Coumarins; Hemodynamics; Humans; Nifedi	1981
[Varying response to nifedipine during treatment of stable exertional angina pectoris: results of a double-blind, randomized, cross-over, placebo-controlled study (author's transl)]. Herz, 1982, Volume: 7, Issue:2 Topics: Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; El	1982
Combined acebutolol/nifedipine therapy in patients with chronic coronary artery disease: additional improvement of ischemia-induced left ventricular dysfunction. The American journal of cardiology, 1982, Apr-01, Volume: 49, Issue:5 Topics: Acebutolol; Adult; Aged; Blood Pressure; Coronary Disease; Drug Therapy, Combination; Exercise Test;	1982
[Left ventricular contractility, relaxation and regional wall motion following intracoronary injection of nifedipine. Evaluation by m-mode echocardiography]. Zeitschrift fur Kardiologie, 1982, Volume: 71, Issue:6 Topics: Adult; Aortic Valve Insufficiency; Cardiomyopathies; Coronary Disease; Echocardiography; Female; Hea	1982
[Drug therapy of coronary heart disease. Comparative effects of nifedipine and isosorbide dinitrate]. Die Medizinische Welt, 1982, Sep-10, Volume: 33, Issue:36 Topics: Coronary Disease; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nifedipine; Pyridines; Ra	1982
[The effect of diltiazem and nifedipine on exercise-induced ST-segment depression and heart rate in patients with coronary heart disease (author's transl)]. Zeitschrift fur Kardiologie, 1981, Volume: 70, Issue:1 Topics: Adult; Benzazepines; Coronary Disease; Diltiazem; Double-Blind Method; Electrocardiography; Female;	1981
[Comparative pharmacodynamics study of korinfar and isoptin in ischemic heart disease]. Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR, 1981, Volume: 4, Issue:1 Topics: Adult; Angina Pectoris; Coronary Disease; Dose-Response Relationship, Drug; Drug Evaluation; Exercis	1981
Prevention of nifedipine of abnormal coronary vasoconstriction in patients with coronary artery disease. Circulation, 1981, Volume: 63, Issue:4 Topics: Adult; Aged; Blood Pressure; Cardiac Catheterization; Cold Temperature; Coronary Disease; Coronary V	1981
Influence of the selection of angiographic projections on the results of coronary angiographic follow-up trials. International Nifedipine Trial on Antiatherosclerotic Therapy Investigators. American heart journal, 1995, Volume: 130, Issue:3 Pt 1 Topics: Analysis of Variance; Coronary Angiography; Coronary Disease; Disease Progression; Double-Blind Meth	1995
Comparison of the effects of nifedipine and nitroglycerin on coronary blood flow using intracoronary Doppler catheter. Journal of the Formosan Medical Association = Taiwan yi zhi, 1994, Volume: 93, Issue:6 Topics: Aged; Blood Flow Velocity; Cardiac Catheterization; Coronary Circulation; Coronary Disease; Female;	1994
Effects of treatment strategies to suppress ischemia in patients with coronary artery disease: 12-week results of the Asymptomatic Cardiac Ischemia Pilot (ACIP) study. Journal of the American College of Cardiology, 1994, Volume: 24, Issue:1 Topics: Aged; Atenolol; Coronary Disease; Diltiazem; Drug Therapy, Combination; Female; Humans; Isosorbide D	1994
Atenolol versus the fixed combination of atenolol and nifedipine in stable angina pectoris. European heart journal, 1993, Volume: 14, Issue:10 Topics: Adult; Aged; Angina Pectoris; Atenolol; Blood Pressure; Coronary Disease; Delayed-Action Preparation	1993
Angiotensin converting enzyme inhibition in chronic stable angina: effects on myocardial ischaemia and comparison with nifedipine. British heart journal, 1994, Volume: 71, Issue:1 Topics: Adult; Aged; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Chronic Diseas	1994
[The effects of the selective intracoronary administration of nifedipine on left ventricular filling anomalies during coronary angioplasty]. Cardiologia (Rome, Italy), 1993, Volume: 38, Issue:8 Topics: Adult; Analysis of Variance; Angioplasty, Balloon, Coronary; Coronary Angiography; Coronary Disease;	1993
Ischemia in collateral-dependent myocardium: effects of nifedipine and diltiazem in man. American heart journal, 1993, Volume: 126, Issue:1 Topics: Aged; Blood Pressure; Collateral Circulation; Coronary Disease; Diltiazem; Electrocardiography; Exer	1993
[Acute effects of propranolol and its association with nifedipine in aged patients with effort stable angina. Randomized double-blind crossover study, under placebo control]. Minerva cardioangiologica, 1993, Volume: 41, Issue:4 Topics: Age Factors; Aged; Angina Pectoris; Coronary Disease; Double-Blind Method; Drug Therapy, Combination	1993
Cardioprotective effect of intracoronary nifedipine during percutaneous transluminal coronary angioplasty. A French double-blind cross-over multicentre study. International journal of cardiology, 1993, Volume: 39, Issue:1 Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Coronary Disease; Coronary Vessels; Double-Blind Method	1993
Early experience with dobutamine stress testing and cardiac cine-tomographic imaging in the elderly: antianginal effects of nifedipine-GITS. Journal of the American Geriatrics Society, 1993, Volume: 41, Issue:9 Topics: Age Factors; Angina Pectoris; Cineradiography; Coronary Angiography; Coronary Disease; Dobutamine; D	1993
Usefulness of exercise testing performed with vasodilators for predicting the severity of myocardial ischaemia during daily activities and treatment. European heart journal, 1993, Volume: 14, Issue:3 Topics: Activities of Daily Living; Adult; Angina Pectoris; Coronary Circulation; Coronary Disease; Drug The	1993
[Comparison of the cardiodepressive effects of nifedipine, isradipine, nisoldipine and felodipine in patients with coronary heart disease]. Zeitschrift fur Kardiologie, 1993, Volume: 82, Issue:1 Topics: Adult; Aged; Calcium Channel Blockers; Coronary Disease; Electrocardiography; Exercise Test; Felodip	1993
