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nifedipine and Cardiovascular Pregnancy Complications

nifedipine has been researched along with Cardiovascular Pregnancy Complications in 95 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Research Excerpts

ExcerptRelevanceReference
"To assess the maternal and fetal outcome in women with mild to moderate chronic hypertension on antihypertensive drug (methyldopa or nifedipine) therapy compared to no medication."9.30Methyldopa versus nifedipine or no medication for treatment of chronic hypertension during pregnancy: A multicenter randomized clinical trial. ( Abdallah, S; Gaber, W; Gamal, A; Hamza, H; Marawan, H; Rezk, M; Salama, M, 2019)
" Methyldopa, labetalol, and nifedipine have been perceived safe to use during pregnancy and are therefore recommended in international guidelines for treatment of hypertension."9.22Pharmacokinetics of the most commonly used antihypertensive drugs throughout pregnancy methyldopa, labetalol, and nifedipine: a systematic review. ( Allegaert, K; Flint, RB; Mian, P; Schoenmakers, S; van de Vusse, D; Versmissen, J; Visser, W, 2022)
"Sixty-four women in the second half of pregnancy who were not in labor randomly received 10 mg nifedipine tablets (n = 55 studies) or 10 mg nifedipine capsules (n = 74 studies) if blood pressure was > or =170/110 mm Hg."9.10Efficacy and safety of nifedipine tablets for the acute treatment of severe hypertension in pregnancy. ( Brown, MA; Buddle, ML; Davis, GK; Farrell, T, 2002)
"To determine the efficacy of Nifedipine on postpartum blood Loss in patients with Pregnancy Induced Hypertension (PIH)."9.09[The effect of Nifedipine on postpartum blood loss in patients with pregnancy induced hypertension]. ( Liu, Y; Yang, X, 2000)
"We sought to compare the efficacies of oral nifedipine and intravenous labetalol in the acute management of hypertensive emergencies of pregnancy."9.09A randomized, double-blind trial of oral nifedipine and intravenous labetalol in hypertensive emergencies of pregnancy. ( Chauhan, SP; Newman, RB; Scardo, JA; Vermillion, ST, 1999)
"The safety of use of the calcium channel blocker nifedipine in pregnancy as it affects child development has not been well evaluated."9.09Nifedipine administered in pregnancy: effect on the development of children at 18 months. ( Bortolus, R; Chatenoud, L; Parazzini, F; Ricci, E, 2000)
"To determine whether nifedipine or prazosin is the more appropriate second-line antihypertensive agent in pregnancy."9.09Nifedipine or prazosin as a second agent to control early severe hypertension in pregnancy: a randomised controlled trial. ( Hall, DR; Odendaal, HJ; Smith, M; Steyn, DW, 2000)
"To compare the effect of routine treatment with the calcium channel blocker nifedipine in mild to moderate hypertension in pregnancy."9.08Nifedipine versus expectant management in mild to moderate hypertension in pregnancy. Gruppo di Studio Ipertensione in Gravidanza. ( , 1998)
"Sublingual nifedipine was comparable to IV hydrallazine in the treatment of acute hypertension of pregnancy."9.08Sublingual nifedipine compared with intravenous hydrallazine in the acute treatment of severe hypertension in pregnancy: potential for use in rural practice. ( Jegasothy, R; Paranthaman, S, 1996)
"Thirty women with pregnancy-induced hypertension (PIH) scheduled for Caesarean section under general anaesthesia were studied to evaluate the efficacy of sublingual nifedipine in attenuating the pressor response to laryngoscopy and tracheal intubation."9.07Nifedipine attenuates the hypertensive response to tracheal intubation in pregnancy-induced hypertension. ( Bala, I; Batra, YK; Gopalan, S; Kumar, N, 1993)
"To compare nifedipine (group 1) with methyldopa (group 2) in the management of pregnancy induced hypertension (PIH)."9.07A comparison of nifedipine with methyldopa in pregnancy induced hypertension. ( Jayawardana, J; Lekamge, N, 1994)
"The effect of nifedipine on uteroplacental blood flow was investigated in nine hypertensive women in the trimester of pregnancy and compared with the effects of a placebo in nine similar hypertensive women."9.06The effect of sublingual nifedipine on uteroplacental blood flow in hypertensive pregnancy. ( Davey, DA; Davies, N; Lindow, SW; Smith, JA, 1988)
"The effect of nifedipine (Adalat; Bayer-Miles)--a calcium channel blocker, which has a well-established place in nonobstetric hypertension--was compared with dihydralazine in 33 primigravidas with severe hypertension of pregnancy."9.06Nifedipine in acute hypertensive emergencies in pregnancy. ( Becker, P; Moodley, J; Seabe, SJ, 1989)
"Oral nifedipine is recommended along with labetalol and hydralazine for treatment of severe hypertension during pregnancy by most authorities."8.93Oral nifedipine versus intravenous labetalol for severe hypertension during pregnancy: a systematic review and meta-analysis. ( Gupta, N; Kirubakaran, R; Pareek, P; Shekhar, S, 2016)
"The primary outcome indicators included the safety and antihypertensive efficacy of nifedipine in pregnancy; the effects of nifedipine on maternal/fetal hemodynamics; and the effect, if any, of nifedipine on perinatal outcome."8.79Use of nifedipine in the hypertensive diseases of pregnancy. ( Doering, PL; Hatton, RC; Levin, AC, 1994)
"Alpha-methyldopa is a regularly used antihypertensive drug during pregnancy."7.76[Methyldopa-induced acute reactive hepatitis in pregnancy, drug-metabolizing capacity of the liver]. ( Monostory, K; Ozsvár, Z; Solymossi, Z, 2010)
"Study aim was assessment of clinical efficacy of mono therapy with nifedipine SR/GITS and combination of nifedipine SR/GITS and bisoprolol as well as investigation of functional state of sympathoadrenal system (SAS) in pregnant women with arterial hypertension."7.74[Clinical efficacy of antihypertensive therapy of pregnant women with arterial hypertension with long acting nifedipine and bisoprolol]. ( Brytkova, IaV; Bukhonkina, IuM; Pavlova, LN; Striuk, RI, 2008)
"To investigate the effect of 7 to 14 days of therapy with nifedipine (sustained-release preparation) on the 24-hour blood pressure patterns of pregnant women with pre-eclampsia or chronic hypertension, and to test the utility of blood pressure monitoring in modulating the timing and dosage of the drug."7.6924-hour blood pressure monitoring to evaluate the effects of nifedipine in pre-eclampsia and in chronic hypertension in pregnancy. ( Benedetto, C; Carandente, F; Chiarolini, L; Giarola, M; Maulà, V; Zonca, M, 1997)
" Description of their management, usage of nifedipine, and pregnancy outcome."7.69Sublingual nifedipine in human pregnancy. ( Gallery, ED; Györy, AZ, 1997)
"Nifedipine was administered to 49 pregnant women with gestational hypertension as first-line therapy, and were longitudinally studied as paired observations for 3 or 10 day intervals of treatment with nifedipine until delivery."7.69The use of nifedipine as first-line hypotensive therapy in gestational hypertension. ( Caruso, A; De Carolis, MP; De Carolis, S; Ferrazzani, S; Mancinelli, S; Romano, D, 1994)
"The effect of lowering the maternal blood pressure with sublingual nifedipine on the fetal heart rate was studied in 51 patients with severe pregnancy-induced hypertension."7.68Effect of nifedipine on fetal heart rate in the treatment of severe pregnancy-induced hypertension. ( Fenakel, K; Friedman, A; Lurie, S, 1990)
"The short-term effect of 20 mg of oral nifedipine on maternal and fetal hemodynamics was investigated in 12 women with pregnancy-induced hypertension."7.68Uterine and fetal flow velocity waveforms in hypertensive pregnancy: the effect of a single dose of nifedipine. ( Ekblad, UU; Erkkola, RU; Pirhonen, JP, 1990)
"The pharmacokinetics of oral nifedipine were studied in 15 women with pregnancy-induced hypertension in the third trimester of pregnancy to determine if the drug's disposition was different from that in nonpregnant patients."7.68Oral nifedipine pharmacokinetics in pregnancy-induced hypertension. ( Akl, SA; Prevost, RR; Sibai, BM; Whybrew, WD, 1992)
"Slow-release nifedipine has been used in the treatment of severe hypertension in 23 pregnant women."7.67Nifedipine as a second line antihypertensive drug in pregnancy. ( Beevers, DG; Constantine, G; Luesley, DM; Reynolds, AL, 1987)
"The calcium antagonist, nifedipine, was given orally to 21 women with acute episodes of severe hypertension during pregnancy or in the puerperium."7.67Treatment of severe pregnancy-associated hypertension with the calcium antagonist nifedipine. ( Redman, CW; Walters, BN, 1984)
