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nifedipine and Complications of Diabetes Mellitus

nifedipine has been researched along with Complications of Diabetes Mellitus in 22 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Research Excerpts

ExcerptRelevanceReference
"To investigate the impact of treatment on cardiovascular mortality and morbidity, we assessed outcomes in patients with hypertension and diabetes who received co-amilozide or nifedipine in the International Nifedipine GITS Study: Intervention as a Goal in Hypertension."9.10Outcomes with nifedipine GITS or Co-amilozide in hypertensive diabetics and nondiabetics in Intervention as a Goal in Hypertension (INSIGHT). ( Brown, M; Castaigne, A; de Leeuw, P; Mancia, G; Palmer, CR; Rosenthal, T; Ruilope, LM; Wagener, G, 2003)
"Randomised study of diabetic patients with microalbuminuria treated with perindopril or nifedipine for 12 months and monitored for one or three months after stopping treatment depending on whether they were hypertensive or normotensive."9.07Comparison between perindopril and nifedipine in hypertensive and normotensive diabetic patients with microalbuminuria. Melbourne Diabetic Nephropathy Study Group. ( , 1991)
" The Modern Approach to the Treatment of Hypertension (MATH) trial was conducted to determine the efficacy and safety of the new once-daily nifedipine gastrointestinal therapeutic system (GITS) formulation in a large cohort of mild-to-moderate hypertensive patients overall, and to identify specific effects of therapy in the presence of complicating factors such as diabetes and obesity."9.06Endocrine and renal effects of nifedipine gastrointestinal therapeutic system in patients with essential hypertension. Results of a multicenter trial. The Modern Approach to the Treatment of Hypertension Study Group. ( Bravo, EL; Friedman, CP; Krakoff, LR; Tuck, ML, 1990)
"We studied the incidence of oedema 2 weeks following initiation of nifedipine therapy for hypertension in a group of 10 diabetic subjects, and also measured skin blood flow (SBF) with a laser Doppler flowmeter, before and after lowering the foot."9.06Dependent oedema and attenuation of postural vasoconstriction associated with nifedipine therapy for hypertension in diabetic patients. ( Rayman, G; Tooke, JE; Williams, SA, 1989)
"It is generally agreed that short acting calcium channel blockers (CCB) as nifedipine are not safe as the reflex increase in sympathetic activity and thus, their use in hypertension (HTN) is questionable."7.73Treatment of complicated and uncomplicated hypertension with nifedipine in Palestine. ( Sweileh, WM, 2005)
"The results of a case-control study of 300 cataract patients and 609 controls indicate that long-term use of aspirin-like analgesics halves the risk of cataract."7.67Do aspirin-like analgesics protect against cataract? A case-control study. ( Harding, JJ; van Heyningen, R, 1986)
"To investigate the impact of treatment on cardiovascular mortality and morbidity, we assessed outcomes in patients with hypertension and diabetes who received co-amilozide or nifedipine in the International Nifedipine GITS Study: Intervention as a Goal in Hypertension."5.10Outcomes with nifedipine GITS or Co-amilozide in hypertensive diabetics and nondiabetics in Intervention as a Goal in Hypertension (INSIGHT). ( Brown, M; Castaigne, A; de Leeuw, P; Mancia, G; Palmer, CR; Rosenthal, T; Ruilope, LM; Wagener, G, 2003)
"The effects of nisoldipine and slow release nifedipine on mild to moderate hypertension and glycaemic control were studied in 28 diabetic hypertensives, all except one of whom were non-insulin dependent."5.07Nifedipine and nisoldipine in hypertensive diabetics. ( Clarke, CW; Kubik, MM, 1991)
"Randomised study of diabetic patients with microalbuminuria treated with perindopril or nifedipine for 12 months and monitored for one or three months after stopping treatment depending on whether they were hypertensive or normotensive."5.07Comparison between perindopril and nifedipine in hypertensive and normotensive diabetic patients with microalbuminuria. Melbourne Diabetic Nephropathy Study Group. ( , 1991)