Total Ischaemic Burden European Trial (TIBET). Effects of ischaemia and treatment with atenolol, nifedipine SR and their combination on outcome in patients with chronic stable angina. The TIBET Study Group. European heart journal, 1996, Volume: 17, Issue:1 Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Atenolol; Calcium Channel Blockers; Coron	1996
[The effects of treatment with trapidil compared to nifedipine on physical, emotional and cognitive exercise tolerance in patients with coronary heart disease]. Arzneimittel-Forschung, 1996, Volume: 46, Issue:9 Topics: Aged; Cognition; Coronary Disease; Double-Blind Method; Electrocardiography; Emotions; Exercise; Exe	1996
Effects of antianginal therapy with a calcium antagonist and nitrates on dobutamine-atropine stress echocardiography. Comparison with exercise electrocardiography. European heart journal, 1997, Volume: 18, Issue:2 Topics: Atropine; Calcium Channel Blockers; Cardiotonic Agents; Coronary Disease; Diltiazem; Dobutamine; Dos	1997
Relation between exercise-induced left ventricular wall motion abnormalities and coronary artery disease in hypertensive patients: effects of blood pressure normalization. American journal of hypertension, 1997, Volume: 10, Issue:3 Topics: Aged; Blood Pressure; Calcium Channel Blockers; Coronary Angiography; Coronary Disease; Echocardiogr	1997
Predictors of the progression of diabetic nephropathy and the beneficial effect of angiotensin-converting enzyme inhibitors in NIDDM patients. Diabetologia, 1997, Volume: 40, Issue:4 Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel B	1997
Effects of nicorandil, an antianginal potassium channel opener, on left ventricular systolic and diastolic function in patients with chronic coronary artery disease. The American journal of cardiology, 1997, Jun-15, Volume: 79, Issue:12 Topics: Adult; Aged; Chronic Disease; Coronary Disease; Diastole; Female; Humans; Male; Middle Aged; Niacina	1997
Myocardial oxygen supply:demand ratio as reference for coronary vasodilatory drug effects in humans. Heart (British Cardiac Society), 1997, Volume: 78, Issue:2 Topics: Aged; Cardiac Catheterization; Cardiac Pacing, Artificial; Coronary Artery Bypass; Coronary Circulat	1997
Heart rate variability and ischaemia in patients with coronary heart disease and stable angina pectoris; influence of drug therapy and prognostic value. TIBBS Investigators Group. Total Ischemic Burden Bisoprolol Study. European heart journal, 1999, Volume: 20, Issue:1 Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Bisoprolol; Calcium Channel Blockers; Cir	1999
Influence of calcium antagonists on long-term survival of patients treated with coronary angioplasty. Japanese heart journal, 1999, Volume: 40, Issue:1 Topics: Aged; Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Coronary Disease; Diltiazem; Female;	1999
Clopidogrel compatibility with concomitant cardiac co-medications: a study of its interactions with a beta-blocker and a calcium uptake antagonist. Seminars in thrombosis and hemostasis, 1999, Volume: 25 Suppl 2 Topics: Adrenergic beta-Antagonists; Adult; Arterial Occlusive Diseases; Atenolol; Calcium Channel Blockers;	1999
Effects of a slow-release nifedipine on 24-hour ambulatory blood pressure and ischemic changes on 24-hour ambulatory electrocardiogram in patients with severe coronary artery disease. Cardiology, 2000, Volume: 94, Issue:1 Topics: Aged; Aged, 80 and over; Analysis of Variance; Blood Pressure Monitoring, Ambulatory; Calcium Channe	2000
[Drug therapy of coronary heart disease (author's transl)]. Arzneimittel-Forschung, 1977, Volume: 27, Issue:3a Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium; Clinical Trials as Topic; Coronary Disease; D	1977
Therapeutic effects of pindolol and nifedipine in patients with stable angina pectoris and asymptomatic resting ischemia. European journal of cardiology, 1979, Volume: 10, Issue:1 Topics: Adult; Aged; Angina Pectoris; Coronary Disease; Female; Hemodynamics; Humans; Male; Middle Aged; Nif	1979
[Clinical trial of nifedipine in ischemic cardiopathy. Comparison of the traditional evaluation and effects on cardiac metabolism]. Bollettino della Societa italiana di cardiologia, 1978, Volume: 23, Issue:8 Topics: Adult; Aged; Clinical Trials as Topic; Coronary Disease; Creatine Kinase; Cyclic AMP; Fatty Acids; F	1978
[Chemotherapy in ischemic heart disease. Experience with Nifedipine (Corinfar)]. Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1977, Oct-01, Volume: 32, Issue:19 Topics: Adult; Aged; Clinical Trials as Topic; Coronary Circulation; Coronary Disease; Female; Hemodynamics;	1977
[Nifedipine (adalate) in the treatment of angina pectoris]. Vutreshni bolesti, 1978, Volume: 17, Issue:1 Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Dose-Response Relationship	1978
[Initial experience. Comparative study of verapamil and nifedipine in the treatment of coronary insufficiency. Evaluation by a cycloergometric test]. Arquivos brasileiros de cardiologia, 1978, Volume: 31 Suppl 1 Topics: Adult; Aged; Chronic Disease; Cineangiography; Clinical Trials as Topic; Coronary Disease; Double-Bl	1978
[The Adalat field study--1 year later. Experience from a follow-up of 2,878 patients]. Die Medizinische Welt, 1979, Mar-23, Volume: 30, Issue:12 Topics: Clinical Trials as Topic; Coronary Disease; Female; Follow-Up Studies; Germany, West; Humans; Male;	1979
[Computerized analysis of the changes induced with nifedipine in the exercise ECG]. Bollettino della Societa italiana di cardiologia, 1977, Volume: 22, Issue:7 Topics: Administration, Oral; Adult; Clinical Trials as Topic; Computers; Coronary Circulation; Coronary Dis	1977