"Nifedipine was found to be more effective than other antihypertensive medications to reduce blood pressure, particularly in patients with severe hypertension."6.82Comparative efficacy and safety of oral nifedipine with other antihypertensive medications in the management of hypertensive disorders of pregnancy: a systematic review and meta-analysis of randomized controlled trials. ( Adela, R; George, R; Joy, CA; Thomas, C; Undela, K; Varghese, B, 2022)
"In nifedipine-treated non-pregnant controls, only EC80 for adrenaline-induced aggregation decreased."6.68Nifedipine reduces thromboxane A2 production by platelets without changing aggregation in hypertensive pregnancy. ( Manninen, A, 1996)
"This was a nested cohort study of women with chronic hypertension and a singleton pregnancy recruited to the PANDA (Pregnancy And chronic hypertension: NifeDipine vs lAbetalol as antihypertensive treatment) study at one of three UK maternity units."5.30Longitudinal changes in vascular function parameters in pregnant women with chronic hypertension and association with adverse outcome: a cohort study. ( Chappell, LC; Cruickshank, JK; Khalil, A; Mills, C; Myers, JE; Nelson-Piercy, C; Seed, PT; Watt-Coote, I; Webster, LM, 2019)
"To assess the maternal and fetal outcome in women with mild to moderate chronic hypertension on antihypertensive drug (methyldopa or nifedipine) therapy compared to no medication."5.30Methyldopa versus nifedipine or no medication for treatment of chronic hypertension during pregnancy: A multicenter randomized clinical trial. ( Abdallah, S; Gaber, W; Gamal, A; Hamza, H; Marawan, H; Rezk, M; Salama, M, 2019)
" Methyldopa, labetalol, and nifedipine have been perceived safe to use during pregnancy and are therefore recommended in international guidelines for treatment of hypertension."5.22Pharmacokinetics of the most commonly used antihypertensive drugs throughout pregnancy methyldopa, labetalol, and nifedipine: a systematic review. ( Allegaert, K; Flint, RB; Mian, P; Schoenmakers, S; van de Vusse, D; Versmissen, J; Visser, W, 2022)
"Sixty-four women in the second half of pregnancy who were not in labor randomly received 10 mg nifedipine tablets (n = 55 studies) or 10 mg nifedipine capsules (n = 74 studies) if blood pressure was > or =170/110 mm Hg."5.10Efficacy and safety of nifedipine tablets for the acute treatment of severe hypertension in pregnancy. ( Brown, MA; Buddle, ML; Davis, GK; Farrell, T, 2002)
"To determine the efficacy of Nifedipine on postpartum blood Loss in patients with Pregnancy Induced Hypertension (PIH)."5.09[The effect of Nifedipine on postpartum blood loss in patients with pregnancy induced hypertension]. ( Liu, Y; Yang, X, 2000)
"The objective of the present study is to compare the effectiveness of transdermal glyceryl-trinitrate versus oral nifedipine in lowering blood pressure in patients affected by pregnancy-induced hypertension (PIH)."5.0924-hour ambulatory blood pressure monitoring: a comparison between transdermal glyceryl-trinitrate and oral nifedipine. ( Facchinetti, F; Menghini, S; Neri, I; Romanini, C; Valensise, H; Volpe, A, 1999)
"The safety of use of the calcium channel blocker nifedipine in pregnancy as it affects child development has not been well evaluated."5.09Nifedipine administered in pregnancy: effect on the development of children at 18 months. ( Bortolus, R; Chatenoud, L; Parazzini, F; Ricci, E, 2000)
"To determine whether nifedipine or prazosin is the more appropriate second-line antihypertensive agent in pregnancy."5.09Nifedipine or prazosin as a second agent to control early severe hypertension in pregnancy: a randomised controlled trial. ( Hall, DR; Odendaal, HJ; Smith, M; Steyn, DW, 2000)
"We sought to compare the efficacies of oral nifedipine and intravenous labetalol in the acute management of hypertensive emergencies of pregnancy."5.09A randomized, double-blind trial of oral nifedipine and intravenous labetalol in hypertensive emergencies of pregnancy. ( Chauhan, SP; Newman, RB; Scardo, JA; Vermillion, ST, 1999)
"To compare the effect of routine treatment with the calcium channel blocker nifedipine in mild to moderate hypertension in pregnancy."5.08Nifedipine versus expectant management in mild to moderate hypertension in pregnancy. Gruppo di Studio Ipertensione in Gravidanza. ( , 1998)
"Sublingual nifedipine was comparable to IV hydrallazine in the treatment of acute hypertension of pregnancy."5.08Sublingual nifedipine compared with intravenous hydrallazine in the acute treatment of severe hypertension in pregnancy: potential for use in rural practice. ( Jegasothy, R; Paranthaman, S, 1996)
"Thirty women with pregnancy-induced hypertension (PIH) scheduled for Caesarean section under general anaesthesia were studied to evaluate the efficacy of sublingual nifedipine in attenuating the pressor response to laryngoscopy and tracheal intubation."5.07Nifedipine attenuates the hypertensive response to tracheal intubation in pregnancy-induced hypertension. ( Bala, I; Batra, YK; Gopalan, S; Kumar, N, 1993)
"To compare nifedipine (group 1) with methyldopa (group 2) in the management of pregnancy induced hypertension (PIH)."5.07A comparison of nifedipine with methyldopa in pregnancy induced hypertension. ( Jayawardana, J; Lekamge, N, 1994)
"The effect of nifedipine on uteroplacental blood flow was investigated in nine hypertensive women in the trimester of pregnancy and compared with the effects of a placebo in nine similar hypertensive women."5.06The effect of sublingual nifedipine on uteroplacental blood flow in hypertensive pregnancy. ( Davey, DA; Davies, N; Lindow, SW; Smith, JA, 1988)
"The effect of nifedipine (Adalat; Bayer-Miles)--a calcium channel blocker, which has a well-established place in nonobstetric hypertension--was compared with dihydralazine in 33 primigravidas with severe hypertension of pregnancy."5.06Nifedipine in acute hypertensive emergencies in pregnancy. ( Becker, P; Moodley, J; Seabe, SJ, 1989)
" The incidence of severe hypertension was significantly lower when nifedipine (odds ratio, 0."5.05Comparative efficacy and safety of oral antihypertensive agents in pregnant women with chronic hypertension: a network metaanalysis. ( Bellos, I; Daskalakis, G; Loutradis, D; Papapanagiotou, A; Pergialiotis, V, 2020)
" Glyceryl trinitrate and labetalol were associated with fewer incidences of tachycardia and palpitation respectively than hydralazine."4.98Drugs for treating severe hypertension in pregnancy: a network meta-analysis and trial sequential analysis of randomized clinical trials. ( Sequeira, RP; Sridharan, K, 2018)
"Oral nifedipine is recommended along with labetalol and hydralazine for treatment of severe hypertension during pregnancy by most authorities."4.93Oral nifedipine versus intravenous labetalol for severe hypertension during pregnancy: a systematic review and meta-analysis. ( Gupta, N; Kirubakaran, R; Pareek, P; Shekhar, S, 2016)
"Oral nifedipine, and possibly labetalol and methyldopa, are suitable options for treatment of severe hypertension in pregnancy/postpartum."4.90Oral antihypertensive therapy for severe hypertension in pregnancy and postpartum: a systematic review. ( Firoz, T; Gordon, R; MacDonell, K; Magee, LA; Payne, BA; Vidler, M; von Dadelszen, P, 2014)
"The primary outcome indicators included the safety and antihypertensive efficacy of nifedipine in pregnancy; the effects of nifedipine on maternal/fetal hemodynamics; and the effect, if any, of nifedipine on perinatal outcome."4.79Use of nifedipine in the hypertensive diseases of pregnancy. ( Doering, PL; Hatton, RC; Levin, AC, 1994)
"The dihydropyridine group of calcium channel blockers (type II calcium blockers) and, specifically, nifedipine are safe for use in pregnancy."4.79Nifedipine and its indications in obstetrics and gynecology. ( Childress, CH; Katz, VL, 1994)
" The American College of Obstetricians and Gynecologists recommends that acute-onset, severe hypertension be treated with first line-therapy (intravenous labetalol, intravenous hydralazine or oral nifedipine) within 60 minutes to reduce risk of maternal morbidity and death."3.96Identification of factors associated with delayed treatment of obstetric hypertensive emergencies. ( Akerman, MB; Elsayad, A; Halpern, TA; Heiselman, CJ; Heo, HJ; Kantorowska, A; Muscat, JC; Sicuranza, GB; Vintzileos, AM, 2020)
"Doppler ultrasound and myography were utilised to assess uterine artery functional and structural changes pre-pregnancy and at gestational day 18 in SHRSP (untreated and nifedipine treated) and in the normotensive Wistar-Kyoto (WKY) rat."3.83Abnormal uterine artery remodelling in the stroke prone spontaneously hypertensive rat. ( Beattie, E; Delles, C; Graham, D; Griffin, S; Indahl, M; Morgan, H; Small, HY, 2016)
