Page last updated: 2024-11-01

nifedipine and Chagas Disease

nifedipine has been researched along with Chagas Disease in 5 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Chagas Disease: Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON.

Research Excerpts

ExcerptRelevanceReference
"The effects of sublingual nifedipine and isosorbide dinitrate on oesophageal emptying were compared in 11 patients with Chagasic achalasia."9.07Short report: comparison of the effects of sublingual nifedipine and isosorbide dinitrate on oesophageal emptying in patients with Chagasic achalasia. ( Figueiredo, MC; Iazigi, N; Matsuda, NM; Oliveira, RB, 1992)
"The effects of sublingual nifedipine and isosorbide dinitrate on oesophageal emptying were compared in 11 patients with Chagasic achalasia."5.07Short report: comparison of the effects of sublingual nifedipine and isosorbide dinitrate on oesophageal emptying in patients with Chagasic achalasia. ( Figueiredo, MC; Iazigi, N; Matsuda, NM; Oliveira, RB, 1992)
"Chagas disease is a neglected tropical disease."2.58Isosorbide and nifedipine for Chagas' megaesophagus: A systematic review and meta-analysis. ( Borges Migliavaca, C; Colpani, V; Falavigna, M; Nascimento Cruz, L; Oliveira Dantas, R; René Pinto de Sousa Miguel, S; Stein, C, 2018)
"Nifedipine treated mice behaved as controls."1.30GM1 ganglioside induced myocardial restoration and survival of mice with experimental Chagas' disease. ( Bronia, DH; Cossy Isasi, S; Fernandez, AR; Paglini, P, 1999)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Borges Migliavaca, C1
Stein, C1
Colpani, V1
René Pinto de Sousa Miguel, S1
Nascimento Cruz, L1
Oliveira Dantas, R1
Falavigna, M1
Sbaraglini, ML1
Bellera, CL1
Fraccaroli, L1
Larocca, L1
Carrillo, C1
Talevi, A1
Alba Soto, CD1
Cossy Isasi, S1
Fernandez, AR1
Paglini, P1
Bronia, DH1
Figueiredo, MC1
Oliveira, RB2
Iazigi, N1
Matsuda, NM1
Dantas, RO1
Godoy, RA1
Villanova, MG1
Meneghelli, UG1
Troncon, LE1

Reviews

1 review available for nifedipine and Chagas Disease

ArticleYear
Isosorbide and nifedipine for Chagas' megaesophagus: A systematic review and meta-analysis.
    PLoS neglected tropical diseases, 2018, Volume: 12, Issue:9

    Topics: Adolescent; Adult; Aged; Chagas Disease; Esophageal Achalasia; Female; Humans; Isosorbide; Male; Mid

2018

Trials

1 trial available for nifedipine and Chagas Disease

ArticleYear
Short report: comparison of the effects of sublingual nifedipine and isosorbide dinitrate on oesophageal emptying in patients with Chagasic achalasia.
    Alimentary pharmacology & therapeutics, 1992, Volume: 6, Issue:4

    Topics: Administration, Sublingual; Adult; Aged; Chagas Disease; Esophageal Achalasia; Esophagus; Female; Hu

1992

Other Studies

3 other studies available for nifedipine and Chagas Disease

ArticleYear
Novel cruzipain inhibitors for the chemotherapy of chronic Chagas disease.
    International journal of antimicrobial agents, 2016, Volume: 48, Issue:1

    Topics: Adult; Animals; Antiprotozoal Agents; Chagas Disease; Chronic Disease; Clofazimine; Cysteine Endopep

2016
GM1 ganglioside induced myocardial restoration and survival of mice with experimental Chagas' disease.
    Acta tropica, 1999, Oct-15, Volume: 73, Issue:3

    Topics: Animals; Calcium Channel Blockers; Chagas Cardiomyopathy; Chagas Disease; Electrocardiography; G(M1)

1999
Effect of nifedipine on the lower esophageal sphincter pressure in chagasic patients.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1986, Volume: 19, Issue:2

    Topics: Adult; Chagas Disease; Esophagogastric Junction; Female; Humans; Male; Manometry; Middle Aged; Nifed

1986