[Results of a trial of a coronary therapeutic agent, Adalat (author's transl)]. MMW, Munchener medizinische Wochenschrift, 1977, Feb-18, Volume: 119, Issue:7 Topics: Aged; Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Drug Evaluation; Female; Humans;	1977
[Scintigraphic studies on the influence of coronary-effective drugs on myocardial perfusion during rest]. Zeitschrift fur Kardiologie, 1976, Volume: 65, Issue:9 Topics: Aged; Contrast Media; Coronary Circulation; Coronary Disease; Dipyridamole; Female; Humans; Male; Mi	1976
[Results of a field trial of the coronary drug Adalat (BAY a 1040)]. Die Medizinische Welt, 1975, Oct-03, Volume: 26, Issue:40 Topics: Aged; Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Drug Evaluation; Female; Humans;	1975
Antianginal and anti-ischemic efficacy of nicorandil compared with nifedipine in patients with angina pectoris and coronary heart disease: a double-blind, randomized, multicenter study. Journal of cardiovascular pharmacology, 1992, Volume: 20 Suppl 3 Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Coronary Disease; Double-Blind Method; Electrocardiogr	1992
Treatment of transient myocardial ischemia in patients with stable angina: a comparative study of verapamil slow-release and nifedipine plus propranolol. Journal of cardiovascular pharmacology, 1992, Volume: 19, Issue:4 Topics: Adult; Aged; Angina Pectoris; Coronary Disease; Delayed-Action Preparations; Drug Therapy, Combinati	1992
Amlodipine versus nifedipine retard in the treatment of chronic ischemic heart disease. La Clinica terapeutica, 1992, Volume: 140, Issue:1 Topics: Adult; Aged; Amlodipine; Calcium Channel Blockers; Chronic Disease; Coronary Disease; Delayed-Action	1992
Optimal control of myocardial ischaemia: the benefit of a fixed combination of atenolol and nifedipine in patients with chronic stable angina. British heart journal, 1992, Volume: 68, Issue:3 Topics: Adult; Aged; Angina Pectoris; Atenolol; Coronary Disease; Double-Blind Method; Drug Administration S	1992
[Effect of corinfar on hemodynamic indicators and clinical manifestations in patients with ischemic heart disease and stenocardia during psycho-emotional stress]. Kardiologiia, 1992, Volume: 32, Issue:3 Topics: Adult; Angina Pectoris; Blood Pressure; Coronary Disease; Electrocardiography; Exercise Test; Heart	1992
[The anti-ischemic effect of gallopamil-retard in comparison with nifedipine-retard in stable angina pectoris]. Zeitschrift fur Kardiologie, 1992, Volume: 81, Issue:10 Topics: Aged; Angina Pectoris; Blood Pressure; Coronary Disease; Delayed-Action Preparations; Dose-Response	1992
24-hour anti-ischaemic action with once daily nifedipine. Experience obtained with a fatty-alcohol matrix tablet in patients with coronary artery disease. European journal of clinical pharmacology, 1992, Volume: 43, Issue:6 Topics: Aged; Angina Pectoris; Coronary Disease; Delayed-Action Preparations; Double-Blind Method; Drug Admi	1992
The total ischemic burden European trial (TIBET): design, methodology, and management. The TIBET Study Group. Cardiovascular drugs and therapy, 1992, Volume: 6, Issue:4 Topics: Adult; Aged; Angina Pectoris; Atenolol; Coronary Disease; Data Interpretation, Statistical; Double-B	1992
Intravenous nifedipine to treat hypertension after coronary artery revascularization surgery. A comparison with sodium nitroprusside. Anesthesia and analgesia, 1992, Volume: 74, Issue:6 Topics: Blood Pressure; Coronary Artery Bypass; Coronary Disease; Creatine Kinase; Electrocardiography, Ambu	1992
Efficacy and tolerability of gallopamil in coronary heart disease: a double blind cross-over comparison with nifedipine. European heart journal, 1992, Volume: 13, Issue:4 Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Coronary Disease; Double-Blind Method; Electrocardiogr	1992
Effect of isradipine on left ventricular relaxation and diastolic filling. Journal of cardiovascular pharmacology, 1990, Volume: 15 Suppl 1 Topics: Angiocardiography; Blood Pressure; Calcium Channel Blockers; Cardiac Catheterization; Coronary Disea	1990
Antiischemic and hemodynamic effects of intravenous isradipine, a new calcium antagonist, in coronary heart disease: a comparative double-blind cross-over study with nifedipine. Journal of cardiovascular pharmacology, 1990, Volume: 16, Issue:5 Topics: Calcium Channel Blockers; Coronary Disease; Double-Blind Method; Hemodynamics; Humans; Isradipine; M	1990
New concepts in ischemia prevention. Journal of cardiovascular pharmacology, 1991, Volume: 18 Suppl 9 Topics: Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Coronary Disease; Diltiazem; Dou	1991
Prevention of restenosis after PTCA: role of calcium antagonists. Journal of cardiovascular pharmacology, 1991, Volume: 18 Suppl 6 Topics: Aged; Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Coronary Disease; Diltiazem; Double-	1991
Felodipine (once daily) versus nifedipine (four times daily) for Prinzmetal's angina pectoris. The American journal of cardiology, 1991, Dec-15, Volume: 68, Issue:17 Topics: Angina Pectoris, Variant; Coronary Angiography; Coronary Disease; Double-Blind Method; Electrocardio	1991
Anti-ischaemic properties of amlodipine, a new calcium antagonist, in patients with severe coronary artery disease: a prospective trial. Postgraduate medical journal, 1991, Volume: 67 Suppl 5 Topics: Amlodipine; Angina Pectoris; Calcium Channel Blockers; Coronary Disease; Exercise Test; Female; Hear	1991
Open comparative study to assess the efficacy and safety of two calcium antagonists, amlodipine and diltiazem, in the treatment of symptomatic myocardial ischaemia. Postgraduate medical journal, 1991, Volume: 67 Suppl 5 Topics: Amlodipine; Angina Pectoris; Coronary Disease; Diltiazem; Hemodynamics; Humans; Middle Aged; Nifedip	1991