"Alpha-methyldopa is a regularly used antihypertensive drug during pregnancy."3.76[Methyldopa-induced acute reactive hepatitis in pregnancy, drug-metabolizing capacity of the liver]. ( Monostory, K; Ozsvár, Z; Solymossi, Z, 2010)
" She would like to know whether she can continue using metformin during the pregnancy and also is concerned about the effect of the gastric bypass surgery."3.74A 40-year-old woman with diabetes contemplating pregnancy after gastric bypass surgery. ( Coustan, DR, 2008)
"Study aim was assessment of clinical efficacy of mono therapy with nifedipine SR/GITS and combination of nifedipine SR/GITS and bisoprolol as well as investigation of functional state of sympathoadrenal system (SAS) in pregnant women with arterial hypertension."3.74[Clinical efficacy of antihypertensive therapy of pregnant women with arterial hypertension with long acting nifedipine and bisoprolol]. ( Brytkova, IaV; Bukhonkina, IuM; Pavlova, LN; Striuk, RI, 2008)
"To assess the variation of body composition at term in patients with normal pregnancy and patients with gestational hypertension (GH) treated with nifedipine."3.72Nifedipine-induced changes in body composition in hypertensive patients at term. ( Altomare, F; Andreoli, A; Arduini, D; De Lorenzo, A; Larciprete, G; Novelli, G; Valensise, H; Vasapollo, B, 2003)
"In 21 pregnancies complicated by pregnancy-induced hypertension (PIH) which was treated by antihypertensive drugs (labetalol, nifedipine), fetal behavioural recordings (quiet state, C1F; active state, C2F; no coincidence, NOC) and Doppler measurements of blood flow velocity in the umbilical artery (UA) (resistance index, RI) were made on two occasions (27-32 and 33-36 weeks of gestation)."3.70Pregnancy-induced hypertension, antihypertensive drugs and the development of fetal behavioural states. ( Bruschettini, PL; Gazzolo, D; Russo, A; Santi, F; Scopesi, F; Visser, GH, 1998)
"To describe the clinical course of pregnancies complicated by pulmonary hypertension and treated with the pulmonary vasodilators nifedipine and prostacyclin."3.70Pulmonary hypertension in pregnancy: treatment with pulmonary vasodilators. ( Easterling, TR; Ralph, DD; Schmucker, BC, 1999)
"To investigate the effect of 7 to 14 days of therapy with nifedipine (sustained-release preparation) on the 24-hour blood pressure patterns of pregnant women with pre-eclampsia or chronic hypertension, and to test the utility of blood pressure monitoring in modulating the timing and dosage of the drug."3.6924-hour blood pressure monitoring to evaluate the effects of nifedipine in pre-eclampsia and in chronic hypertension in pregnancy. ( Benedetto, C; Carandente, F; Chiarolini, L; Giarola, M; Maulà, V; Zonca, M, 1997)
" Description of their management, usage of nifedipine, and pregnancy outcome."3.69Sublingual nifedipine in human pregnancy. ( Gallery, ED; Györy, AZ, 1997)
"The efficacy of nifedipine in reducing the pressor response to AII suggests the involvement of intracellular free calcium in the vascular response to pressor agents in pregnancy, and supports the use of this drug in the treatment of pregnancy-induced hypertension."3.69Nifedipine reduces pressor responsiveness to angiotensin II in pregnant women. ( Conti, C; Garzetti, GG; Rezai, B; Romanini, C; Tranquilli, AL, 1994)
"Nifedipine was administered to 49 pregnant women with gestational hypertension as first-line therapy, and were longitudinally studied as paired observations for 3 or 10 day intervals of treatment with nifedipine until delivery."3.69The use of nifedipine as first-line hypotensive therapy in gestational hypertension. ( Caruso, A; De Carolis, MP; De Carolis, S; Ferrazzani, S; Mancinelli, S; Romano, D, 1994)
"The pharmacokinetics of oral nifedipine were studied in 15 women with pregnancy-induced hypertension in the third trimester of pregnancy to determine if the drug's disposition was different from that in nonpregnant patients."3.68Oral nifedipine pharmacokinetics in pregnancy-induced hypertension. ( Akl, SA; Prevost, RR; Sibai, BM; Whybrew, WD, 1992)
"The effect of lowering the maternal blood pressure with sublingual nifedipine on the fetal heart rate was studied in 51 patients with severe pregnancy-induced hypertension."3.68Effect of nifedipine on fetal heart rate in the treatment of severe pregnancy-induced hypertension. ( Fenakel, K; Friedman, A; Lurie, S, 1990)
"The short-term effect of 20 mg of oral nifedipine on maternal and fetal hemodynamics was investigated in 12 women with pregnancy-induced hypertension."3.68Uterine and fetal flow velocity waveforms in hypertensive pregnancy: the effect of a single dose of nifedipine. ( Ekblad, UU; Erkkola, RU; Pirhonen, JP, 1990)
"The calcium antagonist, nifedipine, was given orally to 21 women with acute episodes of severe hypertension during pregnancy or in the puerperium."3.67Treatment of severe pregnancy-associated hypertension with the calcium antagonist nifedipine. ( Redman, CW; Walters, BN, 1984)
"Slow-release nifedipine has been used in the treatment of severe hypertension in 23 pregnant women."3.67Nifedipine as a second line antihypertensive drug in pregnancy. ( Beevers, DG; Constantine, G; Luesley, DM; Reynolds, AL, 1987)
"Nifedipine was found to be more effective than other antihypertensive medications to reduce blood pressure, particularly in patients with severe hypertension."2.82Comparative efficacy and safety of oral nifedipine with other antihypertensive medications in the management of hypertensive disorders of pregnancy: a systematic review and meta-analysis of randomized controlled trials. ( Adela, R; George, R; Joy, CA; Thomas, C; Undela, K; Varghese, B, 2022)
"In nifedipine-treated non-pregnant controls, only EC80 for adrenaline-induced aggregation decreased."2.68Nifedipine reduces thromboxane A2 production by platelets without changing aggregation in hypertensive pregnancy. ( Manninen, A, 1996)
"Normal pregnancy is a complex and dynamic process that requires significant adaptation from the maternal system."2.66Hemodynamic Complications in Pregnancy: Preeclampsia and Beyond. ( Doherty, A; Kingdom, JC; McLaughlin, K, 2020)
"Pregnancy-induced hypertension is a major cause of maternal and fetal morbidity and mortality."2.61Hypertension and Pregnancy: Management and Future Risks. ( Jim, B; Reddy, S, 2019)
"Nifedipine is an effective and safe drug to use when tocolytic therapy is indicated for preterm labor."2.41Calcium channel blockers in the management of preterm labor and hypertension in pregnancy. ( Bos, JM; Dekker, GA; Geijn, HP; Lok, CA; Papatsonis, DN, 2001)
"We still do not have an ideal drug to treat acute severe hypertension in pregnancy."2.40Management of acute severe hypertension and encephalopathy. ( Mabie, WC, 1999)
"First, in premature labor, nifedipine is an appropriate alternative related with beta-mimetic or prostaglandin synthetase inhibitors agents, with good tocolytic properties and safe for both mother and baby."2.38[Nifedipine in gynecology and obstetrics]. ( Palma-Aguirre, JA; Rodríguez-Palomares, C, 1992)
"A review of the pathophysiology and treatment of pre-eclampsia indicates that vasospasm and vascular hyperreactivity are important elements in the disease process and its control."2.36Possible treatment of pre-eclampsia with calcium channel blocking agents. ( Zaret, GM, 1983)
"Nifedipine was the only aCCB used for this study population."1.38Antenatal calcium channel blocker exposure and subsequent patent ductus arteriosus in extremely low-birth-weight infants. ( Arzuaga, B; Lee, BH; McGuirl, J, 2012)
"Takayasu's arteritis is a chronic and non-specific disease of young women in reproductive age that primarily affects the aorta, its branches and the pulmonary artery."1.37[Takayasu's arteritis in pregnancy: report seven cases]. ( Carvajal-Valencia, JA; Chacón-Solís, AR; Estrada-Altamirano, A; Hernández-Pacheco, JA; Maya-Quiñones, JL; Valenzuela-Jirón, A, 2011)
"Pregnancy is associated with hemodynamic changes such as reduced vascular resistance and blood pressure."1.31Calcium channels contribute to the decrease in blood pressure of pregnant rats. ( Brochu, M; Cadorette, C; Poterek, M; Simaan, M; St-Louis, J, 2002)
"Primary pulmonary hypertension is a rare, incurable, and progressive disease."1.29Primary pulmonary hypertension in pregnancy: a case report. ( Asseryanis, E; Egarter, C; Kiss, H; Kneussl, M; Putz, D, 1995)

