Page last updated: 2024-11-01

nifedipine and Chilblains

nifedipine has been researched along with Chilblains in 8 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Chilblains: Recurrent localized itching, swelling and painful erythema on the fingers, toes or ears, produced by exposure to cold.

Research Excerpts

ExcerptRelevanceReference
"Nifedipine is commonly prescribed for the treatment of chilblains (pernio, perniosis) on the basis of observational studies and a single small, older clinical trial."9.22Nifedipine vs Placebo for Treatment of Chronic Chilblains: A Randomized Controlled Trial. ( Bor, JH; Lagro-Janssen, AL; Smits, P; Souwer, IH, 2016)
"Nifedipine is commonly prescribed for the treatment of chilblains (pernio, perniosis) on the basis of observational studies and a single small, older clinical trial."5.22Nifedipine vs Placebo for Treatment of Chronic Chilblains: A Randomized Controlled Trial. ( Bor, JH; Lagro-Janssen, AL; Smits, P; Souwer, IH, 2016)
"Idiopathic chilblains is a cold-induced inflammatory condition that causes significant morbidity."2.72Pharmacologic Treatment of Idiopathic Chilblains (Pernio): A Systematic Review. ( Kirchhof, MG; Mahmood, F; Pratt, M, 2021)
"She was diagnosed with pernio and successfully treated, initially with nifedipine and subsequently with management of the affected area's environment."1.31Erythrocyanotic discoloration of the toes. ( Parlette, EC; Parlette, HL, 2000)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's1 (12.50)18.2507
2000's2 (25.00)29.6817
2010's1 (12.50)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Pratt, M1
Mahmood, F1
Kirchhof, MG1
Zhou, Y1
Yan, H1
Li, T1
Xie, M1
Li, X1
Zhao, C1
Souwer, IH1
Bor, JH1
Smits, P1
Lagro-Janssen, AL1
Hedrich, CM1
Fiebig, B1
Hauck, FH1
Sallmann, S1
Hahn, G1
Pfeiffer, C1
Heubner, G1
Lee-Kirsch, MA1
Gahr, M1
Parlette, EC1
Parlette, HL1
Goette, DK1
Rustin, MH2
Newton, JA1
Smith, NP1
Dowd, PM2
Lanigan, S1

Reviews

2 reviews available for nifedipine and Chilblains

ArticleYear
Pharmacologic Treatment of Idiopathic Chilblains (Pernio): A Systematic Review.
    Journal of cutaneous medicine and surgery, 2021, Volume: 25, Issue:5

    Topics: Chilblains; Humans; Nifedipine; Pentoxifylline; Vasodilator Agents

2021
Chilblain lupus erythematosus--a review of literature.
    Clinical rheumatology, 2008, Volume: 27, Issue:8

    Topics: Administration, Topical; Adolescent; Calcium Channel Blockers; Chilblains; Exodeoxyribonucleases; Ge

2008

Trials

3 trials available for nifedipine and Chilblains

ArticleYear
Nifedipine vs Placebo for Treatment of Chronic Chilblains: A Randomized Controlled Trial.
    Annals of family medicine, 2016, Volume: 14, Issue:5

    Topics: Administration, Oral; Adult; Aged; Blood Pressure; Calcium Channel Blockers; Chilblains; Chronic Dis

2016
The treatment of chilblains with nifedipine: the results of a pilot study, a double-blind placebo-controlled randomized study and a long-term open trial.
    The British journal of dermatology, 1989, Volume: 120, Issue:2

    Topics: Adolescent; Adult; Aged; Chilblains; Clinical Trials as Topic; Double-Blind Method; Female; Frostbit

1989
Nifedipine in the treatment of chilblains.
    British medical journal (Clinical research ed.), 1986, Oct-11, Volume: 293, Issue:6552

    Topics: Chilblains; Clinical Trials as Topic; Double-Blind Method; Frostbite; Humans; Nifedipine; Random All

1986

Other Studies

3 other studies available for nifedipine and Chilblains

ArticleYear
New use of old medicine: Nifedipine acts on the TRP family and inflammatory proteins in the treatment of chilblain.
    Burns : journal of the International Society for Burn Injuries, 2022, Volume: 48, Issue:2

    Topics: Animals; Burns; Chilblains; Humans; Interleukin-6; Nifedipine; Rats; Rats, Sprague-Dawley; Tumor Nec

2022
Erythrocyanotic discoloration of the toes.
    Cutis, 2000, Volume: 65, Issue:4

    Topics: Adult; Chilblains; Female; Foot Diseases; Humans; Nifedipine; Physical Therapy Modalities; Toes

2000
Chilblains (perniosis).
    Journal of the American Academy of Dermatology, 1990, Volume: 23, Issue:2 Pt 1

    Topics: Adult; Aged; Aged, 80 and over; Chilblains; Child; Diagnosis, Differential; Female; Humans; Lymphocy

1990