" The Modern Approach to the Treatment of Hypertension (MATH) trial was conducted to determine the efficacy and safety of the new once-daily nifedipine gastrointestinal therapeutic system (GITS) formulation in a large cohort of mild-to-moderate hypertensive patients overall, and to identify specific effects of therapy in the presence of complicating factors such as diabetes and obesity."5.06Endocrine and renal effects of nifedipine gastrointestinal therapeutic system in patients with essential hypertension. Results of a multicenter trial. The Modern Approach to the Treatment of Hypertension Study Group. ( Bravo, EL; Friedman, CP; Krakoff, LR; Tuck, ML, 1990)
"We studied the incidence of oedema 2 weeks following initiation of nifedipine therapy for hypertension in a group of 10 diabetic subjects, and also measured skin blood flow (SBF) with a laser Doppler flowmeter, before and after lowering the foot."5.06Dependent oedema and attenuation of postural vasoconstriction associated with nifedipine therapy for hypertension in diabetic patients. ( Rayman, G; Tooke, JE; Williams, SA, 1989)
"It is generally agreed that short acting calcium channel blockers (CCB) as nifedipine are not safe as the reflex increase in sympathetic activity and thus, their use in hypertension (HTN) is questionable."3.73Treatment of complicated and uncomplicated hypertension with nifedipine in Palestine. ( Sweileh, WM, 2005)
"The results of a case-control study of 300 cataract patients and 609 controls indicate that long-term use of aspirin-like analgesics halves the risk of cataract."3.67Do aspirin-like analgesics protect against cataract? A case-control study. ( Harding, JJ; van Heyningen, R, 1986)
"Long-acting nifedipine tablets were given to 47 severely and moderately hypertensive patients with renal insufficiency, cardiovascular, cerebrovascular, and peripheral vascular disease, diabetes mellitus, asthma, and systemic lupus erythematosus."3.67Long-acting nifedipine in moderate and severe hypertensive patients with serious concomitant diseases. ( Bursztyn, M; Grossman, E; Rosenthal, T, 1985)
"Atenolol treatment significantly increased triglyceride levels and decreased the HDL-cholesterol levels after 9 months in both groups."2.68Comparative effects of atenolol versus nifedipine on serum lipids and other biochemical parameters in diabetic and non-diabetic hypertensive subjects. ( Goyal, RK; Satia, MC; Shukla, ML, 1995)
"Nifedipine, a dihydropyridine calcium antagonist, improves endothelial function in patients with hypercholesterolaemia by enhancing nitric oxide (NO) activity, and increases endothelial NO bioavailability by antioxidant mechanisms."1.34Effect of nifedipine on adiponectin in hypertensive patients with type 2 diabetes mellitus. ( Inami, N; Iwasaka, T; Kimura, Y; Nishikawa, M; Nomura, S; Omoto, S; Shouzu, A, 2007)
"Nifedipine was the most frequently prescribed antihypertensive (44."1.32Inadequate control of blood pressure in Nigerians with diabetes. ( Okoro, EO; Oyejola, BA, 2004)
"1."1.28Pharmacological studies of human erectile tissue: characteristics of spontaneous contractions and alterations in alpha-adrenoceptor responsiveness with age and disease in isolated tissues. ( Christ, GJ; Maayani, S; Melman, A; Valcic, M, 1990)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19904 (18.18)18.7374
1990's10 (45.45)18.2507
2000's6 (27.27)29.6817
2010's2 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stojanović, M1
Prostran, M1
Janković, R1
Radenković, M1
Kobayashi, N1
Ishimitsu, T1
Mancia, G1
Brown, M1
Castaigne, A1
de Leeuw, P1
Palmer, CR1
Rosenthal, T2
Wagener, G1
Ruilope, LM1
Fuchs, FD1
Okoro, EO1
Oyejola, BA1
Sweileh, WM1
Nomura, S1
Inami, N1
Kimura, Y1
Omoto, S1
Shouzu, A1
Nishikawa, M1
Iwasaka, T1
Io, K1
Minatoguchi, S1
Nishigaki, K1
Ojio, S1
Tanaka, T1
Segawa, T1
Matsuo, H1
Watanabe, S1
Hattori, A1
Ueno, K1
Ono, H1
Hiei, K1
Sato, H1
Morita, N1
Noda, T1
Kato, T1
Kawasaki, M1
Takemura, G1
Fujiwara, H1
Cicco, G1
Pirrelli, A1
Satia, MC1
Shukla, ML1
Goyal, RK1
Motro, M1
Shemesh, J1
Robles, NR1
Gill, J1
Fonseca, V1
Dandona, P1
Jeremy, JY1
Christ, GJ1
Maayani, S1
Valcic, M1
Melman, A1
Ferder, L1
Daccordi, H1
Martello, M1
Panzalis, M1
Inserra, F1
Clarke, CW1
Kubik, MM1
Tuck, ML1
Bravo, EL1
Krakoff, LR1
Friedman, CP1
Williams, SA1
Rayman, G1
Tooke, JE1
van Heyningen, R1
Harding, JJ1
Benaim, ME1
Macdonald, G1
Bursztyn, M1
Grossman, E1

