nifedipine has been researched along with Carotid Stenosis in 9 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Carotid Stenosis: Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Effects of metoprolol, nifedipine, and captopril were studied, by quantitative spectral analysis, in 20 patients with carotid stenosis to evaluate 3 indices of disturbed flow: peak velocity, spectral broadening index and window index (WI)." | 9.07 | Effects of antihypertensive drugs on flow disturbances: nifedipine, captopril, and metoprolol evaluated by quantitative spectral analysis of Doppler flow patterns in patients with carotid stenosis. ( Spence, JD, 1994) |
| "To evaluate the effect of a calcium antagonist, nilvadipine, on cerebral blood flow and oxygen metabolism, we prospectively examined five ischaemic stroke patients, with both hypertension and chronic major cerebral artery occlusion, using positron emission tomography." | 5.10 | Effect of calcium antagonist on cerebral blood flow and oxygen metabolism in patients with hypertension and chronic major cerebral artery occlusion: a positron emission tomography study. ( Kobayashi, M; Noda, A; Ogasawara, K; Ogawa, A; Yasuda, S; Yukawa, H, 2003) |
| "This study, ancillary to the International Nifedipine GITS Study: Intervention as a Goal in Hypertension Treatment (INSIGHT), involved nifedipine 30 mg or co-amilozide (hydrochlorothiazide 25 mg and amiloride 2." | 5.09 | Differential effects of nifedipine and co-amilozide on the progression of early carotid wall changes. ( Gariépy, J; Levenson, J; Moyse, D; Simon, A, 2001) |
| " Effects of metoprolol, nifedipine, and captopril were studied, by quantitative spectral analysis, in 20 patients with carotid stenosis to evaluate 3 indices of disturbed flow: peak velocity, spectral broadening index and window index (WI)." | 5.07 | Effects of antihypertensive drugs on flow disturbances: nifedipine, captopril, and metoprolol evaluated by quantitative spectral analysis of Doppler flow patterns in patients with carotid stenosis. ( Spence, JD, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (55.56) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ogasawara, K | 1 |
| Noda, A | 1 |
| Yasuda, S | 1 |
| Kobayashi, M | 1 |
| Yukawa, H | 1 |
| Ogawa, A | 1 |
| Gariepy, J | 2 |
| Simon, A | 2 |
| Chironi, G | 1 |
| Moyse, D | 2 |
| Levenson, J | 2 |
| Zhang, QG | 1 |
| Xu, YL | 1 |
| Li, HC | 1 |
| Han, D | 1 |
| Zhang, GY | 1 |
| Akopov, SS | 1 |
| Grigorian, GS | 1 |
| Gabrielian, ES | 1 |
| Spence, JD | 1 |
| Akopov, S | 1 |
| Grigorian, G | 1 |
| Gabrielian, E | 1 |
| Winterkorn, JM | 1 |
| Kupersmith, MJ | 1 |
| Wirtschafter, JD | 1 |
| Forman, S | 1 |
| Udotova, SA | 1 |
| Proskurin, VV | 1 |
| Martynov, IuS | 1 |
| Ivleva, AIa | 1 |
| Lepakhin, VK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A European Multicentre Double-blind Placebo-controlled Phase III Trial of Nilvadipine in Mild to Moderate Alzheimer's Disease[NCT02017340] | Phase 3 | 511 participants (Actual) | Interventional | 2013-04-24 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 trials available for nifedipine and Carotid Stenosis
| Article | Year |
|---|---|
Effect of calcium antagonist on cerebral blood flow and oxygen metabolism in patients with hypertension and chronic major cerebral artery occlusion: a positron emission tomography study.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Carotid Stenosis; Cerebrovascular Circulation; Femal | 2003 |
Large artery wall thickening and its determinants under antihypertensive treatment: the IMT-INSIGHT study.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Benzothiadiazines; Calcium Channel Blockers; Carot | 2004 |
Effects of antihypertensive drugs on flow disturbances: nifedipine, captopril, and metoprolol evaluated by quantitative spectral analysis of Doppler flow patterns in patients with carotid stenosis.
Topics: Aged; Blood Pressure; Captopril; Cardiac Output; Carotid Stenosis; Cross-Over Studies; Double-Blind | 1994 |
Differential effects of nifedipine and co-amilozide on the progression of early carotid wall changes.
Topics: Aged; Aged, 80 and over; Amiloride; Antihypertensive Agents; Atenolol; Blood Pressure; Carotid Arter | 2001 |
[Calcium antagonists in the treatment of cerebrovascular diseases].
Topics: Adult; Aged; Brain Ischemia; Carotid Artery, Internal; Carotid Stenosis; Cerebrovascular Circulation | 1992 |
4 other studies available for nifedipine and Carotid Stenosis
| Article | Year |
|---|---|
NMDA receptor/L-VGCC-dependent expression and AMPA/KA receptor-dependent activation of c-Jun induced by cerebral ischemia in rat hippocampus.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Carotid Stenosis; Enzyme Activation; Hi | 2006 |
Dynamic component of internal carotid artery stenosis in patients with cerebrovascular disease: effects of nifedipine.
Topics: Aged; Blood Flow Velocity; Carotid Artery, Internal; Carotid Stenosis; Cerebrovascular Circulation; | 1994 |
Noninvasive testing of dynamic component of internal carotid artery stenosis in patients with chronic cerebrovascular disease.
Topics: Brain; Carotid Artery, Common; Carotid Artery, Internal; Carotid Stenosis; Cerebrovascular Disorders | 1994 |
Brief report: treatment of vasospastic amaurosis fugax with calcium-channel blockers.
Topics: Adult; Aged; Blindness; Carotid Stenosis; Embolism; Female; Humans; Male; Middle Aged; Nifedipine; R | 1993 |