Research

Studies (95)

TimeframeStudies, this research(%)All Research%
pre-19909 (9.47)18.7374
1990's40 (42.11)18.2507
2000's17 (17.89)29.6817
2010's23 (24.21)24.3611
2020's6 (6.32)2.80

Authors

AuthorsStudies
George, R1
Thomas, C1
Joy, CA1
Varghese, B1
Undela, K1
Adela, R1
van de Vusse, D1
Mian, P1
Schoenmakers, S1
Flint, RB1
Visser, W1
Allegaert, K1
Versmissen, J1
Webster, LM2
Reed, K1
Myers, JE2
Burns, A1
Gupta, P1
Patel, P1
Wiesender, C1
Seed, PT2
Nelson-Piercy, C2
Chappell, LC2
Salama, M1
Rezk, M2
Gaber, W1
Hamza, H1
Marawan, H1
Gamal, A1
Abdallah, S1
Soares, C1
Gilson, M1
Kantorowska, A1
Heiselman, CJ1
Halpern, TA1
Akerman, MB1
Elsayad, A1
Muscat, JC1
Sicuranza, GB1
Vintzileos, AM1
Heo, HJ1
Bellos, I1
Pergialiotis, V1
Papapanagiotou, A1
Loutradis, D1
Daskalakis, G1
Doherty, A1
McLaughlin, K1
Kingdom, JC1
Mills, C1
Watt-Coote, I1
Khalil, A1
Cruickshank, JK1
Sridharan, K1
Sequeira, RP1
Reddy, S1
Jim, B1
Lemoine, ER1
Karumanchi, SA1
Alexander, JM1
Wilson, KL1
Ngamprasertwong, P1
Habli, M1
Boat, A1
Lim, FY1
Esslinger, H1
Ding, L1
Sadhasivam, S1
Firoz, T1
Magee, LA2
MacDonell, K1
Payne, BA1
Gordon, R1
Vidler, M1
von Dadelszen, P1
Vadhera, RB1
Simon, M1
Shi, Q1
Leng, W1
Yao, Q1
Mi, C1
Xing, A1
Shekhar, S1
Gupta, N2
Kirubakaran, R1
Pareek, P1
Clark, SM1
Dunn, HE1
Hankins, GD1
Sayyed, T1
Masood, A1
Dawood, R1
Small, HY1
Morgan, H1
Beattie, E1
Griffin, S1
Indahl, M1
Delles, C1
Graham, D1
Ozsvár, Z1
Solymossi, Z1
Monostory, K1
Holzgreve, H1
McGuirl, J1
Arzuaga, B1
Lee, BH1
Hernández-Pacheco, JA1
Estrada-Altamirano, A1
Valenzuela-Jirón, A1
Maya-Quiñones, JL1
Carvajal-Valencia, JA1
Chacón-Solís, AR1
Cheung, CS1
Li, TK1
Lee, CP1
Brown, MA1
Buddle, ML1
Farrell, T1
Davis, GK1
Valensise, H2
Larciprete, G1
Vasapollo, B1
Novelli, G1
Altomare, F1
Andreoli, A1
De Lorenzo, A1
Arduini, D1
Hodges, R1
Barkehall-Thomas, A1
Tippett, C1
van Veen, AJ1
Pelinck, MJ1
van Pampus, MG1
Erwich, JJ1
Papatsonis, DN2
Carbonne, B1
Dekker, GA2
Flenady, V1
King, JF1
Parasuraman, R1
Gandhi, MM1
Liversedge, NH1
Ugwumadu, A1
Dalmia, S1
Deka, D1
Mittal, S1
Striuk, RI1
Brytkova, IaV1
Bukhonkina, IuM1
Pavlova, LN1
Coustan, DR1
Zaret, GM1
Ulmsten, U1
Walters, BN1
Redman, CW3
Levin, AC1
Doering, PL1
Hatton, RC1
Kiss, H1
Egarter, C1
Asseryanis, E1
Putz, D1
Kneussl, M1
Jayawardana, J1
Lekamge, N1
Caruso, A1
Ferrazzani, S1
De Carolis, S1
Romano, D1
Mancinelli, S1
De Carolis, MP1
Manninen, A4
Vuorinen, P1
Laippala, P2
Tuimala, R3
Vapaatalo, H4
Tranquilli, AL1
Conti, C1
Rezai, B1
Garzetti, GG1
Romanini, C2
Childress, CH1
Katz, VL1
Ben-Ami, M1
Giladi, Y1
Shalev, E1
Impey, L1
Shalev, Y1
Ben-Hur, H1
Hagay, Z1
Blickstein, I1
Epstein, M1
Ayzenberg, O1
Gelven, A1
Caspi, A1
Ottman, EH1
Gall, SA1
Nootens, M1
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Kumar, N1
Batra, YK1
Bala, I1
Gopalan, S1
Jegasothy, R1
Paranthaman, S1
Wuorela, H1
Serra-Serra, V1
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Chandran, R1
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Zonca, M1
Giarola, M1
Maulà, V1
Chiarolini, L1
Carandente, F1
Gallery, ED1
Györy, AZ1
Hassall, JJ1
Langton, PE1
Millar, JA1
Gazzolo, D1
Visser, GH1
Russo, A1
Scopesi, F1
Santi, F1
Bruschettini, PL1
Hall, DR2
Odendaal, HJ2
Oei, SG1
Oei, SK1
Brölmann, HA1
Easterling, TR1
Ralph, DD1
Schmucker, BC1
Mabie, WC2
Neri, I1
Facchinetti, F1
Menghini, S1
Volpe, A1
Vermillion, ST1
Scardo, JA1
Newman, RB1
Chauhan, SP1
Smith, P1
Anthony, J1
Johanson, R1
Steyn, DW1
Smith, M1
Bortolus, R1
Ricci, E1
Chatenoud, L1
Parazzini, F1
Hussein, M1
Mooij, JM1
Roujouleh, H1
Lok, CA1
Bos, JM1
Geijn, HP1
Yang, X1
Liu, Y1
Simaan, M1
Cadorette, C1
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St-Louis, J1
Brochu, M1
Duggan, PM1
McCowan, LM1
Stewart, AW1
Palma-Aguirre, JA1
Rodríguez-Palomares, C1
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Metsä-Ketelä, T1
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Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Control Trial of Furosemide or Placebo With Usual Antihypertensives in the Antepartum Management of Severe Hypertension With Wide Pulse Pressure[NCT04615624]Phase 365 participants (Actual)Interventional2021-01-04Completed
A Comparison of Fetal Hemodynamic Measurements Between Pregnant Women Taking Anti-hypertensive Medication and Controls[NCT00759278]0 participants (Actual)Observational2008-08-31Withdrawn (stopped due to No participants)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