Clinical investigation of asymptomatic cardiac ischemia. Clinical cardiology, 1991, Volume: 14, Issue:12 Topics: Angina Pectoris; Angioplasty, Balloon, Coronary; Atenolol; Coronary Artery Bypass; Coronary Disease;	1991
Calcium-antagonists in preventing restenosis following coronary angioplasty. Cardiologia (Rome, Italy), 1991, Volume: 36, Issue:12 Suppl 1 Topics: Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease	1991
Attenuation of circadian variation by combined antianginal therapy with suppression of morning and evening increases in transient myocardial ischemia. American heart journal, 1991, Volume: 122, Issue:3 Pt 1 Topics: Angina Pectoris; Circadian Rhythm; Coronary Disease; Double-Blind Method; Drug Therapy, Combination;	1991
Influence of calcium administration on the short-term hemodynamic and anti-ischemic effects of nifedipine. Journal of the American College of Cardiology, 1991, Volume: 18, Issue:4 Topics: Blood Pressure; Calcium Chloride; Coronary Disease; Double-Blind Method; Exercise Test; Female; Hemo	1991
Nifedipine reduces the incidence of myocardial infarction and transient ischemia in patients undergoing coronary bypass grafting. Circulation, 1991, Volume: 83, Issue:2 Topics: Coronary Artery Bypass; Coronary Disease; Creatine Kinase; Electrocardiography; Electrocardiography,	1991
Efficacy of slow-release nifedipine on myocardial ischemic episodes in variant angina pectoris. The American journal of cardiology, 1991, Sep-01, Volume: 68, Issue:6 Topics: Aged; Aged, 80 and over; Angina Pectoris, Variant; Circadian Rhythm; Coronary Disease; Delayed-Actio	1991
[Effects of antianginal drugs on left ventricular diastolic filling in patients with ischemic heart disease]. Kokyu to junkan. Respiration & circulation, 1991, Volume: 39, Issue:8 Topics: Aged; Coronary Disease; Diastole; Drug Evaluation; Exercise Test; Gated Blood-Pool Imaging; Heart; H	1991
Effect of nifedipine on total ischemic activity and circadian distribution of myocardial ischemic episodes in angina pectoris. The American journal of cardiology, 1991, Jan-15, Volume: 67, Issue:2 Topics: Angina Pectoris; Circadian Rhythm; Coronary Disease; Double-Blind Method; Electrocardiography, Ambul	1991
Anti-ischemic effects of atenolol versus nifedipine in patients with coronary artery disease and ambulatory silent ischemia. Journal of the American College of Cardiology, 1991, Mar-15, Volume: 17, Issue:4 Topics: Angina Pectoris; Atenolol; Circadian Rhythm; Coronary Disease; Double-Blind Method; Electrocardiogra	1991
Effects of atenolol alone, nifedipine alone and their combination on ambulant myocardial ischemia. The American journal of cardiology, 1991, Apr-01, Volume: 67, Issue:8 Topics: Adult; Aged; Angina Pectoris; Atenolol; Coronary Disease; Double-Blind Method; Drug Therapy, Combina	1991
Transient myocardial ischemia during daily life in rest and exertional angina pectoris and comparison of effectiveness of metoprolol versus nifedipine. The American journal of cardiology, 1991, May-01, Volume: 67, Issue:11 Topics: Angina Pectoris; Circadian Rhythm; Coronary Angiography; Coronary Disease; Double-Blind Method; Elec	1991
Therapeutic implications of dynamic coronary stenosis in patients with single vessel coronary artery disease. European heart journal, 1991, Volume: 12, Issue:4 Topics: Adult; Aged; Atenolol; Cardiac Catheterization; Coronary Disease; Double-Blind Method; Electrocardio	1991
Protective effects of pretreatment with intracoronary nifedipine on myocardial ischemia and dysfunction. Cardiovascular drugs and therapy, 1990, Volume: 4 Suppl 5 Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Blood Pressure; Coronary Disease; Electrocardiography;	1990
Efficacy of slow-release nifedipine on ischemic attacks in patients with variant angina. Cardiovascular drugs and therapy, 1990, Volume: 4 Suppl 5 Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris, Variant; Coronary Disease; Delayed-Action Preparati	1990
Acute effects of nifedipine versus isosorbide dinitrate on exercise tolerance in patients with isolated coronary artery occlusion and collaterals. Cardiovascular drugs and therapy, 1990, Volume: 4 Suppl 5 Topics: Angina Pectoris; Angiography; Arterial Occlusive Diseases; Collateral Circulation; Coronary Disease;	1990
Effects of nifedipine on left ventricular diastolic dysfunction after myocardial infarction. Cardiovascular drugs and therapy, 1990, Volume: 4 Suppl 5 Topics: Adult; Aged; Coronary Disease; Diastole; Echocardiography, Doppler; Exercise Test; Heart; Heart Vent	1990
Rationale for treatment of silent myocardial ischemia: focus on nifedipine. Cardiovascular drugs and therapy, 1990, Volume: 4 Suppl 5 Topics: Coronary Disease; Humans; Nifedipine	1990
[The comparative efficacy of nicardipine and nifedipine in stenocardia patients]. Terapevticheskii arkhiv, 1990, Volume: 62, Issue:10 Topics: Angina Pectoris; Chronic Disease; Coronary Disease; Electrocardiography; Exercise Test; Humans; Male	1990
Infusion of nifedipine after coronary artery bypass grafting decreases the incidence of early postoperative myocardial ischemia. The Annals of thoracic surgery, 1990, Volume: 49, Issue:1 Topics: Blood Pressure; Cardiac Output; Coronary Artery Bypass; Coronary Disease; Creatine Kinase; Electroca	1990
Silent ischemia: to treat or not. American heart journal, 1990, Volume: 120, Issue:3 Topics: Clinical Trials as Topic; Coronary Disease; Electrocardiography, Ambulatory; Exercise Test; Humans;	1990
[Prognostic evaluation of the effects of nitroglycerin and corinfar in the prevention of stress-induced myocardial damage]. Kardiologiia, 1990, Volume: 30, Issue:4 Topics: Adult; Aged; Clinical Trials as Topic; Coronary Disease; Dose-Response Relationship, Drug; Hemodynam	1990