Trials

9 trials available for nifedipine and Complications of Diabetes Mellitus

ArticleYear
Outcomes with nifedipine GITS or Co-amilozide in hypertensive diabetics and nondiabetics in Intervention as a Goal in Hypertension (INSIGHT).
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:3

    Topics: Aged; Amiloride; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiovascular D

2003
Comparative effects of atenolol versus nifedipine on serum lipids and other biochemical parameters in diabetic and non-diabetic hypertensive subjects.
    Indian journal of physiology and pharmacology, 1995, Volume: 39, Issue:3

    Topics: Aged; Antihypertensive Agents; Atenolol; Blood Glucose; Blood Pressure; Blood Urea Nitrogen; Creatin

1995
Lisinopril and nifedipine administration inhibits the ex vivo uptake of [45Ca2+] by platelets from hypertensive diabetic patients.
    British journal of clinical pharmacology, 1992, Volume: 33, Issue:2

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Platelets; Bucladesine; Calcium; Diabet

1992
Angiotensin converting enzyme inhibitors versus calcium antagonists in the treatment of diabetic hypertensive patients.
    Hypertension (Dallas, Tex. : 1979), 1992, Volume: 19, Issue:2 Suppl

    Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Creatinine; Diab

1992
Nifedipine and nisoldipine in hypertensive diabetics.
    Journal of human hypertension, 1991, Volume: 5, Issue:6

    Topics: Adult; Aged; Blood Glucose; Blood Pressure; Diabetes Complications; Diabetes Mellitus; Humans; Hyper

1991
Comparison between perindopril and nifedipine in hypertensive and normotensive diabetic patients with microalbuminuria. Melbourne Diabetic Nephropathy Study Group.
    BMJ (Clinical research ed.), 1991, Jan-26, Volume: 302, Issue:6770

    Topics: Adolescent; Adult; Aged; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diab

1991
Endocrine and renal effects of nifedipine gastrointestinal therapeutic system in patients with essential hypertension. Results of a multicenter trial. The Modern Approach to the Treatment of Hypertension Study Group.
    American journal of hypertension, 1990, Volume: 3, Issue:12 Pt 2

    Topics: Aged; Blood Pressure; Diabetes Complications; Electrolytes; Endocrine Glands; Female; Heart Rate; He

1990
Dependent oedema and attenuation of postural vasoconstriction associated with nifedipine therapy for hypertension in diabetic patients.
    European journal of clinical pharmacology, 1989, Volume: 37, Issue:4

    Topics: Adult; Aged; Clinical Trials as Topic; Diabetes Complications; Edema; Female; Humans; Hypertension;

1989
Effect of nifedipine on carbohydrate metabolism and serum lipoproteins in hypertensive patients with and without diabetes mellitus.
    European heart journal, 1987, Volume: 8 Suppl K