20 reviews available for nifedipine and Cardiovascular Pregnancy Complications

ArticleYear
Comparative efficacy and safety of oral nifedipine with other antihypertensive medications in the management of hypertensive disorders of pregnancy: a systematic review and meta-analysis of randomized controlled trials.
    Journal of hypertension, 2022, 10-01, Volume: 40, Issue:10

    Topics: Antihypertensive Agents; Female; Humans; Hypertension, Pregnancy-Induced; Nifedipine; Pregnancy; Pre

2022
Pharmacokinetics of the most commonly used antihypertensive drugs throughout pregnancy methyldopa, labetalol, and nifedipine: a systematic review.
    European journal of clinical pharmacology, 2022, Volume: 78, Issue:11

    Topics: Antihypertensive Agents; Female; Humans; Hypertension; Hypertension, Pregnancy-Induced; Labetalol; M

2022
Comparative efficacy and safety of oral antihypertensive agents in pregnant women with chronic hypertension: a network metaanalysis.
    American journal of obstetrics and gynecology, 2020, Volume: 223, Issue:4

    Topics: Abruptio Placentae; Amlodipine; Antihypertensive Agents; Atenolol; Cesarean Section; Chronic Disease

2020
Hemodynamic Complications in Pregnancy: Preeclampsia and Beyond.
    Clinics in perinatology, 2020, Volume: 47, Issue:3

    Topics: Anticonvulsants; Antihypertensive Agents; Aspirin; Delivery, Obstetric; Female; Fetal Growth Retarda

2020
Drugs for treating severe hypertension in pregnancy: a network meta-analysis and trial sequential analysis of randomized clinical trials.
    British journal of clinical pharmacology, 2018, Volume: 84, Issue:9

    Topics: Antihypertensive Agents; Dose-Response Relationship, Drug; Female; Headache; Humans; Hydralazine; Hy

2018
Hypertension and Pregnancy: Management and Future Risks.
    Advances in chronic kidney disease, 2019, Volume: 26, Issue:2

    Topics: Antihypertensive Agents; Aspirin; Cardiovascular Diseases; Chronic Disease; Diuretics; Female; Human

2019
Hypertensive emergencies of pregnancy.
    Obstetrics and gynecology clinics of North America, 2013, Volume: 40, Issue:1

    Topics: Antihypertensive Agents; Calcium Channel Blockers; Creatine; Diuretics; Emergency Medicine; Female;

2013
Oral antihypertensive therapy for severe hypertension in pregnancy and postpartum: a systematic review.
    BJOG : an international journal of obstetrics and gynaecology, 2014, Volume: 121, Issue:10

    Topics: Administration, Oral; Antihypertensive Agents; Female; Humans; Hydralazine; Hypertension, Pregnancy-

2014
Hypertensive emergencies in pregnancy.
    Clinical obstetrics and gynecology, 2014, Volume: 57, Issue:4

    Topics: Antihypertensive Agents; Eclampsia; Emergencies; Female; Humans; Hydralazine; Hypertension; Hyperten

2014
Oral nifedipine versus intravenous labetalol for the treatment of severe hypertension in pregnancy.
    International journal of cardiology, 2015, Jan-15, Volume: 178

    Topics: Administration, Oral; Antihypertensive Agents; Female; Humans; Hypertension; Infusions, Intravenous;

2015
Oral nifedipine versus intravenous labetalol for severe hypertension during pregnancy: a systematic review and meta-analysis.
    BJOG : an international journal of obstetrics and gynaecology, 2016, Volume: 123, Issue:1

    Topics: Administration, Intravenous; Administration, Oral; Adult; Antihypertensive Agents; Cost-Benefit Anal

2016
A review of oral labetalol and nifedipine in mild to moderate hypertension in pregnancy.
    Seminars in perinatology, 2015, Volume: 39, Issue:7

    Topics: Administration, Oral; Adult; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension,

2015
Possible treatment of pre-eclampsia with calcium channel blocking agents.
    Medical hypotheses, 1983, Volume: 12, Issue:4

    Topics: Calcium Channel Blockers; Eclampsia; Female; Fetus; Humans; Hypertension; Nifedipine; Placenta; Pre-

1983
Use of nifedipine in the hypertensive diseases of pregnancy.
    The Annals of pharmacotherapy, 1994, Volume: 28, Issue:12

    Topics: Female; Humans; Hydralazine; Hypertension; Nifedipine; Pre-Eclampsia; Pregnancy; Pregnancy Complicat

1994
Nifedipine and its indications in obstetrics and gynecology.
    Obstetrics and gynecology, 1994, Volume: 83, Issue:4

    Topics: Animals; Female; Fetus; Humans; Hypertension; Nifedipine; Pregnancy; Pregnancy Complications, Cardio

1994
Management of acute severe hypertension and encephalopathy.
    Clinical obstetrics and gynecology, 1999, Volume: 42, Issue:3

    Topics: Acute Disease; Antihypertensive Agents; Brain Diseases; Female; Humans; Hypertension; Nifedipine; Ni

1999
Calcium channel blockers in the management of preterm labor and hypertension in pregnancy.
    European journal of obstetrics, gynecology, and reproductive biology, 2001, Volume: 97, Issue:2

    Topics: Breast Feeding; Calcium Channel Blockers; Female; Humans; Hypertension; Maternal-Fetal Exchange; Nif

2001
[Nifedipine in gynecology and obstetrics].
    Ginecologia y obstetricia de Mexico, 1992, Volume: 60