Comparison of propranolol, diltiazem, and nifedipine in the treatment of ambulatory ischemia in patients with stable angina. Differential effects on ambulatory ischemia, exercise performance, and anginal symptoms. The ASIS Study Group. Circulation, 1990, Volume: 82, Issue:6 Topics: Angina Pectoris; Blood Pressure; Coronary Disease; Diltiazem; Electrocardiography, Ambulatory; Exerc	1990
Intravenous nifedipine prevents ergonovine-induced myocardial ischemia in patients with stable effort angina. Cardiovascular drugs and therapy, 1990, Volume: 4 Suppl 5 Topics: Angina Pectoris; Blood Pressure; Coronary Disease; Ergonovine; Exercise Test; Female; Heart Rate; Hu	1990
[Myocardial effects of the calcium antagonists nifedipine, nisoldipine and isradipine in coronary heart disease]. Deutsche medizinische Wochenschrift (1946), 1990, May-11, Volume: 115, Issue:19 Topics: Blood Pressure; Calcium Channel Blockers; Coronary Disease; Heart; Heart Rate; Humans; Infusions, In	1990
An exercise hemodynamic comparison of verapamil, diltiazem, and amlodipine in coronary artery disease. Cardiovascular drugs and therapy, 1990, Volume: 4, Issue:2 Topics: Amlodipine; Angina Pectoris; Calcium Channel Blockers; Cardiac Output; Coronary Disease; Diltiazem;	1990
[The use of metoprolol with calcium antagonists of different mechanisms of action (diltiazem and nifedipine) in patients with stenocardia of effort]. Terapevticheskii arkhiv, 1990, Volume: 62, Issue:1 Topics: Adult; Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Diltiazem; Drug Therapy, Combina	1990
[Effect of vasodilator agents on the character and incidence of cardiac arrhythmia in chronic heart failure]. Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1990, Mar-01, Volume: 45, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Arrhythmias, Cardiac; Atrial Fibrillation; Captopril; Cardiac Output	1990
[The effect of intravenous nifedipine administration on coronary occlusion during coronary angioplasty on ischemia tolerance and collateral function]. Zeitschrift fur Kardiologie, 1990, Volume: 79, Issue:3 Topics: Adult; Aged; Angina, Unstable; Angioplasty, Balloon, Coronary; Blood Pressure; Clinical Trials as To	1990
[Efficacy of prophylactic nifedipine therapy during aortocoronary vein bypass interventions. Drug concentration with oral or intravenous nifedipine administration; hemodynamics and plasma catecholamines]. Herz, 1990, Volume: 15, Issue:4 Topics: Administration, Oral; Adult; Aged; Chromatography, High Pressure Liquid; Coronary Artery Bypass; Cor	1990
[The effect of calcium antagonists on the hemodynamic function in patients with heart failure]. Vrachebnoe delo, 1990, Issue:7 Topics: Calcium Channel Blockers; Cardiography, Impedance; Coronary Disease; Echocardiography; Heart Failure	1990
[The results of a clinical study of the preparation kardil]. Terapevticheskii arkhiv, 1990, Volume: 62, Issue:8 Topics: Coronary Disease; Diltiazem; Dose-Response Relationship, Drug; Humans; Hypertension; Nifedipine; USS	1990
Pharmacodynamics of amlodipine: hemodynamic effects and antianginal efficacy after atrial pacing. American heart journal, 1989, Volume: 118, Issue:5 Pt 2 Topics: Amlodipine; Angina Pectoris; Calcium Channel Blockers; Cardiac Catheterization; Cardiac Pacing, Arti	1989
Antiischemic properties of amlodipine, a new calcium antagonist, in patients with severe coronary artery disease: a prospective trial. American heart journal, 1989, Volume: 118, Issue:5 Pt 2 Topics: Aged; Amlodipine; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Exercise Tes	1989
The Nifedipine-Total Ischemia Awareness Program: a national survey of painful and painless myocardial ischemia including results of antiischemic therapy. The American journal of cardiology, 1989, Mar-01, Volume: 63, Issue:9 Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angina Pectoris; Coronary Disease; Cros	1989
Anti-ischemic effects of celiprolol in patients with exercise-induced angina pectoris. International journal of cardiology, 1989, Volume: 25, Issue:1 Topics: Adrenergic beta-Antagonists; Aged; Blood Pressure; Celiprolol; Coronary Disease; Drug Synergism; Dru	1989
[Cordipine in the treatment of patients with exacerbated coronary disease]. Wiadomosci lekarskie (Warsaw, Poland : 1960), 1989, Feb-15, Volume: 42, Issue:4 Topics: Adrenergic beta-Antagonists; Adult; Aged; Clinical Trials as Topic; Coronary Disease; Drug Therapy,	1989
[The acute hemodynamic effects of the new vasodilating beta blocker carvedilol in comparison with combined administration of nifedipine and propranolol in patients with coronary heart disease]. Zeitschrift fur Kardiologie, 1989, Volume: 78, Issue:11 Topics: Carbazoles; Carvedilol; Coronary Circulation; Coronary Disease; Drug Therapy, Combination; Female; H	1989
Silent myocardial ischemia: improvement with nisoldipine therapy. Southern medical journal, 1989, Volume: 82, Issue:1 Topics: Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Electroca	1989
[Evaluation of the effectiveness of corinfar in patients with ischemic heart disease using a method of repeated transesophageal electric stimulation of the left atrium]. Kardiologiia, 1989, Volume: 29, Issue:3 Topics: Adult; Aged; Cardiac Pacing, Artificial; Clinical Trials as Topic; Coronary Disease; Esophagus; Fema	1989
Calcium channel blockade in heart failure. Cardiologia (Rome, Italy), 1989, Volume: 34, Issue:2 Topics: Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Heart; Heart Failure; Hemodyna	1989
[Comparative evaluation of the anti-anginal effects of dilzem and corinfar in patients with ischemic heart disease and exertion-induced stenocardia]. Kardiologiia, 1989, Volume: 29, Issue:4 Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Diltiazem; Female; Humans;	1989
