nifedipine has been researched along with Cognition Disorders in 9 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We compared the effects of nilvadipine and amlodipine on the cognitive function and regional cerebral blood flow (rCBF) in patients with mild cognitive impairment (MCI) and hypertension." | 5.12 | Favourable effects of nilvadipine on cognitive function and regional cerebral blood flow on SPECT in hypertensive patients with mild cognitive impairment. ( Abe, K; Hanyu, H; Hirao, K; Iwamoto, T; Koizumi, K; Shimizu, S, 2007) |
| "Nifedipine treatment decreased serum insulin level to one fifth of that in KK-A(y) mice without nifedipine." | 1.35 | Diabetes-associated cognitive impairment is improved by a calcium channel blocker, nifedipine. ( Fujita, T; Horiuchi, M; Iwai, M; Iwanami, J; Li, JM; Min, LJ; Mogi, M; Sakata, A; Tsukuda, K, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Heus, RAA | 1 |
| Olde Rikkert, MGM | 1 |
| Tully, PJ | 1 |
| Lawlor, BA | 1 |
| Claassen, JAHR | 1 |
| Baev, VM | 1 |
| Kozlov, DB | 1 |
| Berezan, MIu | 1 |
| Lovell, MA | 1 |
| Abner, E | 1 |
| Kryscio, R | 1 |
| Xu, L | 1 |
| Fister, SX | 1 |
| Lynn, BC | 1 |
| Jain, S | 1 |
| Sharma, BM | 1 |
| Sharma, B | 1 |
| Yang, CH | 1 |
| Huang, CC | 1 |
| Hsu, KS | 1 |
| Dudley, JA | 1 |
| Weir, RK | 1 |
| Yan, TC | 1 |
| Grabowska, EM | 1 |
| Grimmé, AJ | 1 |
| Amini, S | 1 |
| Stephens, DN | 1 |
| Hunt, SP | 1 |
| Stanford, SC | 1 |
| Hanyu, H | 2 |
| Hirao, K | 2 |
| Shimizu, S | 2 |
| Iwamoto, T | 2 |
| Koizumi, K | 1 |
| Abe, K | 1 |
| Sato, T | 1 |
| Kiuchi, A | 1 |
| Tsukuda, K | 1 |
| Mogi, M | 1 |
| Li, JM | 1 |
| Iwanami, J | 1 |
| Min, LJ | 1 |
| Sakata, A | 1 |
| Fujita, T | 1 |
| Iwai, M | 1 |
| Horiuchi, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A European Multicentre Double-blind Placebo-controlled Phase III Trial of Nilvadipine in Mild to Moderate Alzheimer's Disease[NCT02017340] | Phase 3 | 511 participants (Actual) | Interventional | 2013-04-24 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for nifedipine and Cognition Disorders
| Article | Year |
|---|---|
Blood Pressure Variability and Progression of Clinical Alzheimer Disease.
Topics: Aged; Alzheimer Disease; Antihypertensive Agents; Blood Pressure Determination; Cognition Disorders; | 2019 |
[Cognitive functions and extracranial circulation in patients with hypertonic crisis].
Topics: Adult; Antihypertensive Agents; Cognition Disorders; Enalapril; Female; Humans; Hypertensive Encepha | 2013 |
Favourable effects of nilvadipine on cognitive function and regional cerebral blood flow on SPECT in hypertensive patients with mild cognitive impairment.
Topics: Aged; Amlodipine; Antihypertensive Agents; Brain; Cerebrovascular Circulation; Cognition Disorders; | 2007 |
Nilvadipine prevents cognitive decline of patients with mild cognitive impairment.
Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Cognition Disorders; D | 2007 |
5 other studies available for nifedipine and Cognition Disorders
| Article | Year |
|---|---|
Calcium Channel Blockers, Progression to Dementia, and Effects on Amyloid Beta Peptide Production.
Topics: Aged; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Antihypertensive Agents; Apolipoprotein | 2015 |
Calcium Channel Blockade and Peroxisome Proliferator Activated Receptor γ Agonism Diminish Cognitive Loss and Preserve Endothelial Function During Diabetes Mellitus.
Topics: Animals; Attention; Blood-Brain Barrier; Brain; Calcium Channel Blockers; Calcium Channels; Capillar | 2016 |
A critical role for protein tyrosine phosphatase nonreceptor type 5 in determining individual susceptibility to develop stress-related cognitive and morphological changes.
Topics: Aggression; Analysis of Variance; Animals; Biophysics; Brain; Calcium Channel Blockers; Cell Line, T | 2012 |
Antagonism of L-type Ca(v) channels with nifedipine differentially affects performance of wildtype and NK1R-/- mice in the 5-Choice Serial Reaction-Time Task.
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Calcium Channel Blockers; | 2013 |
Diabetes-associated cognitive impairment is improved by a calcium channel blocker, nifedipine.
Topics: Animals; Brain; Calcium Channel Blockers; Cerebrovascular Circulation; Cognition; Cognition Disorder | 2008 |