    Topics: Amenorrhea; Antihypertensive Agents; Female; Fetus; Humans; Hypertension; Nifedipine; Obstetric Labo

1992
Doppler flow velocimetry in hypertension in pregnancy.
    Clinics in perinatology, 1991, Volume: 18, Issue:4

    Topics: Female; Fetus; Hemodynamics; Humans; Hypertension; Labetalol; Mass Screening; Nifedipine; Placenta;

1991
Antihypertensive drugs in pregnancy.
    Clinics in perinatology, 1985, Volume: 12, Issue:3

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Diazoxide; Diuretics; Female; Fetus; Humans; H

1985

Trials

21 trials available for nifedipine and Cardiovascular Pregnancy Complications

ArticleYear
Quantifying adherence to antihypertensive medication for chronic hypertension during pregnancy.
    Pregnancy hypertension, 2019, Volume: 17

    Topics: Adult; Antihypertensive Agents; Blood Pressure Determination; Chromatography, High Pressure Liquid;

2019
Methyldopa versus nifedipine or no medication for treatment of chronic hypertension during pregnancy: A multicenter randomized clinical trial.
    Pregnancy hypertension, 2019, Volume: 17

    Topics: Administration, Oral; Adult; Antihypertensive Agents; Egypt; Female; Humans; Hypertension; Hypertens

2019
Longitudinal changes in vascular function parameters in pregnant women with chronic hypertension and association with adverse outcome: a cohort study.
    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 2019, Volume: 53, Issue:5

    Topics: Adult; Antihypertensive Agents; Birth Weight; Black People; Blood Pressure; Chronic Disease; Cohort

2019
RETRACTED: Nicorandil vs nifedipine for the treatment of preterm labour: a randomized clinical trial.
    European journal of obstetrics, gynecology, and reproductive biology, 2015, Volume: 195

    Topics: Adolescent; Adult; Double-Blind Method; Female; Fetal Diseases; Headache; Humans; Nicorandil; Nifedi

2015
Efficacy and safety of nifedipine tablets for the acute treatment of severe hypertension in pregnancy.
    American journal of obstetrics and gynecology, 2002, Volume: 187, Issue:4

    Topics: Acute Disease; Blood Pressure; Capsules; Female; Humans; Hypertension; Nifedipine; Pregnancy; Pregna

2002
A comparison of nifedipine with methyldopa in pregnancy induced hypertension.
    The Ceylon medical journal, 1994, Volume: 39, Issue:2

    Topics: Adult; Female; Humans; Hypertension; Methyldopa; Nifedipine; Pregnancy; Pregnancy Complications, Car

1994
Nifedipine attenuates the hypertensive response to tracheal intubation in pregnancy-induced hypertension.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1993, Volume: 40, Issue:4

    Topics: Administration, Sublingual; Adult; Anesthesia, Intravenous; Apgar Score; Blood Gas Analysis; Blood P

1993
Sublingual nifedipine compared with intravenous hydrallazine in the acute treatment of severe hypertension in pregnancy: potential for use in rural practice.
    The journal of obstetrics and gynaecology research, 1996, Volume: 22, Issue:1

    Topics: Administration, Sublingual; Antihypertensive Agents; Calcium Channel Blockers; Female; Humans; Hydra

1996
Intraplatelet free calcium and calcium-regulating hormones in plasma are not related to the antihypertensive effect of nifedipine in hypertensive pregnancy.
    Pharmacology & toxicology, 1995, Volume: 77, Issue:5

    Topics: Adult; Blood Platelets; Calcium; Calcium Channel Blockers; Contraceptive Agents; Female; Humans; Hyd

1995
Nifedipine reduces thromboxane A2 production by platelets without changing aggregation in hypertensive pregnancy.
    Pharmacology & toxicology, 1996, Volume: 78, Issue:6

    Topics: Adult; Antihypertensive Agents; Blood Platelets; Blood Pressure; Female; Humans; Hypertension; In Vi

1996
The addition of a diuretic to anti-hypertensive therapy for early severe hypertension in pregnancy.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 1998, Volume: 60, Issue:1

    Topics: Adult; Amiloride; Antihypertensive Agents; Diuretics; Drug Combinations; Drug Therapy, Combination;

1998
Nifedipine versus expectant management in mild to moderate hypertension in pregnancy. Gruppo di Studio Ipertensione in Gravidanza.
    British journal of obstetrics and gynaecology, 1998, Volume: 105, Issue:7

    Topics: Adult; Birth Weight; Calcium Channel Blockers; Delayed-Action Preparations; Female; Gestational Age;

1998
24-hour ambulatory blood pressure monitoring: a comparison between transdermal glyceryl-trinitrate and oral nifedipine.
    Hypertension in pregnancy, 1999, Volume: 18, Issue:1

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Analysis of Variance; Female; Humans; Hypert

1999
A randomized, double-blind trial of oral nifedipine and intravenous labetalol in hypertensive emergencies of pregnancy.
    American journal of obstetrics and gynecology, 1999, Volume: 181, Issue:4

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Blood Pressure; Calcium Channel Blockers;

1999
Nifedipine or prazosin as a second agent to control early severe hypertension in pregnancy: a randomised controlled trial.
    BJOG : an international journal of obstetrics and gynaecology, 2000, Volume: 107, Issue:6

    Topics: Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hypertension; Ni

2000
Nifedipine administered in pregnancy: effect on the development of children at 18 months.
    BJOG : an international journal of obstetrics and gynaecology, 2000, Volume: 107, Issue:6

    Topics: Calcium Channel Blockers; Child Development; Female; Follow-Up Studies; Humans; Hypertension; Infant

2000
[The effect of Nifedipine on postpartum blood loss in patients with pregnancy induced hypertension].
    Zhonghua fu chan ke za zhi, 2000, Volume: 35, Issue:3

    Topics: Calcium Channel Blockers; Female; Humans; Hypertension; Nifedipine; Postpartum Hemorrhage; Pregnancy

2000
Antihypertensive drug effects on placental flow velocity waveforms in pregnant women with severe hypertension.
    The Australian & New Zealand journal of obstetrics & gynaecology, 1992, Volume: 32, Issue:4

    Topics: Arteries; Blood Flow Velocity; Double-Blind Method; Female; Humans; Hydralazine; Hypertension; Nifed

1992
The effect of nifedipine on fetal umbilical artery Doppler waveforms in pregnancies complicated by hypertension.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1991, Feb-16, Volume: 79, Issue:4

    Topics: Blood Flow Velocity; Blood Pressure; Double-Blind Method; Female; Heart Rate, Fetal; Humans; Hyperte

1991
Nifedipine in acute hypertensive emergencies in pregnancy.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1989, Sep-16, Volume: 76, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Blood Pressure; Dihydralazine; Emergencies; Female; Humans; Hypert

1989
The effect of sublingual nifedipine on uteroplacental blood flow in hypertensive pregnancy.
    British journal of obstetrics and gynaecology, 1988, Volume: 95, Issue:12

    Topics: Adult; Blood Flow Velocity; Blood Pressure; Female; Humans; Hypertension; Nifedipine; Placenta; Preg

1988

Other Studies

54 other studies available for nifedipine and Cardiovascular Pregnancy Complications

ArticleYear
Nifedipine-Induced Shock in Pregnancy With Aortic Stenosis.
    Annals of internal medicine, 2020, 02-04, Volume: 172, Issue:3

    Topics: Aortic Valve Stenosis; Calcium Gluconate; Chest Pain; Electrocardiography; Female; Fetofetal Transfu

2020
Identification of factors associated with delayed treatment of obstetric hypertensive emergencies.
    American journal of obstetrics and gynecology, 2020, Volume: 223, Issue:2

    Topics: Administration, Intravenous; Administration, Oral; Adult; After-Hours Care; Antihypertensive Agents;