Usefulness of nifedipine for myocardial ischemia and the nifedipine gastrointestinal therapeutic system. The American journal of cardiology, 1989, Sep-19, Volume: 64, Issue:11 Topics: Angina Pectoris; Coronary Disease; Delayed-Action Preparations; Double-Blind Method; Drug Administra	1989
[Dose-response relation of gallopamil in comparison with nifedipine, diltiazem and tiapamil in patients with coronary heart disease]. Zeitschrift fur Kardiologie, 1989, Volume: 78 Suppl 5 Topics: Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Calcium Channel Blockers; Clinical Trials as Top	1989
Hemodynamic and adrenergic effects of combined alpha/beta-receptor blockade versus combined beta-receptor and slow channel calcium blockade in patients with ischemic heart disease. International journal of cardiology, 1989, Volume: 25, Issue:1 Topics: Adult; Aged; Blood Pressure; Coronary Disease; Drug Therapy, Combination; Exercise Test; Hemodynamic	1989
Differential hemodynamic effects of beta-adrenoceptor blockers, Ca antagonists and combined alpha-beta-receptor blockade in ischemic heart disease. Acta medica Scandinavica, 1986, Volume: 219, Issue:1 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Blood Pressure; Calcium Channel Blockers;	1986
Circadian variation of total ischaemic burden and its alteration with anti-anginal agents. Lancet (London, England), 1988, Oct-01, Volume: 2, Issue:8614 Topics: Adult; Aged; Angina Pectoris; Atenolol; Circadian Rhythm; Clinical Trials as Topic; Coronary Disease	1988
The effects of intravenous nifedipine on cardiac hemodynamics and contractility in patients with coronary artery disease in the presence or absence of beta adrenergic blockade. Cardiovascular drugs and therapy, 1987, Volume: 1, Issue:4 Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Blood Pressure; Coronary Circulation; Coronary Disea	1987
Effect of nifedipine on recurrent stenosis after percutaneous transluminal coronary angioplasty. Journal of the American College of Cardiology, 1986, Volume: 8, Issue:6 Topics: Adult; Aged; Angioplasty, Balloon; Coronary Disease; Humans; Middle Aged; Nifedipine; Patient Compli	1986
[Therapeutic value of a combination of trimetazidine with a calcium inhibitor in the treatment of chronic coronary insufficiency]. Presse medicale (Paris, France : 1983), 1986, Oct-16, Volume: 15, Issue:35 Topics: Chronic Disease; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Drug Therapy, Comb	1986
A haemodynamic dose finding study with a new slow-calcium channel blocker (amlodipine) in coronary artery disease. Herz, 1986, Volume: 11, Issue:6 Topics: Adult; Aged; Amlodipine; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Cardiac Output;	1986
Regional cardioprotection by subselective intracoronary nifedipine is not due to enhanced collateral flow during coronary angioplasty. International journal of cardiology, 1987, Volume: 16, Issue:1 Topics: Aged; Angioplasty, Balloon; Coronary Circulation; Coronary Disease; Electrocardiography; Heart; Huma	1987
Comparative hemodynamic dose-response effects of five slow calcium channel-blocking agents in coronary artery disease. Clinical pharmacology and therapeutics, 1987, Volume: 42, Issue:4 Topics: Amlodipine; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Diltiazem; Dose-Re	1987
Comparison of isradipine and nifedipine in chronic stable angina. International journal of cardiology, 1988, Volume: 18, Issue:1 Topics: Aged; Angina Pectoris; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Double-	1988
Effects of nitroglycerin and nifedipine on coronary and systemic hemodynamics during transient coronary artery occlusion. American heart journal, 1988, Volume: 115, Issue:6 Topics: Adult; Aged; Angioplasty, Balloon; Blood Pressure; Collateral Circulation; Coronary Circulation; Cor	1988
[Effects of chronic administration of several calcium antagonists on pituitary release of TSH]. La Clinica terapeutica, 1987, Aug-31, Volume: 122, Issue:4 Topics: Adult; Atenolol; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Humans; Hyper	1987
[Isradipine (PN 200-110), a new dihydropyridine calcium antagonist with slight negative inotropic properties in comparison with nifedipine]. Zeitschrift fur Kardiologie, 1988, Volume: 77, Issue:6 Topics: Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Coronary Disease; Heart Rate; Hemodynamic	1988
[Clinical evaluation of fendiline as a coronary drug]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1988, Feb-08, Volume: 43, Issue:6 Topics: Adult; Aged; Clinical Trials as Topic; Coronary Disease; Fendiline; Humans; Middle Aged; Nifedipine;	1988
The effects of nisoldipine on left ventricular filling rate in patients with ischemic heart disease measured with radionuclide gated blood pool scintigraphy. European journal of nuclear medicine, 1988, Volume: 14, Issue:11 Topics: Adult; Aged; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Double-Blind Meth	1988
[Effect of preoperative continuous nifedipine maintenance medication on hemodynamics and myocardial lactate extraction in coronary surgery patients]. Anasthesie, Intensivtherapie, Notfallmedizin, 1988, Volume: 23, Issue:6 Topics: Anesthesia, General; Clinical Trials as Topic; Coronary Artery Bypass; Coronary Disease; Delayed-Act	1988
Anti-ischaemic and anti-anginal activity of atenolol, nifedipine and their combination in stable, chronic effort angina. Drugs under experimental and clinical research, 1988, Volume: 14, Issue:11 Topics: Angina Pectoris; Atenolol; Blood Pressure; Clinical Trials as Topic; Coronary Disease; Double-Blind	1988
Usefulness of PY 108-068, a new calcium channel blocker, for angina pectoris. The American journal of cardiology, 1986, Jan-01, Volume: 57, Issue:1 Topics: Aged; Angina Pectoris; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Double-	1986