    Topics: Adult; Aged; Blood Pressure; Carbohydrate Metabolism; Diabetes Complications; Diabetes Mellitus; Fem

1987

Other Studies

13 other studies available for nifedipine and Complications of Diabetes Mellitus

ArticleYear
Clarification of serotonin-induced effects in peripheral artery disease observed through the femoral artery response in models of diabetes and vascular occlusion: The role of calcium ions.
    Clinical and experimental pharmacology & physiology, 2017, Volume: 44, Issue:7

    Topics: Animals; Calcium; Diabetes Complications; Disease Models, Animal; Femoral Artery; Nifedipine; Ouabai

2017
Assessment on antihypertensive effect and safety of nifedipine controlled-release tablet administered at 80 mg/day in practical clinic.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2012, Volume: 34, Issue:3

    Topics: Adult; Age Factors; Aged; Ambulatory Care Facilities; Amlodipine; Antihypertensive Agents; Blood Pre

2012
May we die twice?
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 42, Issue:3

    Topics: Amiloride; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Diabetes Complications

2003
Inadequate control of blood pressure in Nigerians with diabetes.
    Ethnicity & disease, 2004,Winter, Volume: 14, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Care Facilities; Angiotensin-Converting Enzym

2004
Treatment of complicated and uncomplicated hypertension with nifedipine in Palestine.
    Saudi medical journal, 2005, Volume: 26, Issue:1

    Topics: Calcium Channel Blockers; Diabetes Complications; Female; Humans; Hypertension; Male; Middle East; N

2005
Effect of nifedipine on adiponectin in hypertensive patients with type 2 diabetes mellitus.
    Journal of human hypertension, 2007, Volume: 21, Issue:1

    Topics: Adiponectin; Aged; Biomarkers; Calcium Channel Blockers; Diabetes Complications; Diabetes Mellitus,

2007
Effects of benidipine and some other calcium channel blockers on the prognosis of patients with vasospastic angina. Cohort study with evaluation of the ergonovine coronary spasm induction test.
    Arzneimittel-Forschung, 2007, Volume: 57, Issue:9

    Topics: Adult; Aged; Aging; Amlodipine; Angina Pectoris; Calcium Channel Blockers; Cohort Studies; Coronary

2007
[Glyco-lipid changes in hypertensive diabetic patients undergoing treatment with nifedipine and captopril].
    Minerva medica, 1993, Volume: 84, Issue:3

    Topics: Adult; Blood Glucose; Captopril; Cholesterol; Diabetes Complications; Diabetes Mellitus; Follow-Up S

1993
Prevalence of coronary calcification in relation to age, gender and risk factor profile in the insight population.
    British journal of clinical practice. Supplement, 1997, Volume: 88

    Topics: Calcinosis; Calcium Channel Blockers; Coronary Angiography; Coronary Disease; Diabetes Complications

1997
[New central agents in the treatment of arterial hypertension].
    Anales de medicina interna (Madrid, Spain : 1984), 1999, Volume: 16, Issue:10

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Adult; Antihyp

1999
Pharmacological studies of human erectile tissue: characteristics of spontaneous contractions and alterations in alpha-adrenoceptor responsiveness with age and disease in isolated tissues.
    British journal of pharmacology, 1990, Volume: 101, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Do aspirin-like analgesics protect against cataract? A case-control study.
    Lancet (London, England), 1986, May-17, Volume: 1, Issue:8490

    Topics: Acetaminophen; Aged; Analgesics; Aspirin; Cataract; Diabetes Complications; Epidemiologic Methods; F

1986
Long-acting nifedipine in moderate and severe hypertensive patients with serious concomitant diseases.
    American heart journal, 1985, Volume: 110, Issue:1 Pt 1

    Topics: Adult; Aged; Angina Pectoris; Asthma; Cerebrovascular Disorders; Diabetes Complications; Edema; Fema

1985