2020
Committee Opinion No. 692 Summary: Emergent Therapy for Acute-Onset, Severe Hypertension During Pregnancy and the Postpartum Period.
    Obstetrics and gynecology, 2017, Volume: 129, Issue:4

    Topics: Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Drug Administration Routes; E

2017
Committee Opinion No. 692: Emergent Therapy for Acute-Onset, Severe Hypertension During Pregnancy and the Postpartum Period.
    Obstetrics and gynecology, 2017, Volume: 129, Issue:4

    Topics: Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Drug Administration Routes; E

2017
Oral regimen management of acute hypertension in pregnancy.
    Lancet (London, England), 2019, 09-21, Volume: 394, Issue:10203

    Topics: Antihypertensive Agents; Female; Humans; Hypertension; Labetalol; Methyldopa; Nifedipine; Pregnancy;

2019
Maternal hypotension during fetoscopic surgery: incidence and its impact on fetal survival outcomes.
    TheScientificWorldJournal, 2013, Volume: 2013

    Topics: Adult; Cohort Studies; Female; Fetal Death; Fetofetal Transfusion; Fetoscopy; Humans; Hypotension; I

2013
Oral nifedipine or intravenous labetalol for severe hypertension?
    BJOG : an international journal of obstetrics and gynaecology, 2016, Volume: 123, Issue:1

    Topics: Antihypertensive Agents; Female; Humans; Hypertension, Pregnancy-Induced; Labetalol; Nifedipine; Pra

2016
Abnormal uterine artery remodelling in the stroke prone spontaneously hypertensive rat.
    Placenta, 2016, Volume: 37

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Female; Gestational Age; Hypertension; Nifedipine;

2016
[Methyldopa-induced acute reactive hepatitis in pregnancy, drug-metabolizing capacity of the liver].
    Orvosi hetilap, 2010, Mar-14, Volume: 151, Issue:11

    Topics: Adrenergic alpha-Agonists; Adult; Antihypertensive Agents; Aryl Hydrocarbon Hydroxylases; Blood Pres

2010
[Hypertensive urgency or hypertensive emergency?].
    MMW Fortschritte der Medizin, 2010, Mar-18, Volume: 152, Issue:11

    Topics: Adult; Antihypertensive Agents; Blood Pressure Determination; Emergencies; Female; Follow-Up Studies

2010
Antenatal calcium channel blocker exposure and subsequent patent ductus arteriosus in extremely low-birth-weight infants.
    Pediatric cardiology, 2012, Volume: 33, Issue:1

    Topics: Calcium Channel Blockers; Case-Control Studies; Ductus Arteriosus, Patent; Female; Humans; Infant, N

2012
[Takayasu's arteritis in pregnancy: report seven cases].
    Ginecologia y obstetricia de Mexico, 2011, Volume: 79, Issue:3

    Topics: Adult; Antihypertensive Agents; Cesarean Section; Female; Fetal Growth Retardation; Follow-Up Studie

2011
Maternal atrial fibrillation after sequential use of nifedipine and atosiban for treatment of preterm labor: case report.
    European journal of obstetrics, gynecology, and reproductive biology, 2013, Volume: 166, Issue:2

    Topics: Adult; Atrial Fibrillation; Drug Therapy, Combination; Female; Humans; Nifedipine; Obstetric Labor,

2013
Nifedipine-induced changes in body composition in hypertensive patients at term.
    European journal of obstetrics, gynecology, and reproductive biology, 2003, Feb-10, Volume: 106, Issue:2

    Topics: Adult; Blood Pressure; Body Composition; Body Water; Calcium Channel Blockers; Electric Impedance; F

2003
Maternal hypoxia associated with nifedipine for threatened preterm labour.
    BJOG : an international journal of obstetrics and gynaecology, 2004, Volume: 111, Issue:4

    Topics: Adult; Dyspnea; Female; Heart Septal Defects, Ventricular; Humans; Hypoxia; Nifedipine; Obstetric La

2004
Severe hypotension and fetal death due to tocolysis with nifedipine.
    BJOG : an international journal of obstetrics and gynaecology, 2005, Volume: 112, Issue:4

    Topics: Adult; Female; Fetal Death; Humans; Hypotension; Nifedipine; Obstetric Labor, Premature; Pregnancy;

2005
Severe hypotension and fetal death due to tocolysis with nifedipine.
    BJOG : an international journal of obstetrics and gynaecology, 2005, Volume: 112, Issue:11

    Topics: Female; Fetal Death; Humans; Hypotension; Nifedipine; Pregnancy; Pregnancy Complications, Cardiovasc

2005
Nifedipine tocolysis associated atrial fibrillation responds to DC cardioversion.
    BJOG : an international journal of obstetrics and gynaecology, 2006, Volume: 113, Issue:7

    Topics: Adult; Atrial Fibrillation; Electric Countershock; Female; Humans; Nifedipine; Obstetric Labor, Prem

2006
Nifedipine-tocolysis-associated atrial fibrillation responds to DC cardioversion.
    BJOG : an international journal of obstetrics and gynaecology, 2007, Volume: 114, Issue:2

    Topics: Atrial Fibrillation; Calcium Channel Blockers; Electric Countershock; Female; Humans; Nifedipine; Pr

2007
Successful maternal and fetal outcome in a pregnancy with type V Takayasu's aortoarteritis.
    Archives of gynecology and obstetrics, 2008, Volume: 277, Issue:2

    Topics: Adult; Antihypertensive Agents; Arterial Occlusive Diseases; Calcium Channel Blockers; Diuretics; Fe

2008
[Clinical efficacy of antihypertensive therapy of pregnant women with arterial hypertension with long acting nifedipine and bisoprolol].
    Kardiologiia, 2008, Volume: 48, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Bisoprolol; Blood Pressure; Calcium Channel Blockers; Delayed-Ac

2008
A 40-year-old woman with diabetes contemplating pregnancy after gastric bypass surgery.
    JAMA, 2008, Jun-04, Volume: 299, Issue:21

    Topics: Adult; Antihypertensive Agents; Breast Feeding; Diabetes Mellitus, Type 2; Female; Gastric Bypass; G

2008
Treatment of normotensive and hypertensive patients with preterm labor using oral nifedipine, a calcium antagonist.
    Archives of gynecology, 1984, Volume: 236, Issue:2

    Topics: Adult; Female; Humans; Hypertension; Infant, Newborn; Nifedipine; Obstetric Labor, Premature; Pregna

1984
Treatment of severe pregnancy-associated hypertension with the calcium antagonist nifedipine.
    British journal of obstetrics and gynaecology, 1984, Volume: 91, Issue:4

    Topics: Adolescent; Adult; Blood Pressure; Female; Humans; Hypertension; Nifedipine; Pilot Projects; Pregnan

1984
Primary pulmonary hypertension in pregnancy: a case report.
    American journal of obstetrics and gynecology, 1995, Volume: 172, Issue:3

    Topics: Adult; Female; Heparin, Low-Molecular-Weight; Humans; Hypertension, Pulmonary; Nifedipine; Pregnancy

1995
The use of nifedipine as first-line hypotensive therapy in gestational hypertension.
    Minerva ginecologica, 1994, Volume: 46, Issue:5

    Topics: Adult; Female; Gestational Age; Humans; Hypertension; Infant, Newborn; Nifedipine; Pre-Eclampsia; Pr

1994
Atrial natriuretic peptide and cyclic guanosine-3'5'-monophosphate in hypertensive pregnancy and during nifedipine treatment.
    Pharmacology & toxicology, 1994, Volume: 74, Issue:3

    Topics: Administration, Oral; Adult; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Female; Humans;

1994
Nifedipine reduces pressor responsiveness to angiotensin II in pregnant women.
    Clinical and experimental obstetrics & gynecology, 1994, Volume: 21, Issue:1