[Use of a static exercise test for evaluating anti-angina effects of drugs in patients with ischemic heart disease at a polyclinic]. Kardiologiia, 1988, Volume: 28, Issue:10 Topics: Adult; Aged; Ambulatory Care; Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Electroca	1988
Preload or afterload reduction: which is more beneficial for patients with ischemic heart disease? Cardiovascular drugs and therapy, 1988, Volume: 2, Issue:1 Topics: Coronary Disease; Female; Hemodynamics; Humans; Male; Middle Aged; Molsidomine; Nifedipine; Random A	1988
[Antihypertensive and anti-ischemic effect of nitrendipine. Double-blind, randomized, crossover and placebo controlled acute study]. Herz, 1985, Volume: 10, Issue:1 Topics: Angina Pectoris; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Double-Blind	1985
Atenolol and/or nifedipine in effort angina: which is the treatment of choice for exercise coronary protection? International journal of clinical pharmacology, therapy, and toxicology, 1988, Volume: 26, Issue:9 Topics: Adult; Aged; Angina Pectoris; Atenolol; Coronary Disease; Double-Blind Method; Drug Therapy, Combina	1988
Anti-ischemic effects of slow-release formulations of nifedipine, isosorbide-5-mononitrate and their combination in patients with coronary heart disease. Cardiology, 1988, Volume: 75, Issue:6 Topics: Coronary Disease; Delayed-Action Preparations; Double-Blind Method; Drug Therapy, Combination; Elect	1988
Nifedipine prevents the pressor response to laryngoscopy and tracheal intubation in patients with coronary artery disease. Anaesthesia, 1988, Volume: 43, Issue:6 Topics: Adult; Blood Pressure; Coronary Artery Bypass; Coronary Disease; Female; Heart Rate; Humans; Intubat	1988
Smoking, catecholamines, and the ischemic myocardium. Postgraduate medicine, 1988, Feb-29, Volume: Spec No Topics: Angina Pectoris; Atenolol; Catecholamines; Coronary Disease; Female; Heart; Humans; Male; Nifedipine	1988
Nitrates and calcium antagonists for silent myocardial ischemia. The American journal of cardiology, 1988, Mar-25, Volume: 61, Issue:9 Topics: Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Electrocardiography; Female; Humans	1988
[Comparison of the acute hemodynamic effect of nisoldipine (Bay k 5552) and nifedipine in patients with ischemia-induced left ventricular impaired function]. Zeitschrift fur Kardiologie, 1988, Volume: 77, Issue:4 Topics: Adult; Aged; Calcium Channel Blockers; Cardiac Catheterization; Clinical Trials as Topic; Coronary D	1988
A comparison of the acute hemodynamic effects of nifedipine and nisoldipine in patients with ischemic reduced left ventricular function. European journal of nuclear medicine, 1987, Volume: 13, Issue:2 Topics: Aged; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Female; Hemodynamics; Humans;	1987
Changes in haemodynamics and left ventricular function during intravenous nifedipine infusion with and without additional propranolol in patients with coronary artery disease. A randomized, placebo controlled trial. European journal of clinical pharmacology, 1987, Volume: 33, Issue:4 Topics: Angiography; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Heart; Heart Rate; Hem	1987
[Clinical observations of using nifedipine in coronary disease]. Kardiologia polska, 1987, Volume: 30 Suppl Topics: Adult; Aged; Clinical Trials as Topic; Coronary Disease; Female; Hemodynamics; Humans; Male; Middle	1987
Effects of long-term treatment with 120 mg of sustained-release isosorbide dinitrate and 60 mg of sustained-release nifedipine on myocardial perfusion. The American journal of cardiology, 1988, Mar-25, Volume: 61, Issue:9 Topics: Adult; Aged; Coronary Circulation; Coronary Disease; Drug Therapy, Combination; Electrocardiography;	1988
Calcium-channel blockers for combined angina pectoris and systemic hypertension. The American journal of cardiology, 1986, Feb-26, Volume: 57, Issue:7 Topics: Adult; Aged; Angina Pectoris; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chr	1986
Randomized placebo-controlled comparative study of nifedipine, verapamil and isosorbide dinitrate in the treatment of angina at rest. European heart journal, 1986, Volume: 7, Issue:1 Topics: Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Delayed-Action Preparations; Dose-Respo	1986
[Treatment of a stable form of coronary disease with Adalat retard]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1986, Mar-03, Volume: 41, Issue:9 Topics: Adult; Aged; Clinical Trials as Topic; Coronary Disease; Delayed-Action Preparations; Female; Follow	1986
[Effect of corinfar on hemodynamics in ischemic heart disease]. Terapevticheskii arkhiv, 1986, Volume: 58, Issue:5 Topics: Blood Pressure; Cardiac Output; Cardiac Volume; Clinical Trials as Topic; Coronary Disease; Double-B	1986
On a possible role for calcium antagonists in atherosclerosis. A personal view. European heart journal, 1986, Volume: 7, Issue:7 Topics: Animals; Arteriosclerosis; Calcium; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Dis	1986
Calcium-channel blockers for combined systemic hypertension and myocardial ischemia. Circulation, 1987, Volume: 75, Issue:6 Pt 2 Topics: Angina Pectoris; Calcium Channel Blockers; Chronic Disease; Clinical Trials as Topic; Coronary Disea	1987
Effects of verapamil and nifedipine on rate of left ventricular relaxation in coronary arterial disease patients. International journal of cardiology, 1987, Volume: 14, Issue:3 Topics: Blood Pressure; Coronary Disease; Diastole; Heart Ventricles; Hemodynamics; Humans; Male; Middle Age	1987
[Change in the diameter of the coronary vessels following sublingual or intravenous nifedipine administration correlated with the plasma level]. Zeitschrift fur Kardiologie, 1987, Volume: 76, Issue:6 Topics: Administration, Oral; Coronary Circulation; Coronary Disease; Coronary Vessels; Female; Humans; Infu	1987
PY 108-068--acute effects of a single oral dose in chronic stable angina. European journal of clinical pharmacology, 1986, Volume: 30, Issue:2 Topics: Administration, Oral; Aged; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Chronic Disea	1986
[Hemodynamic effects of nisoldipine (Bay k 5552), a calcium antagonist, in coronary surgery patients]. Der Anaesthesist, 1986, Volume: 35, Issue:10 Topics: Calcium Channel Blockers; Coronary Disease; Coronary Vasospasm; Extracorporeal Circulation; Hemodyna	1986
Effect of early treatment with nifedipine in suspected acute myocardial infarction. European heart journal, 1986, Volume: 7, Issue:10 Topics: Acute Disease; Coronary Disease; Creatine Kinase; Female; Humans; Male; Middle Aged; Myocardial Infa	1986
A haemodynamic study of the effects of combined slow-calcium channel blockade (nisoldipine) and beta-blockade (metoprolol) in coronary heart disease. International journal of cardiology, 1986, Volume: 13, Issue:2 Topics: Adult; Angina Pectoris; Calcium Channel Blockers; Coronary Disease; Drug Therapy, Combination; Hemod	1986
Hemodynamic effects of molsidomine, isosorbide dinitrate, and nifedipine at rest and during exercise. American heart journal, 1985, Volume: 109, Issue:3 Pt 2 Topics: Adult; Blood Pressure; Coronary Disease; Heart Rate; Hemodynamics; Humans; Isosorbide Dinitrate; Mid	1985
Acute coronary hemodynamic effects of equihypotensive doses of nisoldipine and diltiazem. Australian and New Zealand journal of medicine, 1985, Volume: 15, Issue:6 Topics: Adult; Aged; Benzazepines; Blood Flow Velocity; Calcium Channel Blockers; Coronary Disease; Coronary	1985
Safety of acute calcium antagonist withdrawal: studies in patients with unstable angina withdrawn from nifedipine. The American journal of cardiology, 1985, May-17, Volume: 55, Issue:12 Topics: Angina Pectoris; Angina, Unstable; Coronary Artery Bypass; Coronary Disease; Double-Blind Method; El	1985
Use of nifedipine to decrease ischemic-reperfusion injury in the surgical setting. The American journal of cardiology, 1985, Jan-25, Volume: 55, Issue:3 Topics: Animals; Cardiac Output; Cardiopulmonary Bypass; Clinical Trials as Topic; Coronary Disease; Dogs; D	1985
Are calcium antagonists cardioprotective? Journal of the Royal College of Physicians of London, 1985, Volume: 19, Issue:2 Topics: Angina Pectoris; Animals; Blood Viscosity; Calcium Channel Blockers; Clinical Trials as Topic; Coron	1985
Left ventricular performance in unstable angina: assessment with radionuclide techniques. International journal of cardiology, 1985, Volume: 8, Issue:3 Topics: Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Coronary Angiography; Coronary Disease;	1985
A dose-ranging, placebo-controlled, double-blind trial of nisoldipine in effort angina: duration and extent of antianginal effects. Journal of the American College of Cardiology, 1985, Volume: 6, Issue:2 Topics: Aged; Angina Pectoris; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Dose-Re	1985
[Role of many hours of ECG monitoring (Holter method) in the diagnosis of ischemic heart disease and the selection and evaluation of antianginal therapy]. Kardiologiia, 1985, Volume: 25, Issue:9 Topics: Angina Pectoris; Clinical Trials as Topic; Coronary Angiography; Coronary Disease; Electrocardiograp	1985
Effect of short and long term administration of amiodarone on ischaemia-induced left ventricular dysfunction. Implications for combined antianginal drug therapy. Drugs, 1985, Volume: 29 Suppl 3 Topics: Adult; Amiodarone; Angina Pectoris; Benzofurans; Coronary Disease; Female; Hemodynamics; Humans; Mal	1985
[Long-term therapy of stress angina pectoris by a single daily administration of 120 mg isosorbide dinitrate in retard form. Comparison of monotherapy and combination therapy with atenolol and nifedipine]. Herz, 1985, Volume: 10, Issue:3 Topics: Angina Pectoris; Atenolol; Biotransformation; Coronary Disease; Delayed-Action Preparations; Drug Ad	1985
Short-term effect of nifedipine on effort tolerance in patients with angina pectoris. Clinical cardiology, 1986, Volume: 9, Issue:2 Topics: Administration, Oral; Adult; Aged; Angina Pectoris; Blood Pressure; Coronary Disease; Double-Blind M	1986
[Differential therapy with calcium antagonists. Hemodynamic studies using nifedipine, verapamil and diltiazem]. Deutsche medizinische Wochenschrift (1946), 1985, Apr-26, Volume: 110, Issue:17 Topics: Calcium Channel Blockers; Coronary Disease; Diltiazem; Exercise Test; Heart Rate; Hemodynamics; Huma	1985
Hemodynamic effects of nifedipine given alone and in combination with atenolol in patients with impaired left ventricular function. The American journal of cardiology, 1985, May-17, Volume: 55, Issue:12 Topics: Administration, Oral; Adult; Angiography; Atenolol; Blood Pressure; Cardiac Catheterization; Cardiom	1985
Haemodynamic analysis of the effects of nicardipine and metoprolol alone and in combination in coronary artery disease. European heart journal, 1985, Volume: 6, Issue:11 Topics: Adult; Angina Pectoris; Calcium Channel Blockers; Coronary Disease; Drug Therapy, Combination; Femal	1985

nifedipine and Coronary Heart Disease

Research Excerpts

Research

Studies (733)

Authors

Clinical Trials (2)

Trial Overview

Reviews

Trials

Other Studies

Authors	Studies
Reiffen, M	1
Eberlein, W	1
Müller, P	3
Psiorz, M	1
Noll, K	1
Heider, J	1
Lillie, C	1
Kobinger, W	1
Luger, P	1
Tsuburaya, R	1
Takahashi, J	1
Nakamura, A	1
Nozaki, E	1
Sugi, M	1
Yamamoto, Y	1
Hiramoto, T	1
Horiguchi, S	1
Inoue, K	1
Goto, T	1
Kato, A	1
Shinozaki, T	1
Ishida, E	1
Miyata, S	1
Yasuda, S	2
Shimokawa, H	2
Sierra, C	1
Coca, A	1
Ji, H	1
Guo, WZ	1
Yan, ZH	1
Li, D	1
Lu, CL	1
Möllhoff, T	1
Schmidt, C	1
Van Aken, H	1
Berendes, E	1
Buerkle, H	1
Marmann, P	1
Reinbold, T	1
Prenger-Berninghoff, R	1