    Topics: Adult; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Nifedipine; Pregnancy; Pregnanc

1994
The combination of magnesium sulphate and nifedipine: a cause of neuromuscular blockade.
    British journal of obstetrics and gynaecology, 1994, Volume: 101, Issue:3

    Topics: Adult; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hypertension; Magnesium Sulfate

1994
Severe hypotension and fetal distress following sublingual administration of nifedipine to a patient with severe pregnancy induced hypertension at 33 weeks.
    British journal of obstetrics and gynaecology, 1993, Volume: 100, Issue:10

    Topics: Adult; Female; Fetal Distress; Humans; Hypertension; Hypotension; Nifedipine; Pregnancy; Pregnancy C

1993
Successful delivery following myocardial ischemia during the second trimester of pregnancy.
    Clinical cardiology, 1993, Volume: 16, Issue:10

    Topics: Acute Disease; Adult; Atenolol; Cardiac Catheterization; Coronary Angiography; Female; Heparin; Huma

1993
Myocardial infarction in the third trimester of pregnancy secondary to an aortic valve thrombus.
    Obstetrics and gynecology, 1993, Volume: 81, Issue:5 ( Pt 2)

    Topics: Adult; Aortic Valve; Female; Heart Valve Prosthesis; Heparin; Humans; Myocardial Infarction; Nifedip

1993
Successful management of labor and delivery in primary pulmonary hypertension.
    The American journal of cardiology, 1993, May-01, Volume: 71, Issue:12

    Topics: Adenosine; Adult; Delivery, Obstetric; Female; Humans; Hypertension, Pulmonary; Nifedipine; Pregnanc

1993
The effect of nifedipine and methyldopa on maternal cerebral circulation.
    British journal of obstetrics and gynaecology, 1997, Volume: 104, Issue:5

    Topics: Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Cerebral Arteries; Cerebrovascular Cir

1997
24-hour blood pressure monitoring to evaluate the effects of nifedipine in pre-eclampsia and in chronic hypertension in pregnancy.
    British journal of obstetrics and gynaecology, 1997, Volume: 104, Issue:6

    Topics: Adult; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Chronic Dise

1997
Sublingual nifedipine in human pregnancy.
    Australian and New Zealand journal of medicine, 1997, Volume: 27, Issue:5

    Topics: Administration, Sublingual; Apgar Score; Birth Weight; Calcium Channel Blockers; Female; Humans; Hyp

1997
Withdrawal of nifedipine capsules: jeopardising the treatment of acute severe hypertension in pregnancy?
    The Medical journal of Australia, 1998, Jan-05, Volume: 168, Issue:1

    Topics: Acute Disease; Australia; Calcium Channel Blockers; Contraindications; Drug Labeling; Female; Humans

1998
Withdrawal of nifedipine capsules: jeopardising the treatment of acute severe hypertension in pregnancy?
    The Medical journal of Australia, 1998, Jan-05, Volume: 168, Issue:1

    Topics: Acute Disease; Administration, Oral; Administration, Sublingual; Blood Pressure; Calcium Channel Blo

1998
Withdrawal of nifedipine capsules: jeopardising the treatment of acute severe hypertension in pregnancy?
    The Medical journal of Australia, 1998, Jan-05, Volume: 168, Issue:1

    Topics: Acute Disease; Administration, Oral; Australia; Blood Pressure; Calcium Channel Blockers; Capsules;

1998
Pregnancy-induced hypertension, antihypertensive drugs and the development of fetal behavioural states.
    Early human development, 1998, Jan-09, Volume: 50, Issue:2

    Topics: Antihypertensive Agents; Cohort Studies; Embryo, Mammalian; Embryonic and Fetal Development; Female;

1998
Myocardial infarction during nifedipine therapy for preterm labor.
    The New England journal of medicine, 1999, Jan-14, Volume: 340, Issue:2

    Topics: Adult; Calcium Channel Blockers; Female; Humans; Myocardial Infarction; Nifedipine; Obstetric Labor,

1999
Pulmonary hypertension in pregnancy: treatment with pulmonary vasodilators.
    Obstetrics and gynecology, 1999, Volume: 93, Issue:4

    Topics: Adult; Antihypertensive Agents; Epoprostenol; Female; Humans; Hypertension, Pulmonary; Nifedipine; P

1999
Nifedipine in pregnancy.
    BJOG : an international journal of obstetrics and gynaecology, 2000, Volume: 107, Issue:3

    Topics: Drug Interactions; Female; Humans; Hypertension; Nifedipine; Pregnancy; Pregnancy Complications, Car

2000
Factor analysis, including antihypertensive medication, of the outcome of pregnancy in pregnancy-associated hypertension.
    Kidney & blood pressure research, 2001, Volume: 24, Issue:2

    Topics: Antihypertensive Agents; Apgar Score; Cesarean Section; Comorbidity; Disease Susceptibility; Female;

2001
Calcium channels contribute to the decrease in blood pressure of pregnant rats.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2002
The effect of nifedipine and dipyridamole on the Doppler blood flow waveforms of umbilical and uterine arteries in hypertensive pregnant women.
    Asia-Oceania journal of obstetrics and gynaecology, 1992, Volume: 18, Issue:2

    Topics: Adult; Arteries; Blood Flow Velocity; Dipyridamole; Female; Humans; Hypertension; Nifedipine; Pregna

1992
Oral nifedipine pharmacokinetics in pregnancy-induced hypertension.
    Pharmacotherapy, 1992, Volume: 12, Issue:3

    Topics: Administration, Oral; Adult; Female; Half-Life; Humans; Hypertension; Metabolic Clearance Rate; Nife

1992
Nifedipine increases urinary excretion of prostacyclin metabolite in hypertensive pregnancy.
    Pharmacology & toxicology, 1991, Volume: 69, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Blood Pressure; Catecholamines; Creatinine; Dinoprostone; Epopr

1991
Blood pressure, plasma renin activity and calcium metabolism in hypertensive pregnancy: the effect of nifedipine.
    International journal of clinical pharmacology research, 1990, Volume: 10, Issue:6

    Topics: Adult; Blood Pressure; Calcium; Electrolytes; Female; Humans; Hypertension; Nifedipine; Pregnancy; P

1990
Uterine and fetal flow velocity waveforms in hypertensive pregnancy: the effect of a single dose of nifedipine.
    Obstetrics and gynecology, 1990, Volume: 76, Issue:1

    Topics: Adult; Apgar Score; Birth Weight; Blood Flow Velocity; Cerebral Arteries; Cesarean Section; Female;

1990
Effect of nifedipine on fetal heart rate in the treatment of severe pregnancy-induced hypertension.
    American journal of perinatology, 1990, Volume: 7, Issue:3

    Topics: Female; Heart Rate, Fetal; Humans; Hypertension; Nifedipine; Pregnancy; Pregnancy Complications, Car

1990
Preeclampsia: platelets and antiplatelet therapy.
    Hospital practice (Office ed.), 1988, May-30, Volume: 23, Issue:5A

    Topics: Aspirin; Blood Coagulation; Blood Platelets; Diagnosis, Differential; Female; Fetus; Humans; Hyperte

1988
Nifedipine does not adversely affect uteroplacental blood flow in the hypertensive term-pregnant rat.
    American journal of obstetrics and gynecology, 1988, Volume: 159, Issue:6

    Topics: Animals; Female; Hemodynamics; Hypertension; Nifedipine; Placenta; Pregnancy; Pregnancy Complication

1988
Nifedipine as a second line antihypertensive drug in pregnancy.
    British journal of obstetrics and gynaecology, 1987, Volume: 94, Issue:12

    Topics: Adult; Atenolol; Delayed-Action Preparations; Drug Therapy, Combination; Female; Humans; Hypertensio

1987